Ontology
version info: 2013-05-31 (yyyy-mm-dd)
comment: The NPO was primarily developed by Dennis G. Thomas in collaboration with Nathan A. Baker and Rohit V. Pappu. This development was supported by the NIH through grants U54 CA119342 and U54 HG004028.
creator: Dennis G. Thomas
description: NanoParticle Ontology (NPO): An ontology for representing the knowledge underlying the description and characterization of nanoparticles.

synonym
type: AnnotationProperty
type: DatatypeProperty
comment: The property synonym is used to indicate an alternate name of a class or a class-level association in the NPO.
range: string

OLD_SOURCE_ROLE
type: AnnotationProperty
type: DatatypeProperty
comment: Used to support Merge and Retire

Editor_Note
type: AnnotationProperty
type: DatatypeProperty
comment: Used to support Merge and Retire

Concept_Status
type: AnnotationProperty
type: DatatypeProperty
comment: Used to support NCI Edit tab

dBXrefID
type: AnnotationProperty
type: DatatypeProperty
comment: The property dBXrefID is used to indicate the reference ID of a class from an external CV / ontology / database.

DesignNote
type: AnnotationProperty
type: DatatypeProperty
comment: Used to support Merge and Retire

Merge_Source
type: AnnotationProperty
type: DatatypeProperty
comment: Used to support Merge and Retire

OLD_CHILD
type: AnnotationProperty
type: DatatypeProperty
comment: Used to support Merge and Retire

OLD_PARENT
type: AnnotationProperty
type: DatatypeProperty
comment: Used to support Merge and Retire

Merge_Target
type: AnnotationProperty
type: DatatypeProperty
comment: Used to support Merge and Retire

Split_From
type: AnnotationProperty
type: DatatypeProperty
comment: Used to support Split

Merge_Into
type: AnnotationProperty
type: DatatypeProperty
comment: Used to support Merge and Retire

OLD_ROLE
type: AnnotationProperty
type: DatatypeProperty
comment: Used to support Merge and Retire

preferred_name
type: AnnotationProperty
type: DatatypeProperty
comment: The property preferred name is used to indicate the preferred name of a class or a class-level association in the NPO.
range: string

definition
type: AnnotationProperty
type: DatatypeProperty
comment: The property definition is used to indicate the meaning or definition of a class or a class-level association in the NPO.
range: string

FULL_SYN
type: AnnotationProperty
type: DatatypeProperty
comment: This property is in support of the NCI Edit Tab.
range: string

code
type: AnnotationProperty
type: DatatypeProperty
comment: It begins with the prefix "NPO_" followed by a number (e.g., NPO_250). The smallest code value is NPO_100 of class Cylinder.
comment: The property code is used to indicate a unique identification code for every class in the NPO.
range: string

symbol
type: AnnotationProperty
type: DatatypeProperty
comment: The property symbol is used to enter a symbol that denotes the name of an entity.

agent in
type: ObjectProperty
definition: Relation between a continuant and an occurrent in which the continuant participates in and causes the occurrence of that occurrent.
comment: This relation is taken from the Ontology for Biomedical Investigations (OBI: Version 2009-11-06 Philly (aka version 1.0) Release Candidate)
preferred name: agent in
sub property of: participates in

analyzes
type: ObjectProperty
definition: A relation that indicates the process, property, or substance analyzed in an assay.
preferred name: analyzes
sub property of: has relation to

bearer of
type: ObjectProperty
definition: A relation between an entity and a dependent continuant.
preferred name: bearer of
sub property of: has relation to
range: dependent_continuant

contained in
type: ObjectProperty
comment: (source): OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005)
definition: A relation between a material continuant and an immaterial continuant, when the material continuant at any given time is located in but shares no parts in common with the immaterial continuant at the same time.
comment: C contained_in C1; Cs are material continuants, C1s are immaterial continuants (holes, cavities): Every C at any given time is located in but shares no parts in common with C1 at the same time.
preferred name: contained in
sub property of: has relation to

contains
type: ObjectProperty
comment: (source): OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005)
definition: A reciprocal relation of contained_in, where given an immaterial continuant at some time, there is a material continuant contained in the immaterial continuant at the same time.
comment: C contains C1; Cs are immaterial continuants, C1s are material continuants: for all C, t, , if c is an instance of C at time t, then there is some c1 such that c1 is an instance of C1 and c1 contained_in c at t.
preferred name: contains
sub property of: has relation to

denoted by
type: ObjectProperty
definition: A relation which indicates the symbol that denotes something.
preferred name: denoted by
range: symbol
sub property of: has relation to

derives from
type: ObjectProperty
type: TransitiveProperty
definition: A relation between distinct material continuants when one succeeds the other across a temporal divide in such a way that at least a significant portion of the matter of the earlier continuant is inherited by the later.
comment: The temporal relation of derivation is more complex. Transformation, on the instance level, is just the relation of identity: each adult is identical to some child existing at some earlier time. Derivation on the instance-level is a relation holding between non-identicals. More precisely, it holds between distinct material continuants when one succeeds the other across a temporal divide in such a way that at least a biologically significant portion of the matter of the earlier continuant is inherited by the later. Thus we will have axioms to the effect that from c derives_from c1 we can infer that c and c1 are not identical and that there is some instant of time t such that c1 exists only prior to and c only subsequent to t. We will also be able to infer that the spatial region occupied by c as it begins to exist at t overlaps with the spatial region occupied by c1 as it ceases to exist in the same instant.
comment: [source]:OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005)
preferred name: derives from
sub property of: has relation to

determines property
type: ObjectProperty
definition: A relation which indicates the property determined by a characterization.
preferred name: determines property
domain: characterization
sub property of: has relation to
range: specifically_dependent_continuant

document attribute
type: ObjectProperty
preferred name: document attribute
sub property of: has relation to

function of
type: ObjectProperty
definition: A relationship that indicates the bearer inhering a function.
preferred name: function of
sub property of: inheres in
domain: function

has DOI
type: ObjectProperty
preferred name: has DOI
sub property of: document attribute

has PubMedID
type: ObjectProperty
preferred name: has PubMedID
sub property of: document attribute

has abstract
type: ObjectProperty
preferred name: has abstract
sub property of: document attribute

has agent
type: ObjectProperty
comment: (source): OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005)
definition: A relation which is between a process, a continuant and a time whenever the continuant is a participant in the process and is at the same time directly causally responsible for its occurrence.
comment: Only material continuants can fill the agent role, that if c fills the agent role at t, then c must have existed at times earlier than t, that it must exercise its agent role for an interval of time including t, and so on.
comment: P has_agent C; Ps are processes, Cs are material continuants. Every P involves some C as agent (the C is involved in and is causally responsible for the P)
preferred name: has agent
sub property of: has participant

has application
type: ObjectProperty
definition: A relation which indicates the application or use of an entity.
preferred name: has application
sub property of: has relation to

has author
type: ObjectProperty
preferred name: has author
sub property of: document attribute

has bond with
type: ObjectProperty
definition: A relationship to indicate that one atom has a covalent bond with another atom.
preferred name: has bond with
sub property of: has relation to

has component part
type: ObjectProperty
definition: A relation used between material continuants where one is composed of the other. In the NPO, this relation is used mostly for representing the composition of nanoparticle formulations or nanoparticles.
comment: C has_component_part C1, means that every instance c of C is prepared from some instances c1 of C1 and a significant material portion of c1 becomes part of the constituting material of c when c begins to exist.
preferred name: has component part
synonym: is composed of
sub property of: derives from

has conjugated component part
type: ObjectProperty
definition: A has_component_part type of relation, which is used to infer that a particular component in a nanoparticle formulation is attached or chemically conjugated to some other chemical components of the same nanoparticle formulation by a method of attachment.
synonym: has attached component part
preferred name: has conjugated component part
sub property of: has component part

has datum value
type: ObjectProperty
definition: A relation which indicates the value of a property that can be quantified.
preferred name: has datum value
range: datum value
sub property of: has relation to

has double bond with
type: ObjectProperty
definition: A relationship to indicate that one atom has a double covalent bond with another atom.
preferred name: has double bond with
sub property of: has bond with

has encapsulated component part
type: ObjectProperty
definition: A has_component_part type of relation, which is used to infer that a particular component (molecular structure or nanostructure) becomes encapsulated - due to non-covalent interactions - in a nanoparticle by a method of encapsulation.
preferred name: has encapsulated component part
sub property of: has component part

has endpoint of measurement
type: ObjectProperty
definition: A relation that indicates the endpoint measured with an assay.
preferred name: has endpoint of measurement
sub property of: has relation to

has entrapped component part
type: ObjectProperty
definition: A has_component_part type of relation, which is used to infer that a particular component (molecular structure or nanostructure) is entrapped - due to non-covalent interactions - in a nanoparticle by a method of entrapment.
preferred name: has entrapped component part
sub property of: has component part

has function
type: ObjectProperty
definition: A relationship that indicates the function inhering in an entity.
preferred name: has function
sub property of: bearer of
range: function
domain: independent_continuant

has identification type
type: ObjectProperty
definition: A relation which indicates the name of the type of identification, as well as other attributes of an entity.
preferred name: has identification type
sub property of: has relation to

has journal name
type: ObjectProperty
preferred name: has journal name
sub property of: document attribute

has output participant
type: ObjectProperty
definition: A relationship between a continuant and an occurrent that has other participating continuants, which holds if at every time t an instance of the occurrent is created, there is at least one instance of the continuant participating in it at time t1 > t, and it is formed / derived from the instances of those continuants that participate at time t.
preferred name: has output participant
sub property of: has participant

has part
type: ObjectProperty
type: TransitiveProperty
comment: (source): OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005)
comment: If C and C1 are continuant classes, then C has_part C1 means that every instance of C at any time has part some instances of C1 at the same time. [formal definition]: C has_part C1 holds true if and only if every continuant c that instantiates C at some time t, there is some continuant c1 that instantiates C1 at t such that c1 is part of c at t. Examples: fluorescein isothiocyanate has_part isothiocyanate group gold quantum dot has_part gold core-shell nanoparticle has_part core core-shell nanoparticle has_part shell
comment: If P and P1 are occurrent classes, then P has_part P1 means that every instance of P has part some instances of P1. [formal definition]:P has_part P1 if and only if every occurrent p that instantiates P there is some occurrent p1 that instantiates P1 such that p1 is part of p. Examples: covalent linkage has_part covalent interaction visualization of cellular uptake of nanoparticles has_part imaging of nanoparticles
definition: Transitive parthood relation in which one entity has itself, or another entity as a part, and the relation is valid for use only between continuants or between occurrents but not between a continuant and an occurrent.
preferred name: has part
sub property of: has relation to

has participant
type: ObjectProperty
comment: (source): OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005)
definition: A relationship between a continuant and an occurrent, which holds if at every time an instance of the occurrent is created, it has at least one instance of the continuant participating in it at the same time.
comment: Examples: nanoparticle-mediated drug delivery has_participant drug-loaded nanoparticle
comment: If P is an occurrent class and C a continuant class, then P has_participant C means that every instance of P involves some instances of C as participants. [formal definition]: P has_participant C hold true, if and only if every occurrent p that instantiates P there is some continuant c, and some time t, such that c instantiates C at t and p has participant c at t.
preferred name: has participant
sub property of: has relation to
range: continuant
domain: occurrent

has property
type: ObjectProperty
definition: A relation between an entity and a specifically dependent continuant.
preferred name: has property
sub property of: bearer of
range: specifically_dependent_continuant

has publication year
type: ObjectProperty
preferred name: has publication year
sub property of: document attribute

has quality
type: ObjectProperty
definition: A relation which indicates the quality inhering in an entity. It is a general relation between any class and subclasses of Quality.
preferred name: has quality
sub property of: bearer of
range: quality

has relation to
type: ObjectProperty
definition: A relationship to indicate that a class is related to another class.
preferred name: has relation to

has role
type: ObjectProperty
comment: If C is an independent continuant and C1 a role continuant class, then C has_role R1 means that every instance of C fills some instances of role C1 everytime the role is realized in a particular context.
definition: Relation between an independent continuant and a role.
comment: [source]: OBO Relation Ontology (release version 0.99, date 07:14:2006)
comment: e.g., X (molecular entity) has_role Y (role), i.e, X fills the role of Y
preferred name: has role
sub property of: bearer of
range: role

has single bond with
type: ObjectProperty
definition: A relationship to indicate that one atom has a single covalent bond with another atom.
preferred name: has single bond with
sub property of: has bond with

has temperature condition
type: ObjectProperty
definition: A relation that indicates the temperature at which a process is performed.
preferred name: has temperature condition
sub property of: has relation to

has time period
type: ObjectProperty
definition: A relation that indicates the duration for a process to occur.
preferred name: has time period
sub property of: has relation to

has title
type: ObjectProperty
preferred name: has title
sub property of: document attribute

has triple bond with
type: ObjectProperty
definition: A relationship to indicate that one atom has a triple covalent bond with another atom.
preferred name: has triple bond with
sub property of: has bond with

has unit of measure
type: ObjectProperty
definition: A relation which indicates the unit of a measured quantity.
synonym: has unit
preferred name: has unit of measure
sub property of: has relation to
inverse of: unit of
range: unit of measurement

inheres in
type: ObjectProperty
definition: A relation between a dependent continuant D and an entity E. D inheres_in E if: given any d that instantiates D at t, there exists some e that instantiates E at t and d *inheres_in* e at t. Here *inheres_in* is the primitive instance level relation. [source: OBI]
preferred name: inheres in
sub property of: has relation to
domain: dependent_continuant

inidicator of
type: ObjectProperty
definition: A relation that indicates the process or phenomenon signified by a measured endpoint of an assay.
preferred name: indicator of
sub property of: has relation to

is integral part of
type: ObjectProperty
type: TransitiveProperty
definition: A parthood relation that holds when C is part of C and C1 has part C, where C and C1 are continuant classes.
comment: [source]: OBO Relation Ontology (release version 0.99); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005)
comment: e.g.,carbon atom is_integral_part_of carbon (carbon is_a element)
preferred name: is integral part of
sub property of: has relation to

is realized in
type: ObjectProperty
definition: A relationship between a realizable entity and an occurrent.
comment: This relation is taken from the Ontology for Biomedical Investigations (OBI: Version 2009-11-06 Philly (aka version 1.0) Release Candidate)
synonym: executed during
synonym: has realization
synonym: is realized as
synonym: is realized by
preferred name: is realized in
sub property of: has relation to
domain: realizable_entity
range: occurrent

measure of
type: ObjectProperty
definition: A relation which indicates a qualitative or quantitative measure (estimate) of an entity based on measurement, calculation, or counting.
preferred name: measure of
sub property of: has relation to

negatively regulates
type: ObjectProperty
definition: A relation between two occurrents where one negatively regulates the other.
synonym: blocks
synonym: inhibits
preferred name: negatively regulates
sub property of: has relation to
domain: occurrent
range: occurrent

parameter determined from
type: ObjectProperty
definition: A relation which indicates the type of process that determines the value of a parameter.
preferred name: parameter determined from
sub property of: property determined from

part of
type: ObjectProperty
type: TransitiveProperty
comment: If C and C1 are continuant classes, then C part_of C1 means that every instance of C (c) at any time is part of some instances of C1 (c1) at the same time []. Note that whenever we read "some instances" it should be understood as reading "one or more instances". [formal definition]: C part_of C1 holds true if and only if every continuant c that instantiates C at some time t, there is some continuant c1 that instantiates C1 at t such that c is part of c1 at t. Examples: carboxyl group part_of carboxylic acid dendrimer generation layer part_of dendrimer hydrophobic core of lipid bilayer part_of lipid bilayer hollow core of nanocage part_of nanocage
comment: If P and P1 are occurrent classes, then P part_of P1 means that every instance of P is part of some instances of P1. [formal definition]: P part_of P1 holds true if and only if every occurrent p that instantiates P there is some process p1 that instantiates P1 such that p is part of p1. Examples: drug release from nanoparticle during systemic circulation part_of systemic circulation of drug-loaded nanoparticle
definition: Transitive parthood relation in which one entity is part of another entity, and the relation is valid for use between continuants or between occurrents but not between a continuant and an occurrent.
comment: [source]: OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005)
synonym: is part of
preferred name: part of
sub property of: has relation to

participates in
type: ObjectProperty
definition: A relationship between a continuant and an occurrent, which holds iff at every time an instance of the continuant is created, it participates in at least one instance of the occurrent at the same time.
comment: Example: catalyst participates_in catalytic reaction fluorometer participates_in measurement of fluorescence intensity
comment: If C is a continuant class and P an occurrent class, then C participates_in P means that every instance of C participates in some instances of P. [formal definition]: C participates_in P if and only if every continuant c that instantiates C there is some occurrent p, and some time t, such that p instantiates P and c participates in p at t.
comment: [source]: OBO Relation Ontology (release version 0.99, date 07:14:2006)
synonym: is_participant_of
preferred name: participates in
sub property of: has relation to
domain: continuant
range: occurrent

positively regulates
type: ObjectProperty
definition: A relation between two occurrents where one positively regulates the other.
preferred name: positively regulates
sub property of: has relation to
range: occurrent
domain: occurrent

property determined from
type: ObjectProperty
definition: A relation which indicates the type of process that determines a qualitative or quantitative measure of the property.
preferred name: property determined from
sub property of: has relation to

property of
type: ObjectProperty
definition: A relation which indicates the entity which bears a property.
preferred name: property of
sub property of: inheres in

quality of
type: ObjectProperty
definition: A relation between a quality and its bearer.
synonym: quality inheres in
preferred name: quality of
sub property of: inheres in
domain: quality

realizes
type: ObjectProperty
definition: A relation between an occurrent to a realizable entity.
synonym: is realization of
preferred name: realizes
sub property of: has relation to
inverse of: is realized in
range: realizable_entity
domain: occurrent

regulates
type: ObjectProperty
definition: A relationship between two occurrents where one regulates the other.
preferred name: regulates
sub property of: has relation to
domain: occurrent
range: occurrent

role of
type: ObjectProperty
definition: A relationship indicating the bearer inhering a role.
preferred name: role of
sub property of: inheres in
domain: role

stimulus causes response
type: ObjectProperty
definition: A relationship that indicates the response caused by a stimulus. (e.g., the response caused by the action of a stimulus on a nanoparticle)
preferred name: stimulus causes response
sub property of: has relation to

technique is based on
type: ObjectProperty
definition: A relationship which indicates the principle based on which a technique is used.
preferred name: technique is based on
sub property of: has relation to

technique used for
type: ObjectProperty
definition: A relation which indicates the process for which the technique is used.
preferred name: technique used for
domain: technique
sub property of: has application

unit of
type: ObjectProperty
definition: A relation that indicates the quantity associated with a unit of measure. It is an inverse relation of "has unit of measure".
preferred name: unit of
sub property of: has relation to
domain: unit of measurement

uses instrument
type: ObjectProperty
definition: A relation which indicates that the type of instrument used in a process.
preferred name: uses instrument
range: instrument
sub property of: has relation to

uses reagent
type: ObjectProperty
definition: A relation which indicates the reagent used in an assay.
preferred name: uses reagent
sub property of: has relation to

uses technique
type: ObjectProperty
definition: A relation which indicates the technique used for accomplishing a purpose.
preferred name: uses technique
range: technique
sub property of: has relation to

value specified at
type: ObjectProperty
definition: This relation is used to indicate other datum values that have to be specified/recorded when a particular datum value is recorded.
preferred name: value specified at
domain: datum value
range: datum value
sub property of: has relation to

atomic Number
type: DatatypeProperty
type: FunctionalProperty
definition: The number of protons in an atom.
preferred name: atomic number
range: int

cylindrical shape
type: Class
subclass of: shape
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shape formed by the surface of a 3-dimensional object, where points on the surface are at a fixed distance from a given straight line (axis of the cylinder).</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cylindrical shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C63806
code: NPO_100
synonym: cylindrical
preferred name: cylindrical shape

deoxyribonucleic acid
type: Class
subclass of: nucleic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nucleic acid composed of nucleotides containing deoxyribose sugar and linked by phosphodiester bonds. DNA contains the genetic information of organisms.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>deoxyribonucleic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: DNA
code: NPO_1002
preferred name: deoxyribonucleic acid

halogen
type: Class
equivalent class: Class
  union of: chlorine
  union of: iodine
  union of: fluorine
  union of: astatine
  union of: bromine
subclass of: non-metal
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A non-metal which is any of the following elements: astatine, bromine, chlorine, fluorine, iodine.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>halogen</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_101
preferred name: halogen

nano-object
type: Class
subclass of: nanomaterial
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A nanomaterial which has one, two, or three external dimensions in the nanoscale size range.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nano-object</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1018
editor note: This term had the preferred name "nanostructure" in version 2010-10-31.
preferred name: nano-object

homoatomic
type: Class
subclass of: independent specific individual quality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a molecular entity because it consists of one or more atoms of the same element.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>homoatomic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1019
preferred name: homoatomic

prolate spheroidal shape
type: Class
subclass of: spheroidal shape
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spheroidal shape, which is generated by half-revolution of an ellipse around its major axis.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>prolate spheroidal shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_102
preferred name: prolate spheroidal shape

polyatomic
type: Class
subclass of: independent specific individual quality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a molecular entity because it consists of more than one atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>polyatomic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1020
preferred name: polyatomic

monoatomic
type: Class
subclass of: independent specific individual quality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a molecular entity because it consists of only one atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>monoatomic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1021
preferred name: monoatomic

heteroatomic
type: Class
subclass of: independent specific individual quality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a molecular entity because it consists of two or more chemical elements.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>heteroatomic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1022
preferred name: heteroatomic

aluminium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: aluminium
disjoint with: bohrium atom
disjoint with: iodine atom
disjoint with: manganese atom
disjoint with: sodium atom
disjoint with: lanthanum atom
disjoint with: francium atom
disjoint with: caesium atom
disjoint with: nickel atom
disjoint with: fluorine atom
disjoint with: niobium atom
disjoint with: neon atom
disjoint with: promethium atom
disjoint with: mercury atom
disjoint with: zinc atom
disjoint with: potassium atom
disjoint with: neptunium atom
disjoint with: chlorine atom
disjoint with: dubnium atom
disjoint with: radium atom
disjoint with: uranium atom
disjoint with: zirconium atom
disjoint with: rubidium atom
disjoint with: osmium atom
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom

methotrexate-loaded nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: Class
      intersection of: methotrexate
      intersection of: Restriction
        on property: has role
        some values from: payload agent role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is loaded with methotrexate.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>methotrexate-loaded nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_104
preferred name: methotrexate-loaded nanoparticle

Group 16 Element
type: Class
equivalent class: Class
  union of: polonium
  union of: oxygen
  union of: tellurium
  union of: sulfur
  union of: selenium
subclass of: group element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 16 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Group 16 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Group 16 Element
code: NPO_105
synonym: chalogen

hydrophilic core of liposome
type: Class
subclass of: core site
subclass of: Restriction
  on property: part of
  some values from: liposome
disjoint with: hydrophobic core of lipid bilayer
disjoint with: hydrophilic space between lipid bilayers
disjoint with: dendrimer core
disjoint with: hollow core of nanocapsule
disjoint with: nuclear core of nanocell
disjoint with: hollow core of nanoshell
disjoint with: hollow core of nanocage
disjoint with: hydrophobic core of micelle
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The aqueous space enclosed by lipid bilayer of a liposome.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydrophilic core of liposome</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_106
preferred name: hydrophilic core of liposome

strontium
type: Class
subclass of: element
disjoint with: francium
disjoint with: chlorine
disjoint with: seaborgium
disjoint with: iridium
disjoint with: californium
disjoint with: rhodium
disjoint with: germanium
disjoint with: mendelevium
disjoint with: iodine
disjoint with: nitrogen
disjoint with: meitnerium
disjoint with: lawrencium
disjoint with: einsteinium
disjoint with: beryllium
disjoint with: mercury
disjoint with: boron
disjoint with: dysprosium
disjoint with: radon
disjoint with: magnesium
disjoint with: calcium
disjoint with: protactinium
disjoint with: fluorine
disjoint with: neodymium
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium

bohrium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 107
disjoint with: iodine atom
disjoint with: manganese atom
disjoint with: sodium atom
disjoint with: lanthanum atom
disjoint with: francium atom
disjoint with: caesium atom
disjoint with: nickel atom
disjoint with: fluorine atom
disjoint with: niobium atom
disjoint with: neon atom
disjoint with: promethium atom
disjoint with: mercury atom
disjoint with: zinc atom
disjoint with: potassium atom
disjoint with: neptunium atom
disjoint with: chlorine atom
disjoint with: dubnium atom
disjoint with: radium atom
disjoint with: uranium atom
disjoint with: zirconium atom
disjoint with: rubidium atom
disjoint with: osmium atom
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom

lipid-coated nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: Class
      intersection of: lipid
      intersection of: Restriction
        on property: has role
        some values from: nanoparticle surface modifying role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a coating agent composed of a lipid.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>lipid-coated nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_109
preferred name: lipid-coated nanoparticle

carboxylate
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: carboxylate group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carboxylate is an organic compound which is characterized by the presence of a carboxylate group. It has the structure R-C(=O)-[O-], where 'R' denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carboxylate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_110
preferred name: carboxylate

francium
type: Class
subclass of: element
disjoint with: chlorine
disjoint with: seaborgium
disjoint with: iridium
disjoint with: californium
disjoint with: rhodium
disjoint with: germanium
disjoint with: mendelevium
disjoint with: iodine
disjoint with: nitrogen
disjoint with: meitnerium
disjoint with: lawrencium
disjoint with: einsteinium
disjoint with: beryllium
disjoint with: mercury
disjoint with: boron
disjoint with: dysprosium
disjoint with: radon
disjoint with: magnesium
disjoint with: calcium
disjoint with: protactinium
disjoint with: fluorine
disjoint with: neodymium
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium

carbon molecular entity
type: Class
equivalent class: Class
  intersection of: carbon group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: carbon
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of carbon.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carbon molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1113
preferred name: carbon molecular entity

multi-walled nanotube
type: Class
subclass of: nanotube
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanotube which consists of multiple layers or sheets of hexagonal arrays of an element or molecule, rolled in on themselves to form concentric seamless cylinders with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>multi-walled nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_112
preferred name: multi-walled nanotube

acyl chloride group
type: Class
subclass of: acyl halide group
subclass of: Restriction
  on property: has part
  some values from: chloro group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acyl halide group in which the halogen atom is a chlorine atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>acyl chloride group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_113
preferred name: acyl chloride group

lipophilic
type: Class
subclass of: hydrophobic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrophobic property by virtue of which the molecule is able to combine with or dissolve in lipids or fats.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>lipophilic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_114
preferred name: lipophilic
synonym: lipophilicity

nanodevice
type: Class
subclass of: engineered nanomaterial
definition: <ncicp:ComplexDefinition><ncicp:def-definition>An engineered nanomaterial which has an end-directed activity/function.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanodevice</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_115
preferred name: nanodevice

polydispersity index
type: Class
subclass of: parameter
subclass of: Restriction
  on property: has unit of measure
  some values from: weight ratio
subclass of: Restriction
  on property: measure of
  some values from: polydispersity
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative measure of polydispersity. It is a measure of the distribution of molecular mass in a given polymer sample or the distribution of particle sizes in a particulate sample. In polymeric samples, the polydispersity index is calculated as the weight average molecular weight divided by the number average molecular weight.</ncicp:def-definition><ncicp:Definition_Review_Date>100727</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>polydispersity index</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1155
synonym: PDI
preferred name: polydispersity index

weight ratio
type: Class
subclass of: dimensionless unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dimensionless unit which denotes the ratio of weights.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>weight ratio</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1156
preferred name: weight ratio

magnetic flux
type: Class
subclass of: magnetism
subclass of: Restriction
  on property: has unit of measure
  some values from: magnetic flux unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quantitative measure of magnetism, which is a measure of the strength of a magnetic field over a given area.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>magnetic flux</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1158
preferred name: magnetic flux

magnetic flux unit
type: Class
subclass of: unit of measurement
subclass of: Restriction
  on property: unit of
  some values from: magnetic flux
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of measurement for magnetic flux.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>magnetic flux unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1159
preferred name: magnetic flux unit
synonym: unit of magnetic flux

magnetic flux density
type: Class
subclass of: magnetism
subclass of: Restriction
  on property: has unit of measure
  some values from: magnetic flux density unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The amount of magnetic flux in a unit area perpendicular to the direction of magnetic flow.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>magnetic flux density</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1163
preferred name: magnetic flux density

magnetic flux density unit
type: Class
subclass of: unit of measurement
subclass of: Restriction
  on property: unit of
  some values from: magnetic flux density
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of measurement for magnetic flux density.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>magnetic flux density unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1164
preferred name: magnetic flux density unit
synonym: unit of magnetic flux density

concentration
type: Class
subclass of: dependent general individual quality
subclass of: Restriction
  on property: quality of
  some values from: Class
    union of: chemical component
    union of: solute
subclass of: Restriction
  on property: has unit of measure
  some values from: concentration unit
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a substance by virtue of the amount of it there is mixed with another substance.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>concentration</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1167
DB xref ID: PATO:0000033
preferred name: concentration

sulfonyl chloride group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: sulfonyl chloride derivative
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which is derived by the removal of one chlorine atom from chlorosulfuric acid, and has the structure -S(=O)(=O)-Cl. The group is characteristic of sulfonyl chloride derivatives.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>sulfonyl chloride group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_117
preferred name: sulfonyl chloride group

molecular weight
type: Class
subclass of: independent specific individual quality
subclass of: Restriction
  on property: has unit of measure
  some values from: mass unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The sum of the relative atomic masses of the constituent atoms of a molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>molecular weight</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: MW
code: NPO_1171
preferred name: molecular weight

chemical interaction
type: Class
subclass of: force
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A force of interaction between atoms, ions, molecules or groups.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>chemical interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_119
synonym: chemical bonding
preferred name: chemical interaction

molarity
type: Class
subclass of: concentration
subclass of: Restriction
  on property: has unit of measure
  some values from: unit of molarity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The number of moles of a solute dissolved in a liter of solution.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>molarity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1190
synonym: molar concentration
preferred name: molarity

molality
type: Class
subclass of: concentration
subclass of: Restriction
  on property: has unit of measure
  some values from: unit of molality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The number of moles of solute dissolved in one kilogram of solvent.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>molality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1191
synonym: molal concentration
preferred name: molality

normality
type: Class
subclass of: concentration
subclass of: Restriction
  on property: has unit of measure
  some values from: unit of normality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Concentration of a solution expressed in gram equivalents of solute per liter.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>normality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1192
synonym: normal concentration
preferred name: normality

cell concentration
type: Class
subclass of: dependent specific individual quality
subclass of: Restriction
  on property: has unit of measure
  some values from: unit of cell concentration
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Concentration, which is the amount of cells in a medium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cell concentration</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1193
preferred name: cell concentration

IC50
type: Class
subclass of: toxicity
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of toxicity which is the concentration of a drug or inhibitor that is required to inhibit a biological process or a participant's activity in that process by half. The realization of this realizable entity is the 50% inhibition of a biological process or the activity (molecular function) of a biological occurring chemical entity (e.g., gene, gene product)</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>IC50</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: IC50
code: NPO_1195
synonym: half maximal inhibitory concentration

LC-50
type: Class
subclass of: toxicity
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of toxicity which is the concentration of a chemical or biologic preparation that is likely to cause death in 50% of animals or cells being tested. The realization of this realizable entity is the death of 50% of animals or cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>LC-50</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: LC-50
synonym: LD-50
DB xref ID: NCIT:C16788
code: NPO_1196
synonym: lethal concentration - 50%
synonym: lethal dose - 50%

basic pH
type: Class
subclass of: pH
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>pH of value between 7 and 14.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>basic pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1199
synonym: alkaline pH
preferred name: basic pH

polar aminoacid
type: Class
equivalent class: Class
  intersection of: aminoacid
  intersection of: Restriction
    on property: has part
    some values from: Class
      intersection of: alpha-aminoacid sidechain
      intersection of: Restriction
        on property: has quality
        some values from: polar
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aminoacid which is polar in nature.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>polar aminoacid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_120
preferred name: polar aminoacid

acidic pH
type: Class
subclass of: pH
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>pH of value between 0 and 7.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>acidic pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1200
preferred name: acidic pH

neutral pH
type: Class
subclass of: pH
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>pH of value equal to 7.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>neutral pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1201
preferred name: neutral pH

alkaline
type: Class
subclass of: acidity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A qualitative measure of acidity in the basic pH range.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>alkaline</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1202
preferred name: alkaline
synonym: basic

acidic
type: Class
subclass of: acidity
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A qualitative measure of acidity in the acidic pH range.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>acidic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1203
preferred name: acidic

isoelectric point
type: Class
subclass of: pH
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The pH at which a particular molecule or surface carries no net electrical charge.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>isoelectric point</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1204
preferred name: isoelectric point

cells per microliter
type: Class
subclass of: unit of cell concentration
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of cell concentration which is equal to one cell in a volume of 1 microliter.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cells per microliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C67242
code: NPO_1206
preferred name: cells per microliter
symbol: cells/µL

alkali earth metal
type: Class
equivalent class: Class
  union of: strontium
  union of: beryllium
  union of: magnesium
  union of: calcium
  union of: barium
  union of: radium
subclass of: metal
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 2 (IUPAC style) of the periodic table: beryllium (Be), magnesium (Mg), calcium (Ca), strontium (Sr), barium (Ba) and radium (Ra).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>alkali earth metal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_121
preferred name: alkali earth metal
synonym: alkaline earth metal

amount of substance
type: Class
subclass of: independent general individual quality
subclass of: Restriction
  on property: has unit of measure
  some values from: substance unit
subclass of: Restriction
  on property: quality of
  some values from: Class
    union of: chemical component
    union of: chemical substance by physical state
    union of: molecular entity
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality which denotes the amount of substance (matter).</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>amount of substance</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1217
preferred name: amount of substance

body weight
type: Class
subclass of: independent specific individual quality
subclass of: Restriction
  on property: has unit of measure
  some values from: Class
    union of: kilogram
    union of: gram
    union of: milligram
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Weight inhering in the body of an animal species.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>body weight</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1219
preferred name: body weight

nanorod
type: Class
subclass of: two-dimensional nanoparticle
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A two-dimensional nanoparticle which is shaped like a long dowel and has diameter measured in the nanoscale.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanorod</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C62373
code: NPO_122
comment: [NCI_Thesaurus definition]: Nanoscale structures that are shaped like long dowels. The structures have a diameter that is measured in the nanoscale with an extended length parameter.
preferred name: nanorod

tumor weight
type: Class
subclass of: independent specific individual quality
subclass of: Restriction
  on property: quality of
  some values from: tumor
subclass of: Restriction
  on property: has unit of measure
  some values from: mass unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Weight inhering in a tumor.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tumor weight</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1220
preferred name: tumor weight

surface area
type: Class
subclass of: area
subclass of: Restriction
  on property: quality of
  some values from: material boundary
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Area of an object's surface.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>surface area</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1235
preferred name: surface area

anti-adhesion agent
type: Class
equivalent class: Class
  intersection of: antimetastatic agent
  intersection of: Restriction
    on property: has role
    some values from: Class
      intersection of: inhibitor role
      intersection of: Restriction
        on property: is realized in
        some values from: negative regulation of cell adhesion
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antimetastic agent, which prevents metastasis by interfering with the aggregation of tumor cells.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>anti-adhesion agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C2197
code: NPO_124
preferred name: anti-adhesion agent

Actinide
type: Class
equivalent class: Class
  union of: californium
  union of: mendelevium
  union of: lawrencium
  union of: einsteinium
  union of: protactinium
  union of: berkelium
  union of: thorium
  union of: neptunium
  union of: actinium
  union of: americium
  union of: plutonium
  union of: fermium
  union of: nobelium
  union of: uranium
  union of: curium
subclass of: inner transition element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An inner transition element which is any element in the series of 15 radioactive metallic elements with atomic numbers 89 (actinium) to 103 (lawrencium).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Actinide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Actinide
code: NPO_125

square nanometer
type: Class
subclass of: area unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An area unit which is equal to 10^[-18] m^[2].</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>square nanometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1252
symbol: nm^[2]
preferred name: square nanometer

nanotube
type: Class
subclass of: two-dimensional nanoparticle
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A two-dimensional nanoparticle which consists of one or more sheets of hexagonal arrays of an element or molecule, rolled into seamless cylinders with capped ends.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C73455
code: NPO_126
preferred name: nanotube

microgram per milliliter
type: Class
subclass of: mass density unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in micrograms divided by the volume in milliliters.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>microgram per milliliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1267
preferred name: microgram per milliliter
synonym: micrograms per milliliter
symbol: µg/mL

microgram per microliter
type: Class
subclass of: mass density unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in micrograms divided by the volume in microliters.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>microgram per microliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1268
preferred name: microgram per microliter
synonym: micrograms per microliter
symbol: µg/µL

nanoparticle surface modifying role
type: Class
subclass of: component role in nanoparticle
subclass of: Restriction
  on property: is realized in
  some values from: surface modification of nanoparticle
subclass of: Restriction
  on property: role of
  some values from: surface modifying agent
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Role of a surface modifying agent that is attached to the surface of a nanoparticle in a nanoparticle formulation.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanoparticle surface modifying role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_127
preferred name: nanoparticle surface modifying role

iodoacetyl group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: iodoacetyl compound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iodoacetyl group is an organic group which has the structure -C(=O)-CH2-I. The group is characteristic of an iodoacetyl molecule in which it is attached either to a hydrogen atom or a carbon atom via single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>iodoacetyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_128
preferred name: iodoacetyl group

time quality
type: Class
subclass of: independent general individual quality
subclass of: Restriction
  on property: has unit of measure
  some values from: time unit
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a continuant bearer by virtue of its relation to time during its existence.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>time quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1285
preferred name: time quality

age
type: Class
subclass of: time quality
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A time quality inhering in a bearer by virtue of how long it has existed.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>age</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1286
DB xref ID: PATO:0000011
preferred name: age

chlorine
type: Class
subclass of: element
disjoint with: seaborgium
disjoint with: iridium
disjoint with: californium
disjoint with: rhodium
disjoint with: germanium
disjoint with: mendelevium
disjoint with: iodine
disjoint with: nitrogen
disjoint with: meitnerium
disjoint with: lawrencium
disjoint with: einsteinium
disjoint with: beryllium
disjoint with: mercury
disjoint with: boron
disjoint with: dysprosium
disjoint with: radon
disjoint with: magnesium
disjoint with: calcium
disjoint with: protactinium
disjoint with: fluorine
disjoint with: neodymium
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium

electric charge
type: Class
subclass of: independent general individual quality
subclass of: Restriction
  on property: has unit of measure
  some values from: electric charge unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A property of matter responsible for electrical phenomena.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>electric charge</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1292
synonym: charge
preferred name: electric charge

electric charge unit
type: Class
subclass of: unit of measurement
subclass of: Restriction
  on property: unit of
  some values from: electric charge
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a measure of the quantity of charge.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>electric charge unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1293
synonym: charge unit
preferred name: electric charge unit

selective estrogen receptor modulator
type: Class
equivalent class: Class
  intersection of: antineoplastic agent
  intersection of: Restriction
    on property: has function
    some values from: Class
      intersection of: binding function
      intersection of: Restriction
        on property: is realized in
        some values from: estrogen receptor binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anticancer drug that acts like estrogen on some tissues but blocks the effect of estrogen on other tissues.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>selective estrogen receptor modulator</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C1821
code: NPO_130
preferred name: selective estrogen receptor modulator

zeta potential
type: Class
subclass of: electric potential
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The potential difference between the bulk dispersion medium (liquid) and the stationary layer of liquid near the surface of the dispersed particulate.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>zeta potential</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C62354
code: NPO_1302
preferred name: zeta potential

statcoulomb
type: Class
subclass of: electric charge unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric charge unit which which is approximately equal to 3.33564 × 10^[?10] C.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>statcoulomb</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
symbol: Fr
synonym: Franklin
code: NPO_1303
synonym: e.s.u.
synonym: electrostatic unit of charge
symbol: statC
preferred name: statcoulomb

ampere hour
type: Class
subclass of: electric charge unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of electric charge where one ampere-hour is equal to 3600 coulombs.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ampere hour</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
symbol: Ah
code: NPO_1304
synonym: amp hour
preferred name: ampere hour

positive charge
type: Class
subclass of: electric charge
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric charge quality which signifies a deficiency of electrons in the bearer.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>positive charge</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1305
preferred name: positive charge
synonym: positively charged

negative charge
type: Class
subclass of: electric charge
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric charge quality which signifies a surplus of electrons in the bearer.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>negative charge</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1306
preferred name: negative charge
synonym: negatively charged

neutral charge
type: Class
subclass of: electric charge
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric charge quality which signifies zero net charge in the bearer.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>neutral charge</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1307
preferred name: neutral charge
synonym: neutrally charged

rate
type: Class
subclass of: realizable_entity
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity which inheres in a continuant or a group of continuants under certain conditions, and it is realized through the occurrence of a process, activity or interaction per unit time.</ncicp:def-definition><ncicp:Definition_Review_Date>100429</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>rate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1308
DB xref ID: PATO:0000161
preferred name: rate

tumor suppression rate
type: Class
subclass of: mass rate
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The rate of suppression in tumor growth.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tumor suppression rate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1309
synonym: rate of tumor suppression
preferred name: tumor suppression rate

Period 1 Element
type: Class
equivalent class: Class
  union of: hydrogen
  union of: helium
subclass of: period element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element in the first row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Period 1 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_131
preferred name: Period 1 Element

mass rate
type: Class
subclass of: rate
subclass of: Restriction
  on property: has unit of measure
  some values from: mass rate unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The rate of change or movement in the mass (amount of matter) of a physical object.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>mass rate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1310
preferred name: mass rate

mass rate unit
type: Class
subclass of: unit of measurement
subclass of: Restriction
  on property: unit of
  some values from: mass rate
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A measure of the change or movement of mass per unit time.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>mass rate unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1311
preferred name: mass rate unit
synonym: unit of mass rate

kilogram per day
type: Class
subclass of: mass rate unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of mass rate expressed as kilograms per day.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>kilogram per day</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1312
symbol: kg/day
preferred name: kilogram per day
synonym: kilograms per day

electrophoretic mobility
type: Class
subclass of: mobility
subclass of: Restriction
  on property: has unit of measure
  some values from: unit of electrophoretic mobility
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Mobility of a charged particle in electrophoresis, measured as the rate of migration (usually in cm/s) per unit electric field strength (usually V/cm) of the charged particle.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>electrophoretic mobility</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1315
preferred name: electrophoretic mobility

unit of electrophoretic mobility
type: Class
subclass of: unit of measurement
subclass of: Restriction
  on property: unit of
  some values from: electrophoretic mobility
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of measure of electrophoretic mobility.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>unit of electrophoretic mobility</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1317
preferred name: unit of electrophoretic mobility

square centimeter per volt per second
type: Class
subclass of: unit of electrophoretic mobility
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of electrophoretic mobility of a charged particle moving with a velocity of 1cm/s in an electric field of strength equal to 1 volt/s.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>square centimeter per volt per second</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1318
symbol: cm^[2]/(V s)
preferred name: square centimeter per volt per second

sulfonyl chloride derivative
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: sulfonyl chloride group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A sulfonyl chloride derivative is an organic compound which is characterized by the presence of a sulfonyl chloride group. It has the structure R-S(=O)(=O)-Cl, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>sulfonyl chloride derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_132
preferred name: sulfonyl chloride derivative

mole percentage
type: Class
subclass of: percent
symbol: % mol
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A percentage unit of molar concentration which is equal to 100 times the mole fraction (number of moles of solute in proportion to the total number of moles in a solution.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>mole percentage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1327
symbol: mol %
preferred name: mole percentage
synonym: percent of total moles

seaborgium
type: Class
subclass of: element
disjoint with: iridium
disjoint with: californium
disjoint with: rhodium
disjoint with: germanium
disjoint with: mendelevium
disjoint with: iodine
disjoint with: nitrogen
disjoint with: meitnerium
disjoint with: lawrencium
disjoint with: einsteinium
disjoint with: beryllium
disjoint with: mercury
disjoint with: boron
disjoint with: dysprosium
disjoint with: radon
disjoint with: magnesium
disjoint with: calcium
disjoint with: protactinium
disjoint with: fluorine
disjoint with: neodymium
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium

efficiency
type: Class
subclass of: realizable_entity
subclass of: Restriction
  on property: has unit of measure
  some values from: percent
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity inhering in a bearer by virtue of ratio of the bearer's output to the bearer's input.</ncicp:def-definition><ncicp:Definition_Review_Date>100429</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>efficiency</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1333
DB xref ID: PATO:0001029
preferred name: efficiency

loading efficiency
type: Class
subclass of: efficiency
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a material entity by virtue of it having the capacity to carry an amount of another material entity.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>loading efficiency</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1334
preferred name: loading efficiency

transfection efficiency
type: Class
subclass of: efficiency
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The efficiency inhering in a bearer's ability to facilitate transfection.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>transfection efficiency</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1335
preferred name: transfection efficiency

encapsulation efficiency
type: Class
subclass of: efficiency
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The efficiency inhering in a nanomaterial or supramolecular structure by virtue of its capacity to encapsulate an amount of molecular entity, isotope or nanomaterial.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>encapsulation efficiency</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1336
preferred name: encapsulation efficiency

tumor volume
type: Class
subclass of: tumor size
subclass of: Restriction
  on property: has unit of measure
  some values from: volume unit
subclass of: Restriction
  on property: quality of
  some values from: tumor
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 3-D extent quality of the amount of 3-dimensional space a tumor occupies.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tumor volume</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1337
preferred name: tumor volume

toxicity
type: Class
subclass of: realizable_entity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity inhering in a bearer which causes harm to the growth and functioning of cells, tissues, organs and the body.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>toxicity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C27990
code: NPO_1338
preferred name: toxicity

immunotoxicity
type: Class
subclass of: toxicity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Toxicity that impairs or damages the immune system.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>immunotoxicity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C63814
code: NPO_1339
preferred name: immunotoxicity

cytotoxicity
type: Class
subclass of: toxicity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Toxicity that impairs or damages cells, and it is a desired property for the killing of growing tumor cells.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cytotoxicity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C27988
code: NPO_1340
preferred name: cytotoxicity

drug toxicity
type: Class
subclass of: toxicity
subclass of: Restriction
  on property: inheres in
  some values from: anticancer drug
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Toxicity that inheres in a drug which causes adverse effects, when the drug is used therapeutically or diagnostically.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>drug toxicity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C27955
code: NPO_1341
preferred name: drug toxicity

cell viability
type: Class
subclass of: viability
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Viability of a cell to proliferate, grow, divide, or repair damaged cell components.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cell viability</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1343
preferred name: cell viability

chemical composition
type: Class
subclass of: independent general individual quality
subclass of: Restriction
  on property: quality of
  some values from: Class
    union of: chemical substance by physical state
    union of: fiat material part
    union of: nanomaterial
    union of: material boundary
    union of: molecular entity
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in an object by virtue of the type, quantities or relative ratios of chemical components of the inhering entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100701</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO:0000025 (composition)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>chemical composition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1344
preferred name: chemical composition

purity
type: Class
subclass of: chemical composition
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A composition quality which is the degree to which an object bearer is free of contaminants or heterogeneous components.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>purity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1345
preferred name: purity

amplitude of sound wave
type: Class
subclass of: wave amplitude
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>The maximum magnitude (value without regard to sign) of the disturbance of a sound wave.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>amplitude of sound wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1351
DB xref ID: PATO:0001521
synonym: amplitude of sound
preferred name: amplitude of sound wave
synonym: sound amplitude

characterization
type: Class
subclass of: experiment
subclass of: Restriction
  on property: part of
  some values from: study
subclass of: Restriction
  on property: has part
  some values from: assay
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An experiment performed to determine the distinctive characteristics (property / behavior) or essential features of a material entity.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1355
preferred name: characterization

physicochemical characterization
type: Class
subclass of: characterization
subclass of: Restriction
  on property: has part
  some values from: physical assay
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of characterization, which is performed to determine the physicochemical (material and structural) properties of an object.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>physicochemical characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1356
preferred name: physicochemical characterization

in vitro characterization
type: Class
subclass of: characterization
subclass of: Restriction
  on property: has part
  some values from: in vitro assay
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of characterization, which is performed to determine a property/quality that indicates the behavior of a material entity in vitro.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>in vitro characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1357
preferred name: in vitro characterization

in vivo characterization
type: Class
subclass of: characterization
subclass of: Restriction
  on property: has part
  some values from: in vivo assay
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of characterization, which is performed to determine a property/quality that indicates the behavior of a material entity in vivo.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>in vivo characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1358
preferred name: in vivo characterization

molecular weight characterization
type: Class
subclass of: physicochemical characterization
subclass of: Restriction
  on property: determines property
  some values from: molecular weight
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of physical characterization, which is performed to determine the molecular weight of a molecular entity.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>molecular weight characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1359
preferred name: molecular weight characterization

antimitotic agent
type: Class
equivalent class: Class
  intersection of: antineoplastic agent
  intersection of: Restriction
    on property: has role
    some values from: Class
      intersection of: inhibitor role
      intersection of: Restriction
        on property: is realized in
        some values from: negative regulation of mitosis
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic agent that kills cancer cells by interfering with mitosis.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>antimitotic agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: MESH: D050256
DB xref ID: NCIT: C273
code: NPO_136
preferred name: antimitotic agent

purity characterization
type: Class
subclass of: physicochemical characterization
subclass of: Restriction
  on property: determines property
  some values from: purity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of physical characterization, which is performed to determine the purity of a chemical substance.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>purity characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1360
preferred name: purity characterization

shape characterization
type: Class
subclass of: physicochemical characterization
subclass of: Restriction
  on property: determines property
  some values from: shape
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of physical characterization, which is performed to determine the shape of an object.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>shape characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1361
preferred name: shape characterization

size characterization
type: Class
subclass of: physicochemical characterization
subclass of: Restriction
  on property: determines property
  some values from: size
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of physical characterization, which is performed to determine the size of an object.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>size characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1362
preferred name: size characterization

surface characterization
type: Class
subclass of: physicochemical characterization
subclass of: Restriction
  on property: determines property
  some values from: surface property
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of physical characterization, which is performed to determine the surface property of an object.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>surface characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1363
preferred name: surface characterization

surface property
type: Class
equivalent class: Class
  intersection of: specifically_dependent_continuant
  intersection of: Restriction
    on property: inheres in
    some values from: material boundary
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A property inhering in the surface of an object.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>surface property</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1364
preferred name: surface property

aspect ratio
type: Class
subclass of: dimensionless unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dimensionless unit which denotes the ratio of longest and shortest dimensions of an object.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>aspect ratio</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1365
preferred name: aspect ratio

average diameter
type: Class
subclass of: diameter
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A measure of diameter obtained by dividing a sum of several diameter values by the total number of values.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>average diameter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1366
preferred name: average diameter
synonym: mean diameter

coat
type: Class
subclass of: fiat material part
subclass of: Restriction
  on property: has quality
  some values from: coat composition
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fiat material part which is a thin outer layer or film of material covering the surface of an object (e.g., a nanoparticle).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>coat</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1367
preferred name: coat
synonym: coating
synonym: surface coating

magnetic nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Class
    union of: Restriction
      on property: has component part
      some values from: Class
        intersection of: molecular entity
        intersection of: Restriction
    union of: Restriction
      on property: has property
      some values from: magnetic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has magnetic property.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>magnetic nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1370
preferred name: magnetic nanoparticle

silica nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: silicon dioxide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of silicon dioxide.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>silica nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1373
preferred name: silica nanoparticle
synonym: silicon dioxide nanoparticle

superparamagnetic iron oxide nanoparticle
type: Class
equivalent class: Class
  intersection of: iron oxide nanoparticle
  intersection of: Class
    union of: Restriction
      on property: has component part
      some values from: Class
        intersection of: iron oxide
        intersection of: Restriction
    union of: Restriction
      on property: has property
      some values from: superparamagnetic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iron oxide nanoparticle which has superparamagnetic property.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>superparamagnetic iron oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1374
synonym: SPIO nanoparticle
preferred name: superparamagnetic iron oxide nanoparticle

polymeric nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: polymer
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of polymer.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>polymeric nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1375
synonym: polymer nanoparticle
preferred name: polymeric nanoparticle

fluorescent
type: Class
subclass of: disposition
subclass of: Restriction
  on property: is realized in
  some values from: fluorescence
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition inhering in a bearer which emits light of longer wavelength during absorption of radiation of shorter (invisible) wavelength.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fluorescent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1376
DB xref ID: PATO:0000018
synonym: fluorescence property
preferred name: fluorescent

fluorescent nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Class
    union of: Restriction
      on property: has component part
      some values from: Class
        intersection of: molecular entity
        intersection of: Restriction
    union of: Restriction
      on property: has property
      some values from: fluorescent
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has fluorescence property.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fluorescent nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1377
preferred name: fluorescent nanoparticle

hydrogel nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: part of
    some values from: hydrogel
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which exists while dispersed in a hydrogel.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydrogel nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1378
preferred name: hydrogel nanoparticle

surface of nanoparticle
type: Class
subclass of: material boundary
subclass of: Restriction
  on property: has property
  some values from: zeta potential
subclass of: Restriction
  on property: part of
  some values from: nanoparticle
subclass of: Restriction
  on property: has quality
  some values from: electric charge
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The surface of a nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>surface of nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1379
synonym: nanoparticle surface
preferred name: surface of nanoparticle

encapsulation
type: Class
subclass of: linkage
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A linkage in which a molecular entity or nanostructure becomes enclosed due to non-covalent interactions, in a nanoparticle's material site that is fully bounded by the particle's constituting material.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>encapsulation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_138
preferred name: encapsulation

radioisotope
type: Class
subclass of: isotope
subclass of: Restriction
  on property: has property
  some values from: radioactive
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An isotope which releases radiation as it breaks down.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>radioisotope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C799
code: NPO_1380
preferred name: radioisotope
synonym: radionuclide

radioactivity
type: Class
subclass of: emission
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Emission of particles or electromagnetic radiation caused by the spontaneous disintegration of atoms of unstable nuclei in order to form atoms with stable nuclei.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>radioactivity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1382
synonym: radioactive decay
preferred name: radioactivity

radioactive
type: Class
subclass of: disposition
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition inhering in the bearer by virtue of it exhibiting or causing radioactivity.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>radioactive</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1383
DB xref ID: PATO:0001741
preferred name: radioactive

metal nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: metal
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of a metal.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>metal nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1384
preferred name: metal nanoparticle
synonym: metallic nanoparticle

immunoglobulin
type: Class
subclass of: antibody
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antibody which has molecular mass of 150-950 kDa, and consists of one or more basic units of four polypeptide chains comprising of two heavy chains and two light chains held together by disulphide links.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>immunoglobulin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: Ig
DB xref ID: NCIT:C572
code: NPO_1388
preferred name: immunoglobulin

immunoglobulin A
type: Class
subclass of: immunoglobulin isotype
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An immunoglobulin isotype which is associated with antibody-mediated mucosal immunity. It is secreted as dimers into the mucosa and is the most effective isotype at fixing complement by the alternative pathway, even though it lacks the ability to fix complement by the classical pathway. There are two subtypes in the human - IgA1 and IgA2. [Source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>immunoglobulin A</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: IgA
DB xref ID: NCIT:C565
code: NPO_1389
preferred name: immunoglobulin A

immunoglobulin D
type: Class
subclass of: immunoglobulin isotype
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An immunoglobulin isotype, which is expressed on naive B cells along with IgM.[Source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>immunoglobulin D</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: IgD
DB xref ID: NCIT:C566
code: NPO_1390
preferred name: immunoglobulin D

immunoglobulin E
type: Class
subclass of: immunoglobulin isotype
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An immunoglobulin isotype, which has the unique ability to bind with high affinity to IgE receptors (FceRI) on mast cells and basophils and induce degranulation and cytokine production by these cells when they are crosslinked by antigen. In addition to a central role in atopy and allergic responses, it has been speculated that IgE-mediated mast cell degranulation, by its release of mediators that increase vascular permeability, has an important role in the initiation of immune response in general. [Source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>immunoglobulin E</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: IgE
DB xref ID: NCIT:C567
code: NPO_1391
preferred name: immunoglobulin E

immunoglobulin G
type: Class
subclass of: immunoglobulin isotype
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An immunoglobulin isotype, which characterizes secondary immune responses. This isotype is further broken down into several smaller subclasses (IgG1, IgG2a, IgG2b, IgG3 in the mouse; IgG1-4 in the human), and each subclass is differentially synthesized and secreted into the serum upon differential immune stimuli.[Source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>immunoglobulin G</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: IgG
DB xref ID: NCIT:C568
code: NPO_1392
preferred name: immunoglobulin G

immunoglobulin M
type: Class
subclass of: immunoglobulin isotype
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A main immunoglobulin isotype which is secreted during a primary immune response. IgM binds with low affinity but high avidity (multiple binding sites) because it not only occurs as monomers but also as pentamers and hexamers.[Source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>immunoglobulin M</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: IgM
DB xref ID: NCIT:C569
code: NPO_1393
preferred name: immunoglobulin M

immunoglobulin isotype
type: Class
subclass of: immunoglobulin
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A class of immunoglobulins, which refers to genetic variations or differences in the constant region of the heavy chain of the Ig</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>immunoglobulin isotype</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1394
synonym: immunoglobulin class
preferred name: immunoglobulin isotype
synonym: isotype

targeting function
type: Class
subclass of: function
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A function which inheres in a material entity, and is realized in a process in which the material entity is used to target another material entity.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>targeting function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1395
preferred name: targeting function

imaging function
type: Class
subclass of: function
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A function inhering in a material entity by virtue of its use for imaging purposes.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>imaging function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1396
preferred name: imaging function

therapeutic function
type: Class
subclass of: function
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A function inhering in a material entity by virtue of its use for therapeutic purposes.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>therapeutic function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1397
preferred name: therapeutic function

acyl halide
type: Class
equivalent class: Restriction
  on property: has part
  some values from: acyl halide group
subclass of: acyl compound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acyl halide compound is an acyl compound which is characterized by the presence of acyl halide group. It has the structure R-(C=O)-X, where 'R' denotes an organic group and X denotes a halogen atom (F, Cl, Br or I).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>acyl halide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_140
synonym: acid halide
preferred name: acyl halide

bioluminescence
type: Class
subclass of: chemiluminescence
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Chemiluminescence produced by living systems.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>bioluminescence</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1403
preferred name: bioluminescence

nanoparticle sample
type: Class
subclass of: sample
subclass of: Restriction
  on property: part of
  some values from: nanoparticle formulation
subclass of: Restriction
  on property: has quality
  some values from: polydispersity
subclass of: Restriction
  on property: has component part
  some values from: Class
    union of: nanoparticle component
    union of: nanoparticle
subclass of: Restriction
  on property: has quality
  some values from: purity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A small representative portion of a nanoparticle formulation.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanoparticle sample</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1404
preferred name: nanoparticle sample

technique
type: Class
subclass of: procedure
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A systematic procedure or a practical method which is used for accomplishing a task.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1405
design note: [DGT, June 10, 2010]: Description for a specific type of technique could contain the following types of information: 1) principle used in the technique (e.g. NMR for NMR spectroscopy), 2) description of the principle if the term that describes the principle is not represented in the ontology, 3) tool used in a technique (e.g., scanning electron microscope in scanning electron microscopy), 4) applications of the technique, and 5) information on how to use the technique for each type of application.
preferred name: technique

procedure
type: Class
subclass of: process
subclass of: Restriction
  on property: has time period
  some values from: duration
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A temporal interval which is the time during which a process continues to occur.</ncicp:def-definition><ncicp:Definition_Review_Date>130524</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>procedure</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1406
synonym: method
preferred name: procedure

experiment
type: Class
subclass of: procedure
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A scientific procedure which is a process of conducting a test under controlled conditions to make a discovery, test a hypothesis, or demonstrate a known fact.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>experiment</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1407
preferred name: experiment

assay
type: Class
subclass of: experiment
subclass of: Restriction
  on property: uses reagent
  some values from: reagent
subclass of: Restriction
  on property: uses instrument
  some values from: instrument
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An experiment which is used to 1) analyze or measure (qualitatively/quantitatively) the composition and property of a substance; or, 2) to analyze a process or activity.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1408
preferred name: assay

in vitro assay
type: Class
subclass of: bioassay
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A bioassay conducted in an artificial environment (e.g., test tube) outside the body of a living organism, under controlled conditions.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>in vitro assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C15958
code: NPO_1409
preferred name: in vitro assay
synonym: in vitro bioassay

thioether group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: thioether
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -S-. The group is characteristic of thioether wherein the sulfur atom is attached to two carbon atoms via single covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thioether group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_141
preferred name: thioether group

in vivo assay
type: Class
subclass of: bioassay
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A bioassay conducted inside the body of a living organism.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>in vivo assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1410
preferred name: in vivo assay
synonym: in vivo bioassay

bioassay
type: Class
subclass of: assay
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An assay which is used to test or analyse the biological activity of a substance, and which is performed by studying its effect on an organism or in a test tube under controlled conditions.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>bioassay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1411
preferred name: bioassay

physical assay
type: Class
subclass of: assay
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An assay for evaluating the physical properties of a sample.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>physical assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1412
preferred name: physical assay

nanoparticle characterization
type: Class
subclass of: characterization
subclass of: Restriction
  on property: has part
  some values from: in vitro characterization
subclass of: Restriction
  on property: has part
  some values from: in vivo characterization
subclass of: Restriction
  on property: has part
  some values from: physicochemical characterization
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Characterization of nanoparticles or nanoparticle formulations.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanoparticle characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1413
synonym: characterization of nanoparticle
preferred name: nanoparticle characterization

emulsifier
type: Class
equivalent class: Class
  intersection of: compound for material synthesis
  intersection of: Restriction
    on property: has role
    some values from: emulsifying role
subclass of: Restriction
  on property: agent in
  some values from: emulsification
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule used for stabilizing an emulsion.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>emulsifier</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1414
preferred name: emulsifier
synonym: emulsifying agent

microscopy
type: Class
subclass of: technique
subclass of: Restriction
  on property: uses instrument
  some values from: microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A technique which uses a microscope to study a material object or a process that cannot be seen by the naked eye.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1415
preferred name: microscopy
synonym: microscopy technique

separation technique
type: Class
subclass of: technique
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A technique which is used to separate substances from mixtures.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>separation technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1416
synonym: separation method
preferred name: separation technique

centrifugation
type: Class
subclass of: separation technique
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A separation technique which uses a centrifuge to generate a centrifugal force for separating fluids of different densities from mixtures or for separating liquids from solids.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>centrifugation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1417
preferred name: centrifugation

electrophoresis
type: Class
subclass of: separation technique
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A separation technique used for separating charged particles in a fluid or gel under the action of an electric field. The electric field causes the movement of charged particles.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>electrophoresis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1418
preferred name: electrophoresis

gel electrophoresis
type: Class
subclass of: electrophoresis
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Electrophoresis method used for separating molecules of proteins and nucleic acids from a sample mixture of similar molecules through a gelatinous matrix. Subject to an electric field, each molecule in the sample mixture migrates through the matrix at a different rate, depending mainly on electrical charge and size, resulting in spatial separation within the matrix of each molecular species in the sample mixture. Agarose and acrylamide in a cylindrical tube or slab gel are commonly used media for electrophoresis of proteins and nucleic acids.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gel electrophoresis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C18091
code: NPO_1419
preferred name: gel electrophoresis

agarose gel electrophoresis
type: Class
subclass of: gel electrophoresis
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Gel electrophoresis in which highly purified agar is used as the diffusion medium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>agarose gel electrophoresis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C16537
code: NPO_1420
preferred name: agarose gel electrophoresis

polyacrylamide gel electrophoresis
type: Class
subclass of: gel electrophoresis
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Gel electrophoresis technique in which a polyacrylamide gel is used as the diffusion medium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>polyacrylamide gel electrophoresis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C16539
code: NPO_1421
preferred name: polyacrylamide gel electrophoresis

analysis
type: Class
subclass of: study
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process of examining the component parts of a whole and their relations in making up the whole [source: WordNet]. e.g., the identification and measurement of chemical constituents of a substance or specimen.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>analysis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1422
preferred name: analysis

protein analysis
type: Class
subclass of: analysis
subclass of: Restriction
  on property: has part
  some values from: detection of proteins
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Analysis of protein components in a sample.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>protein analysis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1423
synonym: analysis of proteins
preferred name: protein analysis

western blot analysis
type: Class
subclass of: technique
subclass of: Restriction
  on property: technique used for
  some values from: detection of proteins
subclass of: Restriction
  on property: has part
  some values from: gel electrophoresis
subclass of: Restriction
  on property: has participant
  some values from: antibody
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A technique which is used for the detection or identification of proteins or peptides that have been separated by gel electrophoresis and transferred onto nitrocellulose or other type of paper or nylon membrane. The proteins are then detected by reaction with enzymatically labeled or radiolabeled antibody probes.</ncicp:def-definition><ncicp:Definition_Review_Date>100614</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>western blot analysis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C16357
code: NPO_1424
synonym: western blot
preferred name: western blot analysis
synonym: western blotting
synonym: western blotting technique

detection
type: Class
subclass of: process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process or action of identifying the presence of something.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>detection</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1425
preferred name: detection

detection of proteins
type: Class
subclass of: detection
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Detection of proteins or a protein components in a sample.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>detection of proteins</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1426
preferred name: detection of proteins
synonym: protein detection

