The NPO was primarily developed by Dennis G. Thomas in collaboration with Nathan A. Baker and Rohit V. Pappu. This development was supported by the NIH through grants U54 CA119342 and U54 HG004028.
NanoParticle Ontology (NPO): An ontology for representing the knowledge underlying the description and characterization of nanoparticles.
Relation between a continuant and an occurrent in which the continuant participates in and causes the occurrence of that occurrent.
This relation is taken from the Ontology for Biomedical Investigations (OBI: Version 2009-11-06 Philly (aka version 1.0) Release Candidate)
A relation that indicates the process, property, or substance analyzed in an assay.
A relation between an entity and a dependent continuant.
(source): OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005)
A relation between a material continuant and an immaterial continuant, when the material continuant at any given time is located in but shares no parts in common with the immaterial continuant at the same time.
C contained_in C1; Cs are material continuants, C1s are immaterial continuants (holes, cavities): Every C at any given time is located in but shares no parts in common with C1 at the same time.
A reciprocal relation of contained_in, where given an immaterial continuant at some time, there is a material continuant contained in the immaterial continuant at the same time.
C contains C1; Cs are immaterial continuants, C1s are material continuants: for all C, t, , if c is an instance of C at time t, then there is some c1 such that c1 is an instance of C1 and c1 contained_in c at t.
A relation which indicates the symbol that denotes something.
A relation between distinct material continuants when one succeeds the other across a temporal divide in such a way that at least a significant portion of the matter of the earlier continuant is inherited by the later.
The temporal relation of derivation is more complex. Transformation, on the instance level, is just the relation of identity: each adult is identical to some child existing at some earlier time. Derivation on the instance-level is a relation holding between non-identicals. More precisely, it holds between distinct material continuants when one succeeds the other across a temporal divide in such a way that at least a biologically significant portion of the matter of the earlier continuant is inherited by the later. Thus we will have axioms to the effect that from c derives_from c1 we can infer that c and c1 are not identical and that there is some instant of time t such that c1 exists only prior to and c only subsequent to t. We will also be able to infer that the spatial region occupied by c as it begins to exist at t overlaps with the spatial region occupied by c1 as it ceases to exist in the same instant.
[source]:OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005)
A relation which indicates the property determined by a characterization.
A relationship that indicates the bearer inhering a function.
A relation which is between a process, a continuant and a time whenever the continuant is a participant in the process and is at the same time directly causally responsible for its occurrence.
Only material continuants can fill the agent role, that if c fills the agent role at t, then c must have existed at times earlier than t, that it must exercise its agent role for an interval of time including t, and so on.
P has_agent C; Ps are processes, Cs are material continuants. Every P involves some C as agent (the C is involved in and is causally responsible for the P)
A relation which indicates the application or use of an entity.
A relationship to indicate that one atom has a covalent bond with another atom.
A relation used between material continuants where one is composed of the other. In the NPO, this relation is used mostly for representing the composition of nanoparticle formulations or nanoparticles.
C has_component_part C1, means that every instance c of C is prepared from some instances c1 of C1 and a significant material portion of c1 becomes part of the constituting material of c when c begins to exist.
A has_component_part type of relation, which is used to infer that a particular component in a nanoparticle formulation is attached or chemically conjugated to some other chemical components of the same nanoparticle formulation by a method of attachment.
A relation which indicates the value of a property that can be quantified.
A relationship to indicate that one atom has a double covalent bond with another atom.
A has_component_part type of relation, which is used to infer that a particular component (molecular structure or nanostructure) becomes encapsulated - due to non-covalent interactions - in a nanoparticle by a method of encapsulation.
A relation that indicates the endpoint measured with an assay.
A has_component_part type of relation, which is used to infer that a particular component (molecular structure or nanostructure) is entrapped - due to non-covalent interactions - in a nanoparticle by a method of entrapment.
A relationship that indicates the function inhering in an entity.
A relation which indicates the name of the type of identification, as well as other attributes of an entity.
A relationship between a continuant and an occurrent that has other participating continuants, which holds if at every time t an instance of the occurrent is created, there is at least one instance of the continuant participating in it at time t1 > t, and it is formed / derived from the instances of those continuants that participate at time t.
If C and C1 are continuant classes, then C has_part C1 means that every instance of C at any time has part some instances of C1 at the same time. [formal definition]: C has_part C1 holds true if and only if every continuant c that instantiates C at some time t, there is some continuant c1 that instantiates C1 at t such that c1 is part of c at t. Examples: fluorescein isothiocyanate has_part isothiocyanate group gold quantum dot has_part gold core-shell nanoparticle has_part core core-shell nanoparticle has_part shell
If P and P1 are occurrent classes, then P has_part P1 means that every instance of P has part some instances of P1. [formal definition]:P has_part P1 if and only if every occurrent p that instantiates P there is some occurrent p1 that instantiates P1 such that p1 is part of p. Examples: covalent linkage has_part covalent interaction visualization of cellular uptake of nanoparticles has_part imaging of nanoparticles
Transitive parthood relation in which one entity has itself, or another entity as a part, and the relation is valid for use only between continuants or between occurrents but not between a continuant and an occurrent.
A relationship between a continuant and an occurrent, which holds if at every time an instance of the occurrent is created, it has at least one instance of the continuant participating in it at the same time.
Examples: nanoparticle-mediated drug delivery has_participant drug-loaded nanoparticle
If P is an occurrent class and C a continuant class, then P has_participant C means that every instance of P involves some instances of C as participants. [formal definition]: P has_participant C hold true, if and only if every occurrent p that instantiates P there is some continuant c, and some time t, such that c instantiates C at t and p has participant c at t.
A relation between an entity and a specifically dependent continuant.
A relation which indicates the quality inhering in an entity. It is a general relation between any class and subclasses of Quality.
A relationship to indicate that a class is related to another class.
If C is an independent continuant and C1 a role continuant class, then C has_role R1 means that every instance of C fills some instances of role C1 everytime the role is realized in a particular context.
Relation between an independent continuant and a role.
[source]: OBO Relation Ontology (release version 0.99, date 07:14:2006)
e.g., X (molecular entity) has_role Y (role), i.e, X fills the role of Y
A relationship to indicate that one atom has a single covalent bond with another atom.
A relation that indicates the temperature at which a process is performed.
A relation that indicates the duration for a process to occur.
A relationship to indicate that one atom has a triple covalent bond with another atom.
A relation which indicates the unit of a measured quantity.
A relation between a dependent continuant D and an entity E. D inheres_in E if: given any d that instantiates D at t, there exists some e that instantiates E at t and d *inheres_in* e at t. Here *inheres_in* is the primitive instance level relation. [source: OBI]
A relation that indicates the process or phenomenon signified by a measured endpoint of an assay.
A parthood relation that holds when C is part of C and C1 has part C, where C and C1 are continuant classes.
[source]: OBO Relation Ontology (release version 0.99); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005)
e.g.,carbon atom is_integral_part_of carbon (carbon is_a element)
A relationship between a realizable entity and an occurrent.
A relation which indicates a qualitative or quantitative measure (estimate) of an entity based on measurement, calculation, or counting.
A relation between two occurrents where one negatively regulates the other.
A relation which indicates the type of process that determines the value of a parameter.
If C and C1 are continuant classes, then C part_of C1 means that every instance of C (c) at any time is part of some instances of C1 (c1) at the same time []. Note that whenever we read "some instances" it should be understood as reading "one or more instances". [formal definition]: C part_of C1 holds true if and only if every continuant c that instantiates C at some time t, there is some continuant c1 that instantiates C1 at t such that c is part of c1 at t. Examples: carboxyl group part_of carboxylic acid dendrimer generation layer part_of dendrimer hydrophobic core of lipid bilayer part_of lipid bilayer hollow core of nanocage part_of nanocage
If P and P1 are occurrent classes, then P part_of P1 means that every instance of P is part of some instances of P1. [formal definition]: P part_of P1 holds true if and only if every occurrent p that instantiates P there is some process p1 that instantiates P1 such that p is part of p1. Examples: drug release from nanoparticle during systemic circulation part_of systemic circulation of drug-loaded nanoparticle
Transitive parthood relation in which one entity is part of another entity, and the relation is valid for use between continuants or between occurrents but not between a continuant and an occurrent.
[source]: OBO Relation Ontology (release version 0.99, date 07:14:2006); Barry Smith et al, Relations in biomedical ontologies, Genome Biology (2005)
A relationship between a continuant and an occurrent, which holds iff at every time an instance of the continuant is created, it participates in at least one instance of the occurrent at the same time.
Example: catalyst participates_in catalytic reaction fluorometer participates_in measurement of fluorescence intensity
If C is a continuant class and P an occurrent class, then C participates_in P means that every instance of C participates in some instances of P. [formal definition]: C participates_in P if and only if every continuant c that instantiates C there is some occurrent p, and some time t, such that p instantiates P and c participates in p at t.
A relation between two occurrents where one positively regulates the other.
A relation which indicates the type of process that determines a qualitative or quantitative measure of the property.
A relation which indicates the entity which bears a property.
A relation between a quality and its bearer.
A relation between an occurrent to a realizable entity.
A relationship between two occurrents where one regulates the other.
A relationship indicating the bearer inhering a role.
A relationship that indicates the response caused by a stimulus. (e.g., the response caused by the action of a stimulus on a nanoparticle)
A relationship which indicates the principle based on which a technique is used.
A relation which indicates the process for which the technique is used.
A relation that indicates the quantity associated with a unit of measure. It is an inverse relation of "has unit of measure".
A relation which indicates that the type of instrument used in a process.
A relation which indicates the reagent used in an assay.
A relation which indicates the technique used for accomplishing a purpose.
This relation is used to indicate other datum values that have to be specified/recorded when a particular datum value is recorded.
This property is in support of the NCI Edit Tab.
It begins with the prefix "NPO_" followed by a number (e.g., NPO_250). The smallest code value is NPO_100 of class Cylinder.
The property code is used to indicate a unique identification code for every class in the NPO.
The property dBXrefID is used to indicate the reference ID of a class from an external CV / ontology / database.
The property definition is used to indicate the meaning or definition of a class or a class-level association in the NPO.
The property preferred name is used to indicate the preferred name of a class or a class-level association in the NPO.
The property symbol is used to enter a symbol that denotes the name of an entity.
The property synonym is used to indicate an alternate name of a class or a class-level association in the NPO.
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shape formed by the surface of a 3-dimensional object, where points on the surface are at a fixed distance from a given straight line (axis of the cylinder).</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cylindrical shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nucleic acid composed of nucleotides containing deoxyribose sugar and linked by phosphodiester bonds. DNA contains the genetic information of organisms.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>deoxyribonucleic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A non-metal which is any of the following elements: astatine, bromine, chlorine, fluorine, iodine.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>A nanomaterial which has one, two, or three external dimensions in the nanoscale size range.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
This term had the preferred name "nanostructure" in version 2010-10-31.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a molecular entity because it consists of one or more atoms of the same element.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spheroidal shape, which is generated by half-revolution of an ellipse around its major axis.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>prolate spheroidal shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a molecular entity because it consists of more than one atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a molecular entity because it consists of only one atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a molecular entity because it consists of two or more chemical elements.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 13.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>aluminium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is loaded with methotrexate.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>methotrexate-loaded nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 16 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Group 16 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The aqueous space enclosed by lipid bilayer of a liposome.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hydrophilic core of liposome</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 38.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 107.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>bohrium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a coating agent composed of a lipid.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>lipid-coated nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carboxylate is an organic compound which is characterized by the presence of a carboxylate group. It has the structure R-C(=O)-[O-], where 'R' denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 87.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of carbon.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carbon molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanotube which consists of multiple layers or sheets of hexagonal arrays of an element or molecule, rolled in on themselves to form concentric seamless cylinders with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>multi-walled nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acyl halide group in which the halogen atom is a chlorine atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>acyl chloride group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrophobic property by virtue of which the molecule is able to combine with or dissolve in lipids or fats.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>An engineered nanomaterial which has an end-directed activity/function.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative measure of polydispersity. It is a measure of the distribution of molecular mass in a given polymer sample or the distribution of particle sizes in a particulate sample. In polymeric samples, the polydispersity index is calculated as the weight average molecular weight divided by the number average molecular weight.</ncicp:def-definition><ncicp:Definition_Review_Date>100727</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>polydispersity index</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dimensionless unit which denotes the ratio of weights.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>weight ratio</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quantitative measure of magnetism, which is a measure of the strength of a magnetic field over a given area.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>magnetic flux</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of measurement for magnetic flux.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>magnetic flux unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The amount of magnetic flux in a unit area perpendicular to the direction of magnetic flow.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>magnetic flux density</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of measurement for magnetic flux density.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>magnetic flux density unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a substance by virtue of the amount of it there is mixed with another substance.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which is derived by the removal of one chlorine atom from chlorosulfuric acid, and has the structure -S(=O)(=O)-Cl. The group is characteristic of sulfonyl chloride derivatives.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>sulfonyl chloride group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The sum of the relative atomic masses of the constituent atoms of a molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>molecular weight</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A force of interaction between atoms, ions, molecules or groups.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>chemical interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The number of moles of a solute dissolved in a liter of solution.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The number of moles of solute dissolved in one kilogram of solvent.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Concentration of a solution expressed in gram equivalents of solute per liter.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Concentration, which is the amount of cells in a medium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cell concentration</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of toxicity which is the concentration of a drug or inhibitor that is required to inhibit a biological process or a participant's activity in that process by half. The realization of this realizable entity is the 50% inhibition of a biological process or the activity (molecular function) of a biological occurring chemical entity (e.g., gene, gene product)</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of toxicity which is the concentration of a chemical or biologic preparation that is likely to cause death in 50% of animals or cells being tested. The realization of this realizable entity is the death of 50% of animals or cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>pH of value between 7 and 14.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>basic pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aminoacid which is polar in nature.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>polar aminoacid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>pH of value between 0 and 7.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>acidic pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>pH of value equal to 7.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>neutral pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A qualitative measure of acidity in the basic pH range.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A qualitative measure of acidity in the acidic pH range.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The pH at which a particular molecule or surface carries no net electrical charge.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>isoelectric point</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of cell concentration which is equal to one cell in a volume of 1 microliter.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cells per microliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 2 (IUPAC style) of the periodic table: beryllium (Be), magnesium (Mg), calcium (Ca), strontium (Sr), barium (Ba) and radium (Ra).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>alkali earth metal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality which denotes the amount of substance (matter).</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>amount of substance</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Weight inhering in the body of an animal species.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>body weight</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A two-dimensional nanoparticle which is shaped like a long dowel and has diameter measured in the nanoscale.</ncicp:def-definition></ncicp:ComplexDefinition>
[NCI_Thesaurus definition]: Nanoscale structures that are shaped like long dowels. The structures have a diameter that is measured in the nanoscale with an extended length parameter.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Weight inhering in a tumor.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tumor weight</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Area of an object's surface.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>surface area</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antimetastic agent, which prevents metastasis by interfering with the aggregation of tumor cells.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>anti-adhesion agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An inner transition element which is any element in the series of 15 radioactive metallic elements with atomic numbers 89 (actinium) to 103 (lawrencium).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An area unit which is equal to 10^[-18] m^[2].</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>square nanometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A two-dimensional nanoparticle which consists of one or more sheets of hexagonal arrays of an element or molecule, rolled into seamless cylinders with capped ends.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in micrograms divided by the volume in milliliters.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>microgram per milliliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in micrograms divided by the volume in microliters.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>microgram per microliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Role of a surface modifying agent that is attached to the surface of a nanoparticle in a nanoparticle formulation.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nanoparticle surface modifying role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iodoacetyl group is an organic group which has the structure -C(=O)-CH2-I. The group is characteristic of an iodoacetyl molecule in which it is attached either to a hydrogen atom or a carbon atom via single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>iodoacetyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a continuant bearer by virtue of its relation to time during its existence.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>time quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A time quality inhering in a bearer by virtue of how long it has existed.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 17.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A property of matter responsible for electrical phenomena.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>electric charge</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a measure of the quantity of charge.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>electric charge unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anticancer drug that acts like estrogen on some tissues but blocks the effect of estrogen on other tissues.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>selective estrogen receptor modulator</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The potential difference between the bulk dispersion medium (liquid) and the stationary layer of liquid near the surface of the dispersed particulate.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>zeta potential</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric charge unit which which is approximately equal to 3.33564 × 10^[?10] C.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of electric charge where one ampere-hour is equal to 3600 coulombs.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>ampere hour</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric charge quality which signifies a deficiency of electrons in the bearer.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>positive charge</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric charge quality which signifies a surplus of electrons in the bearer.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>negative charge</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric charge quality which signifies zero net charge in the bearer.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>neutral charge</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity which inheres in a continuant or a group of continuants under certain conditions, and it is realized through the occurrence of a process, activity or interaction per unit time.</ncicp:def-definition><ncicp:Definition_Review_Date>100429</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The rate of suppression in tumor growth.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tumor suppression rate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element in the first row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Period 1 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The rate of change or movement in the mass (amount of matter) of a physical object.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>mass rate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A measure of the change or movement of mass per unit time.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>mass rate unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of mass rate expressed as kilograms per day.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>kilogram per day</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Mobility of a charged particle in electrophoresis, measured as the rate of migration (usually in cm/s) per unit electric field strength (usually V/cm) of the charged particle.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>electrophoretic mobility</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of measure of electrophoretic mobility.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>unit of electrophoretic mobility</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of electrophoretic mobility of a charged particle moving with a velocity of 1cm/s in an electric field of strength equal to 1 volt/s.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>square centimeter per volt per second</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A sulfonyl chloride derivative is an organic compound which is characterized by the presence of a sulfonyl chloride group. It has the structure R-S(=O)(=O)-Cl, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>sulfonyl chloride derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A percentage unit of molar concentration which is equal to 100 times the mole fraction (number of moles of solute in proportion to the total number of moles in a solution.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>mole percentage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 106.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity inhering in a bearer by virtue of ratio of the bearer's output to the bearer's input.</ncicp:def-definition><ncicp:Definition_Review_Date>100429</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a material entity by virtue of it having the capacity to carry an amount of another material entity.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>loading efficiency</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The efficiency inhering in a bearer's ability to facilitate transfection.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>transfection efficiency</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The efficiency inhering in a nanomaterial or supramolecular structure by virtue of its capacity to encapsulate an amount of molecular entity, isotope or nanomaterial.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>encapsulation efficiency</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 3-D extent quality of the amount of 3-dimensional space a tumor occupies.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tumor volume</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity inhering in a bearer which causes harm to the growth and functioning of cells, tissues, organs and the body.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Toxicity that impairs or damages the immune system.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Toxicity that impairs or damages cells, and it is a desired property for the killing of growing tumor cells.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Toxicity that inheres in a drug which causes adverse effects, when the drug is used therapeutically or diagnostically.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>drug toxicity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Viability of a cell to proliferate, grow, divide, or repair damaged cell components.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cell viability</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in an object by virtue of the type, quantities or relative ratios of chemical components of the inhering entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100701</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO:0000025 (composition)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>chemical composition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A composition quality which is the degree to which an object bearer is free of contaminants or heterogeneous components.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>The maximum magnitude (value without regard to sign) of the disturbance of a sound wave.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>amplitude of sound wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An experiment performed to determine the distinctive characteristics (property / behavior) or essential features of a material entity.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of characterization, which is performed to determine the physicochemical (material and structural) properties of an object.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>physicochemical characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of characterization, which is performed to determine a property/quality that indicates the behavior of a material entity in vitro.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>in vitro characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of characterization, which is performed to determine a property/quality that indicates the behavior of a material entity in vivo.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>in vivo characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of physical characterization, which is performed to determine the molecular weight of a molecular entity.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>molecular weight characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic agent that kills cancer cells by interfering with mitosis.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>antimitotic agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of physical characterization, which is performed to determine the purity of a chemical substance.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>purity characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of physical characterization, which is performed to determine the shape of an object.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>shape characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of physical characterization, which is performed to determine the size of an object.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>size characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of physical characterization, which is performed to determine the surface property of an object.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>surface characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A property inhering in the surface of an object.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>surface property</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dimensionless unit which denotes the ratio of longest and shortest dimensions of an object.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>aspect ratio</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A measure of diameter obtained by dividing a sum of several diameter values by the total number of values.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>average diameter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fiat material part which is a thin outer layer or film of material covering the surface of an object (e.g., a nanoparticle).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has magnetic property.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>magnetic nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of silicon dioxide.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>silica nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
superparamagnetic iron oxide nanoparticle
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iron oxide nanoparticle which has superparamagnetic property.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>superparamagnetic iron oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of polymer.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>polymeric nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition inhering in a bearer which emits light of longer wavelength during absorption of radiation of shorter (invisible) wavelength.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has fluorescence property.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>fluorescent nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which exists while dispersed in a hydrogel.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hydrogel nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The surface of a nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>surface of nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A linkage in which a molecular entity or nanostructure becomes enclosed due to non-covalent interactions, in a nanoparticle's material site that is fully bounded by the particle's constituting material.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An isotope which releases radiation as it breaks down.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Emission of particles or electromagnetic radiation caused by the spontaneous disintegration of atoms of unstable nuclei in order to form atoms with stable nuclei.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition inhering in the bearer by virtue of it exhibiting or causing radioactivity.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of a metal.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>metal nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antibody which has molecular mass of 150-950 kDa, and consists of one or more basic units of four polypeptide chains comprising of two heavy chains and two light chains held together by disulphide links.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An immunoglobulin isotype which is associated with antibody-mediated mucosal immunity. It is secreted as dimers into the mucosa and is the most effective isotype at fixing complement by the alternative pathway, even though it lacks the ability to fix complement by the classical pathway. There are two subtypes in the human - IgA1 and IgA2. [Source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>immunoglobulin A</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An immunoglobulin isotype, which is expressed on naive B cells along with IgM.[Source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>immunoglobulin D</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An immunoglobulin isotype, which has the unique ability to bind with high affinity to IgE receptors (FceRI) on mast cells and basophils and induce degranulation and cytokine production by these cells when they are crosslinked by antigen. In addition to a central role in atopy and allergic responses, it has been speculated that IgE-mediated mast cell degranulation, by its release of mediators that increase vascular permeability, has an important role in the initiation of immune response in general. [Source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>immunoglobulin E</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An immunoglobulin isotype, which characterizes secondary immune responses. This isotype is further broken down into several smaller subclasses (IgG1, IgG2a, IgG2b, IgG3 in the mouse; IgG1-4 in the human), and each subclass is differentially synthesized and secreted into the serum upon differential immune stimuli.[Source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>immunoglobulin G</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A main immunoglobulin isotype which is secreted during a primary immune response. IgM binds with low affinity but high avidity (multiple binding sites) because it not only occurs as monomers but also as pentamers and hexamers.[Source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>immunoglobulin M</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A class of immunoglobulins, which refers to genetic variations or differences in the constant region of the heavy chain of the Ig</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>immunoglobulin isotype</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A function which inheres in a material entity, and is realized in a process in which the material entity is used to target another material entity.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>targeting function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A function inhering in a material entity by virtue of its use for imaging purposes.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>imaging function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A function inhering in a material entity by virtue of its use for therapeutic purposes.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>therapeutic function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acyl halide compound is an acyl compound which is characterized by the presence of acyl halide group. It has the structure R-(C=O)-X, where 'R' denotes an organic group and X denotes a halogen atom (F, Cl, Br or I).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>acyl halide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Chemiluminescence produced by living systems.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A small representative portion of a nanoparticle formulation.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nanoparticle sample</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A systematic procedure or a practical method which is used for accomplishing a task.</ncicp:def-definition></ncicp:ComplexDefinition>
[DGT, June 10, 2010]: Description for a specific type of technique could contain the following types of information: 1) principle used in the technique (e.g. NMR for NMR spectroscopy), 2) description of the principle if the term that describes the principle is not represented in the ontology, 3) tool used in a technique (e.g., scanning electron microscope in scanning electron microscopy), 4) applications of the technique, and 5) information on how to use the technique for each type of application.