SDS polyacrylamide gel electrophoresis
type: Class
subclass of: polyacrylamide gel electrophoresis
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polyacrylamide gel electrophoresis technique for separating proteins in a sample which is prepared with sodium dodecyl sulfate (SDS) as a buffer that maintains the proteins in their denatured states.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>SDS polyacrylamide gel electrophoresis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1427
preferred name: SDS polyacrylamide gel electrophoresis
synonym: SDS-PAGE
synonym: sodium dodecyl sulfate - polyacrylamide gel electrophoresis

electron microscopy
type: Class
subclass of: microscopy
subclass of: Restriction
  on property: uses instrument
  some values from: electron microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A microscopy technique based on the use of electron microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>electron microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1428
preferred name: electron microscopy

scanning electron microscopy
type: Class
subclass of: electron microscopy
subclass of: Restriction
  on property: uses instrument
  some values from: scanning electron microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electron microscopy technique based on the use of scanning electron microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>scanning electron microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1429
synonym: SEM technique
preferred name: scanning electron microscopy

transmission electron microscopy
type: Class
subclass of: electron microscopy
subclass of: Restriction
  on property: uses instrument
  some values from: transmission electron microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electron microscopy technique based on the use of transmission electron microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>transmission electron microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: A light source at the top of the TEM emits the electrons that travel through vacuum in the column of the microscope. Instead of glass lenses focusing the light in the light microscope, the TEM uses electromagnetic lenses to focus the electrons into a very thin beam. The electron beam then travels through the specimen you want to study. Depending on the density of the material present, some of the electrons are scattered and disappear from the beam. At the bottom of the microscope the unscattered electrons hit a fluorescent screen, which gives rise to a shadow image of the specimen with its different parts displayed in varied darkness according to their density. The image can be studied directly by the operator or photographed with a camera. [source: http://Nobelprize.org]
code: NPO_1430
synonym: TEM technique
preferred name: transmission electron microscopy

optical microscopy
type: Class
subclass of: microscopy
subclass of: Restriction
  on property: uses instrument
  some values from: optical microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A microscopy technique based on the use of optical microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>optical microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1431
synonym: light microscopy
preferred name: optical microscopy

fluorescence microscopy
type: Class
subclass of: optical microscopy
subclass of: Restriction
  on property: has part
  some values from: Class
    union of: fluorescence
    union of: phosphorescence
subclass of: Restriction
  on property: uses instrument
  some values from: fluorescence microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An optical microscopy technique based on the use of fluorescence microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fluorescence microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1432
preferred name: fluorescence microscopy

scanning probe microscopy
type: Class
subclass of: microscopy
subclass of: Restriction
  on property: uses instrument
  some values from: scanning probe microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A microscopy technique based on the use of scanning probe microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>scanning probe microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C20346
code: NPO_1433
preferred name: scanning probe microscopy

atomic force microscopy
type: Class
subclass of: scanning probe microscopy
subclass of: Restriction
  on property: uses instrument
  some values from: atomic force microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A scanning probe microscopy technique based on the use of atomic force microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>atomic force microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1434
preferred name: atomic force microscopy
synonym: scanning force microscopy

scanning tunneling microscopy
type: Class
subclass of: scanning probe microscopy
subclass of: Restriction
  on property: uses instrument
  some values from: scanning tunneling microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A scanning probe microscopy technique based on the use of scanning tunneling microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>scanning tunneling microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1435
preferred name: scanning tunneling microscopy

instrument
type: Class
subclass of: material entity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A device or tool that requires skill for proper use, and it is intended for a purpose.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>instrument</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1436
synonym: equipment
preferred name: instrument

microscope
type: Class
subclass of: instrument
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An instrument which is used for magnifying and viewing images of objects that are too small to be seen by the naked or unaided eye. [source:http://encyclopedia.thefreedictionary.com/microscope]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C20677
code: NPO_1437
preferred name: microscope

electron microscope
type: Class
subclass of: microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A microscope that is similar in purpose to a light microscope but achieves much greater resolving power by using a parallel beam of electrons to illuminate the object instead of a beam of light. [source:WordNet 3.0]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>electron microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: Electron Microscopes(EMs) function exactly as their optical counterparts except that they use a focused beam of electrons instead of light to "image" the specimen and gain information as to its structure and composition. The basic steps involved in all EMs: 1. A stream of electrons is formed (by the Electron Source) and accelerated toward the specimen using a positive electrical potential 2. This stream is confined and focused using metal apertures and magnetic lenses into a thin, focused, monochromatic beam. 3. This beam is focused onto the sample using a magnetic lens 4. Interactions occur inside the irradiated sample, affecting the electron beam These interactions and effects are detected and transformed into an image The above steps are carried out in all EMs regardless of type. [source: http://unl.edu/CMRAcfem/em.htm]
DB xref ID: NCIT:C28219
code: NPO_1438
preferred name: electron microscope

optical microscope
type: Class
subclass of: microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A microscope which uses visible light and a system of lenses to magnify images of small objects.[source: http://encyclopedia.thefreedictionary.com]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>optical microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C28265
code: NPO_1439
synonym: light microscope
preferred name: optical microscope

iodine atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 53
disjoint with: manganese atom
disjoint with: sodium atom
disjoint with: lanthanum atom
disjoint with: francium atom
disjoint with: caesium atom
disjoint with: nickel atom
disjoint with: fluorine atom
disjoint with: niobium atom
disjoint with: neon atom
disjoint with: promethium atom
disjoint with: mercury atom
disjoint with: zinc atom
disjoint with: potassium atom
disjoint with: neptunium atom
disjoint with: chlorine atom
disjoint with: dubnium atom
disjoint with: radium atom
disjoint with: uranium atom
disjoint with: zirconium atom
disjoint with: rubidium atom
disjoint with: osmium atom
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom

scanning electron microscope
type: Class
subclass of: electron microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electron microscope which scans the surface of a sample with a beam of electrons and detects the interaction of the electrons with the atoms on the surface to produce a topographical image of the sample.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>scanning electron microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C78814
code: NPO_1440
synonym: SEM
preferred name: scanning electron microscope

transmission electron microscope
type: Class
subclass of: electron microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electron microscope which transmits a beam of electrons through a finely sliced section of a specimen/sample and creates an image of the specimen/sample based on its effect on the phase of the electrons that pass through.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>transmission electron microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C78813
code: NPO_1441
synonym: TEM
comment: TEMs use electrons as light source and their much lower wavelength makes it possible to get a resolution a thousand times better than with a light microscope.[source: http://Nobelprize.org]
preferred name: transmission electron microscope

scanning probe microscope
type: Class
subclass of: microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A microscope which forms images of surfaces using a physical probe that scans the specimen and records the probe-surface interaction as a function of position.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>scanning probe microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C78803
code: NPO_1442
synonym: SPM
preferred name: scanning probe microscope

fluorescence microscope
type: Class
subclass of: optical microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An optical microscope which is used to study the properties of a specimen or sample based on the phenomena of fluorescence and phosphorescence. The microscope has a filter which allows radiation of a specific wavelength of light to pass through.The specimen or the sample contains components labeled with a fluorescent molecule which absorbs this light, and then emits light of a longer wavelength. A second filter of the microscope separates the emitted light from the brighter excitation light (shorter wavelength). As a result, the fluorescing regions of the sample shine out against a dark background with high contrast, when observed through the microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fluorescence microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1443
comment: [definition: adapted from http://nobelprize.org; http://en.wikipedia.org/wiki/Fluorescence_microscope ]
preferred name: fluorescence microscope

atomic force microscope
type: Class
subclass of: scanning probe microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A scanning probe microscope which consists of a microscale cantilever with a sharp tip (probe) at its end that is used to scan the specimen surface. The probe is extremely close to - but does not touch-the surface. As the probe traverses the surface, attractive and repulsive forces arising between it and the atoms on the surface induce forces on the probe that bend the cantilever. The amount of bending is measured and recorded, providing a map of the atoms on the surface. Atomic force microscopes can achieve magnification of a factor of 5 × 10^6, with a resolution of 2 angstroms, sufficient to resolve individual carbon atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>atomic force microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: AFM
DB xref ID: NCIT:C78804
code: NPO_1445
synonym: SFM
comment: [definition: adapted from NCIT, http://www.thefreedictionary.com, http://en.wikipedia.org]
preferred name: atomic force microscope
synonym: scanning force microscope

scanning tunneling microscope
type: Class
subclass of: scanning probe microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A scanning probe microscope which consists of a probe with a small voltage applied to it ending in a tiny sharp electrically conducting tip (ideally consisting of one atom) that is moved close the material's surface. It scans the surface of a sample with a beam of electrons, causing a narrow channel of tunneling electrons to flow between the sample and the beam, and producing three-dimensional images of atomic topography and structure.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>scanning tunneling microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C17374
code: NPO_1446
synonym: STM
comment: [definition: adapted from http://www.thefreedictionary.com]
preferred name: scanning tunneling microscope

magnetic force microscope
type: Class
subclass of: scanning probe microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A scanning probe microscope which is derived from atomic force microscope, having a magnetized tip that map the spatial distribution of magnetism by measuring the magnetic interactions between the sample and the tip. It is used to study magnetic materials.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>magnetic force microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: MFM
code: NPO_1447
comment: [definition: adapted from http://encyclopedia.thefreedictionary.com]
preferred name: magnetic force microscope

doxorubicin-loaded nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: Class
      intersection of: doxorubicin
      intersection of: Restriction
        on property: has role
        some values from: payload agent role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is loaded with doxorubicin.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>doxorubicin-loaded nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_145
synonym: adriamycin-loaded nanoparticle
preferred name: doxorubicin-loaded nanoparticle

high resolution transmission electron microscopy
type: Class
subclass of: transmission electron microscopy
subclass of: Restriction
  on property: uses instrument
  some values from: high resolution transmission electron microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A transmission electron microscopy technique based on the use of high resolution transmission electron microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>high resolution transmission electron microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1451
preferred name: high resolution transmission electron microscopy

high resolution transmission electron microscope
type: Class
subclass of: transmission electron microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A transmission electron microscope which operates at an imaging mode that allows the imaging of the crystallographic structure of a sample at an atomic scale. In this mode, the transmitted and the diffracted beams of electrons are allowed to interfere to produce phase-contrast images.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>high resolution transmission electron microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: HRTEM
code: NPO_1452
comment: [definition source]: http://en.wikipedia.org
preferred name: high resolution transmission electron microscope

scanning transmission electron microscope
type: Class
subclass of: transmission electron microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A transmission electron microscope with which a beam of electrons pass through the specimen, where the beam is focused into a narrow spot that is scanned over the sample specimen in a raster.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>scanning transmission electron microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1453
synonym: STEM
preferred name: scanning transmission electron microscope

scanning transmission electron microscopy
type: Class
subclass of: transmission electron microscopy
subclass of: Restriction
  on property: uses instrument
  some values from: scanning transmission electron microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A transmission electron microscopy technique based on the use of scanning transmission electron microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>scanning transmission electron microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1454
preferred name: scanning transmission electron microscopy

differential interference contrast microscope
type: Class
subclass of: optical microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An optical microscope which generates contrast within the specimen by exploiting phase differences between a specimen (sample) light ray and a reference ray. The sample and reference rays are created after the ray traverses, and is phase-distorted by, the sample. The phased ray then is split into two equally phased, but spatially separated ("sheared") rays by the action of a Wollaston prism. Finally, the ray-pairs pass through a polarizing filter where they are vibrationally recombined and interact at the image plane. It is the wave interference of these two rays that creates contrast.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>differential interference contrast microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: DIC microscope
comment: DIC microscope is based on interferometry, which is the technique of superposing (interfering) two or more waves, to detect differences between them. In interferometry, a single ray of light is split into two rays, one traversing and the other missing the specimen but interacting with the background. The rays are then recombined at the image plane, where wave interference may occur. Image contrast can be modified by altering the phase difference between the reference and specimen rays. [source: http://encyclopedia.thefreedictionary.com]
code: NPO_1455
preferred name: differential interference contrast microscope

differential interference contrast microscopy
type: Class
subclass of: optical microscopy
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An optical microscopy based on the use of differential interference contrast microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>differential interference contrast microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1456
preferred name: differential interference contrast microscopy

nanoparticle response to external stimulus
type: Class
subclass of: nanoparticle response to stimulus
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to stimulus, which occurs in response to the external stimulus acting on the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanoparticle response to external stimulus</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_146
preferred name: nanoparticle response to external stimulus

flow cytometry
type: Class
subclass of: technique
subclass of: Restriction
  on property: uses instrument
  some values from: flow cytometer
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A technique for counting, examining and sorting microscopic particles (e.g., single cells) suspended in a stream of fluid that passes through a beam of light. It allows for multiple analyses of the physical and chemical characteristics of single cells flowing through an optical and/or electrical detection apparatus.</ncicp:def-definition><ncicp:Definition_Review_Date>100617</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>flow cytometry</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C16585
code: NPO_1465
comment: [definition: adapted from NCIT, http://encyclopedia.thefreedictionary.com]
preferred name: flow cytometry

phase analysis light scattering
type: Class
subclass of: light scattering
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A light scattering technique for measuring the electrophoretic mobilities of charged particles suspended in nonpolar media (i.e. solvents with much lower relative permittivities than water).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>phase analysis light scattering</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1467
synonym: PALS
comment: [definition: adapted from http://www.unisa.edu.au/laser/Research/PALS.asp]
preferred name: phase analysis light scattering

spectroscopy
type: Class
subclass of: technique
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A technique which is used for measuring the intensity of electromagnetic radiation that is absorbed, emitted (radiated), or scattered at different wavelengths or frequencies by a molecular entity or substance. This technique is used in studying the interaction of electromagnetic radiation with matter.</ncicp:def-definition><ncicp:Definition_Review_Date>100611</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C17155
code: NPO_1468
synonym: spectroscopic technique
preferred name: spectroscopy

dynamic light scattering
type: Class
subclass of: light scattering spectroscopy
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A spectroscopic technique which utilizes a laser beam to irradiate a sample containing particles in suspension, resulting in light scattering.When the scattered light is collected over a small solid angle, the light will exhibit intensity fluctuations. This is because the Brownian motion of the scatterers causes the phase of the light scattered from each particle to change with time, hence the total scattered intensity also fluctuates with time. The rapid fluctuations in scattering intensity, collected around a mean value at a certain angle, will depend on the particle diffusion and on the particle size. For a given temperature and viscosity, a calculated correlation function yields a diffusion coefficient, which can be used to calculate particle size.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dynamic light scattering</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: DLS
DB xref ID: NCIT:C62329
code: NPO_1469
synonym: PCS
synonym: QELS
synonym: Quasi-Elastic Light Scattering
comment: [definition source: NCI]
preferred name: dynamic light scattering
synonym: photon correlation spectroscopy

compound or molecule
type: Class
subclass of: pure substance
subclass of: Restriction
  on property: has quality
  some values from: molecular structure
subclass of: Restriction
  on property: has quality
  some values from: molecular weight
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A pure substance which is made up of more than one type of atom, and can be decomposed into its elements by chemical methods. This class includes terms that can be used to describe molecules or compounds. A molecule is a group of atoms bonded together, representing the smallest fundamental unit of a chemical compound that can take part in a chemical reaction.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>compound or molecule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_147
preferred name: compound or molecule

nuclear magnetic resonance spectroscopy
type: Class
subclass of: absorption spectroscopy
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An absorption spectroscopic technique which uses NMR (nuclear magnetic resonance) to basically measure the frequency (resonant frequency) of vibrating nuclei (having non-zero spin) of a given type in the presence of a magnetic field. When placed in a magnetic field, nuclei that have non-zero spins absorb frequency characteristic of the isotope. The frequency (resonant frequency), the energy of absorption, and the intensity of measured NMR signal are proportional to the strength of the magnetic field. Nuclei of different isotopes in a substance resonate at different frequencies depending upon the local molecular geometry (bond lengths, bond angles, bonded atoms, etc.) and the local magnetic field at each nucleus. Nuclei of the same type can have slightly different resonant frequencies depending on the chemical environment. The difference between the frequency of the measured signal (NMR signal) from nuclei (in a molecule) in one sample and that (reference resonant frequency) from the same type of nuclei in a reference substance is used to obtain structural information of the molecule in a sample, or the chemical composition of the sample. This technique has applications in the study of the physical, chemical, and biological properties of matter.</ncicp:def-definition><ncicp:Definition_Review_Date>100610</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.answers.com/topic/nmr-spectroscopy (June 10, 2010), http://www.cis.rit.edu/htbooks/nmr/inside.htm (June 10, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nuclear magnetic resonance spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: Depending on the local chemical environment, different protons in a molecule resonate at slightly different frequencies. Since this frequency shift is proportional to the strength of the magnetic field, it is converted into a field-independent dimensionless value known as the chemical shift. The chemical shift is reported as a relative measure from some reference resonance frequency. (For the nuclei1H, 13C, and 29Si, TMS (tetramethylsilane) is commonly used as a reference.) This difference between the frequency of the signal and the frequency of the reference is divided by frequency of the reference signal to give the chemical shift. The frequency shifts are extremely small in comparison to the fundamental NMR frequency. A typical frequency shift might be 100 Hz, compared to a fundamental NMR frequency of 100 MHz, so the chemical shift is generally expressed in parts per million (ppm). By understanding different chemical environments, the chemical shift can be used to obtain some structural information about the molecule in a sample. The conversion of the raw data to this information is called assigning the spectrum. [source: http://encyclopedia.thefreedictionary.com]
DB xref ID: NCIT:C16810
synonym: NMR spectroscopy
code: NPO_1470
comment: When placed in a magnetic field, NMR active nuclei (such as 1H or 13C) absorb at a frequency characteristic of the isotope. The resonant frequency, energy of the absorption and the intensity of the signal are proportional to the strength of the magnetic field.
synonym: magnetic resonance spectroscopy
preferred name: nuclear magnetic resonance spectroscopy

fluorescence spectroscopy
type: Class
subclass of: emission spectroscopy
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which analyzes fluorescence spectra from a sample. It involves using a beam of light, usually ultraviolet light, that excites the electrons in molecules of certain compounds and causes them to emit light of a lower energy, typically, but not necessarily, visible light.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fluorescence spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C17738
code: NPO_1476
preferred name: fluorescence spectroscopy
synonym: fluorometry
synonym: spectrofluorometry

imaging technique
type: Class
subclass of: technique
subclass of: Restriction
  on property: technique used for
  some values from: imaging
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A technique to obtain the image (appearance or form) of the whole or part of a material object.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>imaging technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C17369
code: NPO_1477
synonym: imaging method
preferred name: imaging technique

diagnostic imaging
type: Class
subclass of: imaging
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Imaging of structural or functional patterns of organs or tissues for the purpose of diagnostic evaluation.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>diagnostic imaging</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C16502
code: NPO_1478
preferred name: diagnostic imaging

tomography
type: Class
subclass of: imaging technique
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imaging technique in which waves of energy are passed through the sections of a solid object to obtain images of the internal structures of the object.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tomography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1479
preferred name: tomography

non-ionizable
type: Class
subclass of: ionizability
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A qualitative measure of "ionizability" which indicates that the bearer cannot be ionized to gain negative or positive charges.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>non-ionizable</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_148
preferred name: non-ionizable

computed tomography
type: Class
subclass of: tomography
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A medical tomographic technique which uses computer to construct a three-dimensional image of the internal structures of an object from a large series of two-dimensional cross-sectional X-ray images of the object, taken around a single axis of rotation.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>computed tomography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: CT
DB xref ID: NCIT:C17204
code: NPO_1480
preferred name: computed tomography

single photon emission computed tomography
type: Class
subclass of: tomography
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A tomographic technique which uses radionuclides that emit single photons in the gamma energy range. The radionuclides are administered into a patient's body and the gamma rays produced by these radionuclides pass through the patient's body, which are then detected by one or more gamma cameras rotated around the patient's body. Series of two-dimensional cross-sectional images of the body, produced by this technique, can be used to create three-dimensional images by computer reconstruction.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>single photon emission computed tomography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C17203
code: NPO_1481
synonym: SPECT
preferred name: single photon emission computed tomography

positron emission tomography
type: Class
subclass of: tomography
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A tomography technique for measuring the gamma radiation produced by collisions of electrons and positrons (anti-electrons) within living tissue. In positron emission tomography (PET), a subject is given a dose of a positron-emitting radionuclide attached to a metabolically active substance (for example, 2-fluoro-2-deoxy-D-glucose (FDG), which is similar to a naturally occurring sugar, glucose, with the addition of a radioactive fluorine atom). When living tissue containing the positron emitter is bombarded by electrons, gamma radiation produced by collisions of electrons and positrons is detected by a scanner, revealing in fine detail the tissue location of the metabolically-active substance administered.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>positron emission tomography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C17007
code: NPO_1482
synonym: PET
comment: [definition source: NCI]
preferred name: positron emission tomography

magnetic resonance imaging
type: Class
subclass of: imaging technique
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A non-invasive imaging method of creating images of internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>magnetic resonance imaging</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: MRI
DB xref ID: MeSH:D008279
DB xref ID: NCIT:C16809
code: NPO_1483
comment: [definition: adapted from MeSH]
preferred name: magnetic resonance imaging

ultrasound imaging
type: Class
subclass of: imaging technique
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imaging technique in which ultrasound (sound waves with frequency above the human hearing range) waves are bounced off tissues and the echoes produce a picture (sonogram).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ultrasound imaging</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C17230
code: NPO_1484
preferred name: ultrasound imaging

titanium dioxide
type: Class
subclass of: oxide
subclass of: Restriction
  on property: has quality
  some values from: inorganic
subclass of: Restriction
  on property: has part
  some values from: titanium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of titanium consisting of two oxygen atoms bonded to one titanium atom via double bonds.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>titanium dioxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1485
synonym: TiO2
preferred name: titanium dioxide
synonym: titanium oxide
synonym: titanium(IV) oxide

titanium oxide nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: titanium dioxide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle, which is basically composed of titanium dioxide.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>titanium oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1486
synonym: TiO2 nanoparticle
preferred name: titanium oxide nanoparticle

sample
type: Class
equivalent class: Restriction
  on property: has quality
  some values from: sample composition
subclass of: fiat material part
subclass of: Restriction
  on property: has quality
  some values from: physical state
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A substance which is a small representative portion of a whole material entity.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>sample</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1487
preferred name: sample

sample composition
type: Class
equivalent class: Class
  intersection of: chemical composition
  intersection of: Restriction
    on property: quality of
    some values from: sample
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Chemical composition of a sample determined by the type and amount of the chemical components of a sample.</ncicp:def-definition><ncicp:Definition_Review_Date>100727</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>sample composition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1488
preferred name: sample composition

sample preparation
type: Class
subclass of: process
subclass of: Restriction
  on property: has part
  some values from: synthesis part
subclass of: Restriction
  on property: uses technique
  some values from: material synthesis technique
subclass of: Restriction
  on property: has output participant
  some values from: sample
subclass of: Restriction
  on property: part of
  some values from: study
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A process which is the synthesis or preparation of a sample for analysis, testing or characterization.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>sample preparation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1489
preferred name: sample preparation

covalent interaction
type: Class
subclass of: intramolecular interaction
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An intramolecular interaction in which two atoms share one or more electron pairs.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>covalent interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_149
synonym: covalent bonding
preferred name: covalent interaction

nanoparticle property
type: Class
equivalent class: Class
  intersection of: specifically_dependent_continuant
  intersection of: Restriction
    on property: inheres in
    some values from: Class
      union of: nanoparticle component
      union of: nanoparticle
      union of: nanoparticle formulation
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A property which inheres in or borne by a nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanoparticle property</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1490
preferred name: nanoparticle property
synonym: property of nanoparticle

molecular component in nanoparticle formulation
type: Class
equivalent class: Class
  intersection of: chemical component in nanoparticle formulation
  intersection of: Restriction
    on property: has identification type
    some values from: molecular entity
subclass of: Restriction
  on property: has identification type
  all values from: molecular entity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component which is identified by virtue of its molecular structure in a nanoparticle formulation.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>molecular component in nanoparticle formulation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1491
preferred name: molecular component in nanoparticle formulation

functionalizing role
type: Class
subclass of: component role in nanoparticle
subclass of: Restriction
  on property: role of
  some values from: functionalizing agent
subclass of: Restriction
  on property: is realized in
  some values from: functionalization of nanoparticle
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A role which inheres in a material entity by virtue of its ability to add/modify the properties or functions of another material entity by being associated to the latter.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>functionalizing role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1492
preferred name: functionalizing role

functionalizing agent
type: Class
equivalent class: Class
  intersection of: chemical component in nanoparticle formulation
  intersection of: Restriction
    on property: has role
    some values from: functionalizing role
subclass of: Restriction
  on property: participates in
  some values from: functionalization of nanoparticle
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component in a nanoparticle formulation which adds/modifies functional properties or function of a nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>functionalizing agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1493
preferred name: functionalizing agent

chemical component in nanoparticle formulation
type: Class
equivalent class: Class
  intersection of: chemical component
  intersection of: Restriction
    on property: part of
    some values from: nanoparticle formulation
subclass of: Restriction
  on property: part of
  all values from: nanoparticle formulation
subclass of: Restriction
  on property: has property
  some values from: specifically_dependent_continuant
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component which is identified as part of a nanoparticle formulation.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>chemical component in nanoparticle formulation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1494
preferred name: chemical component in nanoparticle formulation

molecular component in nanoparticle
type: Class
equivalent class: Class
  intersection of: molecular component in nanoparticle formulation
  intersection of: Restriction
    on property: part of
    all values from: nanoparticle component
subclass of: Restriction
  on property: part of
  some values from: nanoparticle component
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component which is identified by virtue of its molecular structure that forms part of the basic chemical make up of a nanoparticle in a nanoparticle formulation.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>molecular component in nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1495
preferred name: molecular component in nanoparticle

nanoparticle component
type: Class
equivalent class: Class
  intersection of: chemical component in nanoparticle formulation
  intersection of: Restriction
    on property: has identification type
    some values from: nanoparticle
subclass of: Restriction
  on property: has encapsulated component part
  all values from: Class
    union of: molecular component in nanoparticle
    union of: nanoparticle component
subclass of: Restriction
  on property: has identification type
  all values from: nanoparticle
subclass of: Restriction
  on property: has quality
  some values from: particle concentration
subclass of: Restriction
  on property: has entrapped component part
  all values from: Class
    union of: molecular component in nanoparticle
    union of: nanoparticle component
subclass of: Restriction
  on property: has component part
  some values from: molecular component in nanoparticle
subclass of: Restriction
  on property: has conjugated component part
  all values from: molecular component in nanoparticle
subclass of: Restriction
  on property: has component part
  all values from: molecular component in nanoparticle
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component which is identified as a nanoparticle based on its structure, chemical composition or function.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanoparticle component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1496
preferred name: nanoparticle component

chemical component
type: Class
subclass of: fiat material part
subclass of: Restriction
  on property: has quality
  some values from: chemical composition
subclass of: Restriction
  on property: has quality
  some values from: Class
    union of: concentration
    union of: amount of substance
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fiat material part identified as being the chemical make up of a material entity.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>chemical component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1497
preferred name: chemical component

monomer
type: Class
subclass of: organic compound or molecule
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A small organic molecule which is bonded to other similar molecules to form a polymer.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>monomer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1498
preferred name: monomer

repeat unit
type: Class
subclass of: fiat material part
subclass of: Restriction
  on property: part of
  some values from: polymer
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component which occurs as repeated units linked together in a polymer chain.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>repeat unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1499
preferred name: repeat unit

iridium
type: Class
subclass of: element
disjoint with: californium
disjoint with: rhodium
disjoint with: germanium
disjoint with: mendelevium
disjoint with: iodine
disjoint with: nitrogen
disjoint with: meitnerium
disjoint with: lawrencium
disjoint with: einsteinium
disjoint with: beryllium
disjoint with: mercury
disjoint with: boron
disjoint with: dysprosium
disjoint with: radon
disjoint with: magnesium
disjoint with: calcium
disjoint with: protactinium
disjoint with: fluorine
disjoint with: neodymium
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt

chemical substance by physical state
type: Class
equivalent class: Class
  intersection of: chemical substance
  intersection of: Restriction
    on property: has quality
    some values from: physical state
subclass of: Restriction
  on property: has quality
  some values from: chemical composition
subclass of: Restriction
  on property: has quality
  some values from: amount of substance
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material entity which exists in some physical state that is identifiable as a whole at continuum length scales.</ncicp:def-definition><ncicp:Definition_Review_Date>100727</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>substance</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C45306
code: NPO_1500
preferred name: chemical substance by physical state

fluid state
type: Class
subclass of: physical state
subclass of: Restriction
  on property: quality of
  some values from: fluid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a fluid.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fluid state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1501
preferred name: fluid state

gaseous state
type: Class
subclass of: fluid state
subclass of: Restriction
  on property: quality of
  some values from: gas
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a gas.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gaseous state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1502
preferred name: gaseous state

vapor state
type: Class
subclass of: gaseous state
subclass of: Restriction
  on property: quality of
  some values from: vapor
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a vapor.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>vapor state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1503
preferred name: vapor state

liquid state
type: Class
subclass of: fluid state
subclass of: Restriction
  on property: quality of
  some values from: liquid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a liquid.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>liquid state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1504
preferred name: liquid state

state of mixture
type: Class
subclass of: physical state
subclass of: Restriction
  on property: quality of
  some values from: mixture
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a mixture.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>state of mixture</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1505
preferred name: state of mixture

state of suspension
type: Class
subclass of: state of mixture
subclass of: Restriction
  on property: quality of
  some values from: suspension
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a suspension.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>state of suspension</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1506
preferred name: state of suspension

colloidal state
type: Class
subclass of: state of suspension
subclass of: Restriction
  on property: quality of
  some values from: colloid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a colloid.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>colloidal state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1507
preferred name: colloidal state

state of emulsion
type: Class
subclass of: colloidal state
subclass of: Restriction
  on property: quality of
  some values from: emulsion
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of an emulsion.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>state of emulsion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1508
preferred name: state of emulsion

gel state
type: Class
subclass of: colloidal state
subclass of: Restriction
  on property: quality of
  some values from: gel
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a gel.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gel state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1509
preferred name: gel state

californium
type: Class
subclass of: element
disjoint with: rhodium
disjoint with: germanium
disjoint with: mendelevium
disjoint with: iodine
disjoint with: nitrogen
disjoint with: meitnerium
disjoint with: lawrencium
disjoint with: einsteinium
disjoint with: beryllium
disjoint with: mercury
disjoint with: boron
disjoint with: dysprosium
disjoint with: radon
disjoint with: magnesium
disjoint with: calcium
disjoint with: protactinium
disjoint with: fluorine
disjoint with: neodymium
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur

state of sol
type: Class
subclass of: colloidal state
subclass of: Restriction
  on property: quality of
  some values from: sol
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a sol.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>state of sol</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1510
preferred name: state of sol

solid state
type: Class
subclass of: physical state
subclass of: Restriction
  on property: quality of
  some values from: solid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a sold.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>solid state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1511
preferred name: solid state

crystalline state
type: Class
subclass of: solid state
subclass of: Restriction
  on property: quality of
  some values from: crystal
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a crystal.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>crystalline state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1512
preferred name: crystalline state

glassy state
type: Class
subclass of: solid state
subclass of: Restriction
  on property: quality of
  some values from: glass
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a glass.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>glassy state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1513
preferred name: glassy state

granular state
type: Class
subclass of: solid state
subclass of: Restriction
  on property: quality of
  some values from: granule
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a granule.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>granular state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1514
preferred name: granular state

powdered state
type: Class
subclass of: solid state
subclass of: Restriction
  on property: quality of
  some values from: powder
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a powder.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>powdered state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1515
preferred name: powdered state

imaging
type: Class
subclass of: process
subclass of: Restriction
  on property: uses technique
  some values from: imaging technique
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process of capturing, storing, manipulating, and displaying of images.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>imaging</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1516
preferred name: imaging

study
type: Class
subclass of: process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process which is a detailed examination, analysis, or critical inspection of a subject designed to discover facts about it.[source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>study</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C63536
code: NPO_1517
preferred name: study

pharmacokinetics study
type: Class
subclass of: pharmacological study
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Pharmacological study of the process by which a drug (or drug-containing material) is absorbed, distributed, metabolized, and eliminated by the body.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>pharmacokinetics study</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: A study of what the body does to a drug or a drug-containing material (e.g., drug-loaded nanoparticle).
DB xref ID: NCIT:C49663
code: NPO_1518
synonym: PK Study
synonym: pharmacokinetic study
synonym: pharmacokinetics
preferred name: pharmacokinetics study

pharmacological study
type: Class
subclass of: study
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Study of the characteristics, effects, and uses of drugs and their interactions with living organisms.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>pharmacological study</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1519
preferred name: pharmacological study
synonym: pharmacology

d-block element
type: Class
subclass of: block element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electrons occupy d-orbitals.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>d-block element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_152
preferred name: d-block element

toxicology study
type: Class
subclass of: pharmacological study
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Pharmacological study of the toxicity effects of a drug or drug-containing material.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>toxicology study</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1520
preferred name: toxicology study

pharmacokinetic property
type: Class
subclass of: realizable_entity
subclass of: Restriction
  on property: property determined from
  some values from: pharmacokinetics study
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A property that is characteristic of the absorption, distribution, metabolism and elimination of a drug by the body.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>pharmacokinetic property</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1521
preferred name: pharmacokinetic property

elimination half life
type: Class
subclass of: half life
subclass of: Restriction
  on property: property determined from
  some values from: pharmacokinetics study
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The time required for half of an exogenous substance to be removed from either the plasma or whole or part of the body.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>elimination half life</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C70915
code: NPO_1522
synonym: biological half life
preferred name: elimination half life

area under the plasma concentration time curve
type: Class
subclass of: pharmacokinetic parameter
subclass of: Restriction
  on property: parameter determined from
  some values from: pharmacokinetics study
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The area under the curve in a plot of concentration of a drug in plasma against time</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>area under the plasma concentration time curve</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: AUC
code: NPO_1523
synonym: area under curve
preferred name: area under the plasma concentration time curve

volume of distribution
type: Class
subclass of: pharmacokinetic parameter
subclass of: Restriction
  on property: parameter determined from
  some values from: pharmacokinetics study
subclass of: Restriction
  on property: has unit of measure
  some values from: volume unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The amount of drug in the body divided by its concentration in the blood.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>volume of distribution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1524
synonym: Vd
preferred name: volume of distribution

drug clearance
type: Class
subclass of: pharmacokinetic parameter
subclass of: Restriction
  on property: parameter determined from
  some values from: pharmacokinetics study
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The volume of plasma from which the drug is completely removed per unit time</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>drug clearance</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: CI
code: NPO_1525
synonym: clearance
preferred name: drug clearance

elimination rate constant
type: Class
subclass of: pharmacokinetic parameter
subclass of: Restriction
  on property: parameter determined from
  some values from: pharmacokinetics study
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A first-order rate constant that determines the rate at which drugs are eliminated from the body.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>elimination rate constant</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1526
preferred name: elimination rate constant
synonym: kel

Cmax
type: Class
subclass of: pharmacokinetic parameter
subclass of: Restriction
  on property: parameter determined from
  some values from: pharmacokinetics study
subclass of: Restriction
  on property: has unit of measure
  some values from: concentration unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The maximum concentration of an experimental substance or drug in the plasma or a target organ after dose administration. [source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Cmax</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Cmax
DB xref ID: NCIT:C70918
code: NPO_1527
synonym: maximum concentration
synonym: peak concentration

Tmax
type: Class
subclass of: pharmacokinetic parameter
subclass of: Restriction
  on property: parameter determined from
  some values from: pharmacokinetics study
subclass of: Restriction
  on property: has unit of measure
  some values from: time unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The length of time it takes to reach the maximum concentration (Cmax) of an exogenous compound or drug in the plasma or a tissue after a dose is administered.[source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Tmax</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C70919
code: NPO_1528
preferred name: Tmax
synonym: time to maximum concentration
synonym: time to peak concentration

bioavailability
type: Class
subclass of: pharmacokinetic property
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Fraction of the administered dose which reaches the systemic circulation and is available at the site of action.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>bioavailability</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1529
preferred name: bioavailability

nanoparticle response to magnetic field
type: Class
subclass of: nanoparticle response to external stimulus
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to external stimulus, which occurs in response to ultrasound.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanoparticle response to magnetic field</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_153
preferred name: nanoparticle response to magnetic field

pharmacokinetic parameter
type: Class
subclass of: parameter
subclass of: Restriction
  on property: parameter determined from
  some values from: pharmacokinetics study
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A parameter measured or calculated in a pharmacokinetic study.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>pharmacokinetic parameter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1530
preferred name: pharmacokinetic parameter

tumor imaging
type: Class
subclass of: imaging
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Imaging the size, shape, surface and structural properties of tumors.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tumor imaging</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1531
synonym: imaging of tumors
preferred name: tumor imaging

detection of tumors
type: Class
subclass of: detection
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Detection of the presence or growth of tumors in the body of a human or an animal model.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>detection of tumors</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1532
preferred name: detection of tumors
synonym: tumor detection

therapeutic payload agent
type: Class
subclass of: chemical component in nanoparticle formulation
subclass of: Restriction
  on property: has function
  some values from: therapeutic function
subclass of: Restriction
  on property: has role
  some values from: payload agent role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component in a nanoparticle formulation that is a bearer of imaging function and has payload agent role.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>therapeutic payload agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1533
preferred name: therapeutic payload agent

imaging payload agent
type: Class
subclass of: chemical component in nanoparticle formulation
subclass of: Restriction
  on property: has function
  some values from: imaging function
subclass of: Restriction
  on property: has role
  some values from: payload agent role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component in a nanoparticle formulation that is a bearer of imaging function and payload agent role.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>imaging payload agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1534
preferred name: imaging payload agent

tumor angiogenesis
type: Class
subclass of: angiogenesis
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Angiogenesis which is the formation of new blood vessels that supply oxygen and nutrients to a tumor for its growth and maintenance.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tumor angiogenesis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C19361
code: NPO_1535
preferred name: tumor angiogenesis

inorganic nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: inorganic molecular entity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of inorganic molecular entities.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>inorganic nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1536
preferred name: inorganic nanoparticle

superparamagnetic nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Class
    union of: Restriction
      on property: has component part
      some values from: Class
        intersection of: material entity
        intersection of: Restriction
    union of: Restriction
      on property: has property
      some values from: superparamagnetic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has superparamagnetic properties.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>superparamagnetic nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1537
preferred name: superparamagnetic nanoparticle

pH-sensitive polymeric nanoparticle
type: Class
equivalent class: Class
  intersection of: polymeric nanoparticle
  intersection of: Class
    union of: Restriction
      on property: has component part
      some values from: Class
        intersection of: molecular entity
        intersection of: Restriction
    union of: Restriction
      on property: has property
      some values from: pH-sensitive
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polymeric nanoparticle which consists of molecular components that are pH-sensitive.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>pH-sensitive polymeric nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1538
preferred name: pH-sensitive polymeric nanoparticle

particle diameter
type: Class
subclass of: particle size
subclass of: Restriction
  on property: has unit of measure
  some values from: length unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Diameter which inheres in a particle.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>particle diameter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1539
preferred name: particle diameter

rhodium
type: Class
subclass of: element
disjoint with: germanium
disjoint with: mendelevium
disjoint with: iodine
disjoint with: nitrogen
disjoint with: meitnerium
disjoint with: lawrencium
disjoint with: einsteinium
disjoint with: beryllium
disjoint with: mercury
disjoint with: boron
disjoint with: dysprosium
disjoint with: radon
disjoint with: magnesium
disjoint with: calcium
disjoint with: protactinium
disjoint with: fluorine
disjoint with: neodymium
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten

metal oxide
type: Class
equivalent class: Class
  intersection of: oxide
  intersection of: Restriction
    on property: has part
    some values from: metal
  intersection of: Restriction
    on property: has quality
    some values from: inorganic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of metal.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>metal oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1540
preferred name: metal oxide

metal oxide nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: metal oxide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of a metal oxide.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>metal oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1541
preferred name: metal oxide nanoparticle

zinc oxide nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: zinc oxide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of zinc oxide.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>zinc oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1542
synonym: ZnO nanoparticle
preferred name: zinc oxide nanoparticle

zinc oxide
type: Class
subclass of: oxide
subclass of: Restriction
  on property: has quality
  some values from: inorganic
subclass of: Restriction
  on property: has part
  some values from: zinc
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of zinc.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>zinc oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1543
synonym: ZnO
preferred name: zinc oxide

copper oxide nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: copper oxide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of copper oxide.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>copper oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1544
preferred name: copper oxide nanoparticle

copper oxide
type: Class
subclass of: oxide
subclass of: Restriction
  on property: has part
  some values from: copper
subclass of: Restriction
  on property: has quality
  some values from: inorganic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of copper.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>copper oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1545
preferred name: copper oxide

copper (I) oxide
type: Class
subclass of: copper oxide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of copper having the chemical formula Cu2O.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>copper (I) oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: Cu2O
code: NPO_1546
preferred name: copper (I) oxide
synonym: cuprous oxide

copper (II) oxide
type: Class
subclass of: copper oxide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of copper having the chemical formula CuO.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>copper (II) oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: CuO
code: NPO_1547
preferred name: copper (II) oxide
synonym: cupric oxide

iron (II,III) oxide nanoparticle
type: Class
equivalent class: Class
  intersection of: iron oxide nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: iron (II,III) oxide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iron oxide nanoparticle which is basically composed of iron(II,III) oxide.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>iron (II,III) oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: Fe3O4 nanoparticle
code: NPO_1548
preferred name: iron (II,III) oxide nanoparticle

dextran-coated iron oxide nanoparticle
type: Class
equivalent class: Class
  intersection of: iron oxide nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: Class
      intersection of: dextran
      intersection of: Restriction
        on property: has role
        some values from: nanoparticle surface modifying role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iron oxide nanoparticle coated with dextran.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dextran-coated iron oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1549
preferred name: dextran-coated iron oxide nanoparticle
synonym: iron oxide nanoparticle coated with dextran

iron (III) oxide nanoparticle
type: Class
equivalent class: Class
  intersection of: iron oxide nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: iron (III) oxide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of iron (III) oxide.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>iron (III) oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: Fe2O3 nanoparticle
code: NPO_1550
preferred name: iron (III) oxide nanoparticle

spherical nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has quality
    some values from: spherical shape
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has spherical shape.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>spherical nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1551
preferred name: spherical nanoparticle

lipid nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: lipid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of lipid molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>lipid nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1552
preferred name: lipid nanoparticle

fluorescent silica nanoparticle
type: Class
equivalent class: Class
  intersection of: silica nanoparticle
  intersection of: Class
    union of: Restriction
      on property: has component part
      some values from: Class
        intersection of: molecular entity
        intersection of: Restriction
    union of: Restriction
      on property: has property
      some values from: fluorescent
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A silica nanoparticle which has fluorescent property.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fluorescent silica nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1553
preferred name: fluorescent silica nanoparticle

gelatin
type: Class
subclass of: protein
subclass of: Restriction
  on property: has property
  some values from: soluble in water
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A colorless water-soluble glutinous protein obtained from animal tissues such as bone and skin. (source: Word Net)</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gelatin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1554
preferred name: gelatin

gelatin nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: gelatin
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of gelatin.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gelatin nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1555
preferred name: gelatin nanoparticle

Poly(lactic-co-glycolic acid)
type: Class
subclass of: polymer
subclass of: Restriction
  on property: has property
  some values from: biodegradable
subclass of: Restriction
  on property: has property
  some values from: biocompatible
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A synthetic copolymer of lactic acid and glycolic acid.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Poly(lactic-co-glycolic acid)</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1556
synonym: PLGA
synonym: PLGA polymer
preferred name: Poly(lactic-co-glycolic acid)
comment: drug targeted against protein of tumor cell

PLGA nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: Poly(lactic-co-glycolic acid)
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of poly(lactic-co-glycolic acid) polymer.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>PLGA nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1559
preferred name: PLGA nanoparticle
synonym: poly(lactic-co-glycolic acid) nanoparticle

ellipsoidal shape
type: Class
subclass of: shape
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shape formed by the surface of a 3-dimensional object, having elliptical or circular plane sections.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ellipsoidal shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_156
synonym: ellipsoidal
preferred name: ellipsoidal shape

fluorescent core-shell silica nanoparticle
type: Class
equivalent class: Class
  intersection of: fluorescent silica nanoparticle
  intersection of: Restriction
    on property: has part
    some values from: core
  intersection of: Restriction
    on property: has part
    some values from: shell
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fluorescent silica nanoparticle which has a core-shell structure.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fluorescent core-shell silica nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1562
preferred name: fluorescent core-shell silica nanoparticle

hydroxyapatite nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: hydroxyapatite
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of hydroxyapatite.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydroxyapatite nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1568
preferred name: hydroxyapatite nanoparticle

gadolinium-loaded nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has part
    some values from: Class
      intersection of: gadolinium ion
      intersection of: Restriction
        on property: has role
        some values from: payload agent role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is loaded with gadolinium ions.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gadolinium-loaded nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1569
preferred name: gadolinium-loaded nanoparticle

single-walled nanotube
type: Class
subclass of: nanotube
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanotube which consists of a single layer or sheet of hexagonal arrays of an element or molecule, rolled into a seamless cylinder with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>single-walled nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_157
preferred name: single-walled nanotube

gadolinium ion
type: Class
equivalent class: Class
  intersection of: ion
  intersection of: Restriction
    on property: has part
    some values from: gadolinium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ion of gadolinium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gadolinium ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1570
preferred name: gadolinium ion

chitosan-coated magnetic nanoparticle
type: Class
equivalent class: Class
  intersection of: magnetic nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: Class
      intersection of: chitosan
      intersection of: Restriction
        on property: has role
        some values from: nanoparticle surface modifying role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A magnetic nanoparticle which consists of a coating agent composed of chitosan.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>chitosan-coated magnetic nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1571
preferred name: chitosan-coated magnetic nanoparticle

core-shell silica nanoparticle
type: Class
equivalent class: Class
  intersection of: silica nanoparticle
  intersection of: Restriction
    on property: has part
    some values from: core
  intersection of: Restriction
    on property: has part
    some values from: shell
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A silica nanoparticle which has a core-shell structure.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>core-shell silica nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1572
preferred name: core-shell silica nanoparticle

tumor
type: Class
subclass of: biological material entity
subclass of: Restriction
  on property: has part
  some values from: tumor cell
subclass of: Restriction
  on property: has quality
  some values from: tumor size
subclass of: Restriction
  on property: has part
  some values from: tumor extracellular space
subclass of: Restriction
  on property: has quality
  some values from: tumor pH
subclass of: Restriction
  on property: has quality
  some values from: tumor weight
subclass of: Restriction
  on property: has quality
  some values from: tumor volume
definition: <ncicp:ComplexDefinition><ncicp:def-definition>An abnormal mass of tissue that results from uncontrolled proliferation of cells. It performs no bodily function. It may be benign (non-cancerous) or malignant (cancerous).</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tumor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C3262
code: NPO_1573
synonym: neoplasm
preferred name: tumor

solid tumor
type: Class
subclass of: tumor
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A benign or malignant tumor arising from tissues that do not include fluid areas.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>solid tumor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C9292
code: NPO_1574
synonym: solid neoplasm
preferred name: solid tumor

tumor pH
type: Class
equivalent class: Class
  intersection of: pH
  intersection of: Restriction
    on property: quality of
    some values from: tumor
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The pH inhering in a tumor.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tumor pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1575
preferred name: tumor pH

intracellular pH
type: Class
equivalent class: Class
  intersection of: pH
  intersection of: Restriction
    on property: quality of
    some values from: intracellular fluid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>pH of the intracellular fluid in a cell.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>intracellular pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1576
preferred name: intracellular pH
synonym: pHi

intracellular fluid
type: Class
subclass of: biological fluid
subclass of: Restriction
  on property: contained in
  some values from: intracellular space
subclass of: Restriction
  on property: has quality
  some values from: intracellular pH
definition: <ncicp:ComplexDefinition><ncicp:def-definition>The fluid inside cells.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>intracellular fluid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: MeSH: D007424
code: NPO_1577
preferred name: intracellular fluid

extracellular fluid
type: Class
subclass of: biological fluid
subclass of: Restriction
  on property: has quality
  some values from: extracellular pH
subclass of: Restriction
  on property: contained in
  some values from: extracellular space
definition: <ncicp:ComplexDefinition><ncicp:def-definition>The body fluid outside of cells.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>extracellular fluid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: MeSH: D045604
code: NPO_1578
preferred name: extracellular fluid
synonym: intercellular fluid

extracellular pH
type: Class
equivalent class: Class
  intersection of: pH
  intersection of: Restriction
    on property: quality of
    some values from: extracellular fluid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>pH of the extracellular fluid.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>extracellular pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1579
preferred name: extracellular pH
synonym: pHe

intracellular space
type: Class
subclass of: material site
subclass of: Restriction
  on property: contains
  some values from: intracellular fluid
subclass of: Restriction
  on property: part of
  some values from: cell
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The space within a cell, which contains the intracellular fluid.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>intracellular space</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: MeSH:D042541
code: NPO_1581
preferred name: intracellular space

tumor extracellular pH
type: Class
equivalent class: Class
  intersection of: tumor pH
  intersection of: Restriction
    on property: quality of
    some values from: tumor extracellular fluid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>pH of the extracellular fluid in a tumor.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tumor extracellular pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1582
preferred name: tumor extracellular pH

tumor extracellular space
type: Class
equivalent class: Class
  intersection of: extracellular space
  intersection of: Restriction
    on property: part of
    some values from: tumor
subclass of: Restriction
  on property: contains
  some values from: tumor extracellular fluid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Extracellular space in a tumor, which contains the tumor extracellular fluid.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tumor extracellular space</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1583
synonym: extracellular space in tumor
synonym: extracellular space of tumor
preferred name: tumor extracellular space

tumor cell
type: Class
subclass of: cell
subclass of: Restriction
  on property: has part
  some values from: intracellular space of tumor cell
subclass of: Restriction
  on property: part of
  some values from: tumor
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Cell of, or derived from, a tumor.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tumor cell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1584
preferred name: tumor cell

intracellular fluid in a tumor cell
type: Class
equivalent class: Class
  intersection of: intracellular fluid
  intersection of: Restriction
    on property: contained in
    some values from: intracellular space of tumor cell
  intersection of: Restriction
    on property: has quality
    some values from: tumor intracellular pH
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Intracellular fluid inside tumor cells.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>intracellular fluid in a tumor cell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1585
preferred name: intracellular fluid in a tumor cell
synonym: intracellular fluid in tumor cells
synonym: intracellular fluid of tumor cells

tumor extracellular fluid
type: Class
equivalent class: Class
  intersection of: extracellular fluid
  intersection of: Restriction
    on property: contained in
    some values from: tumor extracellular space
  intersection of: Restriction
    on property: has quality
    some values from: tumor extracellular pH
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Extracellular fluid inside a tumor.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tumor extracellular fluid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1586
preferred name: tumor extracellular fluid

intracellular space of tumor cell
type: Class
equivalent class: Class
  intersection of: intracellular space
  intersection of: Restriction
    on property: part of
    some values from: tumor cell
subclass of: Restriction
  on property: contains
  some values from: intracellular fluid in a tumor cell
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Intracellular space within a tumor cell.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>intracellular space of tumor cell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1587
preferred name: intracellular space of tumor cell
synonym: intracellular space of tumor cells

tumor intracellular pH
type: Class
equivalent class: Class
  intersection of: tumor pH
  intersection of: Restriction
    on property: quality of
    some values from: intracellular fluid in a tumor cell
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>pH of the intracellular fluid in a tumor cell.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tumor intracellular pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1588
preferred name: tumor intracellular pH

cirulating half life
type: Class
subclass of: elimination half life
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The time taken for the concentration of an exogenous substance in the blood plasma to reduce by 50%</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cirulating half life</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1589
synonym: circulation half life
preferred name: cirulating half life
synonym: plasma half life

thioether linkage between thiol and maleimide derivative
type: Class
subclass of: thioether linkage
subclass of: Restriction
  on property: part of
  some values from: thioether group
subclass of: Restriction
  on property: derives from
  some values from: maleimide group
subclass of: Restriction
  on property: derives from
  some values from: sulfhydryl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thioether linkage which is formed between a thiol and a maleimide derivative, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thioether linkage between thiol and maleimide derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_159
preferred name: thioether linkage between thiol and maleimide derivative

long circulating half life
type: Class
subclass of: cirulating half life
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A circulating half life inhering in an exogenous substance (drug, nanoparticle, imaging agent) and is exhibited when it circulates in the blood plasma for a longer time compared to a reference.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>long circulating half life</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1590
preferred name: long circulating half life
synonym: long circulation half-life

long circulating nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has property
    some values from: long circulating half life
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a circulating half life longer than that of a reference substance.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>long circulating nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1591
preferred name: long circulating nanoparticle

cell surface receptor
type: Class
subclass of: receptor
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A receptor that is localized to the plasma membrane and may have exposure to the extracellular milieu. [source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cell surface receptor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C17067
code: NPO_1592
preferred name: cell surface receptor

folate receptor
type: Class
subclass of: cell surface receptor
subclass of: Restriction
  on property: participates in
  some values from: folate receptor mediated endocytosis
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cell surface receptor that binds to folic acid and reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells..</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>folate receptor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1594
preferred name: folate receptor
synonym: folate-binding protein

growth factor receptor
type: Class
subclass of: cell surface receptor
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cell surface receptor which binds to extracellular polypeptide molecules triggering intracellular signaling pathways that activate various cellular responses such as cell proliferation and/or differentiation. (source:NCI)</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>growth factor receptor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C17664
code: NPO_1595
preferred name: growth factor receptor

fiat material part
type: Class
subclass of: material entity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A material entity [npo:MaterialEntity] that is part of a material entity but is not demarcated by any physical discontinuities.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fiat material part</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1597
preferred name: fiat material part

fluorescence imaging
type: Class
subclass of: optical imaging
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An optical imaging technique in which images are captured based on contrast provided by the fluorescence emitted from a fluorescent molecule when excited by a light of certain wavelength.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fluorescence imaging</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1598
preferred name: fluorescence imaging

optical imaging
type: Class
subclass of: imaging technique
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imaging technique, which encompasses many different techniques that use light of the UV to the NIR spectral region to visualize tissue optical characteristics imparted through absorption and scattering of light, as well as emission of fluorescence. [source: abstract from book chapter " Kai Licha, Contast Agents for Optical Imaging, vol. 222/2002, Contast Agents II, 2002."]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>optical imaging</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1599
preferred name: optical imaging

cadmium selenide quantum dot
type: Class
subclass of: quantum dot
subclass of: Restriction
  on property: has component part
  some values from: cadmium selenide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quantum dot composed of cadmium selenide.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cadmium selenide quantum dot</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: CdSe quantum dot
code: NPO_160
preferred name: cadmium selenide quantum dot

labeling molecule
type: Class
equivalent class: Class
  intersection of: compound for imaging
  intersection of: Restriction
    on property: has role
    some values from: labeling role
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which is used to label a chemical entity for purposes of identification or detection.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>labeling molecule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1602
preferred name: labeling molecule
synonym: molecular label

dye
type: Class
equivalent class: Class
  intersection of: labeling molecule
  intersection of: Restriction
    on property: has role
    some values from: dye role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A labeling molecule or substance that is used to stain and color other material entities.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dye</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1603
preferred name: dye

fluorescent dye
type: Class
equivalent class: Class
  intersection of: dye
  intersection of: Restriction
    on property: has property
    some values from: fluorescent
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fluorescent dye</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: A dye which has the property to shine or glow brightly due to fluorescence.
code: NPO_1604
preferred name: fluorescent dye

dye role
type: Class
subclass of: labeling role
subclass of: Restriction
  on property: role of
  some values from: dye
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A labeling role played by a molecular entity when it is used for dyeing another material entity.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dye role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1605
preferred name: dye role

target
type: Class
equivalent class: Class
  intersection of: material entity
  intersection of: Restriction
    on property: has role
    some values from: Class
      intersection of: target role
      intersection of: Restriction
        on property: is realized in
        some values from: targeting
subclass of: Restriction
  on property: participates in
  some values from: targeting
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A material entity which is targeted by another material entity during the process of targeting.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>target</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1606
preferred name: target

targeting
type: Class
subclass of: process
subclass of: Restriction
  on property: realizes
  some values from: target role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The process of directing a material entity to another material entity at a specific location.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>targeting</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1607
preferred name: targeting

emulsifying role
type: Class
subclass of: agent role
subclass of: Restriction
  on property: role of
  some values from: emulsifier
subclass of: Restriction
  on property: is realized in
  some values from: emulsification
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An agent role which inheres in a molecule or compound that causes the stabilization of or formation of an emulsion during the process of emulsification.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>emulsifying role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1608
preferred name: emulsifying role

emulsification
type: Class
subclass of: process
subclass of: Restriction
  on property: has output participant
  some values from: emulsion
subclass of: Restriction
  on property: has agent
  some values from: emulsifier
subclass of: Restriction
  on property: realizes
  some values from: emulsifying role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process in which two immiscible liquids are mixed to form an emulsion.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>emulsification</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1609
preferred name: emulsification

drug directed against intracellular domain of membrane receptor
type: Class
subclass of: drug directed against membrane receptor
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that crosses the tumor cell membrane and blocks the intracellular domain of a membrane receptor.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>drug directed against intracellular domain of membrane receptor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_161
preferred name: drug directed against intracellular domain of membrane receptor

phase
type: Class
subclass of: chemical substance by physical state
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A substance or a portion of a substance, which has uniform physical and chemical properties.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>phase</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1610
preferred name: phase

solid phase
type: Class
equivalent class: Class
  intersection of: phase
  intersection of: Restriction
    on property: has quality
    some values from: solid state
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phase which is in the solid state.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>solid phase</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1611
preferred name: solid phase

liquid phase
type: Class
equivalent class: Class
  intersection of: phase
  intersection of: Restriction
    on property: has quality
    some values from: liquid state
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phase which is in the liquid state.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>liquid phase</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1612
preferred name: liquid phase

gas phase
type: Class
equivalent class: Class
  intersection of: phase
  intersection of: Restriction
    on property: has quality
    some values from: gaseous state
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phase which is in the gaseous state.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gas phase</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1613
preferred name: gas phase

dispersed phase
type: Class
subclass of: phase
subclass of: Restriction
  on property: part of
  some values from: colloid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phase which is dispersed in a colloidal system.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dispersed phase</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1614
preferred name: dispersed phase

continuous phase
type: Class
subclass of: phase
subclass of: Restriction
  on property: part of
  some values from: colloid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phase which is medium of dispersion for the dispersed phase in a colloid.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>continuous phase</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1615
preferred name: continuous phase

functionalization of nanoparticle
type: Class
subclass of: process
subclass of: Restriction
  on property: has participant
  some values from: Class
    intersection of: molecular entity
    intersection of: Restriction
      on property: has role
      some values from: functionalizing role
subclass of: Restriction
  on property: has participant
  some values from: nanoparticle component
subclass of: Restriction
  on property: has agent
  some values from: functionalizing agent
subclass of: Restriction
  on property: realizes
  some values from: functionalizing role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process in which a nanoparticle is functionalized by linking it to a molecular entity that adds or modifies the properties or functions of the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>functionalization of nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1616
preferred name: functionalization of nanoparticle

core
type: Class
subclass of: fiat material part
subclass of: Restriction
  on property: has quality
  some values from: core composition
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A fiat material part which forms the basic structure or central part of an object.</ncicp:def-definition><ncicp:Definition_Review_Date>100610</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1617
preferred name: core

antibiotic role
type: Class
subclass of: inhibitor role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An inhibitor role borne by a molecule produced by, and obtained from, certain living cells (especially bacteria, yeasts and moulds), or an equivalent synthetic molecule, which is biostatic or biocidal at low concentrations to some other form of life, especially pathogenic or noxious organisms.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>antibiotic role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1618
preferred name: antibiotic role
comment: definition based on CHEBI:22582 [antibiotic]

antimetabolite role
type: Class
subclass of: inhibitor role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecule role inhering in molecule, which is structurally similar to a metabolite, which competes with it or replaces it, and so prevents or reduces its normal utilization.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>antimetabolite role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1619
preferred name: antimetabolite role
comment: definition based on CHEBI:35221 [antimetabolite]

Group 1 Element
type: Class
equivalent class: Class
  union of: francium
  union of: caesium
  union of: rubidium
  union of: hydrogen
  union of: potassium
  union of: lithium
  union of: sodium
subclass of: group element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 1 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Group 1 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Group 1 Element
code: NPO_162

binding function
type: Class
subclass of: function
subclass of: Restriction
  on property: is realized in
  some values from: binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A function inherining in a molecule that has an essential end-directed activity to bind to other molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>binding function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1622
preferred name: binding function

DNA crosslinking
type: Class
subclass of: DNA modification
subclass of: Restriction
  on property: has agent
  some values from: DNA crosslinking agent
subclass of: Restriction
  on property: negatively regulates
  some values from: DNA replication
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process which involves the formation of a covalent bond between two bases on DNA. (NCI)</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>DNA crosslinking</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: DNA crosslinking
DB xref ID: NCIT:C25827
code: NPO_1623
synonym: crosslinking of DNA

alkylating function
type: Class
subclass of: function
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A function inhering in a molecule that has the end-directed activity to introduce its one or more alkyl groups to another molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>alkylating function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1626
preferred name: alkylating function

DNA intercalator role
type: Class
subclass of: molecular role
subclass of: Restriction
  on property: is realized in
  some values from: DNA intercalation
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular role inhering in a molecule and is realized during the reversible inclusion of the molecule (or group) between the base pairs of a DNA strand.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>DNA intercalator role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: DNA intercalator role
code: NPO_1627

DNA intercalation
type: Class
subclass of: DNA binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>DNA binding which involves insertion by covalent linkage of a molecule into the double-stranded deoxyribonucleotide polymer between the internal purine and pyrimidine base pairs stacked one on another perpendicular to the double helix axis.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>DNA intercalation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: DNA intercalation
DB xref ID: NCIT:C40492
code: NPO_1628

simple protein
type: Class
subclass of: protein
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A protein that yields only amino acids when hydrolyzed. It does not contain a prosthetic group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>simple protein</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_163
comment: [definition source]: http://www.thefreedictionary.com, L. G. Wade Jr. Organic Chemistry 3rd Edition
preferred name: simple protein

antagonist role
type: Class
subclass of: inhibitor role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An inhibitor role inhering in a molecule that inhibits the metabolism or activity of a molecule that initiates a physiological response when combined with a receptor.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>antagonist role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1630
preferred name: antagonist role

inhibition of folic acid metabolism
type: Class
equivalent class: Restriction
  on property: negatively regulates
  some values from: folic acid metabolic process
subclass of: negative regulation of biological process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An inhibition which involves interference with, or restraint of, the activities of enzymatic biotransforming chemical modifications of folic acid.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>inhibition of folic acid metabolism</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C40643
code: NPO_1633
synonym: folic acid metabolism inhibition
synonym: inhibition of folate metabolism
preferred name: inhibition of folic acid metabolism

inhibition of dihydrofolate reductase activity
type: Class
equivalent class: Restriction
  on property: negatively regulates
  some values from: dihydrofolate reductase activity
subclass of: enzyme inhibition
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of dihydrofolate reductase.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>inhibition of dihydrofolate reductase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1634
preferred name: inhibition of dihydrofolate reductase activity

germanium
type: Class
subclass of: element
disjoint with: mendelevium
disjoint with: iodine
disjoint with: nitrogen
disjoint with: meitnerium
disjoint with: lawrencium
disjoint with: einsteinium
disjoint with: beryllium
disjoint with: mercury
disjoint with: boron
disjoint with: dysprosium
disjoint with: radon
disjoint with: magnesium
disjoint with: calcium
disjoint with: protactinium
disjoint with: fluorine
disjoint with: neodymium
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel

regulator role
type: Class
subclass of: agent role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular role inhering in a molecule that causes the regulation of a process or the activity of another molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>regulator role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1641
preferred name: regulator role

surface modification of nanoparticle
type: Class
subclass of: macroscopic synthesis part
subclass of: Restriction
  on property: has agent
  some values from: surface modifying agent
subclass of: Restriction
  on property: has output participant
  some values from: surface modified nanoparticle
subclass of: Restriction
  on property: realizes
  some values from: nanoparticle surface modifying role
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A process which is performed to modify the surface of a nanoparticle using surface modifying agents.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>surface modification of nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1642
preferred name: surface modification of nanoparticle

inhibition of metastasis
type: Class
subclass of: antitumor activity
subclass of: Restriction
  on property: negatively regulates
  some values from: metastasis
subclass of: Restriction
  on property: realizes
  some values from: inhibitor role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antitumor activity which inhibits or blocks metastasis.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>inhibition of metastasis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1649
preferred name: inhibition of metastasis

inhibition of DNA topoisomerase type I activity
type: Class
equivalent class: Restriction
  on property: negatively regulates
  some values from: DNA topoisomerase type I activity
subclass of: enzyme inhibition
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of topoisomerase type I</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>inhibition of DNA topoisomerase type I activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1656
preferred name: inhibition of DNA topoisomerase type I activity

inhibition of DNA topoisomerase type II activity
type: Class
equivalent class: Restriction
  on property: negatively regulates
  some values from: DNA topoisomerase type II activity
subclass of: enzyme inhibition
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of topoisomerase type II</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>inhibition of DNA topoisomerase type II activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1657
preferred name: inhibition of DNA topoisomerase type II activity

inhibition of DNA topoisomerase activity
type: Class
equivalent class: Restriction
  on property: negatively regulates
  some values from: DNA topoisomerase activity
subclass of: enzyme inhibition
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of DNA topoisomerase.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>inhibition of DNA topoisomerase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1658
preferred name: inhibition of DNA topoisomerase activity

inhibition of thymidylate synthase activity
type: Class
equivalent class: Restriction
  on property: negatively regulates
  some values from: thymidylate synthase activity
subclass of: enzyme inhibition
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of thymidylate synthase.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>inhibition of thymidylate synthase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1659
preferred name: inhibition of thymidylate synthase activity

fluorescence imaging contrast agent
type: Class
equivalent class: Class
  intersection of: optical imaging contrast agent
  intersection of: Restriction
    on property: has application
    some values from: fluorescence imaging
  intersection of: Restriction
    on property: has property
    some values from: fluorescent
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An optical imaging contrast agent, which is fluorescent, and provides contrast in images captured using fluorescence imaging techniques.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fluorescence imaging contrast agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_166
synonym: contrast agent in fluorescence imaging
preferred name: fluorescence imaging contrast agent

inhibition of protein kinase activity
type: Class
equivalent class: Restriction
  on property: negatively regulates
  some values from: protein kinase activity
subclass of: enzyme inhibition
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of protein kinase</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>inhibition of protein kinase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1660
preferred name: inhibition of protein kinase activity

inhibition of protein tyrosine kinase activity
type: Class
equivalent class: Restriction
  on property: negatively regulates
  some values from: protein tyrosine kinase activity
subclass of: enzyme inhibition
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of protein tyrosine kinase.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>inhibition of protein tyrosine kinase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1661
preferred name: inhibition of protein tyrosine kinase activity

agent role
type: Class
subclass of: molecular role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular role inhering in a molecule that causes the occurrence of a process.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>agent role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1663
preferred name: agent role

mendelevium
type: Class
subclass of: element
disjoint with: iodine
disjoint with: nitrogen
disjoint with: meitnerium
disjoint with: lawrencium
disjoint with: einsteinium
disjoint with: beryllium
disjoint with: mercury
disjoint with: boron
disjoint with: dysprosium
disjoint with: radon
disjoint with: magnesium
disjoint with: calcium
disjoint with: protactinium
disjoint with: fluorine
disjoint with: neodymium
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium

parameter
type: Class
subclass of: generically_dependent_continuant
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A generically dependent continuant [snap:GenericallyDependentContinuant] which is 1) a constant in the equation of a curve that can be varied to yield a family of similar curves; or 2) any factor that defines a system and determines (or limits) its performance; or 3) a quantity (such as mean or variance) that characterizes a statistical population and that can be estimated by calculations from sample data.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>WordNet</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>parameter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1680
preferred name: parameter

wave parameter
type: Class
subclass of: parameter
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A parameter which characterizes a wave pattern.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>wave parameter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1681
preferred name: wave parameter

wave amplitude
type: Class
subclass of: wave parameter
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>Amplitude of a wave pattern.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>wave amplitude</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1682
preferred name: wave amplitude

wave frequency
type: Class
subclass of: wave parameter
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>Frequency of a wave pattern</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>wave frequency</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1683
preferred name: wave frequency

wave speed
type: Class
subclass of: wave parameter
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>Speed of a wave pattern</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>wave speed</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1684
preferred name: wave speed

collective quality
type: Class
subclass of: quality
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a group (whole) of multiple bearers of the same or different kinds. Two or more bearers should exist together for this quality to exist. This quality derives from an individual quality common to all the bearers in the group.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>collective quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1685
preferred name: collective quality

individual quality
type: Class
subclass of: quality
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a single bearer as a whole.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>individual quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1686
preferred name: individual quality

general individual quality
type: Class
subclass of: individual quality
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An individual quality which inheres in a single bearer AND NOT specific to the type of bearer AND inheres in other single bearers existing by themselves independently of each other. Therefore, this quality can inhere in more than one type of single bearers.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>general individual quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1687
preferred name: general individual quality

specific individual quality
type: Class
subclass of: individual quality
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An individual quality which inheres in a single bearer AND specific to the type of bearer.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>specific individual quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1688
preferred name: specific individual quality

dependent general individual quality
type: Class
subclass of: general individual quality
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A general individual quality which inheres in a single bearer AND NOT specific to the type of single bearer AND the bearer needs other entities (bearers or non-bearers) to exist along with it or within it to have this quality; therefore, dependent. This quality inheres in the bearer in relation to other entities.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>dependent general individual quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1689
preferred name: dependent general individual quality

iodine
type: Class
subclass of: element
disjoint with: nitrogen
disjoint with: meitnerium
disjoint with: lawrencium
disjoint with: einsteinium
disjoint with: beryllium
disjoint with: mercury
disjoint with: boron
disjoint with: dysprosium
disjoint with: radon
disjoint with: magnesium
disjoint with: calcium
disjoint with: protactinium
disjoint with: fluorine
disjoint with: neodymium
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium

independent general individual quality
type: Class
subclass of: general individual quality
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A general individual quality which inheres in a single bearer AND NOT specific to the type of single bearer AND the bearer do not need other entities (bearers or non-bearers) to exist along with it to have this quality; therefore independent.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>independent general individual quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1690
preferred name: independent general individual quality

dependent specific individual quality
type: Class
subclass of: specific individual quality
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A specific individual quality which inheres in a single bearer AND specific to the type of the single bearer.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>dependent specific individual quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1691
preferred name: dependent specific individual quality

independent specific individual quality
type: Class
subclass of: specific individual quality
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A specific individual quality which inheres in a single bearer AND specific to the type of the single bearer AND the bearer do not need other entities (bearers or non-bearers) to exist along with it to have this quality; therefore, independent.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>independent specific individual quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1692
preferred name: independent specific individual quality

tumor size
type: Class
subclass of: independent specific individual quality
subclass of: Restriction
  on property: quality of
  some values from: tumor
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Size of a tumor.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>tumor size</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1693
synonym: size of tumor
preferred name: tumor size

particle size
type: Class
subclass of: independent specific individual quality
subclass of: Restriction
  on property: quality of
  some values from: particle
subclass of: Restriction
  on property: has unit of measure
  some values from: Class
    union of: length unit
    union of: area unit
    union of: volume unit
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Size of a particle.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>particle size</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1694
preferred name: particle size
synonym: size of particle

independent specific collective quality
type: Class
subclass of: specific collective quality
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A specific collective quality which inheres in a group of multiple bearers AND specific only to the type of bearers in the group, AND the group does not need other entities (non-bearers) to exist along with it as a whole to bear this quality.</ncicp:def-definition><ncicp:Definition_Review_Date>101029</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>independent specific collective quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1695
preferred name: independent specific collective quality

dependent specific collective quality
type: Class
subclass of: specific collective quality
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A specific collective quality which inheres in a group of multiple bearers, AND specific only to the type of bearers in the group, AND the group needs other bearers to exist along with it as a whole to bear this quality.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>dependent specific collective quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1696
preferred name: dependent specific collective quality

size distribution
type: Class
subclass of: polydispersity
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A polydispersity inhering in a collection of objects based on size.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>size distribution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1697
preferred name: size distribution

molecular weight distribution
type: Class
subclass of: polydispersity
subclass of: Restriction
  on property: quality of
  some values from: polymer
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A polydispersity inhering in polymers based on molecular weight.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>molecular weight distribution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1698
preferred name: molecular weight distribution

particle size distribution
type: Class
subclass of: size distribution
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A size distribution inhering in particles.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>particle size distribution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1699
preferred name: particle size distribution

coagulation assay
type: Class
subclass of: biochemical assay
subclass of: Restriction
  on property: uses instrument
  some values from: coagulometer
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An in vitro assay performed to analyze the effect of a nanoparticle formulation or other substance on plasma coagulation.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>NCL assay protocol - ITA-12 (v 1.0)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>coagulation assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1700
synonym: blood clotting assay
synonym: blood coagulation assay
preferred name: coagulation assay

prothrombin time assay
type: Class
subclass of: coagulation assay
subclass of: Restriction
  on property: has endpoint of measurement
  some values from: prothrombin time
subclass of: Restriction
  on property: analyzes
  some values from: extrinsic pathway of blood coagulation
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A coagulation assay which is performed to measure the time it takes for the blood plasma to coagulate in a sample when the coagulation is activated by prothrombin.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>prothrombin time assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1701
synonym: PT assay
preferred name: prothrombin time assay

thrombin time assay
type: Class
subclass of: coagulation assay
subclass of: Restriction
  on property: has endpoint of measurement
  some values from: thrombin time
subclass of: Restriction
  on property: analyzes
  some values from: final common pathway of blood coagulation
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A coagulation assay which is performed to measure the time it takes for the blood plasma to coagulate when the coagulation is activated by thrombin.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>thrombin time assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1702
synonym: TCT assay
synonym: TT assay
synonym: thrombin assay
synonym: thrombin clotting time assay
preferred name: thrombin time assay

activated partial thromboplastin time assay
type: Class
subclass of: coagulation assay
subclass of: Restriction
  on property: analyzes
  some values from: intrinsic pathway of blood coagulation
subclass of: Restriction
  on property: has endpoint of measurement
  some values from: activated partial thromboplastin time
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A coagulation assay which is performed to measure the time it takes for the plasma to coagulate when the coagulation is activated by partial thromboplastin.</ncicp:def-definition><ncicp:Definition_Review_Date>130524</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>activated partial thromboplastin time assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: APTT assay
code: NPO_1703
preferred name: activated partial thromboplastin time assay

reptilase time assay
type: Class
subclass of: coagulation assay
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A coagulation assay which is performed to measure the time taken for the plasma to coagulate in a sample when the coagulation is activated by reptilase.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>reptilase time assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1704
synonym: RT assay
preferred name: reptilase time assay

biochemical assay
type: Class
subclass of: in vitro assay
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An in vitro assay which is performed using purified or crude biochemical reagents in the absence of cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>NCGC assay guidelines (http://ncgc.nih.gov/guidance/glossary.html)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>biochemical assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1705
preferred name: biochemical assay

cell-based assay
type: Class
subclass of: in vitro assay
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An in vitro assay in which the analyzed sample contains live cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>NCGC assay guidelines (http://www.ncgc.nih.gov/guidance/glossary.html)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cell-based assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1706
preferred name: cell-based assay

cytoxicity assay
type: Class
subclass of: cell-based assay
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cell-based assay which is performed to test the cytotoxic effects of a nanoparticle formulation or other substance.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cytoxicity assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1707
preferred name: cytoxicity assay

cell viability assay
type: Class
subclass of: cytoxicity assay
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cytotoxicity assay which is performed to study the cytoxic effects of nanoparticle formulation or other substance on cell viability.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cell viability assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1708
preferred name: cell viability assay

LDH release assay
type: Class
subclass of: cell viability assay
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cell viability assay which is performed by assessing the activity of lactate dehydrogenase (a cytoplasmic enzyme) released into the cell culture supernatant, when the plasma membrane is damaged. LDH release is used as a marker of dead cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>LDH release assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: LDH assay
preferred name: LDH release assay
code: NPO_1709
synonym: lactate dehydrogenase assay

manganese atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: manganese
disjoint with: sodium atom
disjoint with: lanthanum atom
disjoint with: francium atom
disjoint with: caesium atom
disjoint with: nickel atom
disjoint with: fluorine atom
disjoint with: niobium atom
disjoint with: neon atom
disjoint with: promethium atom
disjoint with: mercury atom
disjoint with: zinc atom
disjoint with: potassium atom
disjoint with: neptunium atom
disjoint with: chlorine atom
disjoint with: dubnium atom
disjoint with: radium atom
disjoint with: uranium atom
disjoint with: zirconium atom
disjoint with: rubidium atom
disjoint with: osmium atom
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom

absorption spectroscopy
type: Class
subclass of: spectroscopy
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which measures the intensity of electromagnetic radiation absorbed by a molecular entity or a substance at different wavelengths or frequencies.</ncicp:def-definition><ncicp:Definition_Review_Date>100610</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>absorption spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
editor note: Absorption spectroscopy is used to determine the presence of or amount of a particular substance in a sample from its absorption spectrum. When the sample interacts with the radiating field, the sample absorbs energy, i.e. photons, and the intensity of absorption (radiation absorbed by the sample) varies as a function of frequency, and this variation is the absorption spectrum. (references: wikipedia, May 27, 2010)
code: NPO_1710
preferred name: absorption spectroscopy

emission spectroscopy
type: Class
subclass of: spectroscopy
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which measures the intensity of electromagnetic radiation emitted by a molecular entity or a substance at different wavelengths or frequencies.</ncicp:def-definition><ncicp:Definition_Review_Date>100610</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>emission spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
editor note: Emission spectroscopy is used to determine the elemental composition of a material from its emission spectrum obtained by measuring the intensity of electromagnetic radiation emitted by the atoms or molecules in the material at different wavelengths. Atoms or molecules in a material undergo transition from an excited state to a lower energy state, and during this transition, and they emit photons. Each element emits (radiates) photons at a characteristic set of discrete wavelengths according to its electronic structure. Hence, by examining these wavelengths in the emission spectrum of the material, the elemental composition of the material can be determined. They are different ways to excite the atoms. (based on source: wikipedia, May 27, 2010)
code: NPO_1711
preferred name: emission spectroscopy

light scattering spectroscopy
type: Class
subclass of: spectroscopy
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which measures the intensity of light scattered from a substance at certain wavelengths, incident angles, and polarization angles.</ncicp:def-definition><ncicp:Definition_Review_Date>100527</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>light scattering spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1712
preferred name: light scattering spectroscopy

wave
type: Class
subclass of: process
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A disturbance which carries energy radiated from a source and which propagates through space (vacuum or space occupied by a medium) and time.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>wikipedia (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1713
preferred name: wave

electromagnetic wave
type: Class
subclass of: wave
subclass of: Restriction
  on property: part of
  some values from: electromagnetic radiation
subclass of: Restriction
  on property: realizes
  some values from: light energy
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A wave which does not require a medium to travel, and hence can travel through vacuum. The wave consists of vibrating electric and magnetic fields that move at right angles to each other and to the direction of wave motion. The electric and magnetic fields are produced by the acceleration of charged particles.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://library.thinkquest.org/10796/ch8/ch8.htm (June 3, 2010), http://www.physicsclassroom.com/Class/waves/u10l1c.cfm (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>electromagnetic wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: E-M wave
synonym: EM wave
description: Electromagnetic waves are characterized by any of the three physical properties: frequency, wavelength or quantum (photon) energy. Frequency of a wave is defined as the ratio of the speed of light (in vacuum) to wavelength of the wave. The quantum energy is defined as the product of the Planck's constant and the wave frequency. The range of all possible frequencies or wavelengths or energies of an electromagnetic wave is called the electromagnetic spectrum. (reference: wikipedia)
code: NPO_1714
preferred name: electromagnetic wave

mechanical wave
type: Class
subclass of: wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A wave which requires a medium (e.g., air, water, solid) to travel for transmitting energy from one location to another, with no net displacement of the particles in the medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://library.thinkquest.org/10796/ch8/ch8.htm (June 3, 2010); http://www.visionlearning.com (June 8, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mechanical wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1715
preferred name: mechanical wave

gamma-ray wave
type: Class
subclass of: electromagnetic wave
subclass of: Restriction
  on property: part of
  some values from: gamma radiation
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths shorter than 0.001 nm, frequencies greater than 100 EHz (1 EHz = 10^18 Hz), and energies greater than 1.24 MeV.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://hyperphysics.phy-astr.gsu.edu/hbase/ems3.html#c5 (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>gamma-ray wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1716
preferred name: gamma-ray wave

x-ray wave
type: Class
subclass of: electromagnetic wave
subclass of: Restriction
  on property: part of
  some values from: x-ray radiation
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths between 10 nm and 0.001 nm, frequencies between 30 PHz and 100 EHz (1 PHz - 10^15 Hz, 1 EHz = 10^18 Hz), and energies between 124 eV and 1.24 MeV. An X-ray wave has wavelength shorter than that of an ultraviolet wave and longer than that of a gamma-ray wave</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://hyperphysics.phy-astr.gsu.edu/hbase/ems3.html#c4 (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>x-ray wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1717
preferred name: x-ray wave

ultraviolet wave
type: Class
subclass of: electromagnetic wave
subclass of: Restriction
  on property: realizes
  some values from: ultraviolet light energy
subclass of: Restriction
  on property: part of
  some values from: ultraviolet radiation
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths between 400 nm and 10 nm, frequencies between 300 THz and 750 THz (1 THz = 10^12 Hz), and energies between 3.1 eV and 124 eV. An ultraviolet wave has a wavelength shorter than that of a visible light wave, but longer than that of an x-ray wave.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://hyperphysics.phy-astr.gsu.edu/hbase/ems3.html#c4 (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ultraviolet wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1718
synonym: UV wave
preferred name: ultraviolet wave

visible light wave
type: Class
subclass of: electromagnetic wave
subclass of: Restriction
  on property: part of
  some values from: visible light radiation
subclass of: Restriction
  on property: realizes
  some values from: visible light energy
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths between 750 nm and 400 nm, frequencies between 400 THz and 750 THz (1 THz = 10^12 Hz), and energies between 1.65 eV and 3.1 eV. A visible light wave has a wavelength longer than that of an ultraviolet wave, and shorter than that of an infrared wave.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://hyperphysics.phy-astr.gsu.edu/hbase/ems3.html#c2 (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>visible light wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1719
preferred name: visible light wave

infrared wave
type: Class
subclass of: electromagnetic wave
subclass of: Restriction
  on property: part of
  some values from: infrared radiation
subclass of: Restriction
  on property: realizes
  some values from: infrared light energy
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths between 1 mm and 750 nm, frequencies between 300 GHz and 40 THz (1 GHz = 10^9 Hz, 1 THz = 10^12 Hz), and energies between 0.00124 eV and 1.65 eV. An infrared wave has a wavelength longer than that of a visible light wave, and shorter than that of a microwave.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://hyperphysics.phy-astr.gsu.edu/hbase/ems3.html#c1 (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>infrared wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: IR wave
code: NPO_1720
preferred name: infrared wave

far-infrared wave
type: Class
subclass of: infrared wave
subclass of: Restriction
  on property: realizes
  some values from: far-infrared light energy
subclass of: Restriction
  on property: part of
  some values from: far-infrared radiation
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared wave which has wavelengths between 1 mm and 10 um, frequencies between 300 GHz and 30 THz (1 GHz = 10^9 Hz, 1 THz = 10^12 Hz), and energies between 0.00124 eV and 0.124 eV.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>far-infrared wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: FIR wave
code: NPO_1721
preferred name: far-infrared wave

mid-infrared wave
type: Class
subclass of: infrared wave
subclass of: Restriction
  on property: part of
  some values from: mid-infrared radiation
subclass of: Restriction
  on property: realizes
  some values from: mid-infrared light energy
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared wave which has wavelengths between 10 um and 2.5 um, frequencies between 30 THz and 120 THz (1 THz = 10^12 Hz), and energies between 0.124 eV and 0.5 eV.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mid-infrared wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: MIR wave
code: NPO_1722
preferred name: mid-infrared wave

near-infrared wave
type: Class
subclass of: infrared wave
subclass of: Restriction
  on property: part of
  some values from: near-infrared radiation
subclass of: Restriction
  on property: realizes
  some values from: near-infrared light energy
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared wave which has wavelengths between 2.5 um and 750 nm, frequencies between 120 THz and 400 THz (1 THz = 10^12 Hz), and energies between 0.5 eV and 1.65 eV.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>near-infrared wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: NIR wave
code: NPO_1723
preferred name: near-infrared wave

microwave
type: Class
subclass of: electromagnetic wave
subclass of: Restriction
  on property: part of
  some values from: microwave radiation
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths between 30 cm and 1 mm, frequencies between 1 GHz and 300 GHz (1 GHz = 10^9 Hz), and energies between 4.1 ueV and 1.24 meV. A microwave has a wavelength longer than that of an infrared wave, but shorter than that of a radiowave.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://physics.info/em-spectrum (June 3, 2010), wikipedia (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>microwave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1724
preferred name: microwave

radiowave
type: Class
subclass of: electromagnetic wave
subclass of: Restriction
  on property: part of
  some values from: radiowave radiation
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths longer than 30 cm, frequencies less than 1 GHz (1 GHz = 10^9 Hz). and energies less than 4.1 ueV.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>radiowave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1725
preferred name: radiowave

transverse wave
type: Class
subclass of: mechanical wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A mechanical wave in which the particles of the medium move back and forth in a direction perpendicular to the direction in which the wave moves and transports energy.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>transverse wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1726
preferred name: transverse wave

longitudinal wave
type: Class
subclass of: mechanical wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A mechanical wave in which particles of the medium move back and forth in a direction parallel to the direction in which the wave moves and transports energy.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>longitudinal wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1727
preferred name: longitudinal wave

sound wave
type: Class
subclass of: longitudinal wave
subclass of: Restriction
  on property: part of
  some values from: sound radiation
subclass of: Restriction
  on property: realizes
  some values from: sound energy
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A longitudinal wave which transports energy (sound energy) produced by a vibrating object through a medium in which the back and forth motions of the particles result in regions of high (compression) and low pressure (rarefactions) in the medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>sound wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1728
synonym: acoustic wave
preferred name: sound wave

audible sound wave
type: Class
subclass of: sound wave
subclass of: Restriction
  on property: realizes
  some values from: audible sound energy
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A sound wave which is transmitted through air causing a sinusoidal pressure variation in the air at a frequency within the human audible range, i.e., approximately between 20 Hz and 20 kHz.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>audible sound wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1729
preferred name: audible sound wave

nitrogen
type: Class
subclass of: element
disjoint with: meitnerium
disjoint with: lawrencium
disjoint with: einsteinium
disjoint with: beryllium
disjoint with: mercury
disjoint with: boron
disjoint with: dysprosium
disjoint with: radon
disjoint with: magnesium
disjoint with: calcium
disjoint with: protactinium
disjoint with: fluorine
disjoint with: neodymium
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc

ultrasound wave
type: Class
subclass of: sound wave
subclass of: Restriction
  on property: realizes
  some values from: ultrasound energy
subclass of: Restriction
  on property: part of
  some values from: ultrasound radiation
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A sound wave which has frequencies above 20 kHz (upper limit of the human audible frequency range).</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ultrasound wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1730
synonym: ultrasonic wave
preferred name: ultrasound wave

radiation
type: Class
subclass of: process
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A process in which energy emitted by a material source travels in the form of waves, rays, or sub-atomic particles, through a material medium or through vacuum, to be ultimately absorbed by another material.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1731
preferred name: radiation

electromagnetic radiation
type: Class
subclass of: radiation
subclass of: Restriction
  on property: has part
  some values from: electromagnetic wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A radiation which consists of waves of energy associated with electric and magnetic fields produced by the acceleration of electric charges.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>electromagnetic radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: E-M radiation
synonym: EMR
code: NPO_1732
preferred name: electromagnetic radiation

gamma radiation
type: Class
subclass of: electromagnetic radiation
subclass of: Restriction
  on property: has part
  some values from: gamma-ray wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies greater than 100 EHz (1 EHz = 10^18 Hz), and with wavelengths shorter than 0.001 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>gamma radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1733
preferred name: gamma radiation
synonym: gamma ray
synonym: gamma ray radiation

x-ray radiation
type: Class
subclass of: electromagnetic radiation
subclass of: Restriction
  on property: has part
  some values from: x-ray wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies between 30 PHz and 100 EHz (1 PHz = 10^15 Hz, 1 EHz = 10^18 Hz), and with wavelengths between 10 nm and 0.001 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>x-ray radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1734
synonym: x-ray
preferred name: x-ray radiation

ultraviolet radiation
type: Class
subclass of: electromagnetic radiation
subclass of: Restriction
  on property: has part
  some values from: ultraviolet wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies between 300 THz and 750 THz (1 THz = 10^12 Hz), and with wavelengths between 400 nm and 10 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ultraviolet radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1735
synonym: UV radiation
preferred name: ultraviolet radiation

visible light radiation
type: Class
subclass of: electromagnetic radiation
subclass of: Restriction
  on property: has part
  some values from: visible light wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which can be detected by the human eye, and it consists of waves with frequencies between 400 THz and 750 THz (1 THz = 10^12 Hz), and with wavelengths between 750 nm and 400 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>visible light radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1736
preferred name: visible light radiation

infrared radiation
type: Class
subclass of: electromagnetic radiation
subclass of: Restriction
  on property: has part
  some values from: infrared wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies between 300 GHz and 400 THz (1 GHz = 10^9 Hz, 1 THz = 10^12 Hz), and with wavelengths between 1 mm and 750 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>infrared radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1737
preferred name: infrared radiation

far-infrared radiation
type: Class
subclass of: infrared radiation
subclass of: Restriction
  on property: has part
  some values from: far-infrared wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared radiation which consists of waves with frequencies between 300 GHz and 30 THz (1 GHz = 10^9 Hz, 1 THz = 10^12 Hz), and with wavelengths between 1 mm and 10 um.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>far-infrared radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: FIR radiation
code: NPO_1738
preferred name: far-infrared radiation

mid-infrared radiation
type: Class
subclass of: infrared radiation
subclass of: Restriction
  on property: has part
  some values from: mid-infrared wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared radiation which consists of waves with frequencies between 30 THz and 120 THz (1THz = 10^12 Hz ), and with wavelengths between 10 um and 2.5 um.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mid-infrared radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: MIR radiation
code: NPO_1739
preferred name: mid-infrared radiation

functional group
type: Class
subclass of: group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A group which is a specific atom or group of atoms attached to the carbon backbone of an organic molecule, and it is responsible for characteristic reactions of the molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>functional group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: Each functional group has its characteristic reactivity, which may be modified by its position within the molecule or by the presence of other neighbouring functional groups. (source: Functional Group Chemistry by James R. Hanson and Eddie Abel, published by Wiley, John & Sons, Incorporate 2002)
code: NPO_174
synonym: characteristic group
preferred name: functional group

near-infrared radiation
type: Class
subclass of: infrared radiation
subclass of: Restriction
  on property: has part
  some values from: near-infrared wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared radiation which consists of waves with frequencies between 120 THz and 400 THz (1 THz = 10^12 Hz), and with wavelengths between 2.5 um and 750 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>near-infrared radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: NIR radiation
code: NPO_1740
preferred name: near-infrared radiation

microwave radiation
type: Class
subclass of: electromagnetic radiation
subclass of: Restriction
  on property: has part
  some values from: microwave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies between 1 GHz and 300 GHz (1 GHz = 10^9 Hz), and with wavelengths between 30 cm and 1 mm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>microwave radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1741
preferred name: microwave radiation

radiowave radiation
type: Class
subclass of: electromagnetic radiation
subclass of: Restriction
  on property: has part
  some values from: radiowave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies less than 1 GHz (1 GHz = 10^9 Hz), and with wavelengths longer than 30 cm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>radiowave radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1742
preferred name: radiowave radiation

sound radiation
type: Class
subclass of: radiation
subclass of: Restriction
  on property: has part
  some values from: sound wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A radiation which consists of waves that transmit sound energy produced from a source, and the waves travel through a medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>sound radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1743
preferred name: sound radiation

ultrasound radiation
type: Class
subclass of: sound radiation
subclass of: Restriction
  on property: has part
  some values from: ultrasound wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A sound radiation which consists of waves that transmit sound energy at frequencies above 20 kHz (upper limit of the human audible frequency range)</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ultrasound radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1744
preferred name: ultrasound radiation

energy
type: Class
subclass of: realizable_entity
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity which is the capacity to do work or to exert force over a distance.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1745
preferred name: energy

kinetic energy
type: Class
subclass of: energy
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Energy associated with a moving object by virtue of its motion.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>kinetic energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1746
preferred name: kinetic energy

potential energy
type: Class
subclass of: energy
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Energy which is stored in an object, and that can be converted into some form of kinetic energy.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>potential energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1747
preferred name: potential energy
synonym: stored energy

electrical energy
type: Class
subclass of: kinetic energy
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Kinetic energy which is associated with moving electrons.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>electrical energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1748
preferred name: electrical energy
synonym: electricity

heat energy
type: Class
subclass of: kinetic energy
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Kinetic energy which is associated with randomly moving atoms or molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>heat energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1749
synonym: heat
preferred name: heat energy
synonym: thermal energy

arylthioether linkage between thiol and fluorobenzene derivative
type: Class
subclass of: arylthioether linkage
subclass of: Restriction
  on property: derives from
  some values from: fluorobenzene group
subclass of: Restriction
  on property: derives from
  some values from: sulfhydryl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An arylthioether linkage which is formed between a thiol and a fluorobenzene derivative, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>arylthioether linkage between thiol and fluorobenzene derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_175
preferred name: arylthioether linkage between thiol and fluorobenzene derivative

light energy
type: Class
subclass of: kinetic energy
subclass of: Restriction
  on property: is realized in
  some values from: electromagnetic wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Kinetic energy which is associated with the motion of electromagnetic waves produced by the acceleration of electric charges.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>light energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1750
synonym: electromagnetic energy
synonym: light
preferred name: light energy

infrared light energy
type: Class
subclass of: light energy
subclass of: Restriction
  on property: is realized in
  some values from: infrared wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Light energy which is associated with the motion of infrared waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>infrared light energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1751
synonym: infrared light
preferred name: infrared light energy

far-infrared light energy
type: Class
subclass of: infrared light energy
subclass of: Restriction
  on property: is realized in
  some values from: far-infrared wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Light energy which is associated with the motion of far-infrared waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>far-infrared light energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1752
synonym: far-infrared light
preferred name: far-infrared light energy

mid-infrared light energy
type: Class
subclass of: infrared light energy
subclass of: Restriction
  on property: is realized in
  some values from: mid-infrared wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Infrared light energy which is asscoated with the motion of mid-infrared waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mid-infrared light energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1753
synonym: mid-infrared light
preferred name: mid-infrared light energy

near-infrared light energy
type: Class
subclass of: infrared light energy
subclass of: Restriction
  on property: is realized in
  some values from: near-infrared wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Infrared light energy which is associated with the motion of near-infrared light waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>near-infrared light energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1754
synonym: near-infrared light
preferred name: near-infrared light energy

ultraviolet light energy
type: Class
subclass of: light energy
subclass of: Restriction
  on property: is realized in
  some values from: ultraviolet wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Light energy which is associated with the motion of ultraviolet waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ultraviolet light energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1755
synonym: UV light
synonym: ultraviolet light
preferred name: ultraviolet light energy

visible light energy
type: Class
subclass of: light energy
subclass of: Restriction
  on property: is realized in
  some values from: visible light wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Light energy which is associated with the motion of visible light waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>visible light energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1756
synonym: visible light
preferred name: visible light energy

sound energy
type: Class
subclass of: kinetic energy
subclass of: Restriction
  on property: is realized in
  some values from: sound wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Kinetic energy which is produced by the vibrations of an object, and transported by disturbances (sound waves) traveling through a medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>sound energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1757
synonym: sound
preferred name: sound energy

audible sound energy
type: Class
subclass of: sound energy
subclass of: Restriction
  on property: is realized in
  some values from: audible sound wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Sound energy which is carried by waves (audible sound waves) traveling at frequencies (between 20 Hz and 20 kHz) that can be detected by the human ear.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>audible sound energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1758
synonym: audible sound
preferred name: audible sound energy

ultrasound energy
type: Class
subclass of: sound energy
subclass of: Restriction
  on property: is realized in
  some values from: ultrasound wave
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Sound energy which is carried by waves (ultrasound waves) that travel at frequencies above the human audible range (above 20 kHz).</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ultrasound energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1759
synonym: ultrasonic sound
synonym: ultrasound
preferred name: ultrasound energy

stimulus of near-infrared light
type: Class
subclass of: stimulus of light
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by near-infrared light.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>stimulus of near-infrared light</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_176
preferred name: stimulus of near-infrared light

chemical energy
type: Class
subclass of: potential energy
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Potential energy which is stored in the chemical bonds of molecules, and which is released as heat energy in a chemical reaction.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>chemical energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1760
preferred name: chemical energy

nuclear energy
type: Class
subclass of: potential energy
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Potential energy which is stored in interactions between the particles in the atomic nucleus.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>nuclear energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1761
preferred name: nuclear energy

cell counting technique
type: Class
subclass of: technique
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A technique which is used for counting cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100614</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cell counting technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1762
preferred name: cell counting technique

fluorescent cell counting technique
type: Class
subclass of: cell counting technique
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cell counting technique which uses fluorescence for counting the cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100614</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>fluorescent cell counting technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1763
preferred name: fluorescent cell counting technique

confocal laser scanning microscopy
type: Class
subclass of: optical microscopy
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A fluorescence microscopic technique which uses scanning laser light to excite fluorescent dyes within a thick sample, such as a biofilm. The image is collected in two dimensions and several images can be combined in an image stack to produce a cross sectional image through a sample or to create a three-dimensional rendering of the sample. This technique is particularly useful for imaging the positioning of biological structures within a three-dimensional space.</ncicp:def-definition><ncicp:Definition_Review_Date>100614</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.nature.com/nrd/journal/v2/n2/glossary/nrd1008_glossary.html</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>confocal laser scanning microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: CLSM
code: NPO_1764
preferred name: confocal laser scanning microscopy

hemocytometer
type: Class
subclass of: instrument
subclass of: Restriction
  on property: has application
  some values from: cell counting technique
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which consists of a thick glass slide that has a chamber with a defined volume, etched with a precisely ruled grid and is used to quantify cells or cell-sized particles in suspension.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>NCI Thesaurus</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>hemocytometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C78807
code: NPO_1765
preferred name: hemocytometer

dynamic light scattering instrument
type: Class
subclass of: instrument
subclass of: Restriction
  on property: has application
  some values from: dynamic light scattering
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to perform dynamic light scattering technique.</ncicp:def-definition><ncicp:Definition_Review_Date>100616</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>dynamic light scattering instrument</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: DLS instrument
code: NPO_1766
preferred name: dynamic light scattering instrument

phase analysis light scattering instrument
type: Class
subclass of: instrument
subclass of: Restriction
  on property: has application
  some values from: phase analysis light scattering
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to perform phase analysis light scattering technique.</ncicp:def-definition><ncicp:Definition_Review_Date>100617</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>phase analysis light scattering instrument</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1767
synonym: PALS instrument
preferred name: phase analysis light scattering instrument

environmental transmission electron microscope
type: Class
subclass of: transmission electron microscope
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A transmission electron microscope which is designed to allow the scientist to both introduce various gases into and change the temperature of the specimen/sample environment. Reactions of the sample with its environment can then be directly recorded.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:def-source>NCI</ncicp:def-source><ncicp:attr>NCIT</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>environmental transmission electron microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: EC-TEM
synonym: ETEM
DB xref ID: NCIT: C78860
code: NPO_1768
synonym: environmental cell-transmission electron microscope
preferred name: environmental transmission electron microscope

flow cytometer
type: Class
subclass of: instrument
subclass of: Restriction
  on property: has application
  some values from: flow cytometry
subclass of: Restriction
  on property: has application
  some values from: cell counting technique
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to count and sort microscopic particles suspended in a buffer. This instrument consists of a flow cell, at least one lamp or laser, a variable number of emission detectors or photomultipliers, a system that converts analog signals to digital, and a computer to run the system and collect and analyze the data output.</ncicp:def-definition><ncicp:Definition_Review_Date>100616</ncicp:Definition_Review_Date><ncicp:def-source>NCI</ncicp:def-source><ncicp:attr>NCIT</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>flow cytometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C78806
code: NPO_1769
preferred name: flow cytometer

series element
type: Class
subclass of: periodic table element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element whose physical and chemical characteristics vary progressively within a series.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>series element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_177
preferred name: series element

analytical balance
type: Class
subclass of: instrument
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to determine the mass of a sample with a high degree of precision.</ncicp:def-definition><ncicp:Definition_Review_Date>100616</ncicp:Definition_Review_Date><ncicp:def-source>NCI</ncicp:def-source><ncicp:attr>NCIT</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>analytical balance</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C80370
code: NPO_1770
preferred name: analytical balance

coulter counter
type: Class
subclass of: instrument
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>An instrument which is used to measure changes in the electrical resistance of an electrolyte solution produced by suspended nonconductive particles. Changes in resistance determine both the concentraion and size distribution of the particles.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>coulter counter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C62330
code: NPO_1771
preferred name: coulter counter
synonym: particle count analyzer
synonym: particle count and size analyzer
synonym: particle counter
synonym: particle size analyzer

photometer
type: Class
subclass of: instrument
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to measure the intensity of visible light.</ncicp:def-definition><ncicp:Definition_Review_Date>100617</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>NCIT</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>photometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C80371
code: NPO_1772
preferred name: photometer

spectrophotometer
type: Class
subclass of: photometer
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A photometer which measures the intensity of visible light as a function of wavelength.</ncicp:def-definition><ncicp:Definition_Review_Date>100617</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>spectrophotometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C62333
code: NPO_1773
synonym: spectrometer
preferred name: spectrophotometer

X-ray photoelectron spectrometer
type: Class
subclass of: spectrophotometer
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectrometer which is used to determine the energy of photoelectrons emitted from the core orbitals of the elements within a few nm from the surface of a material, by irradiating the material surface with soft monochromatic X-rays.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>X-ray photoelectron spectrometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1774
preferred name: X-ray photoelectron spectrometer

zeta potential analyzer
type: Class
subclass of: instrument
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>An instrument which is used to measure zeta potential.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>zeta potential analyzer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1775
preferred name: zeta potential analyzer

capillary electrophoresis instrument
type: Class
subclass of: instrument
subclass of: Restriction
  on property: has application
  some values from: capillary electrophoresis
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to perform capillary electrophoresis.</ncicp:def-definition><ncicp:Definition_Review_Date>100617</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>capillary electrophoresis instrument</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1776
preferred name: capillary electrophoresis instrument

energy dispersive spectrometer
type: Class
subclass of: spectrophotometer
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A spectrometer which focuss high energy electromagnetic radiation toward a sample and measures the X-rays emitted from the sample.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>energy dispersive spectrometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: EDS
synonym: EDX
DB xref ID: NCIT: C78805
code: NPO_1777
synonym: energy dispersive X-ray spectrometer
preferred name: energy dispersive spectrometer

gel filtration column
type: Class
subclass of: instrument
subclass of: Restriction
  on property: has application
  some values from: size-exclusion chromatography
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is a column in which gel particles in bead form are packed to form a separation bed through which a solution containing molecules /particles and an eluant (a buffer solution) are passed for separating the molecules/particles according to differences in their sizes.</ncicp:def-definition><ncicp:Definition_Review_Date>100616</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.scribd.com/doc/6941835/gel-filtration (June 16, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>gel filtration column</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1778
preferred name: gel filtration column

datum value
type: Class
subclass of: generically_dependent_continuant
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A value which is given for a variable or parameter in a data record.</ncicp:def-definition><ncicp:Definition_Review_Date>100618</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>datum value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1779
preferred name: datum value

meitnerium
type: Class
subclass of: element
disjoint with: lawrencium
disjoint with: einsteinium
disjoint with: beryllium
disjoint with: mercury
disjoint with: boron
disjoint with: dysprosium
disjoint with: radon
disjoint with: magnesium
disjoint with: calcium
disjoint with: protactinium
disjoint with: fluorine
disjoint with: neodymium
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon

number
type: Class
subclass of: generically_dependent_continuant
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A generically dependent continuant which can be represented using different types of numerals, and which is used for counting, measuring or computing a quantity, or for identification.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>number</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1780
preferred name: number

symbol
type: Class
subclass of: generically_dependent_continuant
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A generically dependent continuant which is used for or regarded as representing something else.</ncicp:def-definition><ncicp:Definition_Review_Date>100618</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://dictionary.reference.com/browse/symbol (June 18, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>symbol</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1781
preferred name: symbol

alphanumeral
type: Class
subclass of: symbol
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A symbol which represents a string of letters and numbers.</ncicp:def-definition><ncicp:Definition_Review_Date>100618</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>alphanumeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1782
preferred name: alphanumeral

numeral
type: Class
subclass of: symbol
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A symbol which denotes or represents a number in a language.</ncicp:def-definition><ncicp:Definition_Review_Date>100618</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1783
preferred name: numeral

arabic numeral
type: Class
subclass of: numeral
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A numeral which is one of the following: 1, 2, 3, 4, 5, 6, 7, 8, 9, and 0.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>arabic numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1784
preferred name: arabic numeral

english numeral
type: Class
subclass of: numeral
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A numeral which denotes numbers as words used in the english language.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>english numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1785
preferred name: english numeral

cardinal numeral
type: Class
subclass of: english numeral
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An english numeral which is basic in form, and which is used in counting and expressing how many objects are referred to. (Examples: one, two, three, one hundred, etc.)</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.sil.org/linguistics/GlossaryOfLinguisticTerms/WhatIsACardinalNumeral.htm (June 21, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cardinal numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1786
preferred name: cardinal numeral

distributive numeral
type: Class
subclass of: english numeral
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An english numeral which expresses a group of the number specified. (examples: by the dozen, in pairs)</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.sil.org/linguistics/GlossaryOfLinguisticTerms/WhatIsADistributiveNumeral.htm (June 21, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>distributive numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1787
preferred name: distributive numeral

multiplicative numeral
type: Class
subclass of: english numeral
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An english numeral which expresses how many fold or how many times. (Examples: once, twice, thrice, ...)</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.sil.org/linguistics/GlossaryOfLinguisticTerms/WhatIsMultiplicativeNumeral.htm (June 21, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>multiplicative numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1788
preferred name: multiplicative numeral

ordinal numeral
type: Class
subclass of: english numeral
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An english numeral which is used to designate positions in a sequence. (Examples: first, second, third, etc.)</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ordinal numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1789
preferred name: ordinal numeral

atom
type: Class
equivalent class: Class
  intersection of: Restriction
    on property: is integral part of
    some values from: element
  intersection of: Restriction
    on property: is integral part of
    all values from: element
subclass of: chemical entity
definition: <ncicp:ComplexDefinition><ncicp:def-definition>An atom is the smallest particle that retains all the chemical properties of a given element.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_179
preferred name: atom

partitive numeral
type: Class
subclass of: english numeral
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An english numeral which is used to express a fraction. (Examples: one-half, one-third, etc.)</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>partitive numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1790
preferred name: partitive numeral

alphanumeric number
type: Class
subclass of: number
subclass of: Restriction
  on property: denoted by
  some values from: alphanumeral
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A number which is denoted by alphanumerals.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>alphanumeric number</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1791
preferred name: alphanumeric number

numeric number
type: Class
subclass of: number
subclass of: Restriction
  on property: denoted by
  some values from: arabic numeral
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A number which is denoted by arabic numerals.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>numeric number</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1792
preferred name: numeric number

quantitative value
type: Class
subclass of: datum value
subclass of: Restriction
  on property: has part
  some values from: numeric number
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A datum value which is expressed in numbers, and which is measured, assigned, or computed.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>quantitative value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1793
preferred name: quantitative value

qualitative value
type: Class
subclass of: datum value
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A datum value which is non-numerical measure or estimate of something.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>qualitative value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1794
preferred name: qualitative value

computed value
type: Class
subclass of: quantitative value
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value which is obtained by computations or calculations.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>computed value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1795
synonym: calculated value
preferred name: computed value

counted value
type: Class
subclass of: quantitative value
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value which is obtained by counting.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>counted value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1796
preferred name: counted value

statistical measure
type: Class
subclass of: computed value
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A computed value which is a summary of the individual quantitative variable values for the statistical units in a specific group (study domains).</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://stats.oecd.org/glossary</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>statistical measure</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1797
preferred name: statistical measure

measure of variability
type: Class
subclass of: statistical measure
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A statistical measure which describes the spread in a data set of numerical values for a quantitative variable.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>measure of variability</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1798
preferred name: measure of variability

measure of central tendency
type: Class
subclass of: statistical measure
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A statistical measure which is a meaure of the middle or expected value of a data set.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>measure of central tendency</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1799
preferred name: measure of central tendency

fiat dendrimer part
type: Class
equivalent class: Class
  intersection of: fiat material part
  intersection of: Restriction
    on property: part of
    some values from: dendrimer
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fiat part of a dendrimer.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fiat dendrimer part</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_180
preferred name: fiat dendrimer part

mean
type: Class
subclass of: measure of central tendency
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of central tendency which is the sum of all the numerical values in a data set divided by the numer of numerical values.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mean</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1800
synonym: average
synonym: average value
preferred name: mean
synonym: mean value

median
type: Class
subclass of: measure of central tendency
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of central tendency which is the middle value of a distribution of numerical values.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>median</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1801
preferred name: median

mode
type: Class
subclass of: measure of central tendency
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of central tendency which is the most frequently occurring value in a set of numerical values.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mode</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1802
preferred name: mode

variance
type: Class
subclass of: measure of variability
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of variability which is the average of the square of the difference between the numerical values and the mean in a data set.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>variance</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1803
preferred name: variance

standard deviation
type: Class
subclass of: measure of variability
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of variability which is the square root of variance.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>standard deviation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1804
preferred name: standard deviation

measured value
type: Class
subclass of: quantitative value
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value which is measured using an instrument.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>measured value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1805
preferred name: measured value

temperature value
type: Class
subclass of: quantitative value
subclass of: Restriction
  on property: measure of
  some values from: temperature
subclass of: Restriction
  on property: has unit of measure
  some values from: temperature unit
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of temperature which is measured or calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100622</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>temperature value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1806
preferred name: temperature value

size value
type: Class
equivalent class: Class
  intersection of: quantitative value
  intersection of: Restriction
    on property: measure of
    some values from: Class
      union of: tumor size
      union of: particle size
      union of: size
subclass of: Restriction
  on property: has unit of measure
  some values from: Class
    union of: length unit
    union of: area unit
    union of: volume unit
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of size which is measured or calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>size value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1807
preferred name: size value

core composition
type: Class
equivalent class: Class
  intersection of: chemical composition
  intersection of: Restriction
    on property: quality of
    some values from: core
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Composition which refers to the types and amounts of chemical components in the core of a material entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>core composition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1808
preferred name: core composition

semiconductor
type: Class
subclass of: solid
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A solid substance which has a conductivity between that of an insulator and that of a conductor.</ncicp:def-definition><ncicp:Definition_Review_Date>100622</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>semiconductor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1809
preferred name: semiconductor

carbonyl-reactive and sulfhydryl-reactive crosslinker
type: Class
subclass of: heterobifunctional crosslinker
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A heterobifunctional crosslinker, which has a carbonyl-reactive group at one end and a sulfhydryl-reactive group at the other end.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carbonyl-reactive and sulfhydryl-reactive crosslinker</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_181
preferred name: carbonyl-reactive and sulfhydryl-reactive crosslinker

hollow
type: Class
subclass of: independent specific individual quality
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality which indicates the presence of a hole or empty space within a material entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>hollow</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1810
preferred name: hollow

surface composition
type: Class
equivalent class: Class
  intersection of: chemical composition
  intersection of: Restriction
    on property: quality of
    some values from: material boundary
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Composition which refers to the types and amounts of chemical components on the surface of a material entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface composition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1811
preferred name: surface composition

surface charge
type: Class
equivalent class: Class
  intersection of: electric charge
  intersection of: Restriction
    on property: quality of
    some values from: material boundary
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electric charge which is the net charge present on the surface of a material entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface charge</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1812
preferred name: surface charge

body weight value
type: Class
subclass of: quantitative value
subclass of: Restriction
  on property: measure of
  some values from: body weight
subclass of: Restriction
  on property: has unit of measure
  some values from: Class
    union of: kilogram
    union of: gram
    union of: milligram
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of body weight which is measured.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>body weight value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1813
preferred name: body weight value

pH value
type: Class
subclass of: quantitative value
subclass of: Restriction
  on property: has unit of measure
  some values from: dimensionless unit
subclass of: Restriction
  on property: measure of
  some values from: Class
    union of: acidity
    union of: pH
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A quantitative value of pH which is measured or calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>pH value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1814
preferred name: pH value

zeta potential value
type: Class
subclass of: quantitative value
subclass of: Restriction
  on property: value specified at
  some values from: pH value
subclass of: Restriction
  on property: measure of
  some values from: zeta potential
subclass of: Restriction
  on property: has unit of measure
  some values from: millivolt
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of zeta potential which is measured or calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>zeta potential value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1815
preferred name: zeta potential value

percent cell viability
type: Class
subclass of: quantitative value
subclass of: Restriction
  on property: has unit of measure
  some values from: percent
subclass of: Restriction
  on property: measure of
  some values from: cell viability
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of cell viability which is measured or calculated in percentage units.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>percent cell viability</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1816
preferred name: percent cell viability

time value
type: Class
subclass of: quantitative value
subclass of: Restriction
  on property: has unit of measure
  some values from: time unit
subclass of: Restriction
  on property: measure of
  some values from: Class
    union of: time quality
    union of: connected_temporal_region
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of time which is measured or calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>time value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1817
preferred name: time value

duration
type: Class
subclass of: temporal_interval
subclass of: Restriction
  on property: has unit of measure
  some values from: time unit
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A temporal interval which is the time during which a process continues to occur.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>duration</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1818
preferred name: duration

time of exposure
type: Class
subclass of: duration
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>Duration in which a material entity is in contact with or exposed to something.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>time of exposure</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1819
preferred name: time of exposure

lawrencium
type: Class
subclass of: element
disjoint with: einsteinium
disjoint with: beryllium
disjoint with: mercury
disjoint with: boron
disjoint with: dysprosium
disjoint with: radon
disjoint with: magnesium
disjoint with: calcium
disjoint with: protactinium
disjoint with: fluorine
disjoint with: neodymium
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium

parts per billion
type: Class
subclass of: parts per notation
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A dimensionless concentration notation which denotes the amount of a given substance in a total amount of 1000, 000,000 regardless of the units of measure used as long as they are the same or 1 part in10^[9].</ncicp:def-definition><ncicp:Definition_Review_Date>100625</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>parts per billion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1820
preferred name: parts per billion
symbol: ppb

6-mercapto-hexanoic acid
type: Class
subclass of: carboxylic acid
subclass of: Restriction
  on property: has part
  some values from: sulfhydryl group
synonym: 6-MHA
preferred name: 6-mercapto-hexanoic acid
synonym: 6-mercaptohexanoic acid
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A carboxylic acid which is composed of six carbon atoms and a sulfhydryl group at the sixth carbon atom.</ncicp:def-definition><ncicp:Definition_Review_Date>100625</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>6-mercapto-hexanoic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: ?-mercaptohexonic acid
DB xref ID: CHEBI:226739
code: NPO_1821
symbol: OC(=O)CCCCCS

mean particle size
type: Class
subclass of: mean
subclass of: Restriction
  on property: measure of
  some values from: particle size
subclass of: Restriction
  on property: has unit of measure
  some values from: Class
    union of: length unit
    union of: area unit
    union of: volume unit
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A mean of all the individual particle size values in a collection of particles.</ncicp:def-definition><ncicp:Definition_Review_Date>100702</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mean particle size</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1822
synonym: average particle size
preferred name: mean particle size

coat composition
type: Class
equivalent class: Class
  intersection of: chemical composition
  intersection of: Restriction
    on property: quality of
    some values from: coat
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>Chemical composition of a coating layer on a material surface.</ncicp:def-definition><ncicp:Definition_Review_Date>100702</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>coat composition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1823
preferred name: coat composition
synonym: coating composition

shell composition
type: Class
equivalent class: Class
  intersection of: chemical composition
  intersection of: Restriction
    on property: quality of
    some values from: shell
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Chemical composition of a material layer surrounding the core.</ncicp:def-definition><ncicp:Definition_Review_Date>100702</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>shell composition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1824
preferred name: shell composition

test sample
type: Class
subclass of: sample
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A sample which is tested for determining its physical, chemical, and functional properties in an experiment.</ncicp:def-definition><ncicp:Definition_Review_Date>100714</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>test sample</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1825
synonym: experimental sample
preferred name: test sample

conjugated component
type: Class
subclass of: chemical component in nanoparticle formulation
subclass of: Restriction
  on property: part of
  some values from: attachment
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical component in a nanoparticle formulation, which is a nanoparticle or a molecule that is conjugated to another nanoparticle or molecule in the same formulation.</ncicp:def-definition><ncicp:Definition_Review_Date>100714</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>conjugated component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1826
preferred name: conjugated component

encapsulated component
type: Class
subclass of: chemical component in nanoparticle formulation
subclass of: Restriction
  on property: part of
  some values from: encapsulation
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical component in nanoparticle formulation which is a nanoparticle or a molecule that is fully enclosed within a nanoparticle's site that is fully bounded by the particle's constituting material.</ncicp:def-definition><ncicp:Definition_Review_Date>100714</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>encapsulated component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1827
preferred name: encapsulated component

entrapped component
type: Class
subclass of: chemical component in nanoparticle formulation
subclass of: Restriction
  on property: part of
  some values from: entrapment
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical component in nanoparticle formulation, which is a molecule or a nanoparticle that is trapped due to non-covalent interactions in a nanoparticle's site that is partially bounded by the particle's constituting material.</ncicp:def-definition><ncicp:Definition_Review_Date>100714</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>entrapped component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1828
preferred name: entrapped component

mean polydispersity index
type: Class
subclass of: mean
subclass of: Restriction
  on property: measure of
  some values from: polydispersity index
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A mean value calculated from the polydispersity indices of particle or polymeric samples of the same type.</ncicp:def-definition><ncicp:Definition_Review_Date>100727</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mean polydispersity index</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1829
preferred name: mean polydispersity index

fiber-optic nanosensor
type: Class
subclass of: nanosensor
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanosensor which is defined as a nanometer-scale measurement device that consists of a biologically or chemically sensitive layer, such as an immobilized receptor, antibody, or nucleic acid, that is covalently attached to an optical transducer. In the case of a receptor-based nanosensor, an interaction between the immobilized receptor and its substrate - the molecule it binds to - produces a perturbation that the optical transducer converts to an electrical signal via laser-induced fluorescence.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fiber-optic nanosensor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_183
preferred name: fiber-optic nanosensor

particle concentration
type: Class
subclass of: dependent specific individual quality
subclass of: Restriction
  on property: quality of
  some values from: nanoparticle component
subclass of: Restriction
  on property: has unit of measure
  some values from: mass density unit
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Concentration of particles dispersed in a medium or in solution.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>particle concentration</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1830
preferred name: particle concentration

solute
type: Class
subclass of: chemical substance by physical state
subclass of: Restriction
  on property: has role
  some values from: solute role
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A substance which dissolves in another substance (solvent) to form a solution.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>solute</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1832
preferred name: solute

solute role
type: Class
subclass of: role
subclass of: Restriction
  on property: role of
  some values from: solute
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A role inhering in a certain amount of a compound, which is realized when it is dissolved in a solvent.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>solute role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1833
preferred name: solute role

solvent role
type: Class
subclass of: role
subclass of: Restriction
  on property: role of
  some values from: solvent
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A role which inheres in a liquid compound, and it is realized when the liquid dissolves another substance (solute).</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>solvent role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1834
preferred name: solvent role

solution
type: Class
subclass of: mixture
subclass of: Restriction
  on property: has part
  some values from: solute
subclass of: Restriction
  on property: has part
  some values from: solvent
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A liquid mixture which is a homogenous mixture formed by dissolving a substance (solute) in a liquid (solvent).</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>solution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1835
preferred name: solution

buffer solution
type: Class
equivalent class: Class
  intersection of: aqueous solution
  intersection of: Restriction
    on property: has part
    some values from: buffer
subclass of: Restriction
  on property: has quality
  some values from: pH
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An aqueous solution which consists of a weak acid and its conjugate base or a weak base and its conjugate acid; and which resists any changes in its pH when a small amount of strong acid or base is added to it.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://en.wikipedia.org/wiki/Buffer_solution ( July 28, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>buffer solution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1836
preferred name: buffer solution

aqueous solution
type: Class
subclass of: solution
subclass of: Restriction
  on property: has quality
  some values from: aqueous
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: water
    intersection of: Restriction
      on property: has role
      some values from: solvent role
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A solution which contains water as the solvent.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>aqueous solution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1837
preferred name: aqueous solution

aqueous
type: Class
subclass of: independent specific individual quality
subclass of: Restriction
  on property: quality of
  some values from: aqueous solution
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality which inheres in a substance by virtue of it containing water as a solvent or a medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>aqueous</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1838
preferred name: aqueous

buffer
type: Class
subclass of: chemical substance by physical state
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A substance which is added to an acidic or basic solution, and then modifies its pH value to a new one and then maintains that pH.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>buffer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1839
preferred name: buffer

einsteinium
type: Class
subclass of: element
disjoint with: beryllium
disjoint with: mercury
disjoint with: boron
disjoint with: dysprosium
disjoint with: radon
disjoint with: magnesium
disjoint with: calcium
disjoint with: protactinium
disjoint with: fluorine
disjoint with: neodymium
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium

acid solution
type: Class
subclass of: aqueous solution
subclass of: Restriction
  on property: has quality
  some values from: acidic
subclass of: Restriction
  on property: has quality
  some values from: acidic pH
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>An aqueous solution which contains more hydrogen ions than hydroxyl ions.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>acid solution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1840
preferred name: acid solution
synonym: acidic solution

alkaline solution
type: Class
subclass of: aqueous solution
subclass of: Restriction
  on property: has quality
  some values from: basic pH
subclass of: Restriction
  on property: has quality
  some values from: alkaline
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An aqueous solution which contains more hydroxyl ions than hydrogen ions.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>alkaline solution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1841
preferred name: alkaline solution
synonym: basic solution

saline
type: Class
subclass of: aqueous solution
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: sodium chloride
    intersection of: Restriction
      on property: has role
      some values from: solute role
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An aqueous solution of sodium chloride.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>saline</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1842
preferred name: saline
synonym: saline solution

sodium chloride
type: Class
subclass of: salt
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A salt whcih is composed of sodium and chloride ions.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>sodium chloride</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1843
symbol: NaCl
preferred name: sodium chloride

isotonic
type: Class
subclass of: independent specific individual quality
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a solution by virtue of it having the same solute concentration as another solution.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>isotonic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1844
preferred name: isotonic

isotonic saline
type: Class
subclass of: saline
subclass of: Restriction
  on property: has quality
  some values from: isotonic
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A saline solution which has the same NaCl concentration as blood.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>isotonic saline</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1845
preferred name: isotonic saline
synonym: isotonic saline solution

phosphate buffer saline
type: Class
subclass of: isotonic saline
subclass of: Restriction
  on property: has part
  some values from: buffer
definition: <ncicp:ComplexDefinition><ncicp:def-definition>An isotonic saline solution which contains phosphate buffer.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>phosphate buffer saline</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1846
synonym: PBS
preferred name: phosphate buffer saline
synonym: phosphate buffer saline solution

distilled water
type: Class
subclass of: water
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Water which has been purified by distillation.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://encyclopedia.thefreedictionary.com (July 28, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>distilled water</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1847
preferred name: distilled water

deionized water
type: Class
subclass of: water
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Water which has been purified by ion exchange process, and lacks cations from sodium, calcium, iron, copper and anions such as chloride and bromide.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://encyclopedia.thefreedictionary.com (July 28, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>deionized water</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1848
preferred name: deionized water

polydispersity index value
type: Class
subclass of: quantitative value
subclass of: Restriction
  on property: has unit of measure
  some values from: weight ratio
subclass of: Restriction
  on property: measure of
  some values from: polydispersity index
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of polydispersity index, which is calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>polydispersity index value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1849
synonym: PDI value
preferred name: polydispersity index value

iodoacetyl compound
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: iodoacetyl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iodoacetyl compound is an organic compound which is characterized by the presence of an iodoacetyl group. It has the structure R-C(=O)-CH2-I, where R denotes an organic group or hydrogen atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>iodoacetyl compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_185
preferred name: iodoacetyl compound
synonym: iodoacetyl derivative

refractive index
type: Class
subclass of: realizable_entity
subclass of: Restriction
  on property: has unit of measure
  some values from: dimensionless unit
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A realizable entity, which is defined as the ratio of the speed of light in vacuum to that in a substance. It is a measure of the speed of light in the substance.</ncicp:def-definition><ncicp:Definition_Review_Date>130524</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>refractive index</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1850
synonym: index of refraction
preferred name: refractive index

refractive index value
type: Class
subclass of: quantitative value
subclass of: Restriction
  on property: has unit of measure
  some values from: dimensionless unit
subclass of: Restriction
  on property: measure of
  some values from: refractive index
subclass of: Restriction
  on property: value specified at
  some values from: temperature value
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of refractive index.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>refractive index value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1851
preferred name: refractive index value

viscosity
type: Class
subclass of: realizable_entity
subclass of: Restriction
  on property: property of
  some values from: Class
    union of: medium
    union of: biological fluid
    union of: fluid
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity inhering in a fluid, which is defined as the fluid's resistance to flow.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>viscosity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1852
preferred name: viscosity

medium
type: Class
subclass of: mixture
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A fluid which can hold other substances in solution or in suspension.</ncicp:def-definition><ncicp:Definition_Review_Date>100729</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>medium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1853
preferred name: medium

aqueous medum
type: Class
subclass of: medium
subclass of: Restriction
  on property: has quality
  some values from: liquid state
subclass of: Restriction
  on property: has part
  some values from: water
subclass of: Restriction
  on property: has quality
  some values from: aqueous
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A medium which contains water.</ncicp:def-definition><ncicp:Definition_Review_Date>100729</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>aqueous medum</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1854
preferred name: aqueous medum

solvent medium
type: Class
subclass of: medium
subclass of: Restriction
  on property: has quality
  some values from: liquid state
subclass of: Restriction
  on property: has role
  some values from: solvent role
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A medium which is used as a solvent to form a solution.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>solvent medium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1855
preferred name: solvent medium

suspending medium
type: Class
subclass of: medium
subclass of: Restriction
  on property: has quality
  some values from: liquid state
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A liquid medium which is used to suspend particles.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>suspending medium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1856
synonym: dispersing medium
preferred name: suspending medium

viscosity value
type: Class
subclass of: quantitative value
subclass of: Restriction
  on property: has unit of measure
  some values from: viscosity unit
subclass of: Restriction
  on property: measure of
  some values from: viscosity
subclass of: Restriction
  on property: value specified at
  some values from: temperature value
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of viscosity, which is measured or calculatd.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>viscosity value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1857
preferred name: viscosity value

viscosity unit
type: Class
subclass of: unit of measurement
subclass of: Restriction
  on property: unit of
  some values from: viscosity
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A unit of measure, which is a standard measure of the resistance of a fluid to deformation.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>viscosity unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1858
preferred name: viscosity unit

pascal second
type: Class
subclass of: viscosity unit
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A viscosity unit in standard international system, which is equal to 1 pascal second</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>pascal second</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
symbol: N s/m^[2]
code: NPO_1859
symbol: Pa s
symbol: kg / (m s)
preferred name: pascal second

gold quantum dot
type: Class
subclass of: quantum dot
subclass of: Restriction
  on property: has component part
  some values from: gold
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quantum dot composed of gold element</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gold quantum dot</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: Au quantum dot
code: NPO_186
preferred name: gold quantum dot

organic core
type: Class
equivalent class: Class
  intersection of: core
  intersection of: Restriction
    on property: has component part
    some values from: organic compound or molecule
subclass of: Restriction
  on property: has quality
  some values from: organic
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A core which is composed of organic molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>organic core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1860
preferred name: organic core

inorganic core
type: Class
subclass of: core
subclass of: Restriction
  on property: has component part
  some values from: inorganic molecular entity
subclass of: Restriction
  on property: has quality
  some values from: inorganic
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A core which is composed of inorganic molecular entities.</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>inorganic core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1861
preferred name: inorganic core

polymeric core
type: Class
subclass of: organic core
subclass of: Restriction
  on property: has component part
  some values from: polymer
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An organic core which is composed of polymers.</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>polymeric core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1862
synonym: polymer core
preferred name: polymeric core

metallic core
type: Class
equivalent class: Class
  intersection of: inorganic core
  intersection of: Restriction
    on property: has component part
    some values from: metal
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An inorganic core which is composed of one or more metals.</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>metallic core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1863
synonym: metal core
preferred name: metallic core

metal oxide core
type: Class
equivalent class: Class
  intersection of: inorganic core
  intersection of: Restriction
    on property: has component part
    some values from: metal oxide
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An inorganic core which is composed of metal oxide.</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>metal oxide core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1864
preferred name: metal oxide core

silica core
type: Class
subclass of: inorganic core
subclass of: Restriction
  on property: has component part
  some values from: silicon dioxide
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An inorganic core which is composed of silica (silicon dioxide).</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>silica core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1865
preferred name: silica core

semiconducting core
type: Class
equivalent class: Class
  intersection of: inorganic core
  intersection of: Restriction
    on property: has property
    some values from: semiconductivity
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An inorganic core which has semiconducting property.</ncicp:def-definition><ncicp:Definition_Review_Date>101007</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>semiconducting core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1866
preferred name: semiconducting core

semiconductivity
type: Class
subclass of: realizable_entity
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>An electrical conductivity which is intermediate between that of an insulator and a conductor.</ncicp:def-definition><ncicp:Definition_Review_Date>101007</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>semiconductivity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1867
preferred name: semiconductivity

inorganic shell
type: Class
equivalent class: Class
  intersection of: shell
  intersection of: Restriction
    on property: has component part
    some values from: inorganic molecular entity
subclass of: Restriction
  on property: has quality
  some values from: inorganic
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A shell which is made of inorganic material.</ncicp:def-definition><ncicp:Definition_Review_Date>101007</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>inorganic shell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1868
preferred name: inorganic shell

organic shell
type: Class
equivalent class: Class
  intersection of: shell
  intersection of: Restriction
    on property: has component part
    some values from: organic compound or molecule
subclass of: Restriction
  on property: has quality
  some values from: organic
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shell which is made of organic material.</ncicp:def-definition><ncicp:Definition_Review_Date>101007</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>organic shell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1869
preferred name: organic shell

sodium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 11
disjoint with: lanthanum atom
disjoint with: francium atom
disjoint with: caesium atom
disjoint with: nickel atom
disjoint with: fluorine atom
disjoint with: niobium atom
disjoint with: neon atom
disjoint with: promethium atom
disjoint with: mercury atom
disjoint with: zinc atom
disjoint with: potassium atom
disjoint with: neptunium atom
disjoint with: chlorine atom
disjoint with: dubnium atom
disjoint with: radium atom
disjoint with: uranium atom
disjoint with: zirconium atom
disjoint with: rubidium atom
disjoint with: osmium atom
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom

polymeric shell
type: Class
equivalent class: Class
  intersection of: organic shell
  intersection of: Restriction
    on property: has component part
    some values from: polymer
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shell which is composed of a polymer.</ncicp:def-definition><ncicp:Definition_Review_Date>101010</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>polymeric shell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1870
preferred name: polymeric shell

metallic shell
type: Class
equivalent class: Class
  intersection of: shell
  intersection of: Restriction
    on property: has component part
    some values from: metal
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shell which is composed of a metal or a metal-based compound.</ncicp:def-definition><ncicp:Definition_Review_Date>101010</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>metallic shell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1871
preferred name: metallic shell

metal oxide shell
type: Class
equivalent class: Class
  intersection of: shell
  intersection of: Restriction
    on property: has component part
    some values from: metal oxide
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shell which is composed of metal oxide.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>metal oxide shell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1872
preferred name: metal oxide shell

silica shell
type: Class
equivalent class: Class
  intersection of: shell
  intersection of: Restriction
    on property: has component part
    some values from: silicon dioxide
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shel which is composed of silica.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>silica shell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1873
preferred name: silica shell

semiconductive shell
type: Class
equivalent class: Class
  intersection of: inorganic shell
  intersection of: Restriction
    on property: has property
    some values from: semiconductivity
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shell which exhibits semiconductivity.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>semiconductive shell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1874
synonym: semiconducting shell
preferred name: semiconductive shell

superparamagnetic core
type: Class
equivalent class: Class
  intersection of: inorganic core
  intersection of: Restriction
    on property: has property
    some values from: superparamagnetic
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An inorganic core which exhibits superparamagnetism.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>superparamagnetic core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1875
preferred name: superparamagnetic core

superparamagnetic iron oxide core
type: Class
equivalent class: Class
  intersection of: superparamagnetic core
  intersection of: Restriction
    on property: has component part
    some values from: iron oxide
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A superparamagnetic core which is composed of iron oxide.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>superparamagnetic iron oxide core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1876
preferred name: superparamagnetic iron oxide core

cationic surface
type: Class
subclass of: material boundary
subclass of: Restriction
  on property: has component part
  some values from: cation
subclass of: Restriction
  on property: has quality
  some values from: positive charge
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material boundary which is positively charged due to the presence of cations on the material boundary.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cationic surface</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1877
preferred name: cationic surface

anionic surface
type: Class
subclass of: material boundary
subclass of: Restriction
  on property: has quality
  some values from: negative charge
subclass of: Restriction
  on property: has component part
  some values from: anion
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material boundary which is negatively charged due to the presence of anions on the material boundary.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>anionic surface</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1878
preferred name: anionic surface

hydrophilic surface
type: Class
subclass of: material boundary
subclass of: Restriction
  on property: has property
  some values from: hydrophilic
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material boundary which exhibits affinity towards water molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>hydrophilic surface</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1879
preferred name: hydrophilic surface

drug directed against tumor DNA
type: Class
subclass of: anticancer drug directed against tumor cell
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug affecting the structure, function and synthesis of DNA in tumor cells</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>drug directed against tumor DNA</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_188
preferred name: drug directed against tumor DNA

hydrophobic surface
type: Class
subclass of: material boundary
subclass of: Restriction
  on property: has property
  some values from: hydrophobic
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material boundary which exhibits poor affinity to water molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>hydrophobic surface</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1880
preferred name: hydrophobic surface

surface-functionalized nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: surface functionalizing agent
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a molecule that is covalently attached to the surfce of the nanoparticle and that adds a functionality to the nanoparticle.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface-functionalized nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1881
preferred name: surface-functionalized nanoparticle

surface functionalizing role
type: Class
subclass of: functionalizing role
subclass of: Restriction
  on property: is realized in
  some values from: surface functionalization of nanoparticle
subclass of: Restriction
  on property: role of
  some values from: surface functionalizing agent
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A functionalizing role which inheres in a material entity that is covalently attached to the surface of a nanoparticle.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface functionalizing role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1882
synonym: nanoparticle surface functionalizing role
preferred name: surface functionalizing role

surface functionalization of nanoparticle
type: Class
subclass of: functionalization of nanoparticle
subclass of: Restriction
  on property: has agent
  some values from: surface functionalizing agent
subclass of: Restriction
  on property: realizes
  some values from: surface functionalizing role
subclass of: Restriction
  on property: has output participant
  some values from: surface-functionalized nanoparticle
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A functionalization of nanoparticle which is performed on the surface of the nanoparticle.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface functionalization of nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1883
synonym: functionalization of nanoparticle surface
preferred name: surface functionalization of nanoparticle

surface functionalizing agent
type: Class
equivalent class: Class
  intersection of: chemical component in nanoparticle formulation
  intersection of: Restriction
    on property: has role
    some values from: surface functionalizing role
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A chemical component in nanoparticle formulation which is used to functionalize the surface of a nanoparticle.</ncicp:def-definition><ncicp:Definition_Review_Date>101027</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface functionalizing agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1884
preferred name: surface functionalizing agent

surface modified nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: surface modifying agent
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A nanoparticle which has a surface that is chemically modified by the attachment of a small molecule or by the replacement of a surface functional group with a different type of functional group.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface modified nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1885
preferred name: surface modified nanoparticle

water-soluble nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has property
    some values from: soluble in water
subclass of: Restriction
  on property: has part
  some values from: hydrophilic surface
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A nanoparticle which dissolves in water.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>water-soluble nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1886
synonym: water soluble nanoparticle
preferred name: water-soluble nanoparticle

hydrophilic coat
type: Class
subclass of: coat
subclass of: Restriction
  on property: has property
  some values from: hydrophilic
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A coat which has affinity to water molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>hydrophilic coat</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1887
preferred name: hydrophilic coat
synonym: water-soluble coat

core component
type: Class
subclass of: molecular component in nanoparticle
subclass of: Restriction
  on property: part of
  some values from: core
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A molecular component in a nanoparticle, which forms part or whole of nanoparticle's core.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>core component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1888
preferred name: core component

shell component
type: Class
subclass of: molecular component in nanoparticle
subclass of: Restriction
  on property: part of
  some values from: shell
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A molecular component in a nanoparticle, which forms part or whole of the nanoparticle's shell.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>shell component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1889
preferred name: shell component

lanthanum atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: lanthanum
disjoint with: francium atom
disjoint with: caesium atom
disjoint with: nickel atom
disjoint with: fluorine atom
disjoint with: niobium atom
disjoint with: neon atom
disjoint with: promethium atom
disjoint with: mercury atom
disjoint with: zinc atom
disjoint with: potassium atom
disjoint with: neptunium atom
disjoint with: chlorine atom
disjoint with: dubnium atom
disjoint with: radium atom
disjoint with: uranium atom
disjoint with: zirconium atom
disjoint with: rubidium atom
disjoint with: osmium atom
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom

coat component
type: Class
subclass of: molecular component in nanoparticle
subclass of: Restriction
  on property: part of
  some values from: coat
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A molecular component in a nanoparticle, which forms part or whole of the coat on a nanoparticle.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>coat component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1890
preferred name: coat component

lipid monolayer
type: Class
subclass of: lipid membrane
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A lipid membrane which is one (lipid) molecule thick.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>lipid monolayer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1891
preferred name: lipid monolayer

silver nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: silver
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A nanoparticle which is basically composed of silver element.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>silver nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: Ag nanoparticle
code: NPO_1892
preferred name: silver nanoparticle

bimetallic nanoparticle
type: Class
subclass of: metal nanoparticle
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A metal nanoparticle which is composed of two types of metals.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>bimetallic nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1893
preferred name: bimetallic nanoparticle

surface group
type: Class
subclass of: functional group
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A functional group which is located on the surface of an object (.e.g., nanoparticle).</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1894
preferred name: surface group

particle
type: Class
subclass of: chemical entity
subclass of: Restriction
  on property: has quality
  some values from: hydrodynamic size
subclass of: Restriction
  on property: has quality
  some values from: particle concentration
subclass of: Restriction
  on property: has quality
  some values from: molecular weight
subclass of: Restriction
  on property: has quality
  some values from: mass
subclass of: Restriction
  on property: has quality
  some values from: Class
    union of: inorganic
    union of: organic
subclass of: Restriction
  on property: has quality
  some values from: size
subclass of: Restriction
  on property: has quality
  some values from: Class
    union of: electric charge
    union of: surface charge
subclass of: Restriction
  on property: has quality
  some values from: shape
subclass of: Restriction
  on property: has quality
  some values from: density
subclass of: Restriction
  on property: has quality
  some values from: particle size
subclass of: Restriction
  on property: has quality
  some values from: chemical composition
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A material entity which is a minute portion of matter.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>particle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1895
preferred name: particle

primary particle
type: Class
subclass of: particle
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A particle which is originally obtained from its source.</ncicp:def-definition><ncicp:Definition_Review_Date>101124</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PAS71 (draft 2.0) 2010-09-21</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>primary particle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1896
preferred name: primary particle

secondary particle
type: Class
subclass of: particle
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A particle which is composed of two or more primary particles held together by covalent bonds or by weak forces like Van der Waals forces or by simply physical entanglements.</ncicp:def-definition><ncicp:Definition_Review_Date>101124</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PAS 71 (draft 2.0) 2010-09-21</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>secondary particle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1897
preferred name: secondary particle

scale of measurement
type: Class
subclass of: generically_dependent_continuant
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A level of measureable information about a variable.</ncicp:def-definition><ncicp:Definition_Review_Date>101203</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>scale of measurement</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1898
synonym: measurement scale
preferred name: scale of measurement

interval scale of measurement
type: Class
subclass of: scale of measurement
definition: <ncicp:ComplexDefinition><ncicp:def-definition>An interval scale is a measurement scale in which a certain distance along the scale means the same thing no matter where on the scale you are, but where "0" on the scale does not represent the absence of the thing being measured.</ncicp:def-definition><ncicp:Definition_Review_Date>101203</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.statistics.com/resources/glossary/i/intscale.php (</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>interval scale of measurement</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1899
synonym: interval measurement scale
synonym: interval scale
preferred name: interval scale of measurement

g-block element
type: Class
subclass of: block element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electrons occupy g-orbitals.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>g-block element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_190
preferred name: g-block element

Celsius scale
type: Class
subclass of: interval scale of measurement
definition: <ncicp:ComplexDefinition><ncicp:def-definition>An interval scale of measurement which provides numerical values for temperature in the range, 0 to 100, where a value of zero corresponds to the melting point of water, while a value of 100 corresponds to the boiling point of water.</ncicp:def-definition><ncicp:Definition_Review_Date>101203</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Celsius scale</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Celsius scale
code: NPO_1900

Fahrenheit scale
type: Class
subclass of: interval scale of measurement
definition: <ncicp:ComplexDefinition><ncicp:def-definition>An interval scale of measurement, which provides numerical values for temperature in the range, 32 to 212, where a value of 32 corresponds to the melting point of water, while a value of 100 corresponds to the boiling point of water.</ncicp:def-definition><ncicp:Definition_Review_Date>101203</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Fahrenheit scale</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Fahrenheit scale
code: NPO_1901

Kelvin scale
type: Class
subclass of: ratio scale of measurement
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A ratio scale of measurement, which provides numerical values for temperature starting from the lowest attainable value equal to zero (absolute zero).</ncicp:def-definition><ncicp:Definition_Review_Date>101206</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Kelvin scale</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Kelvin scale
code: NPO_1902

ratio scale of measurement
type: Class
subclass of: scale of measurement
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A scale of measurement in which a certain distance along the scale means the same thing no matter where on the scale you are, and where "0" on the scale represents the absence of the thing being measured.</ncicp:def-definition><ncicp:Definition_Review_Date>101206</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.statistics.com/resources/glossary/r/ratioscale.php (Dec. 6, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ratio scale of measurement</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1903
synonym: ratio measurement scale
synonym: ratio scale
preferred name: ratio scale of measurement

nominal scale of measurement
type: Class
subclass of: scale of measurement
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A scale of measurement, which provides a list of categories to which objects can be classified. The data so classified are termed categorical data.</ncicp:def-definition><ncicp:Definition_Review_Date>101206</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.statistics.com/resources/glossary/n/nomscale.php (Dec. 6, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nominal scale of measurement</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1904
synonym: nominal measurement scale
synonym: nominal scale
preferred name: nominal scale of measurement

ordinal scale of measurement
type: Class
subclass of: scale of measurement
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A scale of measurement, which assigns values to objects based on their ranking with respect to one another.</ncicp:def-definition><ncicp:Definition_Review_Date>101206</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.statistics.com/resources/glossary/o/ordscale.php (Dec. 6, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ordinal scale of measurement</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1905
synonym: ordinal measurement scale
synonym: ordinal scale
preferred name: ordinal scale of measurement

logarithmic scale
type: Class
subclass of: interval scale of measurement
definition: <ncicp:ComplexDefinition><ncicp:def-definition>An interval scale of measurement, which provides log transformed values of a measured variable.</ncicp:def-definition><ncicp:Definition_Review_Date>101206</ncicp:Definition_Review_Date><ncicp:def-source>NCI</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>logarithmic scale</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1906
preferred name: logarithmic scale

pH scale
type: Class
subclass of: logarithmic scale
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A logarithmic scale which represents log (to the base 10) values of the concentration of hydrogen ions in aqueous solutions.</ncicp:def-definition><ncicp:Definition_Review_Date>101206</ncicp:Definition_Review_Date><ncicp:def-source>NCI</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>pH scale</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1907
preferred name: pH scale

nanoscale
type: Class
subclass of: interval scale of measurement
definition: <ncicp:ComplexDefinition><ncicp:def-definition>An interval scale of measurement which provides a range of values between 1 nm and a few hundred nm.</ncicp:def-definition><ncicp:Definition_Review_Date>110104</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanoscale</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1908
preferred name: nanoscale

engineered nanomaterial
type: Class
subclass of: nanomaterial
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A nanomaterial which is designed for a specific purpose or function.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>ISO/TS 80004-1</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>engineered nanomaterial</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1909
preferred name: engineered nanomaterial

biodegradable
type: Class
subclass of: disposition
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition which inheres in a material entity that can be decomposed by living organisms.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>biodegradable</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_191
preferred name: biodegradable
comment: e.g., biodegradable nanoparticle

nanostructured material
type: Class
subclass of: nanomaterial
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A nanomaterial which has an internal nanostructure or surface nanostructure.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>ISO/TS 80004-1</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanostructured material</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1910
preferred name: nanostructured material

MTT assay
type: Class
subclass of: cell viability assay
definition: <ncicp:ComplexDefinition><ncicp:def-definition>defintion</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>MTT assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: MTT assay
synonym: MTT cytoxicity assay
code: NPO_1911

size assay
type: Class
subclass of: physical assay
subclass of: Restriction
  on property: uses technique
  some values from: Class
    union of: electron microscopy
    union of: atomic force microscopy
    union of: dynamic light scattering
subclass of: Restriction
  on property: has endpoint of measurement
  some values from: Class
    union of: particle size
    union of: hydrodynamic size
    union of: polydispersity
    union of: size
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A physical assay which is used to measure the size of a particle or molecule.</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>size assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1912
preferred name: size assay

dendrimer generation
type: Class
subclass of: independent specific individual quality
subclass of: Restriction
  on property: quality of
  some values from: dendrimer
definition: <ncicp:ComplexDefinition><ncicp:def-definition>The generation number of a dendrimer.</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dendrimer generation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1913
preferred name: dendrimer generation
synonym: generation number

hydrodynamic size
type: Class
subclass of: dependent general individual quality
subclass of: Restriction
  on property: has unit of measure
  some values from: Class
    union of: length unit
    union of: area unit
    union of: volume unit
definition: <ncicp:ComplexDefinition><ncicp:def-definition>The size of a particle or molecule in an aqueous solution.</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydrodynamic size</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1914
preferred name: hydrodynamic size

hydrodynamic diameter
type: Class
subclass of: hydrodynamic size
subclass of: Restriction
  on property: has unit of measure
  some values from: length unit
definition: <ncicp:ComplexDefinition><ncicp:def-definition>The hydrodynamic size which is the diameter of a particle or molecule (approximated as a sphere) in an aqueous solution.</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydrodynamic diameter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1915
preferred name: hydrodynamic diameter

z-average
type: Class
subclass of: measure of central tendency
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition to be added</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>z-average</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1916
preferred name: z-average

diaminobutane
type: Class
subclass of: organic compound or molecule
subclass of: Restriction
  on property: has part
  some values from: primary amine group
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition to be added</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>diaminobutane</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1917
preferred name: diaminobutane

tris(hydroxymethyl)aminomethane
type: Class
subclass of: organic compound or molecule
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition to be added.</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tris(hydroxymethyl)aminomethane</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1918
preferred name: tris(hydroxymethyl)aminomethane

poly(amidoamine)
type: Class
subclass of: polymer
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition to be added.</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>poly(amidoamine)</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1919
preferred name: poly(amidoamine)

protein role
type: Class
subclass of: molecular role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular role inhering in a protein molecule by virtue of the protein's function.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>protein role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_192
preferred name: protein role

magnevist
type: Class
subclass of: organic compound or molecule
subclass of: Restriction
  on property: has application
  some values from: MRI contrast agent
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition to be entered.</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>magnevist</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1920
preferred name: magnevist

material synthesis technique
type: Class
subclass of: technique
subclass of: Restriction
  on property: technique used for
  some values from: sample preparation
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A technique which describes the way how a material is synthesized.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>material synthesis technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1921
preferred name: material synthesis technique
synonym: method of synthesis
synonym: synthesis method
synonym: synthesis technique

solution-based chemistry technique
type: Class
subclass of: material synthesis technique
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A material synthesis technique in which chemical reactions require the use of a solution.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>solution-based chemistry technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1922
synonym: solution based chemistry method
synonym: solution-based chemistry
preferred name: solution-based chemistry technique

hydrothermal method
type: Class
subclass of: solution-based chemistry technique
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A solution-based chemistry technique in which substances are crystallized from high temperature aqueous solutions at high vapor pressures.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://en.wikipedia.org/wiki/Hydrothermal_synthesis</ncicp:attr><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydrothermal method</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1923
preferred name: hydrothermal method
synonym: hydrothermal technique

micro-emulsion method
type: Class
subclass of: solution-based chemistry technique
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A solution-based chemistry technique for dispersing two or more immiscible liquids as micron-sized droplets by shaking, stirring or homogenising the mixture.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.rsc.org/publishing/journals/prospect/ontology.asp?id=CMO:0.0002150$MSID=b916837k</ncicp:attr><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>micro-emulsion method</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1924
preferred name: micro-emulsion method
synonym: micro-emulsion technique

sol-gel chemical process
type: Class
subclass of: solution-based chemistry technique
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A solution-based chemical technique which ...[To be completed]</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>sol-gel chemical process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1925
preferred name: sol-gel chemical process

solvent displacement method
type: Class
subclass of: solution-based chemistry technique
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition [to do]</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>solvent displacement method</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1926
preferred name: solvent displacement method

sonochemical method
type: Class
subclass of: solution-based chemistry technique
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition [to do]</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>sonochemical method</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1927
preferred name: sonochemical method

template-assisted solution-based synthesis
type: Class
subclass of: solution-based chemistry technique
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition [to do]</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>template-assisted solution-based synthesis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1928
preferred name: template-assisted solution-based synthesis

thin film deposition technique
type: Class
subclass of: material synthesis technique
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A synthesis technique which involves the layer-by-layer deposition of individual atoms from a material source (solid, liquid, vapor or gas), onto the surface of a material (substrate).</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thin film deposition technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1929
preferred name: thin film deposition technique

zinc sulfide quantum dot
type: Class
subclass of: quantum dot
subclass of: Restriction
  on property: has component part
  some values from: zinc sulfide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quantum dot composed of zinc sulfide.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>zinc sulfide quantum dot</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_193
synonym: ZnS quantum dot
preferred name: zinc sulfide quantum dot

chemical vapor deposition
type: Class
subclass of: thin film deposition technique
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A thin film deposition technique in which one or more volatile precursors react and/or decompose on the surface of the substrate.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>chemical vapor deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: CVD
synonym: CVD technique
code: NPO_1930
preferred name: chemical vapor deposition
synonym: chemical vapor deposition technique

atomic layer deposition
type: Class
subclass of: chemical vapor deposition
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A chemical vapor deposition technique in which gaseous precursors chemically react with a surface in a sequential manner.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>atomic layer deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1931
preferred name: atomic layer deposition
synonym: atomic layer deposition technique

metal-organic chemical vapor deposition
type: Class
subclass of: chemical vapor deposition
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A chemical vapor deposition technique in which metal organic compounds in gas phase (at moderate pressures) react to form epitaxial layers of material on the surface of the substrate.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>metal-organic chemical vapor deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: MOCVD
synonym: MOVPE
code: NPO_1932
synonym: OMVPE
preferred name: metal-organic chemical vapor deposition
synonym: metalorganic vapor phase epitaxy
synonym: organometallic vapor phase epitaxy

plasma-enhanced chemical vapor deposition
type: Class
subclass of: chemical vapor deposition
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A chemical vapor deposition technique in which gaseous precursors react when a plasma of the gases is created by RF (radio frequency) or DC discharge between two electrodes.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>plasma-enhanced chemical vapor deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1933
synonym: PECVD
preferred name: plasma-enhanced chemical vapor deposition

thermal chemical vapor deposition
type: Class
subclass of: chemical vapor deposition
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A chemical vapor deposition in which the substrate is heated.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thermal chemical vapor deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1934
synonym: TCVD
synonym: rapid thermal CVD
synonym: rapid thermal chemical vapor deposition
synonym: thermal CVD
preferred name: thermal chemical vapor deposition

physical vapor deposition
type: Class
subclass of: thin film deposition technique
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A thin film deposition technique in which atoms from the surface of a solid material are vaporized by physical methods (e.g. by bombarding the solid surface with an energetic ion beam, laser beam, or electron beam), and then transported for deposition on the surface of the substrate. The deposition process takes place in under low pressure or vacuum conditions.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>physical vapor deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1935
synonym: PVD
preferred name: physical vapor deposition
synonym: physical vapor deposition technique

pulsed laser deposition
type: Class
subclass of: physical vapor deposition
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A physical vapor deposition technique in whcih the source material is vaporized by irradiating the target surface of the source material by a pulsed laser beam.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>pulsed laser deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1936
preferred name: pulsed laser deposition
synonym: pulsed laser deposition technique

sputter deposition
type: Class
subclass of: physical vapor deposition
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A physical vapor deposition technique in which atoms from the surface of a solid material are vaporized by bombarding the surface with energetic particles (e.g., accelerated ions).</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>sputter deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1937
preferred name: sputter deposition
synonym: sputter deposition technique

magnetron sputtering
type: Class
subclass of: sputter deposition
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A type of sputter deposition where a magnetron is used to direct the flow of high energy electrons for the sputtering process. A magnetron is a vacuum tube in which the electrons generated from a heated cathode flows under the control of an applied magnetic field.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>magnetron sputtering</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1938
preferred name: magnetron sputtering

thermal evaporation
type: Class
subclass of: physical vapor deposition
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A physical vapor deposition technique in which the source material is evaporated in vacuum, and the vaporized material condenses on the surface of the substrate.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thermal evaporation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1939
preferred name: thermal evaporation
synonym: thermal evaporation method
synonym: thermal evaporation technique

electron beam physical vapor deposition
type: Class
subclass of: thermal evaporation
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A physical vapor deposition in which a target anode is bombarded with an electron beam given off by a charged tungsten filament under high vacuum.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://en.wikipedia.org/wiki/Electron_beam_physical_vapor_deposition</ncicp:attr><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>electron beam physical vapor deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: EBPVD
code: NPO_1940
preferred name: electron beam physical vapor deposition

molecular beam epitaxy
type: Class
subclass of: thermal evaporation
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A thermal evaporation technique in which the evaporated atoms in high or ultra-high vacuum do not interact with each other until they reach the surface of the substrate. The deposition occurs at a slow rate to allow controlled growth of a monocrystalline film on a monocrystalline substrate.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>molecular beam epitaxy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1941
preferred name: molecular beam epitaxy

resistive heating
type: Class
subclass of: thermal evaporation
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A thermal evaporation technique in which heat is generated using electric conductors carrying current.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>resistive heating</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1942
preferred name: resistive heating