<ncicp:ComplexDefinition><ncicp:def-definition>A temporal interval which is the time during which a process continues to occur.</ncicp:def-definition><ncicp:Definition_Review_Date>130524</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A scientific procedure which is a process of conducting a test under controlled conditions to make a discovery, test a hypothesis, or demonstrate a known fact.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An experiment which is used to 1) analyze or measure (qualitatively/quantitatively) the composition and property of a substance; or, 2) to analyze a process or activity.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A bioassay conducted in an artificial environment (e.g., test tube) outside the body of a living organism, under controlled conditions.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>in vitro assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -S-. The group is characteristic of thioether wherein the sulfur atom is attached to two carbon atoms via single covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>thioether group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A bioassay conducted inside the body of a living organism.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>in vivo assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An assay which is used to test or analyse the biological activity of a substance, and which is performed by studying its effect on an organism or in a test tube under controlled conditions.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An assay for evaluating the physical properties of a sample.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>physical assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Characterization of nanoparticles or nanoparticle formulations.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nanoparticle characterization</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule used for stabilizing an emulsion.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A technique which uses a microscope to study a material object or a process that cannot be seen by the naked eye.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A technique which is used to separate substances from mixtures.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>separation technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A separation technique which uses a centrifuge to generate a centrifugal force for separating fluids of different densities from mixtures or for separating liquids from solids.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A separation technique used for separating charged particles in a fluid or gel under the action of an electric field. The electric field causes the movement of charged particles.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Electrophoresis method used for separating molecules of proteins and nucleic acids from a sample mixture of similar molecules through a gelatinous matrix. Subject to an electric field, each molecule in the sample mixture migrates through the matrix at a different rate, depending mainly on electrical charge and size, resulting in spatial separation within the matrix of each molecular species in the sample mixture. Agarose and acrylamide in a cylindrical tube or slab gel are commonly used media for electrophoresis of proteins and nucleic acids.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gel electrophoresis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Gel electrophoresis in which highly purified agar is used as the diffusion medium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>agarose gel electrophoresis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Gel electrophoresis technique in which a polyacrylamide gel is used as the diffusion medium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>polyacrylamide gel electrophoresis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process of examining the component parts of a whole and their relations in making up the whole [source: WordNet]. e.g., the identification and measurement of chemical constituents of a substance or specimen.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Analysis of protein components in a sample.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>protein analysis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A technique which is used for the detection or identification of proteins or peptides that have been separated by gel electrophoresis and transferred onto nitrocellulose or other type of paper or nylon membrane. The proteins are then detected by reaction with enzymatically labeled or radiolabeled antibody probes.</ncicp:def-definition><ncicp:Definition_Review_Date>100614</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>western blot analysis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process or action of identifying the presence of something.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Detection of proteins or a protein components in a sample.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>detection of proteins</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polyacrylamide gel electrophoresis technique for separating proteins in a sample which is prepared with sodium dodecyl sulfate (SDS) as a buffer that maintains the proteins in their denatured states.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>SDS polyacrylamide gel electrophoresis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
sodium dodecyl sulfate - polyacrylamide gel electrophoresis
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A microscopy technique based on the use of electron microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>electron microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electron microscopy technique based on the use of scanning electron microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>scanning electron microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electron microscopy technique based on the use of transmission electron microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>transmission electron microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
A light source at the top of the TEM emits the electrons that travel through vacuum in the column of the microscope. Instead of glass lenses focusing the light in the light microscope, the TEM uses electromagnetic lenses to focus the electrons into a very thin beam. The electron beam then travels through the specimen you want to study. Depending on the density of the material present, some of the electrons are scattered and disappear from the beam. At the bottom of the microscope the unscattered electrons hit a fluorescent screen, which gives rise to a shadow image of the specimen with its different parts displayed in varied darkness according to their density. The image can be studied directly by the operator or photographed with a camera. [source: http://Nobelprize.org]
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A microscopy technique based on the use of optical microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>optical microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An optical microscopy technique based on the use of fluorescence microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>fluorescence microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A microscopy technique based on the use of scanning probe microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>scanning probe microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A scanning probe microscopy technique based on the use of atomic force microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>atomic force microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A scanning probe microscopy technique based on the use of scanning tunneling microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>scanning tunneling microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A device or tool that requires skill for proper use, and it is intended for a purpose.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An instrument which is used for magnifying and viewing images of objects that are too small to be seen by the naked or unaided eye. [source:http://encyclopedia.thefreedictionary.com/microscope]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A microscope that is similar in purpose to a light microscope but achieves much greater resolving power by using a parallel beam of electrons to illuminate the object instead of a beam of light. [source:WordNet 3.0]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>electron microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
Electron Microscopes(EMs) function exactly as their optical counterparts except that they use a focused beam of electrons instead of light to "image" the specimen and gain information as to its structure and composition. The basic steps involved in all EMs: 1. A stream of electrons is formed (by the Electron Source) and accelerated toward the specimen using a positive electrical potential 2. This stream is confined and focused using metal apertures and magnetic lenses into a thin, focused, monochromatic beam. 3. This beam is focused onto the sample using a magnetic lens 4. Interactions occur inside the irradiated sample, affecting the electron beam These interactions and effects are detected and transformed into an image The above steps are carried out in all EMs regardless of type. [source: http://unl.edu/CMRAcfem/em.htm]
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A microscope which uses visible light and a system of lenses to magnify images of small objects.[source: http://encyclopedia.thefreedictionary.com]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>optical microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 53.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>iodine atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electron microscope which scans the surface of a sample with a beam of electrons and detects the interaction of the electrons with the atoms on the surface to produce a topographical image of the sample.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>scanning electron microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electron microscope which transmits a beam of electrons through a finely sliced section of a specimen/sample and creates an image of the specimen/sample based on its effect on the phase of the electrons that pass through.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>transmission electron microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
TEMs use electrons as light source and their much lower wavelength makes it possible to get a resolution a thousand times better than with a light microscope.[source: http://Nobelprize.org]
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A microscope which forms images of surfaces using a physical probe that scans the specimen and records the probe-surface interaction as a function of position.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>scanning probe microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An optical microscope which is used to study the properties of a specimen or sample based on the phenomena of fluorescence and phosphorescence. The microscope has a filter which allows radiation of a specific wavelength of light to pass through.The specimen or the sample contains components labeled with a fluorescent molecule which absorbs this light, and then emits light of a longer wavelength. A second filter of the microscope separates the emitted light from the brighter excitation light (shorter wavelength). As a result, the fluorescing regions of the sample shine out against a dark background with high contrast, when observed through the microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>fluorescence microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
[definition: adapted from http://nobelprize.org; http://en.wikipedia.org/wiki/Fluorescence_microscope ]
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A scanning probe microscope which consists of a microscale cantilever with a sharp tip (probe) at its end that is used to scan the specimen surface. The probe is extremely close to - but does not touch-the surface. As the probe traverses the surface, attractive and repulsive forces arising between it and the atoms on the surface induce forces on the probe that bend the cantilever. The amount of bending is measured and recorded, providing a map of the atoms on the surface. Atomic force microscopes can achieve magnification of a factor of 5 × 10^6, with a resolution of 2 angstroms, sufficient to resolve individual carbon atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>atomic force microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
[definition: adapted from NCIT, http://www.thefreedictionary.com, http://en.wikipedia.org]
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A scanning probe microscope which consists of a probe with a small voltage applied to it ending in a tiny sharp electrically conducting tip (ideally consisting of one atom) that is moved close the material's surface. It scans the surface of a sample with a beam of electrons, causing a narrow channel of tunneling electrons to flow between the sample and the beam, and producing three-dimensional images of atomic topography and structure.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>scanning tunneling microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
[definition: adapted from http://www.thefreedictionary.com]
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A scanning probe microscope which is derived from atomic force microscope, having a magnetized tip that map the spatial distribution of magnetism by measuring the magnetic interactions between the sample and the tip. It is used to study magnetic materials.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>magnetic force microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
[definition: adapted from http://encyclopedia.thefreedictionary.com]
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is loaded with doxorubicin.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>doxorubicin-loaded nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
high resolution transmission electron microscopy
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A transmission electron microscopy technique based on the use of high resolution transmission electron microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>high resolution transmission electron microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
high resolution transmission electron microscope
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A transmission electron microscope which operates at an imaging mode that allows the imaging of the crystallographic structure of a sample at an atomic scale. In this mode, the transmitted and the diffracted beams of electrons are allowed to interfere to produce phase-contrast images.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>high resolution transmission electron microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
[definition source]: http://en.wikipedia.org
scanning transmission electron microscope
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A transmission electron microscope with which a beam of electrons pass through the specimen, where the beam is focused into a narrow spot that is scanned over the sample specimen in a raster.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>scanning transmission electron microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
scanning transmission electron microscopy
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A transmission electron microscopy technique based on the use of scanning transmission electron microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>scanning transmission electron microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
differential interference contrast microscope
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An optical microscope which generates contrast within the specimen by exploiting phase differences between a specimen (sample) light ray and a reference ray. The sample and reference rays are created after the ray traverses, and is phase-distorted by, the sample. The phased ray then is split into two equally phased, but spatially separated ("sheared") rays by the action of a Wollaston prism. Finally, the ray-pairs pass through a polarizing filter where they are vibrationally recombined and interact at the image plane. It is the wave interference of these two rays that creates contrast.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>differential interference contrast microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DIC microscope is based on interferometry, which is the technique of superposing (interfering) two or more waves, to detect differences between them. In interferometry, a single ray of light is split into two rays, one traversing and the other missing the specimen but interacting with the background. The rays are then recombined at the image plane, where wave interference may occur. Image contrast can be modified by altering the phase difference between the reference and specimen rays. [source: http://encyclopedia.thefreedictionary.com]
differential interference contrast microscopy
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An optical microscopy based on the use of differential interference contrast microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>differential interference contrast microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
nanoparticle response to external stimulus
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to stimulus, which occurs in response to the external stimulus acting on the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nanoparticle response to external stimulus</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A technique for counting, examining and sorting microscopic particles (e.g., single cells) suspended in a stream of fluid that passes through a beam of light. It allows for multiple analyses of the physical and chemical characteristics of single cells flowing through an optical and/or electrical detection apparatus.</ncicp:def-definition><ncicp:Definition_Review_Date>100617</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>flow cytometry</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
[definition: adapted from NCIT, http://encyclopedia.thefreedictionary.com]
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A light scattering technique for measuring the electrophoretic mobilities of charged particles suspended in nonpolar media (i.e. solvents with much lower relative permittivities than water).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>phase analysis light scattering</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
[definition: adapted from http://www.unisa.edu.au/laser/Research/PALS.asp]
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A technique which is used for measuring the intensity of electromagnetic radiation that is absorbed, emitted (radiated), or scattered at different wavelengths or frequencies by a molecular entity or substance. This technique is used in studying the interaction of electromagnetic radiation with matter.</ncicp:def-definition><ncicp:Definition_Review_Date>100611</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A spectroscopic technique which utilizes a laser beam to irradiate a sample containing particles in suspension, resulting in light scattering.When the scattered light is collected over a small solid angle, the light will exhibit intensity fluctuations. This is because the Brownian motion of the scatterers causes the phase of the light scattered from each particle to change with time, hence the total scattered intensity also fluctuates with time. The rapid fluctuations in scattering intensity, collected around a mean value at a certain angle, will depend on the particle diffusion and on the particle size. For a given temperature and viscosity, a calculated correlation function yields a diffusion coefficient, which can be used to calculate particle size.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>dynamic light scattering</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A pure substance which is made up of more than one type of atom, and can be decomposed into its elements by chemical methods. This class includes terms that can be used to describe molecules or compounds. A molecule is a group of atoms bonded together, representing the smallest fundamental unit of a chemical compound that can take part in a chemical reaction.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>compound or molecule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An absorption spectroscopic technique which uses NMR (nuclear magnetic resonance) to basically measure the frequency (resonant frequency) of vibrating nuclei (having non-zero spin) of a given type in the presence of a magnetic field. When placed in a magnetic field, nuclei that have non-zero spins absorb frequency characteristic of the isotope. The frequency (resonant frequency), the energy of absorption, and the intensity of measured NMR signal are proportional to the strength of the magnetic field. Nuclei of different isotopes in a substance resonate at different frequencies depending upon the local molecular geometry (bond lengths, bond angles, bonded atoms, etc.) and the local magnetic field at each nucleus. Nuclei of the same type can have slightly different resonant frequencies depending on the chemical environment. The difference between the frequency of the measured signal (NMR signal) from nuclei (in a molecule) in one sample and that (reference resonant frequency) from the same type of nuclei in a reference substance is used to obtain structural information of the molecule in a sample, or the chemical composition of the sample. This technique has applications in the study of the physical, chemical, and biological properties of matter.</ncicp:def-definition><ncicp:Definition_Review_Date>100610</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.answers.com/topic/nmr-spectroscopy (June 10, 2010), http://www.cis.rit.edu/htbooks/nmr/inside.htm (June 10, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nuclear magnetic resonance spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
Depending on the local chemical environment, different protons in a molecule resonate at slightly different frequencies. Since this frequency shift is proportional to the strength of the magnetic field, it is converted into a field-independent dimensionless value known as the chemical shift. The chemical shift is reported as a relative measure from some reference resonance frequency. (For the nuclei1H, 13C, and 29Si, TMS (tetramethylsilane) is commonly used as a reference.) This difference between the frequency of the signal and the frequency of the reference is divided by frequency of the reference signal to give the chemical shift. The frequency shifts are extremely small in comparison to the fundamental NMR frequency. A typical frequency shift might be 100 Hz, compared to a fundamental NMR frequency of 100 MHz, so the chemical shift is generally expressed in parts per million (ppm). By understanding different chemical environments, the chemical shift can be used to obtain some structural information about the molecule in a sample. The conversion of the raw data to this information is called assigning the spectrum. [source: http://encyclopedia.thefreedictionary.com]
When placed in a magnetic field, NMR active nuclei (such as 1H or 13C) absorb at a frequency characteristic of the isotope. The resonant frequency, energy of the absorption and the intensity of the signal are proportional to the strength of the magnetic field.
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which analyzes fluorescence spectra from a sample. It involves using a beam of light, usually ultraviolet light, that excites the electrons in molecules of certain compounds and causes them to emit light of a lower energy, typically, but not necessarily, visible light.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>fluorescence spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A technique to obtain the image (appearance or form) of the whole or part of a material object.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>imaging technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Imaging of structural or functional patterns of organs or tissues for the purpose of diagnostic evaluation.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>diagnostic imaging</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imaging technique in which waves of energy are passed through the sections of a solid object to obtain images of the internal structures of the object.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A qualitative measure of "ionizability" which indicates that the bearer cannot be ionized to gain negative or positive charges.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A medical tomographic technique which uses computer to construct a three-dimensional image of the internal structures of an object from a large series of two-dimensional cross-sectional X-ray images of the object, taken around a single axis of rotation.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>computed tomography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
single photon emission computed tomography
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A tomographic technique which uses radionuclides that emit single photons in the gamma energy range. The radionuclides are administered into a patient's body and the gamma rays produced by these radionuclides pass through the patient's body, which are then detected by one or more gamma cameras rotated around the patient's body. Series of two-dimensional cross-sectional images of the body, produced by this technique, can be used to create three-dimensional images by computer reconstruction.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>single photon emission computed tomography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A tomography technique for measuring the gamma radiation produced by collisions of electrons and positrons (anti-electrons) within living tissue. In positron emission tomography (PET), a subject is given a dose of a positron-emitting radionuclide attached to a metabolically active substance (for example, 2-fluoro-2-deoxy-D-glucose (FDG), which is similar to a naturally occurring sugar, glucose, with the addition of a radioactive fluorine atom). When living tissue containing the positron emitter is bombarded by electrons, gamma radiation produced by collisions of electrons and positrons is detected by a scanner, revealing in fine detail the tissue location of the metabolically-active substance administered.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>positron emission tomography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A non-invasive imaging method of creating images of internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>magnetic resonance imaging</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imaging technique in which ultrasound (sound waves with frequency above the human hearing range) waves are bounced off tissues and the echoes produce a picture (sonogram).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>ultrasound imaging</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of titanium consisting of two oxygen atoms bonded to one titanium atom via double bonds.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>titanium dioxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle, which is basically composed of titanium dioxide.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>titanium oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A substance which is a small representative portion of a whole material entity.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Chemical composition of a sample determined by the type and amount of the chemical components of a sample.</ncicp:def-definition><ncicp:Definition_Review_Date>100727</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>sample composition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A process which is the synthesis or preparation of a sample for analysis, testing or characterization.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>sample preparation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An intramolecular interaction in which two atoms share one or more electron pairs.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>covalent interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A property which inheres in or borne by a nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nanoparticle property</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
molecular component in nanoparticle formulation
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component which is identified by virtue of its molecular structure in a nanoparticle formulation.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>molecular component in nanoparticle formulation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A role which inheres in a material entity by virtue of its ability to add/modify the properties or functions of another material entity by being associated to the latter.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>functionalizing role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component in a nanoparticle formulation which adds/modifies functional properties or function of a nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>functionalizing agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
chemical component in nanoparticle formulation
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component which is identified as part of a nanoparticle formulation.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>chemical component in nanoparticle formulation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component which is identified by virtue of its molecular structure that forms part of the basic chemical make up of a nanoparticle in a nanoparticle formulation.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>molecular component in nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component which is identified as a nanoparticle based on its structure, chemical composition or function.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nanoparticle component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fiat material part identified as being the chemical make up of a material entity.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>chemical component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A small organic molecule which is bonded to other similar molecules to form a polymer.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component which occurs as repeated units linked together in a polymer chain.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>repeat unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 77.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material entity which exists in some physical state that is identifiable as a whole at continuum length scales.</ncicp:def-definition><ncicp:Definition_Review_Date>100727</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a fluid.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>fluid state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a gas.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gaseous state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a vapor.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>vapor state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a liquid.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>liquid state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a mixture.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>state of mixture</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a suspension.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>state of suspension</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a colloid.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>colloidal state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of an emulsion.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>state of emulsion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a gel.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gel state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 98.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a sol.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>state of sol</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a sold.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>solid state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a crystal.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>crystalline state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a glass.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>glassy state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a granule.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>granular state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Physical state which is characteristic of a powder.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>powdered state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process of capturing, storing, manipulating, and displaying of images.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process which is a detailed examination, analysis, or critical inspection of a subject designed to discover facts about it.[source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Pharmacological study of the process by which a drug (or drug-containing material) is absorbed, distributed, metabolized, and eliminated by the body.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>pharmacokinetics study</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
A study of what the body does to a drug or a drug-containing material (e.g., drug-loaded nanoparticle).
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Study of the characteristics, effects, and uses of drugs and their interactions with living organisms.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>pharmacological study</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electrons occupy d-orbitals.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>d-block element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Pharmacological study of the toxicity effects of a drug or drug-containing material.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>toxicology study</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A property that is characteristic of the absorption, distribution, metabolism and elimination of a drug by the body.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>pharmacokinetic property</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The time required for half of an exogenous substance to be removed from either the plasma or whole or part of the body.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>elimination half life</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
area under the plasma concentration time curve
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The area under the curve in a plot of concentration of a drug in plasma against time</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>area under the plasma concentration time curve</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The amount of drug in the body divided by its concentration in the blood.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>volume of distribution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The volume of plasma from which the drug is completely removed per unit time</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>drug clearance</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A first-order rate constant that determines the rate at which drugs are eliminated from the body.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>elimination rate constant</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The maximum concentration of an experimental substance or drug in the plasma or a target organ after dose administration. [source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The length of time it takes to reach the maximum concentration (Cmax) of an exogenous compound or drug in the plasma or a tissue after a dose is administered.[source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Fraction of the administered dose which reaches the systemic circulation and is available at the site of action.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to external stimulus, which occurs in response to ultrasound.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nanoparticle response to magnetic field</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A parameter measured or calculated in a pharmacokinetic study.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>pharmacokinetic parameter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Imaging the size, shape, surface and structural properties of tumors.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tumor imaging</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Detection of the presence or growth of tumors in the body of a human or an animal model.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>detection of tumors</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component in a nanoparticle formulation that is a bearer of imaging function and has payload agent role.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>therapeutic payload agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component in a nanoparticle formulation that is a bearer of imaging function and payload agent role.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>imaging payload agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Angiogenesis which is the formation of new blood vessels that supply oxygen and nutrients to a tumor for its growth and maintenance.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tumor angiogenesis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of inorganic molecular entities.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>inorganic nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has superparamagnetic properties.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>superparamagnetic nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polymeric nanoparticle which consists of molecular components that are pH-sensitive.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>pH-sensitive polymeric nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Diameter which inheres in a particle.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>particle diameter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 45.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of metal.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>metal oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of a metal oxide.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>metal oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of zinc oxide.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>zinc oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of zinc.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>zinc oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of copper oxide.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>copper oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of copper.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>copper oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of copper having the chemical formula Cu2O.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>copper (I) oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of copper having the chemical formula CuO.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>copper (II) oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iron oxide nanoparticle which is basically composed of iron(II,III) oxide.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>iron (II,III) oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iron oxide nanoparticle coated with dextran.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>dextran-coated iron oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
iron oxide nanoparticle coated with dextran
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of iron (III) oxide.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>iron (III) oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has spherical shape.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>spherical nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of lipid molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>lipid nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A silica nanoparticle which has fluorescent property.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>fluorescent silica nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A colorless water-soluble glutinous protein obtained from animal tissues such as bone and skin. (source: Word Net)</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of gelatin.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gelatin nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A synthetic copolymer of lactic acid and glycolic acid.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Poly(lactic-co-glycolic acid)</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
drug targeted against protein of tumor cell
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of poly(lactic-co-glycolic acid) polymer.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>PLGA nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
poly(lactic-co-glycolic acid) nanoparticle
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shape formed by the surface of a 3-dimensional object, having elliptical or circular plane sections.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ellipsoidal shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
fluorescent core-shell silica nanoparticle
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fluorescent silica nanoparticle which has a core-shell structure.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>fluorescent core-shell silica nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of hydroxyapatite.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hydroxyapatite nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is loaded with gadolinium ions.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gadolinium-loaded nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanotube which consists of a single layer or sheet of hexagonal arrays of an element or molecule, rolled into a seamless cylinder with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>single-walled nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ion of gadolinium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gadolinium ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A magnetic nanoparticle which consists of a coating agent composed of chitosan.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>chitosan-coated magnetic nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A silica nanoparticle which has a core-shell structure.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>core-shell silica nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>An abnormal mass of tissue that results from uncontrolled proliferation of cells. It performs no bodily function. It may be benign (non-cancerous) or malignant (cancerous).</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A benign or malignant tumor arising from tissues that do not include fluid areas.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>solid tumor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The pH inhering in a tumor.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tumor pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>pH of the intracellular fluid in a cell.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>intracellular pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>The fluid inside cells.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>intracellular fluid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>The body fluid outside of cells.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>extracellular fluid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>pH of the extracellular fluid.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>extracellular pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The space within a cell, which contains the intracellular fluid.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>intracellular space</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>pH of the extracellular fluid in a tumor.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tumor extracellular pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Extracellular space in a tumor, which contains the tumor extracellular fluid.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tumor extracellular space</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Cell of, or derived from, a tumor.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tumor cell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Intracellular fluid inside tumor cells.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>intracellular fluid in a tumor cell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Extracellular fluid inside a tumor.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tumor extracellular fluid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Intracellular space within a tumor cell.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>intracellular space of tumor cell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>pH of the intracellular fluid in a tumor cell.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tumor intracellular pH</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The time taken for the concentration of an exogenous substance in the blood plasma to reduce by 50%</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cirulating half life</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
thioether linkage between thiol and maleimide derivative
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thioether linkage which is formed between a thiol and a maleimide derivative, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>thioether linkage between thiol and maleimide derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A circulating half life inhering in an exogenous substance (drug, nanoparticle, imaging agent) and is exhibited when it circulates in the blood plasma for a longer time compared to a reference.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>long circulating half life</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a circulating half life longer than that of a reference substance.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>long circulating nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A receptor that is localized to the plasma membrane and may have exposure to the extracellular milieu. [source: NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cell surface receptor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cell surface receptor that binds to folic acid and reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells..</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>folate receptor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cell surface receptor which binds to extracellular polypeptide molecules triggering intracellular signaling pathways that activate various cellular responses such as cell proliferation and/or differentiation. (source:NCI)</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>growth factor receptor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A material entity [npo:MaterialEntity] that is part of a material entity but is not demarcated by any physical discontinuities.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>fiat material part</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An optical imaging technique in which images are captured based on contrast provided by the fluorescence emitted from a fluorescent molecule when excited by a light of certain wavelength.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>fluorescence imaging</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imaging technique, which encompasses many different techniques that use light of the UV to the NIR spectral region to visualize tissue optical characteristics imparted through absorption and scattering of light, as well as emission of fluorescence. [source: abstract from book chapter " Kai Licha, Contast Agents for Optical Imaging, vol. 222/2002, Contast Agents II, 2002."]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>optical imaging</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quantum dot composed of cadmium selenide.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cadmium selenide quantum dot</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which is used to label a chemical entity for purposes of identification or detection.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>labeling molecule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A labeling molecule or substance that is used to stain and color other material entities.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>fluorescent dye</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
A dye which has the property to shine or glow brightly due to fluorescence.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A labeling role played by a molecular entity when it is used for dyeing another material entity.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>dye role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A material entity which is targeted by another material entity during the process of targeting.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The process of directing a material entity to another material entity at a specific location.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An agent role which inheres in a molecule or compound that causes the stabilization of or formation of an emulsion during the process of emulsification.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>emulsifying role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process in which two immiscible liquids are mixed to form an emulsion.</ncicp:def-definition></ncicp:ComplexDefinition>
drug directed against intracellular domain of membrane receptor
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that crosses the tumor cell membrane and blocks the intracellular domain of a membrane receptor.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>drug directed against intracellular domain of membrane receptor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A substance or a portion of a substance, which has uniform physical and chemical properties.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phase which is in the solid state.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>solid phase</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phase which is in the liquid state.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>liquid phase</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phase which is in the gaseous state.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gas phase</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phase which is dispersed in a colloidal system.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>dispersed phase</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phase which is medium of dispersion for the dispersed phase in a colloid.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>continuous phase</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process in which a nanoparticle is functionalized by linking it to a molecular entity that adds or modifies the properties or functions of the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>functionalization of nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A fiat material part which forms the basic structure or central part of an object.</ncicp:def-definition><ncicp:Definition_Review_Date>100610</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An inhibitor role borne by a molecule produced by, and obtained from, certain living cells (especially bacteria, yeasts and moulds), or an equivalent synthetic molecule, which is biostatic or biocidal at low concentrations to some other form of life, especially pathogenic or noxious organisms.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>antibiotic role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
definition based on CHEBI:22582 [antibiotic]
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecule role inhering in molecule, which is structurally similar to a metabolite, which competes with it or replaces it, and so prevents or reduces its normal utilization.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>antimetabolite role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
definition based on CHEBI:35221 [antimetabolite]
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 1 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Group 1 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A function inherining in a molecule that has an essential end-directed activity to bind to other molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>binding function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process which involves the formation of a covalent bond between two bases on DNA. (NCI)</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>DNA crosslinking</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A function inhering in a molecule that has the end-directed activity to introduce its one or more alkyl groups to another molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>alkylating function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular role inhering in a molecule and is realized during the reversible inclusion of the molecule (or group) between the base pairs of a DNA strand.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>DNA intercalator role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>DNA binding which involves insertion by covalent linkage of a molecule into the double-stranded deoxyribonucleotide polymer between the internal purine and pyrimidine base pairs stacked one on another perpendicular to the double helix axis.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>DNA intercalation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A protein that yields only amino acids when hydrolyzed. It does not contain a prosthetic group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>simple protein</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
[definition source]: http://www.thefreedictionary.com, L. G. Wade Jr. Organic Chemistry 3rd Edition
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An inhibitor role inhering in a molecule that inhibits the metabolism or activity of a molecule that initiates a physiological response when combined with a receptor.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>antagonist role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An inhibition which involves interference with, or restraint of, the activities of enzymatic biotransforming chemical modifications of folic acid.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>inhibition of folic acid metabolism</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
inhibition of dihydrofolate reductase activity
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of dihydrofolate reductase.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>inhibition of dihydrofolate reductase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 32.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular role inhering in a molecule that causes the regulation of a process or the activity of another molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>regulator role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A process which is performed to modify the surface of a nanoparticle using surface modifying agents.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>surface modification of nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antitumor activity which inhibits or blocks metastasis.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>inhibition of metastasis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
inhibition of DNA topoisomerase type I activity
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of topoisomerase type I</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>inhibition of DNA topoisomerase type I activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
inhibition of DNA topoisomerase type II activity
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of topoisomerase type II</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>inhibition of DNA topoisomerase type II activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
inhibition of DNA topoisomerase activity
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of DNA topoisomerase.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>inhibition of DNA topoisomerase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
inhibition of thymidylate synthase activity
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of thymidylate synthase.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>inhibition of thymidylate synthase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An optical imaging contrast agent, which is fluorescent, and provides contrast in images captured using fluorescence imaging techniques.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>fluorescence imaging contrast agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of protein kinase</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>inhibition of protein kinase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
inhibition of protein tyrosine kinase activity
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of protein tyrosine kinase.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>inhibition of protein tyrosine kinase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular role inhering in a molecule that causes the occurrence of a process.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>agent role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 101.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A generically dependent continuant [snap:GenericallyDependentContinuant] which is 1) a constant in the equation of a curve that can be varied to yield a family of similar curves; or 2) any factor that defines a system and determines (or limits) its performance; or 3) a quantity (such as mean or variance) that characterizes a statistical population and that can be estimated by calculations from sample data.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>WordNet</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>parameter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A parameter which characterizes a wave pattern.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>wave parameter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>Amplitude of a wave pattern.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>wave amplitude</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>Frequency of a wave pattern</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>wave frequency</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>Speed of a wave pattern</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>wave speed</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a group (whole) of multiple bearers of the same or different kinds. Two or more bearers should exist together for this quality to exist. This quality derives from an individual quality common to all the bearers in the group.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>collective quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a single bearer as a whole.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>individual quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An individual quality which inheres in a single bearer AND NOT specific to the type of bearer AND inheres in other single bearers existing by themselves independently of each other. Therefore, this quality can inhere in more than one type of single bearers.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>general individual quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An individual quality which inheres in a single bearer AND specific to the type of bearer.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>specific individual quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A general individual quality which inheres in a single bearer AND NOT specific to the type of single bearer AND the bearer needs other entities (bearers or non-bearers) to exist along with it or within it to have this quality; therefore, dependent. This quality inheres in the bearer in relation to other entities.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>dependent general individual quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 53.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A general individual quality which inheres in a single bearer AND NOT specific to the type of single bearer AND the bearer do not need other entities (bearers or non-bearers) to exist along with it to have this quality; therefore independent.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>independent general individual quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A specific individual quality which inheres in a single bearer AND specific to the type of the single bearer.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>dependent specific individual quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A specific individual quality which inheres in a single bearer AND specific to the type of the single bearer AND the bearer do not need other entities (bearers or non-bearers) to exist along with it to have this quality; therefore, independent.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>independent specific individual quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Size of a tumor.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>tumor size</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Size of a particle.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>particle size</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A specific collective quality which inheres in a group of multiple bearers AND specific only to the type of bearers in the group, AND the group does not need other entities (non-bearers) to exist along with it as a whole to bear this quality.</ncicp:def-definition><ncicp:Definition_Review_Date>101029</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>independent specific collective quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A specific collective quality which inheres in a group of multiple bearers, AND specific only to the type of bearers in the group, AND the group needs other bearers to exist along with it as a whole to bear this quality.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>dependent specific collective quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A polydispersity inhering in a collection of objects based on size.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>size distribution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A polydispersity inhering in polymers based on molecular weight.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>molecular weight distribution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A size distribution inhering in particles.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>particle size distribution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An in vitro assay performed to analyze the effect of a nanoparticle formulation or other substance on plasma coagulation.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>NCL assay protocol - ITA-12 (v 1.0)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>coagulation assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A coagulation assay which is performed to measure the time it takes for the blood plasma to coagulate in a sample when the coagulation is activated by prothrombin.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>prothrombin time assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A coagulation assay which is performed to measure the time it takes for the blood plasma to coagulate when the coagulation is activated by thrombin.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>thrombin time assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
activated partial thromboplastin time assay
<ncicp:ComplexDefinition><ncicp:def-definition>A coagulation assay which is performed to measure the time it takes for the plasma to coagulate when the coagulation is activated by partial thromboplastin.</ncicp:def-definition><ncicp:Definition_Review_Date>130524</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>activated partial thromboplastin time assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A coagulation assay which is performed to measure the time taken for the plasma to coagulate in a sample when the coagulation is activated by reptilase.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>reptilase time assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An in vitro assay which is performed using purified or crude biochemical reagents in the absence of cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>NCGC assay guidelines (http://ncgc.nih.gov/guidance/glossary.html)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>biochemical assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An in vitro assay in which the analyzed sample contains live cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>NCGC assay guidelines (http://www.ncgc.nih.gov/guidance/glossary.html)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cell-based assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cell-based assay which is performed to test the cytotoxic effects of a nanoparticle formulation or other substance.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cytoxicity assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cytotoxicity assay which is performed to study the cytoxic effects of nanoparticle formulation or other substance on cell viability.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cell viability assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cell viability assay which is performed by assessing the activity of lactate dehydrogenase (a cytoplasmic enzyme) released into the cell culture supernatant, when the plasma membrane is damaged. LDH release is used as a marker of dead cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>LDH release assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 25.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>manganese atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which measures the intensity of electromagnetic radiation absorbed by a molecular entity or a substance at different wavelengths or frequencies.</ncicp:def-definition><ncicp:Definition_Review_Date>100610</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>absorption spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
Absorption spectroscopy is used to determine the presence of or amount of a particular substance in a sample from its absorption spectrum. When the sample interacts with the radiating field, the sample absorbs energy, i.e. photons, and the intensity of absorption (radiation absorbed by the sample) varies as a function of frequency, and this variation is the absorption spectrum. (references: wikipedia, May 27, 2010)
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which measures the intensity of electromagnetic radiation emitted by a molecular entity or a substance at different wavelengths or frequencies.</ncicp:def-definition><ncicp:Definition_Review_Date>100610</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>emission spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
Emission spectroscopy is used to determine the elemental composition of a material from its emission spectrum obtained by measuring the intensity of electromagnetic radiation emitted by the atoms or molecules in the material at different wavelengths. Atoms or molecules in a material undergo transition from an excited state to a lower energy state, and during this transition, and they emit photons. Each element emits (radiates) photons at a characteristic set of discrete wavelengths according to its electronic structure. Hence, by examining these wavelengths in the emission spectrum of the material, the elemental composition of the material can be determined. They are different ways to excite the atoms. (based on source: wikipedia, May 27, 2010)
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which measures the intensity of light scattered from a substance at certain wavelengths, incident angles, and polarization angles.</ncicp:def-definition><ncicp:Definition_Review_Date>100527</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>light scattering spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A disturbance which carries energy radiated from a source and which propagates through space (vacuum or space occupied by a medium) and time.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>wikipedia (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A wave which does not require a medium to travel, and hence can travel through vacuum. The wave consists of vibrating electric and magnetic fields that move at right angles to each other and to the direction of wave motion. The electric and magnetic fields are produced by the acceleration of charged particles.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://library.thinkquest.org/10796/ch8/ch8.htm (June 3, 2010), http://www.physicsclassroom.com/Class/waves/u10l1c.cfm (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>electromagnetic wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
Electromagnetic waves are characterized by any of the three physical properties: frequency, wavelength or quantum (photon) energy. Frequency of a wave is defined as the ratio of the speed of light (in vacuum) to wavelength of the wave. The quantum energy is defined as the product of the Planck's constant and the wave frequency. The range of all possible frequencies or wavelengths or energies of an electromagnetic wave is called the electromagnetic spectrum. (reference: wikipedia)
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A wave which requires a medium (e.g., air, water, solid) to travel for transmitting energy from one location to another, with no net displacement of the particles in the medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://library.thinkquest.org/10796/ch8/ch8.htm (June 3, 2010); http://www.visionlearning.com (June 8, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mechanical wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths shorter than 0.001 nm, frequencies greater than 100 EHz (1 EHz = 10^18 Hz), and energies greater than 1.24 MeV.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://hyperphysics.phy-astr.gsu.edu/hbase/ems3.html#c5 (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>gamma-ray wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths between 10 nm and 0.001 nm, frequencies between 30 PHz and 100 EHz (1 PHz - 10^15 Hz, 1 EHz = 10^18 Hz), and energies between 124 eV and 1.24 MeV. An X-ray wave has wavelength shorter than that of an ultraviolet wave and longer than that of a gamma-ray wave</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://hyperphysics.phy-astr.gsu.edu/hbase/ems3.html#c4 (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>x-ray wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths between 400 nm and 10 nm, frequencies between 300 THz and 750 THz (1 THz = 10^12 Hz), and energies between 3.1 eV and 124 eV. An ultraviolet wave has a wavelength shorter than that of a visible light wave, but longer than that of an x-ray wave.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://hyperphysics.phy-astr.gsu.edu/hbase/ems3.html#c4 (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ultraviolet wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths between 750 nm and 400 nm, frequencies between 400 THz and 750 THz (1 THz = 10^12 Hz), and energies between 1.65 eV and 3.1 eV. A visible light wave has a wavelength longer than that of an ultraviolet wave, and shorter than that of an infrared wave.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://hyperphysics.phy-astr.gsu.edu/hbase/ems3.html#c2 (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>visible light wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths between 1 mm and 750 nm, frequencies between 300 GHz and 40 THz (1 GHz = 10^9 Hz, 1 THz = 10^12 Hz), and energies between 0.00124 eV and 1.65 eV. An infrared wave has a wavelength longer than that of a visible light wave, and shorter than that of a microwave.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://hyperphysics.phy-astr.gsu.edu/hbase/ems3.html#c1 (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>infrared wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared wave which has wavelengths between 1 mm and 10 um, frequencies between 300 GHz and 30 THz (1 GHz = 10^9 Hz, 1 THz = 10^12 Hz), and energies between 0.00124 eV and 0.124 eV.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>far-infrared wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared wave which has wavelengths between 10 um and 2.5 um, frequencies between 30 THz and 120 THz (1 THz = 10^12 Hz), and energies between 0.124 eV and 0.5 eV.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mid-infrared wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared wave which has wavelengths between 2.5 um and 750 nm, frequencies between 120 THz and 400 THz (1 THz = 10^12 Hz), and energies between 0.5 eV and 1.65 eV.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>near-infrared wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths between 30 cm and 1 mm, frequencies between 1 GHz and 300 GHz (1 GHz = 10^9 Hz), and energies between 4.1 ueV and 1.24 meV. A microwave has a wavelength longer than that of an infrared wave, but shorter than that of a radiowave.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://physics.info/em-spectrum (June 3, 2010), wikipedia (June 3, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>microwave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic wave which has wavelengths longer than 30 cm, frequencies less than 1 GHz (1 GHz = 10^9 Hz). and energies less than 4.1 ueV.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>radiowave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A mechanical wave in which the particles of the medium move back and forth in a direction perpendicular to the direction in which the wave moves and transports energy.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>transverse wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A mechanical wave in which particles of the medium move back and forth in a direction parallel to the direction in which the wave moves and transports energy.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>longitudinal wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A longitudinal wave which transports energy (sound energy) produced by a vibrating object through a medium in which the back and forth motions of the particles result in regions of high (compression) and low pressure (rarefactions) in the medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>sound wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A sound wave which is transmitted through air causing a sinusoidal pressure variation in the air at a frequency within the human audible range, i.e., approximately between 20 Hz and 20 kHz.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>audible sound wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 7.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A sound wave which has frequencies above 20 kHz (upper limit of the human audible frequency range).</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ultrasound wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A process in which energy emitted by a material source travels in the form of waves, rays, or sub-atomic particles, through a material medium or through vacuum, to be ultimately absorbed by another material.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A radiation which consists of waves of energy associated with electric and magnetic fields produced by the acceleration of electric charges.</ncicp:def-definition><ncicp:Definition_Review_Date>100603</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>electromagnetic radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies greater than 100 EHz (1 EHz = 10^18 Hz), and with wavelengths shorter than 0.001 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>gamma radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies between 30 PHz and 100 EHz (1 PHz = 10^15 Hz, 1 EHz = 10^18 Hz), and with wavelengths between 10 nm and 0.001 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>x-ray radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies between 300 THz and 750 THz (1 THz = 10^12 Hz), and with wavelengths between 400 nm and 10 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ultraviolet radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which can be detected by the human eye, and it consists of waves with frequencies between 400 THz and 750 THz (1 THz = 10^12 Hz), and with wavelengths between 750 nm and 400 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>visible light radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies between 300 GHz and 400 THz (1 GHz = 10^9 Hz, 1 THz = 10^12 Hz), and with wavelengths between 1 mm and 750 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>infrared radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared radiation which consists of waves with frequencies between 300 GHz and 30 THz (1 GHz = 10^9 Hz, 1 THz = 10^12 Hz), and with wavelengths between 1 mm and 10 um.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>far-infrared radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared radiation which consists of waves with frequencies between 30 THz and 120 THz (1THz = 10^12 Hz ), and with wavelengths between 10 um and 2.5 um.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mid-infrared radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A group which is a specific atom or group of atoms attached to the carbon backbone of an organic molecule, and it is responsible for characteristic reactions of the molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>functional group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
Each functional group has its characteristic reactivity, which may be modified by its position within the molecule or by the presence of other neighbouring functional groups. (source: Functional Group Chemistry by James R. Hanson and Eddie Abel, published by Wiley, John & Sons, Incorporate 2002)
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An infrared radiation which consists of waves with frequencies between 120 THz and 400 THz (1 THz = 10^12 Hz), and with wavelengths between 2.5 um and 750 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>near-infrared radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies between 1 GHz and 300 GHz (1 GHz = 10^9 Hz), and with wavelengths between 30 cm and 1 mm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>microwave radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electromagnetic radiation which consists of waves with frequencies less than 1 GHz (1 GHz = 10^9 Hz), and with wavelengths longer than 30 cm.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>radiowave radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A radiation which consists of waves that transmit sound energy produced from a source, and the waves travel through a medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>sound radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A sound radiation which consists of waves that transmit sound energy at frequencies above 20 kHz (upper limit of the human audible frequency range)</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ultrasound radiation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity which is the capacity to do work or to exert force over a distance.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Energy associated with a moving object by virtue of its motion.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>kinetic energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Energy which is stored in an object, and that can be converted into some form of kinetic energy.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>potential energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Kinetic energy which is associated with moving electrons.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>electrical energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Kinetic energy which is associated with randomly moving atoms or molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>heat energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
arylthioether linkage between thiol and fluorobenzene derivative
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An arylthioether linkage which is formed between a thiol and a fluorobenzene derivative, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>arylthioether linkage between thiol and fluorobenzene derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Kinetic energy which is associated with the motion of electromagnetic waves produced by the acceleration of electric charges.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>light energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Light energy which is associated with the motion of infrared waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>infrared light energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Light energy which is associated with the motion of far-infrared waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>far-infrared light energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Infrared light energy which is asscoated with the motion of mid-infrared waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mid-infrared light energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Infrared light energy which is associated with the motion of near-infrared light waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>near-infrared light energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Light energy which is associated with the motion of ultraviolet waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ultraviolet light energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Light energy which is associated with the motion of visible light waves.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>visible light energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Kinetic energy which is produced by the vibrations of an object, and transported by disturbances (sound waves) traveling through a medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>sound energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Sound energy which is carried by waves (audible sound waves) traveling at frequencies (between 20 Hz and 20 kHz) that can be detected by the human ear.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>audible sound energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Sound energy which is carried by waves (ultrasound waves) that travel at frequencies above the human audible range (above 20 kHz).</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ultrasound energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by near-infrared light.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>stimulus of near-infrared light</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Potential energy which is stored in the chemical bonds of molecules, and which is released as heat energy in a chemical reaction.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>chemical energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Potential energy which is stored in interactions between the particles in the atomic nucleus.</ncicp:def-definition><ncicp:Definition_Review_Date>100608</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>nuclear energy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A technique which is used for counting cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100614</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cell counting technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cell counting technique which uses fluorescence for counting the cells.</ncicp:def-definition><ncicp:Definition_Review_Date>100614</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>fluorescent cell counting technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A fluorescence microscopic technique which uses scanning laser light to excite fluorescent dyes within a thick sample, such as a biofilm. The image is collected in two dimensions and several images can be combined in an image stack to produce a cross sectional image through a sample or to create a three-dimensional rendering of the sample. This technique is particularly useful for imaging the positioning of biological structures within a three-dimensional space.</ncicp:def-definition><ncicp:Definition_Review_Date>100614</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.nature.com/nrd/journal/v2/n2/glossary/nrd1008_glossary.html</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>confocal laser scanning microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which consists of a thick glass slide that has a chamber with a defined volume, etched with a precisely ruled grid and is used to quantify cells or cell-sized particles in suspension.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>NCI Thesaurus</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>hemocytometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to perform dynamic light scattering technique.</ncicp:def-definition><ncicp:Definition_Review_Date>100616</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>dynamic light scattering instrument</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