RF-induction technique
type: Class
subclass of: thermal evaporation
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A thermal evaporation technique in which the target surface of the source material is heated by an electromagnetic field induced by a RF (radio frequency) signal.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>RF-induction technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1943
preferred name: RF-induction technique

synthesis part
type: Class
subclass of: process
subclass of: Restriction
  on property: part of
  some values from: Class
    union of: sample preparation
    union of: material synthesis technique
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A process which is conducted or occurs during the synthesis of a material.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>synthesis part</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1944
preferred name: synthesis part

macroscopic synthesis part
type: Class
subclass of: synthesis part
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A process which is conducted during synthesis.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>macroscopic synthesis part</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1945
preferred name: macroscopic synthesis part

precipitation
type: Class
subclass of: macroscopic synthesis part
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>precipitation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1946
preferred name: precipitation

co-precipitation
type: Class
subclass of: precipitation
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A solution-based chemistry technique which enables the precipitation of soluble substances.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>co-precipitation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1947
preferred name: co-precipitation

purification
type: Class
subclass of: macroscopic synthesis part
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>purification</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1948
preferred name: purification

quenching
type: Class
subclass of: macroscopic synthesis part
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>quenching</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1949
preferred name: quenching

linkage
type: Class
subclass of: fiat material part
subclass of: Restriction
  on property: bearer of
  some values from: chemical interaction
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fiat material part formed by chemically linking or associating two or more material entities (molecular entities, groups, nanomaterials) or parts thereof by molecular forces.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_195
synonym: association
synonym: chemical association
preferred name: linkage

rinsing
type: Class
subclass of: macroscopic synthesis part
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>rinsing</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1950
preferred name: rinsing

shaking
type: Class
subclass of: macroscopic synthesis part
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>shaking</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1951
preferred name: shaking

vortex shaking
type: Class
subclass of: shaking
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>vortex shaking</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1952
preferred name: vortex shaking

centrifugation
type: Class
subclass of: macroscopic synthesis part
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>centrifugation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1953
preferred name: centrifugation

cooling
type: Class
subclass of: macroscopic synthesis part
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cooling</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1954
preferred name: cooling

dissolution
type: Class
subclass of: macroscopic synthesis part
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dissolution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1955
preferred name: dissolution

drying
type: Class
subclass of: macroscopic synthesis part
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>drying</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1956
preferred name: drying

freeze-drying
type: Class
subclass of: drying
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>freeze-drying</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1957
preferred name: freeze-drying

heating
type: Class
subclass of: macroscopic synthesis part
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>heating</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1958
preferred name: heating

homogenization
type: Class
subclass of: macroscopic synthesis part
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>homogenization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1959
preferred name: homogenization

Group 5 Element
type: Class
equivalent class: Class
  union of: dubnium
  union of: tantalum
  union of: vanadium
  union of: niobium
subclass of: group element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 5 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Group 5 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Group 5 Element
code: NPO_196
synonym: vanadium group element

mixing
type: Class
subclass of: macroscopic synthesis part
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>mixing</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1960
preferred name: mixing

sonication
type: Class
subclass of: macroscopic synthesis part
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>sonication</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1961
preferred name: sonication

surface coating
type: Class
subclass of: microscopic synthesis part
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>surface coating</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1962
preferred name: surface coating

washing
type: Class
subclass of: macroscopic synthesis part
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>washing</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1963
preferred name: washing

microscopic synthesis part
type: Class
subclass of: synthesis part
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A process which takes place during synthesis of a sample at the microscopic level.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>microscopic synthesis part</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1964
preferred name: microscopic synthesis part

PEGylation
type: Class
subclass of: surface coating
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>PEGylation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1965
preferred name: PEGylation

agglomeration
type: Class
subclass of: microscopic synthesis part
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>agglomeration</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1966
preferred name: agglomeration

aggregation
type: Class
subclass of: microscopic synthesis part
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>aggregation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1967
preferred name: aggregation

crosslinking
type: Class
subclass of: microscopic synthesis part
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>crosslinking</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1968
preferred name: crosslinking

dispersion
type: Class
subclass of: microscopic synthesis part
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dispersion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1969
preferred name: dispersion

gold nanocage
type: Class
subclass of: nanocage
subclass of: Restriction
  on property: has part
  some values from: gold
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanocage composed of gold element.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gold nanocage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: Gold nanocages, some 40 nanometers in diameter can be made by replacing the silver atoms of silver nanotubes.
code: NPO_197
preferred name: gold nanocage

self-assembly
type: Class
subclass of: microscopic synthesis part
definition: <ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>self-assembly</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1970
preferred name: self-assembly

biological material entity
type: Class
subclass of: material entity
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A material entity which occurs exclusively in microorganisms, plants, animals, and human beings.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>biological material entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1971
preferred name: biological material entity

chemical entity
type: Class
subclass of: material entity
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A material entity which chemical interaction</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>chemical entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1972
preferred name: chemical entity

chemical substance
type: Class
subclass of: chemical entity
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A chemical entity which can be identified based on its physical state, chemical composition or molecular structure.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>chemical substance</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1973
preferred name: chemical substance

pure substance
type: Class
subclass of: chemical substance
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A chemical substance which as a constant, defined composition and cannot be separated into simpler substances by physical methods.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.teacherbridge.org/public/bhs/teachers/Dana/Matter.html</ncicp:attr><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>pure substance</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1974
preferred name: pure substance

biological fluid
type: Class
subclass of: biological material entity
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A biological material entity which is fluid-like.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>biological fluid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1975
preferred name: biological fluid

biological molecule
type: Class
equivalent class: Class
  union of: lipid
  union of: carbohydrate
  union of: protein
subclass of: biological material entity
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A biological material entity which is a small molecule or a macromolecule.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>biological molecule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1976
preferred name: biological molecule

compound by application
type: Class
subclass of: compound or molecule
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which is identified based on its application.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>compound by application</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1977
preferred name: compound by application

compound by chemical composition
type: Class
subclass of: compound or molecule
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which is identified based on its chemical composition.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>compound by chemical composition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1978
preferred name: compound by chemical composition

compound for imaging
type: Class
subclass of: compound by application
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which has specific properties that makes it useful for imaging applications.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>compound for imaging</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1979
preferred name: compound for imaging

beryllium
type: Class
subclass of: element
disjoint with: mercury
disjoint with: boron
disjoint with: dysprosium
disjoint with: radon
disjoint with: magnesium
disjoint with: calcium
disjoint with: protactinium
disjoint with: fluorine
disjoint with: neodymium
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium

compound for material synthesis
type: Class
subclass of: compound by application
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which plays a role in material synthesis.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>compound for material synthesis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1980
preferred name: compound for material synthesis

compound for targeting
type: Class
subclass of: compound by application
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which is used for targeting other molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>compound for targeting</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1981
preferred name: compound for targeting

compound for therapy
type: Class
subclass of: compound by application
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which is used for therapeutic applications.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>compound for therapy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1982
preferred name: compound for therapy

journal article
type: Class
subclass of: generically_dependent_continuant
subclass of: Restriction
  on property: has journal name
  some values from: string
subclass of: Restriction
  on property: has PubMedID
  some values from: string
subclass of: Restriction
  on property: has publication year
  some values from: integer
subclass of: Restriction
  on property: has author
  some values from: string
subclass of: Restriction
  on property: has abstract
  some values from: string
subclass of: Restriction
  on property: has DOI
  some values from: string
definition: <ncicp:ComplexDefinition><ncicp:def-definition>To be defined</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>journal article</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1983
preferred name: journal article

datatype
type: Class
subclass of: generically_dependent_continuant
definition: <ncicp:ComplexDefinition><ncicp:def-definition>To be defined</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>datatype</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1984
preferred name: datatype

string
type: Class
subclass of: datatype
definition: <ncicp:ComplexDefinition><ncicp:def-definition>string datatype</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>string</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1985
preferred name: string

integer
type: Class
subclass of: datatype
definition: <ncicp:ComplexDefinition><ncicp:def-definition>integer datatype</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>integer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1986
preferred name: integer

floating point
type: Class
subclass of: datatype
definition: <ncicp:ComplexDefinition><ncicp:def-definition>floating point datatype</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>floating point</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1987
preferred name: floating point

blood coagulation pathway
type: Class
subclass of: developmental process
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A collection of processes that leads the way for blood coagulation to take place.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>blood coagulation pathway</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1989
preferred name: blood coagulation pathway

nanomaterial
type: Class
equivalent class: Class
  intersection of: chemical substance
  intersection of: Class
    union of: nano-object
    union of: engineered nanomaterial
    union of: nanostructured material
    union of: nanoparticle
    union of: nanoparticle formulation
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A chemical substance which has atleast one external dimension or internal structure or surface structure in the nanoscale size range.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>ISO/TS 80004-1</ncicp:attr><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanomaterial</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_199
editor note: [Previous definition]: A material entity which is synthesized, characterized, and which has at least one spatial size dimension distinguishable in the nanoscale (1-100 nm) range.
preferred name: nanomaterial

intrinsic pathway of blood coagulation
type: Class
subclass of: blood coagulation pathway
definition: <ncicp:ComplexDefinition><ncicp:def-definition>To be defined.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>intrinsic pathway of blood coagulation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1990
preferred name: intrinsic pathway of blood coagulation

extrinsic pathway of blood coagulation
type: Class
subclass of: blood coagulation pathway
definition: <ncicp:ComplexDefinition><ncicp:def-definition>To be defined.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>extrinsic pathway of blood coagulation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1991
preferred name: extrinsic pathway of blood coagulation

final common pathway of blood coagulation
type: Class
subclass of: blood coagulation pathway
definition: <ncicp:ComplexDefinition><ncicp:def-definition>To be defined.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>final common pathway of blood coagulation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1992
preferred name: final common pathway of blood coagulation

blood coagulation time
type: Class
subclass of: duration
subclass of: Restriction
  on property: inidicator of
  some values from: blood coagulation pathway
definition: <ncicp:ComplexDefinition><ncicp:def-definition>Time needed for blood coagulation to occur.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>blood coagulation time</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1993
preferred name: blood coagulation time

activated partial thromboplastin time
type: Class
subclass of: blood coagulation time
subclass of: Restriction
  on property: inidicator of
  some values from: extrinsic pathway of blood coagulation
definition: <ncicp:ComplexDefinition><ncicp:def-definition>To be defined.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>activated partial thromboplastin time</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: APTT
code: NPO_1994
preferred name: activated partial thromboplastin time

prothrombin time
type: Class
subclass of: blood coagulation time
subclass of: Restriction
  on property: inidicator of
  some values from: intrinsic pathway of blood coagulation
definition: <ncicp:ComplexDefinition><ncicp:def-definition>To be defined.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>prothrombin time</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1995
synonym: PT
preferred name: prothrombin time

thrombin time
type: Class
subclass of: blood coagulation time
subclass of: Restriction
  on property: inidicator of
  some values from: final common pathway of blood coagulation
definition: <ncicp:ComplexDefinition><ncicp:def-definition>To be defined.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thrombin time</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1996
synonym: TT
preferred name: thrombin time

coagulometer
type: Class
subclass of: instrument
definition: <ncicp:ComplexDefinition><ncicp:def-definition>an instrument which is used to measure the time required for a sample of fluid (blood) to coagulate.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>coagulometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1997
preferred name: coagulometer

biological specimen
type: Class
subclass of: biological material entity
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A biological material entity that is analyzed in a bioassay.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>biological specimen</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1998
preferred name: biological specimen
synonym: biospecimen

centrifuge
type: Class
subclass of: instrument
definition: <ncicp:ComplexDefinition><ncicp:def-definition>An instrument which is a machine that uses centrifugal force to separate substances of different densities or to remove moisture.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.merriam-webster.com (last accessed: November 6, 2011)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>centrifuge</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1999
preferred name: centrifuge

pH-sensitive
type: Class
subclass of: sensitivity to stimulus
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition, inhering in any material entity, whose structure or function can be altered by changes in pH of the medium containing it.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>pH-sensitive</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_200
preferred name: pH-sensitive
comment: sensitive to pH Change

incubation
type: Class
subclass of: technique
subclass of: Restriction
  on property: has time period
  some values from: duration
subclass of: Restriction
  on property: has temperature condition
  some values from: temperature value
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A technique used for incubating mixtures in an assay.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>incubation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_2000
preferred name: incubation

DNA topoisomerase type I activity
type: Class
subclass of: DNA topoisomerase activity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>DNA topoisomerase type I activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: DNA topoisomerase type I activity
code: NPO_203

francium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: francium
disjoint with: caesium atom
disjoint with: nickel atom
disjoint with: fluorine atom
disjoint with: niobium atom
disjoint with: neon atom
disjoint with: promethium atom
disjoint with: mercury atom
disjoint with: zinc atom
disjoint with: potassium atom
disjoint with: neptunium atom
disjoint with: chlorine atom
disjoint with: dubnium atom
disjoint with: radium atom
disjoint with: uranium atom
disjoint with: zirconium atom
disjoint with: rubidium atom
disjoint with: osmium atom
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom

component role in nanoparticle
type: Class
subclass of: molecular role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular role which inheres specifically in a a chemical component of a nanoparticle formulation with respect to its use in the formulation of nanoparticles.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>component role in nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_206
preferred name: component role in nanoparticle

hydrophobic core of lipid bilayer
type: Class
subclass of: core site
subclass of: Restriction
  on property: part of
  some values from: lipid bilayer
disjoint with: hydrophilic space between lipid bilayers
disjoint with: dendrimer core
disjoint with: hollow core of nanocapsule
disjoint with: nuclear core of nanocell
disjoint with: hollow core of nanoshell
disjoint with: hollow core of nanocage
disjoint with: hydrophobic core of micelle
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The hydrophobic space within the lipid bilayer.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydrophobic core of lipid bilayer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_207
preferred name: hydrophobic core of lipid bilayer

fluorobenzene group
type: Class
subclass of: aryl halide group
subclass of: Restriction
  on property: has part
  some values from: fluoro group
subclass of: Restriction
  on property: part of
  some values from: fluorobenzene derivative
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aryl halide group containing an aromatic benzene ring attached to one or more fluorine atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fluorobenzene group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_208
preferred name: fluorobenzene group

caesium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: caesium
disjoint with: nickel atom
disjoint with: fluorine atom
disjoint with: niobium atom
disjoint with: neon atom
disjoint with: promethium atom
disjoint with: mercury atom
disjoint with: zinc atom
disjoint with: potassium atom
disjoint with: neptunium atom
disjoint with: chlorine atom
disjoint with: dubnium atom
disjoint with: radium atom
disjoint with: uranium atom
disjoint with: zirconium atom
disjoint with: rubidium atom
disjoint with: osmium atom
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom

metal
type: Class
equivalent class: Class
  union of: alkali earth metal
  union of: inner transition element
  union of: alkali metal
  union of: other metal
  union of: transition element
subclass of: series element
disjoint with: non-metal
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A series element which is an alkali earth metal or alkali metal or inner transition element or transition element or other metal.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>metal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_210
preferred name: metal

attachment
type: Class
subclass of: linkage
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A linkage in which two molecular entities or parts thereof are joined to form a chemically conjugated molecular entity.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>attachment</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_211
preferred name: attachment
synonym: chemical conjugation

sulfonamide linkage
type: Class
subclass of: covalent linkage
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a sulfonamide group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>sulfonamide linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_212
preferred name: sulfonamide linkage

nickel atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: nickel
disjoint with: fluorine atom
disjoint with: niobium atom
disjoint with: neon atom
disjoint with: promethium atom
disjoint with: mercury atom
disjoint with: zinc atom
disjoint with: potassium atom
disjoint with: neptunium atom
disjoint with: chlorine atom
disjoint with: dubnium atom
disjoint with: radium atom
disjoint with: uranium atom
disjoint with: zirconium atom
disjoint with: rubidium atom
disjoint with: osmium atom
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom

material boundary
type: Class
subclass of: independent_continuant
subclass of: Restriction
  on property: has quality
  some values from: surface composition
subclass of: Restriction
  on property: has quality
  some values from: surface charge
subclass of: Restriction
  on property: has property
  some values from: surface property
subclass of: Restriction
  on property: part of
  some values from: material entity
subclass of: Restriction
  on property: has quality
  some values from: surface area
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An independent continuant which describes a 2-dimensional, inner/outer surface of a material entity. The material boundary separates a material entity in its identity from other surrounding material entities.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>material boundary</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_214
preferred name: material boundary
synonym: material surface
synonym: surface

mercury
type: Class
subclass of: element
disjoint with: boron
disjoint with: dysprosium
disjoint with: radon
disjoint with: magnesium
disjoint with: calcium
disjoint with: protactinium
disjoint with: fluorine
disjoint with: neodymium
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon

polymer-coated nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: Class
      intersection of: polymer
      intersection of: Restriction
        on property: has role
        some values from: nanoparticle surface modifying role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a coating agent composed of polymer.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>polymer-coated nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_218
preferred name: polymer-coated nanoparticle

stimulus of electric field
type: Class
subclass of: external stimulus for nanoparticle function
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by electric field.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>stimulus of electric field</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_219
preferred name: stimulus of electric field

other non-metal
type: Class
equivalent class: Class
  union of: nitrogen
  union of: phosphorus
  union of: oxygen
  union of: sulfur
  union of: carbon
  union of: selenium
subclass of: non-metal
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A non-metal which is any of the following elements: carbon, nitrogen, oxygen, phosphorus, selenium, sulfur.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>other non-metal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_220
preferred name: other non-metal

thiocyanate group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: thiocyanate compound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure N#C-S-. The group is characteristic of a thiocyanate organic molecule wherein it is attached to an organic group via a single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thiocyanate group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_221
preferred name: thiocyanate group

fluorine atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 9
disjoint with: niobium atom
disjoint with: neon atom
disjoint with: promethium atom
disjoint with: mercury atom
disjoint with: zinc atom
disjoint with: potassium atom
disjoint with: neptunium atom
disjoint with: chlorine atom
disjoint with: dubnium atom
disjoint with: radium atom
disjoint with: uranium atom
disjoint with: zirconium atom
disjoint with: rubidium atom
disjoint with: osmium atom
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom

hydrogen bonding
type: Class
subclass of: permanent dipole-dipole interaction
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A permanent dipole-dipole interaction between a hydrogen atom of -OH or -NH part of a molecule and a small, highly electronegative atom of the other polar molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydrogen bonding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_223
preferred name: hydrogen bonding

dendrimer generation layer
type: Class
subclass of: fiat material part
subclass of: Restriction
  on property: part of
  some values from: dendrimer
subclass of: Restriction
  on property: has part
  some values from: dendrimer cavity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular structure which describes an interior layer, formed around the dendrimer core by the addition of dendrimer branches.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dendrimer generation layer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_224
preferred name: dendrimer generation layer

niobium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: niobium
disjoint with: neon atom
disjoint with: promethium atom
disjoint with: mercury atom
disjoint with: zinc atom
disjoint with: potassium atom
disjoint with: neptunium atom
disjoint with: chlorine atom
disjoint with: dubnium atom
disjoint with: radium atom
disjoint with: uranium atom
disjoint with: zirconium atom
disjoint with: rubidium atom
disjoint with: osmium atom
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom

two-dimensional nano-object
type: Class
subclass of: nano-object
synonym: 2-D nano-object
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A nano-object which has two external dimensions in the nanoscale (between 1 and 1000 nm) range.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>two-dimensional nano-object</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_226
preferred name: two-dimensional nano-object

targeting ligand
type: Class
subclass of: targeting agent
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A targeting agent, which is a ligand or small molecule that binds to larger molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>targeting ligand</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_227
preferred name: targeting ligand

cadmium selenide
type: Class
subclass of: inorganic compound or molecule
subclass of: Restriction
  on property: has part
  some values from: selenium
subclass of: Restriction
  on property: has part
  some values from: cadmium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An inorganic compound or molecule which is composed of cadmium and selenium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cadmium selenide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: CdSe
code: NPO_228
preferred name: cadmium selenide

amide group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: amide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -E(=O)-NH2 or -E(=O)-NH- or -E(=O)-N(-)-, where E could denote one of the following atoms: carbon (C), sulfur (S) or phosphorus (P). The group is characteristic of an amide compound wherein it is attached to organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>amide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_229
preferred name: amide group

isothiourea linkage
type: Class
subclass of: covalent linkage
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an isothiourea group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>isothiourea linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_231
preferred name: isothiourea linkage

boron
type: Class
subclass of: element
disjoint with: dysprosium
disjoint with: radon
disjoint with: magnesium
disjoint with: calcium
disjoint with: protactinium
disjoint with: fluorine
disjoint with: neodymium
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum

succinimidyl carbonate group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: succinimidyl carbonate compound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group, the structure of which consists of a saturated cyclic ring made up of four carbon atoms and one nitrogen atom; and each of the two carbon atoms, adjacent to the nitrogen atom, are bonded to an oxygen atom via a double bond, while the nitrogen atom is bonded to one oxygen atom of the carbonate group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>succinimidyl carbonate group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_234
preferred name: succinimidyl carbonate group

DNA alkylating agent
type: Class
equivalent class: Class
  intersection of: DNA binding agent
  intersection of: Restriction
    on property: has function
    some values from: Class
      intersection of: alkylating function
      intersection of: Restriction
        on property: is realized in
        some values from: DNA alkylation
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>DNA crosslinking agent, which alkylates DNA.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>DNA alkylating agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: DNA alkylating agent
code: NPO_235
synonym: antineoplastic alkylating agent

carbamate ester linkage between primary amine and carbonate ester
type: Class
subclass of: carbamate ester linkage
subclass of: Restriction
  on property: derives from
  some values from: primary amine group
subclass of: Restriction
  on property: part of
  some values from: carbamate ester group
subclass of: Restriction
  on property: derives from
  some values from: carbonate ester group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carbamate ester linkage which is formed between a primary amine and a carbonate ester, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carbamate ester linkage between primary amine and carbonate ester</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_236
preferred name: carbamate ester linkage between primary amine and carbonate ester

amidine linkage
type: Class
subclass of: covalent linkage
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an amidine group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>amidine linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_238
preferred name: amidine linkage

nanobomb
type: Class
subclass of: nanodevice
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as an explosive device.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanobomb</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: An explosive device comprised of carbon nanotubes. These nanoscale devices have desirable optical and thermal properties that can be exploited for novel cancer therapeutics. The ability to manipulate these properties facilitates a controlled, localized activation and clearance mechanism of diseased or abnormal cells.
DB xref ID: NCIT: C62367
code: NPO_239
preferred name: nanobomb

isourea linkage
type: Class
subclass of: covalent linkage
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an isourea group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>isourea linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_240
preferred name: isourea linkage

oblate spheroidal shape
type: Class
subclass of: spheroidal shape
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spheroidal shape, which is generated by half-revolution of an ellipse around its minor axis.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>oblate spheroidal shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_241
preferred name: oblate spheroidal shape

ionizable aminoacid
type: Class
equivalent class: Class
  intersection of: aminoacid
  intersection of: Restriction
    on property: has part
    some values from: Class
      intersection of: alpha-aminoacid sidechain
      intersection of: Restriction
        on property: has property
        some values from: ionizable
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aminoacid which can become ionized.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ionizable aminoacid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_242
preferred name: ionizable aminoacid

dysprosium
type: Class
subclass of: element
disjoint with: radon
disjoint with: magnesium
disjoint with: calcium
disjoint with: protactinium
disjoint with: fluorine
disjoint with: neodymium
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium

radon
type: Class
subclass of: element
disjoint with: magnesium
disjoint with: calcium
disjoint with: protactinium
disjoint with: fluorine
disjoint with: neodymium
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium

outer hydrophilic surface of liposome
type: Class
subclass of: hydrophilic surface
subclass of: Restriction
  on property: part of
  some values from: liposome
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Outer surface of a liposome vesicle, formed by the polar head groups of lipid molecules that compose the lipid bilayer.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>outer hydrophilic surface of liposome</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_245
preferred name: outer hydrophilic surface of liposome

neon atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: neon
disjoint with: promethium atom
disjoint with: mercury atom
disjoint with: zinc atom
disjoint with: potassium atom
disjoint with: neptunium atom
disjoint with: chlorine atom
disjoint with: dubnium atom
disjoint with: radium atom
disjoint with: uranium atom
disjoint with: zirconium atom
disjoint with: rubidium atom
disjoint with: osmium atom
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom

imide linkage
type: Class
subclass of: covalent linkage
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an imide group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>imide linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_247
preferred name: imide linkage

promethium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 61
disjoint with: mercury atom
disjoint with: zinc atom
disjoint with: potassium atom
disjoint with: neptunium atom
disjoint with: chlorine atom
disjoint with: dubnium atom
disjoint with: radium atom
disjoint with: uranium atom
disjoint with: zirconium atom
disjoint with: rubidium atom
disjoint with: osmium atom
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom

magnesium
type: Class
subclass of: element
disjoint with: calcium
disjoint with: protactinium
disjoint with: fluorine
disjoint with: neodymium
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium

calcium
type: Class
subclass of: element
disjoint with: protactinium
disjoint with: fluorine
disjoint with: neodymium
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium

lipid
type: Class
subclass of: organic compound or molecule
subclass of: Restriction
  on property: has property
  some values from: amphiphilic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound of biological origin, which contains hydrocarbons and it is insoluble in water but soluble in non-polar solvents.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>lipid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_252
comment: [ChEBI definition]: A loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids.
comment: [NCI_Thesaurus definition]: A class of hydrocarbon-containing organic compounds. Lipids are insoluble in water but soluble in nonpolar solvents and play important roles in living organisms: these roles include functioning as energy storage molecules, serving as structural components of cell membranes, and constituting important signaling molecules. Lipids can be subdivided into 2 groups: fatty acids and glycerides.
preferred name: lipid

protactinium
type: Class
subclass of: element
disjoint with: fluorine
disjoint with: neodymium
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium

non-metal
type: Class
subclass of: series element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A series element which is not a metal.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>non-metal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_255
preferred name: non-metal

topoisomerase inhibitor
type: Class
equivalent class: Class
  intersection of: enzyme inhibitor drug
  intersection of: Restriction
    on property: has role
    some values from: Class
      intersection of: inhibitor role
      intersection of: Restriction
        on property: is realized in
        some values from: inhibition of DNA topoisomerase activity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Enzyme inhibitor that inhibits the enzymatic activity of topoisomerases.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>topoisomerase inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C1748
code: NPO_256
preferred name: topoisomerase inhibitor

fluorine
type: Class
subclass of: element
disjoint with: neodymium
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium

hydrophilic space between lipid bilayers
type: Class
subclass of: core site
subclass of: Restriction
  on property: part of
  some values from: multilamellar vesicle
disjoint with: dendrimer core
disjoint with: hollow core of nanocapsule
disjoint with: nuclear core of nanocell
disjoint with: hollow core of nanoshell
disjoint with: hollow core of nanocage
disjoint with: hydrophobic core of micelle
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The aqueous space between lipid bilayers (e.g, in a multilamellar vesicle).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydrophilic space between lipid bilayers</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_260
preferred name: hydrophilic space between lipid bilayers

chitosan nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: chitosan
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of chitosan</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>chitosan nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_261
preferred name: chitosan nanoparticle

antiferromagnetic
type: Class
subclass of: magnetic
comment: (definition source): http://dictionary.reference.com/browse/antiferromagnetic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Magnetic property exhibited in materials where the magnetic moments of adjacent atoms align in opposite directions, and this quality exists only below the Neel temperature.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>antiferromagnetic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_262
preferred name: antiferromagnetic

glass
type: Class
equivalent class: Class
  intersection of: solid
  intersection of: Restriction
    on property: has quality
    some values from: glassy state
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A brittle transparent solid substance with irregular atomic structure.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>glass</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_263
preferred name: glass

carbohydrazide group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: carbohydrazide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=O)-N(-)-N(-)-. The group is characteristic of a carbohydrazide compound.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carbohydrazide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_264
preferred name: carbohydrazide group

Group 13 Element
type: Class
equivalent class: Class
  union of: boron
  union of: gallium
  union of: aluminium
  union of: indium
  union of: thallium
subclass of: group element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 13 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Group 13 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Group 13 Element
code: NPO_266
synonym: boron group element

neodymium
type: Class
subclass of: element
disjoint with: caesium
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton

ether group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: ether
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -O-. The group is characteristic of an ether in which the oxygen atom is attached to two carbon atoms via single covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ether group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_268
preferred name: ether group

nanoshell
type: Class
subclass of: three-dimensional nanoparticle
subclass of: Restriction
  on property: has quality
  some values from: spherical shape
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A three-dimensional nanoparticle which is composed of a spherical core surrounded by a shell of a few nanometer in thickness. If the shell is made of metal particles, then it is called a metallic nanoshell (e.g. Gold nanoshell).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanoshell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_270
preferred name: nanoshell

Group 6 Element
type: Class
equivalent class: Class
  union of: seaborgium
  union of: chromium
  union of: tungsten
  union of: molybdenum
subclass of: group element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 6 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Group 6 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Group 6 Element
code: NPO_271
synonym: chromium group element

three-dimensional nano-object
type: Class
subclass of: nano-object
synonym: 3-D nano-object
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A nano-object which has all three external dimensions in the nanoscale (between 1 and 1000 nm) range.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>three-dimensional nano-object</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_272
preferred name: three-dimensional nano-object

iron oxide
type: Class
subclass of: oxide
subclass of: Restriction
  on property: has quality
  some values from: inorganic
subclass of: Restriction
  on property: has part
  some values from: iron
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of iron.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>iron oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_273
preferred name: iron oxide

shape
type: Class
subclass of: independent general individual quality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Quality which exactly or approximately describes the external form or outline of something as distinct from its substance.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_274
comment: The spatial arrangement of something as distinct from its substance. [source: NCI, WordNet]
preferred name: shape

caesium
type: Class
subclass of: element
disjoint with: dubnium
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum

aromatic
type: Class
subclass of: independent specific individual quality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a chemical substance due to the presence of a cyclically conjugated molecular entity , with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>aromatic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: Definition of aromatic is based on that of an aromatic compound (CHEBI:33655)
code: NPO_276
comment: [definition source]: ChEBI
preferred name: aromatic

mercury atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: mercury
disjoint with: zinc atom
disjoint with: potassium atom
disjoint with: neptunium atom
disjoint with: chlorine atom
disjoint with: dubnium atom
disjoint with: radium atom
disjoint with: uranium atom
disjoint with: zirconium atom
disjoint with: rubidium atom
disjoint with: osmium atom
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom

secondary amine linkage
type: Class
subclass of: covalent linkage
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a secondary amine group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>secondary amine linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_278
preferred name: secondary amine linkage

dendrimer core
type: Class
subclass of: core
subclass of: Restriction
  on property: has part
  some values from: dendrimer cavity
subclass of: Restriction
  on property: part of
  some values from: dendrimer
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The core part of a dendrimer, which is formed by the core initiator group [npo:NPO_803].</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dendrimer core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_279
preferred name: dendrimer core

Group 14 Element
type: Class
equivalent class: Class
  union of: germanium
  union of: lead
  union of: silicon
  union of: tin
  union of: carbon
subclass of: group element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 14 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Group 14 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Group 14 Element
code: NPO_280
synonym: carbon group element

anticancer drug role
type: Class
subclass of: molecular role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Role of a molecular entity, which brings about an end therapeutic result in cancer therapy.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>anticancer drug role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_281
preferred name: anticancer drug role

dubnium
type: Class
subclass of: element
disjoint with: gallium
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium

mixture
type: Class
equivalent class: Class
  intersection of: chemical substance
  intersection of: Restriction
    on property: has quality
    some values from: state of mixture
subclass of: Restriction
  on property: has quality
  some values from: volume
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A chemical substance which is composed of two or more substances (with variable composition) that are not chemically combined with each other and are capable of being separated hy physical means.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>mixture</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_283
preferred name: mixture

two-dimensional nanoparticle
type: Class
subclass of: nanoparticle
synonym: 2-D nanoparticle
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has two external dimensions in the nanoscale size range.</ncicp:def-definition><ncicp:Definition_Review_Date>110104</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>two-dimensional nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_284
preferred name: two-dimensional nanoparticle

spherical shape
type: Class
subclass of: ellipsoidal shape
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An ellipsoidal shape inhering in 3-dimensional object, where every point on the surface is equidistant from the center of the object.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>spherical shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_286
synonym: spherical
preferred name: spherical shape

gallium
type: Class
subclass of: element
disjoint with: tantalum
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium

tantalum
type: Class
subclass of: element
disjoint with: aluminium
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium

reagent
type: Class
equivalent class: Class
  intersection of: Restriction
    on property: has role
    some values from: Class
      intersection of: reagent role
      intersection of: Restriction
        on property: is realized in
        some values from: chemical reaction
  intersection of: Restriction
    on property: participates in
    some values from: chemical reaction
subclass of: compound for material synthesis
subclass of: Restriction
  on property: has quality
  some values from: physical state
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A substance or compound, which is used to produce a chemical reaction, to detect, measure, or produce other substances; or to convert one substance into another by chemical reaction.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>reagent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_290
preferred name: reagent

hydrazone linkage between carbohydrazide and aldehyde
type: Class
subclass of: hydrazone linkage
subclass of: Restriction
  on property: derives from
  some values from: carbohydrazide group
subclass of: Restriction
  on property: derives from
  some values from: aldehyde group
subclass of: Restriction
  on property: part of
  some values from: hydrazone group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrazone linkage which is formed between a carbohydrazide and an aldehyde, through covalent interactions between atoms of respective functional groups..</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydrazone linkage between carbohydrazide and aldehyde</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_291
preferred name: hydrazone linkage between carbohydrazide and aldehyde

reagent role
type: Class
subclass of: role
subclass of: Restriction
  on property: role of
  some values from: reagent
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Role played by a substance or compound used to produce a chemical reaction to detect, measure, or produce other substances.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>reagent role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_292
DB xref ID: obo:OBI_0000086
preferred name: reagent role

drug that affects protein activity related to DNA synthesis
type: Class
subclass of: drug directed against tumor DNA
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that is directed against a tumor cell to inhibit a protein activity related to the synthesis of DNA.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>drug that affects protein activity related to DNA synthesis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_294
preferred name: drug that affects protein activity related to DNA synthesis

sulfonamide linkage between primary amine and sulfonyl chloride derivative
type: Class
subclass of: sulfonamide linkage
subclass of: Restriction
  on property: derives from
  some values from: sulfonyl chloride group
subclass of: Restriction
  on property: part of
  some values from: sulfonamide group
subclass of: Restriction
  on property: derives from
  some values from: primary amine group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A sulfonamide linkage which is formed between a primary amine and a suflonyl chloride derivative, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>sulfonamide linkage between primary amine and sulfonyl chloride derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_295
preferred name: sulfonamide linkage between primary amine and sulfonyl chloride derivative

cellular uptake of extracellular material
type: Class
subclass of: cellular process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A biological process or mechanism by which extracellular materials are taken up by a cell.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cellular uptake of extracellular material</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_296
preferred name: cellular uptake of extracellular material

zinc atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: zinc
disjoint with: potassium atom
disjoint with: neptunium atom
disjoint with: chlorine atom
disjoint with: dubnium atom
disjoint with: radium atom
disjoint with: uranium atom
disjoint with: zirconium atom
disjoint with: rubidium atom
disjoint with: osmium atom
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom

potassium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: potassium
disjoint with: neptunium atom
disjoint with: chlorine atom
disjoint with: dubnium atom
disjoint with: radium atom
disjoint with: uranium atom
disjoint with: zirconium atom
disjoint with: rubidium atom
disjoint with: osmium atom
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom

double-walled carbon nanotube
type: Class
subclass of: double-walled nanotube
subclass of: Restriction
  on property: has part
  some values from: carbon
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A double-walled nanotube which consists of two graphite layers or sheets of hexagonal arrays of carbon, rolled into two concentric seamless cylinders with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>double-walled carbon nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_301
preferred name: double-walled carbon nanotube

neptunium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: neptunium
disjoint with: chlorine atom
disjoint with: dubnium atom
disjoint with: radium atom
disjoint with: uranium atom
disjoint with: zirconium atom
disjoint with: rubidium atom
disjoint with: osmium atom
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom

chlorine atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 17
disjoint with: dubnium atom
disjoint with: radium atom
disjoint with: uranium atom
disjoint with: zirconium atom
disjoint with: rubidium atom
disjoint with: osmium atom
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom

zinc sulfide
type: Class
subclass of: inorganic compound or molecule
subclass of: Restriction
  on property: has part
  some values from: sulfur
subclass of: Restriction
  on property: has part
  some values from: zinc
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An inorganic compound or molecule which is composed of zinc and sulfur.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>zinc sulfide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_306
preferred name: zinc sulfide

disc-shaped
type: Class
subclass of: cylindrical shape
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cylindrical shape inhering in 3-dimensional object with height smaller than the cross-sectional diameter.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>disc-shaped</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_307
preferred name: disc-shaped
synonym: disclike
synonym: disk-shaped
synonym: disklike

anticancer drug directed against endothelial growth factor
type: Class
subclass of: anticancer drug directed against endothelium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that is directed to affect the synthesis and function of endothelial growth factor.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>anticancer drug directed against endothelial growth factor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_308
preferred name: anticancer drug directed against endothelial growth factor

period element
type: Class
subclass of: periodic table element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element that has the same number of electron shells as other elements of a horizontal row in the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>period element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_310
preferred name: period element

amide linkage between primary amine and acid anhydride
type: Class
subclass of: amide linkage
subclass of: Restriction
  on property: derives from
  some values from: acid anhydride group
subclass of: Restriction
  on property: derives from
  some values from: primary amine group
subclass of: Restriction
  on property: part of
  some values from: carboxamide group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide linkage which is formed between a primary amine and an acid anhydride.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>amide linkage between primary amine and acid anhydride</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_311
preferred name: amide linkage between primary amine and acid anhydride

anticancer drug
type: Class
equivalent class: Class
  intersection of: compound for therapy
  intersection of: Restriction
    on property: has role
    some values from: anticancer drug role
subclass of: Restriction
  on property: has function
  some values from: therapeutic function
subclass of: Restriction
  on property: has property
  some values from: pharmacokinetic property
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which has the intended function to furnish pharmacological activity or other direct effect in the cure, mitigation, treatment or prevention of cancer.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>anticancer drug</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C1909
code: NPO_312
preferred name: anticancer drug
synonym: chemotherapeutic agent
synonym: drug
synonym: therapeutic agent

intramolecular interaction
type: Class
subclass of: chemical interaction
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An attractive type of chemical interaction that holds atoms together in a molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>intramolecular interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_313
preferred name: intramolecular interaction

aluminium
type: Class
subclass of: element
disjoint with: polonium
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium

tubulin binding agent
type: Class
equivalent class: Class
  intersection of: antimitotic agent
  intersection of: Restriction
    on property: has function
    some values from: Class
      intersection of: binding function
      intersection of: Restriction
        on property: is realized in
        some values from: tubulin binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antimitotic agent, which binds to tubulin and inhibits its action.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tubulin binding agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C25974
code: NPO_315
preferred name: tubulin binding agent

hollow core of nanocapsule
type: Class
subclass of: core site
subclass of: Restriction
  on property: part of
  some values from: Nanocapsule
disjoint with: nuclear core of nanocell
disjoint with: hollow core of nanoshell
disjoint with: hollow core of nanocage
disjoint with: hydrophobic core of micelle
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The hollow core region of a nanocapsule.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hollow core of nanocapsule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_317
preferred name: hollow core of nanocapsule

polonium
type: Class
subclass of: element
disjoint with: manganese
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium

metastasis
type: Class
subclass of: pathologic process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Metastasis is the spread or migration of cancer cells from one part of the body (the organ in which it first appeared) to another. The secondary tumor contains cells that are like those in the original (primary) tumor. For example, breast cancer cells may spread (metastasize) to the lungs and cause the growth of a new tumor. When this happens, the disease is called metastatic breast cancer. (NCI)</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>metastasis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C19151
code: NPO_319
preferred name: metastasis
synonym: tumor cell migration

spheroidal shape
type: Class
subclass of: ellipsoidal shape
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An ellipsoidal shape, which is generated by half-revolution of an ellipse around its major axis or minor axis.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>spheroidal shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_320
preferred name: spheroidal shape

isocyanate group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: isocyanate compound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -N=C=O. The group is characteristic of a isocyanate compounds wherein it is attached to an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>isocyanate group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_321
preferred name: isocyanate group

lipid membrane
type: Class
subclass of: supramolecular entity
subclass of: Restriction
  on property: has part
  some values from: lipid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A supramolecular structure which is a membrane composed of lipid molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>lipid membrane</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_322
preferred name: lipid membrane

dubnium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: dubnium
disjoint with: radium atom
disjoint with: uranium atom
disjoint with: zirconium atom
disjoint with: rubidium atom
disjoint with: osmium atom
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom

manganese
type: Class
subclass of: element
disjoint with: neon
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium

contrast agent
type: Class
subclass of: diagnostic imaging agent
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A diagnostic imaging agent, which is used during an imaging procedure to allow the delineation of biological structures in their images. Contrast agents appear opaque due to the difference in absorption of X-rays or other electromagnetic waves and surrounding tissue.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>contrast agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C390
code: NPO_325
preferred name: contrast agent

diazonium group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: diazonium compound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -[N+]#N. The group is characteristic of diazonium compounds.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>diazonium group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_326
preferred name: diazonium group

DNA-RNA transcription regulator
type: Class
equivalent class: Class
  intersection of: antineoplastic agent
  intersection of: Restriction
    on property: has role
    some values from: Class
      intersection of: regulator role
      intersection of: Restriction
        on property: is realized in
        some values from: regulation of DNA-dependent transcription
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic agent,which regulates DNA-dependent transcription.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>DNA-RNA transcription regulator</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: DNA-RNA transcription regulator
code: NPO_327

neon
type: Class
subclass of: element
disjoint with: chromium
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium

diazonium compound
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: diazonium group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A diazonium compound is an organic compound which is characterized by the presence of a diazonium group. It has the structure R-[N+]#N, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>diazonium compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_330
preferred name: diazonium compound

ferrimagnetic
type: Class
subclass of: magnetic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Magnetic property exhibited by materials in presence of an external magnetic field and in these materials the magnetic moment of the atoms on different sublattices are opposed, and the opposing magnetic moments are unequal, and therefore, a spontaneous magnetization remains. This property exists below the Curie temperature.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ferrimagnetic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_331
preferred name: ferrimagnetic

Lanthanide
type: Class
equivalent class: Class
  union of: dysprosium
  union of: neodymium
  union of: samarium
  union of: gadolinium
  union of: holmium
  union of: europium
  union of: praseodymium
  union of: cerium
  union of: promethium
  union of: terbium
  union of: erbium
  union of: ytterbium
  union of: lanthanum
  union of: thulium
  union of: lutetium
subclass of: inner transition element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An inner transition element which is any element with atomic numbers 57 (lanthanum) to 71 (Lutetium).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Lanthanide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Lanthanide
code: NPO_332

radium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: radium
disjoint with: uranium atom
disjoint with: zirconium atom
disjoint with: rubidium atom
disjoint with: osmium atom
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom

chromium
type: Class
subclass of: element
disjoint with: samarium
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine

uranium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 92
disjoint with: zirconium atom
disjoint with: rubidium atom
disjoint with: osmium atom
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom

supramolecular entity
type: Class
subclass of: molecular entity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which is formed and held together by non-covalent interactions of molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>supramolecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_337
preferred name: supramolecular entity

lipid bilayer
type: Class
subclass of: lipid membrane
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A lipid membrane which is two (lipid) molecules thick.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>lipid bilayer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: MESH: D008051
code: NPO_338
preferred name: lipid bilayer

bromo group
type: Class
subclass of: halo group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A halo group in which the halogen atom is a bromine atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>bromo group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_339
preferred name: bromo group

imidoester compound
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: imidoester group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imidoester compound is an organic compound which is characterized by the presence of an imidoester group. It has the structure R-C(=[NH2]+)-O-CH3, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>imidoester compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_340
preferred name: imidoester compound

zirconium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 40
disjoint with: rubidium atom
disjoint with: osmium atom
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom

circular shape
type: Class
subclass of: elliptical shape
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An elliptical shape in which the two foci are coincident that it is formed by a closed curve that is the path, traced by a point moving in a plane so that its distance from a fixed point (the circle's center) is a constant.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>circular shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_342
comment: [definition based on source]:http://www.cycfoundation.org, http://www.thefreedictionary.com, NCI
synonym: circular
preferred name: circular shape

dipole-induced dipole interaction
type: Class
subclass of: dipole-dipole interaction
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dipole-dipole interaction between a polar molecule and a non-polar molecule due to attraction between permanent dipole on the polar molecule and temporary dipole on the non-polar molecule; the temporary dipole on the non-polar molecule is induced by the permanent dipole on the polar molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dipole-induced dipole interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: It occurs when a non-polar molecule dissolves in a polar or a dipolar solvent under the assumption that the solute dissolves because the attractive force between the solvent and solute are stronger than the intermolecular forces, holding the non-polar solute molecules together.
code: NPO_343
preferred name: dipole-induced dipole interaction

aryl halide group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: aryl halide
subclass of: Restriction
  on property: has part
  some values from: halo group
subclass of: Restriction
  on property: has part
  some values from: aryl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which consists of an aromatic ring bonded to one or more halogen atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>aryl halide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_344
preferred name: aryl halide group

aziridine group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: aziridine derivative
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which consists of a nitrogen atom bonded to two adjacent carbon atoms in the form of a 3-membered saturated ring structure; it has the structure C1-C-N1. And the group is characteristic of any aziridine derivative.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>aziridine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_345
preferred name: aziridine group

rubidium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 37
disjoint with: osmium atom
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom

samarium
type: Class
subclass of: element
disjoint with: rubidium
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium

osmium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: osmium
disjoint with: mendelevium atom
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom

rubidium
type: Class
subclass of: element
disjoint with: berkelium
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 37.</ncicp:def-definition></ncicp:ComplexDefinition>

inorganic compound or molecule
type: Class
equivalent class: Class
  intersection of: compound by chemical composition
  intersection of: Restriction
    on property: has quality
    some values from: inorganic
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule, in which carbon is not the principal element.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>inorganic compound or molecule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_351
synonym: inorganic compound
preferred name: inorganic compound or molecule
synonym: inorganic molecule

mendelevium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: mendelevium
disjoint with: praseodymium atom
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom

multi-walled carbon nanotube
type: Class
subclass of: multi-walled nanotube
subclass of: Restriction
  on property: has part
  some values from: carbon
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A multi-walled nanotube which consists of multiple graphite layers or sheets of hexagonal arrays of carbon, rolled in on themselves to form concentric seamless cylinders with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>multi-walled carbon nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: MWCNT
code: NPO_354
preferred name: multi-walled carbon nanotube

nanoparticle response to ultrasound
type: Class
subclass of: nanoparticle response to external stimulus
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to external stimulus, which occurs in response to ultrasound.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanoparticle response to ultrasound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_356
preferred name: nanoparticle response to ultrasound

alpha-aminoacid sidechain
type: Class
subclass of: group
subclass of: Restriction
  on property: part of
  some values from: aminoacid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A group that forms the sidechain of an alpha-aminoacid.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>alpha-aminoacid sidechain</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_357
preferred name: alpha-aminoacid sidechain

Group 4 Element
type: Class
equivalent class: Class
  union of: zirconium
  union of: rutherfordium
  union of: titanium
  union of: hafnium
subclass of: group element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 4 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Group 4 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Group 4 Element
code: NPO_358
synonym: titanium group element

berkelium
type: Class
subclass of: element
disjoint with: bohrium
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 97.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>berkelium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>

colloid
type: Class
equivalent class: Class
  intersection of: suspension
  intersection of: Restriction
    on property: has quality
    some values from: colloidal state
subclass of: Restriction
  on property: has part
  some values from: continuous phase
subclass of: Restriction
  on property: has part
  some values from: dispersed phase
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A suspension of particles (dispersed phase) in a liquid medium (dispersion medium or continuous phase).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>colloid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C32345
code: NPO_360
preferred name: colloid

core site
type: Class
equivalent class: Class
  intersection of: material site
  intersection of: Restriction
    on property: part of
    some values from: core
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A material site which is in the core of a material entity; which is hollow or a void space, into which molecular agents like drugs, imaging agents, etc. can be placed.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>core site</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_363
preferred name: core site

praseodymium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: praseodymium
disjoint with: hafnium atom
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom

hafnium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 72
disjoint with: bismuth atom
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom

bohrium
type: Class
subclass of: element
disjoint with: phosphorus
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 107.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>bohrium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_368

bismuth atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 83
disjoint with: strontium atom
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom

aziridine derivative
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: aziridine group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aziridine derivative is an organic compound which is characterized by the presence of an aziridine group. It has the structure R-C1H-CH2-C1H, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>aziridine derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_370
preferred name: aziridine derivative

phosphorus
type: Class
subclass of: element
disjoint with: gadolinium
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 15.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>phosphorus</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_371
preferred name: phosphorus

linkage between primary amine and isothiocyanate
type: Class
subclass of: isothiourea linkage
subclass of: Restriction
  on property: derives from
  some values from: isothiocyanate group
subclass of: Restriction
  on property: derives from
  some values from: primary amine group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An isothiourea linkage which is formed between a primary amine and an isothiocyanate, through covalent interactions between atoms of respective functional groups..</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>linkage between primary amine and isothiocyanate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_372
preferred name: linkage between primary amine and isothiocyanate

strontium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: strontium
disjoint with: tin atom
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom

Group 15 Element
type: Class
equivalent class: Class
  union of: nitrogen
  union of: phosphorus
  union of: antimony
  union of: arsenic
  union of: bismuth
subclass of: group element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 15 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Group 15 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Group 15 Element
code: NPO_375
synonym: pnictogen

isourea linkage between primary amine and isocyanate
type: Class
subclass of: isourea linkage
subclass of: Restriction
  on property: derives from
  some values from: isocyanate group
subclass of: Restriction
  on property: derives from
  some values from: primary amine group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An isourea linkage which is formed between a primary amine and an isocyanate, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>isourea linkage between primary amine and isocyanate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_376
preferred name: isourea linkage between primary amine and isocyanate

tin atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 50
disjoint with: rhodium atom
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom

rhodium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: rhodium
disjoint with: ruthenium atom
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom

optical imaging contrast agent
type: Class
subclass of: contrast agent
subclass of: Restriction
  on property: has quality
  some values from: optical quality
subclass of: Restriction
  on property: has application
  some values from: optical imaging
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A contrast agent, which has optical properties, and provides contrast in images captured using optical imaging techniques.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>optical imaging contrast agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_379
preferred name: optical imaging contrast agent

gadolinium
type: Class
subclass of: element
disjoint with: holmium
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 64.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gadolinium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_380
preferred name: gadolinium

ruthenium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: ruthenium
disjoint with: lawrencium atom
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom

nanowire
type: Class
subclass of: two-dimensional nano-object
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A two-dimensional nano-object which has a wire-like structure made of materials that exhibit unique electrical and optical properties.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanowire</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C62376
code: NPO_383
preferred name: nanowire

holmium
type: Class
subclass of: element
disjoint with: barium
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 67.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>holmium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_385
preferred name: holmium

hydrophobic interaction
type: Class
subclass of: non-covalent interaction
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A non-covalent interaction which is a repulsive interaction between hydrophobic molecule or hydrophobic part of an amphiphilic molecule and water molecules in aqueous solutions. It results from energetically favorable interactions between hydrophilic molecules or parts there of and water molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydrophobic interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_388
preferred name: hydrophobic interaction

arylamine linkage between primary amine and fluorobenzene derivative
type: Class
subclass of: arylamine linkage
subclass of: Restriction
  on property: derives from
  some values from: fluorobenzene group
subclass of: Restriction
  on property: derives from
  some values from: primary amine group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An arylamine linkage which is formed between a primary amine and a fluorobenzene derivative, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>arylamine linkage between primary amine and fluorobenzene derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_389
preferred name: arylamine linkage between primary amine and fluorobenzene derivative

pyrimidine antagonist
type: Class
subclass of: antineoplastic antimetabolite
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic antimetabolite which affects the metabolism and utilization of pyrimidines.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>pyrimidine antagonist</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C1557
code: NPO_390
preferred name: pyrimidine antagonist

carboxamidine group
type: Class
subclass of: amidine group
subclass of: Restriction
  on property: part of
  some values from: carboxamidine
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amidine group which has the structure -C(=N-)-NH2. It is characteristic of a carboxamidine compound.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carboxamidine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_391
preferred name: carboxamidine group

nanoemulsion
type: Class
equivalent class: Class
  intersection of: nanoparticle formulation
  intersection of: Restriction
    on property: has quality
    some values from: state of emulsion
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle formulation which exists as an emulsion and contains nanoparticles as the dispersed phase.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanoemulsion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C62369
code: NPO_393
preferred name: nanoemulsion
synonym: nanoparticle emulsion

imide group
type: Class
subclass of: amide group
subclass of: Restriction
  on property: part of
  some values from: imide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide group which has the structure -C(=O)-N(-[*])-C(=O)-. The group is characteristic of an imide compound.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>imide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_394
preferred name: imide group

drug-loaded nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: Class
      intersection of: anticancer drug
      intersection of: Restriction
        on property: has role
        some values from: payload agent role
subclass of: Restriction
  on property: has property
  some values from: pharmacokinetic property
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is loaded with a drug.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>drug-loaded nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_395
preferred name: drug-loaded nanoparticle

lawrencium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: lawrencium
disjoint with: lithium atom
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom

double-walled nanotube
type: Class
subclass of: nanotube
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanotube which consists of two layers or sheets of hexagonal arrays of an element or molecule, rolled into two concentric seamless cylinders with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>double-walled nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_398
preferred name: double-walled nanotube

lithium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 3
disjoint with: boron atom
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom

gold nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: gold
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of gold element.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gold nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: Au nanoparticle
code: NPO_401
preferred name: gold nanoparticle

cyanate
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: cyanate group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cyanate is an organic compound which is characterized by the presence of a cyanate group. It has the structure R-O-C#N, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cyanate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_402
preferred name: cyanate

boron atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 5
disjoint with: yttrium atom
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 5.</ncicp:def-definition></ncicp:ComplexDefinition>

yttrium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: yttrium
disjoint with: hydrogen atom
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 39.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>yttrium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>

acyl azide group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: has part
  some values from: acyl group
subclass of: Restriction
  on property: part of
  some values from: acyl azide
subclass of: Restriction
  on property: has part
  some values from: diazonium group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure R-C(=O)-[N+]#N, where R denotes any organic group. The group is characteristic of acyl azide compounds.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>acyl azide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_405
comment: The structure of an acyl azide is R-C(=O)-[N+]#N, in which an acyl group is bound to a diazonium group.
preferred name: acyl azide group

nuclear core of nanocell
type: Class
subclass of: core site
subclass of: Restriction
  on property: part of
  some values from: nanocell
disjoint with: hollow core of nanoshell
disjoint with: hollow core of nanocage
disjoint with: hydrophobic core of micelle
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The central part of a nanocell.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nuclear core of nanocell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_407
preferred name: nuclear core of nanocell

f-block element
type: Class
subclass of: block element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electrons occupy f-orbitals.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>f-block element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_408
preferred name: f-block element

epidermal growth factor receptor tyrosine kinase inhibitor
type: Class
subclass of: tyrosine kinase inhibitor
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Tyrosine kinase inhibitor, which inhibits Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase, involved with signal transduction pathways, and may be useful in treating tumors that over express EGFR. [source:NCI_Thesaurus]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>epidermal growth factor receptor tyrosine kinase inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: EGFR-TK inhibitor
DB xref ID: NCIT: C2167
code: NPO_409
preferred name: epidermal growth factor receptor tyrosine kinase inhibitor

polar
type: Class
subclass of: polarity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality that inheres in a molecule or chemical bond due to the presence of dipole moments.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>polar</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_410
preferred name: polar

one-dimensional nano-object
type: Class
subclass of: nano-object
synonym: 1-D nano-object
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A nano-object which has only one external dimension in the nanoscale (between 1 and 1000 nm) range.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>one-dimensional nano-object</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_411
preferred name: one-dimensional nano-object

stimulus of light
type: Class
subclass of: external stimulus for nanoparticle function
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by light.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>stimulus of light</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_412
synonym: stimulus of electromagnetic radiation
preferred name: stimulus of light

barium
type: Class
subclass of: element
disjoint with: copper
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 56.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>barium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_413
preferred name: barium

thioether linkage between thiol and acryloyl compound
type: Class
subclass of: thioether linkage
subclass of: Restriction
  on property: derives from
  some values from: sulfhydryl group
subclass of: Restriction
  on property: derives from
  some values from: acryloyl group
subclass of: Restriction
  on property: part of
  some values from: thioether group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thioether linkage which is formed between a thiol and an acryloyl compound, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thioether linkage between thiol and acryloyl compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_414
preferred name: thioether linkage between thiol and acryloyl compound

hydrazone linkage between carbohydrazide and ketone
type: Class
subclass of: hydrazone linkage
subclass of: Restriction
  on property: derives from
  some values from: ketone group
subclass of: Restriction
  on property: derives from
  some values from: carbohydrazide group
subclass of: Restriction
  on property: part of
  some values from: hydrazone group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrazone linkage which is formed between a carbohydrazide and a ketone, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydrazone linkage between carbohydrazide and ketone</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_416
preferred name: hydrazone linkage between carbohydrazide and ketone

hydrogen atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: hydrogen
disjoint with: helium atom
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 1.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydrogen atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_418

copper
type: Class
subclass of: element
disjoint with: lead
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 29.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>copper</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_419
preferred name: copper

inner transition element
type: Class
equivalent class: Class
  intersection of: f-block element
  intersection of: Class
    union of: Actinide
    union of: Lanthanide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A metal which is either an actinide or a lanthanide.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>inner transition element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_420
preferred name: inner transition element

electronegativity
type: Class
subclass of: realizable_entity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity that describes the ability of an atom in a molecule to draw bonding electrons to itself.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>electronegativity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_421
comment: [definition source]: http://hyperphysics.phy-astr.gsu.edu/Hbase/hframe.html
preferred name: electronegativity

lead
type: Class
subclass of: element
disjoint with: rhenium
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 51.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>lead</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_424
preferred name: lead

rhenium
type: Class
subclass of: element
disjoint with: indium
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 75.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>rhenium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_425
preferred name: rhenium

iodo group
type: Class
subclass of: halo group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A halo group in which the halogen atom is a iodine atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>iodo group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_426
preferred name: iodo group

ionizable
type: Class
subclass of: ionizability
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A qualitative measure of "ionizability" which indicates that the bearer can be ionized to gain negative or positive charges.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ionizable</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_428
preferred name: ionizable

carbonate ester
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: carbonate ester group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carbonate ester is an organic compound which is a diester derivative of carbonate and it is characterized by the presence of a "carbonate ester group." It has the structure R-O-C(=O)-O-R', where R, R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carbonate ester</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_429
synonym: carbonate compound
preferred name: carbonate ester

hydrazone linkage
type: Class
subclass of: covalent linkage
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a hydrazone group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydrazone linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_430
preferred name: hydrazone linkage

maleimide group
type: Class
subclass of: imide group
subclass of: Restriction
  on property: part of
  some values from: maleimide derivative
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imide group derived from maleimide by the removal of a hydrogen atom that was attached to nitrogen atom of the parent maleimide. The group is characteristic of any maleimide derivative.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>maleimide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_431
preferred name: maleimide group

indium
type: Class
subclass of: element
disjoint with: silicon
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 49.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>indium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_432
preferred name: indium

multilamellar vesicle
type: Class
subclass of: liposome
disjoint with: unilamellar vesicle
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A liposome vesicle that has more than one lipid bilayer, and the bilayers are separated by hydrophilic spaces.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>multilamellar vesicle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_433
preferred name: multilamellar vesicle

thalidomide
type: Class
subclass of: organic compound or molecule
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: therapeutic function
    intersection of: Restriction
      on property: is realized in
      some values from: antineoplastic activity
subclass of: Restriction
  on property: has role
  some values from: anticancer drug role
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: therapeutic function
    intersection of: Restriction
      on property: is realized in
      some values from: tumor angiogenesis inhibition
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: inhibitor role
    intersection of: Restriction
      on property: is realized in
      some values from: inhibition of tumor necrosis factor biosynthetic process
synonym: 2-(2,6-dioxopiperidin-3-yl) isoindoline-1,3-dione [source: IUPAC]
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A synthetic derivative of glutamic acid (alpha-phthalimido-glutarimide) with teratogenic, immunomodulatory, anti-inflammatory and anti-angiogenic properties. Thalidomide acts primarily by inhibiting both the production of tumor necrosis factor alpha (TNF-alpha) in stimulated peripheral monocytes and the activities of interleukins and interferons. This agent also inhibits polymorphonuclear chemotaxis and monocyte phagocytosis. In addition, thalidomide inhibits pro-angiogenic factors such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), thereby inhibiting angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thalidomide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: Anticancer Drug Directed Against Endothelial Growth Factor Receptor
DB xref ID: NCIT: C870
code: NPO_434
preferred name: thalidomide

thymidylate synthase inhibitor
type: Class
equivalent class: Class
  intersection of: enzyme inhibitor drug
  intersection of: Restriction
    on property: has role
    some values from: Class
      intersection of: inhibitor role
      intersection of: Restriction
        on property: is realized in
        some values from: inhibition of thymidylate synthase activity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An enzyme inhibitor, which inhibits thymidylate synthase, an enzyme that catalyses the de novo synthesis of deoxythymidylate and acts as a key rate-limiting enzyme of DNA synthesis.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thymidylate synthase inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_435
preferred name: thymidylate synthase inhibitor
synonym: thymidylate synthetase inhibitor

anticancer drug that modifies expression of specific genes
type: Class
subclass of: drug directed against tumor DNA
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that is directed against a tumor cell to modify the expression of specific genes.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Anticancer drug that modifies expression of specific genes</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Anticancer drug that modifies expression of specific genes
code: NPO_437

helium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: helium
disjoint with: krypton atom
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 2.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>helium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_438
preferred name: helium atom

silicon
type: Class
subclass of: element
disjoint with: palladium
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 14.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>silicon</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_439
preferred name: silicon

lectin inhibitor
type: Class
subclass of: anti-adhesion agent
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anti-adhesion agent, which inhibits lectin, a protein that binds carbohydrate on cell surfaces and causes cell agglutination.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>lectin inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C2120
code: NPO_440
preferred name: lectin inhibitor

fluorobenzene derivative
type: Class
equivalent class: Class
  intersection of: aryl halide
  intersection of: Restriction
    on property: has part
    some values from: fluorobenzene group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aryl halide derived from fluorobenzene.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fluorobenzene derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_441
preferred name: fluorobenzene derivative

enzyme inhibitor drug
type: Class
equivalent class: Class
  intersection of: antineoplastic agent
  intersection of: Restriction
    on property: has role
    some values from: Class
      intersection of: inhibitor role
      intersection of: Restriction
        on property: is realized in
        some values from: enzyme inhibition
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic agent, which binds to an enzyme and decreases or blocks the enzyme's activity by hindering the normal substrate-enzyme combination and the catalytic reaction.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>enzyme inhibitor drug</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: MESH: D004791
DB xref ID: NCIT: C471
code: NPO_442
comment: Only those enzyme inhibitors that are used as cancer drugs should be included under this class.
synonym: enzyme antagonist
synonym: enzyme inhibitor
preferred name: enzyme inhibitor drug

krypton atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: krypton
subclass of: Restriction
  on property: is integral part of
  all values from: krypton
disjoint with: ytterbium atom
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 36.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>krypton atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_443
preferred name: krypton atom

Group 17 Element
type: Class
equivalent class: Class
  union of: chlorine
  union of: iodine
  union of: fluorine
  union of: astatine
  union of: bromine
subclass of: group element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 17 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Group 17 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Group 17 Element
code: NPO_446
synonym: halogen

nanopipette
type: Class
subclass of: two-dimensional nano-object
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A two-dimensional nano-object which is a capillary tube with diameter in the nanometer range. Nanopipettes made from standard quartz capillary tubes are known to detect single molecules which are labeled with gold nanoparticles.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanopipette</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_447
preferred name: nanopipette

alkali metal
type: Class
equivalent class: Class
  union of: francium
  union of: caesium
  union of: rubidium
  union of: potassium
  union of: lithium
  union of: sodium
subclass of: metal
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of group 1 (IUPAC style) of the periodic table: lithium (Li), sodium (Na), potassium (K), rubidium (Rb), caesium (Cs), and francium (Fr).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>alkali metal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_448
preferred name: alkali metal

isothiocyanate group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: isothiocyanate
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -N=C=S. The group is characteristic of an isothiocyanate compound wherein it is attached to an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>isothiocyanate group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_449
preferred name: isothiocyanate group

thioester linkage
type: Class
subclass of: covalent linkage
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a thioester group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thioester linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_451
preferred name: thioester linkage

gold nanocantilever
type: Class
equivalent class: Class
  intersection of: nanocantilever
  intersection of: Restriction
    on property: has component part
    some values from: gold
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanocantilever which is composed of gold.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gold nanocantilever</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_453
preferred name: gold nanocantilever

palladium
type: Class
subclass of: element
disjoint with: vanadium
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 46.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>palladium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_455
preferred name: palladium

carbamate ester linkage
type: Class
subclass of: covalent linkage
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a carbamate ester group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carbamate ester linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_456
preferred name: carbamate ester linkage
synonym: carbamate linkage

nanohorn
type: Class
subclass of: two-dimensional nanoparticle
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A two-dimensional nanoparticle which resembles a fullerene-like nanostructure and exhibits an irregular horn-like shape.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanohorn</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C62386
code: NPO_457
comment: [NCI_Thesaurus definition]: A fullerene-like nanostructure that consists of graphene cylinders and exhibits an irregular horn-like shape.
preferred name: nanohorn

ytterbium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: ytterbium
subclass of: Restriction
  on property: atomic Number
  has value: 70
subclass of: Restriction
  on property: is integral part of
  all values from: ytterbium
disjoint with: samarium atom
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 70.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ytterbium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_458
preferred name: ytterbium atom

other metal
type: Class
equivalent class: Class
  union of: gallium
  union of: aluminium
  union of: lead
  union of: indium
  union of: thallium
  union of: bismuth
  union of: tin
subclass of: metal
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A metal which is any of the following elements: aluminium, bismuth, gallium, indium, lead, hallium, tin.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>other metal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_459
preferred name: other metal
synonym: poor metal

folate antagonist
type: Class
equivalent class: Class
  intersection of: antineoplastic antimetabolite
  intersection of: Restriction
    on property: has role
    some values from: Class
      intersection of: antagonist role
      intersection of: Restriction
        on property: is realized in
        some values from: inhibition of folic acid metabolism
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic antimetabolite which interferes with folic acid metabolism by inhibiting one or more folate-dependent enzymes, resulting in decreased DNA, RNA and protein synthesis. It has a chemical structure similar to folic acid, a key component in cell proliferation,</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>folate antagonist</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C511
code: NPO_460
synonym: antifolate
preferred name: folate antagonist
synonym: folate inhibitor
synonym: folic acid antagonist
synonym: folic acid inhibitor

rod-shaped
type: Class
subclass of: cylindrical shape
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cylindrical shape inhering in a 3-dimensional object having height greater than the cross-sectional diameter.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>rod-shaped</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C64352
code: NPO_461
preferred name: rod-shaped
synonym: rodlike

Group 18 Element
type: Class
equivalent class: Class
  union of: radon
  union of: neon
  union of: xenon
  union of: argon
  union of: helium
  union of: krypton
subclass of: group element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 18 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Group 18 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Group 18 Element
code: NPO_463
synonym: noble gas

etoposide-loaded nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: Class
      intersection of: etoposide
      intersection of: Restriction
        on property: has role
        some values from: payload agent role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is loaded with etoposide.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>etoposide-loaded nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_464
preferred name: etoposide-loaded nanoparticle

carboxylic ester linkage between organo hydroxy compound and acid anhydride
type: Class
subclass of: carboxylic ester linkage
subclass of: Restriction
  on property: derives from
  some values from: acid anhydride group
subclass of: Restriction
  on property: part of
  some values from: carboxylic ester group
subclass of: Restriction
  on property: derives from
  some values from: hydroxyl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carboxylic ester linkage which is formed between an organo hydroxy compound and an acid anhydride, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carboxylic ester linkage between organo hydroxy compound and acid anhydride</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_466
preferred name: carboxylic ester linkage between organo hydroxy compound and acid anhydride

samarium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: samarium
subclass of: Restriction
  on property: atomic Number
  has value: 62
subclass of: Restriction
  on property: is integral part of
  all values from: samarium
disjoint with: neodymium atom
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 62.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>samarium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_467
preferred name: samarium atom

molecular role
type: Class
subclass of: role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Role that inheres in or borne by an independent continuant at the molecular level in a particular context.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>molecular role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_468
preferred name: molecular role

peptide
type: Class
subclass of: organic compound or molecule
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic molecule or compound, which consists of two or more amino acids linked by covalent bonding between the amino group of one aminoacid and the carboxyl group of the other.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>peptide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_469
preferred name: peptide

anticancer drug acting in extracellular matrix
type: Class
subclass of: anticancer drug based on target
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that acts in the extracellular matrix</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>anticancer drug acting in extracellular matrix</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_470
preferred name: anticancer drug acting in extracellular matrix

entrapment
type: Class
subclass of: linkage
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A linkage in which a molecular structure or nanostructure becomes trapped due to non-covalent interactions, in a nanoparticle's material site that is partially bounded by the particle's constituting material.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>entrapment</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_471
preferred name: entrapment

hollow core of nanoshell
type: Class
subclass of: core site
subclass of: Restriction
  on property: part of
  some values from: nanoshell
disjoint with: hollow core of nanocage
disjoint with: hydrophobic core of micelle
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The hollow core of a nanoshell</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hollow core of nanoshell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_472
preferred name: hollow core of nanoshell

drug directed against protein of tumor cell
type: Class
subclass of: anticancer drug directed against tumor cell
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that is directed to interfere with the activity of a protein located at the tumor cell.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>drug directed against protein of tumor cell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_473
preferred name: drug directed against protein of tumor cell

neodymium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: neodymium
subclass of: Restriction
  on property: atomic Number
  has value: 60
subclass of: Restriction
  on property: is integral part of
  all values from: neodymium
disjoint with: meitnerium atom
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 60.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>neodymium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_474
preferred name: neodymium atom

group element
type: Class
subclass of: periodic table element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of a group of elements in the periodic table, which have similar outer shell electronic configurations of their respective atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>group element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_475
preferred name: group element