phase analysis light scattering instrument
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to perform phase analysis light scattering technique.</ncicp:def-definition><ncicp:Definition_Review_Date>100617</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>phase analysis light scattering instrument</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
environmental transmission electron microscope
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A transmission electron microscope which is designed to allow the scientist to both introduce various gases into and change the temperature of the specimen/sample environment. Reactions of the sample with its environment can then be directly recorded.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:def-source>NCI</ncicp:def-source><ncicp:attr>NCIT</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>environmental transmission electron microscope</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
environmental cell-transmission electron microscope
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to count and sort microscopic particles suspended in a buffer. This instrument consists of a flow cell, at least one lamp or laser, a variable number of emission detectors or photomultipliers, a system that converts analog signals to digital, and a computer to run the system and collect and analyze the data output.</ncicp:def-definition><ncicp:Definition_Review_Date>100616</ncicp:Definition_Review_Date><ncicp:def-source>NCI</ncicp:def-source><ncicp:attr>NCIT</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>flow cytometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element whose physical and chemical characteristics vary progressively within a series.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>series element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to determine the mass of a sample with a high degree of precision.</ncicp:def-definition><ncicp:Definition_Review_Date>100616</ncicp:Definition_Review_Date><ncicp:def-source>NCI</ncicp:def-source><ncicp:attr>NCIT</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>analytical balance</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>An instrument which is used to measure changes in the electrical resistance of an electrolyte solution produced by suspended nonconductive particles. Changes in resistance determine both the concentraion and size distribution of the particles.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>coulter counter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to measure the intensity of visible light.</ncicp:def-definition><ncicp:Definition_Review_Date>100617</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>NCIT</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>photometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A photometer which measures the intensity of visible light as a function of wavelength.</ncicp:def-definition><ncicp:Definition_Review_Date>100617</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>spectrophotometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectrometer which is used to determine the energy of photoelectrons emitted from the core orbitals of the elements within a few nm from the surface of a material, by irradiating the material surface with soft monochromatic X-rays.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>X-ray photoelectron spectrometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>An instrument which is used to measure zeta potential.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>zeta potential analyzer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is used to perform capillary electrophoresis.</ncicp:def-definition><ncicp:Definition_Review_Date>100617</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>capillary electrophoresis instrument</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A spectrometer which focuss high energy electromagnetic radiation toward a sample and measures the X-rays emitted from the sample.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>energy dispersive spectrometer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An instrument which is a column in which gel particles in bead form are packed to form a separation bed through which a solution containing molecules /particles and an eluant (a buffer solution) are passed for separating the molecules/particles according to differences in their sizes.</ncicp:def-definition><ncicp:Definition_Review_Date>100616</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.scribd.com/doc/6941835/gel-filtration (June 16, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>gel filtration column</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A value which is given for a variable or parameter in a data record.</ncicp:def-definition><ncicp:Definition_Review_Date>100618</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>datum value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 109.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A generically dependent continuant which can be represented using different types of numerals, and which is used for counting, measuring or computing a quantity, or for identification.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>number</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A generically dependent continuant which is used for or regarded as representing something else.</ncicp:def-definition><ncicp:Definition_Review_Date>100618</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://dictionary.reference.com/browse/symbol (June 18, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>symbol</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A symbol which represents a string of letters and numbers.</ncicp:def-definition><ncicp:Definition_Review_Date>100618</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>alphanumeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A symbol which denotes or represents a number in a language.</ncicp:def-definition><ncicp:Definition_Review_Date>100618</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A numeral which is one of the following: 1, 2, 3, 4, 5, 6, 7, 8, 9, and 0.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>arabic numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A numeral which denotes numbers as words used in the english language.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>english numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An english numeral which is basic in form, and which is used in counting and expressing how many objects are referred to. (Examples: one, two, three, one hundred, etc.)</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.sil.org/linguistics/GlossaryOfLinguisticTerms/WhatIsACardinalNumeral.htm (June 21, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cardinal numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An english numeral which expresses a group of the number specified. (examples: by the dozen, in pairs)</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.sil.org/linguistics/GlossaryOfLinguisticTerms/WhatIsADistributiveNumeral.htm (June 21, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>distributive numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An english numeral which expresses how many fold or how many times. (Examples: once, twice, thrice, ...)</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.sil.org/linguistics/GlossaryOfLinguisticTerms/WhatIsMultiplicativeNumeral.htm (June 21, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>multiplicative numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An english numeral which is used to designate positions in a sequence. (Examples: first, second, third, etc.)</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>ordinal numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>An atom is the smallest particle that retains all the chemical properties of a given element.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An english numeral which is used to express a fraction. (Examples: one-half, one-third, etc.)</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>partitive numeral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A number which is denoted by alphanumerals.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>alphanumeric number</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A number which is denoted by arabic numerals.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>numeric number</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A datum value which is expressed in numbers, and which is measured, assigned, or computed.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>quantitative value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A datum value which is non-numerical measure or estimate of something.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>qualitative value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value which is obtained by computations or calculations.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>computed value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value which is obtained by counting.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>counted value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A computed value which is a summary of the individual quantitative variable values for the statistical units in a specific group (study domains).</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://stats.oecd.org/glossary</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>statistical measure</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A statistical measure which describes the spread in a data set of numerical values for a quantitative variable.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>measure of variability</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A statistical measure which is a meaure of the middle or expected value of a data set.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>measure of central tendency</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fiat part of a dendrimer.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>fiat dendrimer part</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of central tendency which is the sum of all the numerical values in a data set divided by the numer of numerical values.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mean</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of central tendency which is the middle value of a distribution of numerical values.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>median</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of central tendency which is the most frequently occurring value in a set of numerical values.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mode</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of variability which is the average of the square of the difference between the numerical values and the mean in a data set.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>variance</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A measure of variability which is the square root of variance.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>standard deviation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value which is measured using an instrument.</ncicp:def-definition><ncicp:Definition_Review_Date>100621</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>measured value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of temperature which is measured or calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100622</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>temperature value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of size which is measured or calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>size value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Composition which refers to the types and amounts of chemical components in the core of a material entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>core composition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A solid substance which has a conductivity between that of an insulator and that of a conductor.</ncicp:def-definition><ncicp:Definition_Review_Date>100622</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>semiconductor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
carbonyl-reactive and sulfhydryl-reactive crosslinker
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A heterobifunctional crosslinker, which has a carbonyl-reactive group at one end and a sulfhydryl-reactive group at the other end.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carbonyl-reactive and sulfhydryl-reactive crosslinker</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality which indicates the presence of a hole or empty space within a material entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>hollow</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Composition which refers to the types and amounts of chemical components on the surface of a material entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface composition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An electric charge which is the net charge present on the surface of a material entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface charge</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of body weight which is measured.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>body weight value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A quantitative value of pH which is measured or calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>pH value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of zeta potential which is measured or calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>zeta potential value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of cell viability which is measured or calculated in percentage units.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>percent cell viability</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of time which is measured or calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>time value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A temporal interval which is the time during which a process continues to occur.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>duration</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>Duration in which a material entity is in contact with or exposed to something.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>time of exposure</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 103.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A dimensionless concentration notation which denotes the amount of a given substance in a total amount of 1000, 000,000 regardless of the units of measure used as long as they are the same or 1 part in10^[9].</ncicp:def-definition><ncicp:Definition_Review_Date>100625</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>parts per billion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A carboxylic acid which is composed of six carbon atoms and a sulfhydryl group at the sixth carbon atom.</ncicp:def-definition><ncicp:Definition_Review_Date>100625</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>6-mercapto-hexanoic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A mean of all the individual particle size values in a collection of particles.</ncicp:def-definition><ncicp:Definition_Review_Date>100702</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mean particle size</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>Chemical composition of a coating layer on a material surface.</ncicp:def-definition><ncicp:Definition_Review_Date>100702</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>coat composition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Chemical composition of a material layer surrounding the core.</ncicp:def-definition><ncicp:Definition_Review_Date>100702</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>shell composition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A sample which is tested for determining its physical, chemical, and functional properties in an experiment.</ncicp:def-definition><ncicp:Definition_Review_Date>100714</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>test sample</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical component in a nanoparticle formulation, which is a nanoparticle or a molecule that is conjugated to another nanoparticle or molecule in the same formulation.</ncicp:def-definition><ncicp:Definition_Review_Date>100714</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>conjugated component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical component in nanoparticle formulation which is a nanoparticle or a molecule that is fully enclosed within a nanoparticle's site that is fully bounded by the particle's constituting material.</ncicp:def-definition><ncicp:Definition_Review_Date>100714</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>encapsulated component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical component in nanoparticle formulation, which is a molecule or a nanoparticle that is trapped due to non-covalent interactions in a nanoparticle's site that is partially bounded by the particle's constituting material.</ncicp:def-definition><ncicp:Definition_Review_Date>100714</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>entrapped component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A mean value calculated from the polydispersity indices of particle or polymeric samples of the same type.</ncicp:def-definition><ncicp:Definition_Review_Date>100727</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>mean polydispersity index</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanosensor which is defined as a nanometer-scale measurement device that consists of a biologically or chemically sensitive layer, such as an immobilized receptor, antibody, or nucleic acid, that is covalently attached to an optical transducer. In the case of a receptor-based nanosensor, an interaction between the immobilized receptor and its substrate - the molecule it binds to - produces a perturbation that the optical transducer converts to an electrical signal via laser-induced fluorescence.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>fiber-optic nanosensor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Concentration of particles dispersed in a medium or in solution.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>particle concentration</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A substance which dissolves in another substance (solvent) to form a solution.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>solute</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A role inhering in a certain amount of a compound, which is realized when it is dissolved in a solvent.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>solute role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A role which inheres in a liquid compound, and it is realized when the liquid dissolves another substance (solute).</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>solvent role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A liquid mixture which is a homogenous mixture formed by dissolving a substance (solute) in a liquid (solvent).</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>solution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An aqueous solution which consists of a weak acid and its conjugate base or a weak base and its conjugate acid; and which resists any changes in its pH when a small amount of strong acid or base is added to it.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://en.wikipedia.org/wiki/Buffer_solution ( July 28, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>buffer solution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A solution which contains water as the solvent.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>aqueous solution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality which inheres in a substance by virtue of it containing water as a solvent or a medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>aqueous</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A substance which is added to an acidic or basic solution, and then modifies its pH value to a new one and then maintains that pH.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>buffer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 99.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>An aqueous solution which contains more hydrogen ions than hydroxyl ions.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>acid solution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An aqueous solution which contains more hydroxyl ions than hydrogen ions.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>alkaline solution</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An aqueous solution of sodium chloride.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>saline</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A salt whcih is composed of sodium and chloride ions.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>sodium chloride</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a solution by virtue of it having the same solute concentration as another solution.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>isotonic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A saline solution which has the same NaCl concentration as blood.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>isotonic saline</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>An isotonic saline solution which contains phosphate buffer.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>phosphate buffer saline</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Water which has been purified by distillation.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://encyclopedia.thefreedictionary.com (July 28, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>distilled water</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Water which has been purified by ion exchange process, and lacks cations from sodium, calcium, iron, copper and anions such as chloride and bromide.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://encyclopedia.thefreedictionary.com (July 28, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>deionized water</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of polydispersity index, which is calculated.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>polydispersity index value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iodoacetyl compound is an organic compound which is characterized by the presence of an iodoacetyl group. It has the structure R-C(=O)-CH2-I, where R denotes an organic group or hydrogen atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>iodoacetyl compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A realizable entity, which is defined as the ratio of the speed of light in vacuum to that in a substance. It is a measure of the speed of light in the substance.</ncicp:def-definition><ncicp:Definition_Review_Date>130524</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>refractive index</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of refractive index.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>refractive index value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity inhering in a fluid, which is defined as the fluid's resistance to flow.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>viscosity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A fluid which can hold other substances in solution or in suspension.</ncicp:def-definition><ncicp:Definition_Review_Date>100729</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>medium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A medium which contains water.</ncicp:def-definition><ncicp:Definition_Review_Date>100729</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>aqueous medum</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A medium which is used as a solvent to form a solution.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>solvent medium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A liquid medium which is used to suspend particles.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>suspending medium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quantitative value of viscosity, which is measured or calculatd.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>viscosity value</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A unit of measure, which is a standard measure of the resistance of a fluid to deformation.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>viscosity unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A viscosity unit in standard international system, which is equal to 1 pascal second</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>pascal second</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quantum dot composed of gold element</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gold quantum dot</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A core which is composed of organic molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>organic core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A core which is composed of inorganic molecular entities.</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>inorganic core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An organic core which is composed of polymers.</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>polymeric core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An inorganic core which is composed of one or more metals.</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>metallic core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An inorganic core which is composed of metal oxide.</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>metal oxide core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An inorganic core which is composed of silica (silicon dioxide).</ncicp:def-definition><ncicp:Definition_Review_Date>100817</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>silica core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An inorganic core which has semiconducting property.</ncicp:def-definition><ncicp:Definition_Review_Date>101007</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>semiconducting core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>An electrical conductivity which is intermediate between that of an insulator and a conductor.</ncicp:def-definition><ncicp:Definition_Review_Date>101007</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>semiconductivity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A shell which is made of inorganic material.</ncicp:def-definition><ncicp:Definition_Review_Date>101007</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>inorganic shell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shell which is made of organic material.</ncicp:def-definition><ncicp:Definition_Review_Date>101007</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>organic shell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 11.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>sodium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shell which is composed of a polymer.</ncicp:def-definition><ncicp:Definition_Review_Date>101010</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>polymeric shell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shell which is composed of a metal or a metal-based compound.</ncicp:def-definition><ncicp:Definition_Review_Date>101010</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>metallic shell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shell which is composed of metal oxide.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>metal oxide shell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shel which is composed of silica.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>silica shell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shell which exhibits semiconductivity.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>semiconductive shell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An inorganic core which exhibits superparamagnetism.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>superparamagnetic core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A superparamagnetic core which is composed of iron oxide.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>superparamagnetic iron oxide core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material boundary which is positively charged due to the presence of cations on the material boundary.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cationic surface</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material boundary which is negatively charged due to the presence of anions on the material boundary.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>anionic surface</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material boundary which exhibits affinity towards water molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>hydrophilic surface</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug affecting the structure, function and synthesis of DNA in tumor cells</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>drug directed against tumor DNA</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material boundary which exhibits poor affinity to water molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>hydrophobic surface</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a molecule that is covalently attached to the surfce of the nanoparticle and that adds a functionality to the nanoparticle.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface-functionalized nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A functionalizing role which inheres in a material entity that is covalently attached to the surface of a nanoparticle.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface functionalizing role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
nanoparticle surface functionalizing role
surface functionalization of nanoparticle
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A functionalization of nanoparticle which is performed on the surface of the nanoparticle.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface functionalization of nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
functionalization of nanoparticle surface
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A chemical component in nanoparticle formulation which is used to functionalize the surface of a nanoparticle.</ncicp:def-definition><ncicp:Definition_Review_Date>101027</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface functionalizing agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A nanoparticle which has a surface that is chemically modified by the attachment of a small molecule or by the replacement of a surface functional group with a different type of functional group.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface modified nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-source>NCI</ncicp:def-source><ncicp:def-definition>A nanoparticle which dissolves in water.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>water-soluble nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A coat which has affinity to water molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>hydrophilic coat</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A molecular component in a nanoparticle, which forms part or whole of nanoparticle's core.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>core component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A molecular component in a nanoparticle, which forms part or whole of the nanoparticle's shell.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>shell component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 57.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>lanthanum atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A molecular component in a nanoparticle, which forms part or whole of the coat on a nanoparticle.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>coat component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A lipid membrane which is one (lipid) molecule thick.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>lipid monolayer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A nanoparticle which is basically composed of silver element.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>silver nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A metal nanoparticle which is composed of two types of metals.</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>bimetallic nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A functional group which is located on the surface of an object (.e.g., nanoparticle).</ncicp:def-definition><ncicp:Definition_Review_Date>101028</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>surface group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A material entity which is a minute portion of matter.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>A particle which is originally obtained from its source.</ncicp:def-definition><ncicp:Definition_Review_Date>101124</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PAS71 (draft 2.0) 2010-09-21</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>primary particle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A particle which is composed of two or more primary particles held together by covalent bonds or by weak forces like Van der Waals forces or by simply physical entanglements.</ncicp:def-definition><ncicp:Definition_Review_Date>101124</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PAS 71 (draft 2.0) 2010-09-21</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>secondary particle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A level of measureable information about a variable.</ncicp:def-definition><ncicp:Definition_Review_Date>101203</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>scale of measurement</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>An interval scale is a measurement scale in which a certain distance along the scale means the same thing no matter where on the scale you are, but where "0" on the scale does not represent the absence of the thing being measured.</ncicp:def-definition><ncicp:Definition_Review_Date>101203</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.statistics.com/resources/glossary/i/intscale.php (</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>interval scale of measurement</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electrons occupy g-orbitals.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>g-block element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>An interval scale of measurement which provides numerical values for temperature in the range, 0 to 100, where a value of zero corresponds to the melting point of water, while a value of 100 corresponds to the boiling point of water.</ncicp:def-definition><ncicp:Definition_Review_Date>101203</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Celsius scale</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>An interval scale of measurement, which provides numerical values for temperature in the range, 32 to 212, where a value of 32 corresponds to the melting point of water, while a value of 100 corresponds to the boiling point of water.</ncicp:def-definition><ncicp:Definition_Review_Date>101203</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Fahrenheit scale</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A ratio scale of measurement, which provides numerical values for temperature starting from the lowest attainable value equal to zero (absolute zero).</ncicp:def-definition><ncicp:Definition_Review_Date>101206</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Kelvin scale</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A scale of measurement in which a certain distance along the scale means the same thing no matter where on the scale you are, and where "0" on the scale represents the absence of the thing being measured.</ncicp:def-definition><ncicp:Definition_Review_Date>101206</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.statistics.com/resources/glossary/r/ratioscale.php (Dec. 6, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>ratio scale of measurement</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A scale of measurement, which provides a list of categories to which objects can be classified. The data so classified are termed categorical data.</ncicp:def-definition><ncicp:Definition_Review_Date>101206</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.statistics.com/resources/glossary/n/nomscale.php (Dec. 6, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nominal scale of measurement</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A scale of measurement, which assigns values to objects based on their ranking with respect to one another.</ncicp:def-definition><ncicp:Definition_Review_Date>101206</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.statistics.com/resources/glossary/o/ordscale.php (Dec. 6, 2010)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>ordinal scale of measurement</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>An interval scale of measurement, which provides log transformed values of a measured variable.</ncicp:def-definition><ncicp:Definition_Review_Date>101206</ncicp:Definition_Review_Date><ncicp:def-source>NCI</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>logarithmic scale</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A logarithmic scale which represents log (to the base 10) values of the concentration of hydrogen ions in aqueous solutions.</ncicp:def-definition><ncicp:Definition_Review_Date>101206</ncicp:Definition_Review_Date><ncicp:def-source>NCI</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>pH scale</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>An interval scale of measurement which provides a range of values between 1 nm and a few hundred nm.</ncicp:def-definition><ncicp:Definition_Review_Date>110104</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>A nanomaterial which is designed for a specific purpose or function.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>ISO/TS 80004-1</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>engineered nanomaterial</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition which inheres in a material entity that can be decomposed by living organisms.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>A nanomaterial which has an internal nanostructure or surface nanostructure.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>ISO/TS 80004-1</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nanostructured material</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexTerm><ncicp:term-name>MTT assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A physical assay which is used to measure the size of a particle or molecule.</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>size assay</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>The generation number of a dendrimer.</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>dendrimer generation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>The size of a particle or molecule in an aqueous solution.</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hydrodynamic size</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>The hydrodynamic size which is the diameter of a particle or molecule (approximated as a sphere) in an aqueous solution.</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hydrodynamic diameter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>definition to be added</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>definition to be added.</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular role inhering in a protein molecule by virtue of the protein's function.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>protein role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>definition to be entered.</ncicp:def-definition><ncicp:Definition_Review_Date>110705</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>A technique which describes the way how a material is synthesized.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>material synthesis technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A material synthesis technique in which chemical reactions require the use of a solution.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>solution-based chemistry technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A solution-based chemistry technique in which substances are crystallized from high temperature aqueous solutions at high vapor pressures.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://en.wikipedia.org/wiki/Hydrothermal_synthesis</ncicp:attr><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hydrothermal method</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A solution-based chemistry technique for dispersing two or more immiscible liquids as micron-sized droplets by shaking, stirring or homogenising the mixture.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.rsc.org/publishing/journals/prospect/ontology.asp?id=CMO:0.0002150$MSID=b916837k</ncicp:attr><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>micro-emulsion method</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A solution-based chemical technique which ...[To be completed]</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>sol-gel chemical process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>definition [to do]</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>solvent displacement method</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexTerm><ncicp:term-name>sonochemical method</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
template-assisted solution-based synthesis
<ncicp:ComplexTerm><ncicp:term-name>template-assisted solution-based synthesis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A synthesis technique which involves the layer-by-layer deposition of individual atoms from a material source (solid, liquid, vapor or gas), onto the surface of a material (substrate).</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>thin film deposition technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quantum dot composed of zinc sulfide.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>zinc sulfide quantum dot</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A thin film deposition technique in which one or more volatile precursors react and/or decompose on the surface of the substrate.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>chemical vapor deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A chemical vapor deposition technique in which gaseous precursors chemically react with a surface in a sequential manner.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>atomic layer deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A chemical vapor deposition technique in which metal organic compounds in gas phase (at moderate pressures) react to form epitaxial layers of material on the surface of the substrate.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>metal-organic chemical vapor deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
plasma-enhanced chemical vapor deposition
<ncicp:ComplexDefinition><ncicp:def-definition>A chemical vapor deposition technique in which gaseous precursors react when a plasma of the gases is created by RF (radio frequency) or DC discharge between two electrodes.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>plasma-enhanced chemical vapor deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A chemical vapor deposition in which the substrate is heated.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>thermal chemical vapor deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A thin film deposition technique in which atoms from the surface of a solid material are vaporized by physical methods (e.g. by bombarding the solid surface with an energetic ion beam, laser beam, or electron beam), and then transported for deposition on the surface of the substrate. The deposition process takes place in under low pressure or vacuum conditions.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>physical vapor deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A physical vapor deposition technique in whcih the source material is vaporized by irradiating the target surface of the source material by a pulsed laser beam.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>pulsed laser deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A physical vapor deposition technique in which atoms from the surface of a solid material are vaporized by bombarding the surface with energetic particles (e.g., accelerated ions).</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>sputter deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A type of sputter deposition where a magnetron is used to direct the flow of high energy electrons for the sputtering process. A magnetron is a vacuum tube in which the electrons generated from a heated cathode flows under the control of an applied magnetic field.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>magnetron sputtering</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A physical vapor deposition technique in which the source material is evaporated in vacuum, and the vaporized material condenses on the surface of the substrate.</ncicp:def-definition><ncicp:Definition_Review_Date>110720</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>thermal evaporation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A physical vapor deposition in which a target anode is bombarded with an electron beam given off by a charged tungsten filament under high vacuum.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://en.wikipedia.org/wiki/Electron_beam_physical_vapor_deposition</ncicp:attr><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>electron beam physical vapor deposition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A thermal evaporation technique in which the evaporated atoms in high or ultra-high vacuum do not interact with each other until they reach the surface of the substrate. The deposition occurs at a slow rate to allow controlled growth of a monocrystalline film on a monocrystalline substrate.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>molecular beam epitaxy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A thermal evaporation technique in which heat is generated using electric conductors carrying current.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>resistive heating</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A thermal evaporation technique in which the target surface of the source material is heated by an electromagnetic field induced by a RF (radio frequency) signal.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>RF-induction technique</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A process which is conducted or occurs during the synthesis of a material.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>synthesis part</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A process which is conducted during synthesis.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>macroscopic synthesis part</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>definition: To Do</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>A solution-based chemistry technique which enables the precipitation of soluble substances.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fiat material part formed by chemically linking or associating two or more material entities (molecular entities, groups, nanomaterials) or parts thereof by molecular forces.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>vortex shaking</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 5 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Group 5 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexTerm><ncicp:term-name>surface coating</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A process which takes place during synthesis of a sample at the microscopic level.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>microscopic synthesis part</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanocage composed of gold element.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gold nanocage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
Gold nanocages, some 40 nanometers in diameter can be made by replacing the silver atoms of silver nanotubes.
<ncicp:ComplexDefinition><ncicp:def-definition>A material entity which occurs exclusively in microorganisms, plants, animals, and human beings.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>biological material entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A material entity which chemical interaction</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>chemical entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A chemical entity which can be identified based on its physical state, chemical composition or molecular structure.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>chemical substance</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A chemical substance which as a constant, defined composition and cannot be separated into simpler substances by physical methods.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.teacherbridge.org/public/bhs/teachers/Dana/Matter.html</ncicp:attr><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>pure substance</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A biological material entity which is fluid-like.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>biological fluid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A biological material entity which is a small molecule or a macromolecule.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>biological molecule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which is identified based on its application.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>compound by application</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which is identified based on its chemical composition.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>compound by chemical composition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which has specific properties that makes it useful for imaging applications.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>compound for imaging</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 4.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which plays a role in material synthesis.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>compound for material synthesis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which is used for targeting other molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>compound for targeting</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which is used for therapeutic applications.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>compound for therapy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>To be defined</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>journal article</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>string datatype</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>integer datatype</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>floating point datatype</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>floating point</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A collection of processes that leads the way for blood coagulation to take place.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>blood coagulation pathway</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A chemical substance which has atleast one external dimension or internal structure or surface structure in the nanoscale size range.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>ISO/TS 80004-1</ncicp:attr><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
[Previous definition]: A material entity which is synthesized, characterized, and which has at least one spatial size dimension distinguishable in the nanoscale (1-100 nm) range.