DNA intercalating agent
type: Class
equivalent class: Class
  intersection of: DNA binding agent
  intersection of: Restriction
    on property: has role
    some values from: Class
      intersection of: DNA intercalator role
      intersection of: Restriction
        on property: is realized in
        some values from: DNA intercalation
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A DNA binding agent that is capable of inserting itself between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore preventing its proper functioning.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>DNA intercalating agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: DNA intercalating agent
synonym: DNA intercalator
DB xref ID: NCIT: C582
code: NPO_476

stimulus of ultrasound
type: Class
subclass of: stimulus of sound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by ultrasound.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>stimulus of ultrasound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_477
preferred name: stimulus of ultrasound

Period 3 Element
type: Class
equivalent class: Class
  union of: chlorine
  union of: magnesium
  union of: aluminium
  union of: phosphorus
  union of: silicon
  union of: sulfur
  union of: argon
  union of: sodium
subclass of: period element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element in the third row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Period 3 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_478
preferred name: Period 3 Element

meitnerium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 109
subclass of: Restriction
  on property: is integral part of
  all values from: meitnerium
subclass of: Restriction
  on property: is integral part of
  some values from: meitnerium
disjoint with: gallium atom
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 109.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>meitnerium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_480
preferred name: meitnerium atom

small unilamellar vesicle
type: Class
subclass of: unilamellar vesicle
disjoint with: large unilamellar vesicle
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unilamellar vesicle, which has size less than 100 nm.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>small unilamellar vesicle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_481
preferred name: small unilamellar vesicle

gallium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: gallium
subclass of: Restriction
  on property: atomic Number
  has value: 31
subclass of: Restriction
  on property: is integral part of
  all values from: gallium
disjoint with: tungsten atom
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 31.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gallium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_483
preferred name: gallium atom

surface of micelle
type: Class
subclass of: material boundary
subclass of: Restriction
  on property: part of
  some values from: micelle
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Surface of a micelle formed from polar head groups of constituting amphiphilic molecules in a polar solvent.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>surface of micelle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_484
preferred name: surface of micelle

spacer
type: Class
subclass of: fiat material part
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A flexible molecular part that connects two other parts of the same molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>spacer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_485
comment: [definition source]: Wikipedia
preferred name: spacer
synonym: spacer arm

vanadium
type: Class
subclass of: element
disjoint with: darmstadtium
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 23.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>vanadium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_486
preferred name: vanadium

antineoplastic antimetabolite
type: Class
equivalent class: Class
  intersection of: antineoplastic agent
  intersection of: Restriction
    on property: has role
    some values from: Class
      intersection of: antimetabolite role
      intersection of: Restriction
        on property: is realized in
        some values from: negative regulation of DNA replication
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic agent that inhibits the biosynthesis of pyrimidine or purine nucleotides or mimic natural nucleotides so they interfere with their synthesis or function and subsequently interrupt DNA, RNA, and/or protein synthesis.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>antineoplastic antimetabolite</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: MESH:D000964
DB xref ID: NCIT:C272
code: NPO_487
synonym: antimetabolite
preferred name: antineoplastic antimetabolite

darmstadtium
type: Class
subclass of: element
disjoint with: thallium
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 110.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>darmstadtium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_488
preferred name: darmstadtium

solubility
type: Class
subclass of: realizable_entity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable property which inheres in a solid, liquid, or gaseous chemical substance by virtue of a certain amount of the bearer to have the ability to dissolve or not in a certain volume of a liquid solvent to form a homogeneous solution.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>solubility</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_489
DB xref ID: PATO:0001536
preferred name: solubility

immunogenic
type: Class
subclass of: realizable_entity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity that inheres in a material entity and indicates that the bearer has the ability to produce or elicit an immune response.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>immunogenic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_490
preferred name: immunogenic

ionic bonding
type: Class
subclass of: intramolecular interaction
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An intramolecular interaction between positive and negative ions which are formed by the transfer of one or more valence electrons from one atom to another atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ionic bonding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_491
preferred name: ionic bonding

tungsten atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 74
subclass of: Restriction
  on property: is integral part of
  all values from: tungsten
subclass of: Restriction
  on property: is integral part of
  some values from: tungsten
disjoint with: tantalum atom
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 74.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tungsten atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_492
preferred name: tungsten atom

receptor
type: Class
equivalent class: Class
  intersection of: protein
  intersection of: Restriction
    on property: has function
    some values from: Class
      intersection of: function
      intersection of: Restriction
        on property: is realized in
        some values from: receptor activity
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: binding function
    intersection of: Restriction
      on property: is realized in
      some values from: receptor binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A protein that is located on the cell surface, or in the cytoplasm, and which binds to, or responds to, a ligand with high specificity. [based on source: UniProtKB]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>receptor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C18106
code: NPO_493
preferred name: receptor

thallium
type: Class
subclass of: element
disjoint with: europium
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 81.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thallium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_495
preferred name: thallium

drug directed against protein in cytoplasm
type: Class
subclass of: drug directed against protein of tumor cell
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that is directed to interfere with the activity of a protein located in the tumor cell cytoplasm</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>drug directed against protein in cytoplasm</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_496
preferred name: drug directed against protein in cytoplasm

tantalum atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: tantalum
subclass of: Restriction
  on property: atomic Number
  has value: 73
subclass of: Restriction
  on property: is integral part of
  all values from: tantalum
disjoint with: antimony atom
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 73.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tantalum atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_497
preferred name: tantalum atom

paramagnetic
type: Class
subclass of: magnetic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Magnetic property exhibited in a material only when the material is kept in the presence of an externally applied magnetic field, and the magnetism disappears when the magnetic field is removed. The magnetic moments of the atoms are not aligned, and the behavior causes the material to be attracted to external magnetic fields. This behavior exists only above the Curie or Neel Temperature.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>paramagnetic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_498
preferred name: paramagnetic

solubility in water
type: Class
subclass of: solubility
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Solubility which describes the ability of a certain amount of solid, liquid or gaseous chemical substance to dissolve in a certain volume of water solvent.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>solubility in water</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_500
preferred name: solubility in water
synonym: water solubility

antimony atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: antimony
subclass of: Restriction
  on property: is integral part of
  some values from: antimony
subclass of: Restriction
  on property: atomic Number
  has value: 51
disjoint with: curium atom
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 51.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>antimony atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_501
preferred name: antimony atom

primary amine group
type: Class
subclass of: amine group
subclass of: Restriction
  on property: part of
  some values from: primary amine
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amine group which is formally derived by the removal of one hydrogen atom from ammonia, by virtue of which it has the structure -NH2. The group is characteristic of a primary amine molecule wherein it is attached to hydrocarbyl groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>primary amine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_502
preferred name: primary amine group

thioether linkage
type: Class
subclass of: covalent linkage
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a thioether group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thioether linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_504
preferred name: thioether linkage

acyl fluoride group
type: Class
subclass of: acyl halide group
subclass of: Restriction
  on property: has part
  some values from: fluoro group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acyl halide group in which the halogen atom is a fluorine atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>acyl fluoride group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_505
preferred name: acyl fluoride group

imine linkage between primary amine and aldehyde
type: Class
subclass of: imine linkage
subclass of: Restriction
  on property: derives from
  some values from: aldehyde group
subclass of: Restriction
  on property: derives from
  some values from: primary amine group
subclass of: Restriction
  on property: part of
  some values from: imine group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imine linkage which is formed between a primary amine and an aldehyde, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>imine linkage between primary amine and aldehyde</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_507
preferred name: imine linkage between primary amine and aldehyde

tertiary amine group
type: Class
subclass of: amine group
subclass of: Restriction
  on property: part of
  some values from: tertiary amine
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amine group which is formally derived by the removal of three hydrogen atoms from ammonia, by virtue of which it has the structure -N(-)-. The group is characteristic of a tertiary amine molecule wherein it is attached to hydrocarbyl groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tertiary amine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_508
preferred name: tertiary amine group

anticancer drug directed against endothelium
type: Class
subclass of: anticancer drug based on target
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that is directed to affect the tumor endothelial cells.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>anticancer drug directed against endothelium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_509
preferred name: anticancer drug directed against endothelium

alpha V beta inhibitor
type: Class
subclass of: endothelial-specific integrin inhibitor
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An endothelial-specific integrin inhibitor that acts by blocking the action of an endothelial cell-surface expressed alpha (v) integrin, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>alpha V beta inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C2050
code: NPO_510
preferred name: alpha V beta inhibitor

acyl compound
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: acyl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acyl compound is an organic compound which is characterized by the presence of an acyl group R-C(=O)-, where R denotes an organic group and the carbon atom is not bonded to a hydrogen atom or oxygen atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>acyl compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_511
preferred name: acyl compound

curium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 96
subclass of: Restriction
  on property: is integral part of
  all values from: curium
subclass of: Restriction
  on property: is integral part of
  some values from: curium
disjoint with: polonium atom
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 96.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>curium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_513
preferred name: curium atom

soluble in water
type: Class
subclass of: solubility in water
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A qualitative measure of solubility in water which indicates that the chemical substance dissolves in water under specific conditions.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>soluble in water</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_514
preferred name: soluble in water
synonym: water-soluble

conical shape
type: Class
subclass of: shape
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shape formed by the surface of a 3-dimensional object that tapers from a circular base.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>conical shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_515
synonym: conical
preferred name: conical shape

europium
type: Class
subclass of: element
disjoint with: gold
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 63.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>europium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_516
preferred name: europium

gold
type: Class
subclass of: element
disjoint with: hydrogen
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 79.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gold</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
symbol: Au
code: NPO_518
preferred name: gold

isocyanate compound
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: isocyanate group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An isocyanate is an organic compound characterized by the presence of isocyanate group. It has the structure R-N=C=O, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>isocyanate compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_519
preferred name: isocyanate compound

hydrogen
type: Class
subclass of: element
disjoint with: antimony
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 1.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydrogen</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_520
preferred name: hydrogen

polonium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: polonium
subclass of: Restriction
  on property: atomic Number
  has value: 84
subclass of: Restriction
  on property: is integral part of
  all values from: polonium
disjoint with: iridium atom
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 84.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>polonium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_521
preferred name: polonium atom

antimony
type: Class
subclass of: element
disjoint with: niobium
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 51.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>antimony</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_522
preferred name: antimony

drug directed against extracellular domain of membrane receptor
type: Class
subclass of: drug directed against membrane receptor
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that blocks the extracellular domain of the membrane receptor.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>drug directed against extracellular domain of membrane receptor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_523
preferred name: drug directed against extracellular domain of membrane receptor

shell of nanocapsule
type: Class
subclass of: shell
subclass of: Restriction
  on property: part of
  all values from: Nanocapsule
subclass of: Restriction
  on property: part of
  some values from: Nanocapsule
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The shell of a nanocapsule.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>shell of nanocapsule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_524
preferred name: shell of nanocapsule

iridium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: iridium
subclass of: Restriction
  on property: atomic Number
  has value: 77
subclass of: Restriction
  on property: is integral part of
  all values from: iridium
disjoint with: radon atom
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 77.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>iridium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_525
preferred name: iridium atom

imine linkage
type: Class
subclass of: covalent linkage
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an imine group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>imine linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_526
preferred name: imine linkage

nanoparticle response to pH change
type: Class
subclass of: nanoparticle response to internal stimulus
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to internal stimulus, which occurs in response to a change in pH.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanoparticle response to pH change</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_528
preferred name: nanoparticle response to pH change

transition element
type: Class
equivalent class: Class
  union of: Group 5 Element
  union of: Group 6 Element
  union of: Group 4 Element
  union of: Group 10 Element
  union of: Group 9 Element
  union of: Group 8 Element
  union of: Group 12 Element
  union of: yttrium
  union of: Group 11 Element
  union of: scandium
  union of: Group 7 Element
subclass of: d-block element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A metal which is any of the following elements: d-block element or one of the elements in groups 4, 5, 6, 10, 11, 12.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>transition element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_529
preferred name: transition element

maleimide derivative
type: Class
subclass of: imide
subclass of: Restriction
  on property: has part
  some values from: maleimide group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A maleimide derivative is an imide derived from maleimide by replacing the hydrogen atom bonded to nitrogen in maleimide by an organic group. It is characterized by the presence of a maleimide group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>maleimide derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_530
preferred name: maleimide derivative

radon atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: radon
subclass of: Restriction
  on property: atomic Number
  has value: 86
subclass of: Restriction
  on property: is integral part of
  some values from: radon
disjoint with: roentgenium atom
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 86.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>radon atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_531
preferred name: radon atom

suspension
type: Class
equivalent class: Class
  intersection of: mixture
  intersection of: Restriction
    on property: has quality
    some values from: state of suspension
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A mixture in which fine particles are suspended in a fluid where they are supported by buoyancy.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>WordNet</ncicp:attr><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>suspension</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C45304
code: NPO_532
preferred name: suspension

roentgenium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: roentgenium
subclass of: Restriction
  on property: is integral part of
  some values from: roentgenium
subclass of: Restriction
  on property: atomic Number
  has value: 111
disjoint with: astatine atom
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 111.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>roentgenium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_533
preferred name: roentgenium atom

astatine atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: astatine
subclass of: Restriction
  on property: atomic Number
  has value: 85
subclass of: Restriction
  on property: is integral part of
  all values from: astatine
disjoint with: selenium atom
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 85.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>astatine atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_534
preferred name: astatine atom

selenium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: selenium
subclass of: Restriction
  on property: atomic Number
  has value: 34
subclass of: Restriction
  on property: is integral part of
  some values from: selenium
disjoint with: dysprosium atom
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 34.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>selenium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_535
preferred name: selenium atom

imine group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: imine
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=N-)-. The group is the characteristic of an imine.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>imine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_536
preferred name: imine group

carbohydrate-coated nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: Class
      intersection of: carbohydrate
      intersection of: Restriction
        on property: has role
        some values from: nanoparticle surface modifying role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a coating agent composed of a carbohydrate.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carbohydrate-coated nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_537
preferred name: carbohydrate-coated nanoparticle

dysprosium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: dysprosium
subclass of: Restriction
  on property: is integral part of
  all values from: dysprosium
subclass of: Restriction
  on property: atomic Number
  has value: 66
disjoint with: silicon atom
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 66.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dysprosium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_538
preferred name: dysprosium atom

silicon atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: silicon
subclass of: Restriction
  on property: is integral part of
  some values from: silicon
subclass of: Restriction
  on property: atomic Number
  has value: 14
disjoint with: fermium atom
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 14.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>silicon atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_541
preferred name: silicon atom

targeting role
type: Class
subclass of: agent role
subclass of: Restriction
  on property: role of
  some values from: targeting agent
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Role played by a molecular entity that is used to target a material entity, and the role is realized during the process of molecular targeting.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>targeting role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_542
preferred name: targeting role

large unilamellar vesicle
type: Class
subclass of: unilamellar vesicle
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unilamellar vesicle, which has size greater than 100 nm.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>large unilamellar vesicle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_543
preferred name: large unilamellar vesicle

imidoester group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: imidoester compound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure C(=[NH2+])-O-CH3. The group is characteristic of an imidoester compound.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>imidoester group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_544
preferred name: imidoester group

anticancer drug directed against tumor cell
type: Class
subclass of: anticancer drug based on target
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug directed against a tumor cell to affect its division and function.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>anticancer drug directed against tumor cell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_549
preferred name: anticancer drug directed against tumor cell

gold quantum dot-entrapped poly(amidoamine) dendrimer nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: poly(amidoamine) dendrimer
  intersection of: Restriction
    on property: has entrapped component part
    some values from: gold quantum dot
  intersection of: Restriction
    on property: has part
    some values from: entrapment
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of poly(amidoamine) dendrimer in which gold quantum dots are entrapped.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gold quantum dot-entrapped poly(amidoamine) dendrimer nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_551
preferred name: gold quantum dot-entrapped poly(amidoamine) dendrimer nanoparticle

antibody
type: Class
subclass of: protein
subclass of: Restriction
  on property: has function
  all values from: Class
    intersection of: binding function
    intersection of: Restriction
      on property: is realized in
      some values from: antigen binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of protein made by B lymphocytes in response to a foreign substance (antigen). Each antibody only binds to a specific antigen, helping to destroy the antigen directly or by assisting white blood cells to destroy the antigen.[source: NCI_Thesaurus]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>antibody</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: MESH:D000906
DB xref ID: NCIT: C16295
code: NPO_552
preferred name: antibody

diamagnetic
type: Class
subclass of: magnetic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Magnetic property exhibited in materials which create a weak magnetic field in opposition to an externally applied magnetic field; thus, causing repulsion of the material in a magnetic field.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>diamagnetic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_553
preferred name: diamagnetic

fermium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: fermium
subclass of: Restriction
  on property: atomic Number
  has value: 100
subclass of: Restriction
  on property: is integral part of
  all values from: fermium
disjoint with: indium atom
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 100.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fermium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_554
preferred name: fermium atom

block element
type: Class
equivalent class: Class
  union of: d-block element
  union of: g-block element
  union of: f-block element
  union of: s-block element
  union of: p-block element
subclass of: periodic table element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electrons occupy some orbital.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>block element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_555
preferred name: block element

taxane-pocket binding agent
type: Class
equivalent class: Class
  intersection of: tubulin binding agent
  intersection of: Restriction
    on property: has function
    some values from: Class
      intersection of: binding function
      intersection of: Restriction
        on property: is realized in
        some values from: beta-tubulin binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Tubulin binding agent that binds to the taxane site of the beta-tubulin subunit, a region described as a binding pocket located within the middle domain and corresponding to an approximate residue sequence of 217-231. Specifically, these agents bind to a cysteine residue within the pocket, which is also the binding site for GTP. Agents binding at the taxane site promote the polymerization of dimers to form a very rigid and stable microtubule structure which is not readily disassembled. Interfering with microtubule dynamics, these agents inhibit the normal turnover process essential during mitosis, thereby causing cell-cycle arrest and/or apoptosis. [source: NCIT]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>taxane-pocket binding agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C67437
code: NPO_556
preferred name: taxane-pocket binding agent

indium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: indium
subclass of: Restriction
  on property: is integral part of
  all values from: indium
subclass of: Restriction
  on property: atomic Number
  has value: 49
disjoint with: platinum atom
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 49.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>indium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_557
preferred name: indium atom

niobium
type: Class
subclass of: element
disjoint with: iron
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 41.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>niobium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_558
preferred name: niobium

thiocyanate compound
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: thiocyanate group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thioyanate compound is an organic compound which is characterized by the presence of a thiocyanate group. It has the structure R-S-C#N, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thiocyanate compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_560
synonym: thiocyanate
preferred name: thiocyanate compound

platinum atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: platinum
subclass of: Restriction
  on property: is integral part of
  some values from: platinum
subclass of: Restriction
  on property: atomic Number
  has value: 78
disjoint with: vanadium atom
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 78.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>platinum atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_561
preferred name: platinum atom

anticancer drug directed against endothelial growth factor receptor
type: Class
subclass of: anticancer drug directed against endothelium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that is directed to affect the synthesis and function of a receptor of an endothelial growth factor.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>anticancer drug directed against endothelial growth factor receptor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_562
preferred name: anticancer drug directed against endothelial growth factor receptor

covalent linkage
type: Class
subclass of: attachment
subclass of: Restriction
  on property: bearer of
  some values from: covalent interaction
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An attachment formed via covalent bonding between chemical groups of molecular entities.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>covalent linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_563
synonym: covalent attachment
synonym: covalent conjugation
preferred name: covalent linkage

antineoplastic activity
type: Class
subclass of: process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process that prevents or inhibits the maturation ,growth or spread of tumor cells.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>antineoplastic activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_564
preferred name: antineoplastic activity

nanoparticle response to stimulus
type: Class
subclass of: process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process, which describes the function or activity of a nanoparticle, occurring in response to a stimulus acting on the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanoparticle response to stimulus</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_565
preferred name: nanoparticle response to stimulus

ionizable to gain positive charge
type: Class
subclass of: ionizable
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ionizable property inhering in a chemical substance by virtue of having the ability to be ionized and gain a positive charge.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ionizable to gain positive charge</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_566
preferred name: ionizable to gain positive charge

tyrosine kinase inhibitor
type: Class
equivalent class: Class
  intersection of: protein kinase inhibitor
  intersection of: Restriction
    on property: has role
    some values from: Class
      intersection of: inhibitor role
      intersection of: Restriction
        on property: is realized in
        some values from: inhibition of protein tyrosine kinase activity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A protein kinase inhibitor, which inhibits tyrosine kinase enzyme, involved with the transduction and processing of many extracellular and intracellular signals including cell proliferation.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tyrosine kinase inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C1967
code: NPO_567
preferred name: tyrosine kinase inhibitor

iron
type: Class
subclass of: element
disjoint with: roentgenium
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 26.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>iron</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_568
preferred name: iron

roentgenium
type: Class
subclass of: element
disjoint with: praseodymium
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 111.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>roentgenium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_570
preferred name: roentgenium

vanadium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: vanadium
subclass of: Restriction
  on property: is integral part of
  all values from: vanadium
subclass of: Restriction
  on property: atomic Number
  has value: 23
disjoint with: lutetium atom
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 23.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>vanadium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_571
preferred name: vanadium atom

drug directed against tumor RNA
type: Class
subclass of: anticancer drug directed against tumor cell
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Anticancer drug which is directed to interfere with the synthesis, function or activity of mRNA.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>drug directed against tumor RNA</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_572
preferred name: drug directed against tumor RNA

inhibitor role
type: Class
subclass of: regulator role
subclass of: Restriction
  on property: is realized in
  some values from: inhibition
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Role borne by a molecular entity which prevents or slows down an activity or process; or that reduces the activity of another molecular entity.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>inhibitor role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_576
preferred name: inhibitor role

cetuximab
type: Class
subclass of: monoclonal antibody
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: binding function
    intersection of: Restriction
      on property: is realized in
      some values from: epidermal growth factor receptor binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A recombinant, chimeric monoclonal antibody directed against the epidermal growth factor receptor (EGFR) with antineoplastic activity. Cetuximab binds to the extracellular domain of the EGFR, thereby preventing the activation and subsequent dimerization of the receptor; the decrease in receptor activation and dimerization may result in an inhibition in signal transduction and anti-proliferative effects. This agent may inhibit EGFR-dependent primary tumor growth and metastasis. EGFR is overexpressed on the cell surfaces of various solid tumors.[source: NCI_Thesaurus]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cetuximab</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: Erbitux
DB xref ID: NCIT:C1723
code: NPO_577
preferred name: cetuximab
comment: drug directed against extracellular domain of membrane receptor

praseodymium
type: Class
subclass of: element
disjoint with: hassium
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 59.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>praseodymium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_579
preferred name: praseodymium

imine linkage between secondary amine and aldehyde
type: Class
subclass of: imine linkage
subclass of: Restriction
  on property: derives from
  some values from: aldehyde group
subclass of: Restriction
  on property: part of
  some values from: imine group
subclass of: Restriction
  on property: derives from
  some values from: secondary amine group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imine linkage which is formed between a secondary amine and an aldehyde, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>imine linkage between secondary amine and aldehyde</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_580
preferred name: imine linkage between secondary amine and aldehyde

dipole-dipole interaction
type: Class
subclass of: intermolecular interaction
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An intermolecular interaction between molecules (polar or non-polar) due to attraction between permanent or temporary molecular dipoles.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dipole-dipole interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_582
synonym: Van Der Waals Interaction
preferred name: dipole-dipole interaction

polypeptide chain
type: Class
subclass of: polypeptide
subclass of: Restriction
  on property: part of
  some values from: protein
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polypeptide, which is part of some protein molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>polypeptide chain</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_585
preferred name: polypeptide chain

hassium
type: Class
subclass of: element
disjoint with: oxygen
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 108.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hassium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_586
preferred name: hassium

lutetium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 71
subclass of: Restriction
  on property: is integral part of
  all values from: lutetium
subclass of: Restriction
  on property: is integral part of
  some values from: lutetium
disjoint with: gold atom
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 71.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>lutetium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_587
preferred name: lutetium atom

quantum dot
type: Class
subclass of: three-dimensional nanoparticle
subclass of: Restriction
  on property: has quality
  some values from: spherical shape
comment: (NCI_Thesaurus definition): Nanometer-sized semiconductor particles, made of cadmium selenide (CdSe), cadmium sulfide (CdS) or cadmium telluride (CdTe) with an inert polymer coating. The semiconductor material used for the core is chosen based upon the emission wavelength range being targeted: CdS for UV-blue, CdSe for the bulk of the visible spectrum, and CdTe for far red and near-infrared. The size of the particle determines the exact color of a given quantum dot. The polymer coating protects cells from cadmium toxicity but also facilitates the attachment of a variety of targeting molecules, including monoclonal antibodies directed to tumor-specific biomarkers. Because of their small size, quantum dots can function as cell- and even molecule-specific markers that will not interfere with the normal cellular functions.
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A three-dimensional nanoparticle which is made of material that exhibits quantum effects.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>quantum dot</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_589
synonym: QD
preferred name: quantum dot

gold atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 79
subclass of: Restriction
  on property: is integral part of
  all values from: gold
subclass of: Restriction
  on property: is integral part of
  some values from: gold
disjoint with: terbium atom
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 79.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gold atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_591
preferred name: gold atom

terbium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: terbium
subclass of: Restriction
  on property: is integral part of
  all values from: terbium
subclass of: Restriction
  on property: atomic Number
  has value: 65
disjoint with: rhenium atom
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 65.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>terbium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_592
preferred name: terbium atom

DNA synthesis inhibitor
type: Class
equivalent class: Class
  intersection of: antineoplastic agent
  intersection of: Restriction
    on property: has role
    some values from: Class
      intersection of: inhibitor role
      intersection of: Restriction
        on property: is realized in
        some values from: negative regulation of DNA replication
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antineoplastic agent, which inhibits the synthesis of DNA.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>DNA synthesis inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: DNA synthesis inhibitor
code: NPO_594

photosensitizing agent
type: Class
equivalent class: Class
  intersection of: antineoplastic agent
  intersection of: Restriction
    on property: has property
    some values from: photosensitive
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anticancer drug that is pharmacologically inactive but when exposed to ultraviolet light or sunlight, it is converted to its pharmacologically active metabolite.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>photosensitizing agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: MESH: D017319
DB xref ID: NCIT: C1420
code: NPO_596
synonym: photosensitizer
preferred name: photosensitizing agent

mitroxantrone
type: Class
subclass of: organic compound or molecule
subclass of: Restriction
  on property: has role
  some values from: anticancer drug role
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: therapeutic function
    intersection of: Restriction
      on property: is realized in
      some values from: antineoplastic activity
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: inhibitor role
    intersection of: Restriction
      on property: is realized in
      some values from: inhibition of DNA topoisomerase type II activity
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: antibiotic role
    intersection of: Restriction
      on property: is realized in
      some values from: inhibition of cancer cell growth
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound which functions as a topoisomerase-II inhibitor and an antineoplastic antibiotic.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>mitroxantrone</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C62050
code: NPO_597
comment: anticancer drug that inhibits protein activity related to DNA synthesis
preferred name: mitroxantrone

insoluble in water
type: Class
subclass of: solubility in water
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A qualitative measure of "solubility in water" which indicates the poor ability of the chemical substance to dissolve in water under specific conditions.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>insoluble in water</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_598
preferred name: insoluble in water
synonym: water-insoluble

labeling role
type: Class
subclass of: molecular role
subclass of: Restriction
  on property: role of
  some values from: labeling molecule
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Role played by a material entity when it is used for labeling another material entity.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>labeling role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_599
preferred name: labeling role

gel
type: Class
equivalent class: Class
  intersection of: colloid
  intersection of: Restriction
    on property: has quality
    some values from: gel state
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A colloid, which is a semi-solid or jelly like material formed by the coagulation of a colloidal liquid.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gel</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_601
preferred name: gel

carbon nanofiber
type: Class
equivalent class: Class
  intersection of: nanofiber
  intersection of: Restriction
    on property: has part
    some values from: carbon
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanofiber which is composed of graphene layers arranged as stacked cones, cups or plates. Carbon nanofibers with graphene layers wrapped into perfect cylinders are called carbon nanotubes.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carbon nanofiber</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_602
preferred name: carbon nanofiber

rhenium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: rhenium
subclass of: Restriction
  on property: atomic Number
  has value: 75
subclass of: Restriction
  on property: is integral part of
  some values from: rhenium
disjoint with: germanium atom
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 75.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>rhenium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_604
preferred name: rhenium atom

tumor targeting
type: Class
subclass of: targeting
subclass of: Restriction
  on property: has participant
  some values from: Class
    intersection of: tumor
    intersection of: Restriction
      on property: has role
      some values from: target role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The process of directing a molecule or a particle to a specific location in a tumor.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tumor targeting</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_605
preferred name: tumor targeting

carbon nanotube
type: Class
equivalent class: Class
  intersection of: nanotube
  intersection of: Restriction
    on property: has part
    some values from: carbon
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanotube which consists of one or more graphite sheets (graphene) of hexagonal arrays of carbon rolled into seamless cylinders with capped ends.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carbon nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_606
preferred name: carbon nanotube

germanium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: germanium
subclass of: Restriction
  on property: is integral part of
  all values from: germanium
subclass of: Restriction
  on property: atomic Number
  has value: 32
disjoint with: argon atom
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 32.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>germanium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_609
preferred name: germanium atom

argon atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: argon
subclass of: Restriction
  on property: atomic Number
  has value: 18
subclass of: Restriction
  on property: is integral part of
  all values from: argon
disjoint with: lead atom
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 18.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>argon atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_610
preferred name: argon atom

Group 10 Element
type: Class
equivalent class: Class
  union of: palladium
  union of: darmstadtium
  union of: platinum
  union of: nickel
subclass of: group element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 10 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Group 10 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Group 10 Element
code: NPO_611
synonym: nickel group element

hollow core of nanocage
type: Class
subclass of: core site
subclass of: Restriction
  on property: part of
  some values from: nanocage
disjoint with: hydrophobic core of micelle
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The hollow core region of a nanocage.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hollow core of nanocage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_612
preferred name: hollow core of nanocage

lead atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 51
subclass of: Restriction
  on property: is integral part of
  all values from: lead
subclass of: Restriction
  on property: is integral part of
  some values from: lead
disjoint with: hassium atom
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 51.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>lead atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_613
preferred name: lead atom

ketone group
type: Class
subclass of: carbonyl group
subclass of: Restriction
  on property: part of
  some values from: ketone
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carbonyl group which is characteristic of a ketone wherein it is attached to two carbon atoms via covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ketone group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_614
preferred name: ketone group

oxygen
type: Class
subclass of: element
disjoint with: radium
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 8.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>oxygen</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_615
preferred name: oxygen

endothelial-specific integrin inhibitor
type: Class
subclass of: angiogenesis inhibitor
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An angiogenesis inhibitor that acts by blocking the action of endothelial integrins. An endothelial-specific integrin/survival signaling inhibitor binds to and blocks the activity of endothelial-specific integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>endothelial-specific integrin inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C2144
code: NPO_616
comment: [definition source]: NCI_Thesaurus
preferred name: endothelial-specific integrin inhibitor
synonym: survival signaling inhibitor

nanoparticle response to internal stimulus
type: Class
subclass of: nanoparticle response to stimulus
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to stimulus, which occurs in response to the internal stimulus acting on the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanoparticle response to internal stimulus</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_617
preferred name: nanoparticle response to internal stimulus

paclitaxel-loaded nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: Class
      intersection of: paclitaxel
      intersection of: Restriction
        on property: has role
        some values from: payload agent role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is loaded with paclitaxel.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>paclitaxel-loaded nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_618
preferred name: paclitaxel-loaded nanoparticle

nanocage
type: Class
subclass of: three-dimensional nanoparticle
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A three-dimensional nanoparticle with a hollow core and a porous wall or shell. It's structure resembles that of a hollow cage, that is similar to a fullerene type of nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanocage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_619
preferred name: nanocage

DNA crosslinking agent
type: Class
equivalent class: Class
  intersection of: DNA binding agent
  intersection of: Restriction
    on property: has role
    some values from: Class
      intersection of: agent role
      intersection of: Restriction
        on property: is realized in
        some values from: DNA crosslinking
subclass of: Restriction
  on property: agent in
  some values from: DNA crosslinking
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>DNA binding agent that is able to covalently bind to DNA causing inter- or intra-stranded cross-linking of DNA. The cross-linking results in misreading of the DNA code and inhibition of DNA synthesis.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>DNA crosslinking agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: DNA crosslinking agent
DB xref ID: NCIT:C25760
code: NPO_620

dendrimer repeat unit
type: Class
subclass of: repeat unit
subclass of: Restriction
  on property: part of
  some values from: dendrimer branch
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecule component in dendrimer which repeats to form the branches of a dendrimer.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dendrimer repeat unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_621
preferred name: dendrimer repeat unit

hassium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: hassium
subclass of: Restriction
  on property: atomic Number
  has value: 108
subclass of: Restriction
  on property: is integral part of
  some values from: hassium
disjoint with: nitrogen atom
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 108.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hassium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_622
preferred name: hassium atom

nitrogen atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 7
subclass of: Restriction
  on property: is integral part of
  some values from: nitrogen
subclass of: Restriction
  on property: is integral part of
  all values from: nitrogen
disjoint with: einsteinium atom
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 7.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nitrogen atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_623
preferred name: nitrogen atom

Group 2 Element
type: Class
equivalent class: Class
  union of: strontium
  union of: beryllium
  union of: magnesium
  union of: calcium
  union of: barium
  union of: radium
subclass of: group element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 2 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Group 2 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Group 2 Element
code: NPO_625

amide linkage
type: Class
subclass of: covalent linkage
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an amide group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>amide linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_626
synonym: amide bond
preferred name: amide linkage

acoustic-sensitive
type: Class
subclass of: sensitivity to stimulus
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition, inhering in any material entity, whose structure or function can be altered by sound.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>acoustic-sensitive</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_627
preferred name: acoustic-sensitive

ionizability
type: Class
subclass of: realizable_entity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity that inheres in a molecular entity or group, and that describes the ability of the bearer to be ionized.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ionizability</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_628
preferred name: ionizability

Group 9 Element
type: Class
equivalent class: Class
  union of: iridium
  union of: rhodium
  union of: meitnerium
  union of: cobalt
subclass of: group element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 9 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Group 9 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Group 9 Element
code: NPO_630
synonym: cobalt group element

solid lipid nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: lipid
  intersection of: Restriction
    on property: has quality
    some values from: solid state
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle whuch is basically composed of solidified lipid molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>solid lipid nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_631
preferred name: solid lipid nanoparticle

anticancer drug based on target
type: Class
subclass of: anticancer drug
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Anticancer drug, which is the role of a molecular entity, realized from the kind of biological target where the molecular entity is primarily intended or directed to act.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>anticancer drug based on target</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_633
comment: [classification source]: E. Espinosa, P. Zamora, J. Feliu and M. G. Baron, Classification of anticancer drugs-a new system based on therapeutic targets, Cancer Treatment Reviews, 29: 515-523 (2003).
preferred name: anticancer drug based on target

ferromagnetic
type: Class
subclass of: magnetic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Magnetic property exhibited by materials in presence of an external magnetic field and the magnetism is retained for a period even after the magnetic field is removed (magnetic moments of the adjacent atoms are aligned in the same direction at temperatures below the Curie temperature).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ferromagnetic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_634
preferred name: ferromagnetic

payload agent role
type: Class
subclass of: component role in nanoparticle
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecule role in nanoparticle, which inheres in a molecular entity that has active end-directed functions/activities and is transported and delivered by the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>payload agent role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_635
preferred name: payload agent role

nanosphere
type: Class
equivalent class: Class
  intersection of: three-dimensional nanoparticle
  intersection of: Restriction
    on property: has quality
    some values from: spherical shape
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A three-dimensional nanoparticle which is spherical, porous or non-porous and its diameter is measured in nanometers.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanosphere</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_636
preferred name: nanosphere

amidine linkage between primary amine and imidoester
type: Class
subclass of: amidine linkage
subclass of: Restriction
  on property: derives from
  some values from: primary amine group
subclass of: Restriction
  on property: part of
  some values from: carboxamidine group
subclass of: Restriction
  on property: derives from
  some values from: imidoester group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amidine linkage which occurs between a primary amine and an imidoester, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>amidine linkage between primary amine and imidoester</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_637
preferred name: amidine linkage between primary amine and imidoester

sensitivity to stimulus
type: Class
subclass of: disposition
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition, inhering in any material entity, whose structure or function can be altered by a stimulus.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>sensitivity to stimulus</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_638
preferred name: sensitivity to stimulus

emulsion
type: Class
equivalent class: Class
  intersection of: colloid
  intersection of: Restriction
    on property: has quality
    some values from: state of emulsion
subclass of: Restriction
  on property: has part
  some values from: emulsifier
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: compound or molecule
    intersection of: Restriction
      on property: has role
      some values from: emulsifying role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A colloid in which both phases are liquids that are immiscible with each other.[source: WordNet 3.0]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>emulsion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C63807
code: NPO_639
comment: [source]: http://www.thefreedictionary.com
preferred name: emulsion

imide
type: Class
equivalent class: Class
  intersection of: amide
  intersection of: Restriction
    on property: has part
    some values from: imide group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imide is an amide which is characterized by the presence of an imide group. It has the structure R-C(=O)-N(-R')-C(=O)-R", where R, R" denote organic groups, and R' stands for organic group or hydrogen atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>imide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_640
preferred name: imide

material site
type: Class
subclass of: independent_continuant
subclass of: Restriction
  on property: has quality
  some values from: hollow
subclass of: Restriction
  on property: part of
  some values from: material entity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An independent continuant [snap:IndependentContinuant] consisting of a characteristic spatial shape in relation to some arrangement of material entities and of the medium which is enclosed in whole or in part by this characteristic spatial shape. Material site entities are entities that can be occupied by other material entities.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>material site</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
editor note: A foreign molecule could be covalently linked to a molecular constituent or it could occupy a void space / cavity by participating in non-covalent interactions iwth neighboring molecular constituents.
code: NPO_641
editor note: [previous definition]: An independent continuant which describes any distinguishable point, site or location in a material entity, and the location is either that of a group of molecular constituents in a material entity, or the space surrounded by the molecular constituents.
comment: definition of material site is based on the definition of snap:Site
preferred name: material site

dendrimer cavity
type: Class
subclass of: material site
subclass of: Restriction
  on property: part of
  some values from: Class
    union of: dendrimer generation layer
    union of: dendrimer core
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A material site which is a cavity or space formed within the core and generation layer (between branches) of a dendrimer. It can be occupied by molecules other than those which chemically make up the dendrimer.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dendrimer cavity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_642
preferred name: dendrimer cavity

fluorochrome
type: Class
equivalent class: Class
  intersection of: fluorescent dye
  intersection of: Restriction
    on property: has application
    some values from: Class
      union of: fluorescence microscopy
      union of: fluorescence spectroscopy
      union of: fluorescence imaging
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fluorescent dye which is used to stain a specimen or a sample in fluorescence microscopy.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fluorochrome</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C503
code: NPO_643
preferred name: fluorochrome

thioether linkage between thiol and iodoacetyl derivative
type: Class
subclass of: thioether linkage
subclass of: Restriction
  on property: derives from
  some values from: sulfhydryl group
subclass of: Restriction
  on property: derives from
  some values from: iodoacetyl group
subclass of: Restriction
  on property: part of
  some values from: thioether group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thioether linkage which occurs between a thiol and an iodoacetyl derivative, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thioether linkage between thiol and iodoacetyl derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_644
preferred name: thioether linkage between thiol and iodoacetyl derivative

topotecan
type: Class
subclass of: organic compound or molecule
subclass of: Restriction
  on property: has role
  some values from: anticancer drug role
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: therapeutic function
    intersection of: Restriction
      on property: is realized in
      some values from: antineoplastic activity
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: inhibitor role
    intersection of: Restriction
      on property: is realized in
      some values from: inhibition of DNA topoisomerase type I activity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A semisynthetic derivative of camptothecin, a cytotoxic, quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>topotecan</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_645
preferred name: topotecan

halogen atom
type: Class
equivalent class: Class
  union of: iodine atom
  union of: fluorine atom
  union of: chlorine atom
  union of: astatine atom
  union of: bromine atom
subclass of: atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom of fluorine or chlorine or bromine or iodine or astatine.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>halogen atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_646
preferred name: halogen atom

arylthioether linkage
type: Class
subclass of: covalent linkage
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an arylthioether group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>arylthioether linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_648
preferred name: arylthioether linkage

heterobifunctional crosslinker
type: Class
subclass of: crosslinking reagent
subclass of: Restriction
  on property: has part
  some values from: spacer
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A crosslinking agent which contains two different end reactive groups connected by a spacer, and the two reactive groups can couple to two different functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>heterobifunctional crosslinker</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_649
preferred name: heterobifunctional crosslinker

succinimidyl carbonate compound
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: succinimidyl carbonate group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound which is characterized by the presence of a succinimidyl carbonate group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>succinimidyl carbonate compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_650
preferred name: succinimidyl carbonate compound

radium
type: Class
subclass of: element
disjoint with: thorium
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 88.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>radium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_651
preferred name: radium

thorium
type: Class
subclass of: element
disjoint with: astatine
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 90.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thorium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_652
preferred name: thorium

stimulus of pH change
type: Class
subclass of: internal stimulus for nanoparticle function
subclass of: Restriction
  on property: stimulus causes response
  some values from: nanoparticle response to pH change
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An internal stimulus for nanoparticle function, which is caused by a change in pH of the medium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>stimulus of pH change</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_653
preferred name: stimulus of pH change

einsteinium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: einsteinium
subclass of: Restriction
  on property: atomic Number
  has value: 99
subclass of: Restriction
  on property: is integral part of
  some values from: einsteinium
disjoint with: sufur atom
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 99.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>einsteinium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_654
preferred name: einsteinium atom

intermolecular interaction
type: Class
subclass of: non-covalent interaction
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An attractive non-covalent interaction between two or more (otherwise non-associated) molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>intermolecular interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_655
preferred name: intermolecular interaction

Period 5 Element
type: Class
equivalent class: Class
  union of: strontium
  union of: rhodium
  union of: iodine
  union of: rubidium
  union of: indium
  union of: palladium
  union of: antimony
  union of: niobium
  union of: tellurium
  union of: technetium
  union of: silver
  union of: yttrium
  union of: tin
  union of: xenon
  union of: zirconium
  union of: ruthenium
  union of: molybdenum
  union of: cadmium
subclass of: period element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element in the fifth row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Period 5 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_656
preferred name: Period 5 Element

sufur atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 16
subclass of: Restriction
  on property: is integral part of
  some values from: sulfur
subclass of: Restriction
  on property: is integral part of
  all values from: sulfur
disjoint with: technetium atom
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 16.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>sufur atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_658
preferred name: sufur atom

noble gas
type: Class
equivalent class: Class
  union of: radon
  union of: neon
  union of: xenon
  union of: argon
  union of: helium
  union of: krypton
subclass of: non-metal
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A non-metal which is any of the following elements: argon, helium, krypton, neon, radon, xenon.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>noble gas</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_660
synonym: inert element
preferred name: noble gas

core-shell nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has part
    some values from: core
  intersection of: Restriction
    on property: has part
    some values from: shell
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a core part and a shell part, and both the core and shell are distinguished by their respective material content.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>core-shell nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_661
preferred name: core-shell nanoparticle

drug release from nanoparticle in response to magnetic field
type: Class
subclass of: nanoparticle response to magnetic field
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to magnetic field, which involves the release of drugs from a drug-loaded nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>drug release from nanoparticle in response to magnetic field</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_662
preferred name: drug release from nanoparticle in response to magnetic field

astatine
type: Class
subclass of: element
disjoint with: tellurium
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 85.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>astatine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_663
preferred name: astatine

Group 8 Element
type: Class
equivalent class: Class
  union of: iron
  union of: hassium
  union of: osmium
  union of: ruthenium
subclass of: group element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 8 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Group 8 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Group 8 Element
code: NPO_664
synonym: iron group element

nanocantilever
type: Class
subclass of: nanodevice
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as the simplest micro-electro-mechanical system (MEMS) that is easily machined and mass-produced for probing nanoscale specimens.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanocantilever</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_665
comment: Nanocantilevers are often used to explore and characterize the surfaces of biological systems. The motion of the device is recorded and transformed mathematically to provide information about these surface characteristics.
preferred name: nanocantilever

hexahedral shape
type: Class
subclass of: polyhedral shape
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A polyhedral shape that inheres in a 3-dimensional object having six plane faces.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>hexahedral shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_666
comment: [source]: WordNet
synonym: hexahedral
preferred name: hexahedral shape

one-dimensional nanoparticle
type: Class
subclass of: nanoparticle
synonym: 1-D nanoparticle
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has only one external dimension in the nanoscale size range.</ncicp:def-definition><ncicp:Definition_Review_Date>110104</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>one-dimensional nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_667
preferred name: one-dimensional nanoparticle

tellurium
type: Class
subclass of: element
disjoint with: arsenic
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 52.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tellurium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_668
preferred name: tellurium

inorganic
type: Class
subclass of: independent specific individual quality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality that inheres in a molecular entity which does not contain carbon as a principal element (some exceptions exist, e.g., carbon dioxide).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>inorganic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C66829
code: NPO_669
preferred name: inorganic

liquid
type: Class
equivalent class: Class
  intersection of: fluid
  intersection of: Restriction
    on property: has quality
    some values from: liquid state
subclass of: Restriction
  on property: has property
  some values from: refractive index
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A fluid state of matter having no fixed shape but a fixed volume.</ncicp:def-definition><ncicp:Definition_Review_Date>130524</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>liquid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C45298
code: NPO_670
preferred name: liquid

exterior surface of dendrimer
type: Class
subclass of: material boundary
subclass of: Restriction
  on property: part of
  some values from: dendrimer branch
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The exterior surface of a dendrimer formed by the dendrimer's end/surface groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>exterior surface of dendrimer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_671
preferred name: exterior surface of dendrimer

material entity
type: Class
subclass of: independent_continuant
definition: <ncicp:ComplexDefinition><ncicp:def-definition>An independent continuant [snap:IndependentContinuant] which is spatially extended and composed of matter. The identity of material entities is independent of that of other entities and can be maintained through time.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>material entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: Matter is any physical substance that has mass and occupies space.
code: NPO_672
preferred name: material entity
DB xref ID: snap:MaterialEntity

arsenic
type: Class
subclass of: element
disjoint with: platinum
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 33.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>arsenic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_673
preferred name: arsenic

Period 2 Element
type: Class
equivalent class: Class
  union of: nitrogen
  union of: beryllium
  union of: boron
  union of: fluorine
  union of: neon
  union of: oxygen
  union of: lithium
  union of: carbon
subclass of: period element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element in the second row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Period 2 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_674
preferred name: Period 2 Element

stimulus of magnetic field
type: Class
subclass of: external stimulus for nanoparticle function
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by magnetic field.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>stimulus of magnetic field</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_675
preferred name: stimulus of magnetic field

biopolymer-coated nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: Class
      intersection of: biopolymer
      intersection of: Restriction
        on property: has role
        some values from: nanoparticle surface modifying role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a coating agent composed of a biopolymer.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>biopolymer-coated nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_677
preferred name: biopolymer-coated nanoparticle

platinum
type: Class
subclass of: element
disjoint with: bismuth
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 78.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>platinum</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_678
preferred name: platinum

technetium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 43
subclass of: Restriction
  on property: is integral part of
  all values from: technetium
subclass of: Restriction
  on property: is integral part of
  some values from: technetium
disjoint with: iron atom
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 43.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>technetium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_679
preferred name: technetium atom

carboxylic ester group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: carboxylic ester
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=O)-O- and it is formally derived from carboxylic acid and organic hydroxy compound. The group is characteristic of a carboxylic ester compound wherein it is attached to two carbon atoms via single covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carboxylic ester group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_682
preferred name: carboxylic ester group

polar covalent bonding
type: Class
subclass of: covalent interaction
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent bonding in which the sharing of electron pair is unequal due to difference in the electronegativities of atoms that share the electron pair.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>polar covalent bonding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_683
preferred name: polar covalent bonding

nanoprobe
type: Class
subclass of: nanodevice
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as a probing tool of nanometer-size, and combined with a nanosensor, is useful for subcellular detection of activity or phenomenon (e.g. biological phenomenon or process).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanoprobe</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C62372
code: NPO_684
preferred name: nanoprobe

targeting agent
type: Class
equivalent class: Class
  intersection of: compound for targeting
  intersection of: Restriction
    on property: has function
    some values from: targeting function
subclass of: Restriction
  on property: has role
  some values from: targeting role
subclass of: Restriction
  on property: participates in
  some values from: active targeting
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A molecule which is used for targeting other molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>targeting agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_685
preferred name: targeting agent

fullerene
type: Class
subclass of: organic compound or molecule
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fullerene refers to any cagelike, hollow molecule composed of hexagonal and/or pentagonal groups of carbon atoms , and it is regarded as the third form of carbon after diamond and graphite.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fullerene</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_686
preferred name: fullerene

carbonate ester group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: has part
  some values from: carbonyl group
subclass of: Restriction
  on property: part of
  some values from: carbonate ester
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -O-C(=O)-O-. The group is characteristic of a carbonate ester molecule wherein it is attached to two carbon atoms via single covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carbonate ester group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_687
preferred name: carbonate ester group

bismuth
type: Class
subclass of: element
disjoint with: cerium
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 83.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>bismuth</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_688
preferred name: bismuth

specific collective quality
type: Class
subclass of: collective quality
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality which inheres in a group of multiple bearers AND specific only to the type of bearers in the group.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>specific collective quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_689
preferred name: specific collective quality

iron atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: iron
subclass of: Restriction
  on property: atomic Number
  has value: 26
subclass of: Restriction
  on property: is integral part of
  all values from: iron
disjoint with: americium atom
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 26.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>iron atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_690
preferred name: iron atom

nanoarray
type: Class
subclass of: nanodevice
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as a template consisting of two-dimensional patterning of biological molecules on a surface for biological analysis.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanoarray</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C62340
code: NPO_691
preferred name: nanoarray

Group 3 Element
type: Class
equivalent class: Class
  union of: Actinide
  union of: Lanthanide
  union of: yttrium
  union of: scandium
subclass of: group element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 3 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Group 3 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Group 3 Element
code: NPO_694
synonym: scandium group element

dendrimer end group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: dendrimer
subclass of: Restriction
  on property: part of
  some values from: exterior surface of dendrimer
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular component which is a functional group that is part of a dendrimer and it is located at the surface of a dendrimer.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dendrimer end group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_695
preferred name: dendrimer end group
synonym: terminal group

amine group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: amine
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which is formally derived by the removal of one or more hydrogen atoms from ammonia, by virtue of which it has the structure -NH2 or -NH- or -N(-)-. The group is characteristic of an amine molecule wherein it is attached to hydrocarbyl groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>amine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_696
preferred name: amine group
synonym: amino group

cerium
type: Class
subclass of: element
disjoint with: potassium
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 58.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cerium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_697
preferred name: cerium

tamoxifen-loaded nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: Class
      intersection of: tamoxifen
      intersection of: Restriction
        on property: has role
        some values from: payload agent role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle loaded with tamoxifen.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tamoxifen-loaded nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_699
preferred name: tamoxifen-loaded nanoparticle

stimulus of sound
type: Class
subclass of: external stimulus for nanoparticle function
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by sound.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>stimulus of sound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_701
preferred name: stimulus of sound

Group 12 Element
type: Class
equivalent class: Class
  union of: mercury
  union of: zinc
  union of: cadmium
subclass of: group element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 12 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Group 12 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Group 12 Element
code: NPO_702
synonym: zinc group element

americium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: americium
subclass of: Restriction
  on property: is integral part of
  some values from: americium
subclass of: Restriction
  on property: atomic Number
  has value: 95
disjoint with: calcium atom
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 95.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>americium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_704
preferred name: americium atom

nanochannel
type: Class
subclass of: nanodevice
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as an in vivo implantable device, designed to deliver drugs under zero order rate kinetics at high local drug concentrations to non-resectable tumor lesions.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanochannel</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_705
comment: [definition source]: Lesinski et al, Biomedical Microdevices, vol 7, number 1, 71-79, 2005
preferred name: nanochannel

calcium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: calcium
subclass of: Restriction
  on property: atomic Number
  has value: 20
subclass of: Restriction
  on property: is integral part of
  some values from: calcium
disjoint with: actinium atom
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 20.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>calcium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_706
preferred name: calcium atom

nanoparticle
type: Class
subclass of: primary particle
subclass of: Restriction
  on property: has part
  some values from: surface of nanoparticle
subclass of: Restriction
  on property: has quality
  some values from: particle size
subclass of: Restriction
  on property: has quality
  some values from: shape
subclass of: Restriction
  on property: has quality
  some values from: particle concentration
subclass of: Restriction
  on property: has part
  some values from: Class
    union of: coat
    union of: core
    union of: shell
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A primary particle which has an average size in the nanoscale range; which has an identifiable and definite chemical composition, property or function that uniquely define the nanoparticle's type as known; and, which may or may not exhibit a size-intensive property.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: Definition is partly based on ASTM E 2456-06 (Terminology for Nanotechnology).
code: NPO_707
preferred name: nanoparticle

potassium
type: Class
subclass of: element
disjoint with: technetium
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 19.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>potassium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_708
preferred name: potassium

actinium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: actinium
subclass of: Restriction
  on property: is integral part of
  some values from: actinium
subclass of: Restriction
  on property: atomic Number
  has value: 89
disjoint with: phosphorus atom
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 89.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>actinium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_709
preferred name: actinium atom

phosphorus atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: phosphorus
subclass of: Restriction
  on property: atomic Number
  has value: 15
subclass of: Restriction
  on property: is integral part of
  all values from: phosphorus
disjoint with: thorium atom
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 15.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>phosphorus atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_710
preferred name: phosphorus atom

nanobud
type: Class
subclass of: nanostructured material
subclass of: Restriction
  on property: has part
  some values from: single-walled carbon nanotube
subclass of: Restriction
  on property: has part
  some values from: fullerene
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A nanostructured material which is formed by the combination of single-walled carbon nanotubes and fullerenes wherein the fullerenes are covalently bonded to the outer surface of the nanotubes.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanobud</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_711
comment: [definition source]: Nasibulin, A. G., Peter. V. Pikhitsa, Hua. Jiang, David. P. Brown, A. V. Krasheninnikov, Anton S. Anisimov, Paula Queipo, Anna Moisala, David Gonzalez, Gunther Lientschnig, Abdou Hassanien, Sergey D. Shandakov, Giulio Lolli, Daniel E. Resasco, Mansoo Choi, David Tománek, and Esko I. Kauppinen "A Novel Hybrid Carbon Nanomaterial". Nature Nanotechnology 2(3), 156-161 (2007).
preferred name: nanobud

homobifunctional crosslinker
type: Class
subclass of: crosslinking reagent
subclass of: Restriction
  on property: has part
  some values from: spacer
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A crosslinker which has two identical reactive ends connected by a carbon chain spacer and are used mostly to crosslink molecules or parts of molecules in a one-step chemical crosslinking procedure.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>homobifunctional crosslinker</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_713
preferred name: homobifunctional crosslinker

periodic table element
type: Class
equivalent class: Class
  union of: series element
  union of: period element
  union of: group element
  union of: block element
subclass of: element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of the periodic table of elements.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>periodic table element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_714
preferred name: periodic table element

drug release from nanoparticle in response to ultrasound
type: Class
subclass of: nanoparticle response to ultrasound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to ultrasound, which involves the release of drugs from a drug-loaded nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>drug release from nanoparticle in response to ultrasound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_715
preferred name: drug release from nanoparticle in response to ultrasound

thorium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: thorium
subclass of: Restriction
  on property: atomic Number
  has value: 90
subclass of: Restriction
  on property: is integral part of
  some values from: thorium
disjoint with: palladium atom
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 90.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thorium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_716
preferred name: thorium atom

external stimulus for nanoparticle function
type: Class
subclass of: stimulus for nanoparticle function
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A stimulus for nanoparticle function, which originates from a source that is outside of the the medium in which the nanoparticle is located.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>external stimulus for nanoparticle function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_717
preferred name: external stimulus for nanoparticle function

s-block element
type: Class
equivalent class: Class
  union of: alkali earth metal
  union of: Period 1 Element
  union of: alkali metal
subclass of: block element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electron is in an s-orbital.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>s-block element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_718
preferred name: s-block element

liposome
type: Class
subclass of: supramolecular entity
subclass of: Restriction
  on property: has part
  some values from: lipid bilayer
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A supramolecular structure which is a closed vesicle that forms on hydration of dry phospholipids above its transition temperature.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>liposome</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_719
preferred name: liposome
synonym: liposome vesicle

cyanate group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: has part
  some values from: cyano group
subclass of: Restriction
  on property: part of
  some values from: cyanate
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure N#C-O-. The group is characteristic of a cyanate molecule wherein it is attached to an organic group via a single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cyanate group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_720
preferred name: cyanate group

chitosan
type: Class
subclass of: polysaccharide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A linear polysaccharide of deacetylated beta-1,4-D-glucosamine; deacetylated chitin.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>chitosan</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: MESH:D048271
code: NPO_721
preferred name: chitosan

palladium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: palladium
subclass of: Restriction
  on property: atomic Number
  has value: 46
subclass of: Restriction
  on property: is integral part of
  all values from: palladium
disjoint with: gadolinium atom
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 46.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>palladium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_722
preferred name: palladium atom

nanocell
type: Class
subclass of: three-dimensional nanoparticle
subclass of: Restriction
  on property: has part
  some values from: lipid membrane
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A three-dimensional nanoparticle which consists of a nuclear core surrounded by a lighter lipid membrane.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanocell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_723
comment: Nanocell was first used for sequential delivery of anti-angiogenesis and chemotherapeutic agent to solid tumors.The chemotherapeutic agent can be conjugated to a nanoparticle in the core, while the anti-angiogenesis agent can be encapsulated in the lipid membrane.It was designed to first cause membrane disruption for release of anti-angiogenesis agent, which causes tumor vascular collapse, and finally cause intra-tumoral trapping of the core chemotherapeutic drug-conjugated nanoparticles.
comment: [definition source]: Sengupta et al, Nature Letters, vol 436, 2005
preferred name: nanocell

Nanocapsule
type: Class
subclass of: three-dimensional nanoparticle
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A three-dimensional nanoparticle which consists of a shell and a space, in which desired substances may be placed. It can be cylindrical or spherical in shape.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanocapsule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_724
preferred name: nanocapsule

amidine group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: amidine
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -E(=N-)-NH2, where E could denote carbon (C) or (Sulfur). The group is characteristic of an amidine compound.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>amidine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_725
preferred name: amidine group

technetium
type: Class
subclass of: element
disjoint with: neptunium
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 43.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>technetium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_726
preferred name: technetium

neptunium
type: Class
subclass of: element
disjoint with: silver
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 93.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>neptunium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_727
preferred name: neptunium

general collective quality
type: Class
subclass of: collective quality
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality which inheres in a group of multiple bearers AND NOT specific only to the type of bearers in the group.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>general collective quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_728
preferred name: general collective quality

iron oxide nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: iron oxide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of iron oxide.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>iron oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_729
preferred name: iron oxide nanoparticle

buckyball
type: Class
subclass of: fullerene
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Buckyball (C60) or Buckministerfullerene, is a type of fullerene which comprises of 60 carbon atoms arranged in interlocking hexagons and pentagons, like the patches on a soccer ball. Its geometry is roughly spherical and it has a hollow interior.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>buckyball</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_730
preferred name: buckyball

stimulus of heat
type: Class
subclass of: external stimulus for nanoparticle function
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by heat.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>stimulus of heat</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_731
preferred name: stimulus of heat

amphiphilic
type: Class
equivalent class: Class
  intersection of: Restriction
    on property: has part
    some values from: hydrophobic
  intersection of: Restriction
    on property: has part
    some values from: hydrophilic
subclass of: realizable_entity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable property which inheres in a molecule that has both hydrophobic and hydrophilic parts.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>amphiphilic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_732
synonym: amphipathic
preferred name: amphiphilic

element
type: Class
subclass of: pure substance
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A pure substance which is made up of one type of atom, and it cannot be decomposed or transformed by a chemical reaction into a different substance, although it can be transmutated into an isotope through a nuclear reaction.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_733
preferred name: element

dendrimer
type: Class
subclass of: polymer
subclass of: Restriction
  on property: has part
  some values from: dendrimer repeat unit
subclass of: Restriction
  on property: has part
  some values from: fiat dendrimer part
subclass of: Restriction
  on property: has quality
  some values from: dendrimer generation
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polymeric molecule which has a highly-branched, three-dimensional tree-like architecture, synthesized from monomers where shells of branched molecules are added in discrete steps to a central core.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dendrimer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: MESH:D050091
code: NPO_735
comment: [MeSH definition]: Tree-like, highly branched, polymeric compounds. They grow three-dimensionally by the addition of shells of branched molecules to a central core. The overall globular shape and presence of cavities gives potential as drug carriers and CONTRAST AGENTS.
comment: [NCI_THESAURUS definition]: A polymeric molecule which has a highly-branched, three-dimensional architecture. Dendrimers are synthesized from monomers and new branches are added in discrete steps to form a tree-like architecture. A high level of synthetic control is achieved through step-wise reactions and purification at each step to regulate the size, architecture, functionality and monodispersity of the molecules. These polymers have desirable pharmacokinetic properties and a polyvalent array of surface groups that make them potential drug delivery vesicles.
preferred name: dendrimer

silver
type: Class
subclass of: element
disjoint with: yttrium
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 47.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>silver</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_736
preferred name: silver

antineoplastic antibiotic
type: Class
equivalent class: Class
  intersection of: antineoplastic agent
  intersection of: Restriction
    on property: has role
    some values from: Class
      intersection of: antibiotic role
      intersection of: Restriction
        on property: is realized in
        some values from: inhibition of cancer cell growth
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antineoplastic agent isolated naturally from microorganisms or synthesized chemically that kills or inhibits the growth of tumor cells. Antineoplastic antibiotics can interfere with the normal function of cellular nucleic acids and proteins.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>antineoplastic antibiotic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C259
code: NPO_737
synonym: anticancer antibiotic
preferred name: antineoplastic antibiotic
synonym: antitumor antibiotic

amide linkage between primary amine and carboxylic ester
type: Class
subclass of: amide linkage
subclass of: Restriction
  on property: derives from
  some values from: carboxylic ester group
subclass of: Restriction
  on property: part of
  some values from: carboxamide group
subclass of: Restriction
  on property: derives from
  some values from: primary amine group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide linkage which is formed between a primary amine and a carboxylic ester.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>amide linkage between primary amine and carboxylic ester</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_738
preferred name: amide linkage between primary amine and carboxylic ester

yttrium
type: Class
subclass of: element
disjoint with: tin
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 39.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>yttrium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_739
preferred name: yttrium

acyl bromide group
type: Class
subclass of: acyl halide group
subclass of: Restriction
  on property: has part
  some values from: bromo group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acyl halide group in which the halogen atom is a "bromine atom."</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>acyl bromide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_740
preferred name: acyl bromide group

tin
type: Class
subclass of: element
disjoint with: xenon
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 50.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_742
preferred name: tin

instantaneous dipole-induced dipole interaction
type: Class
subclass of: dipole-dipole interaction
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dipole-dipole interaction between non-polar molecules due to attraction between an instantaneous dipole on one non-polar molecule and an induced dipole on the other non-polar molecule; the temporary dipole on the latter molecule is induced by the randomly occurring (temporary) instantaneous dipole of the former molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>instantaneous dipole-induced dipole interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_743
synonym: induced dipole-induced dipole interaction
preferred name: instantaneous dipole-induced dipole interaction
synonym: london force

Group 11 Element
type: Class
equivalent class: Class
  union of: copper
  union of: gold
  union of: roentgenium
  union of: silver
subclass of: group element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 11 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Group 11 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Group 11 Element
code: NPO_744
synonym: copper group element

carboxylic ester linkage
type: Class
subclass of: covalent linkage
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a carboxylic ester group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carboxylic ester linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_745
preferred name: carboxylic ester linkage
synonym: ester linkage

xenon
type: Class
subclass of: element
disjoint with: osmium
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 54.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>xenon</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_746
preferred name: xenon

sulfonamide group
type: Class
subclass of: amide group
subclass of: Restriction
  on property: part of
  some values from: sulfonamide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide group which has the structure -S(=O)-NH2 or -S(=O)-NH- or -S(=O)-N(-)-. The group is characteristic of a sulfonamide wherein it is attached to organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>sulfonamide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_747
preferred name: sulfonamide group

diazo linkage
type: Class
subclass of: covalent linkage
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a diazo group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>diazo linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_748
preferred name: diazo linkage

stimulus for nanoparticle function
type: Class
subclass of: process
subclass of: Restriction
  on property: stimulus causes response
  some values from: nanoparticle response to stimulus
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process which describes an action or event that triggers a specific function of a nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>stimulus for nanoparticle function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_751
preferred name: stimulus for nanoparticle function

internal stimulus for nanoparticle function
type: Class
subclass of: stimulus for nanoparticle function
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A stimulus for nanoparticle function, which originates from a source that is inside the medium in which the nanoparticle is located.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>internal stimulus for nanoparticle function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_752
preferred name: internal stimulus for nanoparticle function

gadolinium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: gadolinium
subclass of: Restriction
  on property: atomic Number
  has value: 64
subclass of: Restriction
  on property: is integral part of
  all values from: gadolinium
disjoint with: cerium atom
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 64.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gadolinium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_753
preferred name: gadolinium atom

osmium
type: Class
subclass of: element
disjoint with: zirconium
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 76.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>osmium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_754
preferred name: osmium

metalloid
type: Class
equivalent class: Class
  union of: germanium
  union of: boron
  union of: polonium
  union of: silicon
  union of: antimony
  union of: tellurium
  union of: arsenic
subclass of: series element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with properties between a metal and a non-metal.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>metalloid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_755
preferred name: metalloid

nanoparticle response to infrared light
type: Class
subclass of: nanoparticle response to external stimulus
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to external stimulus, which occurs in response to infrared light.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanoparticle response to infrared light</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_756
preferred name: nanoparticle response to infrared light

cerium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: cerium
subclass of: Restriction
  on property: is integral part of
  some values from: cerium
subclass of: Restriction
  on property: atomic Number
  has value: 58
disjoint with: cadmium atom
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 58.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cerium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_757
preferred name: cerium atom

chloro group
type: Class
subclass of: halo group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A halo group in which the halogen atom is a chlorine atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>chloro group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_758
preferred name: chloro group

nanofilm
type: Class
subclass of: nanostructured material
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A thin layer of nanostructured material.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanofilm</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_759
preferred name: nanofilm

shell
type: Class
subclass of: fiat material part
subclass of: Restriction
  on property: has quality
  some values from: shell composition
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A fiat material part which is a material layer surrounding the core.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>shell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_760
preferred name: shell

cadmium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 48
subclass of: Restriction
  on property: is integral part of
  some values from: cadmium
subclass of: Restriction
  on property: is integral part of
  all values from: cadmium
disjoint with: silver atom
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 48.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cadmium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_761
preferred name: cadmium atom

silicon nanotube
type: Class
equivalent class: Class
  intersection of: nanotube
  intersection of: Restriction
    on property: has part
    some values from: silicon
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanotube which consists of one or more sheets of hexagonal arrays of silicon rolled into seamless cylinders with capped ends.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>silicon nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_762
preferred name: silicon nanotube

water-dispersible
type: Class
subclass of: realizable_entity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity inhering in particles (e.g, nanoparticles), which gives the bearer the ability to disperse in an aqueous medium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>water-dispersible</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_763
preferred name: water-dispersible

organic compound or molecule
type: Class
equivalent class: Class
  intersection of: compound by chemical composition
  intersection of: Restriction
    on property: has quality
    some values from: organic
subclass of: Restriction
  on property: has part
  some values from: carbon
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule, in which carbon is the principal element.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>organic compound or molecule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_764
synonym: organic compound
preferred name: organic compound or molecule
synonym: organic molecule

zirconium
type: Class
subclass of: element
disjoint with: promethium
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 40.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>zirconium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_765
preferred name: zirconium

charge-dipole interaction
type: Class
subclass of: intermolecular interaction
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An intermolecular interaction between an ion and a polar molecule by virtue of an attraction between the ionic charge and a permanent dipole on the polar molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>charge-dipole interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_766
preferred name: charge-dipole interaction
comment: the polar molecule has permanent molecular dipole moment.

stimulus of ultraviolet light
type: Class
subclass of: stimulus of light
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by ultraviolet light.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>stimulus of ultraviolet light</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_767
preferred name: stimulus of ultraviolet light

nanopore
type: Class
subclass of: material site
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A material site which is a nanoscale cavity or channel confined within a membrane or solid matter.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanopore</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C62343
code: NPO_768
comment: [NCI_Thesaurus definition]: A nanoscale cavity or channel confined within a membrane or solid matter.
preferred name: nanopore

silver atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 47
subclass of: Restriction
  on property: is integral part of
  all values from: silver
subclass of: Restriction
  on property: is integral part of
  some values from: silver
disjoint with: molybdenum atom
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 47.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>silver atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_770
preferred name: silver atom

hydrogel
type: Class
equivalent class: Class
  intersection of: gel
  intersection of: Restriction
    on property: has part
    some values from: water
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A colloidal gel in which water is the dispersion medium.[source: WordNet 2008]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydrogel</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_771
preferred name: hydrogel

molybdenum atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: molybdenum
subclass of: Restriction
  on property: atomic Number
  has value: 42
subclass of: Restriction
  on property: is integral part of
  some values from: molybdenum
disjoint with: scandium atom
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 42.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>molybdenum atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_772
preferred name: molybdenum atom

promethium
type: Class
subclass of: element
disjoint with: terbium
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 61.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>promethium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_773
preferred name: promethium

terbium
type: Class
subclass of: element
disjoint with: actinium
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 65.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>terbium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_775
preferred name: terbium

dendrimer branch
type: Class
subclass of: fiat material part
subclass of: Restriction
  on property: part of
  some values from: dendrimer generation layer
subclass of: Restriction
  on property: has part
  some values from: dendrimer repeat unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular structure which is a branch of a dendrimer, formed by the dendrimer's repeating units.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dendrimer branch</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_776
preferred name: dendrimer branch

tumor angiogenesis inhibition
type: Class
subclass of: antitumor activity
subclass of: Restriction
  on property: realizes
  some values from: inhibitor role
subclass of: Restriction
  on property: negatively regulates
  some values from: tumor angiogenesis
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process or mechanism which inhibits tumor angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tumor angiogenesis inhibition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C26044
code: NPO_778
synonym: inhibition of tumor angiogenesis
preferred name: tumor angiogenesis inhibition
synonym: tumor angiogenic inhibition

nanosensor
type: Class
subclass of: nanodevice
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as a sensor/detector of any activity, phenomenon or molecule, within a nanometer-range resolution; it responds to a stimulus by sending a signal that can be measured.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanosensor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C62374
code: NPO_779
preferred name: nanosensor

actinium
type: Class
subclass of: element
disjoint with: lithium
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 89.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>actinium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_781
preferred name: actinium

lithium
type: Class
subclass of: element
disjoint with: cobalt
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 3.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>lithium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_782
preferred name: lithium

topoisomerase-II inhibitor
type: Class
equivalent class: Class
  intersection of: topoisomerase inhibitor
  intersection of: Restriction
    on property: has role
    some values from: Class
      intersection of: inhibitor role
      intersection of: Restriction
        on property: is realized in
        some values from: inhibition of DNA topoisomerase type II activity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Topoisomerase inhibitor which either stabilizes DNA-protein complexes damaging DNA (e g., teniposide), or inhibits the catalytic activity of the topoisomerase (e.g., merbarone).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>topoisomerase-II inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C1968
code: NPO_784
preferred name: topoisomerase-II inhibitor
synonym: type II topoisomerase inhibitor

gas
type: Class
equivalent class: Class
  intersection of: fluid
  intersection of: Restriction
    on property: has quality
    some values from: gaseous state
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fluid having neither independent shape nor volume and being able to expand indefinitely.[source:NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gas</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C45299
code: NPO_785
preferred name: gas

non-polar
type: Class
subclass of: polarity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality that inheres in a molecule or chemical bond due to the absence of dipole moments.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>non-polar</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_786
preferred name: non-polar

scandium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: scandium
subclass of: Restriction
  on property: is integral part of
  some values from: scandium
subclass of: Restriction
  on property: atomic Number
  has value: 21
disjoint with: thulium atom
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 21.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>scandium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_787
preferred name: scandium atom

aromatic aminoacid
type: Class
equivalent class: Class
  intersection of: aminoacid
  intersection of: Restriction
    on property: has part
    some values from: Class
      intersection of: alpha-aminoacid sidechain
      intersection of: Restriction
        on property: has quality
        some values from: aromatic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aminoacid which is aromatic in nature.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>aromatic aminoacid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_791
preferred name: aromatic aminoacid

outer surface of nanotube
type: Class
subclass of: material boundary
subclass of: Restriction
  on property: part of
  some values from: nanotube
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The outer surface of a nanotube to which other molecular entities can be attached. (For example, attachment of fullerene on the surface of carbon nanotube.)</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>outer surface of nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_792
preferred name: outer surface of nanotube

zero-length crosslinker
type: Class
subclass of: crosslinking reagent
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cross-linking agent for mediating the conjugation of two molecules by forming a bond between functional groups of the molecule while containing no additional atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>zero-length crosslinker</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_794
preferred name: zero-length crosslinker

cobalt
type: Class
subclass of: element
disjoint with: sulfur
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 27.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cobalt</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_795
preferred name: cobalt

sulfur
type: Class
subclass of: element
disjoint with: tungsten
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 16.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>sulfur</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_796
preferred name: sulfur

thioether
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: thioether group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thioether is an organic compound which is characterized by the presence of a thioether group. It has the structure R-S-R', where R, R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thioether</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_797
preferred name: thioether

tungsten
type: Class
subclass of: element
disjoint with: nickel
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 74.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tungsten</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_799
preferred name: tungsten