<ncicp:ComplexDefinition><ncicp:def-definition>To be defined.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>intrinsic pathway of blood coagulation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexTerm><ncicp:term-name>extrinsic pathway of blood coagulation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
final common pathway of blood coagulation
<ncicp:ComplexTerm><ncicp:term-name>final common pathway of blood coagulation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>Time needed for blood coagulation to occur.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>blood coagulation time</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexTerm><ncicp:term-name>activated partial thromboplastin time</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexTerm><ncicp:term-name>prothrombin time</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexTerm><ncicp:term-name>thrombin time</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>an instrument which is used to measure the time required for a sample of fluid (blood) to coagulate.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>A biological material entity that is analyzed in a bioassay.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>biological specimen</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>An instrument which is a machine that uses centrifugal force to separate substances of different densities or to remove moisture.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>http://www.merriam-webster.com (last accessed: November 6, 2011)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition, inhering in any material entity, whose structure or function can be altered by changes in pH of the medium containing it.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>A technique used for incubating mixtures in an assay.</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>DNA topoisomerase type I activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 87.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>francium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular role which inheres specifically in a a chemical component of a nanoparticle formulation with respect to its use in the formulation of nanoparticles.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>component role in nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The hydrophobic space within the lipid bilayer.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hydrophobic core of lipid bilayer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aryl halide group containing an aromatic benzene ring attached to one or more fluorine atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>fluorobenzene group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 55.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>caesium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A series element which is an alkali earth metal or alkali metal or inner transition element or transition element or other metal.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A linkage in which two molecular entities or parts thereof are joined to form a chemically conjugated molecular entity.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a sulfonamide group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>sulfonamide linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 28.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nickel atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An independent continuant which describes a 2-dimensional, inner/outer surface of a material entity. The material boundary separates a material entity in its identity from other surrounding material entities.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>material boundary</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 80.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a coating agent composed of polymer.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>polymer-coated nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by electric field.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>stimulus of electric field</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A non-metal which is any of the following elements: carbon, nitrogen, oxygen, phosphorus, selenium, sulfur.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>other non-metal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure N#C-S-. The group is characteristic of a thiocyanate organic molecule wherein it is attached to an organic group via a single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>thiocyanate group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 9.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>fluorine atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A permanent dipole-dipole interaction between a hydrogen atom of -OH or -NH part of a molecule and a small, highly electronegative atom of the other polar molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hydrogen bonding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular structure which describes an interior layer, formed around the dendrimer core by the addition of dendrimer branches.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>dendrimer generation layer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 41.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>niobium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A nano-object which has two external dimensions in the nanoscale (between 1 and 1000 nm) range.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>two-dimensional nano-object</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A targeting agent, which is a ligand or small molecule that binds to larger molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>targeting ligand</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An inorganic compound or molecule which is composed of cadmium and selenium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cadmium selenide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -E(=O)-NH2 or -E(=O)-NH- or -E(=O)-N(-)-, where E could denote one of the following atoms: carbon (C), sulfur (S) or phosphorus (P). The group is characteristic of an amide compound wherein it is attached to organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>amide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an isothiourea group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>isothiourea linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 5.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group, the structure of which consists of a saturated cyclic ring made up of four carbon atoms and one nitrogen atom; and each of the two carbon atoms, adjacent to the nitrogen atom, are bonded to an oxygen atom via a double bond, while the nitrogen atom is bonded to one oxygen atom of the carbonate group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>succinimidyl carbonate group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>DNA crosslinking agent, which alkylates DNA.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>DNA alkylating agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
carbamate ester linkage between primary amine and carbonate ester
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carbamate ester linkage which is formed between a primary amine and a carbonate ester, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carbamate ester linkage between primary amine and carbonate ester</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an amidine group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>amidine linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as an explosive device.</ncicp:def-definition></ncicp:ComplexDefinition>
An explosive device comprised of carbon nanotubes. These nanoscale devices have desirable optical and thermal properties that can be exploited for novel cancer therapeutics. The ability to manipulate these properties facilitates a controlled, localized activation and clearance mechanism of diseased or abnormal cells.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an isourea group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>isourea linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spheroidal shape, which is generated by half-revolution of an ellipse around its minor axis.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>oblate spheroidal shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aminoacid which can become ionized.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>ionizable aminoacid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 66.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 86.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Outer surface of a liposome vesicle, formed by the polar head groups of lipid molecules that compose the lipid bilayer.</ncicp:def-definition><ncicp:Definition_Review_Date>101026</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>outer hydrophilic surface of liposome</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 10.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>neon atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an imide group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>imide linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 61.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>promethium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 12.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 20.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound of biological origin, which contains hydrocarbons and it is insoluble in water but soluble in non-polar solvents.</ncicp:def-definition></ncicp:ComplexDefinition>
[ChEBI definition]: A loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids.
[NCI_Thesaurus definition]: A class of hydrocarbon-containing organic compounds. Lipids are insoluble in water but soluble in nonpolar solvents and play important roles in living organisms: these roles include functioning as energy storage molecules, serving as structural components of cell membranes, and constituting important signaling molecules. Lipids can be subdivided into 2 groups: fatty acids and glycerides.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 91.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A series element which is not a metal.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>non-metal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Enzyme inhibitor that inhibits the enzymatic activity of topoisomerases.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>topoisomerase inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 9.</ncicp:def-definition></ncicp:ComplexDefinition>
hydrophilic space between lipid bilayers
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The aqueous space between lipid bilayers (e.g, in a multilamellar vesicle).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hydrophilic space between lipid bilayers</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of chitosan</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>chitosan nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
(definition source): http://dictionary.reference.com/browse/antiferromagnetic
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Magnetic property exhibited in materials where the magnetic moments of adjacent atoms align in opposite directions, and this quality exists only below the Neel temperature.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A brittle transparent solid substance with irregular atomic structure.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=O)-N(-)-N(-)-. The group is characteristic of a carbohydrazide compound.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carbohydrazide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 13 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Group 13 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 60.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -O-. The group is characteristic of an ether in which the oxygen atom is attached to two carbon atoms via single covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>ether group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A three-dimensional nanoparticle which is composed of a spherical core surrounded by a shell of a few nanometer in thickness. If the shell is made of metal particles, then it is called a metallic nanoshell (e.g. Gold nanoshell).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 6 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Group 6 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A nano-object which has all three external dimensions in the nanoscale (between 1 and 1000 nm) range.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>three-dimensional nano-object</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of iron.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>iron oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Quality which exactly or approximately describes the external form or outline of something as distinct from its substance.</ncicp:def-definition></ncicp:ComplexDefinition>
The spatial arrangement of something as distinct from its substance. [source: NCI, WordNet]
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 55.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a chemical substance due to the presence of a cyclically conjugated molecular entity , with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure.</ncicp:def-definition></ncicp:ComplexDefinition>
Definition of aromatic is based on that of an aromatic compound (CHEBI:33655)
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 80.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>mercury atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a secondary amine group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>secondary amine linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The core part of a dendrimer, which is formed by the core initiator group [npo:NPO_803].</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>dendrimer core</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 14 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Group 14 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Role of a molecular entity, which brings about an end therapeutic result in cancer therapy.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>anticancer drug role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 105.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>A chemical substance which is composed of two or more substances (with variable composition) that are not chemically combined with each other and are capable of being separated hy physical means.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has two external dimensions in the nanoscale size range.</ncicp:def-definition><ncicp:Definition_Review_Date>110104</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>two-dimensional nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An ellipsoidal shape inhering in 3-dimensional object, where every point on the surface is equidistant from the center of the object.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>spherical shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 31.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 73.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A substance or compound, which is used to produce a chemical reaction, to detect, measure, or produce other substances; or to convert one substance into another by chemical reaction.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
hydrazone linkage between carbohydrazide and aldehyde
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrazone linkage which is formed between a carbohydrazide and an aldehyde, through covalent interactions between atoms of respective functional groups..</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hydrazone linkage between carbohydrazide and aldehyde</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>Role played by a substance or compound used to produce a chemical reaction to detect, measure, or produce other substances.</ncicp:def-definition><ncicp:Definition_Review_Date>100730</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>reagent role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
drug that affects protein activity related to DNA synthesis
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that is directed against a tumor cell to inhibit a protein activity related to the synthesis of DNA.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>drug that affects protein activity related to DNA synthesis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
sulfonamide linkage between primary amine and sulfonyl chloride derivative
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A sulfonamide linkage which is formed between a primary amine and a suflonyl chloride derivative, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>sulfonamide linkage between primary amine and sulfonyl chloride derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
cellular uptake of extracellular material
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A biological process or mechanism by which extracellular materials are taken up by a cell.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cellular uptake of extracellular material</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 30.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>zinc atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 19.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>potassium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A double-walled nanotube which consists of two graphite layers or sheets of hexagonal arrays of carbon, rolled into two concentric seamless cylinders with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>double-walled carbon nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 93.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>neptunium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 17.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>chlorine atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An inorganic compound or molecule which is composed of zinc and sulfur.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>zinc sulfide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cylindrical shape inhering in 3-dimensional object with height smaller than the cross-sectional diameter.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>disc-shaped</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
anticancer drug directed against endothelial growth factor
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that is directed to affect the synthesis and function of endothelial growth factor.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>anticancer drug directed against endothelial growth factor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element that has the same number of electron shells as other elements of a horizontal row in the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>period element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
amide linkage between primary amine and acid anhydride
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide linkage which is formed between a primary amine and an acid anhydride.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>amide linkage between primary amine and acid anhydride</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which has the intended function to furnish pharmacological activity or other direct effect in the cure, mitigation, treatment or prevention of cancer.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>anticancer drug</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An attractive type of chemical interaction that holds atoms together in a molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>intramolecular interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 13.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antimitotic agent, which binds to tubulin and inhibits its action.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tubulin binding agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The hollow core region of a nanocapsule.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hollow core of nanocapsule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 84.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Metastasis is the spread or migration of cancer cells from one part of the body (the organ in which it first appeared) to another. The secondary tumor contains cells that are like those in the original (primary) tumor. For example, breast cancer cells may spread (metastasize) to the lungs and cause the growth of a new tumor. When this happens, the disease is called metastatic breast cancer. (NCI)</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An ellipsoidal shape, which is generated by half-revolution of an ellipse around its major axis or minor axis.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>spheroidal shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -N=C=O. The group is characteristic of a isocyanate compounds wherein it is attached to an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>isocyanate group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A supramolecular structure which is a membrane composed of lipid molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>lipid membrane</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 105.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>dubnium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 25.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A diagnostic imaging agent, which is used during an imaging procedure to allow the delineation of biological structures in their images. Contrast agents appear opaque due to the difference in absorption of X-rays or other electromagnetic waves and surrounding tissue.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>contrast agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -[N+]#N. The group is characteristic of diazonium compounds.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>diazonium group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic agent,which regulates DNA-dependent transcription.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>DNA-RNA transcription regulator</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 10.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A diazonium compound is an organic compound which is characterized by the presence of a diazonium group. It has the structure R-[N+]#N, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>diazonium compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Magnetic property exhibited by materials in presence of an external magnetic field and in these materials the magnetic moment of the atoms on different sublattices are opposed, and the opposing magnetic moments are unequal, and therefore, a spontaneous magnetization remains. This property exists below the Curie temperature.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An inner transition element which is any element with atomic numbers 57 (lanthanum) to 71 (Lutetium).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 88.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>radium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 24.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 92.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>uranium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which is formed and held together by non-covalent interactions of molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>supramolecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A lipid membrane which is two (lipid) molecules thick.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>lipid bilayer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A halo group in which the halogen atom is a bromine atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>bromo group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imidoester compound is an organic compound which is characterized by the presence of an imidoester group. It has the structure R-C(=[NH2]+)-O-CH3, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>imidoester compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 40.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>zirconium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An elliptical shape in which the two foci are coincident that it is formed by a closed curve that is the path, traced by a point moving in a plane so that its distance from a fixed point (the circle's center) is a constant.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>circular shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
[definition based on source]:http://www.cycfoundation.org, http://www.thefreedictionary.com, NCI
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dipole-dipole interaction between a polar molecule and a non-polar molecule due to attraction between permanent dipole on the polar molecule and temporary dipole on the non-polar molecule; the temporary dipole on the non-polar molecule is induced by the permanent dipole on the polar molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>dipole-induced dipole interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
It occurs when a non-polar molecule dissolves in a polar or a dipolar solvent under the assumption that the solute dissolves because the attractive force between the solvent and solute are stronger than the intermolecular forces, holding the non-polar solute molecules together.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which consists of an aromatic ring bonded to one or more halogen atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>aryl halide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which consists of a nitrogen atom bonded to two adjacent carbon atoms in the form of a 3-membered saturated ring structure; it has the structure C1-C-N1. And the group is characteristic of any aziridine derivative.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>aziridine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 37.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>rubidium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 62.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 76.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>osmium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 37.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule, in which carbon is not the principal element.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>inorganic compound or molecule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 101.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>mendelevium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A multi-walled nanotube which consists of multiple graphite layers or sheets of hexagonal arrays of carbon, rolled in on themselves to form concentric seamless cylinders with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>multi-walled carbon nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexTerm><ncicp:term-name>nanoparticle response to ultrasound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A group that forms the sidechain of an alpha-aminoacid.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>alpha-aminoacid sidechain</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 4 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Group 4 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 97.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A suspension of particles (dispersed phase) in a liquid medium (dispersion medium or continuous phase).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A material site which is in the core of a material entity; which is hollow or a void space, into which molecular agents like drugs, imaging agents, etc. can be placed.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>core site</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 59.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>praseodymium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 72.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hafnium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 107.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 83.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>bismuth atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aziridine derivative is an organic compound which is characterized by the presence of an aziridine group. It has the structure R-C1H-CH2-C1H, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>aziridine derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 15.</ncicp:def-definition></ncicp:ComplexDefinition>
linkage between primary amine and isothiocyanate
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An isothiourea linkage which is formed between a primary amine and an isothiocyanate, through covalent interactions between atoms of respective functional groups..</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>linkage between primary amine and isothiocyanate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 38.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>strontium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 15 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Group 15 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
isourea linkage between primary amine and isocyanate
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An isourea linkage which is formed between a primary amine and an isocyanate, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>isourea linkage between primary amine and isocyanate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 50.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tin atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 45.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>rhodium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A contrast agent, which has optical properties, and provides contrast in images captured using optical imaging techniques.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>optical imaging contrast agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 64.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 44.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>ruthenium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A two-dimensional nano-object which has a wire-like structure made of materials that exhibit unique electrical and optical properties.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 67.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A non-covalent interaction which is a repulsive interaction between hydrophobic molecule or hydrophobic part of an amphiphilic molecule and water molecules in aqueous solutions. It results from energetically favorable interactions between hydrophilic molecules or parts there of and water molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hydrophobic interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
arylamine linkage between primary amine and fluorobenzene derivative
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An arylamine linkage which is formed between a primary amine and a fluorobenzene derivative, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>arylamine linkage between primary amine and fluorobenzene derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic antimetabolite which affects the metabolism and utilization of pyrimidines.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>pyrimidine antagonist</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amidine group which has the structure -C(=N-)-NH2. It is characteristic of a carboxamidine compound.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carboxamidine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle formulation which exists as an emulsion and contains nanoparticles as the dispersed phase.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide group which has the structure -C(=O)-N(-[*])-C(=O)-. The group is characteristic of an imide compound.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>imide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is loaded with a drug.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>drug-loaded nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 103.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>lawrencium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanotube which consists of two layers or sheets of hexagonal arrays of an element or molecule, rolled into two concentric seamless cylinders with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>double-walled nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 3.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>lithium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of gold element.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gold nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cyanate is an organic compound which is characterized by the presence of a cyanate group. It has the structure R-O-C#N, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 5.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>boron atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 39.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>yttrium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure R-C(=O)-[N+]#N, where R denotes any organic group. The group is characteristic of acyl azide compounds.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>acyl azide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
The structure of an acyl azide is R-C(=O)-[N+]#N, in which an acyl group is bound to a diazonium group.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The central part of a nanocell.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nuclear core of nanocell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electrons occupy f-orbitals.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>f-block element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
epidermal growth factor receptor tyrosine kinase inhibitor
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Tyrosine kinase inhibitor, which inhibits Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase, involved with signal transduction pathways, and may be useful in treating tumors that over express EGFR. [source:NCI_Thesaurus]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>epidermal growth factor receptor tyrosine kinase inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality that inheres in a molecule or chemical bond due to the presence of dipole moments.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>A nano-object which has only one external dimension in the nanoscale (between 1 and 1000 nm) range.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>one-dimensional nano-object</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by light.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>stimulus of light</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 56.</ncicp:def-definition></ncicp:ComplexDefinition>
thioether linkage between thiol and acryloyl compound
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thioether linkage which is formed between a thiol and an acryloyl compound, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>thioether linkage between thiol and acryloyl compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
hydrazone linkage between carbohydrazide and ketone
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrazone linkage which is formed between a carbohydrazide and a ketone, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hydrazone linkage between carbohydrazide and ketone</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 1.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hydrogen atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 29.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A metal which is either an actinide or a lanthanide.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>inner transition element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity that describes the ability of an atom in a molecule to draw bonding electrons to itself.</ncicp:def-definition></ncicp:ComplexDefinition>
[definition source]: http://hyperphysics.phy-astr.gsu.edu/Hbase/hframe.html
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 51.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 75.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A halo group in which the halogen atom is a iodine atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>iodo group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A qualitative measure of "ionizability" which indicates that the bearer can be ionized to gain negative or positive charges.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carbonate ester is an organic compound which is a diester derivative of carbonate and it is characterized by the presence of a "carbonate ester group." It has the structure R-O-C(=O)-O-R', where R, R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carbonate ester</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a hydrazone group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hydrazone linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imide group derived from maleimide by the removal of a hydrogen atom that was attached to nitrogen atom of the parent maleimide. The group is characteristic of any maleimide derivative.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>maleimide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 49.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A liposome vesicle that has more than one lipid bilayer, and the bilayers are separated by hydrophilic spaces.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>multilamellar vesicle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
2-(2,6-dioxopiperidin-3-yl) isoindoline-1,3-dione [source: IUPAC]
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A synthetic derivative of glutamic acid (alpha-phthalimido-glutarimide) with teratogenic, immunomodulatory, anti-inflammatory and anti-angiogenic properties. Thalidomide acts primarily by inhibiting both the production of tumor necrosis factor alpha (TNF-alpha) in stimulated peripheral monocytes and the activities of interleukins and interferons. This agent also inhibits polymorphonuclear chemotaxis and monocyte phagocytosis. In addition, thalidomide inhibits pro-angiogenic factors such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), thereby inhibiting angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition>
Anticancer Drug Directed Against Endothelial Growth Factor Receptor
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An enzyme inhibitor, which inhibits thymidylate synthase, an enzyme that catalyses the de novo synthesis of deoxythymidylate and acts as a key rate-limiting enzyme of DNA synthesis.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>thymidylate synthase inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
anticancer drug that modifies expression of specific genes
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that is directed against a tumor cell to modify the expression of specific genes.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Anticancer drug that modifies expression of specific genes</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 2.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>helium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 14.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anti-adhesion agent, which inhibits lectin, a protein that binds carbohydrate on cell surfaces and causes cell agglutination.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>lectin inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aryl halide derived from fluorobenzene.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>fluorobenzene derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic agent, which binds to an enzyme and decreases or blocks the enzyme's activity by hindering the normal substrate-enzyme combination and the catalytic reaction.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>enzyme inhibitor drug</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
Only those enzyme inhibitors that are used as cancer drugs should be included under this class.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 36.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>krypton atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 17 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Group 17 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A two-dimensional nano-object which is a capillary tube with diameter in the nanometer range. Nanopipettes made from standard quartz capillary tubes are known to detect single molecules which are labeled with gold nanoparticles.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of group 1 (IUPAC style) of the periodic table: lithium (Li), sodium (Na), potassium (K), rubidium (Rb), caesium (Cs), and francium (Fr).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>alkali metal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -N=C=S. The group is characteristic of an isothiocyanate compound wherein it is attached to an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>isothiocyanate group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a thioester group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>thioester linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanocantilever which is composed of gold.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gold nanocantilever</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 46.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a carbamate ester group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carbamate ester linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A two-dimensional nanoparticle which resembles a fullerene-like nanostructure and exhibits an irregular horn-like shape.</ncicp:def-definition></ncicp:ComplexDefinition>
[NCI_Thesaurus definition]: A fullerene-like nanostructure that consists of graphene cylinders and exhibits an irregular horn-like shape.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 70.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>ytterbium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A metal which is any of the following elements: aluminium, bismuth, gallium, indium, lead, hallium, tin.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>other metal</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic antimetabolite which interferes with folic acid metabolism by inhibiting one or more folate-dependent enzymes, resulting in decreased DNA, RNA and protein synthesis. It has a chemical structure similar to folic acid, a key component in cell proliferation,</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>folate antagonist</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A cylindrical shape inhering in a 3-dimensional object having height greater than the cross-sectional diameter.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>rod-shaped</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 18 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Group 18 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is loaded with etoposide.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>etoposide-loaded nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
carboxylic ester linkage between organo hydroxy compound and acid anhydride
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carboxylic ester linkage which is formed between an organo hydroxy compound and an acid anhydride, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carboxylic ester linkage between organo hydroxy compound and acid anhydride</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 62.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>samarium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Role that inheres in or borne by an independent continuant at the molecular level in a particular context.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>molecular role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic molecule or compound, which consists of two or more amino acids linked by covalent bonding between the amino group of one aminoacid and the carboxyl group of the other.</ncicp:def-definition></ncicp:ComplexDefinition>
anticancer drug acting in extracellular matrix
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that acts in the extracellular matrix</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>anticancer drug acting in extracellular matrix</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A linkage in which a molecular structure or nanostructure becomes trapped due to non-covalent interactions, in a nanoparticle's material site that is partially bounded by the particle's constituting material.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The hollow core of a nanoshell</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hollow core of nanoshell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
drug directed against protein of tumor cell
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that is directed to interfere with the activity of a protein located at the tumor cell.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>drug directed against protein of tumor cell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 60.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>neodymium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of a group of elements in the periodic table, which have similar outer shell electronic configurations of their respective atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>group element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A DNA binding agent that is capable of inserting itself between the successive bases in DNA, thus kinking, uncoiling or otherwise deforming it and therefore preventing its proper functioning.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>DNA intercalating agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by ultrasound.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>stimulus of ultrasound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element in the third row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Period 3 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 109.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>meitnerium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unilamellar vesicle, which has size less than 100 nm.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>small unilamellar vesicle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 31.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gallium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Surface of a micelle formed from polar head groups of constituting amphiphilic molecules in a polar solvent.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>surface of micelle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A flexible molecular part that connects two other parts of the same molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 23.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic agent that inhibits the biosynthesis of pyrimidine or purine nucleotides or mimic natural nucleotides so they interfere with their synthesis or function and subsequently interrupt DNA, RNA, and/or protein synthesis.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>antineoplastic antimetabolite</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 110.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable property which inheres in a solid, liquid, or gaseous chemical substance by virtue of a certain amount of the bearer to have the ability to dissolve or not in a certain volume of a liquid solvent to form a homogeneous solution.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity that inheres in a material entity and indicates that the bearer has the ability to produce or elicit an immune response.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An intramolecular interaction between positive and negative ions which are formed by the transfer of one or more valence electrons from one atom to another atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>ionic bonding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 74.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tungsten atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A protein that is located on the cell surface, or in the cytoplasm, and which binds to, or responds to, a ligand with high specificity. [based on source: UniProtKB]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 81.</ncicp:def-definition></ncicp:ComplexDefinition>
drug directed against protein in cytoplasm
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that is directed to interfere with the activity of a protein located in the tumor cell cytoplasm</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>drug directed against protein in cytoplasm</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 73.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tantalum atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Magnetic property exhibited in a material only when the material is kept in the presence of an externally applied magnetic field, and the magnetism disappears when the magnetic field is removed. The magnetic moments of the atoms are not aligned, and the behavior causes the material to be attracted to external magnetic fields. This behavior exists only above the Curie or Neel Temperature.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Solubility which describes the ability of a certain amount of solid, liquid or gaseous chemical substance to dissolve in a certain volume of water solvent.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>solubility in water</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 51.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>antimony atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amine group which is formally derived by the removal of one hydrogen atom from ammonia, by virtue of which it has the structure -NH2. The group is characteristic of a primary amine molecule wherein it is attached to hydrocarbyl groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>primary amine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a thioether group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>thioether linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acyl halide group in which the halogen atom is a fluorine atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>acyl fluoride group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
imine linkage between primary amine and aldehyde
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imine linkage which is formed between a primary amine and an aldehyde, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>imine linkage between primary amine and aldehyde</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amine group which is formally derived by the removal of three hydrogen atoms from ammonia, by virtue of which it has the structure -N(-)-. The group is characteristic of a tertiary amine molecule wherein it is attached to hydrocarbyl groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tertiary amine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
anticancer drug directed against endothelium
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that is directed to affect the tumor endothelial cells.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>anticancer drug directed against endothelium</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An endothelial-specific integrin inhibitor that acts by blocking the action of an endothelial cell-surface expressed alpha (v) integrin, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>alpha V beta inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acyl compound is an organic compound which is characterized by the presence of an acyl group R-C(=O)-, where R denotes an organic group and the carbon atom is not bonded to a hydrogen atom or oxygen atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>acyl compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 96.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>curium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A qualitative measure of solubility in water which indicates that the chemical substance dissolves in water under specific conditions.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>soluble in water</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shape formed by the surface of a 3-dimensional object that tapers from a circular base.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>conical shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 63.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 79.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An isocyanate is an organic compound characterized by the presence of isocyanate group. It has the structure R-N=C=O, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>isocyanate compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 1.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 84.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>polonium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