PEGylated nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: Class
      intersection of: poly(ethylene glycol)
      intersection of: Restriction
        on property: has role
        some values from: nanoparticle surface modifying role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a coating agent composed of polyethylene glycol.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>PEGylated nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_801
synonym: PEG-coated nanoparticle
synonym: PEG-modified nanoparticle
preferred name: PEGylated nanoparticle
synonym: poly(ethylene) glycol-coated nanoparticle

organic
type: Class
subclass of: independent specific individual quality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality that inheres in a molecular entity which contains carbon as a principal element.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>organic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C63848
code: NPO_802
comment: definition for organic is based on the CHEBI definition for organic compounds (CHEBI:25700)
preferred name: organic

dendrimer core molecule
type: Class
subclass of: fiat dendrimer part
subclass of: Restriction
  on property: has identification type
  some values from: compound or molecule
subclass of: Restriction
  on property: part of
  some values from: dendrimer core
subclass of: Restriction
  on property: has identification type
  all values from: compound or molecule
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecule component in dendrimer which forms the core of a dendrimer.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dendrimer core molecule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_803
synonym: core initiator group
preferred name: dendrimer core molecule

nickel
type: Class
subclass of: element
disjoint with: rutherfordium
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 28.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nickel</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_804
preferred name: nickel

thulium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: thorium
subclass of: Restriction
  on property: atomic Number
  has value: 69
subclass of: Restriction
  on property: is integral part of
  all values from: thorium
disjoint with: arsenic atom
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 69.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thulium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_806
preferred name: thulium atom

amide linkage between primary amine and carboxylic acid
type: Class
subclass of: amide linkage
subclass of: Restriction
  on property: part of
  some values from: carboxamide group
subclass of: Restriction
  on property: derives from
  some values from: primary amine group
subclass of: Restriction
  on property: derives from
  some values from: carboxyl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide linkage which is formed between a primary amine and a carboxylic acid.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>amide linkage between primary amine and carboxylic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_807
preferred name: amide linkage between primary amine and carboxylic acid

arsenic atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 33
subclass of: Restriction
  on property: is integral part of
  all values from: arsenic
subclass of: Restriction
  on property: is integral part of
  some values from: arsenic
disjoint with: titanium atom
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 33.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>arsenic atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_808
preferred name: arsenic atom

rutherfordium
type: Class
subclass of: element
disjoint with: ruthenium
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 104.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>rutherfordium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_809
preferred name: rutherfordium

titanium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 22
subclass of: Restriction
  on property: is integral part of
  all values from: titanium
subclass of: Restriction
  on property: is integral part of
  some values from: titanium
disjoint with: bromine atom
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 22.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>titanium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_810
preferred name: titanium atom

stimulus of temperature change
type: Class
subclass of: internal stimulus for nanoparticle function
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An internal stimulus for nanoparticle function, which is caused by a change in temperature.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>stimulus of temperature change</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_811
preferred name: stimulus of temperature change

bromine atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 35
subclass of: Restriction
  on property: is integral part of
  some values from: bromine
subclass of: Restriction
  on property: is integral part of
  all values from: bromine
disjoint with: tellurium atom
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 35.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>bromine atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_812
preferred name: bromine atom

tellurium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: tellurium
subclass of: Restriction
  on property: is integral part of
  some values from: tellurium
subclass of: Restriction
  on property: atomic Number
  has value: 52
disjoint with: darmstadtium atom
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 52.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tellurium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_813
preferred name: tellurium atom

fluid
type: Class
equivalent class: Class
  intersection of: chemical substance by physical state
  intersection of: Restriction
    on property: has quality
    some values from: fluid state
subclass of: Restriction
  on property: has property
  some values from: viscosity
subclass of: Restriction
  on property: has quality
  some values from: volume
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A chemical substance which deforms under an applied stress, and conforms to the outline of its container.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fluid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C25278
code: NPO_815
preferred name: fluid

ruthenium
type: Class
subclass of: element
disjoint with: zinc
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 44.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ruthenium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_816
preferred name: ruthenium

zinc
type: Class
subclass of: element
disjoint with: argon
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 30.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>zinc</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_818
preferred name: zinc

darmstadtium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: darmstadtium
subclass of: Restriction
  on property: is integral part of
  all values from: darmstadtium
subclass of: Restriction
  on property: atomic Number
  has value: 110
disjoint with: berkelium atom
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 110.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>darmstadtium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_819
preferred name: darmstadtium atom

polydispersity
type: Class
subclass of: independent specific collective quality
subclass of: Restriction
  on property: quality of
  some values from: Class
    union of: nanoparticle sample
    union of: nanoparticle formulation
    union of: polymer
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a collection of objects based on size or molecular weights (e.g., particles, polymers).</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>polydispersity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_821
preferred name: polydispersity

phosphoramide group
type: Class
subclass of: amide group
subclass of: Restriction
  on property: part of
  some values from: phosphoramide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide group which has the structure -P(=O)-NH2 or -P(=O)-NH- or -P(=O)-N(-)-. The group is characteristic of a phosphoramide wherein it is attached to organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>phosphoramide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_822
preferred name: phosphoramide group

monoclonal antibody
type: Class
subclass of: antibody
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antibody produced by a clone or genetically homogenous fast-growing cells i.e., hybridoma. Hybridoma cells are cloned to establish cell lines producing a specific antibody that is chemically and immunologically homogeneous.[source: NCI_Thesaurus]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>monoclonal antibody</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: MAb
DB xref ID: NCIT:C20401
code: NPO_823
preferred name: monoclonal antibody

carboxamide group
type: Class
subclass of: amide group
subclass of: Restriction
  on property: part of
  some values from: carboxamide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A amide group which has the structure -C(=O)-NH2 or -C(=O)-NH- or -C(=O)-N(-)-. The group is characteristic of a carboxamide wherein it is attached to organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carboxamide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_824
preferred name: carboxamide group

fluoro group
type: Class
subclass of: halo group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A halo group in which the halogen atom is a fluorine atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fluoro group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_825
preferred name: fluoro group

surface modifying agent
type: Class
equivalent class: Class
  intersection of: chemical component in nanoparticle formulation
  intersection of: Restriction
    on property: has role
    some values from: nanoparticle surface modifying role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component in a nanoparticle formulation, which is there to modify the nanoparticle's surface properties like surface charge or surface hydrophilicity; or 2) to which other molecular entities can be attached for facilitating linkage between the molecular entities and the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanoparticle surface modifying agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_827
synonym: coating agent
preferred name: nanoparticle surface modifying agent

micelle
type: Class
subclass of: supramolecular entity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A supramolecular structure which is an aggregate of amphiphilic molecules in a polar solvent.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>micelle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_829
preferred name: micelle

target role
type: Class
subclass of: molecular role
subclass of: Restriction
  on property: role of
  some values from: target
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Role played by a material entity that serves as the target for a targeting agent in a targeting process.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>target role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_830
synonym: role of a target
preferred name: target role

carboxylate group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: carboxylate
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group derived by the removal of a hydrogen atom from a carboxylic acid, by virtue of which it has structure -C(=O)-[O-]. The group is characteristic of a carboxylate compound wherein it is attached to the remaining part of the molecule via a covalent bond between the oxygen atom and a carbon atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carboxylate group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_831
preferred name: carboxylate group

porous shell of nanocage
type: Class
subclass of: shell
subclass of: Restriction
  on property: part of
  some values from: nanocage
subclass of: Restriction
  on property: part of
  all values from: nanocage
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The porous shell of a nanocage.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>porous shell of nanocage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_833
preferred name: porous shell of nanocage

solid
type: Class
equivalent class: Class
  intersection of: chemical substance by physical state
  intersection of: Restriction
    on property: has quality
    some values from: solid state
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A substance which has an ordered 3-dimensional structure due to the closely packed arrangement of constituting atoms, molecules or ions. As a result, the substance has a definite shape and volume, and the shape can be modified under application of a force.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>solid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_834
preferred name: solid

sol
type: Class
equivalent class: Class
  intersection of: colloid
  intersection of: Restriction
    on property: has quality
    some values from: state of sol
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A colloid that has a continuous liquid phase in which a solid is suspended in a liquid.[source: WordNet 2008]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>sol</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C73489
code: NPO_835
preferred name: sol

biodegradable nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Class
    union of: Restriction
      on property: has component part
      some values from: Class
        intersection of: molecular entity
        intersection of: Restriction
    union of: Restriction
      on property: has property
      some values from: biodegradable
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a biodegradable property.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>biodegradable nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_836
preferred name: biodegradable nanoparticle

enhanced permeability and retention effect
type: Class
subclass of: passive targeting
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A passive targeting process, which results in the accumulation of particulate substances in angiogenic tumors due to enhanced permeability of particles across leaky tumor endothelium and retention of the particles inside the tumor due to its defective lymphatic drainage system.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>enhanced permeability and retention effect</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: EPR
code: NPO_837
comment: [definition source]: Y. Matsumur and H. Maeda, A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent Smancs, Cancer Research, 46, 6387-6392 (1986).
preferred name: enhanced permeability and retention effect
synonym: targeting of cancer cells via EPR

argon
type: Class
subclass of: element
disjoint with: americium
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 18.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>argon</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_841
preferred name: argon

americium
type: Class
subclass of: element
disjoint with: plutonium
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 95.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>americium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_842
preferred name: americium

arylamine linkage
type: Class
subclass of: covalent linkage
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an arylamine group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>arylamine linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_843
preferred name: arylamine linkage

isothiocyanate
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: isothiocyanate group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An isothiocyanate is an organic compound which is characterized by the presence of an isothiocyanate group. It has the structure R-N=C=S, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>isothiocyanate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_844
preferred name: isothiocyanate

p-block element
type: Class
equivalent class: Class
  union of: Group 16 Element
  union of: radon
  union of: Group 13 Element
  union of: Group 14 Element
  union of: neon
  union of: Group 15 Element
  union of: Group 17 Element
  union of: xenon
  union of: argon
  union of: krypton
subclass of: block element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electrons occupy p-orbitals.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>p-block element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_845
preferred name: p-block element

dextran
type: Class
subclass of: glucan
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A glucan which is a high-molecular-weight polymer of d-glucose, produced by enzymes on the cell surface of certain lactic acid bacteria.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dextran</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: MESH:D003911
code: NPO_846
preferred name: dextran

plutonium
type: Class
subclass of: element
disjoint with: fermium
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 94.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>plutonium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_847
preferred name: plutonium

polypeptide
type: Class
subclass of: peptide
subclass of: Restriction
  on property: has part
  some values from: aminoacid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A peptide which consists of several aminoacids .</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>polypeptide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_848
preferred name: polypeptide

Period 7 Element
type: Class
equivalent class: Class
  union of: francium
  union of: Actinide
  union of: seaborgium
  union of: meitnerium
  union of: dubnium
  union of: bohrium
  union of: darmstadtium
  union of: roentgenium
  union of: hassium
  union of: radium
  union of: rutherfordium
subclass of: period element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element in the seventh row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Period 7 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_849
preferred name: Period 7 Element

elliptical shape
type: Class
subclass of: shape
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shape formed by a closed, curve whose path is traced by a point moving in a plane such that the sum of its respective distances from two fixed points (the ellipse's foci) is constant.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>elliptical shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_850
comment: [definition based on source]:http://www.cycfoundation.org, http://www.thefreedictionary.com, NCI
synonym: elliptical
preferred name: elliptical shape

fermium
type: Class
subclass of: element
disjoint with: carbon
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 100.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fermium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_851
preferred name: fermium

needle shape
type: Class
subclass of: rod-shaped
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A rod shape inhering in a long and slender rod, which resembles a needle.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>needle shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_852
preferred name: needle shape

vapor
type: Class
equivalent class: Class
  intersection of: gas
  intersection of: Restriction
    on property: has quality
    some values from: vapor state
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A gas that is a solid or liquid at normal room temperature. [source:NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>vapor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C63390
code: NPO_854
preferred name: vapor

aliphatic aminoacid
type: Class
equivalent class: Class
  intersection of: aminoacid
  intersection of: Restriction
    on property: has part
    some values from: Class
      intersection of: alpha-aminoacid sidechain
      intersection of: Restriction
        on property: has quality
        some values from: aliphatic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aminoacid which is aliphatic in nature.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>aliphatic aminoacid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_855
preferred name: aliphatic aminoacid

berkelium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 97
subclass of: Restriction
  on property: is integral part of
  some values from: berkelium
subclass of: Restriction
  on property: is integral part of
  all values from: berkelium
disjoint with: xenon atom
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 97.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>berkelium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_856
preferred name: berkelium atom

carbon
type: Class
subclass of: element
disjoint with: molybdenum
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 6.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carbon</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_857
preferred name: carbon

polyhedral shape
type: Class
subclass of: shape
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shape inhering in a 3-dimensional object that resembles a solid figure bounded by plane polyons or faces.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>polyhedral shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_858
comment: [source]: WordNet
synonym: polyhedral
preferred name: polyhedral shape

superparamagnetic
type: Class
subclass of: magnetic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Magnetic property -similar to paramagnetism - which is exhibited in materials when the temperature of the material is below the Curie temperature.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>superparamagnetic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_859
preferred name: superparamagnetic

cubical shape
type: Class
subclass of: hexahedral shape
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A regular hexahedral shape that inheres in a 3-dimensional object having six equal squares as faces.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cubical shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_861
comment: [source]:WordNet
synonym: cubical
preferred name: cubical shape

xenon atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: xenon
subclass of: Restriction
  on property: atomic Number
  has value: 54
subclass of: Restriction
  on property: is integral part of
  all values from: xenon
disjoint with: holmium atom
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 54.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>xenon atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_862
preferred name: xenon atom

holmium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 67
subclass of: Restriction
  on property: is integral part of
  some values from: holmium
subclass of: Restriction
  on property: is integral part of
  all values from: holmium
disjoint with: copper atom
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 67.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>holmium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_863
preferred name: holmium atom

topoisomerase-I inhibitor
type: Class
equivalent class: Class
  intersection of: topoisomerase inhibitor
  intersection of: Restriction
    on property: has role
    some values from: Class
      intersection of: inhibitor role
      intersection of: Restriction
        on property: is realized in
        some values from: inhibition of DNA topoisomerase type I activity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Topoisomerase inhibitor which inhibits the action of topoisomerase I.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>topoisomerase-I inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_864
preferred name: topoisomerase-I inhibitor

copper atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: copper
subclass of: Restriction
  on property: atomic Number
  has value: 29
subclass of: Restriction
  on property: is integral part of
  all values from: copper
disjoint with: beryllium atom
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 29.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>copper atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_865
preferred name: copper atom

acryloyl compound
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: acryloyl group
subclass of: Restriction
  on property: has part
  some values from: acyl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acryloyl compound is an "organic compound" which is characterized by the presence of an "acryloyl group". It has the structure R-C(=O)-CH=CH2, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>acryloyl compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_866
preferred name: acryloyl compound
synonym: acryloyl derivative

polydisperse
type: Class
subclass of: polydispersity
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A qualitative measure of polydispersity, inhering in a collection of particles that are of different sizes or of polymers that have varying molecular weights.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>polydisperse</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_867
preferred name: polydisperse

nanoparticle formulation
type: Class
subclass of: nanomaterial
subclass of: Restriction
  on property: has component part
  some values from: Class
    union of: nanoparticle component
    union of: nanoparticle
subclass of: Restriction
  on property: has quality
  some values from: purity
subclass of: Restriction
  on property: has quality
  some values from: polydispersity
subclass of: Restriction
  on property: has part
  some values from: linkage
subclass of: Restriction
  on property: has quality
  some values from: physical state
subclass of: Restriction
  on property: has component part
  some values from: medium
subclass of: Restriction
  on property: has component part
  all values from: Class
    union of: chemical component in nanoparticle formulation
    union of: chemical entity
    union of: nanoparticle
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A nanomaterial which is a particulate chemical substance that is formulated systematically using nanotechnology, and it contains nanoparticles and active chemical components/ingredients.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanoparticle formulation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_868
comment: Nanotechnology involves the application of scientific knowledge from multidisciplinary fields of science and engineering, towards understanding, manipulating and controlling the properties of matter at the nanoscale (1-100 nm) size dimensions.
preferred name: nanoparticle formulation

beryllium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: beryllium
subclass of: Restriction
  on property: atomic Number
  has value: 4
subclass of: Restriction
  on property: is integral part of
  all values from: beryllium
disjoint with: californium atom
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 4.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>beryllium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_869
preferred name: beryllium atom

single-walled nanohorn
type: Class
subclass of: nanohorn
subclass of: Restriction
  on property: has component part
  some values from: carbon
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanohorn that is comprised of a single layer of graphitic carbon and exhibits an irregular horn-like shape. One of the primary characteristics of carbon nanohorns is their ability to aggregate. This aggregation is advantageous because of the resulting enhanced permeability in both gases and liquids.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>single-walled nanohorn</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C62387
code: NPO_870
comment: [definition source]: NCI_Thesaurus
preferred name: single-walled nanohorn

Period 4 Element
type: Class
equivalent class: Class
  union of: germanium
  union of: calcium
  union of: gallium
  union of: manganese
  union of: chromium
  union of: copper
  union of: vanadium
  union of: iron
  union of: arsenic
  union of: potassium
  union of: cobalt
  union of: nickel
  union of: zinc
  union of: titanium
  union of: scandium
  union of: krypton
  union of: selenium
  union of: bromine
subclass of: period element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element in the fourth row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Period 4 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_871
preferred name: Period 4 Element

californium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: californium
subclass of: Restriction
  on property: is integral part of
  some values from: californium
subclass of: Restriction
  on property: atomic Number
  has value: 98
disjoint with: carbon atom
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 98.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>californium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_872
preferred name: californium atom

antimetastatic agent
type: Class
equivalent class: Class
  intersection of: antineoplastic agent
  intersection of: Restriction
    on property: has role
    some values from: Class
      intersection of: inhibitor role
      intersection of: Restriction
        on property: is realized in
        some values from: inhibition of metastasis
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antineoplastic agent, which prevents or impairs tumor metastasis.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>antimetastatic agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C2196
code: NPO_873
preferred name: antimetastatic agent

melphalan
type: Class
subclass of: nitrogen mustard
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: therapeutic function
    intersection of: Restriction
      on property: is realized in
      some values from: antineoplastic activity
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: alkylating function
    intersection of: Restriction
      on property: is realized in
      some values from: DNA alkylation
subclass of: Restriction
  on property: has role
  some values from: anticancer drug role
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: binding function
    intersection of: Restriction
      on property: is realized in
      some values from: DNA binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An L-phenylalanine nitrogen mustard.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>melphalan</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C633
code: NPO_874
comment: anticancer drug that induces breakage of DNA helix
preferred name: melphalan

dihydrofolate reductase inhibitor
type: Class
equivalent class: Class
  intersection of: enzyme inhibitor drug
  intersection of: Restriction
    on property: has role
    some values from: Class
      intersection of: inhibitor role
      intersection of: Restriction
        on property: is realized in
        some values from: inhibition of dihydrofolate reductase activity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Enzyme inhibitor that inhibits dihydrofolate reductase by interfering with the conversion of Dihydrofolate to Tetrahydrofolate, causing inhibition of nucleotide biosynthesis and protein synthesis.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dihydrofolate reductase inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C2153
code: NPO_876
preferred name: dihydrofolate reductase inhibitor

carbon atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 6
subclass of: Restriction
  on property: is integral part of
  some values from: carbon
subclass of: Restriction
  on property: is integral part of
  all values from: carbon
disjoint with: seaborgium atom
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 6.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carbon atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_877
preferred name: carbon atom

stimulus of visible light
type: Class
subclass of: stimulus of light
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by visible light.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>stimulus of visible light</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_878
preferred name: stimulus of visible light

molybdenum
type: Class
subclass of: element
disjoint with: helium
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 42.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>molybdenum</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_880
preferred name: molybdenum

hydrophobic core of micelle
type: Class
subclass of: core site
subclass of: Restriction
  on property: part of
  some values from: micelle
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Core part of a micelle formed by hydrophobic (non-polar) tails of individual amphiphilic molecules that form the whole micelle in a polar solvent, which has void spaces to include other hydrophobic molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydrophobic core of micelle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_881
preferred name: hydrophobic core of micelle

seaborgium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 106
subclass of: Restriction
  on property: is integral part of
  all values from: seaborgium
subclass of: Restriction
  on property: is integral part of
  some values from: seaborgium
disjoint with: barium atom
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 106.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>seaborgium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_885
preferred name: seaborgium atom

permanent dipole-dipole interaction
type: Class
subclass of: dipole-dipole interaction
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An dipole-dipole interaction between two polar molecules due to attraction between their permanent dipoles.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>permanent dipole-dipole interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_886
preferred name: permanent dipole-dipole interaction

disulfide linkage between two thiols
type: Class
subclass of: disulfide linkage
subclass of: Restriction
  on property: part of
  some values from: disulfanedyl group
subclass of: Restriction
  on property: derives from
  some values from: sulfhydryl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disulfide linkage which is formed between two thiol compounds, through covalent interactions between atoms of respective sulfhydryl groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>disulfide linkage between two thiols</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_887
preferred name: disulfide linkage between two thiols

physical state
type: Class
subclass of: independent general individual quality
subclass of: Restriction
  on property: quality of
  some values from: chemical substance by physical state
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality, which is the physical condition of a material entity, based on its chemical composition and structure.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>physical state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_888
preferred name: physical state
synonym: state of matter

secondary amine group
type: Class
subclass of: amine group
subclass of: Restriction
  on property: part of
  some values from: secondary amine
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amine group which is formally derived by the removal of two hydrogen atoms from ammonia, by virtue of which it has the structure -NH-. The group is characteristic of a secondary amine molecule wherein it is attached to hydrocarbyl groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>secondary amine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_889
preferred name: secondary amine group

amide linkage between primary amine and acyl azide
type: Class
subclass of: amide linkage
subclass of: Restriction
  on property: part of
  some values from: carboxamide group
subclass of: Restriction
  on property: derives from
  some values from: primary amine group
subclass of: Restriction
  on property: derives from
  some values from: acyl azide group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide linkage which is formed between a primary amine and an acyl azide.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>amide linkage between primary amine and acyl azide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_891
preferred name: amide linkage between primary amine and acyl azide

monodisperse
type: Class
subclass of: polydispersity
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A qualitative measure of polydispersity, inhering in a collection of particles that are of the same size or of polymers that have uniform distribution of molecular weights.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>monodisperse</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_892
preferred name: monodisperse

nanofiber
type: Class
subclass of: two-dimensional nano-object
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A two-dimensional nano-object which is an elongated fiber of diameter less than 100 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanofiber</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_893
preferred name: nanofiber

acid anhydride group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: acid anhydride
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=O)-O-C(=O)-. The group is characteristic of acid anhydrides.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>acid anhydride group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_894
comment: The structure of an acid anhydride is R-C(=O)-O-C(=O)-R', in which two acyl groups are bonded to the same oxygen atom; and , R,R' denote hydrogen atoms or organic groups.
preferred name: acid anhydride group

crystal
type: Class
equivalent class: Class
  intersection of: solid
  intersection of: Restriction
    on property: has quality
    some values from: crystalline state
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A solid which is formed by the solidification of a chemical and having a highly regular atomic structure.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>crystal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C61303
code: NPO_895
preferred name: crystal
synonym: crystalline solid

barium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 56
subclass of: Restriction
  on property: is integral part of
  some values from: barium
subclass of: Restriction
  on property: is integral part of
  all values from: barium
disjoint with: chromium atom
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 56.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>barium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_897
preferred name: barium atom

aryl halide
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: aryl halide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound in which a halogen atom is bonded to a carbon atom that is part of an aromatic ring. It is characterized by the presence of aryl halide groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>aryl halide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_898
preferred name: aryl halide

pathologic process
type: Class
subclass of: biological process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A biological process having an abnormal or deleterious effect at the subcellular, cellular, multicellular, or organismal level. (NCI)</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>pathologic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C16956
code: NPO_899
preferred name: pathologic process

helium
type: Class
subclass of: element
disjoint with: sodium
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 2.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>helium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_901
preferred name: helium

active targeting
type: Class
subclass of: tumor targeting
subclass of: Restriction
  on property: has participant
  some values from: Class
    intersection of: molecular entity
    intersection of: Restriction
      on property: has role
      some values from: targeting role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The process in which material entities (e.g., nanoparticles) are targeted to tumor sites, cancer cells or intracellular organelles in cancer cells, with the help of molecular agents (conjugated to the material entities) that recognize and bind to specific biological molecules at the target location.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>active targeting</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_903
preferred name: active targeting

folate receptor mediated endocytosis
type: Class
subclass of: receptor mediated endocytosis
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Receptor mediated endocytosis, which is the process by which cells internalize folate molecules that specifically bind to folate receptors.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>folate receptor mediated endocytosis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_904
preferred name: folate receptor mediated endocytosis

three-dimensional nanoparticle
type: Class
subclass of: nanoparticle
synonym: 3-D nanoparticle
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has all three external dimensions in the nanoscale size range.</ncicp:def-definition><ncicp:Definition_Review_Date>101223</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>three-dimensional nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_905
preferred name: three-dimensional nanoparticle

sodium
type: Class
subclass of: element
disjoint with: titanium
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 11.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>sodium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_907
preferred name: sodium

epoxide group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: epoxide compound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has a three-membered cyclic ether structure, where an oxygen atom is attached to two carbon atoms and the carbon atoms are bonded to each other via single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>epoxide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_909
preferred name: epoxide group
synonym: oxirane group

Period 6 Element
type: Class
equivalent class: Class
  union of: iridium
  union of: mercury
  union of: radon
  union of: caesium
  union of: tantalum
  union of: polonium
  union of: Lanthanide
  union of: barium
  union of: lead
  union of: rhenium
  union of: thallium
  union of: gold
  union of: astatine
  union of: platinum
  union of: bismuth
  union of: osmium
  union of: tungsten
  union of: hafnium
subclass of: period element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element in the sixth row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Period 6 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_911
preferred name: Period 6 Element

inhibition of cancer cell growth
type: Class
subclass of: antitumor activity
subclass of: Restriction
  on property: realizes
  some values from: inhibitor role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process which inhibits or blocks the induction, promotion, maintenance, or completion of cell division in cancer cells.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>inhibition of cancer cell growth</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT: C29895
code: NPO_914
preferred name: inhibition of cancer cell growth

powder
type: Class
equivalent class: Class
  intersection of: solid
  intersection of: Restriction
    on property: has quality
    some values from: powdered state
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A solid which corresponds to tiny loose particles, produced by pulverization.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>powder</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C45302
code: NPO_915
preferred name: powder

unilamellar vesicle
type: Class
subclass of: liposome
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A liposome vesicle that has a single lipid bilayer.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>unilamellar vesicle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_916
preferred name: unilamellar vesicle

drug directed against membrane receptor
type: Class
subclass of: drug directed against protein of tumor cell
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug directed to interfere with the activity of a membrane protein receptor of the tumor cell.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>drug directed against membrane receptor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_917
preferred name: drug directed against membrane receptor

acoustic imaging contrast agent
type: Class
subclass of: contrast agent
subclass of: Restriction
  on property: has property
  some values from: acoustic-sensitive
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A contrast agent, which provides contrast in images captured using acoustic imaging techniques.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>acoustic imaging contrast agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_918
preferred name: acoustic imaging contrast agent

antitumor activity
type: Class
subclass of: antineoplastic activity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An activity, which involves the killing of tumor cells; or which causes reduction of tumor size.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>antitumor activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_919
preferred name: antitumor activity

purine antagonist
type: Class
subclass of: antineoplastic antimetabolite
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic antimetabolite which affects the metabolism and utilization of purines.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>purine antagonist</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C1556
code: NPO_920
preferred name: purine antagonist
synonym: purine inhibitor

receptor mediated endocytosis
type: Class
subclass of: endocytosis
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process by which cells internalize molecules by the inward budding of plasma membrane vesicles containing proteins with receptor sites specific to the molecules being internalized.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>receptor mediated endocytosis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_921
preferred name: receptor mediated endocytosis

crosslinking reagent
type: Class
subclass of: reagent
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A reagent containing ends reactive to specific functional groups on molecules for modifying and linking molecules together.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>crosslinking reagent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_922
synonym: crosslinker
synonym: crosslinking agent
preferred name: crosslinking reagent

titanium
type: Class
subclass of: element
disjoint with: erbium
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 22.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>titanium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_924
preferred name: titanium

granule
type: Class
equivalent class: Class
  intersection of: solid
  intersection of: Restriction
    on property: has quality
    some values from: granular state
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A solid which corresponds to any small grainlike particle.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>granule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C61363
code: NPO_925
preferred name: granule

heat generation in response to stimulus of infrared light
type: Class
subclass of: nanoparticle response to infrared light
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to infrared light, which involves the generation of heat.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>heat generation in response to stimulus of infrared light</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_926
preferred name: heat generation in response to stimulus of infrared light

acyl azide
type: Class
equivalent class: Restriction
  on property: has part
  some values from: acyl azide group
subclass of: acyl compound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acyl azide is an acyl compound which is characterized by the presence of acyl azide group. It has the structure R-C(=O)-[N+]#N, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>acyl azide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_927
preferred name: acyl azide
synonym: acyl azide derivative

erbium
type: Class
subclass of: element
disjoint with: scandium
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 68.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>erbium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_928
preferred name: erbium

scandium
type: Class
subclass of: element
disjoint with: ytterbium
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 21.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>scandium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_929
preferred name: scandium

ytterbium
type: Class
subclass of: element
disjoint with: krypton
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 70.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ytterbium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_932
preferred name: ytterbium

krypton
type: Class
subclass of: element
disjoint with: lanthanum
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 36.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>krypton</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_933
preferred name: krypton

chromium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: chromium
subclass of: Restriction
  on property: is integral part of
  all values from: chromium
subclass of: Restriction
  on property: atomic Number
  has value: 24
disjoint with: cobalt atom
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 24.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>chromium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_934
preferred name: chromium atom

cobalt atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 27
subclass of: Restriction
  on property: is integral part of
  all values from: cobalt
subclass of: Restriction
  on property: is integral part of
  some values from: cobalt
disjoint with: protactinium atom
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 27.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cobalt atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_935
preferred name: cobalt atom

lanthanum
type: Class
subclass of: element
disjoint with: nobelium
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 57.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>lanthanum</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_936
preferred name: lanthanum

stimulus of infrared light
type: Class
subclass of: stimulus of light
subclass of: Restriction
  on property: stimulus causes response
  some values from: nanoparticle response to infrared light
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by infrared light.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>stimulus of infrared light</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_937
preferred name: stimulus of infrared light

biocompatible
type: Class
subclass of: realizable_entity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity that inheres in a material entity and indicates that the bearer has the ability to be harmless to biological systems.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>biocompatible</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_938
preferred name: biocompatible

DNA binding agent
type: Class
equivalent class: Class
  intersection of: antineoplastic agent
  intersection of: Restriction
    on property: has function
    some values from: Class
      intersection of: binding function
      intersection of: Restriction
        on property: is realized in
        some values from: DNA binding
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: inhibitor role
    intersection of: Restriction
      on property: is realized in
      some values from: negative regulation of DNA replication
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic agent that binds to DNA to regulate mechanisms central to cellular function, including DNA replication and gene expression.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>DNA binding agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: DNA binding agent
DB xref ID: NCIT: C2842
code: NPO_939

non-covalent interaction
type: Class
equivalent class: Class
  union of: hydrophobic interaction
  union of: ionic bonding
  union of: intermolecular interaction
subclass of: chemical interaction
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical interaction which is non-covalent in nature and provides the force to hold molecules or parts of molecules together.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>non-covalent interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_940
synonym: non-covalent bonding
preferred name: non-covalent interaction

nobelium
type: Class
subclass of: element
disjoint with: selenium
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 102.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nobelium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_942
preferred name: nobelium

single-walled carbon nanotube
type: Class
subclass of: single-walled nanotube
subclass of: Restriction
  on property: has part
  some values from: carbon
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A single-walled nanotube which consists of a single graphite layer or sheet of hexagonal arrays of carbon, rolled into a seamless cylinder with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>single-walled carbon nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_943
synonym: SWCNT
preferred name: single-walled carbon nanotube

acyl halide group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: has part
  some values from: halo group
subclass of: Restriction
  on property: has part
  some values from: acyl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure R-C(=O)-X, where R denotes an organic group and X, a halogen atom. The group is characteristic of an acyl halide.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>acyl halide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_944
comment: Prefix: haloformyl- ; Suffix: -oyl halide
preferred name: acyl halide group

passive targeting
type: Class
subclass of: tumor targeting
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A physiologically-dependent process by which a material entity reaches tumor sites, cancer cells or intracellular organelles in cancer cells.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>passive targeting</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_945
preferred name: passive targeting

protactinium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: protactinium
subclass of: Restriction
  on property: is integral part of
  all values from: protactinium
subclass of: Restriction
  on property: atomic Number
  has value: 91
disjoint with: thalium atom
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 91.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>protactinium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_946
preferred name: protactinium atom

selenium
type: Class
subclass of: element
disjoint with: uranium
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 34.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>selenium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_948
preferred name: selenium

dextran-coated nanoparticle
type: Class
equivalent class: Class
  intersection of: nanoparticle
  intersection of: Restriction
    on property: has component part
    some values from: Class
      intersection of: dextran
      intersection of: Restriction
        on property: has role
        some values from: nanoparticle surface modifying role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a coating agent composed of dextran.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dextran-coated nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_949
preferred name: dextran-coated nanoparticle

aliphatic
type: Class
subclass of: organic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic quality inhering in a chemical substance due to the presence of cyclic or acyclic, saturated or unsaturated carbon compounds, but with the exclusion of aromatic quality.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>aliphatic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: Definition of aliphatic is based on the CHEBI definition for aliphatic compounds (CHEBI:33653)
code: NPO_950
preferred name: aliphatic

polarity
type: Class
subclass of: independent specific individual quality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality that inheres in a molecule or chemical bond due to the presence or absence of dipole moments.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>polarity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_951
preferred name: polarity

uranium
type: Class
subclass of: element
disjoint with: curium
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 92.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>uranium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_952
preferred name: uranium

ionizable to gain negative charge
type: Class
subclass of: ionizable
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ionizable property inhering in a chemical substance by virtue of having the ability to be ionized and gain a negative charge.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ionizable to gain negative charge</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_954
preferred name: ionizable to gain negative charge

thalium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: thallium
subclass of: Restriction
  on property: atomic Number
  has value: 81
subclass of: Restriction
  on property: is integral part of
  some values from: thallium
disjoint with: nobelium atom
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 81.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thalium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_955
preferred name: thalium atom

epoxide compound
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: epoxide group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An epoxide compound is an organic compound which is characterized by the presence of an epoxide group. It has the structure R-C1H-CH2-O1, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>epoxide compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_956
preferred name: epoxide compound
synonym: epoxide derivative

stimulus of pO2 change
type: Class
subclass of: internal stimulus for nanoparticle function
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An internal stimulus for nanoparticle function, which is caused by a change in pO2.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>stimulus of pO2 change</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_957
preferred name: stimulus of pO2 change

nobelium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 102
subclass of: Restriction
  on property: is integral part of
  some values from: nobelium
subclass of: Restriction
  on property: is integral part of
  all values from: nobelium
disjoint with: plutonium atom
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 102.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nobelium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_960
preferred name: nobelium atom

anticancer drug that induces breakage of DNA helix
type: Class
subclass of: drug directed against tumor DNA
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug directed against the DNA in a tumor cell to inhibit DNA replication.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>anticancer drug that induces breakage of DNA helix</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_961
preferred name: anticancer drug that induces breakage of DNA helix

non-polar covalent bonding
type: Class
subclass of: covalent interaction
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent bonding in which the sharing of electron pair is equal.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>non-polar covalent bonding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_962
preferred name: non-polar covalent bonding
comment: occurs for covalent bond between similar types of atoms or between atoms that have almost zero electronegativity difference.

pH-sensitive linker
type: Class
subclass of: spacer
subclass of: Restriction
  on property: has property
  some values from: pH-sensitive
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A spacer, which can be cleaved in response to a change in pH of the solution containing that spacer.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>pH-sensitive linker</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_963
preferred name: pH-sensitive linker
synonym: pH-sensitive spacer

poly(amidoamine) dendrimer
type: Class
subclass of: dendrimer
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: dendrimer repeat unit
    intersection of: carboxamide
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: primary amine group
    intersection of: dendrimer end group
subclass of: Restriction
  on property: has part
  some values from: poly(amidoamine)
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dendrimer which contains amide molecules as branches; tertiary amines as branching points and primary amine groups as the terminal or end groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>poly(amidoamine) dendrimer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_965
synonym: PAMAM dendrimer
preferred name: poly(amidoamine) dendrimer

plutonium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: plutonium
subclass of: Restriction
  on property: is integral part of
  all values from: plutonium
subclass of: Restriction
  on property: atomic Number
  has value: 94
disjoint with: erbium atom
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 94.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>plutonium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_966
preferred name: plutonium atom

erbium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  all values from: erbium
subclass of: Restriction
  on property: is integral part of
  some values from: erbium
subclass of: Restriction
  on property: atomic Number
  has value: 68
disjoint with: oxygen atom
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 68.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>erbium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_967
preferred name: erbium atom

oxygen atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 8
subclass of: Restriction
  on property: is integral part of
  some values from: oxygen
subclass of: Restriction
  on property: is integral part of
  all values from: oxygen
disjoint with: magnesium atom
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 8.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>oxygen atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_968
preferred name: oxygen atom

hydrazone group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: hydrazone
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group derived by replacing the =O of an aldehyde or a ketone group with =N-NH2 or =N-NH-R'. It has the structure -C(=N-NH2)- or -C(=N-NH-)-, and the group is characteristic of a hydrazone.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydrazone group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_969
preferred name: hydrazone group

curium
type: Class
subclass of: element
disjoint with: thulium
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 96.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>curium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_970
preferred name: curium

thulium
type: Class
subclass of: element
disjoint with: cadmium
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 69.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thulium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_972
preferred name: thulium

isotope
type: Class
subclass of: chemical entity
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material entity which is one of two or more forms of atoms - of a chemical element-that contain the same number of protons but different number of neutrons in their nuclei. Hence an isotope differs from an atom in relative atomic mass and physical properties but not in chemical properties; an isotope is a radioactive form of element.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>isotope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_973
preferred name: isotope

drug release from nanoparticle in response to pH change
type: Class
subclass of: nanoparticle response to pH change
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to pH change, which involves the release of drugs from a drug-loaded nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>drug release from nanoparticle in response to pH change</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_975
preferred name: drug release from nanoparticle in response to pH change

cadmium
type: Class
subclass of: element
disjoint with: lutetium
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 48.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cadmium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_976
preferred name: cadmium

magnesium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: is integral part of
  some values from: magnesium
subclass of: Restriction
  on property: atomic Number
  has value: 12
subclass of: Restriction
  on property: is integral part of
  all values from: magnesium
disjoint with: europium atom
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 12.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>magnesium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_977
preferred name: magnesium atom

europium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 63
subclass of: Restriction
  on property: is integral part of
  some values from: europium
subclass of: Restriction
  on property: is integral part of
  all values from: europium
disjoint with: rutherfordium atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 63.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>europium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_978
preferred name: europium atom

Group 7 Element
type: Class
equivalent class: Class
  union of: manganese
  union of: bohrium
  union of: rhenium
  union of: technetium
subclass of: group element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 7 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Group 7 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: Group 7 Element
code: NPO_979
synonym: manganese group element

rutherfordium atom
type: Class
subclass of: atom
subclass of: Restriction
  on property: atomic Number
  has value: 104
subclass of: Restriction
  on property: is integral part of
  some values from: rutherfordium
subclass of: Restriction
  on property: is integral part of
  all values from: rutherfordium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 104.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>rutherfordium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_980
preferred name: rutherfordium atom

lutetium
type: Class
subclass of: element
disjoint with: bromine
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 71.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>lutetium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_981
preferred name: lutetium

amine-reactive and sulfhydryl-reactive crosslinker
type: Class
subclass of: heterobifunctional crosslinker
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A heterobifunctional crosslinker, which has an amine-reactive group at one end and a sulfhydryl-reactive group at the other end.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>amine-reactive and sulfhydryl-reactive crosslinker</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_983
preferred name: amine-reactive and sulfhydryl-reactive crosslinker

temperature-sensitive
type: Class
subclass of: sensitivity to stimulus
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition inhering in any material entity, whose structure or function can be altered by changes in temperature.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>temperature-sensitive</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_985
preferred name: temperature-sensitive

carbamate ester group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: carbamate ester
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which contains a carboxylic ester bound to a primary or secondary or tertiary amine group. The group is characteristic of a carbamate ester compound.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carbamate ester group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_986
preferred name: carbamate ester group

disulfide linkage
type: Class
subclass of: covalent linkage
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a disulfide group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>disulfide linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_987
preferred name: disulfide linkage

thioether linkage between thiol and aziridine derivative
type: Class
subclass of: thioether linkage
subclass of: Restriction
  on property: part of
  some values from: thioether group
subclass of: Restriction
  on property: derives from
  some values from: aziridine group
subclass of: Restriction
  on property: derives from
  some values from: sulfhydryl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thioether linkage which occurs between a thiol and an aziridine derivative, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thioether linkage between thiol and aziridine derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_988
preferred name: thioether linkage between thiol and aziridine derivative

bromine
type: Class
subclass of: element
disjoint with: hafnium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 35.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>bromine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_989
preferred name: bromine

acyl iodide group
type: Class
subclass of: acyl halide group
subclass of: Restriction
  on property: has part
  some values from: iodo group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acyl halide group in which the halogen atom is an iodine atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>acyl iodide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_990
preferred name: acyl iodide group

hafnium
type: Class
subclass of: element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 72.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hafnium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_991
preferred name: hafnium

Premerged_Concepts
type: Class
code: NHC50000
preferred name: Premerged_Concepts
comment: This is in support of NCI Edit tab Merge and PreMerge function

Preretired_Concepts
type: Class
code: NHC50001
preferred name: Preretired_Concepts
comment: This is in support of the NCI Edit Tab Retired and Preretire functions

Retired_Concept_Current_Year
type: Class
subclass of: Retired_Concepts
code: NHC50003
preferred name: Retired_Concept_Current_Year
comment: This is in support of the NCI Edit Tab Retired and Preretire functions

Retired_Concepts
type: Class
code: NHC50002
preferred name: Retired_Concepts
comment: This is in support of the NCI Edit Tab Retired and Preretire functions

cysteine
type: Class
subclass of: alpha-aminoacid
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: alpha-aminoacid sidechain
    intersection of: Restriction
      on property: has property
      some values from: ionizable to gain negative charge
synonym: 2-amino-3-sulfanylpropanoic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-SH)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cysteine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:15356
synonym: Cys
code: NPO_384
preferred name: cysteine

water
type: Class
subclass of: oxygen hydride
subclass of: Restriction
  on property: has quality
  some values from: liquid state
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxygen hydride which is a liquid and has the chemical formula H2O</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>water</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:15377
code: NPO_1561
preferred name: water

glycine
type: Class
subclass of: alpha-aminoacid
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: alpha-aminoacid sidechain
    intersection of: Restriction
      on property: has quality
      some values from: aliphatic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH2-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>glycine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:15428
synonym: Gln
code: NPO_800
synonym: aminoacetic acid
preferred name: glycine

bromide
type: Class
subclass of: halide anion
subclass of: Restriction
  on property: has part
  some values from: bromine
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion of bromine.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>bromide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:15858
code: NPO_1046
preferred name: bromide

polynucleotide
type: Class
subclass of: biopolymer
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A biopolymer composed of nucleotide monomers which are covalently bonded in a long chain.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>polynucleotide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:15986
code: NPO_1000
preferred name: polynucleotide

halide anion
type: Class
subclass of: monoatomic monoanion
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion of halogen element.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>halide anion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:16042
code: NPO_1045
preferred name: halide anion

iodide
type: Class
subclass of: halide anion
subclass of: Restriction
  on property: has part
  some values from: iodine
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion of iodine.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>iodide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:16382
code: NPO_1049
preferred name: iodide

alanine
type: Class
subclass of: alpha-aminoacid
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: alpha-aminoacid sidechain
    intersection of: Restriction
      on property: has quality
      some values from: aliphatic
synonym: 2-aminopropanoic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>alanine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: Ala
DB xref ID: CHEBI:16449
code: NPO_540
preferred name: alanine

methionine
type: Class
subclass of: alpha-aminoacid
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: alpha-aminoacid sidechain
    intersection of: Restriction
      on property: has quality
      some values from: aliphatic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-CH2-S-CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>methionine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:16811
synonym: Met
code: NPO_158
preferred name: methionine

fluoride
type: Class
subclass of: halide anion
subclass of: Restriction
  on property: has part
  some values from: fluorine
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion of fluorine.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fluoride</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:17051
code: NPO_1048
preferred name: fluoride

ketone
type: Class
equivalent class: Class
  intersection of: carbonyl compound
  intersection of: Restriction
    on property: has part
    some values from: ketone group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A ketone is a carbonyl compound wherein the carbonyl group is bonded to two carbon atoms. It is characterized by the presence of a ketone group, and therefore, has the structure R-C(=O)-R', where R,R' stand for organic groups and not hydrogen atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ketone</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:17087
code: NPO_879
preferred name: ketone

phosphoramide
type: Class
equivalent class: Class
  intersection of: amide
  intersection of: Restriction
    on property: has part
    some values from: phosphoramide group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phosphoramide is an amide characterized by the presence of a phosphoramide group. It has the structure R-P(=O)-NH2, R-P(=O)-NH-R' or R-P(=O)-N(-R")-R', where R,R',R" denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>phosphoramide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:17102
code: NPO_116
preferred name: phosphoramide

aldehyde
type: Class
equivalent class: Class
  intersection of: carbonyl compound
  intersection of: Restriction
    on property: has part
    some values from: aldehyde group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aldehyde is a carbonyl compound wherein the carbonyl group is bonded to one hydrogen atom, and one organic group or another hydrogen atom. It is characterized by the presence of an aldehyde group, and has the structure R-C(=O)H, where R denotes an organic group or a hydrogen atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>aldehyde</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:17478
code: NPO_415
preferred name: aldehyde
comment: prefix: aldo- suffix: -al

glycolic acid
type: Class
subclass of: organic compound or molecule
subclass of: Restriction
  on property: has part
  some values from: hydroxyl group
subclass of: Restriction
  on property: has part
  some values from: carboxyl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound which has the formula (OH)CH2-C(OH)=O.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>glycolic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:17497
code: NPO_1558
preferred name: glycolic acid

serine
type: Class
subclass of: alpha-aminoacid
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: alpha-aminoacid sidechain
    intersection of: Restriction
      on property: has quality
      some values from: polar
synonym: 2-amino-3-hydroxypropanoic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-OH)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>serine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:17822
code: NPO_494
synonym: Ser
preferred name: serine

chloride
type: Class
subclass of: halide anion
subclass of: Restriction
  on property: has part
  some values from: chlorine
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion of chlorine.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>chloride</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:17996
code: NPO_1047
preferred name: chloride

polysaccharide
type: Class
subclass of: biopolymer
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A biopolymer which consists of large numbers of monosaccharide residues linked glycosidically.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>polysaccharide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:18154
code: NPO_912
comment: This term is commonly used only for those polysaccharides that contain more than ten monosaccharide residues.
comment: [definition source]: CHEBI
synonym: glycan
preferred name: polysaccharide

tyrosine
type: Class
subclass of: alpha-aminoacid
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: alpha-aminoacid sidechain
    intersection of: Restriction
      on property: has property
      some values from: ionizable to gain negative charge
    intersection of: Restriction
      on property: has quality
      some values from: aromatic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(Cc1ccc(O)cc1)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tyrosine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:18186
code: NPO_906
synonym: Try
preferred name: tyrosine

glutamic acid
type: Class
subclass of: alpha-aminoacid
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: alpha-aminoacid sidechain
    intersection of: Restriction
      on property: has property
      some values from: ionizable to gain negative charge
    intersection of: Restriction
      on property: has quality
      some values from: aliphatic
synonym: 2-aminopentanedioic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2CH2C(OH)=O)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>glutamic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:18237
synonym: Glu
code: NPO_974
preferred name: glutamic acid

magnesium (2+) ion
type: Class
subclass of: monoatomic dication
subclass of: Restriction
  on property: has part
  some values from: magnesium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic dication of magnesium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>magnesium (2+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:18420
code: NPO_1056
preferred name: magnesium (2+) ion

acyl group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: acyl compound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which is derived by the removal of one or more hydroxyl groups from an oxoacid. It has the structure R-C(=O)-, where R denotes an organic substituent from the oxoacid.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>acyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:22221
code: NPO_302
preferred name: acyl group
synonym: alkanoyl group

alkyl group
type: Class
subclass of: hydrocarbyl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrocarbyl group which is derived from an alkane by removal of a hydrogen atom from any carbon atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>alkyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: Alkyl group is a substituent group from alkane.
DB xref ID: CHEBI:22323
code: NPO_931
preferred name: alkyl group

anion
type: Class
subclass of: ion
subclass of: Restriction
  on property: has quality
  some values from: negative charge
disjoint with: cation
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ion which is negatively charged.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>anion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:22563
code: NPO_1030
preferred name: anion

arsenic molecular entity
type: Class
equivalent class: Class
  intersection of: pnictogen molecular entity
  intersection of: Restriction
    on property: has part
    some values from: arsenic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of arsenic.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>arsenic molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:22632
code: NPO_1094
preferred name: arsenic molecular entity

asparagine
type: Class
subclass of: alpha-aminoacid
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: alpha-aminoacid sidechain
    intersection of: Restriction
      on property: has quality
      some values from: polar
synonym: 2,4-diamino-4-oxobutanoic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2CH(NH)=O)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>asparagine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: Asn
DB xref ID: CHEBI:22653
code: NPO_452
preferred name: asparagine

aspartic acid
type: Class
subclass of: alpha-aminoacid
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: alpha-aminoacid sidechain
    intersection of: Restriction
      on property: has property
      some values from: ionizable to gain negative charge
    intersection of: Restriction
      on property: has quality
      some values from: aliphatic
synonym: 2-aminobutanedioic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2CH(OH)=O)-C(OH)=OH</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>aspartic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: Asp
DB xref ID: CHEBI:22660
code: NPO_853
preferred name: aspartic acid

bleomycin
type: Class
subclass of: glycopeptide
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: therapeutic function
    intersection of: Restriction
      on property: is realized in
      some values from: tumor angiogenesis inhibition
subclass of: Restriction
  on property: has role
  some values from: anticancer drug role
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: agent role
    intersection of: Restriction
      on property: is realized in
      some values from: DNA crosslinking
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: alkylating function
    intersection of: Restriction
      on property: is realized in
      some values from: DNA alkylation
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: binding function
    intersection of: Restriction
      on property: is realized in
      some values from: DNA binding
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: antibiotic role
    intersection of: Restriction
      on property: is realized in
      some values from: inhibition of cancer cell growth
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: therapeutic function
    intersection of: Restriction
      on property: is realized in
      some values from: antineoplastic activity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A glycopeptide, which is isolated from fungus; and with iron, it forms complexes that reduce molecular oxygen to superoxide.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>bleomycin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:22907
code: NPO_839
preferred name: bleomycin
comment: drug targeted against tumor DNA

boron molecular entity
type: Class
equivalent class: Class
  intersection of: boron group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: boron
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of boron.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>boron molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:22916
code: NPO_1104
preferred name: boron molecular entity

bromine molecular entity
type: Class
equivalent class: Class
  intersection of: halogen molecular entity
  intersection of: Restriction
    on property: has part
    some values from: bromine
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of bromine.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>bromine molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:22928
code: NPO_1089
preferred name: bromine molecular entity

cadmium molecular entity
type: Class
equivalent class: Class
  intersection of: zinc group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: cadmium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of cadmium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cadmium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:22978
code: NPO_1124
preferred name: cadmium molecular entity

carbamate ester
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: carbamate ester group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carbamate ester is an organic compound which is characterized by the presence of a carbamate ester group. It has the structure R-O-C(=O)-NH2 or R-O-C(=O)-NH-R' or R-O-C(=O)-N(-R")-R', where R, R', R" denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carbamate ester</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:23003
code: NPO_828
preferred name: carbamate ester

carbohydrate
type: Class
equivalent class: Class
  union of: polysaccharide
  union of: oligosaccharide
subclass of: organic compound or molecule
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The generic term 'carbohydrate' includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more terminal groups to carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom, an amino group, a thiol group or similar heteroatomic groups. It also includes derivatives of these compounds. The term 'sugar' is frequently applied to monosaccharides and lower oligosaccharides. Cyclitols are generally not regarded as carbohydrates.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carbohydrate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:23008
DB xref ID: MESH: D002241
DB xref ID: NCIT: C344
code: NPO_423
comment: [definition source]: CHEBI
preferred name: carbohydrate

carbonyl group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: carbonyl compound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=O)-. The group is characteristic of a carbonyl compound wherein it is attached to the remaining part of the molecule via single covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carbonyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:23019
code: NPO_750
preferred name: carbonyl group

chlorine molecular entity
type: Class
equivalent class: Class
  intersection of: halogen molecular entity
  intersection of: Restriction
    on property: has part
    some values from: chlorine
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of chlorine.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>chlorine molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:23117
code: NPO_1090
preferred name: chlorine molecular entity

chromium molecular entity
type: Class
equivalent class: Class
  intersection of: chromium group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: chromium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of chromium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>chromium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:23237
code: NPO_1126
preferred name: chromium molecular entity

molecular entity
type: Class
subclass of: chemical entity
subclass of: Restriction
  on property: has quality
  some values from: molecular structure
subclass of: Restriction
  on property: has part
  some values from: atom
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity is any molecule, ion, ion pair, radical ion, complex, conformer,etc., identifiable as a separately distinguishable entity.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:23367
code: NPO_355
preferred name: molecular entity

copper molecular entity
type: Class
equivalent class: Class
  intersection of: copper group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: copper
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of copper.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>copper molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:23377
code: NPO_1131
preferred name: copper molecular entity

diterpenoid
type: Class
subclass of: terpenoid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A terpenoid which has a C20 skeleton.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>diterpenoid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:23849
code: NPO_659
preferred name: diterpenoid

monoatomic anion
type: Class
equivalent class: Class
  intersection of: anion
  intersection of: Restriction
    on property: has quality
    some values from: monoatomic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion which consists of a single atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>monoatomic anion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:23905
code: NPO_1035
preferred name: monoatomic anion

monoatomic cation
type: Class
equivalent class: Class
  intersection of: cation
  intersection of: Restriction
    on property: has quality
    some values from: monoatomic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cation which consists of a single atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>monoatomic cation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:23906
code: NPO_1039
preferred name: monoatomic cation

fluorine molecular entity
type: Class
equivalent class: Class
  intersection of: halogen molecular entity
  intersection of: Restriction
    on property: has part
    some values from: fluorine
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of fluorine.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fluorine molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:24062
code: NPO_1091
preferred name: fluorine molecular entity

glycopeptide
type: Class
subclass of: peptide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A peptide compound in which a carbohydrate component is linked to a peptide component.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>glycopeptide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:24396
code: NPO_482
preferred name: glycopeptide

molecular structure
type: Class
subclass of: independent specific individual quality
subclass of: Restriction
  on property: quality of
  some values from: molecular entity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a molecular entity or part thereof, by virtue of its chemical composition and/or connectivity between its constituent atoms; or a complex composition of other molecular entities.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>molecular structure</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:24431
code: NPO_392
preferred name: molecular structure

group
type: Class
subclass of: fiat material part
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A group is a defined linked collection of atoms or a single atom within a molecular entity.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:24433
code: NPO_303
preferred name: group

halogen molecular entity
type: Class
equivalent class: Class
  intersection of: p-block molecular entity
  intersection of: Restriction
    on property: has part
    some values from: Group 17 Element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a halogen (Group-17) element.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>halogen molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:24471
code: NPO_1084
preferred name: halogen molecular entity

organic heterocyclic compound
type: Class
subclass of: heteroorganic compound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cyclic organic compound, which has ring members that are atoms of carbon and at least of one other element such as sulfur, oxygen or nitrogen.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>organic heterocyclic compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:24532
code: NPO_692
preferred name: organic heterocyclic compound

hydroxide
type: Class
equivalent class: Class
  intersection of: compound by chemical composition
  intersection of: Restriction
    on property: has part
    some values from: hydroxyl group
subclass of: Restriction
  on property: has quality
  some values from: heteroatomic
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A compound which contains a hydroxy group or salts containing hydroxide (OH(-)).</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydroxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:24651
code: NPO_1145
preferred name: hydroxide

imine
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: imine group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imine is an organic compound which is characterized by the presence of a carbon-nitrogen double bond, and has the structure R-C(=N-R")-R', where at least one of R,R',R" is a hydrocarbyl group while the remaining being hydrogen atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>imine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:24783
code: NPO_734
preferred name: imine

inorganic anion
type: Class
equivalent class: Class
  intersection of: anion
  intersection of: Restriction
    on property: has quality
    some values from: inorganic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion which is inorganic.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>inorganic anion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:24834
code: NPO_1036
preferred name: inorganic anion

inorganic molecular entity
type: Class
equivalent class: Class
  intersection of: molecular entity
  intersection of: Restriction
    on property: has quality
    some values from: inorganic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains no carbon.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>inorganic molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:24835
code: NPO_1027
preferred name: inorganic molecular entity

iodine molecular entity
type: Class
equivalent class: Class
  intersection of: halogen molecular entity
  intersection of: Restriction
    on property: has part
    some values from: iodine
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of iodine.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>iodine molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:24860
code: NPO_1092
preferred name: iodine molecular entity

salt
type: Class
subclass of: inorganic compound or molecule
subclass of: Restriction
  on property: has part
  some values from: anion
subclass of: Restriction
  on property: has part
  some values from: cation
subclass of: Restriction
  on property: has quality
  some values from: heteroatomic
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical compound which is formed by ionic interactions between cations and anions.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>salt</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:24866
code: NPO_1146
synonym: ionic compound
preferred name: salt

monoatomic ion
type: Class
equivalent class: Class
  intersection of: ion
  intersection of: Restriction
    on property: has quality
    some values from: monoatomic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ion which consists of a single atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>monoatomic ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:24867
code: NPO_1034
preferred name: monoatomic ion

ion
type: Class
subclass of: chemical entity
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A chemical entity which carries a net electric charge.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:24870
code: NPO_546
comment: [definition source]: ChEBI
preferred name: ion

iron molecular entity
type: Class
equivalent class: Class
  intersection of: iron group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: iron
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of iron.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>iron molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:24873
code: NPO_1134
preferred name: iron molecular entity

isoleucine
type: Class
subclass of: alpha-aminoacid
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: alpha-aminoacid sidechain
    intersection of: Restriction
      on property: has quality
      some values from: aliphatic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH(CH3)-CH2-CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>isoleucine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:24898
synonym: Ile
code: NPO_902
preferred name: isoleucine

isoprenoid
type: Class
subclass of: lipid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any lipid which is formally derived from isoprene (2-methylbuta-1,3-diene), the skeleton of which can generally be discerned in repeated occurrence in the molecule. The skeleton of isoprenoids may differ from strict additivity of isoprene units by loss or shift of a fragment, commonly a methyl group. The class includes both hydrocarbons and oxygenated derivatives.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>isoprenoid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:24913
code: NPO_387
preferred name: isoprenoid

leucine
type: Class
subclass of: alpha-aminoacid
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: alpha-aminoacid sidechain
    intersection of: Restriction
      on property: has quality
      some values from: aliphatic
synonym: 2-amino-4-methylpentanoic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-CH(CH3)-CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>leucine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:25017
synonym: Leu
code: NPO_285
preferred name: leucine

lysine
type: Class
subclass of: alpha-aminoacid
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: alpha-aminoacid sidechain
    intersection of: Restriction
      on property: has property
      some values from: ionizable to gain positive charge
    intersection of: Restriction
      on property: has quality
      some values from: aliphatic
synonym: 2,6-diaminohexanoic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-CH2-CH2-CH2-NH2)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>lysine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:25094
synonym: Lys
code: NPO_265
preferred name: lysine

manganese molecular entity
type: Class
equivalent class: Class
  intersection of: manganese group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: manganese
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of manganese.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>manganese molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:25154
code: NPO_1136
preferred name: manganese molecular entity

mercury molecular entity
type: Class
equivalent class: Class
  intersection of: zinc group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: mercury
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of mercury.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>mercury molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:25196
code: NPO_1125
preferred name: mercury molecular entity

metal cation
type: Class
equivalent class: Class
  intersection of: monoatomic cation
  intersection of: Restriction
    on property: has part
    some values from: metal
subclass of: Restriction
  on property: has quality
  some values from: inorganic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic cation of a metal.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>metal cation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:25213
code: NPO_1052
preferred name: metal cation

mitomycin
type: Class
subclass of: quinone
subclass of: Restriction
  on property: has role
  some values from: anticancer drug role
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: alkylating function
    intersection of: Restriction
      on property: is realized in
      some values from: DNA alkylation
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: antibiotic role
    intersection of: Restriction
      on property: is realized in
      some values from: inhibition of cancer cell growth
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: binding function
    intersection of: Restriction
      on property: is realized in
      some values from: DNA binding
subclass of: Restriction
  on property: has part
  some values from: carbamate ester group
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: therapeutic function
    intersection of: Restriction
      on property: is realized in
      some values from: antineoplastic activity
subclass of: Restriction
  on property: has part
  some values from: aziridine group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quinone which is an aziridine-containing compound isolated from Streptomyces lavendulae.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>mitomycin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:25357
code: NPO_352
preferred name: mitomycin

homoatomic molecule
type: Class
equivalent class: Class
  intersection of: molecular entity
  intersection of: Restriction
    on property: has quality
    some values from: homoatomic
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A molecule which consists of atoms of the same element.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>homoatomic molecule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:25362
code: NPO_1028
preferred name: homoatomic molecule

molybdenum molecular entity
type: Class
equivalent class: Class
  intersection of: chromium group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: molybdenum
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of molybdenum.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>molybdenum molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:25370
code: NPO_1127
preferred name: molybdenum molecular entity

monoatomic monocation
type: Class
subclass of: monoatomic cation
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic cation which has ionic charge 1+.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>monoatomic monocation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:25414
code: NPO_1054
preferred name: monoatomic monocation

monoatomic polycation
type: Class
subclass of: monoatomic cation
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic cation which has ionic charge greater than 2+.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>monoatomic polycation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:25430
code: NPO_1063
preferred name: monoatomic polycation

oligosaccharide
type: Class
subclass of: carbohydrate
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A compound in which monosaccharide units are joined by glycosidic linkages. The term is commonly used to refer to a defined structure as opposed to a polymer of unspecified length or a homologous mixture. When the linkages are of other types the compounds are regarded as oligosaccharide analogues.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>oligosaccharide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:25679
code: NPO_680
comment: [definition source]: CHEBI
preferred name: oligosaccharide

organic anion
type: Class
equivalent class: Class
  intersection of: anion
  intersection of: Restriction
    on property: has quality
    some values from: organic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion which is organic.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>organic anion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:25696
code: NPO_1037
preferred name: organic anion

organic cation
type: Class
equivalent class: Class
  intersection of: cation
  intersection of: Restriction
    on property: has quality
    some values from: organic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cation which is organic.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>organic cation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:25697
code: NPO_1041
preferred name: organic cation

ether
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: ether group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ether is an organic compound in which an oxygen atom is covalently bound to two carbon atoms. It has the structure R-O-R', where R, R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ether</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:25698
code: NPO_230
preferred name: ether

organic ion
type: Class
equivalent class: Class
  intersection of: ion
  intersection of: Restriction
    on property: has quality
    some values from: organic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ion which is organic.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>organic ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:25699
code: NPO_1031
preferred name: organic ion

oxide
type: Class
subclass of: inorganic compound or molecule
subclass of: Restriction
  on property: has quality
  some values from: heteroatomic
subclass of: Restriction
  on property: has part
  some values from: oxygen
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A chemical compound of oxygen with other chemical elements.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:25741
code: NPO_1147
preferred name: oxide

oxygen molecular entity
type: Class
equivalent class: Class
  intersection of: chalogen molecular entity
  intersection of: Restriction
    on property: has part
    some values from: oxygen
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of oxygen.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>oxygen molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:25806
code: NPO_1099
preferred name: oxygen molecular entity

phosphorus molecular entity
type: Class
equivalent class: Class
  intersection of: pnictogen molecular entity
  intersection of: Restriction
    on property: has part
    some values from: phosphorus
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of phosphorus.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>phosphorus molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:26082
code: NPO_1095
preferred name: phosphorus molecular entity

polyketide
type: Class
subclass of: ketone
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A ketone which is a natural compound containing alternating carbonyl and methylene groups ('?-polyketones'), biogenetically derived from repeated condensation of acetyl coenzyme A (via malonyl coenzyme A); or another compound derived from it by further condensations.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>polyketide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:26188
code: NPO_789
preferred name: polyketide

amidine
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: amidine group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amidine is an organic compound which is derived from an oxoacid RnE(=O)OH by replacing the hydroxyl group by an amino group and the oxo group by =NR. R stands for a hydrogen atom or organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>amidine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:2634
code: NPO_309
preferred name: amidine

pteridine compound
type: Class
subclass of: organic heterobicyclic compound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic heterobicyclic compound which is composed partly or wholly of a pteridine ring system (a pyrimidine ring fused with a pyrazine ring).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>pteridine compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:26373
code: NPO_900
preferred name: pteridine compound

pterin
type: Class
subclass of: pterin compound
subclass of: Restriction
  on property: has part
  some values from: primary amine group
subclass of: Restriction
  on property: has part
  some values from: hydroxyl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A pterin compound which is wholly composed of a pteridine ring system, in which the pyrimidine ring has a carbonyl oxygen and an amino group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>pterin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:26374
code: NPO_550
preferred name: pterin

pterin compound
type: Class
subclass of: pteridine compound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A pteridine compound which is wholly or partly composed of a pteridine ring system in which the pyrimidine ring has a carbonyl oxygen and an amino group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>pterin compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:26375
code: NPO_693
preferred name: pterin compound

selenium molecular entity
type: Class
equivalent class: Class
  intersection of: chalogen molecular entity
  intersection of: Restriction
    on property: has part
    some values from: selenium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of selenium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>selenium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:26628
code: NPO_1100
preferred name: selenium molecular entity

silicon molecular entity
type: Class
equivalent class: Class
  intersection of: carbon group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: silicon
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of silicon.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>silicon molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:26677
code: NPO_1109
preferred name: silicon molecular entity

sulfur molecular entity
type: Class
equivalent class: Class
  intersection of: chalogen molecular entity
  intersection of: Restriction
    on property: has part
    some values from: sulfur
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of sulfur.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>sulfur molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:26835
code: NPO_1101
preferred name: sulfur molecular entity

technetium molecular entity
type: Class
equivalent class: Class
  intersection of: manganese group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: technetium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of technetium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>technetium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:26865
code: NPO_1137
preferred name: technetium molecular entity

terpenoid
type: Class
subclass of: isoprenoid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any natural product and related compound formally derived from isoprene units. They may contain oxygen in various functional groups. This class is subdivided according to the number of carbon atoms in the same manner as are terpenes. The skeleton of terpenoids may differ from strict additivity of isoprene units by the loss or shift of a fragment, generally a methyl group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>terpenoid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:26873
code: NPO_381
preferred name: terpenoid

monoatomic tetracation
type: Class
subclass of: monoatomic polycation
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic polycation which has ionic charge 4+.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>monoatomic tetracation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:26937
code: NPO_1065
preferred name: monoatomic tetracation

threonine
type: Class
subclass of: alpha-aminoacid
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: alpha-aminoacid sidechain
    intersection of: Restriction
      on property: has quality
      some values from: polar
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH(OH)-CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>threonine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:26986
code: NPO_913
synonym: Thr
preferred name: threonine

tin molecular entity
type: Class
equivalent class: Class
  intersection of: carbon group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: tin
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of tin.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tin molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:27008
code: NPO_1110
preferred name: tin molecular entity

monoatomic trication
type: Class
subclass of: monoatomic polycation
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic polycation which has ionic charge 3+.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>monoatomic trication</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:27153
code: NPO_1064
preferred name: monoatomic trication

organic heterobicyclic compound
type: Class
subclass of: organic heterocyclic compound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic heterocyclic compound, which has two rings.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>organic heterobicyclic compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:27171
code: NPO_454
preferred name: organic heterobicyclic compound

valine
type: Class
subclass of: alpha-aminoacid
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: alpha-aminoacid sidechain
    intersection of: Restriction
      on property: has quality
      some values from: aliphatic
synonym: 2-amino-3-methylbutanoic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2(CH3)-CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>valine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:27266
code: NPO_964
synonym: Val
preferred name: valine

vanadium molecular entity
type: Class
equivalent class: Class
  intersection of: vanadium group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: vanadium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of vanadium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>vanadium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:27275
code: NPO_1144
preferred name: vanadium molecular entity

zinc molecular entity
type: Class
equivalent class: Class
  intersection of: zinc group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: zinc
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of zinc.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>zinc molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:27364
code: NPO_1123
preferred name: zinc molecular entity

folic acid
type: Class
subclass of: pterin compound
subclass of: Restriction
  on property: has part
  some values from: pterin
subclass of: Restriction
  on property: has part
  some values from: carboxyl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A pterin compound which contains para-aminobenzoic acid and L-glutamate unit conjugated with the pterin structure.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>folic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:27470
code: NPO_422
preferred name: folic acid

histidine
type: Class
subclass of: alpha-aminoacid
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: alpha-aminoacid sidechain
    intersection of: Restriction
      on property: has property
      some values from: ionizable to gain positive charge
synonym: 2-amino-3-(1H-imidazol-4-yl)propanoic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2c1c[nH]cn1)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>histidine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:27570
synonym: His
code: NPO_329
preferred name: histidine