drug directed against extracellular domain of membrane receptor
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that blocks the extracellular domain of the membrane receptor.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>drug directed against extracellular domain of membrane receptor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The shell of a nanocapsule.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>shell of nanocapsule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 77.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>iridium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an imine group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>imine linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to internal stimulus, which occurs in response to a change in pH.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nanoparticle response to pH change</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A metal which is any of the following elements: d-block element or one of the elements in groups 4, 5, 6, 10, 11, 12.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>transition element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A maleimide derivative is an imide derived from maleimide by replacing the hydrogen atom bonded to nitrogen in maleimide by an organic group. It is characterized by the presence of a maleimide group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>maleimide derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 86.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>radon atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A mixture in which fine particles are suspended in a fluid where they are supported by buoyancy.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>WordNet</ncicp:attr><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 111.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>roentgenium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 85.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>astatine atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 34.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>selenium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=N-)-. The group is the characteristic of an imine.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>imine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a coating agent composed of a carbohydrate.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carbohydrate-coated nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 66.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>dysprosium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 14.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>silicon atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Role played by a molecular entity that is used to target a material entity, and the role is realized during the process of molecular targeting.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>targeting role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unilamellar vesicle, which has size greater than 100 nm.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>large unilamellar vesicle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure C(=[NH2+])-O-CH3. The group is characteristic of an imidoester compound.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>imidoester group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
anticancer drug directed against tumor cell
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug directed against a tumor cell to affect its division and function.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>anticancer drug directed against tumor cell</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
gold quantum dot-entrapped poly(amidoamine) dendrimer nanoparticle
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of poly(amidoamine) dendrimer in which gold quantum dots are entrapped.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gold quantum dot-entrapped poly(amidoamine) dendrimer nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of protein made by B lymphocytes in response to a foreign substance (antigen). Each antibody only binds to a specific antigen, helping to destroy the antigen directly or by assisting white blood cells to destroy the antigen.[source: NCI_Thesaurus]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Magnetic property exhibited in materials which create a weak magnetic field in opposition to an externally applied magnetic field; thus, causing repulsion of the material in a magnetic field.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 100.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>fermium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electrons occupy some orbital.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>block element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Tubulin binding agent that binds to the taxane site of the beta-tubulin subunit, a region described as a binding pocket located within the middle domain and corresponding to an approximate residue sequence of 217-231. Specifically, these agents bind to a cysteine residue within the pocket, which is also the binding site for GTP. Agents binding at the taxane site promote the polymerization of dimers to form a very rigid and stable microtubule structure which is not readily disassembled. Interfering with microtubule dynamics, these agents inhibit the normal turnover process essential during mitosis, thereby causing cell-cycle arrest and/or apoptosis. [source: NCIT]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>taxane-pocket binding agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 49.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>indium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 41.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thioyanate compound is an organic compound which is characterized by the presence of a thiocyanate group. It has the structure R-S-C#N, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>thiocyanate compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 78.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>platinum atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug that is directed to affect the synthesis and function of a receptor of an endothelial growth factor.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>anticancer drug directed against endothelial growth factor receptor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An attachment formed via covalent bonding between chemical groups of molecular entities.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>covalent linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process that prevents or inhibits the maturation ,growth or spread of tumor cells.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>antineoplastic activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process, which describes the function or activity of a nanoparticle, occurring in response to a stimulus acting on the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nanoparticle response to stimulus</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ionizable property inhering in a chemical substance by virtue of having the ability to be ionized and gain a positive charge.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>ionizable to gain positive charge</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A protein kinase inhibitor, which inhibits tyrosine kinase enzyme, involved with the transduction and processing of many extracellular and intracellular signals including cell proliferation.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tyrosine kinase inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 26.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 111.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 23.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>vanadium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Anticancer drug which is directed to interfere with the synthesis, function or activity of mRNA.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>drug directed against tumor RNA</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Role borne by a molecular entity which prevents or slows down an activity or process; or that reduces the activity of another molecular entity.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>inhibitor role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A recombinant, chimeric monoclonal antibody directed against the epidermal growth factor receptor (EGFR) with antineoplastic activity. Cetuximab binds to the extracellular domain of the EGFR, thereby preventing the activation and subsequent dimerization of the receptor; the decrease in receptor activation and dimerization may result in an inhibition in signal transduction and anti-proliferative effects. This agent may inhibit EGFR-dependent primary tumor growth and metastasis. EGFR is overexpressed on the cell surfaces of various solid tumors.[source: NCI_Thesaurus]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 59.</ncicp:def-definition></ncicp:ComplexDefinition>
imine linkage between secondary amine and aldehyde
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imine linkage which is formed between a secondary amine and an aldehyde, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>imine linkage between secondary amine and aldehyde</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An intermolecular interaction between molecules (polar or non-polar) due to attraction between permanent or temporary molecular dipoles.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>dipole-dipole interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polypeptide, which is part of some protein molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>polypeptide chain</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 108.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 71.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>lutetium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
(NCI_Thesaurus definition): Nanometer-sized semiconductor particles, made of cadmium selenide (CdSe), cadmium sulfide (CdS) or cadmium telluride (CdTe) with an inert polymer coating. The semiconductor material used for the core is chosen based upon the emission wavelength range being targeted: CdS for UV-blue, CdSe for the bulk of the visible spectrum, and CdTe for far red and near-infrared. The size of the particle determines the exact color of a given quantum dot. The polymer coating protects cells from cadmium toxicity but also facilitates the attachment of a variety of targeting molecules, including monoclonal antibodies directed to tumor-specific biomarkers. Because of their small size, quantum dots can function as cell- and even molecule-specific markers that will not interfere with the normal cellular functions.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A three-dimensional nanoparticle which is made of material that exhibits quantum effects.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>quantum dot</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 79.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gold atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 65.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>terbium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antineoplastic agent, which inhibits the synthesis of DNA.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>DNA synthesis inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anticancer drug that is pharmacologically inactive but when exposed to ultraviolet light or sunlight, it is converted to its pharmacologically active metabolite.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>photosensitizing agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound which functions as a topoisomerase-II inhibitor and an antineoplastic antibiotic.</ncicp:def-definition></ncicp:ComplexDefinition>
anticancer drug that inhibits protein activity related to DNA synthesis
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A qualitative measure of "solubility in water" which indicates the poor ability of the chemical substance to dissolve in water under specific conditions.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>insoluble in water</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Role played by a material entity when it is used for labeling another material entity.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>labeling role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A colloid, which is a semi-solid or jelly like material formed by the coagulation of a colloidal liquid.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanofiber which is composed of graphene layers arranged as stacked cones, cups or plates. Carbon nanofibers with graphene layers wrapped into perfect cylinders are called carbon nanotubes.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carbon nanofiber</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 75.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>rhenium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The process of directing a molecule or a particle to a specific location in a tumor.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tumor targeting</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanotube which consists of one or more graphite sheets (graphene) of hexagonal arrays of carbon rolled into seamless cylinders with capped ends.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carbon nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 32.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>germanium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 18.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>argon atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 10 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Group 10 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The hollow core region of a nanocage.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hollow core of nanocage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexTerm><ncicp:term-name>lead atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carbonyl group which is characteristic of a ketone wherein it is attached to two carbon atoms via covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>ketone group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 8.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An angiogenesis inhibitor that acts by blocking the action of endothelial integrins. An endothelial-specific integrin/survival signaling inhibitor binds to and blocks the activity of endothelial-specific integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>endothelial-specific integrin inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
nanoparticle response to internal stimulus
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to stimulus, which occurs in response to the internal stimulus acting on the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nanoparticle response to internal stimulus</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is loaded with paclitaxel.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>paclitaxel-loaded nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A three-dimensional nanoparticle with a hollow core and a porous wall or shell. It's structure resembles that of a hollow cage, that is similar to a fullerene type of nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>DNA binding agent that is able to covalently bind to DNA causing inter- or intra-stranded cross-linking of DNA. The cross-linking results in misreading of the DNA code and inhibition of DNA synthesis.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>DNA crosslinking agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecule component in dendrimer which repeats to form the branches of a dendrimer.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>dendrimer repeat unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 108.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hassium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 7.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nitrogen atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 2 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Group 2 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an amide group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>amide linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition, inhering in any material entity, whose structure or function can be altered by sound.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity that inheres in a molecular entity or group, and that describes the ability of the bearer to be ionized.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 9 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Group 9 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle whuch is basically composed of solidified lipid molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>solid lipid nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Anticancer drug, which is the role of a molecular entity, realized from the kind of biological target where the molecular entity is primarily intended or directed to act.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>anticancer drug based on target</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
[classification source]: E. Espinosa, P. Zamora, J. Feliu and M. G. Baron, Classification of anticancer drugs-a new system based on therapeutic targets, Cancer Treatment Reviews, 29: 515-523 (2003).
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Magnetic property exhibited by materials in presence of an external magnetic field and the magnetism is retained for a period even after the magnetic field is removed (magnetic moments of the adjacent atoms are aligned in the same direction at temperatures below the Curie temperature).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecule role in nanoparticle, which inheres in a molecular entity that has active end-directed functions/activities and is transported and delivered by the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>payload agent role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A three-dimensional nanoparticle which is spherical, porous or non-porous and its diameter is measured in nanometers.</ncicp:def-definition></ncicp:ComplexDefinition>
amidine linkage between primary amine and imidoester
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amidine linkage which occurs between a primary amine and an imidoester, through covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>amidine linkage between primary amine and imidoester</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition, inhering in any material entity, whose structure or function can be altered by a stimulus.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>sensitivity to stimulus</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A colloid in which both phases are liquids that are immiscible with each other.[source: WordNet 3.0]</ncicp:def-definition></ncicp:ComplexDefinition>
[source]: http://www.thefreedictionary.com
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imide is an amide which is characterized by the presence of an imide group. It has the structure R-C(=O)-N(-R')-C(=O)-R", where R, R" denote organic groups, and R' stands for organic group or hydrogen atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An independent continuant [snap:IndependentContinuant] consisting of a characteristic spatial shape in relation to some arrangement of material entities and of the medium which is enclosed in whole or in part by this characteristic spatial shape. Material site entities are entities that can be occupied by other material entities.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>material site</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
A foreign molecule could be covalently linked to a molecular constituent or it could occupy a void space / cavity by participating in non-covalent interactions iwth neighboring molecular constituents.
[previous definition]: An independent continuant which describes any distinguishable point, site or location in a material entity, and the location is either that of a group of molecular constituents in a material entity, or the space surrounded by the molecular constituents.
definition of material site is based on the definition of snap:Site
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A material site which is a cavity or space formed within the core and generation layer (between branches) of a dendrimer. It can be occupied by molecules other than those which chemically make up the dendrimer.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>dendrimer cavity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fluorescent dye which is used to stain a specimen or a sample in fluorescence microscopy.</ncicp:def-definition></ncicp:ComplexDefinition>
thioether linkage between thiol and iodoacetyl derivative
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thioether linkage which occurs between a thiol and an iodoacetyl derivative, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>thioether linkage between thiol and iodoacetyl derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A semisynthetic derivative of camptothecin, a cytotoxic, quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom of fluorine or chlorine or bromine or iodine or astatine.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>halogen atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an arylthioether group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>arylthioether linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A crosslinking agent which contains two different end reactive groups connected by a spacer, and the two reactive groups can couple to two different functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>heterobifunctional crosslinker</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound which is characterized by the presence of a succinimidyl carbonate group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>succinimidyl carbonate compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 88.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 90.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An internal stimulus for nanoparticle function, which is caused by a change in pH of the medium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>stimulus of pH change</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 99.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>einsteinium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An attractive non-covalent interaction between two or more (otherwise non-associated) molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>intermolecular interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element in the fifth row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Period 5 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 16.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>sufur atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A non-metal which is any of the following elements: argon, helium, krypton, neon, radon, xenon.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>noble gas</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a core part and a shell part, and both the core and shell are distinguished by their respective material content.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>core-shell nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
drug release from nanoparticle in response to magnetic field
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to magnetic field, which involves the release of drugs from a drug-loaded nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>drug release from nanoparticle in response to magnetic field</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 85.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 8 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Group 8 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as the simplest micro-electro-mechanical system (MEMS) that is easily machined and mass-produced for probing nanoscale specimens.</ncicp:def-definition></ncicp:ComplexDefinition>
Nanocantilevers are often used to explore and characterize the surfaces of biological systems. The motion of the device is recorded and transformed mathematically to provide information about these surface characteristics.
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A polyhedral shape that inheres in a 3-dimensional object having six plane faces.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>hexahedral shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has only one external dimension in the nanoscale size range.</ncicp:def-definition><ncicp:Definition_Review_Date>110104</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>one-dimensional nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 52.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality that inheres in a molecular entity which does not contain carbon as a principal element (some exceptions exist, e.g., carbon dioxide).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>A fluid state of matter having no fixed shape but a fixed volume.</ncicp:def-definition><ncicp:Definition_Review_Date>130524</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The exterior surface of a dendrimer formed by the dendrimer's end/surface groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>exterior surface of dendrimer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>An independent continuant [snap:IndependentContinuant] which is spatially extended and composed of matter. The identity of material entities is independent of that of other entities and can be maintained through time.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>material entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
Matter is any physical substance that has mass and occupies space.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 33.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element in the second row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Period 2 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by magnetic field.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>stimulus of magnetic field</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a coating agent composed of a biopolymer.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>biopolymer-coated nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 78.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 43.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>technetium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=O)-O- and it is formally derived from carboxylic acid and organic hydroxy compound. The group is characteristic of a carboxylic ester compound wherein it is attached to two carbon atoms via single covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carboxylic ester group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent bonding in which the sharing of electron pair is unequal due to difference in the electronegativities of atoms that share the electron pair.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>polar covalent bonding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as a probing tool of nanometer-size, and combined with a nanosensor, is useful for subcellular detection of activity or phenomenon (e.g. biological phenomenon or process).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>A molecule which is used for targeting other molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>targeting agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fullerene refers to any cagelike, hollow molecule composed of hexagonal and/or pentagonal groups of carbon atoms , and it is regarded as the third form of carbon after diamond and graphite.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -O-C(=O)-O-. The group is characteristic of a carbonate ester molecule wherein it is attached to two carbon atoms via single covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carbonate ester group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 83.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality which inheres in a group of multiple bearers AND specific only to the type of bearers in the group.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>specific collective quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 26.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>iron atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as a template consisting of two-dimensional patterning of biological molecules on a surface for biological analysis.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 3 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Group 3 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular component which is a functional group that is part of a dendrimer and it is located at the surface of a dendrimer.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>dendrimer end group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which is formally derived by the removal of one or more hydrogen atoms from ammonia, by virtue of which it has the structure -NH2 or -NH- or -N(-)-. The group is characteristic of an amine molecule wherein it is attached to hydrocarbyl groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>amine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 58.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle loaded with tamoxifen.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tamoxifen-loaded nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by sound.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>stimulus of sound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 12 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Group 12 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 95.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>americium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as an in vivo implantable device, designed to deliver drugs under zero order rate kinetics at high local drug concentrations to non-resectable tumor lesions.</ncicp:def-definition></ncicp:ComplexDefinition>
[definition source]: Lesinski et al, Biomedical Microdevices, vol 7, number 1, 71-79, 2005
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 20.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>calcium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A primary particle which has an average size in the nanoscale range; which has an identifiable and definite chemical composition, property or function that uniquely define the nanoparticle's type as known; and, which may or may not exhibit a size-intensive property.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
Definition is partly based on ASTM E 2456-06 (Terminology for Nanotechnology).
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 19.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 89.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>actinium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 15.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>phosphorus atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A nanostructured material which is formed by the combination of single-walled carbon nanotubes and fullerenes wherein the fullerenes are covalently bonded to the outer surface of the nanotubes.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
[definition source]: Nasibulin, A. G., Peter. V. Pikhitsa, Hua. Jiang, David. P. Brown, A. V. Krasheninnikov, Anton S. Anisimov, Paula Queipo, Anna Moisala, David Gonzalez, Gunther Lientschnig, Abdou Hassanien, Sergey D. Shandakov, Giulio Lolli, Daniel E. Resasco, Mansoo Choi, David Tománek, and Esko I. Kauppinen "A Novel Hybrid Carbon Nanomaterial". Nature Nanotechnology 2(3), 156-161 (2007).
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A crosslinker which has two identical reactive ends connected by a carbon chain spacer and are used mostly to crosslink molecules or parts of molecules in a one-step chemical crosslinking procedure.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>homobifunctional crosslinker</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of the periodic table of elements.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>periodic table element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
drug release from nanoparticle in response to ultrasound
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to ultrasound, which involves the release of drugs from a drug-loaded nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>drug release from nanoparticle in response to ultrasound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 90.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>thorium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
external stimulus for nanoparticle function
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A stimulus for nanoparticle function, which originates from a source that is outside of the the medium in which the nanoparticle is located.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>external stimulus for nanoparticle function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electron is in an s-orbital.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>s-block element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A supramolecular structure which is a closed vesicle that forms on hydration of dry phospholipids above its transition temperature.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure N#C-O-. The group is characteristic of a cyanate molecule wherein it is attached to an organic group via a single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cyanate group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A linear polysaccharide of deacetylated beta-1,4-D-glucosamine; deacetylated chitin.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 46.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>palladium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A three-dimensional nanoparticle which consists of a nuclear core surrounded by a lighter lipid membrane.</ncicp:def-definition></ncicp:ComplexDefinition>
Nanocell was first used for sequential delivery of anti-angiogenesis and chemotherapeutic agent to solid tumors.The chemotherapeutic agent can be conjugated to a nanoparticle in the core, while the anti-angiogenesis agent can be encapsulated in the lipid membrane.It was designed to first cause membrane disruption for release of anti-angiogenesis agent, which causes tumor vascular collapse, and finally cause intra-tumoral trapping of the core chemotherapeutic drug-conjugated nanoparticles.
[definition source]: Sengupta et al, Nature Letters, vol 436, 2005
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A three-dimensional nanoparticle which consists of a shell and a space, in which desired substances may be placed. It can be cylindrical or spherical in shape.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -E(=N-)-NH2, where E could denote carbon (C) or (Sulfur). The group is characteristic of an amidine compound.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>amidine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 43.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 93.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality which inheres in a group of multiple bearers AND NOT specific only to the type of bearers in the group.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>general collective quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which is basically composed of iron oxide.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>iron oxide nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Buckyball (C60) or Buckministerfullerene, is a type of fullerene which comprises of 60 carbon atoms arranged in interlocking hexagons and pentagons, like the patches on a soccer ball. Its geometry is roughly spherical and it has a hollow interior.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by heat.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>stimulus of heat</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable property which inheres in a molecule that has both hydrophobic and hydrophilic parts.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>A pure substance which is made up of one type of atom, and it cannot be decomposed or transformed by a chemical reaction into a different substance, although it can be transmutated into an isotope through a nuclear reaction.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polymeric molecule which has a highly-branched, three-dimensional tree-like architecture, synthesized from monomers where shells of branched molecules are added in discrete steps to a central core.</ncicp:def-definition></ncicp:ComplexDefinition>
[MeSH definition]: Tree-like, highly branched, polymeric compounds. They grow three-dimensionally by the addition of shells of branched molecules to a central core. The overall globular shape and presence of cavities gives potential as drug carriers and CONTRAST AGENTS.
[NCI_THESAURUS definition]: A polymeric molecule which has a highly-branched, three-dimensional architecture. Dendrimers are synthesized from monomers and new branches are added in discrete steps to form a tree-like architecture. A high level of synthetic control is achieved through step-wise reactions and purification at each step to regulate the size, architecture, functionality and monodispersity of the molecules. These polymers have desirable pharmacokinetic properties and a polyvalent array of surface groups that make them potential drug delivery vesicles.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 47.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antineoplastic agent isolated naturally from microorganisms or synthesized chemically that kills or inhibits the growth of tumor cells. Antineoplastic antibiotics can interfere with the normal function of cellular nucleic acids and proteins.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>antineoplastic antibiotic</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
amide linkage between primary amine and carboxylic ester
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide linkage which is formed between a primary amine and a carboxylic ester.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>amide linkage between primary amine and carboxylic ester</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 39.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acyl halide group in which the halogen atom is a "bromine atom."</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>acyl bromide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 50.</ncicp:def-definition></ncicp:ComplexDefinition>
instantaneous dipole-induced dipole interaction
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dipole-dipole interaction between non-polar molecules due to attraction between an instantaneous dipole on one non-polar molecule and an induced dipole on the other non-polar molecule; the temporary dipole on the latter molecule is induced by the randomly occurring (temporary) instantaneous dipole of the former molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>instantaneous dipole-induced dipole interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
induced dipole-induced dipole interaction
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 11 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Group 11 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a carboxylic ester group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carboxylic ester linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 54.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide group which has the structure -S(=O)-NH2 or -S(=O)-NH- or -S(=O)-N(-)-. The group is characteristic of a sulfonamide wherein it is attached to organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>sulfonamide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a diazo group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>diazo linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process which describes an action or event that triggers a specific function of a nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>stimulus for nanoparticle function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
internal stimulus for nanoparticle function
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A stimulus for nanoparticle function, which originates from a source that is inside the medium in which the nanoparticle is located.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>internal stimulus for nanoparticle function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 64.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gadolinium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 76.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with properties between a metal and a non-metal.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to external stimulus, which occurs in response to infrared light.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nanoparticle response to infrared light</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 58.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cerium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A halo group in which the halogen atom is a chlorine atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>chloro group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A thin layer of nanostructured material.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A fiat material part which is a material layer surrounding the core.</ncicp:def-definition><ncicp:Definition_Review_Date>100624</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 48.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cadmium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanotube which consists of one or more sheets of hexagonal arrays of silicon rolled into seamless cylinders with capped ends.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>silicon nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity inhering in particles (e.g, nanoparticles), which gives the bearer the ability to disperse in an aqueous medium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule, in which carbon is the principal element.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>organic compound or molecule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 40.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An intermolecular interaction between an ion and a polar molecule by virtue of an attraction between the ionic charge and a permanent dipole on the polar molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>charge-dipole interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
the polar molecule has permanent molecular dipole moment.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by ultraviolet light.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>stimulus of ultraviolet light</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A material site which is a nanoscale cavity or channel confined within a membrane or solid matter.</ncicp:def-definition></ncicp:ComplexDefinition>
[NCI_Thesaurus definition]: A nanoscale cavity or channel confined within a membrane or solid matter.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 47.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>silver atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A colloidal gel in which water is the dispersion medium.[source: WordNet 2008]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 42.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>molybdenum atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 61.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 65.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular structure which is a branch of a dendrimer, formed by the dendrimer's repeating units.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>dendrimer branch</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process or mechanism which inhibits tumor angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tumor angiogenesis inhibition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanodevice which has the end-directed activity/function to serve as a sensor/detector of any activity, phenomenon or molecule, within a nanometer-range resolution; it responds to a stimulus by sending a signal that can be measured.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 89.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 3.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Topoisomerase inhibitor which either stabilizes DNA-protein complexes damaging DNA (e g., teniposide), or inhibits the catalytic activity of the topoisomerase (e.g., merbarone).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>topoisomerase-II inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A fluid having neither independent shape nor volume and being able to expand indefinitely.[source:NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality that inheres in a molecule or chemical bond due to the absence of dipole moments.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 21.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>scandium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aminoacid which is aromatic in nature.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>aromatic aminoacid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The outer surface of a nanotube to which other molecular entities can be attached. (For example, attachment of fullerene on the surface of carbon nanotube.)</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>outer surface of nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cross-linking agent for mediating the conjugation of two molecules by forming a bond between functional groups of the molecule while containing no additional atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>zero-length crosslinker</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 27.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 16.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thioether is an organic compound which is characterized by the presence of a thioether group. It has the structure R-S-R', where R, R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 74.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a coating agent composed of polyethylene glycol.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>PEGylated nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
poly(ethylene) glycol-coated nanoparticle
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality that inheres in a molecular entity which contains carbon as a principal element.</ncicp:def-definition></ncicp:ComplexDefinition>
definition for organic is based on the CHEBI definition for organic compounds (CHEBI:25700)
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecule component in dendrimer which forms the core of a dendrimer.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>dendrimer core molecule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 28.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 69.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>thulium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
amide linkage between primary amine and carboxylic acid
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide linkage which is formed between a primary amine and a carboxylic acid.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>amide linkage between primary amine and carboxylic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 33.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>arsenic atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 104.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 22.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>titanium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An internal stimulus for nanoparticle function, which is caused by a change in temperature.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>stimulus of temperature change</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 35.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>bromine atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 52.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tellurium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A chemical substance which deforms under an applied stress, and conforms to the outline of its container.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 44.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 30.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 110.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>darmstadtium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a collection of objects based on size or molecular weights (e.g., particles, polymers).</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide group which has the structure -P(=O)-NH2 or -P(=O)-NH- or -P(=O)-N(-)-. The group is characteristic of a phosphoramide wherein it is attached to organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>phosphoramide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antibody produced by a clone or genetically homogenous fast-growing cells i.e., hybridoma. Hybridoma cells are cloned to establish cell lines producing a specific antibody that is chemically and immunologically homogeneous.[source: NCI_Thesaurus]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>monoclonal antibody</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A amide group which has the structure -C(=O)-NH2 or -C(=O)-NH- or -C(=O)-N(-)-. The group is characteristic of a carboxamide wherein it is attached to organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carboxamide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A halo group in which the halogen atom is a fluorine atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>fluoro group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical component in a nanoparticle formulation, which is there to modify the nanoparticle's surface properties like surface charge or surface hydrophilicity; or 2) to which other molecular entities can be attached for facilitating linkage between the molecular entities and the nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nanoparticle surface modifying agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A supramolecular structure which is an aggregate of amphiphilic molecules in a polar solvent.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Role played by a material entity that serves as the target for a targeting agent in a targeting process.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>target role</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group derived by the removal of a hydrogen atom from a carboxylic acid, by virtue of which it has structure -C(=O)-[O-]. The group is characteristic of a carboxylate compound wherein it is attached to the remaining part of the molecule via a covalent bond between the oxygen atom and a carbon atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carboxylate group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The porous shell of a nanocage.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>porous shell of nanocage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A substance which has an ordered 3-dimensional structure due to the closely packed arrangement of constituting atoms, molecules or ions. As a result, the substance has a definite shape and volume, and the shape can be modified under application of a force.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A colloid that has a continuous liquid phase in which a solid is suspended in a liquid.[source: WordNet 2008]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a biodegradable property.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>biodegradable nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
enhanced permeability and retention effect
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A passive targeting process, which results in the accumulation of particulate substances in angiogenic tumors due to enhanced permeability of particles across leaky tumor endothelium and retention of the particles inside the tumor due to its defective lymphatic drainage system.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>enhanced permeability and retention effect</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
[definition source]: Y. Matsumur and H. Maeda, A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent Smancs, Cancer Research, 46, 6387-6392 (1986).