pteridine
type: Class
subclass of: pteridine compound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A pteridine compound in which a pyrimidine ring is fused with a pyrazine ring. It has the structure c1cnc2ncncc2n1.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>pteridine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:27601
code: NPO_289
preferred name: pteridine

tryptophan
type: Class
subclass of: alpha-aminoacid
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: alpha-aminoacid sidechain
    intersection of: Restriction
      on property: has quality
      some values from: aromatic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(Cc1c[nH]c2ccccc12)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tryptophan</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:27897
code: NPO_783
synonym: Trp
preferred name: tryptophan

cisplatin
type: Class
subclass of: platinum coordination compound
subclass of: Restriction
  on property: has role
  some values from: anticancer drug role
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: therapeutic function
    intersection of: Restriction
      on property: is realized in
      some values from: antineoplastic activity
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: agent role
    intersection of: Restriction
      on property: is realized in
      some values from: DNA crosslinking
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: binding function
    intersection of: Restriction
      on property: is realized in
      some values from: DNA binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A platinum compound in which the platinum atom is complexed with two ammonia groups and two chlorine atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cisplatin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:27899
code: NPO_608
comment: anticancer drug that induces breakage of DNA helix
preferred name: cisplatin

phenylalanine
type: Class
subclass of: alpha-aminoacid
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: alpha-aminoacid sidechain
    intersection of: Restriction
      on property: has quality
      some values from: aromatic
synonym: 2-amino-3-phenylpropanoic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-c1ccccc1)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>phenylalanine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:28044
code: NPO_139
synonym: Phe
preferred name: phenylalanine

glutamine
type: Class
subclass of: alpha-aminoacid
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: alpha-aminoacid sidechain
    intersection of: Restriction
      on property: has quality
      some values from: polar
synonym: 2,5-diamino-5-oxopentanoic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2CH2C(NH2)=O)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>glutamine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:28300
code: NPO_930
preferred name: glutamine

lactic acid
type: Class
subclass of: organic compound or molecule
subclass of: Restriction
  on property: has part
  some values from: carboxyl group
subclass of: Restriction
  on property: has part
  some values from: hydroxyl group
synonym: 2-hydroxypropanoic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound which has the formula CH3CH(OH)C(OH)=O.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>lactic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:28358
code: NPO_1557
synonym: alpha-hydroxypropanoic acid
preferred name: lactic acid

doxorubicin
type: Class
subclass of: anthracycline
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: binding function
    intersection of: Restriction
      on property: is realized in
      some values from: DNA binding
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: antibiotic role
    intersection of: Restriction
      on property: is realized in
      some values from: inhibition of cancer cell growth
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: DNA intercalator role
    intersection of: Restriction
      on property: is realized in
      some values from: DNA intercalation
subclass of: Restriction
  on property: has role
  some values from: anticancer drug role
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: therapeutic function
    intersection of: Restriction
      on property: is realized in
      some values from: antineoplastic activity
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: inhibitor role
    intersection of: Restriction
      on property: is realized in
      some values from: inhibition of DNA topoisomerase type II activity
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: regulator role
    intersection of: Restriction
      on property: is realized in
      some values from: regulation of DNA-dependent transcription
synonym: 14-hydroxydaunorubicine
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anthracycline which is (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-?-L-lyxo-hexopyranoside. It has a parent hydride, tetracene, and has substructures that classify it as a deoxy hexoside, and a quinone.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>doxorubicin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:28748
code: NPO_788
synonym: adriamycin
comment: anticancer drug that inhibits protein activity related to DNA synthesis
preferred name: doxorubicin

chlorambucil
type: Class
subclass of: nitrogen mustard
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: therapeutic function
    intersection of: Restriction
      on property: is realized in
      some values from: antineoplastic activity
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: carbon atom
    intersection of: Restriction
      on property: has single bond with
      some values from: chlorine atom
    intersection of: Restriction
      on property: has single bond with
      cardinality: 1
subclass of: Restriction
  on property: has role
  some values from: anticancer drug role
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: alkylating function
    intersection of: Restriction
      on property: is realized in
      some values from: DNA alkylation
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: binding function
    intersection of: Restriction
      on property: is realized in
      some values from: DNA binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of nitrogen mustard and an organochlorine compound.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>chlorambucil</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:28830
code: NPO_346
comment: anticancer drug that induces breakage of DNA helix
preferred name: chlorambucil

arginine
type: Class
subclass of: alpha-aminoacid
subclass of: Restriction
  on property: has part
  some values from: Class
    intersection of: alpha-aminoacid sidechain
    intersection of: Restriction
      on property: has property
      some values from: ionizable to gain positive charge
    intersection of: Restriction
      on property: has quality
      some values from: aliphatic
synonym: 2-amino-5-(carbamimidamido)pentanoic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-CH2-CH2-NH-C(NH2)=NH)-C(OH)=OH</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>arginine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: Arg
DB xref ID: CHEBI:29016
code: NPO_875
preferred name: arginine

iron (2+) ion
type: Class
subclass of: monoatomic dication
subclass of: Restriction
  on property: has part
  some values from: iron
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic dication of iron.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>iron (2+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:29033
code: NPO_1057
preferred name: iron (2+) ion

iron (3+) ion
type: Class
subclass of: monoatomic trication
subclass of: Restriction
  on property: has part
  some values from: iron
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic trication of iron.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>iron (3+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:29034
code: NPO_1069
preferred name: iron (3+) ion

zinc (2+) ion
type: Class
subclass of: monoatomic dication
subclass of: Restriction
  on property: has part
  some values from: zinc
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic dication of zinc.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>zinc (2+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:29105
code: NPO_1053
preferred name: zinc (2+) ion

thiol
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: sulfhydryl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thiol is an organic compound which is characterized by the presence of a sulfhydryl group. It has the structure R-SH, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thiol</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:29256
code: NPO_465
synonym: mercaptan
synonym: sulfhydryl compound
preferred name: thiol

disulfanedyl group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: organic disulfide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -S-S-. The group is characteristic of an organic disulfide molecule wherein it is attached to organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>disulfanedyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:29826
code: NPO_884
preferred name: disulfanedyl group

sulfhydryl group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: thiol
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -SH. The group is characteristic of a thiol molecule wherein it is attached to an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>sulfhydryl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:29917
comment: It is a substituent group from hydrogen sulfide.
code: NPO_910
preferred name: sulfhydryl group
synonym: thiol group

diazo group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: diazo compound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which is a substituent group from diazene, and has the structure =[N+]=[N-]. The group is characteristic of a diazo compound wherein it is attached to an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>diazo group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:30105
code: NPO_462
preferred name: diazo group

monoatomic dication
type: Class
subclass of: monoatomic cation
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic cation which has ionic charge 2+.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>monoatomic dication</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:30412
code: NPO_1055
preferred name: monoatomic dication

astatide
type: Class
subclass of: halide anion
subclass of: Restriction
  on property: has part
  some values from: astatine
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion of astatine.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>astatide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:30417
code: NPO_1050
preferred name: astatide

molybdenum (5+) ion
type: Class
subclass of: monoatomic pentacation
subclass of: Restriction
  on property: has part
  some values from: molybdenum
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic pentacation of molybdenum.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>molybdenum (5+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:30511
code: NPO_1073
preferred name: molybdenum (5+) ion

silicon dioxide
type: Class
subclass of: silicon oxide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of silicon in which a silicon atom covalently bonded (double bond) with two oxygen atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>silicon dioxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:30563
code: NPO_1372
synonym: silica
preferred name: silicon dioxide

silicon (4+) ion
type: Class
subclass of: monoatomic tetracation
subclass of: Restriction
  on property: has part
  some values from: silicon
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic tetracation of silicon.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>silicon (4+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:30584
code: NPO_1070
preferred name: silicon (4+) ion

alcohol
type: Class
subclass of: organic hydroxy compound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alcohol is an organic hydroxy compound in which a hydroxyl group is attached to a saturated carbon atom. It has the general structure OH-C-([*])([*])[*].</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>alcohol</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:30879
code: NPO_624
preferred name: alcohol

carboplatin
type: Class
subclass of: platinum coordination compound
subclass of: Restriction
  on property: has role
  some values from: anticancer drug role
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: binding function
    intersection of: Restriction
      on property: is realized in
      some values from: DNA binding
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: therapeutic function
    intersection of: Restriction
      on property: is realized in
      some values from: antineoplastic activity
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: agent role
    intersection of: Restriction
      on property: is realized in
      some values from: DNA crosslinking
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A platinum compound in which the platinum atom is complexed with two ammonia groups and a cyclobutane-dicarboxyl residue.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carboplatin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:31355
DB xref ID: NCIT: C1282
code: NPO_603
comment: anticancer drug that induces breakage of DNA helix
preferred name: carboplatin

oxaliplatin
type: Class
subclass of: platinum coordination compound
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: therapeutic function
    intersection of: Restriction
      on property: is realized in
      some values from: antineoplastic activity
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: binding function
    intersection of: Restriction
      on property: is realized in
      some values from: DNA binding
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: agent role
    intersection of: Restriction
      on property: is realized in
      some values from: DNA crosslinking
subclass of: Restriction
  on property: has role
  some values from: anticancer drug role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A platinum compound in which the platinum atom is complexed with 1,2-diaminocyclohexane (DACH) and with an oxalate bidentate ligand.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>oxaliplatin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:31941
DB xref ID: NCIT:C1181
code: NPO_749
comment: anticancer drug that induces breakage of DNA helix
preferred name: oxaliplatin

secondary amine
type: Class
equivalent class: Class
  intersection of: amine
  intersection of: Restriction
    on property: has part
    some values from: secondary amine group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A secondary amine is an amine which is formally derived from ammonia by replacing two hydrogen atoms by hydrocarbyl groups, and it is characterized by the presence of a secondary amine group. It has the structure R-NH-R', where R,R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>secondary amine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:32863
code: NPO_805
preferred name: secondary amine

tertiary amine
type: Class
equivalent class: Class
  intersection of: amine
  intersection of: Restriction
    on property: has part
    some values from: tertiary amine group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A tertiary amine is an amine which is formally derived from ammonia by replacing three hydrogen atoms by hydrocarbyl groups, and it is characterized by the presence of a tertiary amine group. It has the structure R-N(-R")-R', where R,R' and R" denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tertiary amine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:32876
code: NPO_832
preferred name: tertiary amine

primary amine
type: Class
equivalent class: Class
  intersection of: amine
  intersection of: Restriction
    on property: has part
    some values from: primary amine group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A primary amine is an amine which is formally derived from ammonia by replacing one hydrogen atom by a hydrocarbyl group, and it is characterized by the presence of a primary amine group. It has the structure R-NH2, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>primary amine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:32877
code: NPO_947
preferred name: primary amine

amine
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: amine group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amine is an organic compound which is formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups, and it is thus characterized by the presence of a primary or secondary or tertiary amine groups. It has the structure R-NH2 or R-NH-R' or R-N(-R")-R', where R, R' and R" denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>amine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:32952
code: NPO_143
preferred name: amine

amide
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: amide group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide is an organic compound formally derived from an oxoacid by replacing an acidic hydroxyl group of the oxoacid by an amino or substituted amino group. It is characterized by the presence of an "amide group."</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>amide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:32988
code: NPO_769
preferred name: amide

vanadium 5(+) ion
type: Class
subclass of: monoatomic pentacation
subclass of: Restriction
  on property: has part
  some values from: vanadium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic pentacation of vanadium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>vanadium 5(+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33003
code: NPO_1072
preferred name: vanadium 5(+) ion

monoatomic entity
type: Class
equivalent class: Class
  intersection of: molecular entity
  intersection of: Restriction
    on property: has quality
    some values from: monoatomic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which consists of a single atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>monoatomic entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33238
code: NPO_1026
preferred name: monoatomic entity

coordination compound
type: Class
subclass of: compound by chemical composition
subclass of: Restriction
  on property: has quality
  some values from: heteroatomic
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A compound which consists of a central atom (usually metallic) to which is attached a surrounding array of other groups of atoms.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>coordination compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33240
code: NPO_1139
preferred name: coordination compound

organic functional class
type: Class
equivalent class: Class
  intersection of: organic compound or molecule
  intersection of: Restriction
    on property: has part
    some values from: functional group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound or molecule which is characterized by the presence of a functional group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>organic functional class</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33244
code: NPO_202
preferred name: organic functional class

inorganic group
type: Class
equivalent class: Class
  intersection of: group
  intersection of: Restriction
    on property: has quality
    some values from: inorganic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any substituent group which does not contain carbon.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>inorganic group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33246
code: NPO_1567
preferred name: inorganic group

hydrocarbyl group
type: Class
subclass of: group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrocarbyl group is a univalent substituent group formed by removing a hydrogen atom from a hydrocarbon.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydrocarbyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33248
code: NPO_559
preferred name: hydrocarbyl group

homoatomic molecular entity
type: Class
equivalent class: Class
  intersection of: polyatomic entity
  intersection of: Restriction
    on property: has quality
    some values from: homoatomic
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A polyatomic entity which consists of a single element.</ncicp:def-definition><ncicp:Definition_Review_Date>111020</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>homoatomic molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1025
preferred name: homoatomic molecular entity

polyatomic anion
type: Class
equivalent class: Class
  intersection of: anion
  intersection of: Restriction
    on property: has quality
    some values from: polyatomic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion which consists of more than one atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>polyatomic anion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33273
code: NPO_1038
preferred name: polyatomic anion

heteroorganic compound
type: Class
subclass of: organic compound or molecule
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A heteroorganic compound is an organic compound in which carbon atoms or organic groups are bonded directly to one or more heteroatoms.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>heteroorganic compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33285
code: NPO_293
preferred name: heteroorganic compound
synonym: heteroorganic entity
synonym: heteroorganic molecule

alkali metal molecular entity
type: Class
equivalent class: Class
  intersection of: s-block molecular entity
  intersection of: Restriction
    on property: has part
    some values from: alkali metal
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of an alkali metal.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>alkali metal molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33296
code: NPO_1081
preferred name: alkali metal molecular entity

alkaline earth molecular entity
type: Class
equivalent class: Class
  intersection of: s-block molecular entity
  intersection of: Restriction
    on property: has part
    some values from: alkali earth metal
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of an alkaline earth metal.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>alkaline earth molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33299
code: NPO_1080
preferred name: alkaline earth molecular entity

pnictogen molecular entity
type: Class
equivalent class: Class
  intersection of: p-block molecular entity
  intersection of: Restriction
    on property: has part
    some values from: Group 15 Element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a Group-15 element.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>pnictogen molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33302
code: NPO_1085
preferred name: pnictogen molecular entity

chalogen molecular entity
type: Class
equivalent class: Class
  intersection of: p-block molecular entity
  intersection of: Restriction
    on property: has part
    some values from: Group 16 Element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a Group-16 element.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>chalogen molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33304
code: NPO_1086
preferred name: chalogen molecular entity

tellurium molecular entity
type: Class
equivalent class: Class
  intersection of: chalogen molecular entity
  intersection of: Restriction
    on property: has part
    some values from: tellurium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of tellurium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tellurium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33305
code: NPO_1102
preferred name: tellurium molecular entity

carboxylic ester
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: carboxylic ester group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carboxylic ester is an organic compound which is characterized by the presence of an carboxylic ester group. It has the structure R-C(=O)-O-R', where R,R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carboxylic ester</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33308
code: NPO_790
preferred name: carboxylic ester

silicon oxide
type: Class
subclass of: oxide
subclass of: Restriction
  on property: has part
  some values from: silicon
subclass of: Restriction
  on property: has quality
  some values from: inorganic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of silicon.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>silicon oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33327
code: NPO_1371
preferred name: silicon oxide

aryl group
type: Class
subclass of: hydrocarbyl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrocarbyl group which is derived from an arene by removal of a hydrogen atom from a ring carbon atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>aryl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33338
code: NPO_826
preferred name: aryl group

monoatomic pentacation
type: Class
subclass of: monoatomic polycation
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic polycation which has ionic charge 5+.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>monoatomic pentacation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33422
code: NPO_1066
preferred name: monoatomic pentacation

monoatomic hexacation
type: Class
subclass of: monoatomic polycation
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic polycation which has ionic charge 6+.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>monoatomic hexacation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33423
code: NPO_1067
preferred name: monoatomic hexacation

monoatomic monoanion
type: Class
subclass of: monoatomic anion
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic anion which has ionic charge 1-.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>monoatomic monoanion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33429
code: NPO_1043
preferred name: monoatomic monoanion

rubidide
type: Class
subclass of: monoatomic monoanion
subclass of: Restriction
  on property: has part
  some values from: rubidium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic monanion of rubidide.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>rubidide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33496
code: NPO_1051
preferred name: rubidide

alkali metal cation
type: Class
equivalent class: Class
  intersection of: metal cation
  intersection of: Restriction
    on property: has part
    some values from: alkali metal
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic cation of alkali metal.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>alkali metal cation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33504
code: NPO_1076
preferred name: alkali metal cation

alkaline earth metal cation
type: Class
equivalent class: Class
  intersection of: metal cation
  intersection of: Restriction
    on property: has part
    some values from: alkali earth metal
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monatomic cation of an alkaline earth metal.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>alkaline earth metal cation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33513
code: NPO_1077
preferred name: alkaline earth metal cation

carboxylic acid
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: carboxyl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carboxylic acid is an organic acid compound which is characterized by the presence of a carboxyl group. It has the structure R-C(=O)-OH, where R denotes an organic group or a hydrogen atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carboxylic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33575
code: NPO_574
synonym: carboxyl compound
preferred name: carboxylic acid
comment: prefix: Carboxy- suffix: -oic acid

boron group molecular entity
type: Class
equivalent class: Class
  intersection of: p-block molecular entity
  intersection of: Restriction
    on property: has part
    some values from: Group 13 Element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a Group-13 element.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>boron group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33581
code: NPO_1087
preferred name: boron group molecular entity

carbon group molecular entity
type: Class
equivalent class: Class
  intersection of: p-block molecular entity
  intersection of: Restriction
    on property: has part
    some values from: Group 14 Element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a Group-14 element.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carbon group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33582
code: NPO_1088
preferred name: carbon group molecular entity

noble gas molecular entity
type: Class
equivalent class: Class
  intersection of: molecular entity
  intersection of: Restriction
    on property: has part
    some values from: noble gas
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a noble gas.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>noble gas molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33583
code: NPO_1079
synonym: noble gas compound
preferred name: noble gas molecular entity

germanium molecular entity
type: Class
equivalent class: Class
  intersection of: carbon group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: germanium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of germanium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>germanium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33584
code: NPO_1111
preferred name: germanium molecular entity

lead molecular entity
type: Class
equivalent class: Class
  intersection of: carbon group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: lead
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of lead.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>lead molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33585
code: NPO_1112
preferred name: lead molecular entity

aluminum molecular entity
type: Class
equivalent class: Class
  intersection of: boron group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: aluminium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of aluminum.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>aluminum molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33620
code: NPO_1105
preferred name: aluminum molecular entity

zinc group molecular entity
type: Class
equivalent class: Class
  intersection of: d-block molecular entity
  intersection of: Restriction
    on property: has part
    some values from: Group 12 Element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a zinc group (Group-12) element.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>zinc group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33673
code: NPO_1114
preferred name: zinc group molecular entity

s-block molecular entity
type: Class
equivalent class: Class
  intersection of: molecular entity
  intersection of: Restriction
    on property: has part
    some values from: s-block element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a s-block element.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>s-block molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33674
code: NPO_1082
preferred name: s-block molecular entity

p-block molecular entity
type: Class
equivalent class: Class
  intersection of: molecular entity
  intersection of: Restriction
    on property: has part
    some values from: p-block element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a p-block element.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>p-block molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33675
code: NPO_1078
preferred name: p-block molecular entity

d-block molecular entity
type: Class
equivalent class: Class
  intersection of: molecular entity
  intersection of: Restriction
    on property: has part
    some values from: d-block element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a d-block element.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>d-block molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33676
code: NPO_1083
preferred name: d-block molecular entity

hydride
type: Class
equivalent class: Class
  intersection of: compound by chemical composition
  intersection of: Restriction
    on property: has part
    some values from: hydrogen
subclass of: Restriction
  on property: has quality
  some values from: heteroatomic
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A compound of hydrogen with other chemical elements.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydride</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33692
code: NPO_1148
preferred name: hydride

oxygen hydride
type: Class
equivalent class: Class
  intersection of: hydride
  intersection of: Restriction
    on property: has part
    some values from: oxygen atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydride containing one or more oxygen atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>oxygen hydride</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33693
code: NPO_1560
preferred name: oxygen hydride

biopolymer
type: Class
subclass of: polymer
subclass of: Restriction
  on property: has property
  some values from: biocompatible
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polymer formed by living organisms.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>biopolymer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33694
DB xref ID: MESH: D001704
code: NPO_882
synonym: biomacromolecule
preferred name: biopolymer

nucleic acid
type: Class
subclass of: polynucleotide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polynucleotide which is present in living cells.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nucleic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33696
code: NPO_1001
preferred name: nucleic acid

ribonucleic acid
type: Class
subclass of: nucleic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nucleic acid which is a derivative of DNA having ribose in place of deoxyribose, and uracil in place of thymine.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ribonucleic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33697
code: NPO_1003
synonym: RNA
preferred name: ribonucleic acid

polyatomic cation
type: Class
equivalent class: Class
  intersection of: cation
  intersection of: Restriction
    on property: has quality
    some values from: polyatomic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cation which consists of more than one atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>polyatomic cation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33702
code: NPO_1040
preferred name: polyatomic cation

alpha-aminoacid
type: Class
subclass of: aminoacid
subclass of: Restriction
  on property: has part
  some values from: alpha-aminoacid sidechain
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aminoacid in which a primary amine group and a carboxyl group are attached to the same carbon atom, which is called the alpha?carbon..</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>alpha-aminoacid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33704
code: NPO_632
preferred name: alpha-aminoacid

aminoacid
type: Class
subclass of: carboxylic acid
subclass of: Restriction
  on property: has part
  some values from: primary amine group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carboxylic acid containing one or more amine groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>aminoacid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33709
code: NPO_506
preferred name: aminoacid

chromium group molecular entity
type: Class
equivalent class: Class
  intersection of: d-block molecular entity
  intersection of: Restriction
    on property: has part
    some values from: Group 6 Element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a chromium group (Group-6) element.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>chromium group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33741
code: NPO_1115
preferred name: chromium group molecular entity

tungsten molecular entity
type: Class
equivalent class: Class
  intersection of: chromium group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: tungsten
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of tungsten.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tungsten molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33742
code: NPO_1128
preferred name: tungsten molecular entity

manganese group molecular entity
type: Class
equivalent class: Class
  intersection of: d-block molecular entity
  intersection of: Restriction
    on property: has part
    some values from: Group 7 Element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a manganese group (Group-7) element.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>manganese group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33743
code: NPO_1116
preferred name: manganese group molecular entity

iron group molecular entity
type: Class
equivalent class: Class
  intersection of: d-block molecular entity
  intersection of: Restriction
    on property: has part
    some values from: Group 8 Element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a iron group (Group-8) element.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>iron group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33744
code: NPO_1117
preferred name: iron group molecular entity

copper group molecular entity
type: Class
equivalent class: Class
  intersection of: d-block molecular entity
  intersection of: Restriction
    on property: has part
    some values from: Group 11 Element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a copper group (Group-11) element.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>copper group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33745
code: NPO_1118
preferred name: copper group molecular entity

vanadium group molecular entity
type: Class
equivalent class: Class
  intersection of: d-block molecular entity
  intersection of: Restriction
    on property: has part
    some values from: Group 5 Element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a vanadium group (Group-5) element.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>vanadium group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33746
code: NPO_1119
preferred name: vanadium group molecular entity

nickel group molecular entity
type: Class
equivalent class: Class
  intersection of: d-block molecular entity
  intersection of: Restriction
    on property: has part
    some values from: Group 10 Element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a nickel group (Group-10) element.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nickel group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33747
code: NPO_1120
preferred name: nickel group molecular entity

nickel molecular entity
type: Class
equivalent class: Class
  intersection of: nickel group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: nickel
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of nickel.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nickel molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33748
code: NPO_1138
preferred name: nickel molecular entity

platinum molecular entity
type: Class
equivalent class: Class
  intersection of: nickel group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: platinum
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of platinum.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>platinum molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33749
code: NPO_1140
preferred name: platinum molecular entity

cobalt group molecular entity
type: Class
equivalent class: Class
  intersection of: d-block molecular entity
  intersection of: Restriction
    on property: has part
    some values from: Group 9 Element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a cobalt group (Group-9) element.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cobalt group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33767
code: NPO_1121
preferred name: cobalt group molecular entity

titanium group molecular entity
type: Class
equivalent class: Class
  intersection of: d-block molecular entity
  intersection of: Restriction
    on property: has part
    some values from: Group 4 Element
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a titanium group (Group-4) element.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>titanium group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33768
code: NPO_1122
preferred name: titanium group molecular entity

organic hydroxy compound
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: hydroxyl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound which is characterized by the presence of one or more hydroxyl groups attached to carbon atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>organic hydroxy compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33822
code: NPO_201
synonym: hydroxy compound
preferred name: organic hydroxy compound

polymer
type: Class
subclass of: organic compound or molecule
subclass of: Restriction
  on property: has part
  some values from: repeat unit
subclass of: Restriction
  on property: has component part
  some values from: monomer
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polymer is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>polymer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33839
DB xref ID: MESH:D011108
code: NPO_364
comment: [definition source]: CHEBI
synonym: macromolecule
preferred name: polymer
synonym: polymer molecule

platinum coordination compound
type: Class
subclass of: coordination compound
subclass of: Restriction
  on property: has part
  some values from: platinum
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A coordination compound which contains platinum as the central atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>platinum coordination compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33862
code: NPO_297
preferred name: platinum coordination compound

rhodium molecular entity
type: Class
equivalent class: Class
  intersection of: cobalt group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: rhodium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of rhodium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>rhodium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33887
code: NPO_1129
preferred name: rhodium molecular entity

cobalt molecular entity
type: Class
equivalent class: Class
  intersection of: cobalt group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: cobalt
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of cobalt.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cobalt molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33888
code: NPO_1130
preferred name: cobalt molecular entity

silver molecular entity
type: Class
equivalent class: Class
  intersection of: copper group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: silver
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of silver.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>silver molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33964
code: NPO_1133
preferred name: silver molecular entity

gold molecular entity
type: Class
equivalent class: Class
  intersection of: copper group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: gold
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of gold.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gold molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:33969
code: NPO_1132
preferred name: gold molecular entity

organonitrogen compound
type: Class
equivalent class: Class
  intersection of: heteroorganic compound
  intersection of: Restriction
    on property: has part
    some values from: Class
      intersection of: carbon atom
      intersection of: Restriction
        on property: has bond with
        some values from: nitrogen atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organonitrogen compound is a heteroorganic compound containing at least one carbon-nitrogen bond.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>organonitrogen compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:35352
code: NPO_503
preferred name: organonitrogen compound

sulfonamide
type: Class
equivalent class: Class
  intersection of: amide
  intersection of: Restriction
    on property: has part
    some values from: sulfonamide group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A sulfonamide is an amide derived from sulfonic acids, and thus characterized by the presence of a sulfonamide group. It has the structure R-S(=O)-NH2, R-S(=O)-NH-R' or R-S(=O)-N(-R")-R', where R,R',R" denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>sulfonamide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:35358
code: NPO_908
preferred name: sulfonamide

carboxamidine
type: Class
equivalent class: Class
  intersection of: amidine
  intersection of: Restriction
    on property: has part
    some values from: carboxamidine group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amidine is an organic compound which is a derivative of a carboxylic acid, in which the hydroxy group is replaced by an amino group and the oxo group is replaced by =NR, and therefore, it has the structure R'-C(=N-R)-NH2, where R' denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carboxamidine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:35359
code: NPO_232
preferred name: carboxamidine

hydrazide
type: Class
subclass of: organic functional class
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrazide is an organic compound or molecule which is derived from an oxoacid RkE(=O)l(OH)m (l ? 0) by replacing ?OH by ?N(-R)-N(-R')-R" (R,R',R" groups commonly denote H).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydrazide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:35362
code: NPO_583
preferred name: hydrazide

carbohydrazide
type: Class
equivalent class: Class
  intersection of: hydrazide
  intersection of: Restriction
    on property: has part
    some values from: carbohydrazide group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carbohydrazide is a hyrazide derived from a carboxylic acid, and therefore has the structure R""-(C=O)-N(-R)-N(-R')-R", where R"" denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carbohydrazide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:35363
code: NPO_629
preferred name: carbohydrazide

organic disulfide
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: disulfanedyl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic disulfide is an organic compound which is characterized by the presence of a disulfanedyl group / disulfide bond. It has the structure R-S-S-R', where R,R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>organic disulfide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:35489
code: NPO_573
preferred name: organic disulfide

antineoplastic agent
type: Class
equivalent class: Class
  intersection of: anticancer drug
  intersection of: Restriction
    on property: has function
    some values from: Class
      intersection of: therapeutic function
      intersection of: Restriction
        on property: is realized in
        some values from: antineoplastic activity
subclass of: Restriction
  on property: has role
  some values from: inhibitor role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Anticancer drug, which brings about a cancer therapeutic effect by inhibiting or preventing the proliferation of neoplasms; i.e., it inhibits the maturation ,growth or spread of tumor cells.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>antineoplastic agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:35610
DB xref ID: NCIT: C274
code: NPO_777
preferred name: antineoplastic agent
synonym: antineoplastic drug

ruthenium molecular entity
type: Class
equivalent class: Class
  intersection of: iron group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: ruthenium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of ruthenium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ruthenium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:35734
code: NPO_1135
preferred name: ruthenium molecular entity

protein
type: Class
subclass of: biopolymer
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A biopolymer which is genetically encoded, the structure of which essentially consists of long chains of amino acid residues (derived from alpha aminoacids) connected by peptide bonds and have distinct and varied three-dimensional structures, usually containing alpha helices and beta sheets as well as looping and folded chains.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>protein</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:36080
code: NPO_982
preferred name: protein

quinone
type: Class
subclass of: cyclic ketone
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Cyclic ketone having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of ?CH= groups into ?C(=O)? groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>quinone</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:36141
code: NPO_774
preferred name: quinone

polyatomic entity
type: Class
equivalent class: Class
  intersection of: molecular entity
  intersection of: Restriction
    on property: has quality
    some values from: polyatomic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which consists of more than one atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>polyatomic entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:36357
code: NPO_1023
preferred name: polyatomic entity

polyatomic ion
type: Class
equivalent class: Class
  intersection of: ion
  intersection of: Restriction
    on property: has quality
    some values from: polyatomic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ion which consists of more than one atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>polyatomic ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:36358
code: NPO_1033
preferred name: polyatomic ion

carbonyl compound
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: carbonyl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carbonyl compound is an organic compound which is characterized by the presence of a carbonyl group, and therefore, has the structure R-(C=O)-R', where R, R" are organic groups or hydrogen atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carbonyl compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:36586
code: NPO_527
preferred name: carbonyl compound

acid anhydride
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: acid anhydride group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acid anhydride is an organic compound which is characterized by the presence of an acid anhydride group. It has the structure R-C(=O)-O-C(=O)-R', where R, R' stand for organic groups or hydrogen atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>acid anhydride</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:36606
code: NPO_883
preferred name: acid anhydride

organochlorine compound
type: Class
equivalent class: Class
  intersection of: heteroorganic compound
  intersection of: Restriction
    on property: has part
    some values from: Class
      intersection of: carbon atom
      intersection of: Restriction
        on property: has single bond with
        some values from: chlorine atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organochlorine compound is a compound containing at least one carbon-chlorine bond.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>organochlorine compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:36683
code: NPO_194
preferred name: organochlorine compound

inorganic ion
type: Class
equivalent class: Class
  intersection of: ion
  intersection of: Restriction
    on property: has quality
    some values from: inorganic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ion which is inorganic.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>inorganic ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:36914
code: NPO_1032
preferred name: inorganic ion

inorganic cation
type: Class
equivalent class: Class
  intersection of: cation
  intersection of: Restriction
    on property: has quality
    some values from: inorganic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cation which is inorganic.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>inorganic cation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:36915
code: NPO_1042
preferred name: inorganic cation

cation
type: Class
subclass of: ion
subclass of: Restriction
  on property: has quality
  some values from: positive charge
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ion which is positively charged.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:36916
code: NPO_1029
preferred name: cation

polonium molecular entity
type: Class
equivalent class: Class
  intersection of: chalogen molecular entity
  intersection of: Restriction
    on property: has part
    some values from: polonium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of polonium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>polonium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:36917
code: NPO_1103
preferred name: polonium molecular entity

antimony molecular entity
type: Class
equivalent class: Class
  intersection of: pnictogen molecular entity
  intersection of: Restriction
    on property: has part
    some values from: antimony
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of antimony.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>antimony molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:36919
code: NPO_1096
preferred name: antimony molecular entity

thallium molecular entity
type: Class
equivalent class: Class
  intersection of: boron group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: thallium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of thallum.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thallium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:37110
code: NPO_1106
preferred name: thallium molecular entity

gallium molecular entity
type: Class
equivalent class: Class
  intersection of: boron group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: gallium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of gallium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gallium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:37111
code: NPO_1107
preferred name: gallium molecular entity

indium molecular entity
type: Class
equivalent class: Class
  intersection of: boron group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: indium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of indium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>indium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:37112
code: NPO_1108
preferred name: indium molecular entity

astatine molecular entity
type: Class
equivalent class: Class
  intersection of: halogen molecular entity
  intersection of: Restriction
    on property: has part
    some values from: astatine
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of astatine.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>astatine molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:37138
code: NPO_1093
preferred name: astatine molecular entity

organofluorine compound
type: Class
equivalent class: Class
  intersection of: heteroorganic compound
  intersection of: Restriction
    on property: has part
    some values from: Class
      intersection of: carbon atom
      intersection of: Restriction
        on property: has bond with
        some values from: fluorine atom
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organofluorine compound is a compound containing at least one carbon-fluorine bond.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>organofluorine compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:37143
code: NPO_698
preferred name: organofluorine compound

glucan
type: Class
subclass of: homopolysaccharide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A homopolysaccharide which is composed of glucose residues.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>glucan</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:37163
DB xref ID: MESH:D005936
code: NPO_676
preferred name: glucan

homopolysaccharide
type: Class
subclass of: polysaccharide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polysaccharide, which is composed of a single type of monosaccharide residue. They are named by replacing the ending '-ose' of the sugar by '-an'.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>homopolysaccharide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:37164
code: NPO_896
comment: [definition source]: CHEBI
synonym: homoglycan
preferred name: homopolysaccharide

bismuth molecular entity
type: Class
equivalent class: Class
  intersection of: pnictogen molecular entity
  intersection of: Restriction
    on property: has part
    some values from: bismuth
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of bismuth.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>bismuth molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:37196
code: NPO_1098
preferred name: bismuth molecular entity

titanium molecular entity
type: Class
equivalent class: Class
  intersection of: titanium group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: titanium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of titanium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>titanium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:37217
code: NPO_1142
preferred name: titanium molecular entity

zirconium molecular entity
type: Class
equivalent class: Class
  intersection of: titanium group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: zirconium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of zirconium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>zirconium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:37218
code: NPO_1143
preferred name: zirconium molecular entity

palladium molecular entity
type: Class
equivalent class: Class
  intersection of: nickel group molecular entity
  intersection of: Restriction
    on property: has part
    some values from: palladium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of palladium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>palladium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:37230
code: NPO_1141
preferred name: palladium molecular entity

gadolinium (2+) ion
type: Class
subclass of: monoatomic dication
subclass of: Restriction
  on property: has part
  some values from: gadolinium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic dication of gadolinium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gadolinium (2+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:37286
code: NPO_1060
preferred name: gadolinium (2+) ion

gadolinium (4+) ion
type: Class
subclass of: monoatomic tetracation
subclass of: Restriction
  on property: has part
  some values from: gadolinium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic tetracation of gadolinium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gadolinium (4+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:37294
code: NPO_1071
preferred name: gadolinium (4+) ion

diagnostic imaging agent
type: Class
equivalent class: Class
  intersection of: Restriction
    on property: has application
    some values from: diagnostic imaging
  intersection of: Restriction
    on property: has function
    some values from: imaging function
subclass of: compound for imaging
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which is used to enhance image formation of biological structures and functions for the detection and diagnosis of disease.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>diagnostic imaging agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:37334
DB xref ID: NCIT:C1966
code: NPO_681
preferred name: diagnostic imaging agent
synonym: image enhancement agent

MRI contrast agent
type: Class
subclass of: contrast agent
subclass of: Restriction
  on property: has application
  some values from: magnetic resonance imaging
subclass of: Restriction
  on property: has property
  some values from: magnetic
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A contrast agent, which has magnetic properties and provides contrast in images captured using MRI.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>MRI contrast agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:37335
preferred name: MRI contrast agent
code: NPO_581
synonym: contrast agent in magnetic resonance imaging

radioactive imaging agent
type: Class
subclass of: contrast agent
subclass of: Restriction
  on property: has property
  some values from: radioactive
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A contrast agent, which provides contrast in images captured using radioactive imaging techniques.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>radioactive imaging agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:37336
code: NPO_361
preferred name: radioactive imaging agent

ultrasound contrast agent
type: Class
subclass of: acoustic imaging contrast agent
subclass of: Restriction
  on property: has application
  some values from: ultrasound imaging
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A contrast agent, which provides contrast in images captured using ultrasound imaging techniques.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ultrasound contrast agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:37337
code: NPO_250
synonym: contrast agent in ultrasound imaging
preferred name: ultrasound contrast agent
synonym: ultrasound imaging contrast agent

heteroatomic molecular entity
type: Class
equivalent class: Class
  intersection of: polyatomic entity
  intersection of: Restriction
    on property: has quality
    some values from: heteroatomic
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A polyatomic entity which consists of two or more chemical elements.</ncicp:def-definition><ncicp:Definition_Review_Date>111020</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>heteroatomic molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:37577
code: NPO_1024
preferred name: heteroatomic molecular entity

nitrogen mustard
type: Class
subclass of: organonitrogen compound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of organonitrogen compound, which has two ?-haloalkyl groups bound to a nitrogen atom, as in (X?C2H2?C2H2)2NR.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nitrogen mustard</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:37598
code: NPO_172
preferred name: nitrogen mustard

carboxamide
type: Class
equivalent class: Class
  intersection of: amide
  intersection of: Restriction
    on property: has part
    some values from: carboxamide group
subclass of: Restriction
  on property: has part
  some values from: acyl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carboxamide is an amide derived from carboxylic acids. It is characterized by the presence of a carboxamide group. It has the structure R-C(=O)-NH2, R-C(=O)-NH-R' or R-C(=O)-N(-R")-R', where R,R',R" stands for organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carboxamide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:37622
code: NPO_269
preferred name: carboxamide

protein kinase inhibitor
type: Class
equivalent class: Class
  intersection of: enzyme inhibitor drug
  intersection of: Restriction
    on property: has role
    some values from: Class
      intersection of: inhibitor role
      intersection of: Restriction
        on property: is realized in
        some values from: inhibition of protein kinase activity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An enzyme inhibitor, which inhibits the activity of protein kinase.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>protein kinase inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:37699
DB xref ID: NCIT: C1404
code: NPO_436
comment: inhibits phosphorylation in the signaling pathway, which regulates a variety of fundamental processes, such as cell growth, mitogenesis, metabolism, gene transcription, cell cycle control, and the immune response.
preferred name: protein kinase inhibitor

fluorescein isothiocyanate
type: Class
subclass of: organic compound or molecule
subclass of: Restriction
  on property: has property
  some values from: fluorescent
subclass of: Restriction
  on property: has part
  some values from: isothiocyanate group
subclass of: Restriction
  on property: has part
  some values from: hydroxyl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound which is derived from fluorescein by replacing a hydrogen atom of the benzene ring (the one that does not contain the hydroxyl groups), with an amine-reactive isothiocyanate group.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fluorescein isothiocyanate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:37926
synonym: FITC
code: NPO_134
preferred name: fluorescein isothiocyanate

quinazoline compound
type: Class
subclass of: organic heterobicyclic compound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quinazoline compound is a derivative of quinazoline.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>quinazoline compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:38530
code: NPO_386
preferred name: quinazoline compound

hydrazone
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: hydrazone group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrazone is an organic compound which is formally derived from aldehydes or ketones by replacing =O by =N-NH2 or =N-NH-R', and thus, characterized by a "hydrazone group." It has the structure R-C(=N-NH2)-R" or R-C(=N-NH-R')-R".</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydrazone</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:38532
code: NPO_971
preferred name: hydrazone

conjugated protein
type: Class
subclass of: protein
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A protein that contains a non-protein prosthetic group such as sugar, nucleic acid, lipid, or metal ion.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>conjugated protein</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:38560
code: NPO_578
comment: [definition source]: L. G. Wade Jr. Organic Chemistry 3rd Edition
preferred name: conjugated protein

diazo compound
type: Class
equivalent class: Class
  intersection of: organic functional class
  intersection of: Restriction
    on property: has part
    some values from: diazo group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A diazo compound is an organic compound which is characterized by the presence of a diazo group. It has the structure R=[N+]=[N-], where R denotes an organic group..</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>diazo compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:39444
code: NPO_569
preferred name: diazo compound

cyclic ketone
type: Class
subclass of: ketone
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A ketone which is a cyclic compound containing one or more ketone groups.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cyclic ketone</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:3992
code: NPO_373
preferred name: cyclic ketone

cyclophosphamide
type: Class
subclass of: nitrogen mustard
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: alkylating function
    intersection of: Restriction
      on property: is realized in
      some values from: DNA alkylation
subclass of: Restriction
  on property: has part
  some values from: phosphoramide group
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: binding function
    intersection of: Restriction
      on property: is realized in
      some values from: DNA binding
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: therapeutic function
    intersection of: Restriction
      on property: is realized in
      some values from: antineoplastic activity
subclass of: Restriction
  on property: has role
  some values from: anticancer drug role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of nitrogen mustard.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cyclophosphamide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:4027
code: NPO_890
comment: anticancer drug that induces breakage of DNA helix
preferred name: cyclophosphamide

tamoxifen
type: Class
subclass of: organic compound or molecule
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: binding function
    intersection of: Restriction
      on property: is realized in
      some values from: estrogen receptor binding
subclass of: Restriction
  on property: has role
  some values from: anticancer drug role
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: therapeutic function
    intersection of: Restriction
      on property: is realized in
      some values from: antineoplastic activity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Tamoxifen is an organic compound, which has a parent hydride, stilbin; and which blocks the effects of the hormone estrogen in the body. It is used to prevent or delay the return of breast cancer or to control its spread.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tamoxifen</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:41774
code: NPO_254
comment: modifies expression of specific genes
preferred name: tamoxifen

idarubicin
type: Class
subclass of: anthracycline
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: antibiotic role
    intersection of: Restriction
      on property: is realized in
      some values from: inhibition of cancer cell growth
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: regulator role
    intersection of: Restriction
      on property: is realized in
      some values from: regulation of DNA-dependent transcription
subclass of: Restriction
  on property: has role
  some values from: anticancer drug role
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: binding function
    intersection of: Restriction
      on property: is realized in
      some values from: DNA binding
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: inhibitor role
    intersection of: Restriction
      on property: is realized in
      some values from: inhibition of DNA topoisomerase type II activity
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: DNA intercalator role
    intersection of: Restriction
      on property: is realized in
      some values from: DNA intercalation
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: therapeutic function
    intersection of: Restriction
      on property: is realized in
      some values from: antineoplastic activity
synonym: 4-Demethoxydaunorubicin
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anthracycline which is (1S,3S)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-?-L-lyxo-hexopyranoside.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>idarubicin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:42068
code: NPO_817
comment: anticancer drug that inhibits protein activity related to DNA synthesis
preferred name: idarubicin

aldehyde group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: aldehyde
subclass of: Restriction
  on property: has part
  some values from: carbonyl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=O)H. The group is characteristic of an aldehyde wherein it is attached to the remaining part of the molecule via covalent bond with hydrogen or carbon atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>aldehyde group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:42485
code: NPO_590
preferred name: aldehyde group
synonym: formyl group

hydroxyl group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: organic hydroxy compound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group, in which an oxygen atom is bonded to a hydrogen atom, and has the structure -OH. The group is characteristic of an organic hydroxy molecule wherein it is attached to a carbon atom via a single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydroxyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:43176
code: NPO_941
synonym: hydroxy group
preferred name: hydroxyl group
comment: prefix: hydroxy suffix: -ol

methotrexate
type: Class
subclass of: pteridine compound
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: antagonist role
    intersection of: Restriction
      on property: is realized in
      some values from: inhibition of folic acid metabolism
subclass of: Restriction
  on property: has part
  some values from: pteridine
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: therapeutic function
    intersection of: Restriction
      on property: is realized in
      some values from: antineoplastic activity
subclass of: Restriction
  on property: has part
  some values from: primary amine group
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: inhibitor role
    intersection of: Restriction
      on property: is realized in
      some values from: inhibition of dihydrofolate reductase activity
subclass of: Restriction
  on property: has part
  some values from: carboxamide group
subclass of: Restriction
  on property: has part
  some values from: carboxyl group
subclass of: Restriction
  on property: has role
  some values from: anticancer drug role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A pteridine compound has a pteridine substructure; which has functional parent, L-glutamic acid; which has other substructures that classify it a monocarboxylic acid amide and a dicarboxylic acid.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>methotrexate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: An antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities. Methotrexate binds to and inhibits the enzyme dihydrofolate reductase, resulting in inhibition of purine nucleotide and thymidylate synthesis and, subsequently, inhibition of DNA and RNA syntheses. Methotrexate also exhibits potent immunosuppressant activity although the mechanism(s) of actions is unclear.
DB xref ID: CHEBI:44185
DB xref ID: NCIT:C642
code: NPO_741
preferred name: methotrexate

paclitaxel
type: Class
subclass of: diterpenoid
subclass of: Restriction
  on property: has role
  some values from: anticancer drug role
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: therapeutic function
    intersection of: Restriction
      on property: is realized in
      some values from: antineoplastic activity
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: inhibitor role
    intersection of: Restriction
      on property: is realized in
      some values from: negative regulation of mitosis
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: binding function
    intersection of: Restriction
      on property: is realized in
      some values from: beta-tubulin binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A diterpenoid, which consists of a tetracyclic core called baccatin III, and an amide tail.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>paclitaxel</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:45863
DB xref ID: MESH: D017239
DB xref ID: NCIT:C1411
code: NPO_860
comment: Paclitaxel is isolated from the bark of the Pacific yew tree.
preferred name: paclitaxel

5-fluorouracil
type: Class
subclass of: organofluorine compound
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: therapeutic function
    intersection of: Restriction
      on property: is realized in
      some values from: antineoplastic activity
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: antimetabolite role
    intersection of: Restriction
      on property: is realized in
      some values from: negative regulation of DNA replication
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: inhibitor role
    intersection of: Restriction
      on property: is realized in
      some values from: inhibition of thymidylate synthase activity
subclass of: Restriction
  on property: has role
  some values from: anticancer drug role
preferred name: 5-fluorouracil
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organofluorine compound, which has uracil as the funcitonal parent.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>5-fluorouracil</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:46345
code: NPO_365
comment: anticancer drug that inhibits protein activity related to DNA synthesis

mineral
type: Class
subclass of: chemical substance
subclass of: Restriction
  on property: has quality
  some values from: solid state
subclass of: Restriction
  on property: has quality
  some values from: inorganic
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A mineral is a naturally occurring chemical substance formed through geological processes that has a characteristic chemical composition, a highly ordered atomic structure and specific physical properties.</ncicp:def-definition><ncicp:Definition_Review_Date>111020</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>mineral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:46662
code: NPO_1563
preferred name: mineral

phosphate mineral
type: Class
subclass of: mineral
subclass of: Restriction
  on property: has part
  some values from: phosphorus
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mineral which contains phosphate anions.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>phosphate mineral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:46723
code: NPO_1564
preferred name: phosphate mineral

solvent
type: Class
subclass of: liquid
subclass of: Restriction
  on property: has role
  some values from: solvent role
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A liquid which can dissolve other substancees (solutes) without any change in their chemical composition.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>CHEBI</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>solvent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:46787
code: NPO_1831
preferred name: solvent

poly(ethylene glycol)
type: Class
subclass of: polymer
subclass of: Restriction
  on property: has part
  some values from: hydroxyl group
subclass of: Restriction
  on property: has part
  some values from: ether group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polymer made by the polymerization of ethylene oxide.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>poly(ethylene glycol)</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:46793
code: NPO_444
synonym: PEG
preferred name: poly(ethylene glycol)

carboxyl group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: part of
  some values from: carboxylic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=O)-OH. The group is characteristic of carboxylic acid compounds, wherein it is attached to a hydrogen atom or a carbon atom by a single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>carboxyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:46883
code: NPO_838
preferred name: carboxyl group

halo group
type: Class
subclass of: functional group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -X, where 'X' denotes a halogen atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>halo group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:47854
code: NPO_135
preferred name: halo group

acryloyl group
type: Class
subclass of: functional group
subclass of: Restriction
  on property: has part
  some values from: carbonyl group
subclass of: Restriction
  on property: part of
  some values from: acryloyl compound
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=O)-CH=CH2, and the group is characteristic of acryloyl compounds.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>acryloyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:48077
code: NPO_215
preferred name: acryloyl group

anthracycline
type: Class
subclass of: polyketide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polyketide which has a tetrahydronaphthacenedione ring structure attached by a glycosidic linkage to the amino sugar daunosamine.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>anthracycline</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:48120
code: NPO_539
preferred name: anthracycline

angiogenesis inhibitor
type: Class
equivalent class: Class
  intersection of: antineoplastic agent
  intersection of: Restriction
    on property: has function
    some values from: Class
      intersection of: therapeutic function
      intersection of: Restriction
        on property: is realized in
        some values from: tumor angiogenesis inhibition
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: inhibitor role
    intersection of: Restriction
      on property: is realized in
      some values from: tumor angiogenesis inhibition
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antineoplastic agent that slows down or prevents the formation and growth of blood or lymphatic vessels. In cancer therapy, angiogenesis inhibitors target blood vessels that supply tumors, thereby inhibiting tumor growth.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>angiogenesis inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:48422
DB xref ID: MESH: D020533
DB xref ID: NCIT: C1742
code: NPO_595
synonym: angiogenesis antagonist
preferred name: angiogenesis inhibitor

cyano group
type: Class
subclass of: functional group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cyano group is a substituent group from hydrogen cyanide, and has the structure -C#N.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cyano group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:48819
code: NPO_588
preferred name: cyano group

cobalt (2+) ion
type: Class
subclass of: monoatomic dication
subclass of: Restriction
  on property: has part
  some values from: cobalt
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic dication of cobalt.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cobalt (2+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:48828
code: NPO_1059
preferred name: cobalt (2+) ion

etoposide
type: Class
subclass of: organic compound or molecule
subclass of: Restriction
  on property: has role
  some values from: Class
    intersection of: inhibitor role
    intersection of: Restriction
      on property: is realized in
      some values from: inhibition of DNA topoisomerase type II activity
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: therapeutic function
    intersection of: Restriction
      on property: is realized in
      some values from: antineoplastic activity
subclass of: Restriction
  on property: has role
  some values from: anticancer drug role
synonym: (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-?-D-glucopyranoside
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound or molecule, which has a functional parent, podophyllotoxin; which has substructure that classifies it as a beta-D-glucoside.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>etoposide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:4911
code: NPO_168
preferred name: etoposide

molybdenum (6+) ion
type: Class
subclass of: monoatomic hexacation
subclass of: Restriction
  on property: has part
  some values from: molybdenum
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic hexacation of molybdenum.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>molybdenum (6+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:49446
code: NPO_1074
preferred name: molybdenum (6+) ion

silver (1+) ion
type: Class
subclass of: monoatomic monocation
subclass of: Restriction
  on property: has part
  some values from: silver
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monatomic monocation of silver.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>silver (1+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:49468
code: NPO_1062
preferred name: silver (1+) ion

gold (1+) ion
type: Class
subclass of: monoatomic monocation
subclass of: Restriction
  on property: has part
  some values from: gold
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic monocation of gold.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gold (1+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:49482
code: NPO_1061
preferred name: gold (1+) ion

europium (2+) ion
type: Class
subclass of: monoatomic dication
subclass of: Restriction
  on property: has part
  some values from: europium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic dication of europium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>europium (2+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:49588
code: NPO_1058
preferred name: europium (2+) ion

gadolinium (3+) ion
type: Class
subclass of: monoatomic trication
subclass of: Restriction
  on property: has part
  some values from: gadolinium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic trication of gadolinium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gadolinium (3+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:49618
code: NPO_1068
preferred name: gadolinium (3+) ion

gefitinib
type: Class
subclass of: quinazoline compound
subclass of: Restriction
  on property: has function
  some values from: Class
    intersection of: binding function
    intersection of: Restriction
      on property: is realized in
      some values from: epidermal growth factor receptor binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of quinazoline compound.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gefitinib</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:49668
synonym: Iressa
code: NPO_123
synonym: ZD-1839
comment: drug directed against intracellular domain of membrane receptor
preferred name: gefitinib
comment: removed 'has_role some epidermal growth factor receptor tyrosine kinase inhibitor'

tungsten (6+) ion
type: Class
subclass of: monoatomic hexacation
subclass of: Restriction
  on property: has part
  some values from: tungsten
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic hexacation of tungsten.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tungsten (6+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:49955
code: NPO_1075
preferred name: tungsten (6+) ion

monoatomic tetraanion
type: Class
subclass of: monoatomic anion
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic anion which has ionic charge -4.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>monoatomic tetraanion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:50086
code: NPO_1044
preferred name: monoatomic tetraanion

iron (III) oxide
type: Class
subclass of: iron oxide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iron oxide with the chemical formula Fe2O3.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>iron (III) oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:50819
code: NPO_1149
synonym: ferric oxide
preferred name: iron (III) oxide

iron (II) oxide
type: Class
subclass of: iron oxide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iron oxide with the chemical formula FeO.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>iron (II) oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:50820
code: NPO_1150
synonym: ferrous oxide
preferred name: iron (II) oxide

iron (II,III) oxide
type: Class
subclass of: iron oxide
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iron oxide with the chemical formula Fe3O4.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>iron (II,III) oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:50821
code: NPO_1151
synonym: ferrosoferric oxide
preferred name: iron (II,III) oxide

nitrogen molecular entity
type: Class
equivalent class: Class
  intersection of: pnictogen molecular entity
  intersection of: Restriction
    on property: has part
    some values from: nitrogen
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of nitrogen.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nitrogen molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:51143
code: NPO_1097
preferred name: nitrogen molecular entity

apatite
type: Class
subclass of: phosphate mineral
subclass of: Restriction
  on property: has part
  some values from: oxygen
subclass of: Restriction
  on property: has part
  some values from: calcium
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phosphate mineral with the general formula Ca5(PO4)3X where X = OH, F or Cl.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>apatite</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:52254
code: NPO_1565
preferred name: apatite

hydroxyapatite
type: Class
subclass of: apatite
subclass of: Restriction
  on property: has part
  some values from: hydroxyl group
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phosphate mineral with the formula Ca5(PO4)3(OH).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydroxyapatite</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: CHEBI:52255
code: NPO_1566
preferred name: hydroxyapatite
synonym: hydroxylapatite

infrared spectroscopy
type: Class
subclass of: absorption spectroscopy
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An absorption spectroscopic technique in which a beam of infrared light is used to irradiate a sample. The IR absorption spectra obtained with this technique, is used to identify compounds or investigate sample composition based on the correlation of absorption bands in the spectrum of the unknown compound with known absorption frequencies for specific types of bonds.</ncicp:def-definition><ncicp:Definition_Review_Date>100611</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>infrared spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: FIX:0000015
synonym: IR spectroscopy
code: NPO_1473
comment: The technique is based on the fact that molecules have specific frequencies at which they rotate or vibrate corresponding to discrete energy levels (vibrational modes).
preferred name: infrared spectroscopy

ultraviolet/visible spectroscopy
type: Class
subclass of: absorption spectroscopy
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An absorption spectroscopic technique in which the irradiating light has wavelengths within the ultraviolet and visible regions of the electromagnetic spectrum.</ncicp:def-definition><ncicp:Definition_Review_Date>100614</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>ultraviolet/visible spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: FIX:0000016
code: NPO_1475
synonym: UV-Vis spectroscopy
preferred name: ultraviolet/visible spectroscopy

x-ray photoelectron spectroscopy
type: Class
subclass of: absorption spectroscopy
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which is carried out in vaccum, and is used to estimate the elemental composition and chemical state of the elements on the surface of a material by irradiating the material surface with a beam of soft monochromatic (magnesium/aluminum) X-rays and measuring the kinetic energy of photoelectrons emitted from the core orbitals of the surface elements within a few nm from the material surface.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>x-ray photoelectron spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: ESCA
synonym: Electron Spectroscopy for Chemical Analysis
DB xref ID: FIX:0000041
DB xref ID: NCIT:C78871
code: NPO_1471
comment: Photoelectrons are collected and analyzed by the XPS instrument to produce a spectrum of emission intensity versus electron binding energy. Since each element has a unique set of binding energies, XPS can be used to identify the elements on the surface. Also, peak areas at nominal binding energies can be used to quantify concentration of the elements. Small shifts in these binding energies (chemical shifts) provide powerful information about sample chemical states and short-range chemistry .
synonym: XPS
comment: [definition: based on NCIT, http://encyclopedia.thefreedictionary.com, http://www.chem.umd.edu/facility/xps.php]
preferred name: x-ray photoelectron spectroscopy

chromatography
type: Class
subclass of: separation technique
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A separation technique for separation of mixtures, in which a mixture dissolved in a mobile liquid or gas medium, is passed through a stationary adsorbing medium to separate the components based on differential affinities of the components for the mobile medium and for the stationary medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100616</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>chromatography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: FIX:0000053
code: NPO_1458
comment: [definition adapted from NCIT, WordNet, http://encyclopedia.thefreedictionary.com/chromatography]
preferred name: chromatography

Raman spectroscopy
type: Class
subclass of: light scattering spectroscopy
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which is based on the detection of inelastically scattered monochromatic light from a laser in the visible, near infrared, or near ultraviolet range, by a substance (or sample under investigation). A laser beam of a given wavelength is used to irradiate a spot on the sample under investigation. The inelastically scattered light ( photons scattered at lower frequencies or higher wavelengths compared to that of the incident photons (Raman effect)), contains information about the energies of molecular vibrations and rotations, and these depend on the particular atoms or ions that comprise the molecule, the chemical bonds connect them, the symmetry of their molecule structure, and the physico-chemical environment where they reside.</ncicp:def-definition><ncicp:Definition_Review_Date>100527</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Raman spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: FIX:0000058
DB xref ID: NCIT:C17157
code: NPO_1472
preferred name: Raman spectroscopy
comment: [definition: adapted from http://epsc.wustl.edu/haskin-group/Raman/faqs.htm, http://encyclopedia.thefreedictionary.com]

gas chromatography
type: Class
subclass of: chromatography by mobile phase state
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chromatography technique in which the mobile phase is a gas.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gas chromatography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: FIX:0000098
code: NPO_1460
preferred name: gas chromatography

contact atomic force microscopy
type: Class
subclass of: atomic force microscopy
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atomic force microscopy technique in which the tip of the cantilever is in contact with the sample's surface. In the contact mode, the overall force between the tip and the surface is repulsive and it is kept constant during scanning by maintaining a constant deflection, and therefore constant height above the surface.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>contact atomic force microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: FIX:0000116
code: NPO_1448
comment: [definition: adapted from http://en.wikipedia.org, http://www.nanoscience.com/education/AFM.html]
synonym: contact AFM
preferred name: contact atomic force microscopy

non contact atomic force micrsocopy
type: Class
subclass of: atomic force microscopy
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atomic force microscopy technique in which the tip of the cantilever is not in contact with sample's surface. In non contact mode, the overall force between the tip and the surface is attractive. The cantilever is oscillated at a frequency slightly above its resonance frequency where the amplitude of oscillation is typically a few nanometers (<10 nm). The van der Waals forces, which are strongest from 1 nm to 10 nm above the surface, or any other long range force which extends above the surface acts to decrease the resonance frequency of the cantilever. This decrease in resonance frequency combined with the feedback loop system maintains a constant oscillation amplitude or frequency by adjusting the average tip-to-sample distance. Measuring the tip-to-sample distance at each (x,y) data point allows the scanning software to construct a topographic image of the sample surface.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>non contact atomic force micrsocopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: FIX:0000117
synonym: NC-AFM
code: NPO_1449
preferred name: non contact atomic force micrsocopy

magnetic force microscopy
type: Class
subclass of: non contact atomic force micrsocopy
subclass of: Restriction
  on property: uses instrument
  some values from: magnetic force microscope
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A non contact atomic force microscopy technique based on the use of magnetic force microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>magnetic force microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: FIX:0000118
code: NPO_1450
preferred name: magnetic force microscopy

near-infrared spectroscopy
type: Class
subclass of: infrared spectroscopy
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An infrared spectroscopy where the beam of light that irradiates the sample has wavelengths within the near-infrared region of the electromagnetic spectrum.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>near-infrared spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: FIX:0000321
synonym: NIR spectroscopy
code: NPO_1474
preferred name: near-infrared spectroscopy

light scattering
type: Class
equivalent class: Class
  union of: phase analysis light scattering
  union of: dynamic light scattering
subclass of: technique
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A technique based on the disperson of light or electromagnetic radiation into a range of directions by virtue of its interaction with a material medium through which it passes.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>light scattering</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: FIX:0000402
DB xref ID: NCIT:C62323
code: NPO_1466
comment: [definition: adapted from NCIT]
preferred name: light scattering
synonym: light scattering technique

chromatography by mobile phase state
type: Class
subclass of: chromatography
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chromatography technique classified based on the phase of the mobile medium.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>chromatography by mobile phase state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: FIX:0000607
code: NPO_1459
preferred name: chromatography by mobile phase state
synonym: chromatography by physical state of the mobile phase

liquid chromatography
type: Class
subclass of: chromatography by mobile phase state
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chromatography technique in which the mobile phase is a liquid.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>liquid chromatography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: FIX:0000608
synonym: LC
code: NPO_1461
preferred name: liquid chromatography

chromatography by separation mechanism
type: Class
subclass of: chromatography
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chromatography technique classified based on the mechanism of separation.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>chromatography by separation mechanism</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: FIX:0000610
code: NPO_1463
preferred name: chromatography by separation mechanism

size-exclusion chromatography
type: Class
subclass of: chromatography by separation mechanism
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chromatography technique which uses porous gels to separate solute molecules or particles based on size.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>size-exclusion chromatography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: FIX:0000626
synonym: GPC
DB xref ID: NCIT:C16433
code: NPO_1464
synonym: SEC
synonym: gel filtration chromatography
synonym: gel permeation chromatography
preferred name: size-exclusion chromatography

high pressure liquid chromatography
type: Class
subclass of: liquid chromatography
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A liquid chromatography technique in which the sample is forced by a liquid (mobile phase) at high pressure, through a column that is packed with a solid stationary phase.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>high pressure liquid chromatography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: FIX:0000630
synonym: HPLC
DB xref ID: NCIT: C16434
code: NPO_1462
synonym: high performance liquid chromatography
preferred name: high pressure liquid chromatography

capillary electrophoresis
type: Class
subclass of: electrophoresis
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electrophoresis technique, in which a sample is introduced into a capillary tube and the components are separated by the application of high voltage. Due to the large surface to volume ratio, cooling is more efficient, allowing use of higher voltages. As a result, separation occurs more quickly and sensitivity is increased. The technique allows for separation of proteins, nucleic acids, and carbohydrates.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>capillary electrophoresis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: FIX:0000836
DB xref ID: NCIT:C17637
code: NPO_1457
preferred name: capillary electrophoresis

angiogenesis
type: Class
subclass of: anatomical structure formation
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>angiogenesis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0001525
code: NPO_657
preferred name: angiogenesis
synonym: blood vessel formation from pre-existing blood vessels

molecular function
type: Class
subclass of: process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Elemental activity, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>molecular function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0003674
code: NPO_362
comment: [source]: GO
synonym: molecular activity
preferred name: molecular function

nucleic acid binding
type: Class
subclass of: binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively and non-covalently with any nucleic acid.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nucleic acid binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0003676
code: NPO_1620
preferred name: nucleic acid binding

DNA binding
type: Class
subclass of: nucleic acid binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any molecular function by which a gene product interacts selectively with DNA (deoxyribonucleic acid).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>DNA binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: DNA binding
DB xref ID: GO:0003677
code: NPO_1621
synonym: microtubule/chromatin interaction
synonym: plasmid binding

antigen binding
type: Class
subclass of: binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>antigen binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0003823
code: NPO_959
preferred name: antigen binding

enzyme activity
type: Class
subclass of: molecular function
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. [source: ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>enzyme activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0003824
code: NPO_584
synonym: catalytic activity
preferred name: enzyme activity

DNA topoisomerase activity
type: Class
subclass of: enzyme activity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>DNA topoisomerase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: DNA topoisomerase activity
DB xref ID: GO:0003916
code: NPO_700

DNA topoisomerase type II activity
type: Class
subclass of: DNA topoisomerase activity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>DNA topoisomerase type II activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: DNA topoisomerase (ATP-hydrolyzing) activity
preferred name: DNA topoisomerase type II activity
DB xref ID: GO:0003918
code: NPO_450

dihydrofolate reductase activity
type: Class
subclass of: enzyme activity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dihydrofolate reductase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0004146
code: NPO_593
preferred name: dihydrofolate reductase activity

protein kinase activity
type: Class
subclass of: enzyme activity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. [source: MetaCyc:PROTEIN-KINASE-RXN]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>protein kinase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0004672
code: NPO_953
preferred name: protein kinase activity

protein tyrosine kinase activity
type: Class
subclass of: protein kinase activity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. [source: EC:2.7.10]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>protein tyrosine kinase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0004713
code: NPO_217
preferred name: protein tyrosine kinase activity

thymidylate synthase activity
type: Class
subclass of: enzyme activity
synonym: 5,10-methylenetetrahydrofolate:dUMP C-methyltransferase activity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP. [source: EC:2.1.1.45]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thymidylate synthase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0004799
code: NPO_820
synonym: TMP synthetase activity
synonym: dTMP synthase activity
synonym: methylenetetrahydrofolate:dUMP C-methyltransferase activity
preferred name: thymidylate synthase activity
synonym: thymidylate synthetase activity

receptor activity
type: Class
subclass of: molecular function
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Combining with an extracellular or intracellular messenger to initiate a change in cell activity.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>receptor activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0004872
code: NPO_1593
preferred name: receptor activity

receptor binding
type: Class
subclass of: protein binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. [source: GOC:bf, GOC:ceb, ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>receptor binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0005102
code: NPO_780
preferred name: receptor binding

epidermal growth factor receptor binding
type: Class
subclass of: receptor binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with the epidermal growth factor receptor. [source: GOC:ai]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>epidermal growth factor receptor binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: EGF receptor binding
synonym: EGFR binding
DB xref ID: GO:0005154
code: NPO_165
synonym: TGF-alpha receptor binding
preferred name: epidermal growth factor receptor binding
synonym: transforming growth factor alpha receptor binding

binding
type: Class
subclass of: molecular function
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0005488
code: NPO_547
preferred name: binding

protein binding
type: Class
subclass of: binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). [source: GOC:go_curators]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>protein binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0005515
code: NPO_170
synonym: protein amino acid binding
preferred name: protein binding

cellular component
type: Class
equivalent class: Class
  intersection of: biological material entity
  intersection of: Class
    union of: Restriction
      on property: contained in
      some values from: intracellular space
    union of: Restriction
      on property: contained in
      some values from: extracellular space
    union of: Restriction
      on property: part of
      some values from: cell
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A material entity, which is the part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>Gene Ontology (GO)</ncicp:attr><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cellular component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0005575
code: NPO_1008
preferred name: cellular component

extracellular space
type: Class
subclass of: material site
subclass of: Restriction
  on property: contains
  some values from: extracellular fluid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. [source: GO]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>extracellular space</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: FMA:70022
DB xref ID: GO:0005615
code: NPO_1580
preferred name: extracellular space
synonym: intercellular space

cell
type: Class
subclass of: biological material entity
subclass of: Restriction
  on property: has quality
  some values from: cell concentration
subclass of: Restriction
  on property: has part
  some values from: intracellular space
definition: <ncicp:ComplexDefinition><ncicp:def-definition>A material entity which is the basic structural and functional unit of all organisms. It includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0005623
code: NPO_1009
preferred name: cell

DNA metabolic process
type: Class
equivalent class: Class
  intersection of: metabolic process
  intersection of: Restriction
    on property: has participant
    some values from: deoxyribonucleic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. [source: ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>DNA metabolic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: DNA metabolic process
synonym: DNA metabolism
DB xref ID: GO:0006259
code: NPO_1014

DNA replication
type: Class
subclass of: cellular biopolymer biosynthetic process
subclass of: Restriction
  on property: has output participant
  some values from: deoxyribonucleic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>DNA replication</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
synonym: DNA biosynthesis
preferred name: DNA replication
synonym: DNA synthesis
DB xref ID: GO:0006260
code: NPO_142

DNA modification
type: Class
subclass of: cellular biopolymer biosynthetic process
subclass of: Restriction
  on property: has participant
  some values from: deoxyribonucleic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>DNA modification</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: DNA modification
DB xref ID: GO_0006304
code: NPO_1624

DNA alkylation
type: Class
subclass of: DNA modification
subclass of: Restriction
  on property: has agent
  some values from: DNA alkylating agent
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>DNA alkylation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: DNA alkylation
DB xref ID: GO:0006305
code: NPO_1625

transcription
type: Class
subclass of: cellular biopolymer biosynthetic process
subclass of: Restriction
  on property: has output participant
  some values from: Class
    union of: deoxyribonucleic acid
    union of: ribonucleic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The synthesis of either RNA on a template of DNA or DNA on a template of RNA. [source: ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>transcription</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0006350
code: NPO_1015
preferred name: transcription