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 18.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 95.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where an arylamine group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>arylamine linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An isothiocyanate is an organic compound which is characterized by the presence of an isothiocyanate group. It has the structure R-N=C=S, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of the periodic table for which, in the atomic ground state, the highest-energy electrons occupy p-orbitals.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>p-block element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A glucan which is a high-molecular-weight polymer of d-glucose, produced by enzymes on the cell surface of certain lactic acid bacteria.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 94.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A peptide which consists of several aminoacids .</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element in the seventh row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Period 7 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shape formed by a closed, curve whose path is traced by a point moving in a plane such that the sum of its respective distances from two fixed points (the ellipse's foci) is constant.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>elliptical shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 100.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A rod shape inhering in a long and slender rod, which resembles a needle.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>needle shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A gas that is a solid or liquid at normal room temperature. [source:NCI]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aminoacid which is aliphatic in nature.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>aliphatic aminoacid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 97.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>berkelium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 6.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A shape inhering in a 3-dimensional object that resembles a solid figure bounded by plane polyons or faces.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>polyhedral shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Magnetic property -similar to paramagnetism - which is exhibited in materials when the temperature of the material is below the Curie temperature.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A regular hexahedral shape that inheres in a 3-dimensional object having six equal squares as faces.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>cubical shape</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 54.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>xenon atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 67.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>holmium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Topoisomerase inhibitor which inhibits the action of topoisomerase I.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>topoisomerase-I inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 29.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>copper atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acryloyl compound is an "organic compound" which is characterized by the presence of an "acryloyl group". It has the structure R-C(=O)-CH=CH2, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>acryloyl compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A qualitative measure of polydispersity, inhering in a collection of particles that are of different sizes or of polymers that have varying molecular weights.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>A nanomaterial which is a particulate chemical substance that is formulated systematically using nanotechnology, and it contains nanoparticles and active chemical components/ingredients.</ncicp:def-definition><ncicp:Definition_Review_Date>110825</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nanoparticle formulation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
Nanotechnology involves the application of scientific knowledge from multidisciplinary fields of science and engineering, towards understanding, manipulating and controlling the properties of matter at the nanoscale (1-100 nm) size dimensions.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 4.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>beryllium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanohorn that is comprised of a single layer of graphitic carbon and exhibits an irregular horn-like shape. One of the primary characteristics of carbon nanohorns is their ability to aggregate. This aggregation is advantageous because of the resulting enhanced permeability in both gases and liquids.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>single-walled nanohorn</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element in the fourth row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Period 4 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 98.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>californium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antineoplastic agent, which prevents or impairs tumor metastasis.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>antimetastatic agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An L-phenylalanine nitrogen mustard.</ncicp:def-definition></ncicp:ComplexDefinition>
anticancer drug that induces breakage of DNA helix
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Enzyme inhibitor that inhibits dihydrofolate reductase by interfering with the conversion of Dihydrofolate to Tetrahydrofolate, causing inhibition of nucleotide biosynthesis and protein synthesis.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>dihydrofolate reductase inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 6.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carbon atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by visible light.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>stimulus of visible light</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 42.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Core part of a micelle formed by hydrophobic (non-polar) tails of individual amphiphilic molecules that form the whole micelle in a polar solvent, which has void spaces to include other hydrophobic molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hydrophobic core of micelle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 106.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>seaborgium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An dipole-dipole interaction between two polar molecules due to attraction between their permanent dipoles.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>permanent dipole-dipole interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disulfide linkage which is formed between two thiol compounds, through covalent interactions between atoms of respective sulfhydryl groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>disulfide linkage between two thiols</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality, which is the physical condition of a material entity, based on its chemical composition and structure.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>physical state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amine group which is formally derived by the removal of two hydrogen atoms from ammonia, by virtue of which it has the structure -NH-. The group is characteristic of a secondary amine molecule wherein it is attached to hydrocarbyl groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>secondary amine group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
amide linkage between primary amine and acyl azide
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide linkage which is formed between a primary amine and an acyl azide.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>amide linkage between primary amine and acyl azide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A qualitative measure of polydispersity, inhering in a collection of particles that are of the same size or of polymers that have uniform distribution of molecular weights.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>A two-dimensional nano-object which is an elongated fiber of diameter less than 100 nm.</ncicp:def-definition><ncicp:Definition_Review_Date>101208</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=O)-O-C(=O)-. The group is characteristic of acid anhydrides.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>acid anhydride group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
The structure of an acid anhydride is R-C(=O)-O-C(=O)-R', in which two acyl groups are bonded to the same oxygen atom; and , R,R' denote hydrogen atoms or organic groups.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A solid which is formed by the solidification of a chemical and having a highly regular atomic structure.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 56.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>barium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound in which a halogen atom is bonded to a carbon atom that is part of an aromatic ring. It is characterized by the presence of aryl halide groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>aryl halide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A biological process having an abnormal or deleterious effect at the subcellular, cellular, multicellular, or organismal level. (NCI)</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>pathologic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 2.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The process in which material entities (e.g., nanoparticles) are targeted to tumor sites, cancer cells or intracellular organelles in cancer cells, with the help of molecular agents (conjugated to the material entities) that recognize and bind to specific biological molecules at the target location.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>active targeting</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Receptor mediated endocytosis, which is the process by which cells internalize folate molecules that specifically bind to folate receptors.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>folate receptor mediated endocytosis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A nanoparticle which has all three external dimensions in the nanoscale size range.</ncicp:def-definition><ncicp:Definition_Review_Date>101223</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>three-dimensional nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 11.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has a three-membered cyclic ether structure, where an oxygen atom is attached to two carbon atoms and the carbon atoms are bonded to each other via single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>epoxide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element in the sixth row (or period) of the periodic table of the elements.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Period 6 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process which inhibits or blocks the induction, promotion, maintenance, or completion of cell division in cancer cells.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>inhibition of cancer cell growth</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A solid which corresponds to tiny loose particles, produced by pulverization.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A liposome vesicle that has a single lipid bilayer.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>unilamellar vesicle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug directed to interfere with the activity of a membrane protein receptor of the tumor cell.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>drug directed against membrane receptor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A contrast agent, which provides contrast in images captured using acoustic imaging techniques.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>acoustic imaging contrast agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An activity, which involves the killing of tumor cells; or which causes reduction of tumor size.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>antitumor activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic antimetabolite which affects the metabolism and utilization of purines.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>purine antagonist</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process by which cells internalize molecules by the inward budding of plasma membrane vesicles containing proteins with receptor sites specific to the molecules being internalized.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>receptor mediated endocytosis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A reagent containing ends reactive to specific functional groups on molecules for modifying and linking molecules together.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>crosslinking reagent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 22.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A solid which corresponds to any small grainlike particle.</ncicp:def-definition></ncicp:ComplexDefinition>
heat generation in response to stimulus of infrared light
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to infrared light, which involves the generation of heat.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>heat generation in response to stimulus of infrared light</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acyl azide is an acyl compound which is characterized by the presence of acyl azide group. It has the structure R-C(=O)-[N+]#N, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>acyl azide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 68.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 21.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 70.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 36.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 24.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>chromium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 27.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cobalt atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 57.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An external stimulus for nanoparticle function, which is caused by infrared light.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>stimulus of infrared light</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity that inheres in a material entity and indicates that the bearer has the ability to be harmless to biological systems.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Antineoplastic agent that binds to DNA to regulate mechanisms central to cellular function, including DNA replication and gene expression.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>DNA binding agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chemical interaction which is non-covalent in nature and provides the force to hold molecules or parts of molecules together.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>non-covalent interaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 102.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A single-walled nanotube which consists of a single graphite layer or sheet of hexagonal arrays of carbon, rolled into a seamless cylinder with a diameter close to 1 nanometer.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>single-walled carbon nanotube</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure R-C(=O)-X, where R denotes an organic group and X, a halogen atom. The group is characteristic of an acyl halide.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>acyl halide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
Prefix: haloformyl- ; Suffix: -oyl halide
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A physiologically-dependent process by which a material entity reaches tumor sites, cancer cells or intracellular organelles in cancer cells.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>passive targeting</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 91.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>protactinium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 34.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle which has a coating agent composed of dextran.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>dextran-coated nanoparticle</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic quality inhering in a chemical substance due to the presence of cyclic or acyclic, saturated or unsaturated carbon compounds, but with the exclusion of aromatic quality.</ncicp:def-definition></ncicp:ComplexDefinition>
Definition of aliphatic is based on the CHEBI definition for aliphatic compounds (CHEBI:33653)
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality that inheres in a molecule or chemical bond due to the presence or absence of dipole moments.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 92.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ionizable property inhering in a chemical substance by virtue of having the ability to be ionized and gain a negative charge.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>ionizable to gain negative charge</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 81.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>thalium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An epoxide compound is an organic compound which is characterized by the presence of an epoxide group. It has the structure R-C1H-CH2-O1, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>epoxide compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An internal stimulus for nanoparticle function, which is caused by a change in pO2.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>stimulus of pO2 change</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 102.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nobelium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Drug directed against the DNA in a tumor cell to inhibit DNA replication.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>anticancer drug that induces breakage of DNA helix</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent bonding in which the sharing of electron pair is equal.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>non-polar covalent bonding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
occurs for covalent bond between similar types of atoms or between atoms that have almost zero electronegativity difference.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A spacer, which can be cleaved in response to a change in pH of the solution containing that spacer.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>pH-sensitive linker</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dendrimer which contains amide molecules as branches; tertiary amines as branching points and primary amine groups as the terminal or end groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>poly(amidoamine) dendrimer</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 94.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>plutonium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 68.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>erbium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 8.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>oxygen atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group derived by replacing the =O of an aldehyde or a ketone group with =N-NH2 or =N-NH-R'. It has the structure -C(=N-NH2)- or -C(=N-NH-)-, and the group is characteristic of a hydrazone.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hydrazone group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 96.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 69.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A material entity which is one of two or more forms of atoms - of a chemical element-that contain the same number of protons but different number of neutrons in their nuclei. Hence an isotope differs from an atom in relative atomic mass and physical properties but not in chemical properties; an isotope is a radioactive form of element.</ncicp:def-definition><ncicp:Definition_Review_Date>100623</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
drug release from nanoparticle in response to pH change
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nanoparticle response to pH change, which involves the release of drugs from a drug-loaded nanoparticle.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>drug release from nanoparticle in response to pH change</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 48.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 12.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>magnesium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 63.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>europium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element of Group 7 of the periodic table.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Group 7 Element</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atom with atomic number 104.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>rutherfordium atom</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 71.</ncicp:def-definition></ncicp:ComplexDefinition>
amine-reactive and sulfhydryl-reactive crosslinker
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A heterobifunctional crosslinker, which has an amine-reactive group at one end and a sulfhydryl-reactive group at the other end.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>amine-reactive and sulfhydryl-reactive crosslinker</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition inhering in any material entity, whose structure or function can be altered by changes in temperature.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which contains a carboxylic ester bound to a primary or secondary or tertiary amine group. The group is characteristic of a carbamate ester compound.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carbamate ester group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A covalent linkage where a disulfide group is formed due to covalent bonding between atoms of chemical groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>disulfide linkage</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
thioether linkage between thiol and aziridine derivative
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thioether linkage which occurs between a thiol and an aziridine derivative, through the covalent interactions between atoms of respective functional groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>thioether linkage between thiol and aziridine derivative</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 35.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acyl halide group in which the halogen atom is an iodine atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>acyl iodide group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An element with atomic number 72.</ncicp:def-definition></ncicp:ComplexDefinition>
This is in support of NCI Edit tab Merge and PreMerge function
This is in support of the NCI Edit Tab Retired and Preretire functions
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-SH)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxygen hydride which is a liquid and has the chemical formula H2O</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH2-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion of bromine.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A biopolymer composed of nucleotide monomers which are covalently bonded in a long chain.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion of halogen element.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>halide anion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion of iodine.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-CH2-S-CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion of fluorine.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A ketone is a carbonyl compound wherein the carbonyl group is bonded to two carbon atoms. It is characterized by the presence of a ketone group, and therefore, has the structure R-C(=O)-R', where R,R' stand for organic groups and not hydrogen atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phosphoramide is an amide characterized by the presence of a phosphoramide group. It has the structure R-P(=O)-NH2, R-P(=O)-NH-R' or R-P(=O)-N(-R")-R', where R,R',R" denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aldehyde is a carbonyl compound wherein the carbonyl group is bonded to one hydrogen atom, and one organic group or another hydrogen atom. It is characterized by the presence of an aldehyde group, and has the structure R-C(=O)H, where R denotes an organic group or a hydrogen atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound which has the formula (OH)CH2-C(OH)=O.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>glycolic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-OH)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion of chlorine.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A biopolymer which consists of large numbers of monosaccharide residues linked glycosidically.</ncicp:def-definition></ncicp:ComplexDefinition>
This term is commonly used only for those polysaccharides that contain more than ten monosaccharide residues.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(Cc1ccc(O)cc1)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2CH2C(OH)=O)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>glutamic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic dication of magnesium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>magnesium (2+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which is derived by the removal of one or more hydroxyl groups from an oxoacid. It has the structure R-C(=O)-, where R denotes an organic substituent from the oxoacid.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>acyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrocarbyl group which is derived from an alkane by removal of a hydrogen atom from any carbon atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>alkyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
Alkyl group is a substituent group from alkane.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ion which is negatively charged.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of arsenic.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>arsenic molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2CH(NH)=O)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2CH(OH)=O)-C(OH)=OH</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>aspartic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A glycopeptide, which is isolated from fungus; and with iron, it forms complexes that reduce molecular oxygen to superoxide.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of boron.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>boron molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of bromine.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>bromine molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of cadmium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cadmium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carbamate ester is an organic compound which is characterized by the presence of a carbamate ester group. It has the structure R-O-C(=O)-NH2 or R-O-C(=O)-NH-R' or R-O-C(=O)-N(-R")-R', where R, R', R" denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carbamate ester</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The generic term 'carbohydrate' includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more terminal groups to carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom, an amino group, a thiol group or similar heteroatomic groups. It also includes derivatives of these compounds. The term 'sugar' is frequently applied to monosaccharides and lower oligosaccharides. Cyclitols are generally not regarded as carbohydrates.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=O)-. The group is characteristic of a carbonyl compound wherein it is attached to the remaining part of the molecule via single covalent bonds.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carbonyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of chlorine.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>chlorine molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of chromium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>chromium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A molecular entity is any molecule, ion, ion pair, radical ion, complex, conformer,etc., identifiable as a separately distinguishable entity.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of copper.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>copper molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A terpenoid which has a C20 skeleton.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion which consists of a single atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>monoatomic anion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cation which consists of a single atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>monoatomic cation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of fluorine.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>fluorine molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A peptide compound in which a carbohydrate component is linked to a peptide component.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a molecular entity or part thereof, by virtue of its chemical composition and/or connectivity between its constituent atoms; or a complex composition of other molecular entities.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>molecular structure</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A group is a defined linked collection of atoms or a single atom within a molecular entity.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a halogen (Group-17) element.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>halogen molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cyclic organic compound, which has ring members that are atoms of carbon and at least of one other element such as sulfur, oxygen or nitrogen.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>organic heterocyclic compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A compound which contains a hydroxy group or salts containing hydroxide (OH(-)).</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An imine is an organic compound which is characterized by the presence of a carbon-nitrogen double bond, and has the structure R-C(=N-R")-R', where at least one of R,R',R" is a hydrocarbyl group while the remaining being hydrogen atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion which is inorganic.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>inorganic anion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains no carbon.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>inorganic molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of iodine.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>iodine molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A chemical compound which is formed by ionic interactions between cations and anions.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ion which consists of a single atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>monoatomic ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A chemical entity which carries a net electric charge.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of iron.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>iron molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH(CH3)-CH2-CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any lipid which is formally derived from isoprene (2-methylbuta-1,3-diene), the skeleton of which can generally be discerned in repeated occurrence in the molecule. The skeleton of isoprenoids may differ from strict additivity of isoprene units by loss or shift of a fragment, commonly a methyl group. The class includes both hydrocarbons and oxygenated derivatives.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-CH(CH3)-CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-CH2-CH2-CH2-NH2)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of manganese.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>manganese molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of mercury.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>mercury molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic cation of a metal.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>metal cation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quinone which is an aziridine-containing compound isolated from Streptomyces lavendulae.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>A molecule which consists of atoms of the same element.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>homoatomic molecule</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of molybdenum.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>molybdenum molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic cation which has ionic charge 1+.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>monoatomic monocation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic cation which has ionic charge greater than 2+.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>monoatomic polycation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A compound in which monosaccharide units are joined by glycosidic linkages. The term is commonly used to refer to a defined structure as opposed to a polymer of unspecified length or a homologous mixture. When the linkages are of other types the compounds are regarded as oligosaccharide analogues.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion which is organic.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>organic anion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cation which is organic.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>organic cation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ether is an organic compound in which an oxygen atom is covalently bound to two carbon atoms. It has the structure R-O-R', where R, R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ion which is organic.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>organic ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A chemical compound of oxygen with other chemical elements.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of oxygen.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>oxygen molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of phosphorus.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>phosphorus molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A ketone which is a natural compound containing alternating carbonyl and methylene groups ('?-polyketones'), biogenetically derived from repeated condensation of acetyl coenzyme A (via malonyl coenzyme A); or another compound derived from it by further condensations.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amidine is an organic compound which is derived from an oxoacid RnE(=O)OH by replacing the hydroxyl group by an amino group and the oxo group by =NR. R stands for a hydrogen atom or organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic heterobicyclic compound which is composed partly or wholly of a pteridine ring system (a pyrimidine ring fused with a pyrazine ring).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>pteridine compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A pterin compound which is wholly composed of a pteridine ring system, in which the pyrimidine ring has a carbonyl oxygen and an amino group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A pteridine compound which is wholly or partly composed of a pteridine ring system in which the pyrimidine ring has a carbonyl oxygen and an amino group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>pterin compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of selenium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>selenium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of silicon.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>silicon molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of sulfur.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>sulfur molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of technetium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>technetium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any natural product and related compound formally derived from isoprene units. They may contain oxygen in various functional groups. This class is subdivided according to the number of carbon atoms in the same manner as are terpenes. The skeleton of terpenoids may differ from strict additivity of isoprene units by the loss or shift of a fragment, generally a methyl group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic polycation which has ionic charge 4+.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>monoatomic tetracation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH(OH)-CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of tin.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tin molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic polycation which has ionic charge 3+.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>monoatomic trication</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic heterocyclic compound, which has two rings.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>organic heterobicyclic compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2(CH3)-CH3)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of vanadium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>vanadium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of zinc.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>zinc molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A pterin compound which contains para-aminobenzoic acid and L-glutamate unit conjugated with the pterin structure.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>folic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
2-amino-3-(1H-imidazol-4-yl)propanoic acid
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2c1c[nH]cn1)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A pteridine compound in which a pyrimidine ring is fused with a pyrazine ring. It has the structure c1cnc2ncncc2n1.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(Cc1c[nH]c2ccccc12)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A platinum compound in which the platinum atom is complexed with two ammonia groups and two chlorine atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-c1ccccc1)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2CH2C(NH2)=O)-C(OH)=OH.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound which has the formula CH3CH(OH)C(OH)=O.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>lactic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anthracycline which is (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-?-L-lyxo-hexopyranoside. It has a parent hydride, tetracene, and has substructures that classify it as a deoxy hexoside, and a quinone.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of nitrogen mustard and an organochlorine compound.</ncicp:def-definition></ncicp:ComplexDefinition>
2-amino-5-(carbamimidamido)pentanoic acid
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alpha-aminoacid with chemical formula NH2-CH(CH2-CH2-CH2-NH-C(NH2)=NH)-C(OH)=OH</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic dication of iron.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>iron (2+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic trication of iron.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>iron (3+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic dication of zinc.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>zinc (2+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thiol is an organic compound which is characterized by the presence of a sulfhydryl group. It has the structure R-SH, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -S-S-. The group is characteristic of an organic disulfide molecule wherein it is attached to organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>disulfanedyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -SH. The group is characteristic of a thiol molecule wherein it is attached to an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>sulfhydryl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