DNA-dependent transcription
type: Class
subclass of: transcription
subclass of: Restriction
  on property: has output participant
  some values from: ribonucleic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The synthesis of RNA on a template of DNA.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>DNA-dependent transcription</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
preferred name: DNA-dependent transcription
DB xref ID: GO:0006351
code: NPO_840

regulation of DNA-dependent transcription
type: Class
equivalent class: Restriction
  on property: regulates
  some values from: DNA-dependent transcription
subclass of: regulation of biological process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that modulates the frequency, rate or extent of DNA-dependent transcription.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>regulation of DNA-dependent transcription</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0006355
code: NPO_1650
preferred name: regulation of DNA-dependent transcription

endocytosis
type: Class
subclass of: cellular uptake of extracellular material
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Cellular uptake of extracellular materials within membrane-limited vacuoles or microvesicles.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>endocytosis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0006897
DB xref ID: NCIT: C16544
code: NPO_299
comment: [definition source]: NCI_Thesaurus
preferred name: endocytosis

phagocytosis
type: Class
subclass of: endocytosis
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The process whereby phagocytes engulf external particulate material. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>phagocytosis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0006909
code: NPO_1368
preferred name: phagocytosis

apoptosis
type: Class
subclass of: programmed cell death
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle the cell and result in cell death. Apoptosis begins internally with condensation and subsequent fragmentation of the cell nucleus (blebbing) while the plasma membrane remains intact. Other characteristics of apoptosis include DNA fragmentation and the exposure of phosphatidyl serine on the cell surface. [source: GOC:go_curators, ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>apoptosis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0006915
code: NPO_548
preferred name: apoptosis
synonym: apoptotic programmed cell death
synonym: programmed cell death by apoptosis

mitosis
type: Class
subclass of: cell cycle phase
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Progression through mitosis, the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother. [source: GOC:ma, ISBN:0198547684]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>mitosis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0007067
code: NPO_712
preferred name: mitosis

cell adhesion
type: Class
subclass of: cellular process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. [source: GOC:hb, GOC:pf]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cell adhesion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0007155
code: NPO_997
preferred name: cell adhesion

negative regulation of cell adhesion
type: Class
equivalent class: Restriction
  on property: negatively regulates
  some values from: cell adhesion
subclass of: negative regulation of biological process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process that stops, prevents or reduces the frequency, rate or extent of cell adhesion.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>negative regulation of cell adhesion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: An inhibition which involves interference with, or restraint of, the activities of biologic molecules, biologic complexes, or subcellular components that promote the adherence of cells to surfaces or to other cells. [NCIT definition]
DB xref ID: GO:0007162
DB xref ID: NCIT:C40708
code: NPO_1635
synonym: cell adhesion inhibition
synonym: down regulation of cell adhesion
synonym: down-regulation of cell adhesion
synonym: downregulation of cell adhesion
synonym: inhibition of cell adhesion
preferred name: negative regulation of cell adhesion

blood coagulation
type: Class
subclass of: developmental process
subclass of: Restriction
  on property: has part
  some values from: blood coagulation pathway
definition: <ncicp:ComplexDefinition><ncicp:def-definition>For definition, please refer to the Gene Ontology (v. 1.1.2341).</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>GO (v. 1.1.2341)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>blood coagulation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1988
preferred name: blood coagulation

cytoskeletal protein binding
type: Class
subclass of: protein binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton. [source: GOC:mah]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cytoskeletal protein binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0008092
code: NPO_984
preferred name: cytoskeletal protein binding

biological process
type: Class
subclass of: process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>biological process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0008150
code: NPO_427
comment: [source]: GO
preferred name: biological process
synonym: physiological process

metabolic process
type: Class
subclass of: biological process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. [source: GOC:go_curators, ISBN:0198547684]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>metabolic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0008152
code: NPO_1004
preferred name: metabolic process
synonym: metabolism

negative regulation of DNA replication
type: Class
equivalent class: Restriction
  on property: negatively regulates
  some values from: DNA replication
subclass of: negative regulation of biological process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>negative regulation of DNA replication</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0008156
code: NPO_1636
synonym: down regulation of DNA replication
synonym: down-regulation of DNA replication
synonym: downregulation of DNA replication
synonym: inhibition of DNA replication
preferred name: negative regulation of DNA replication

cell death
type: Class
subclass of: cellular process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. [source: GOC:ems]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cell death</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0008219
code: NPO_995
preferred name: cell death

biosynthetic process
type: Class
subclass of: metabolic process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. [source: GOC:curators, ISBN:0198547684]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>biosynthetic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0009058
code: NPO_1005
synonym: anabolism
synonym: biosynthesis
preferred name: biosynthetic process

cellular process
type: Class
equivalent class: Class
  intersection of: biological process
  intersection of: Restriction
    on property: has participant
    some values from: cell
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [source: GOC:go_curators, GOC:isa_complete]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cellular process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0009987
code: NPO_994
synonym: cellular physiological process
preferred name: cellular process

programmed cell death
type: Class
subclass of: cell death
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Cell death resulting from activation of endogenous cellular processes. [source: GOC:lr]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>programmed cell death</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0012501
code: NPO_996
preferred name: programmed cell death

tubulin binding
type: Class
subclass of: cytoskeletal protein binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with monomeric or multimeric forms of tubulin, including microtubules. [source: GOC:clt]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tubulin binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0015631
code: NPO_814
preferred name: tubulin binding

RNA metabolic process
type: Class
equivalent class: Class
  intersection of: metabolic process
  intersection of: Restriction
    on property: has participant
    some values from: ribonucleic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. [source: ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>RNA metabolic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0016070
code: NPO_1016
preferred name: RNA metabolic process
synonym: RNA metabolism

cell-cell adhesion
type: Class
subclass of: cell adhesion
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The attachment of one cell to another cell via adhesion molecules. [source: GOC:hb]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cell-cell adhesion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0016337
code: NPO_479
preferred name: cell-cell adhesion

negative regulation of angiogenesis
type: Class
equivalent class: Restriction
  on property: negatively regulates
  some values from: angiogenesis
subclass of: negative regulation of biological process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops, prevents or reduces the frequency, rate or extent of angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>negative regulation of angiogenesis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0016525
code: NPO_1646
synonym: angiogenesis inhibition
synonym: down regulation of angiogenesis
synonym: down-regulation of angiogenesis
synonym: downregulation of angiogenesis
synonym: inhibition of angiogenesis
preferred name: negative regulation of angiogenesis

cell cycle process
type: Class
subclass of: cellular process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. [source: GOC:isa_complete]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cell cycle process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0022402
code: NPO_998
preferred name: cell cycle process

cell cycle phase
type: Class
subclass of: cell cycle process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events. [source: GOC:isa_complete]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cell cycle phase</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0022403
code: NPO_999
preferred name: cell cycle phase

estrogen receptor binding
type: Class
subclass of: steroid hormone receptor binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with an estrogen receptor.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>estrogen receptor binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0030331
code: NPO_575
preferred name: estrogen receptor binding

developmental process
type: Class
subclass of: biological process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. [source: GOC:isa_complete]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>developmental process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0032502
code: NPO_992
preferred name: developmental process

RNA biosynthetic process
type: Class
equivalent class: Class
  intersection of: RNA metabolic process
  intersection of: Restriction
    on property: has output participant
    some values from: ribonucleic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. [source: GOC:mah]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>RNA biosynthetic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0032774
code: NPO_1017
synonym: RNA anabolism
synonym: RNA biosynthesis
preferred name: RNA biosynthetic process
synonym: RNA formation
synonym: RNA synthesis

cellular biopolymer metabolic process
type: Class
equivalent class: Class
  intersection of: metabolic process
  intersection of: Restriction
    on property: has participant
    some values from: biopolymer
  intersection of: Restriction
    on property: has participant
    some values from: cell
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells. [source: GOC:mah]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cellular biopolymer metabolic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0034960
code: NPO_1012
preferred name: cellular biopolymer metabolic process
synonym: cellular biopolymer metabolism

cellular biopolymer biosynthetic process
type: Class
equivalent class: Class
  intersection of: biopolymer biosynthetic process
  intersection of: Restriction
    on property: has participant
    some values from: cell
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells. [source: GOC:mah]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cellular biopolymer biosynthetic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0034961
code: NPO_1007
synonym: cellular biopolymer biosynthesis
preferred name: cellular biopolymer biosynthetic process

nuclear hormone receptor binding
type: Class
subclass of: hormone receptor binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with a nuclear hormone receptor, a ligand-dependent receptor found in the nucleus of the cell. [source: GOC:bf]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nuclear hormone receptor binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0035257
code: NPO_798
preferred name: nuclear hormone receptor binding

steroid hormone receptor binding
type: Class
subclass of: nuclear hormone receptor binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with a steroid hormone receptor. [source: GOC:bf]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>steroid hormone receptor binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0035258
code: NPO_958
preferred name: steroid hormone receptor binding

tumor necrosis factor biosynthetic process
type: Class
subclass of: cellular biopolymer biosynthetic process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis. [source: GOC:jl, PMID:10891884]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>tumor necrosis factor biosynthetic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0042533
code: NPO_647
synonym: TNF alpha biosynthesis
synonym: tumor necrosis factor alpha biosynthesis
synonym: tumor necrosis factor anabolism
synonym: tumor necrosis factor biosynthesis
preferred name: tumor necrosis factor biosynthetic process
synonym: tumor necrosis factor synthesis

inhibition of tumor necrosis factor biosynthetic process
type: Class
equivalent class: Restriction
  on property: negatively regulates
  some values from: tumor necrosis factor biosynthetic process
subclass of: negative regulation of biological process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>inhibition of tumor necrosis factor biosynthetic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0042536
code: NPO_1662
preferred name: inhibition of tumor necrosis factor biosynthetic process

alpha-tubulin binding
type: Class
subclass of: tubulin binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with the microtubule constituent protein alpha-tubulin. [source: GOC:jl]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>alpha-tubulin binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0043014
code: NPO_600
preferred name: alpha-tubulin binding

gamma-tubulin binding
type: Class
subclass of: tubulin binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with the microtubule constituent protein gamma-tubulin. [source: GOC:jl]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gamma-tubulin binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0043015
code: NPO_512
preferred name: gamma-tubulin binding

positive regulation of enzyme activity
type: Class
equivalent class: Restriction
  on property: positively regulates
  some values from: enzyme activity
subclass of: positive regulation of molecular function
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases the activity of an enzyme.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>positive regulation of enzyme activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0043085
code: NPO_1655
synonym: activation of enzyme activity
preferred name: positive regulation of enzyme activity
synonym: stimulation of enzyme activity
synonym: up regulation of enzyme activity
synonym: up-regulation of enzyme activity
synonym: upregulation of enzyme activity

enzyme inhibition
type: Class
equivalent class: Restriction
  on property: negatively regulates
  some values from: enzyme activity
subclass of: negative regulation of molecular function
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of an enzyme.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>enzyme inhibition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0043086
code: NPO_1632
DB xref ID: REX:0000233
synonym: down regulation of enzyme activity
preferred name: enzyme inhibition
synonym: inhibition of enzyme activity

biopolymer metabolic process
type: Class
equivalent class: Class
  intersection of: metabolic process
  intersection of: Restriction
    on property: has participant
    some values from: biopolymer
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins. [source: GOC:jl, http://en.wikipedia.org/]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>biopolymer metabolic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0043283
code: NPO_1013
preferred name: biopolymer metabolic process
synonym: biopolymer metabolism

biopolymer biosynthetic process
type: Class
equivalent class: Class
  intersection of: biosynthetic process
  intersection of: Restriction
    on property: has output participant
    some values from: biopolymer
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins. [source: GOC:jl, http://en.wikipedia.org/]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>biopolymer biosynthetic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0043284
code: NPO_1006
synonym: biopolymer biosynthesis
preferred name: biopolymer biosynthetic process
synonym: biopolymer formation
synonym: biopolymer synthesis

negative regulation of molecular function
type: Class
equivalent class: Restriction
  on property: negatively regulates
  some values from: molecular function
subclass of: regulation of molecular function
subclass of: Restriction
  on property: realizes
  some values from: inhibitor role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>negative regulation of molecular function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0044092
code: NPO_1654
preferred name: negative regulation of molecular function

positive regulation of molecular function
type: Class
equivalent class: Restriction
  on property: positively regulates
  some values from: molecular function
subclass of: regulation of molecular function
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>positive regulation of molecular function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0044093
code: NPO_1644
preferred name: positive regulation of molecular function

cellular metabolic process
type: Class
equivalent class: Class
  intersection of: metabolic process
  intersection of: Restriction
    on property: has participant
    some values from: cell
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways by which individual cells transform chemical substances. [source: GOC:go_curators]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cellular metabolic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0044237
code: NPO_1011
preferred name: cellular metabolic process
synonym: cellular metabolism

cellular biosynthetic process
type: Class
equivalent class: Class
  intersection of: biosynthetic process
  intersection of: Restriction
    on property: has participant
    some values from: cell
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. [source: GOC:jl]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cellular biosynthetic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0044249
code: NPO_1010
preferred name: cellular biosynthetic process

positive regulation of DNA replication
type: Class
equivalent class: Restriction
  on property: positively regulates
  some values from: DNA replication
subclass of: positive regulation of biological process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases the frequency, rate or extent of DNA replication.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>positive regulation of DNA replication</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0045740
code: NPO_1648
synonym: activation of DNA replication
preferred name: positive regulation of DNA replication
synonym: stimulation of DNA replication
synonym: up regulation of DNA replication
synonym: up-regulation of DNA replication
synonym: upregulation of DNA replication

positive regulation of angiogenesis
type: Class
equivalent class: Restriction
  on property: positively regulates
  some values from: angiogenesis
subclass of: positive regulation of biological process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>positive regulation of angiogenesis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0045766
code: NPO_1645
preferred name: positive regulation of angiogenesis

positive regulation of cell adhesion
type: Class
equivalent class: Restriction
  on property: positively regulates
  some values from: cell adhesion
subclass of: positive regulation of biological process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases the frequency, rate or extent of cell adhesion.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>positive regulation of cell adhesion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0045785
code: NPO_1643
preferred name: positive regulation of cell adhesion

negative regulation of mitosis
type: Class
equivalent class: Restriction
  on property: negatively regulates
  some values from: mitosis
subclass of: negative regulation of biological process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>negative regulation of mitosis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0045839
code: NPO_1640
synonym: down regulation of mitosis
synonym: down-regulation of mitosis
synonym: downregulation of mitosis
synonym: inhibition of mitosis
preferred name: negative regulation of mitosis

positive regulation of mitosis
type: Class
equivalent class: Restriction
  on property: positively regulates
  some values from: mitosis
subclass of: positive regulation of biological process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases the frequency, rate or extent of mitosis.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>positive regulation of mitosis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0045840
code: NPO_1639
synonym: activation of mitosis
preferred name: positive regulation of mitosis
synonym: stimulation of mitosis
synonym: up regulation of mitosis
synonym: up-regulation of mitosis
synonym: upregulation of mitosis

negative regulation of DNA-dependent transcription
type: Class
equivalent class: Restriction
  on property: negatively regulates
  some values from: DNA-dependent transcription
subclass of: negative regulation of biological process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops, prevents or reduces the frequency, rate or extent of DNA-dependent transcription.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>negative regulation of DNA-dependent transcription</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0045892
code: NPO_1652
synonym: down regulation of DNA-dependent transcription
synonym: down-regulation of DNA-dependent transcription
synonym: downregulation of DNA-dependent transcription
synonym: inhibition of DNA-dependent transcription
preferred name: negative regulation of DNA-dependent transcription

positive regulation of DNA-dependent transcription
type: Class
equivalent class: Restriction
  on property: positively regulates
  some values from: DNA-dependent transcription
subclass of: positive regulation of biological process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases the frequency, rate or extent of DNA-dependent transcription.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>positive regulation of DNA-dependent transcription</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0045893
code: NPO_1651
synonym: activation of DNA-dependent transcription
preferred name: positive regulation of DNA-dependent transcription
synonym: stimulation of DNA-dependent transcription
synonym: up regulation of DNA-dependent transcription
synonym: up-regulation of DNA-dependent transcription
synonym: upregulation of DNA-dependent transcription

folic acid metabolic process
type: Class
subclass of: cellular metabolic process
subclass of: Restriction
  on property: has participant
  some values from: folic acid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>folic acid metabolic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0046655
code: NPO_1629
synonym: folate metabolic process
synonym: folate metabolism
preferred name: folic acid metabolic process
synonym: folic acid metabolism

beta-tubulin binding
type: Class
subclass of: tubulin binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with the microtubule constituent protein beta-tubulin. [source: GOC:krc]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>beta-tubulin binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0048487
code: NPO_793
preferred name: beta-tubulin binding

positive regulation of biological process
type: Class
equivalent class: Restriction
  on property: positively regulates
  some values from: biological process
subclass of: regulation of biological process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases the frequency, rate or extent of biological process.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>positive regulation of biological process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0048518
code: NPO_1638
preferred name: positive regulation of biological process

negative regulation of biological process
type: Class
equivalent class: Restriction
  on property: negatively regulates
  some values from: biological process
subclass of: regulation of biological process
subclass of: Restriction
  on property: realizes
  some values from: inhibitor role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops, prevents or reduces the frequency, rate or extent of a biological process.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>negative regulation of biological process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0048519
code: NPO_1647
preferred name: negative regulation of biological process

anatomical structure formation
type: Class
subclass of: developmental process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. [source: GOC:dph, GOC:jic]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>anatomical structure formation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0048646
code: NPO_993
preferred name: anatomical structure formation
synonym: formation of an anatomical structure

regulation of biological process
type: Class
equivalent class: Restriction
  on property: regulates
  some values from: biological process
subclass of: process
subclass of: Restriction
  on property: realizes
  some values from: regulator role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>regulation of biological process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0050789
code: NPO_1637
preferred name: regulation of biological process
synonym: regulation of physiological process

cell division
type: Class
subclass of: cellular process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The process resulting in the physical partitioning and separation of a cell into daughter cells. [source: GOC:go_curators]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cell division</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0051301
code: NPO_545
preferred name: cell division

hormone receptor binding
type: Class
subclass of: receptor binding
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with a receptor for hormones. [source: GOC:ai]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hormone receptor binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0051427
code: NPO_499
preferred name: hormone receptor binding

regulation of molecular function
type: Class
equivalent class: Restriction
  on property: regulates
  some values from: molecular function
subclass of: process
subclass of: Restriction
  on property: realizes
  some values from: regulator role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>regulation of molecular function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0065009
code: NPO_1653
preferred name: regulation of molecular function

cellular necrosis
type: Class
subclass of: cell death
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cellular necrosis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: GO:0070265
code: NPO_1369
preferred name: cellular necrosis
synonym: necrosis

mobility
type: Class
subclass of: realizable_entity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity inhering in an object by virtue of its ability to move or be moved freely.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>mobility</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1314
DB xref ID: PATO:0000004
preferred name: mobility

velocity
type: Class
subclass of: rate
subclass of: Restriction
  on property: has unit of measure
  some values from: unit of velocity
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity inhering in an object by virtue of the rate of change of its position.</ncicp:def-definition><ncicp:Definition_Review_Date>100429</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>velocity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1316
DB xref ID: PATO:0000008
synonym: speed
preferred name: velocity

frequency
type: Class
subclass of: rate
subclass of: Restriction
  on property: has unit of measure
  some values from: frequency unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The rate at which an event occurs or is repeated over a particular period of time.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>frequency</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1330
DB xref ID: PATO:0000044
preferred name: frequency

size
type: Class
subclass of: independent general individual quality
subclass of: Restriction
  on property: quality of
  some values from: material entity
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a bearer by virtue of its physical magnitude.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>size</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1225
DB xref ID: PATO:0000117
preferred name: size

height
type: Class
subclass of: 1-D extent
subclass of: Restriction
  on property: has unit of measure
  some values from: length unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 1-D extent quality which is equal to the vertical dimension of extension.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>height</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1229
DB xref ID: PATO:0000119
preferred name: height

length
type: Class
subclass of: 1-D extent
subclass of: Restriction
  on property: has unit of measure
  some values from: length unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 1-D extent quality which is equal to the distance between two points.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>length</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1227
DB xref ID: PATO:0000122
preferred name: length

mass
type: Class
subclass of: independent general individual quality
subclass of: Restriction
  on property: quality of
  some values from: material entity
subclass of: Restriction
  on property: has unit of measure
  some values from: mass unit
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality that inheres in a bearer in proportion to the amount of matter it contains. It is the property of a substance that causes it to have weight in a gravitational field.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>mass</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1169
DB xref ID: PATO:0000125
preferred name: mass

weight
type: Class
subclass of: force
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A force inhering in an object with mass near a gravitational body.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>weight</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1218
DB xref ID: PATO:0000128
preferred name: weight

temperature
type: Class
subclass of: independent general individual quality
subclass of: Restriction
  on property: has unit of measure
  some values from: temperature unit
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality of the thermal energy of a system.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>temperature</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1287
DB xref ID: PATO:0000146
preferred name: temperature

viability
type: Class
subclass of: realizable_entity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity inhering in a bearer or a population, by virtue of the bearer's ability or inability to survive and develop normally or the number of surviving individuals in a given population.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>viability</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1342
DB xref ID: PATO:0000169
preferred name: viability

photosensitive
type: Class
subclass of: photosensitivity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition inhering in a bearer by virtue of its exhibiting photosensitivity.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>photosensitive</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1348
DB xref ID: PATO:0000547
preferred name: photosensitive

thickness
type: Class
subclass of: 1-D extent
subclass of: Restriction
  on property: has unit of measure
  some values from: length unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 1-D extent quality which is equal to the dimension through an object as opposed to its length or width.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>thickness</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1230
DB xref ID: PATO:0000915
preferred name: thickness

volume
type: Class
subclass of: 3-D extent
subclass of: Restriction
  on property: has unit of measure
  some values from: volume unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 3-D extent quality of the amount of 3-dimensional space an object occupies.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>volume</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1238
DB xref ID: PATO:0000918
preferred name: volume

width
type: Class
subclass of: 1-D extent
subclass of: Restriction
  on property: has unit of measure
  some values from: length unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 1-D extent quality which is equal to the distance from one side of an object to another side which is opposite.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>width</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1231
DB xref ID: PATO:0000921
synonym: breadth
preferred name: width

photosensitivity
type: Class
subclass of: sensitivity to stimulus
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition inhering to the bearer by virtue of its sensitivity to the action of radiant energy.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>photosensitivity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1347
DB xref ID: PATO:0000927
preferred name: photosensitivity

physical quality
type: Class
subclass of: quality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality which exists through action of continuants at the physical level of organisation.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>physical quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1152
DB xref ID: PATO:0001018
preferred name: physical quality

density
type: Class
subclass of: independent general individual quality
subclass of: Restriction
  on property: quality of
  some values from: material entity
subclass of: Restriction
  on property: has unit of measure
  some values from: density unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A physical quality which inhers to the bearer by virtue of some influence exerted by its mass.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>density</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1273
DB xref ID: PATO:0001019
preferred name: density

force
type: Class
subclass of: realizable_entity
subclass of: Restriction
  on property: has unit of measure
  some values from: force unit
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity inhering in a object affecting its acceleration.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>force</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1166
DB xref ID: PATO:0001035
preferred name: force

wavelength
type: Class
subclass of: wave parameter
subclass of: Restriction
  on property: has unit of measure
  some values from: length unit
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A wave parameter which is equal to the distance between repeating units of a wave pattern.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>wavelength</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1346
DB xref ID: PATO:0001242
preferred name: wavelength

electromagnetic radiation quality
type: Class
subclass of: radiation quality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality that inheres in an object by virtue of how that object interacts with electromagnetic radiation.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>electromagnetic radiation quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1385
DB xref ID: PATO:0001291
preferred name: electromagnetic radiation quality

luminous quality
type: Class
subclass of: optical quality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A scalar optical quality which obtains by the magnitude of the light emitted by the bearer.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>luminous quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1387
DB xref ID: PATO:0001296
preferred name: luminous quality

optical quality
type: Class
subclass of: electromagnetic radiation quality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An EM radiation quality in which the EM radiation is within the fiat range of the spectrum visible deemed to be light.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>optical quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1386
DB xref ID: PATO:0001300
preferred name: optical quality

area
type: Class
subclass of: 2-D extent
subclass of: Restriction
  on property: has unit of measure
  some values from: area unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 2-D extent inhering in a bearer by virtue of its two dimensional extent.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>area</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1234
DB xref ID: PATO:0001323
preferred name: area

diameter
type: Class
subclass of: length
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality which is equal to the length of any straight line segment that passes through the center of a circle and whose endpoints are on the circular boundary.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>diameter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1228
DB xref ID: PATO:0001334
preferred name: diameter

mass density
type: Class
subclass of: density
subclass of: Restriction
  on property: has unit of measure
  some values from: mass density unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A density quality which is equal to the mass exerting an influence on a given volume.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>mass density</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1274
DB xref ID: PATO:0001353
preferred name: mass density

membrane potential
type: Class
subclass of: electric potential
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a cell's plasma membrane by virtue of the electrical potential difference across it.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>membrane potential</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1301
DB xref ID: PATO:0001462
preferred name: membrane potential

electric potential
type: Class
subclass of: realizable_entity
subclass of: Restriction
  on property: has unit of measure
  some values from: electric potential difference unit
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity that is equal to the potential energy per unit charge associated with a static (time-invariant) electric field, also called the electrostatic potential.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>electric potential</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1300
DB xref ID: PATO:0001464
preferred name: electric potential
synonym: electrostatic potential

sound quality
type: Class
subclass of: quality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a bearer by virtue of vibration, as perceived by the sense of hearing.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>sound quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1349
DB xref ID: PATO:0001519
preferred name: sound quality

frequency of sound wave
type: Class
subclass of: wave frequency
subclass of: Restriction
  on property: has unit of measure
  some values from: frequency unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The frequency of transmitted vibrations.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>frequency of sound wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1350
DB xref ID: PATO:0001520
synonym: frequency of sound
preferred name: frequency of sound wave

speed of sound wave
type: Class
subclass of: wave speed
subclass of: Restriction
  on property: has unit of measure
  some values from: unit of velocity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The speed at which sound travels in a given medium under specified conditions.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>speed of sound wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1352
DB xref ID: PATO:0001522
synonym: speed of sound
preferred name: speed of sound wave
synonym: velocity of sound

wavelength of sound
type: Class
subclass of: wavelength
subclass of: Restriction
  on property: has unit of measure
  some values from: length unit
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>The quotient of the speed of a sound wave divided by its frequency.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>wavelength of sound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1353
DB xref ID: PATO:0001523
preferred name: wavelength of sound

depth
type: Class
subclass of: 1-D extent
subclass of: Restriction
  on property: has unit of measure
  some values from: length unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 1-D extent downward or backward or inward.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>depth</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1232
DB xref ID: PATO:0001595
preferred name: depth

specific volume
type: Class
subclass of: independent specific individual quality
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality of the amount of 3-dimensional space a mass of substance occupies.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>specific volume</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1240
DB xref ID: PATO:0001679
comment: The reciprocal of density.
preferred name: specific volume

molar volume
type: Class
subclass of: independent specific individual quality
subclass of: Restriction
  on property: has unit of measure
  some values from: molar volume unit
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality of the amount of 3-dimensional space a homogeneous substance containing 6.02 x 1023 atoms or molecules occupies.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>molar volume</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1239
DB xref ID: PATO:0001680
preferred name: molar volume

molar mass
type: Class
subclass of: independent specific individual quality
subclass of: Restriction
  on property: has unit of measure
  some values from: molar mass unit
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality that inheres in a homogeneous substance containing 6.02 x 1023 atoms or molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>molar mass</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1170
DB xref ID: PATO:0001681
preferred name: molar mass

magnetism
type: Class
subclass of: realizable_entity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity which is a property inhering in a material entity by virtue of its ability to exert an attractive or repulsive force on other material entities.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>magnetism</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1157
DB xref ID: PATO:0001682
preferred name: magnetism

magnetic
type: Class
subclass of: magnetism
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A magnetic behavior exhibited 1) by materials which produce magnetic fields to exert attractive or repulsive forces on other materials or 2) by materials which become magnetized when exposed to a magnetic field.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>magnetic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_406
DB xref ID: PATO:0001685
preferred name: magnetic
synonym: magnetic behavior

1-D extent
type: Class
subclass of: size
preferred name: 1-D extent
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in an bearer by virtue of its extension in one dimension.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>1-D extent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1226
DB xref ID: PATO:0001708

2-D extent
type: Class
subclass of: size
preferred name: 2-D extent
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in an bearer by virtue of its extenstion in two dimensions.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>2-D extent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1233
DB xref ID: PATO:0001709

3-D extent
type: Class
subclass of: size
preferred name: 3-D extent
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in an bearer by virtue of its extenstion in three dimensions.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>3-D extent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1237
DB xref ID: PATO:0001710

perimeter
type: Class
subclass of: 2-D extent
subclass of: Restriction
  on property: has unit of measure
  some values from: length unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 2-D extent quality which is equal to the distance around a given two-dimensional object.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>perimeter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1236
DB xref ID: PATO:0001711
preferred name: perimeter

radiation quality
type: Class
subclass of: physical quality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality that inheres in an object by virtue of how that object interacts with radiation.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>radiation quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1381
DB xref ID: PATO:0001739
preferred name: radiation quality

acidity
type: Class
subclass of: dependent specific individual quality
subclass of: Restriction
  on property: quality of
  some values from: Class
    union of: medium
    union of: suspension
    union of: liquid
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in an entity by virtue of it containing acid (hydrogen ions).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>acidity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1197
DB xref ID: PATO:0001842
preferred name: acidity

hydrophobic
type: Class
subclass of: realizable_entity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable property which inheres in a molecule that lacks affinity for water molecules, or has a tendency to repel or not to mix with water molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydrophobic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_399
DB xref ID: PATO:0001885
preferred name: hydrophobic
synonym: hydrophobicity

hydrophilic
type: Class
subclass of: realizable_entity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable property which inheres in a molecule that has a strong affinity to a water molecule, or has a tendency to mix with or wetted by water molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hydrophilic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_204
DB xref ID: PATO:0001887
preferred name: hydrophilic
synonym: hydrophilicity

movement quality
type: Class
subclass of: physical quality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a bearer by virtue of its participation in movement.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>movement quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1313
DB xref ID: PATO:0001906
preferred name: movement quality

chemical reaction
type: Class
subclass of: process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process involving the interconversion of chemical species.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>chemical reaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1596
DB xref ID: REX:0000002
preferred name: chemical reaction

photoluminescence
type: Class
subclass of: luminescence
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Luminescence arising from photoexcitation.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>photoluminescence</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1400
DB xref ID: REX:0000038
preferred name: photoluminescence

fluorescence
type: Class
subclass of: photoluminescence
subclass of: Restriction
  on property: realizes
  some values from: fluorescent
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Photoluminescence which occurs essentially only during the irradiation of a substance by electromagnetic radiation.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fluorescence</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1401
DB xref ID: REX:0000043
preferred name: fluorescence

phosphorescence
type: Class
subclass of: photoluminescence
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A photoluminescence which is long-lived compared to fluorescence, and involves change in spin multiplicity, typically from triplet to singlet or vice versa. The luminescence from a quartet state to a doublet state is also phosphorescence. [source: http://goldbook.iupac.org/P04569.htm]</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>phosphorescence</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1444
DB xref ID: REX:0000044
preferred name: phosphorescence

inhibition
type: Class
equivalent class: Restriction
  on property: realizes
  some values from: inhibitor role
subclass of: chemical reaction
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The decrease in rate of reaction brought about by the addition of a substance (inhibitor), by virtue of its effect on the concentration of a reactant, catalyst or reaction intermediate.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>inhibition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1631
DB xref ID: REX_0000218
preferred name: inhibition

luminescence
type: Class
subclass of: emission
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Spontaneous emission of radiation from an electronically or vibrationally excited species not in thermal equilibrium with its environment.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>luminescence</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1399
DB xref ID: REX:0000290
preferred name: luminescence

chemiluminescence
type: Class
subclass of: luminescence
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Luminescence resulting from a chemical reaction.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>chemiluminescence</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1402
DB xref ID: REX:0000294
preferred name: chemiluminescence

emission
type: Class
subclass of: process
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Radioactive deactivation of an excited state of a material entity by which energy is transferred from the material entity to an electromagnetic field.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>emission</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1398
DB xref ID: REX:0000303
preferred name: emission

unit of measurement
type: Class
subclass of: generically_dependent_continuant
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quantitative measure of a property, which is a quantity chosen as a standard measure in terms of which other quantities (measured numerical values) are expressed in.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>unit of measurement</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1153
DB xref ID: UO:0000000
synonym: unit
preferred name: unit of measurement

length unit
type: Class
subclass of: unit of measurement
subclass of: Restriction
  on property: unit of
  some values from: height
subclass of: Restriction
  on property: unit of
  some values from: width
subclass of: Restriction
  on property: unit of
  some values from: length
subclass of: Restriction
  on property: unit of
  some values from: thickness
subclass of: Restriction
  on property: unit of
  some values from: depth
subclass of: Restriction
  on property: unit of
  some values from: perimeter
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the distance between two points.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>length unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1241
DB xref ID: UO:0000001
preferred name: length unit
synonym: unit of length

mass unit
type: Class
subclass of: unit of measurement
subclass of: Restriction
  on property: unit of
  some values from: mass
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of measurement which is a standard measure of the amount of matter/energy of a physical object.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>mass unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1172
DB xref ID: UO:0000002
preferred name: mass unit
synonym: unit of mass

time unit
type: Class
subclass of: unit of measurement
subclass of: Restriction
  on property: unit of
  some values from: time quality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A base unit which is a standard measure of the dimension in which events occur in sequence.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>time unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1275
DB xref ID: UO:0000003
preferred name: time unit
synonym: unit of time

temperature unit
type: Class
subclass of: unit of measurement
subclass of: Restriction
  on property: unit of
  some values from: temperature
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the average kinetic energy of the particles in a sample of matter.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>temperature unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1288
DB xref ID: UO:0000005
preferred name: temperature unit
synonym: unit of temperature

substance unit
type: Class
subclass of: unit of measurement
subclass of: Restriction
  on property: unit of
  some values from: amount of substance
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A base unit which is a standardized quantity of an element or compound with uniform composition.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>substance unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1216
DB xref ID: UO:0000006
preferred name: substance unit
synonym: unit of amount of substance

meter
type: Class
subclass of: length unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A length unit which is equal to the length of the path traveled by light in vacuum during a time interval of 1/299 792 458 of a second.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>meter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1242
DB xref ID: UO:0000008
symbol: m
preferred name: meter

kilogram
type: Class
subclass of: mass unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass unit which is equal to the mass of the International Prototype Kilogram kept by the BIPM at Svres, France.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>kilogram</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1179
DB xref ID: UO:0000009
symbol: kg
preferred name: kilogram

second
type: Class
subclass of: time unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to the duration of 9 192 631 770 periods of the radiation corresponding to the transition between the two hyperfine levels of the ground state of the caesium 133 atom.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>second</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1276
DB xref ID: UO:0000010
symbol: s
preferred name: second

Kelvin
type: Class
subclass of: temperature unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thermodynamic temperature unit which is equal to the fraction 1/273.16 of the thermodynamic temperature of the triple point of water.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Kelvin</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
symbol: K
preferred name: Kelvin
code: NPO_1291
DB xref ID: UO:0000012

mole
type: Class
subclass of: substance unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A substance unit which is equal to the amount of substance of a molecular system which contains as many elementary entities as there are atoms in 0.012 kilogram of carbon 12.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>mole</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1221
DB xref ID: UO:0000013
symbol: mol
preferred name: mole

centimeter
type: Class
subclass of: length unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A length unit which is equal to one hundredth of a meter or 10^[-2] m.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>centimeter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1243
DB xref ID: UO:0000015
preferred name: centimeter
symbol: cm

millimeter
type: Class
subclass of: length unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A length unit which is equal to one thousandth of a meter or 10^[-3] m.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>millimeter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1244
DB xref ID: UO:0000016
preferred name: millimeter
symbol: mm

micrometer
type: Class
subclass of: length unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A length unit which is equal to one millionth of a meter or 10^[-6] m.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>micrometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1245
DB xref ID: UO:0000017
preferred name: micrometer
symbol: µm

nanometer
type: Class
subclass of: length unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A length unit which is equal to one thousandth of one millionth of a meter or 10^[-9] m.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1246
DB xref ID: UO:0000018
preferred name: nanometer
symbol: nm

angstrom
type: Class
subclass of: length unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A length unit which is equal to 10 [-10] m.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>angstrom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
symbol: A
code: NPO_1247
DB xref ID: UO:0000019
preferred name: angstrom

gram
type: Class
subclass of: mass unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass unit which is equal to one thousandth of a kilogram or 10^[-3] kg.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gram</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1180
DB xref ID: UO:0000021
symbol: g
preferred name: gram

milligram
type: Class
subclass of: mass unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass unit which is equal to one thousandth of a gram or 10^[-3] g.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>milligram</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1181
DB xref ID: UO:0000022
symbol: mg
preferred name: milligram

microgram
type: Class
subclass of: mass unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass unit which is equal to one millionth of a gram or 10^[-6] g.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>microgram</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1182
DB xref ID: UO:0000023
preferred name: microgram
symbol: µg

nanogram
type: Class
subclass of: mass unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass unit which is equal to one thousandth of one millionth of a gram or 10^[-9] g.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanogram</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1183
DB xref ID: UO:0000024
preferred name: nanogram
symbol: ng

degree celsius
type: Class
subclass of: temperature unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A temperature unit on the Celsius scale based on which the freezing point of water is 0 degrees Celsius and the boiling point is 100 degree Celsius at standard conditions. Celsius scale has its zero at 273.15 K.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>degree celsius</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1289
DB xref ID: UO:0000027
symbol: deg. C
preferred name: degree celsius

millisecond
type: Class
subclass of: time unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to one thousandth of a second or 10^[-3] s.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>millisecond</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1277
DB xref ID: UO:0000028
preferred name: millisecond
synonym: ms

microsecond
type: Class
subclass of: time unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to one millionth of a second or 10^[-6] s.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>microsecond</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1278
DB xref ID: UO:0000029
preferred name: microsecond
symbol: µs

minute
type: Class
subclass of: time unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time derived unit which is equal to 60 seconds.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>minute</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1281
DB xref ID: UO:0000031
synonym: min
preferred name: minute

hour
type: Class
subclass of: time unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to 3600 seconds or 60 minutes.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hour</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1282
DB xref ID: UO:0000032
symbol: h
preferred name: hour

day
type: Class
subclass of: time unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to 24 hours.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>day</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1283
DB xref ID: UO:0000033
preferred name: day

week
type: Class
subclass of: time unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to 7 days.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>week</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1284
DB xref ID: UO:0000034
preferred name: week
symbol: wk

month
type: Class
subclass of: time unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is approximately equal to the length of time of one of cycle of the moon's phases which is taken to be equal to 30 days.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>month</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1178
DB xref ID: UO:0000035
preferred name: month

year
type: Class
subclass of: time unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to 12 months.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>year</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1177
DB xref ID: UO:0000036
symbol: y
preferred name: year

micromole
type: Class
subclass of: substance unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A substance unit equal to a millionth of a mol or 10^[-6] mol.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>micromole</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1223
DB xref ID: UO:0000039
preferred name: micromole
symbol: µmol

millimole
type: Class
subclass of: substance unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A substance unit equal to a thousandth of a mol or 10^[-3] mol.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>millimole</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1222
DB xref ID: UO:0000040
preferred name: millimole
symbol: mmol

nanomole
type: Class
subclass of: substance unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A substance unit equal to one thousandth of one millionth of a mole or 10^[-9] mol.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanomole</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1224
DB xref ID: UO:0000041
preferred name: nanomole
symbol: nmol

area unit
type: Class
subclass of: unit of measurement
subclass of: Restriction
  on property: unit of
  some values from: area
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the amount of a 2-dimensional surface.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>area unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1248
DB xref ID: UO:0000047
preferred name: area unit
synonym: unit of area

concentration unit
type: Class
subclass of: unit of measurement
subclass of: Restriction
  on property: unit of
  some values from: concentration
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which represents a standard measurement of how much of a given substance there is mixed with another substance.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>concentration unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1168
DB xref ID: UO:0000051
preferred name: concentration unit
synonym: unit of concentration

mass density unit
type: Class
subclass of: density unit
subclass of: Restriction
  on property: unit of
  some values from: mass density
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A density unit which is a standard measure of the mass of a substance in a given volume.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>mass density unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1264
DB xref ID: UO:0000052
preferred name: mass density unit
synonym: unit of mass density

molar mass unit
type: Class
subclass of: unit of measurement
subclass of: Restriction
  on property: unit of
  some values from: molar mass
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the mass of a homogeneous substance containing 6.02 x 1023 atoms or molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>molar mass unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1184
DB xref ID: UO:0000055
preferred name: molar mass unit
synonym: unit of molar mass

molar volume unit
type: Class
subclass of: unit of measurement
subclass of: Restriction
  on property: unit of
  some values from: molar volume
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the volume of a homogeneous substance containing 6.02 x 1023 atoms or molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>molar volume unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1260
DB xref ID: UO:0000056
preferred name: molar volume unit
synonym: unit of molar volume

unit of velocity
type: Class
subclass of: unit of measurement
subclass of: Restriction
  on property: unit of
  some values from: velocity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A standard measure of the rate of movement. Speed is measured in the same physical units of measurement as velocity, but does not contain the element of direction that velocity has. Speed is thus the magnitude component of velocity.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>unit of velocity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1328
DB xref ID: UO:0000060
synonym: unit of speed
preferred name: unit of velocity

unit of molarity
type: Class
subclass of: concentration unit
subclass of: Restriction
  on property: unit of
  some values from: molarity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A concentration unit which is a standard measure of the number of moles of a given substance per liter of solution.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>unit of molarity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1187
DB xref ID: UO:0000061
preferred name: unit of molarity

molar
type: Class
subclass of: unit of molarity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of concentration which expresses a concentration of 1 mole of solute per liter of solution (mol/L).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>molar</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
symbol: M
code: NPO_1207
DB xref ID: UO:0000062
preferred name: molar

millimolar
type: Class
subclass of: unit of molarity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of molarity which is equal to one thousandth of a molar or 10^[-3] M.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>millimolar</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1208
DB xref ID: UO:0000063
symbol: mM
preferred name: millimolar

micromolar
type: Class
subclass of: unit of molarity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of molarity which is equal to one millionth of a molar or 10^[-6] M.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>micromolar</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1209
DB xref ID: UO:0000064
preferred name: micromolar
symbol: µM

nanomolar
type: Class
subclass of: unit of molarity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of molarity which is equal to one thousandth of one millionth of a molar or 10^[-9] M.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanomolar</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1210
DB xref ID: UO:0000065
symbol: nM
preferred name: nanomolar

unit of molality
type: Class
subclass of: concentration unit
subclass of: Restriction
  on property: unit of
  some values from: molality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A concentration unit which is a standard measure of the number of moles of a given solute per kilogram of solvent.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>unit of molality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1188
DB xref ID: UO:0000067
preferred name: unit of molality

molal
type: Class
subclass of: unit of molality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of concentration which expresses a concentration of a solution of 1 mole per kilogram of solvent (mol/kg).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>molal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1211
DB xref ID: UO:0000068
symbol: mol/kg
preferred name: molal

millimolal
type: Class
subclass of: unit of molality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molality unit which is equal to one thousandth of a molal or 10^[-3] m.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>millimolal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1212
DB xref ID: UO:0000069
preferred name: millimolal
symbol: mmol/kg

micromolal
type: Class
subclass of: unit of molality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molality unit which is equal to one millionth of a molal or 10^[-6] m.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>micromolal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1213
DB xref ID: UO:0000070
preferred name: micromolal
symbol: µmol/kg

nanomolal
type: Class
subclass of: unit of molality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molality unit which is equal to one thousandth of one millionth of a molal or 10^[-9] m.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanomolal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1214
DB xref ID: UO:0000071
preferred name: nanomolal
symbol: nmol/kg

unit of normality
type: Class
subclass of: concentration unit
subclass of: Restriction
  on property: unit of
  some values from: normality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A concentration unit which is a standard measure of the number gram equivalents of solute per liter of solution.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>unit of normality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1189
DB xref ID: UO:0000074
preferred name: unit of normality

normal
type: Class
subclass of: unit of normality
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of concentration which is one gram equivalent of a solute per liter of solution. A gram equivalent weight or equivalent is a measure of the reactive capacity of a given molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>normal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
symbol: N
code: NPO_1215
DB xref ID: UO:0000075
preferred name: normal

square meter
type: Class
subclass of: area unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An area unit which is equal to an area enclosed by a square with sides each 1 meter long.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>square meter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1249
DB xref ID: UO:0000080
symbol: m^[2]
preferred name: square meter

square centimeter
type: Class
subclass of: area unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An area unit which is equal to one thousand of square meter or 10^[-3] m^[2].</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>square centimeter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1250
DB xref ID: UO:0000081
symbol: cm^[2]
preferred name: square centimeter

square millimeter
type: Class
subclass of: area unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An area unit which is equal to one millionth of a square meter or 10^[-6] m^[2].</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>square millimeter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1251
DB xref ID: UO:0000082
symbol: mm^[2]
preferred name: square millimeter

kilogram per cubic meter
type: Class
subclass of: mass density unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in kilograms divided by the volume in cubic meters.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>kilogram per cubic meter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1269
DB xref ID: UO:0000083
symbol: kg/m^[3]
preferred name: kilogram per cubic meter

gram per cubic centimeter
type: Class
subclass of: mass density unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in grams divided by the volume in cubic centimeters.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gram per cubic centimeter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1270
DB xref ID: UO:0000084
symbol: g/cm^[3]
preferred name: gram per cubic centimeter
synonym: grams per cubic centimeter

kilogram per mole
type: Class
subclass of: molar mass unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molar mass unit which is equal to one kilogram of mass of one mole of chemical element or chemical compound.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>kilogram per mole</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1185
DB xref ID: UO:0000087
symbol: kg/mol
preferred name: kilogram per mole

gram per mole
type: Class
subclass of: molar mass unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molar mass unit which is equal to one gram of mass of one mole of chemical element or chemical compound.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gram per mole</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1186
DB xref ID: UO:0000088
symbol: g/mol
preferred name: gram per mole

cubic meter per mole
type: Class
subclass of: molar volume unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molar volume unit which is equal to 1 cubic meter occupied by one mole of a substance in the form of a solid, liquid, or gas.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cubic meter per mole</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1261
DB xref ID: UO:0000089
preferred name: cubic meter per mole
symbol: m^[3]/mol

cubic centimeter per mole
type: Class
subclass of: molar volume unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molar volume unit which is equal to 1 cubic centimeter occupied by one mole of a substance in the form of a solid, liquid, or gas.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cubic centimeter per mole</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1262
DB xref ID: UO:0000090
symbol: cm^[3]/mol
preferred name: cubic centimeter per mole

meter per second
type: Class
subclass of: unit of velocity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A speed/velocity unit which is equal to the speed of an object traveling 1 meter distance in one second.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>meter per second</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1329
DB xref ID: UO:0000094
symbol: m/s
preferred name: meter per second

volume unit
type: Class
subclass of: unit of measurement
subclass of: Restriction
  on property: unit of
  some values from: volume
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the amount of space occupied by any substance, whether solid, liquid, or gas.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>volume unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1253
DB xref ID: UO:0000095
synonym: unit of volume
preferred name: volume unit

cubic meter
type: Class
subclass of: volume unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A volume unit which is equal to the volume of a cube with edges one meter in length. One cubic meter equals to 1000 liters.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cubic meter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1254
DB xref ID: UO:0000096
preferred name: cubic meter
symbol: m^[3]

cubic centimeter
type: Class
subclass of: volume unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A volume unit which is equal to one millionth of a cubic meter or 10^[-9] m^[3], or to 1 ml.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cubic centimeter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1255
DB xref ID: UO:0000097
symbol: cc
symbol: cm^[3]
preferred name: cubic centimeter

milliliter
type: Class
subclass of: volume unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A volume unit which is equal to one thousandth of a liter or 10^[-3] L, or to 1 cubic centimeter.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>milliliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1256
DB xref ID: UO:0000098
symbol: mL
preferred name: milliliter

liter
type: Class
subclass of: volume unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A volume unit which is equal to one thousandth of a cubic meter or 10^[-3] m^[3], or to 1 decimeter.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>liter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
symbol: L
code: NPO_1257
DB xref ID: UO:0000099
preferred name: liter

microliter
type: Class
subclass of: volume unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A volume unit which is equal to one millionth of a liter or 10^[-6] L.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>microliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1258
DB xref ID: UO:0000101
preferred name: microliter
symbol: µL

nanoliter
type: Class
subclass of: volume unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A volume unit which is equal to one thousandth of one millionth of a liter or 10^[-9] L.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanoliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1259
DB xref ID: UO:0000102
symbol: nL
preferred name: nanoliter

frequency unit
type: Class
subclass of: unit of measurement
subclass of: Restriction
  on property: unit of
  some values from: frequency
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the number of repetitive actions in a particular time.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>frequency unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1331
DB xref ID: UO:0000105
preferred name: frequency unit

hertz
type: Class
subclass of: frequency unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A frequency unit which is equal to 1 complete cycle of a recurring phenomenon in 1 second.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>hertz</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
symbol: Hz
code: NPO_1332
DB xref ID: UO:0000106
preferred name: hertz

force unit
type: Class
subclass of: unit of measurement
subclass of: Restriction
  on property: unit of
  some values from: force
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of measurement for the force applied to accelerate a mass (an amount of matter).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>force unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1173
DB xref ID: UO:0000107
preferred name: force unit
synonym: unit of force

Newton
type: Class
subclass of: force unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A force unit which is equal to the force required to cause an acceleration of 1m/s2 of a mass of 1 Kg in the direction of the force.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Newton</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
symbol: N
code: NPO_1174
preferred name: Newton
DB xref ID: UO:0000108

nanosecond
type: Class
subclass of: time unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to one thousandth of one millionth of a second or 10^[-9] s.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>nanosecond</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1279
DB xref ID: UO:0000150
preferred name: nanosecond
symbol: ns

half life
type: Class
subclass of: realizable_entity
subclass of: Restriction
  on property: has unit of measure
  some values from: time unit
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity which inheres in a chemical or element which represents the period over which the amount, activity or concentration of a specified chemical or element falls to half its original amount, activity or concentration. The realization is the observation of change in the concentration, activity or amount of the bearer.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>half life</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1280
DB xref ID: UO:0000152
preferred name: half life
synonym: t1/2

percent mass per mass
type: Class
subclass of: percent
symbol: % w/w
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A percentage unit of concentration which denotes the mass of a substance in a mixture as a percentage of the mass of the entire mixture.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>percent mass per mass</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C48528
code: NPO_1324
DB xref ID: UO:0000163
synonym: mass percentage
preferred name: percent mass per mass
synonym: percent weight per weight
synonym: percent weight/weight
symbol: w/w %
synonym: weight-weight percentage

percent mass per volume
type: Class
subclass of: percent
symbol: % w/v
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A percentage unit concentration which denotes the mass of the substance in a mixture as a percentage of the volume of the entire mixture.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>percent mass per volume</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C48527
code: NPO_1326
DB xref ID: UO:0000164
synonym: mass volume percentage
preferred name: percent mass per volume
synonym: percent weight per volume
synonym: weight-volume percentage

percent volume per volume
type: Class
subclass of: percent
symbol: % v/v
symbol: % vol
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A percentage unit concentration which denotes the volume of the solute in mL per 100 mL of the resulting solution.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>percent volume per volume</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DB xref ID: NCIT:C48571
code: NPO_1325
DB xref ID: UO:0000165
synonym: percent volume
preferred name: percent volume per volume
synonym: percent volume/volume
synonym: volume percentage

parts per notation
type: Class
subclass of: dimensionless unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dimensionless concentration notation which describes the amount of one substance in another.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>parts per notation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1319
DB xref ID: UO:0000166
preferred name: parts per notation

parts per thousand
type: Class
subclass of: parts per notation
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dimensionless concentration notation which denotes the amount of a given substance in a total amount of 1000 regardless of the units of measure as long as they are the same.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>parts per thousand</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1322
DB xref ID: UO:0000168
preferred name: parts per thousand
symbol: ppth

parts per million
type: Class
subclass of: parts per notation
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dimensionless concentration notation which denotes the amount of a given substance in a total amount of 1,000,000 regardless of the units of measure used as long as they are the same or 1 part in 10^[6].</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>parts per million</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1321
DB xref ID: UO:0000169
preferred name: parts per million
symbol: ppm

gram per milliliter
type: Class
subclass of: mass density unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in grams divided by the volume in milliliter.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gram per milliliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1265
DB xref ID: UO:0000173
symbol: g/mL
preferred name: gram per milliliter
synonym: grams per milliliter

kilogram per liter
type: Class
subclass of: mass density unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in kilograms divided by the volume in liters.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>kilogram per liter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1272
DB xref ID: UO:0000174
symbol: kg/L
preferred name: kilogram per liter
synonym: kilograms per liter

gram per liter
type: Class
subclass of: mass density unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in grams divided by the volume in liters.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>gram per liter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1271
DB xref ID: UO:0000175
symbol: g/L
preferred name: gram per liter
synonym: grams per liter

milligram per milliliter
type: Class
subclass of: mass density unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in milligrams divided by the volume in milliliters.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>milligram per milliliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1266
DB xref ID: UO:0000176
symbol: mg/mL
preferred name: milligram per milliliter
synonym: milligrams per milliliter

density unit
type: Class
subclass of: unit of measurement
subclass of: Restriction
  on property: unit of
  some values from: density
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the influence exerted by some mass.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>density unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1263
DB xref ID: UO:0000182
preferred name: density unit
synonym: unit of density

dimensionless unit
type: Class
subclass of: unit of measurement
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of measurement of which is dimensionless.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dimensionless unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1154
DB xref ID: UO:0000186
preferred name: dimensionless unit

percent
type: Class
subclass of: unit of measurement
synonym: %
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A ratio unit which denotes numbers as fractions of 100.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>percent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1323
DB xref ID: UO:0000187
preferred name: percent
synonym: percentage

count
type: Class
subclass of: dimensionless unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dimensionless unit which denotes a simple count of things.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>count</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1320
DB xref ID: UO:0000189
preferred name: count

degree Fahrenheit
type: Class
subclass of: temperature unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A temperature unit on the Fahrenheit scale in which the freezing point of water is 32 degrees Fahrenheit and the boiling point is 212 degrees at standard conditions, placing the boiling and freezing points of water 180 degrees apart. -40 degrees Fahrenheit is equal to -40 degrees Celsius.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>degree Fahrenheit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1290
DB xref ID: UO:0000195
symbol: deg. F
preferred name: degree Fahrenheit

pH
type: Class
subclass of: dependent specific individual quality
subclass of: Restriction
  on property: has unit of measure
  some values from: dimensionless unit
subclass of: Restriction
  on property: measure of
  some values from: acidity
subclass of: Restriction
  on property: quality of
  some values from: Class
    union of: medium
    union of: suspension
    union of: liquid
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>The logarithm of the reciprocal of hydrogen-ion concentration in gram atoms per liter. (source:Princeton WordNet)</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>WordNet</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1198
DB xref ID: UO:0000196
preferred name: pH

unit of cell concentration
type: Class
subclass of: concentration unit
subclass of: Restriction
  on property: unit of
  some values from: cell concentration
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A concentration unit which denotes the average cell number in a given volume.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>unit of cell concentration</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1194
DB xref ID: UO:0000200
preferred name: unit of cell concentration

cells per milliliter
type: Class
subclass of: unit of cell concentration
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of cell concentration which is equal to one cell in a volume of 1 milliliter.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>cells per milliliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1205
DB xref ID: UO:0000201
preferred name: cells per milliliter
symbol: cells/mL

electric potential difference unit
type: Class
subclass of: unit of measurement
subclass of: Restriction
  on property: unit of
  some values from: electric potential
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A standard measure of the work done per unit charge as a charge is moved between two points in an electric field.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>electric potential difference unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1295
DB xref ID: UO:0000217
preferred name: electric potential difference unit
synonym: unit of electric potential
synonym: unit of electric potential difference

volt
type: Class
subclass of: electric potential difference unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric potential difference unit which is equal to the work per unit charge. One volt is the potential difference required to move one coulomb of charge between two points in a circuit while using one joule of energy.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>volt</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1296
DB xref ID: UO:0000218
symbol: V
preferred name: volt

coulomb
type: Class
subclass of: electric charge unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electrical charge unit which is equal to the amount of charge transferred by a current of 1 ampere in 1 second.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>coulomb</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
symbol: C
code: NPO_1294
DB xref ID: UO:0000220
preferred name: coulomb

dalton
type: Class
subclass of: mass unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass unit which is equal to one twelfth of the mass of an unbound atom of the carbon-12 nuclide, at rest and in its ground state.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dalton</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
symbol: Da
code: NPO_1175
DB xref ID: UO:0000221
preferred name: dalton

kilodalton
type: Class
subclass of: mass unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass unit which is equal to one thousand daltons.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>kilodalton</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1176
DB xref ID: UO:0000222
symbol: kDa
preferred name: kilodalton

weber
type: Class
subclass of: magnetic flux unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of magnetic flux which is equal to the amount of flux that when linked with a single turn of wire for an interval of one second will induce an electromotive force of one volt.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>weber</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1160
DB xref ID: UO:0000226
symbol: V s
symbol: Wb
synonym: volt-second
preferred name: weber

Tesla
type: Class
subclass of: magnetic flux density unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of magnetic flux density which is equal to one weber per square meter.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>Tesla</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1165
symbol: T
preferred name: Tesla
DB xref ID: UO:0000228
symbol: Wb/m^[2]

volt-hour
type: Class
subclass of: magnetic flux unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of magnetic flux which is equal to 3600 Wb.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>volt-hour</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1161
DB xref ID: UO:0000229
symbol: Vh
preferred name: volt-hour

kilovolt-hour
type: Class
subclass of: magnetic flux unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of magnetic flux which is equal to one thousand volt-hours.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>kilovolt-hour</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1162
DB xref ID: UO:0000230
symbol: kV h
preferred name: kilovolt-hour

millivolt
type: Class
subclass of: electric potential difference unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric potential difference unit which is equal to one thousandth of a volt or 10^[-3] V.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>millivolt</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1297
DB xref ID: UO:0000247
symbol: mV
preferred name: millivolt

kilovolt
type: Class
subclass of: electric potential difference unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric potential difference unit which is equal to 10^[3] V.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>kilovolt</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1298
DB xref ID: UO:0000248
symbol: kV
preferred name: kilovolt

microvolt
type: Class
subclass of: electric potential difference unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric potential difference unit which is equal to one millionth of a volt or 10^[-6] V.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>microvolt</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1299
DB xref ID: UO:0000249
preferred name: microvolt
symbol: µV

decibel
type: Class
subclass of: dimensionless unit
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is an indicator of sound power per unit area.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>decibel</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1354
DB xref ID: UO:0000259
symbol: dB
preferred name: decibel

entity
type: Class
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An entity is a thing which exists in reality.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_258
preferred name: entity

continuant
type: Class
subclass of: entity
disjoint with: occurrent
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An entity [bfo:Entity] that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>continuant</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: Examples: a heart, a person, the color of a tomato, the mass of a cloud, a symphony orchestra, the disposition of blood to coagulate, the lawn and atmosphere in front of our building
code: NPO_259
preferred name: continuant
synonym: endurant
DB xref ID: snap:Continuant

dependent_continuant
type: Class
subclass of: continuant
disjoint with: independent_continuant
disjoint with: spatial_region
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A continuant [snap:Continuant] that is either dependent on one or other independent continuant [snap:IndependentContinuant] bearers or inheres in or is borne by other entities.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>dependent continuant</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: In order for a dependent continuant to exist, some other entity must exist.
code: NPO_607
preferred name: dependent continuant
DB xref ID: snap:DependentContinuant

disposition
type: Class
subclass of: realizable_entity
disjoint with: function
disjoint with: role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity [snap:RealizableEntity] that essentially causes a specific process or transformation in the object [snap:Object] in which it inheres, under specific circumstances and in conjunction with the laws of nature. A general formula for dispositions is: X (object [snap:Object] has the disposition D to (transform, initiate a process) R under conditions C.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>disposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_155
comment: Source:Robert Arp and Barry Smith "Function, Role and Disposition in Basic Formal Ontology" NATURE PROCEEDINGS, 2008.
comment: The process occurs as a result of the object's physical structure. A disposition invariably or definitely leads to a certain result given certain circumstances (if not, then the realizable entity is a tendency and not a disposition).
preferred name: disposition
DB xref ID: snap:Disposition

function
type: Class
subclass of: realizable_entity
disjoint with: role
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity [snap:RealizableEntity] the manifestation of which is an essentially end-directed activity of a continuant [snap:Continuant] entity in virtue of that continuant [snap:Continuant] entity being a specific kind of entity in the kind or kinds of contexts that it is made for.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: A realizable entity, which is a necessary function of the bearer, and it is realized as an end-directed activity (a process in which the bearer is a participant).
code: NPO_316
comment: [source]: (1) BFO.owl 1.1; (2) Robert Arp and Barry Smith "Function, Role and Disposition in Basic Formal Ontology" NATURE PROCEEDINGS, 2008.
comment: a function "f" is a realizable dependent continuant; it has a bearer which is an independent continuant; instances of Function F have realizations; each realization is a) a process in which the bearer is participant; b) that It occurs in virtue of the bearer's physical make-up or structure. c) and this physical make-up is something which the bearer possesses because of how it came into being.
preferred name: function
DB xref ID: snap:Function

generically_dependent_continuant
type: Class
subclass of: dependent_continuant
disjoint with: specifically_dependent_continuant
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A continuant [snap:Continuant] that is dependent on one or other independent continuant [snap:IndependentContinuant] bearers. For every instance of A requires some instance of (an independent continuant [snap:IndependentContinuant] type) B but which instance of B serves can change from time to time. Examples: a certain PDF file that exists in different and in several hard drives</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>generically dependent continuant</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: Examples: a certain PDF file that exists in different and in several hard drives
code: NPO_1600
preferred name: generically dependent continuant
DB xref ID: snap:GenericallyDependentContinuant

independent_continuant
type: Class
subclass of: continuant
disjoint with: spatial_region
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A continuant [snap:Continuant] that is a bearer of quality [snap:Quality] and realizable entity [snap:RealizableEntity] entities, in which other entities inhere and which itself cannot inhere in anything.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>independent continuant</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_118
preferred name: independent continuant
DB xref ID: snap:IndependentContinuant
synonym: substantial entity

one_dimensional_region
type: Class
subclass of: spatial_region
disjoint with: three_dimensional_region
disjoint with: two_dimensional_region
disjoint with: zero_dimensional_region
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatial region [snap:SpatialRegion] with one dimension.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>one_dimensional_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1665
preferred name: one_dimensional_region
DB xref ID: snap:OneDimensionalRegion

quality
type: Class
subclass of: specifically_dependent_continuant
subclass of: Restriction
  on property: quality of
  some values from: independent_continuant
disjoint with: realizable_entity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A specifically dependent continuant [snap:SpecificallyDependentContinuant] that is exhibited if it inheres in an entity or entities at all (a categorical property).</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: Example: compound x is related to organic compound through the relation "presence of carbon"; here, the quality that inheres in compound x is organic)
comment: Examples: the color of a tomato, the ambient temperature of air, the circumference of a waist, the shape of a nose, the mass of a piece of gold, the weight of a chimpanzee
code: NPO_445
preferred name: quality
DB xref ID: snap:Quality

realizable_entity
type: Class
subclass of: specifically_dependent_continuant
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A specifically dependent continuant [snap:SpecificallyDependentContinuant] that inheres in continuant [snap:Continuant] entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>realizable entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_237
comment: Source: (1) BFO.owl v. 1.1; (2) Robert Arp and Barry Smith "Function, Role and Disposition in Basic Formal Ontology" NATURE PROCEEDINGS, 2008.
comment: realizable entities are defined by the fact that they can be realized (manifested, actualized, executed) in occurrents of corresponding sorts.
preferred name: realizable entity
DB xref ID: snap:RealizableEntity

role
type: Class
subclass of: realizable_entity
definition: <ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity [snap:RealizableEntity] the manifestation of which brings about some result or end that is not essential to a continuant [snap:Continuant] in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant [snap:Continuant] in some kinds of natural, social or institutional contexts.</ncicp:def-definition></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: At the instance-level, a role y is filled by x which is an instance of an independent continuant( x which takes the role of y: x is the filler, y is the role). A role y has a context P (e.g. an occurrent in which x is a participant). Every role term has its own qualities and behavior, given the context.
code: NPO_517
preferred name: role
comment: role is a realizable_entity whose manifestation brings about some result or end that is not typical of its bearer in virtue of the latter's physical structure. Rather role is played by an instance of the corresponding kind of continuant entity because this entity is in some special natural, social or institutional set of circumstances. (Source: Robert Arp and Barry Smith "Function, Role and Disposition in Basic Formal Ontology" NATURE PROCEEDINGS, 2008.)
DB xref ID: snap:Role

spatial_region
type: Class
subclass of: continuant
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A continuant [snap:Continuant] that is neither bearer of quality [snap:Quality] entities nor inheres in any other entities.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>spatial_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1664
DB xref ID: snap:SpatialRegion
preferred name: spatial_region

specifically_dependent_continuant
type: Class
subclass of: dependent_continuant
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A continuant [snap:Continuant] that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>specifically dependent continuant</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1601
comment: Synonyms: property, trope, mode; Examples: the mass of a cloud, the smell of mozzarella, the liquidity of blood, the color of a tomato, the disposition of fish to decay, the role of being a doctor, the function of the heart in the body: to pump blood, to receive de-oxygenated and oxygenated blood, etc.
DB xref ID: snap:SpecificallyDependentContinuant
preferred name: specifically dependent continuant

three_dimensional_region
type: Class
subclass of: spatial_region
disjoint with: two_dimensional_region
disjoint with: zero_dimensional_region
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatial region [snap:SpatialRegion] with three dimensions.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>three_dimensional_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
design note: Examples: a cube-shaped part of space, a sphere-shaped part of space.
code: NPO_1667
DB xref ID: snap:ThreeDimensionalRegion
preferred name: three_dimensional_region

two_dimensional_region
type: Class
subclass of: spatial_region
disjoint with: zero_dimensional_region
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatial region [snap:SpatialRegion] with two dimensions.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>two_dimensional_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1666
DB xref ID: snap:TwoDimensionalRegion
preferred name: two_dimensional_region

zero_dimensional_region
type: Class
subclass of: spatial_region
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatial region [snap:SpatialRegion] with no dimensions.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>zero_dimensional_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
design note: Example: A point.
code: NPO_1668
DB xref ID: snap:ZeroDimensionalRegion
preferred name: zero_dimensional_region

connected_spatiotemporal_region
type: Class
subclass of: spatiotemporal_region
disjoint with: scattered_spatiotemporal_region
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatiotemporal region [span:SpatiotemporalRegion] that has temporal and spatial dimensions such that all points within the spatiotemporal region are mediately or immediately connected to all other points within the same spatiotemporal region [span:SpatiotemporalRegion].</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>connected_spatiotemporal_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1671
preferred name: connected_spatiotemporal_region
DB xref ID: span:ConnectedSpatiotemporalRegion

connected_temporal_region
type: Class
subclass of: temporal_region
disjoint with: scattered_temporal_region
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A temporal region [span:TemporalRegion] every point of which is mediately or immediately connected with every other point of which.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>connected_temporal_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
design note: Examples: the 1970s years, the time from the beginning to the end of a heart attack, the time taken by cellular meiosis.
code: NPO_1676
preferred name: connected_temporal_region
DB xref ID: span:ConnectedTemporalRegion

fiat_process_part
type: Class
subclass of: processual_entity
disjoint with: process
disjoint with: process_aggregate
disjoint with: process_boundary
disjoint with: processual_context
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A processual entity [span:ProcessualEntity] that is part of a process but that does not have bona fide beginnings and endings corresponding to real discontinuities.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>fiat process part</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_417
comment: [source]: BFO v. 1.1
preferred name: fiat process part
comment: is it synonymous with "stage" which refers to temporally distinguised parts of an occurrent (eg., "infancy", "childhood", "adolescence", "adulthood" in the "life of a human being")?
DB xref ID: span:FiatProcessPart

occurrent
type: Class
subclass of: entity
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An entity [bfo:Entity] that has temporal parts and that happens, unfolds or develops through time. Sometimes also called perdurants.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>occurrent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
comment: Examples: the life of an organism, a surgical operation as processual context for a nosocomical infection, the spatiotemporal context occupied by a process of cellular meiosis, the most interesting part of Van Gogh's life, the spatiotemporal region occupied by the development of a cancer tumor
code: NPO_923
preferred name: occurrent
synonym: perdurant
DB xref ID: span:Occurrent

process
type: Class
subclass of: processual_entity
disjoint with: process_aggregate
disjoint with: process_boundary
disjoint with: processual_context
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A processual entity [span:ProcessualEntity] that is a maximally connected spatiotemporal whole and has bona fide beginnings and endings corresponding to real discontinuities.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_336
comment: [definition source]: BFO
preferred name: process
DB xref ID: span:Process

process_aggregate
type: Class
subclass of: processual_entity
disjoint with: process_boundary
disjoint with: processual_context
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A processual entity [span:ProcessualEntity] that is a mereological sum of process [span:Process] entities and possesses non-connected boundaries.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>process aggregate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_397
comment: [source]: BFO v. 1.1
preferred name: process aggregate
DB xref ID: span:ProcessAggregate

process_boundary
type: Class
subclass of: processual_entity
disjoint with: processual_context
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A processual entity [span:ProcessualEntity] that is the fiat or bona fide instantaneous temporal process boundary.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>process boundary</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_137
comment: [source]: BFO v. 1.1
preferred name: process boundary
DB xref ID: span:ProcessBoundary

processual_context
type: Class
subclass of: processual_entity
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An occurrent [span:Occurrent] consisting of a characteristic spatial shape inhering in some arrangement of other occurrent [span:Occurrent] entities. Processual context [span:ProcessualContext] entities are characteristically entities at or in which other occurrent [span:Occurrent] entities can be located or occur.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>processual_context</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
description: Examples: The processual context for a given manipulation occurring as part of an experiment is made of processual entities which occur in parallel, are not necessarily all parts of the experiment themselves and may involve continuant [snap:Continuant] entities which are in the spatial vicinity of the participants in the experiment. An instance of a processual context [span:ProcessualContext] is a mixture of processual entity [span:ProcessualEntity] which stand as surrounding environments for other processual entity [span:ProcessualEntity] entities. The class processual context [span:ProcessualContext] is the analogous among occurrent [span:Occurrent] entities to the class site [snap:Site] among continuant [snap:Continuant] entities.
code: NPO_1669
preferred name: processual_context
DB xref ID: span:ProcessualContext

processual_entity
type: Class
subclass of: occurrent
disjoint with: spatiotemporal_region
disjoint with: temporal_region
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An occurrent [span:Occurrent] that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm><ncicp:term-name>processual entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_703
comment: [source]: BFO v. 1.1
preferred name: processual entity
DB xref ID: span:ProcessualEntity

scattered_spatiotemporal_region
type: Class
subclass of: spatiotemporal_region
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatiotemporal region [span:Spatiotemporal Region] that has spatial and temporal dimensions and every spatial and temporal point of which is not connectedd with every other spatial and temporal point of which.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>scattered_spatiotemporal_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1672
preferred name: scattered_spatiotemporal_region
DB xref ID: span:ScatteredSpatiotemporalRegion

scattered_temporal_region
type: Class
subclass of: temporal_region
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A temporal region [span:TemporalRegion] every point of which is not mediately or immediately connected with every other point of which.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>scattered_temporal_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
design note: Examples: The time occupied by the indiviual games of the World Cup.
code: NPO_1677
preferred name: scattered_temporal_region
DB xref ID: span:ScatteredTemporalRegion

spatiotemporal_instant
type: Class
subclass of: connected_spatiotemporal_region
disjoint with: spatiotemporal_interval
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A connected spatiotemporal region [span:ConnectedSpatiotemporalRegion] at a specific moment.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>spatiotemporal_instant</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1673
DB xref ID: span:SpatiotemporalInstant
preferred name: spatiotemporal_instant

spatiotemporal_interval
type: Class
subclass of: connected_spatiotemporal_region
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A connected spatiotemporal region [span:ConnectedSpatiotemporalRegion] at a specific moment.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>spatiotemporal_interval</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1674
DB xref ID: span:SpatiotemporalInterval
preferred name: spatiotemporal_interval

spatiotemporal_region
type: Class
subclass of: occurrent
disjoint with: temporal_region
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An occurrent [span:Occurrent] at or in which processual entity [span:ProcessualEntity] entities can be located.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>spatiotemporal_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
code: NPO_1670
DB xref ID: span:SpatiotemporalRegion
preferred name: spatiotemporal_region

temporal_instant
type: Class
subclass of: connected_temporal_region
disjoint with: temporal_interval
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A connected temporal region [span:ConnectedTemporalRegion] comprising a single moment of time.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>temporal_instant</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
design note: Examples: right now, the moment at which a finger is detached in an industrial accident, the moment at which a child is born, the moment of death.
code: NPO_1678
DB xref ID: span:TemporalInstant
preferred name: temporal_instant

temporal_interval
type: Class
subclass of: connected_temporal_region
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A connected temporal region [span:ConnectedTemporalRegion] lasting for more than a single moment of time.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>temporal_interval</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
design note: Examples: any continuous temporal duration during which a process occurs.
code: NPO_1679
DB xref ID: span:TemporalInterval
preferred name: temporal_interval

temporal_region
type: Class
subclass of: occurrent
definition: <ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An occurrent [span:Occurrent] that is part of time.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
FULL SYN: <ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>temporal_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
design note: Examples: the time it takes to run a marathon, the duration of a surgical procedure, the moment of death.
code: NPO_1675
DB xref ID: span:TemporalRegion
preferred name: temporal_region

Restriction
on property: atomic Number
has value: 13

Restriction
on property: atomic Number
has value: 25

Restriction
on property: atomic Number
has value: 57

Restriction
on property: atomic Number
has value: 87

Restriction
on property: atomic Number
has value: 55

Restriction
on property: atomic Number
has value: 28

Restriction
on property: atomic Number
has value: 41

Restriction
on property: atomic Number
has value: 10

Restriction
on property: atomic Number
has value: 80

Restriction
on property: atomic Number
has value: 30

Restriction
on property: atomic Number
has value: 19

Restriction
on property: atomic Number
has value: 93

Restriction
on property: atomic Number
has value: 105

Restriction
on property: atomic Number
has value: 88

Restriction
on property: atomic Number
has value: 76

Restriction
on property: atomic Number
has value: 101

Restriction
on property: atomic Number
has value: 59

Restriction
on property: atomic Number
has value: 38

Restriction
on property: atomic Number
has value: 45

Restriction
on property: atomic Number
has value: 44

Restriction
on property: atomic Number
has value: 103

Restriction
on property: atomic Number
has value: 39

Restriction
on property: atomic Number
has value: 1

Restriction
on property: atomic Number
has value: 2

Restriction
on property: atomic Number
has value: 36