It is a substituent group from hydrogen sulfide.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which is a substituent group from diazene, and has the structure =[N+]=[N-]. The group is characteristic of a diazo compound wherein it is attached to an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>diazo group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic cation which has ionic charge 2+.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>monoatomic dication</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion of astatine.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic pentacation of molybdenum.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>molybdenum (5+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of silicon in which a silicon atom covalently bonded (double bond) with two oxygen atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>silicon dioxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic tetracation of silicon.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>silicon (4+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An alcohol is an organic hydroxy compound in which a hydroxyl group is attached to a saturated carbon atom. It has the general structure OH-C-([*])([*])[*].</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A platinum compound in which the platinum atom is complexed with two ammonia groups and a cyclobutane-dicarboxyl residue.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A platinum compound in which the platinum atom is complexed with 1,2-diaminocyclohexane (DACH) and with an oxalate bidentate ligand.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A secondary amine is an amine which is formally derived from ammonia by replacing two hydrogen atoms by hydrocarbyl groups, and it is characterized by the presence of a secondary amine group. It has the structure R-NH-R', where R,R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>secondary amine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A tertiary amine is an amine which is formally derived from ammonia by replacing three hydrogen atoms by hydrocarbyl groups, and it is characterized by the presence of a tertiary amine group. It has the structure R-N(-R")-R', where R,R' and R" denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tertiary amine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A primary amine is an amine which is formally derived from ammonia by replacing one hydrogen atom by a hydrocarbyl group, and it is characterized by the presence of a primary amine group. It has the structure R-NH2, where R denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>primary amine</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amine is an organic compound which is formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups, and it is thus characterized by the presence of a primary or secondary or tertiary amine groups. It has the structure R-NH2 or R-NH-R' or R-N(-R")-R', where R, R' and R" denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amide is an organic compound formally derived from an oxoacid by replacing an acidic hydroxyl group of the oxoacid by an amino or substituted amino group. It is characterized by the presence of an "amide group."</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic pentacation of vanadium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>vanadium 5(+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which consists of a single atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>monoatomic entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A compound which consists of a central atom (usually metallic) to which is attached a surrounding array of other groups of atoms.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>coordination compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound or molecule which is characterized by the presence of a functional group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>organic functional class</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any substituent group which does not contain carbon.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>inorganic group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrocarbyl group is a univalent substituent group formed by removing a hydrogen atom from a hydrocarbon.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hydrocarbyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A polyatomic entity which consists of a single element.</ncicp:def-definition><ncicp:Definition_Review_Date>111020</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>homoatomic molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anion which consists of more than one atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>polyatomic anion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A heteroorganic compound is an organic compound in which carbon atoms or organic groups are bonded directly to one or more heteroatoms.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>heteroorganic compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of an alkali metal.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>alkali metal molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of an alkaline earth metal.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>alkaline earth molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a Group-15 element.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>pnictogen molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a Group-16 element.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>chalogen molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of tellurium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tellurium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carboxylic ester is an organic compound which is characterized by the presence of an carboxylic ester group. It has the structure R-C(=O)-O-R', where R,R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carboxylic ester</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An oxide of silicon.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>silicon oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrocarbyl group which is derived from an arene by removal of a hydrogen atom from a ring carbon atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>aryl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic polycation which has ionic charge 5+.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>monoatomic pentacation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic polycation which has ionic charge 6+.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>monoatomic hexacation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic anion which has ionic charge 1-.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>monoatomic monoanion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic monanion of rubidide.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic cation of alkali metal.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>alkali metal cation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monatomic cation of an alkaline earth metal.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>alkaline earth metal cation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carboxylic acid is an organic acid compound which is characterized by the presence of a carboxyl group. It has the structure R-C(=O)-OH, where R denotes an organic group or a hydrogen atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carboxylic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a Group-13 element.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>boron group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a Group-14 element.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carbon group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a noble gas.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>noble gas molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of germanium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>germanium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of lead.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>lead molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of aluminum.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>aluminum molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a zinc group (Group-12) element.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>zinc group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a s-block element.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>s-block molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a p-block element.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>p-block molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a d-block element.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>d-block molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A compound of hydrogen with other chemical elements.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydride containing one or more oxygen atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>oxygen hydride</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polymer formed by living organisms.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polynucleotide which is present in living cells.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nucleic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A nucleic acid which is a derivative of DNA having ribose in place of deoxyribose, and uracil in place of thymine.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>ribonucleic acid</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cation which consists of more than one atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>polyatomic cation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An aminoacid in which a primary amine group and a carboxyl group are attached to the same carbon atom, which is called the alpha?carbon..</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carboxylic acid containing one or more amine groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a chromium group (Group-6) element.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>chromium group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of tungsten.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tungsten molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a manganese group (Group-7) element.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>manganese group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a iron group (Group-8) element.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>iron group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a copper group (Group-11) element.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>copper group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a vanadium group (Group-5) element.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>vanadium group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a nickel group (Group-10) element.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nickel group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of nickel.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nickel molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of platinum.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>platinum molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a cobalt group (Group-9) element.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cobalt group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of a titanium group (Group-4) element.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>titanium group molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound which is characterized by the presence of one or more hydroxyl groups attached to carbon atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>organic hydroxy compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polymer is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A coordination compound which contains platinum as the central atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>platinum coordination compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of rhodium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>rhodium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of cobalt.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cobalt molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of silver.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>silver molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of gold.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gold molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organonitrogen compound is a heteroorganic compound containing at least one carbon-nitrogen bond.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>organonitrogen compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A sulfonamide is an amide derived from sulfonic acids, and thus characterized by the presence of a sulfonamide group. It has the structure R-S(=O)-NH2, R-S(=O)-NH-R' or R-S(=O)-N(-R")-R', where R,R',R" denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An amidine is an organic compound which is a derivative of a carboxylic acid, in which the hydroxy group is replaced by an amino group and the oxo group is replaced by =NR, and therefore, it has the structure R'-C(=N-R)-NH2, where R' denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrazide is an organic compound or molecule which is derived from an oxoacid RkE(=O)l(OH)m (l ? 0) by replacing ?OH by ?N(-R)-N(-R')-R" (R,R',R" groups commonly denote H).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carbohydrazide is a hyrazide derived from a carboxylic acid, and therefore has the structure R""-(C=O)-N(-R)-N(-R')-R", where R"" denotes an organic group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic disulfide is an organic compound which is characterized by the presence of a disulfanedyl group / disulfide bond. It has the structure R-S-S-R', where R,R' denote organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>organic disulfide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Anticancer drug, which brings about a cancer therapeutic effect by inhibiting or preventing the proliferation of neoplasms; i.e., it inhibits the maturation ,growth or spread of tumor cells.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>antineoplastic agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of ruthenium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>ruthenium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A biopolymer which is genetically encoded, the structure of which essentially consists of long chains of amino acid residues (derived from alpha aminoacids) connected by peptide bonds and have distinct and varied three-dimensional structures, usually containing alpha helices and beta sheets as well as looping and folded chains.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Cyclic ketone having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of ?CH= groups into ?C(=O)? groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which consists of more than one atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>polyatomic entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ion which consists of more than one atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>polyatomic ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carbonyl compound is an organic compound which is characterized by the presence of a carbonyl group, and therefore, has the structure R-(C=O)-R', where R, R" are organic groups or hydrogen atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carbonyl compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An acid anhydride is an organic compound which is characterized by the presence of an acid anhydride group. It has the structure R-C(=O)-O-C(=O)-R', where R, R' stand for organic groups or hydrogen atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>acid anhydride</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organochlorine compound is a compound containing at least one carbon-chlorine bond.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>organochlorine compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ion which is inorganic.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>inorganic ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cation which is inorganic.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>inorganic cation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An ion which is positively charged.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of polonium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>polonium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of antimony.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>antimony molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of thallum.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>thallium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of gallium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gallium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of indium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>indium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of astatine.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>astatine molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organofluorine compound is a compound containing at least one carbon-fluorine bond.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>organofluorine compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A homopolysaccharide which is composed of glucose residues.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polysaccharide, which is composed of a single type of monosaccharide residue. They are named by replacing the ending '-ose' of the sugar by '-an'.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of bismuth.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>bismuth molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of titanium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>titanium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of zirconium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>zirconium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of palladium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>palladium molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic dication of gadolinium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gadolinium (2+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic tetracation of gadolinium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gadolinium (4+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A compound or molecule which is used to enhance image formation of biological structures and functions for the detection and diagnosis of disease.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>diagnostic imaging agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A contrast agent, which has magnetic properties and provides contrast in images captured using MRI.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>MRI contrast agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
contrast agent in magnetic resonance imaging
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A contrast agent, which provides contrast in images captured using radioactive imaging techniques.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>radioactive imaging agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A contrast agent, which provides contrast in images captured using ultrasound imaging techniques.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>ultrasound contrast agent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A polyatomic entity which consists of two or more chemical elements.</ncicp:def-definition><ncicp:Definition_Review_Date>111020</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>heteroatomic molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of organonitrogen compound, which has two ?-haloalkyl groups bound to a nitrogen atom, as in (X?C2H2?C2H2)2NR.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nitrogen mustard</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A carboxamide is an amide derived from carboxylic acids. It is characterized by the presence of a carboxamide group. It has the structure R-C(=O)-NH2, R-C(=O)-NH-R' or R-C(=O)-N(-R")-R', where R,R',R" stands for organic groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An enzyme inhibitor, which inhibits the activity of protein kinase.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>protein kinase inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
inhibits phosphorylation in the signaling pathway, which regulates a variety of fundamental processes, such as cell growth, mitogenesis, metabolism, gene transcription, cell cycle control, and the immune response.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound which is derived from fluorescein by replacing a hydrogen atom of the benzene ring (the one that does not contain the hydroxyl groups), with an amine-reactive isothiocyanate group.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>fluorescein isothiocyanate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quinazoline compound is a derivative of quinazoline.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>quinazoline compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A hydrazone is an organic compound which is formally derived from aldehydes or ketones by replacing =O by =N-NH2 or =N-NH-R', and thus, characterized by a "hydrazone group." It has the structure R-C(=N-NH2)-R" or R-C(=N-NH-R')-R".</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A protein that contains a non-protein prosthetic group such as sugar, nucleic acid, lipid, or metal ion.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>conjugated protein</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
[definition source]: L. G. Wade Jr. Organic Chemistry 3rd Edition
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A diazo compound is an organic compound which is characterized by the presence of a diazo group. It has the structure R=[N+]=[N-], where R denotes an organic group..</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>diazo compound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A ketone which is a cyclic compound containing one or more ketone groups.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cyclic ketone</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of nitrogen mustard.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Tamoxifen is an organic compound, which has a parent hydride, stilbin; and which blocks the effects of the hormone estrogen in the body. It is used to prevent or delay the return of breast cancer or to control its spread.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An anthracycline which is (1S,3S)-3-acetyl-3,5,12-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-?-L-lyxo-hexopyranoside.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=O)H. The group is characteristic of an aldehyde wherein it is attached to the remaining part of the molecule via covalent bond with hydrogen or carbon atoms.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>aldehyde group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group, in which an oxygen atom is bonded to a hydrogen atom, and has the structure -OH. The group is characteristic of an organic hydroxy molecule wherein it is attached to a carbon atom via a single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hydroxyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A pteridine compound has a pteridine substructure; which has functional parent, L-glutamic acid; which has other substructures that classify it a monocarboxylic acid amide and a dicarboxylic acid.</ncicp:def-definition></ncicp:ComplexDefinition>
An antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities. Methotrexate binds to and inhibits the enzyme dihydrofolate reductase, resulting in inhibition of purine nucleotide and thymidylate synthesis and, subsequently, inhibition of DNA and RNA syntheses. Methotrexate also exhibits potent immunosuppressant activity although the mechanism(s) of actions is unclear.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A diterpenoid, which consists of a tetracyclic core called baccatin III, and an amide tail.</ncicp:def-definition></ncicp:ComplexDefinition>
Paclitaxel is isolated from the bark of the Pacific yew tree.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organofluorine compound, which has uracil as the funcitonal parent.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-definition>A mineral is a naturally occurring chemical substance formed through geological processes that has a characteristic chemical composition, a highly ordered atomic structure and specific physical properties.</ncicp:def-definition><ncicp:Definition_Review_Date>111020</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mineral which contains phosphate anions.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>phosphate mineral</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A liquid which can dissolve other substancees (solutes) without any change in their chemical composition.</ncicp:def-definition><ncicp:Definition_Review_Date>100728</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>CHEBI</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>solvent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polymer made by the polymerization of ethylene oxide.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>poly(ethylene glycol)</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=O)-OH. The group is characteristic of carboxylic acid compounds, wherein it is attached to a hydrogen atom or a carbon atom by a single covalent bond.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>carboxyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -X, where 'X' denotes a halogen atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>halo group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A functional group which has the structure -C(=O)-CH=CH2, and the group is characteristic of acryloyl compounds.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>acryloyl group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A polyketide which has a tetrahydronaphthacenedione ring structure attached by a glycosidic linkage to the amino sugar daunosamine.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An antineoplastic agent that slows down or prevents the formation and growth of blood or lymphatic vessels. In cancer therapy, angiogenesis inhibitors target blood vessels that supply tumors, thereby inhibiting tumor growth.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>angiogenesis inhibitor</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cyano group is a substituent group from hydrogen cyanide, and has the structure -C#N.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cyano group</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic dication of cobalt.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cobalt (2+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
(5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[(1R)-ethylidene]-?-D-glucopyranoside
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An organic compound or molecule, which has a functional parent, podophyllotoxin; which has substructure that classifies it as a beta-D-glucoside.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic hexacation of molybdenum.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>molybdenum (6+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monatomic monocation of silver.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>silver (1+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic monocation of gold.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gold (1+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic dication of europium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>europium (2+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic trication of gadolinium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gadolinium (3+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A type of quinazoline compound.</ncicp:def-definition></ncicp:ComplexDefinition>
removed 'has_role some epidermal growth factor receptor tyrosine kinase inhibitor'
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic hexacation of tungsten.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tungsten (6+) ion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A monoatomic anion which has ionic charge -4.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>monoatomic tetraanion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iron oxide with the chemical formula Fe2O3.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>iron (III) oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iron oxide with the chemical formula FeO.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>iron (II) oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An iron oxide with the chemical formula Fe3O4.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>iron (II,III) oxide</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molecular entity which contains one or more atoms of nitrogen.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nitrogen molecular entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phosphate mineral with the general formula Ca5(PO4)3X where X = OH, F or Cl.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A phosphate mineral with the formula Ca5(PO4)3(OH).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An absorption spectroscopic technique in which a beam of infrared light is used to irradiate a sample. The IR absorption spectra obtained with this technique, is used to identify compounds or investigate sample composition based on the correlation of absorption bands in the spectrum of the unknown compound with known absorption frequencies for specific types of bonds.</ncicp:def-definition><ncicp:Definition_Review_Date>100611</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>infrared spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
The technique is based on the fact that molecules have specific frequencies at which they rotate or vibrate corresponding to discrete energy levels (vibrational modes).
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An absorption spectroscopic technique in which the irradiating light has wavelengths within the ultraviolet and visible regions of the electromagnetic spectrum.</ncicp:def-definition><ncicp:Definition_Review_Date>100614</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>ultraviolet/visible spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which is carried out in vaccum, and is used to estimate the elemental composition and chemical state of the elements on the surface of a material by irradiating the material surface with a beam of soft monochromatic (magnesium/aluminum) X-rays and measuring the kinetic energy of photoelectrons emitted from the core orbitals of the surface elements within a few nm from the material surface.</ncicp:def-definition><ncicp:Definition_Review_Date>100615</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>x-ray photoelectron spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
Electron Spectroscopy for Chemical Analysis
Photoelectrons are collected and analyzed by the XPS instrument to produce a spectrum of emission intensity versus electron binding energy. Since each element has a unique set of binding energies, XPS can be used to identify the elements on the surface. Also, peak areas at nominal binding energies can be used to quantify concentration of the elements. Small shifts in these binding energies (chemical shifts) provide powerful information about sample chemical states and short-range chemistry .
[definition: based on NCIT, http://encyclopedia.thefreedictionary.com, http://www.chem.umd.edu/facility/xps.php]
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A separation technique for separation of mixtures, in which a mixture dissolved in a mobile liquid or gas medium, is passed through a stationary adsorbing medium to separate the components based on differential affinities of the components for the mobile medium and for the stationary medium.</ncicp:def-definition><ncicp:Definition_Review_Date>100616</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
[definition adapted from NCIT, WordNet, http://encyclopedia.thefreedictionary.com/chromatography]
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spectroscopic technique which is based on the detection of inelastically scattered monochromatic light from a laser in the visible, near infrared, or near ultraviolet range, by a substance (or sample under investigation). A laser beam of a given wavelength is used to irradiate a spot on the sample under investigation. The inelastically scattered light ( photons scattered at lower frequencies or higher wavelengths compared to that of the incident photons (Raman effect)), contains information about the energies of molecular vibrations and rotations, and these depend on the particular atoms or ions that comprise the molecule, the chemical bonds connect them, the symmetry of their molecule structure, and the physico-chemical environment where they reside.</ncicp:def-definition><ncicp:Definition_Review_Date>100527</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>Raman spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
[definition: adapted from http://epsc.wustl.edu/haskin-group/Raman/faqs.htm, http://encyclopedia.thefreedictionary.com]
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chromatography technique in which the mobile phase is a gas.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gas chromatography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atomic force microscopy technique in which the tip of the cantilever is in contact with the sample's surface. In the contact mode, the overall force between the tip and the surface is repulsive and it is kept constant during scanning by maintaining a constant deflection, and therefore constant height above the surface.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>contact atomic force microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
[definition: adapted from http://en.wikipedia.org, http://www.nanoscience.com/education/AFM.html]
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An atomic force microscopy technique in which the tip of the cantilever is not in contact with sample's surface. In non contact mode, the overall force between the tip and the surface is attractive. The cantilever is oscillated at a frequency slightly above its resonance frequency where the amplitude of oscillation is typically a few nanometers (<10 nm). The van der Waals forces, which are strongest from 1 nm to 10 nm above the surface, or any other long range force which extends above the surface acts to decrease the resonance frequency of the cantilever. This decrease in resonance frequency combined with the feedback loop system maintains a constant oscillation amplitude or frequency by adjusting the average tip-to-sample distance. Measuring the tip-to-sample distance at each (x,y) data point allows the scanning software to construct a topographic image of the sample surface.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>non contact atomic force micrsocopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A non contact atomic force microscopy technique based on the use of magnetic force microscope.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>magnetic force microscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An infrared spectroscopy where the beam of light that irradiates the sample has wavelengths within the near-infrared region of the electromagnetic spectrum.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>near-infrared spectroscopy</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A technique based on the disperson of light or electromagnetic radiation into a range of directions by virtue of its interaction with a material medium through which it passes.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>light scattering</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chromatography technique classified based on the phase of the mobile medium.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>chromatography by mobile phase state</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
chromatography by physical state of the mobile phase
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chromatography technique in which the mobile phase is a liquid.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>liquid chromatography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chromatography technique classified based on the mechanism of separation.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>chromatography by separation mechanism</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A chromatography technique which uses porous gels to separate solute molecules or particles based on size.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>size-exclusion chromatography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A liquid chromatography technique in which the sample is forced by a liquid (mobile phase) at high pressure, through a column that is packed with a solid stationary phase.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>high pressure liquid chromatography</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electrophoresis technique, in which a sample is introduced into a capillary tube and the components are separated by the application of high voltage. Due to the large surface to volume ratio, cooling is more efficient, allowing use of higher voltages. As a result, separation occurs more quickly and sensitivity is increased. The technique allows for separation of proteins, nucleic acids, and carbohydrates.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>capillary electrophoresis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.</ncicp:def-definition></ncicp:ComplexDefinition>
blood vessel formation from pre-existing blood vessels
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Elemental activity, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>molecular function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively and non-covalently with any nucleic acid.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nucleic acid binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any molecular function by which a gene product interacts selectively with DNA (deoxyribonucleic acid).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>DNA binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>antigen binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. [source: ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>enzyme activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>DNA topoisomerase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>DNA topoisomerase type II activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
DNA topoisomerase (ATP-hydrolyzing) activity
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>dihydrofolate reductase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. [source: MetaCyc:PROTEIN-KINASE-RXN]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>protein kinase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. [source: EC:2.7.10]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>protein tyrosine kinase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
5,10-methylenetetrahydrofolate:dUMP C-methyltransferase activity
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP. [source: EC:2.1.1.45]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>thymidylate synthase activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
methylenetetrahydrofolate:dUMP C-methyltransferase activity
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Combining with an extracellular or intracellular messenger to initiate a change in cell activity.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>receptor activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. [source: GOC:bf, GOC:ceb, ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>receptor binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
epidermal growth factor receptor binding
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with the epidermal growth factor receptor. [source: GOC:ai]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>epidermal growth factor receptor binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
transforming growth factor alpha receptor binding
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The selective, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). [source: GOC:go_curators]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>protein binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A material entity, which is the part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>Gene Ontology (GO)</ncicp:attr><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cellular component</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. [source: GO]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>extracellular space</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-definition>A material entity which is the basic structural and functional unit of all organisms. It includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.</ncicp:def-definition><ncicp:Definition_Review_Date>110830</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>thom510</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways involving DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. [source: ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>DNA metabolic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>DNA replication</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>DNA modification</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>DNA alkylation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The synthesis of either RNA on a template of DNA or DNA on a template of RNA. [source: ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The synthesis of RNA on a template of DNA.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>DNA-dependent transcription</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
regulation of DNA-dependent transcription
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that modulates the frequency, rate or extent of DNA-dependent transcription.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>regulation of DNA-dependent transcription</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Cellular uptake of extracellular materials within membrane-limited vacuoles or microvesicles.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The process whereby phagocytes engulf external particulate material. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle the cell and result in cell death. Apoptosis begins internally with condensation and subsequent fragmentation of the cell nucleus (blebbing) while the plasma membrane remains intact. Other characteristics of apoptosis include DNA fragmentation and the exposure of phosphatidyl serine on the cell surface. [source: GOC:go_curators, ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Progression through mitosis, the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother. [source: GOC:ma, ISBN:0198547684]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. [source: GOC:hb, GOC:pf]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cell adhesion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process that stops, prevents or reduces the frequency, rate or extent of cell adhesion.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>negative regulation of cell adhesion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
An inhibition which involves interference with, or restraint of, the activities of biologic molecules, biologic complexes, or subcellular components that promote the adherence of cells to surfaces or to other cells. [NCIT definition]
<ncicp:ComplexDefinition><ncicp:def-definition>For definition, please refer to the Gene Ontology (v. 1.1.2341).</ncicp:def-definition><ncicp:Definition_Review_Date>130522</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>GO (v. 1.1.2341)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>blood coagulation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton. [source: GOC:mah]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cytoskeletal protein binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>biological process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. [source: GOC:go_curators, ISBN:0198547684]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>metabolic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>negative regulation of DNA replication</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death. [source: GOC:ems]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cell death</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. [source: GOC:curators, ISBN:0198547684]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>biosynthetic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. [source: GOC:go_curators, GOC:isa_complete]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cellular process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Cell death resulting from activation of endogenous cellular processes. [source: GOC:lr]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>programmed cell death</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with monomeric or multimeric forms of tubulin, including microtubules. [source: GOC:clt]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tubulin binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. [source: ISBN:0198506732]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>RNA metabolic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The attachment of one cell to another cell via adhesion molecules. [source: GOC:hb]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cell-cell adhesion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops, prevents or reduces the frequency, rate or extent of angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>negative regulation of angiogenesis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. [source: GOC:isa_complete]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cell cycle process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cell cycle process comprising the steps by which a cell progresses through one of the biochemical and morphological phases and events that occur during successive cell replication or nuclear replication events. [source: GOC:isa_complete]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cell cycle phase</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with an estrogen receptor.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>estrogen receptor binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. [source: GOC:isa_complete]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>developmental process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. [source: GOC:mah]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>RNA biosynthetic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells. [source: GOC:mah]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cellular biopolymer metabolic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
cellular biopolymer biosynthetic process
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins, as carried out by individual cells. [source: GOC:mah]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cellular biopolymer biosynthetic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with a nuclear hormone receptor, a ligand-dependent receptor found in the nucleus of the cell. [source: GOC:bf]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>nuclear hormone receptor binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with a steroid hormone receptor. [source: GOC:bf]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>steroid hormone receptor binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
tumor necrosis factor biosynthetic process
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis. [source: GOC:jl, PMID:10891884]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>tumor necrosis factor biosynthetic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
tumor necrosis factor alpha biosynthesis
inhibition of tumor necrosis factor biosynthetic process
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>inhibition of tumor necrosis factor biosynthetic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with the microtubule constituent protein alpha-tubulin. [source: GOC:jl]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>alpha-tubulin binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with the microtubule constituent protein gamma-tubulin. [source: GOC:jl]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gamma-tubulin binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases the activity of an enzyme.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>positive regulation of enzyme activity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the activity of an enzyme.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>enzyme inhibition</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature, such as polysaccharides and proteins. [source: GOC:jl, http://en.wikipedia.org/]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>biopolymer metabolic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins. [source: GOC:jl, http://en.wikipedia.org/]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>biopolymer biosynthetic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
negative regulation of molecular function
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>negative regulation of molecular function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
positive regulation of molecular function
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>positive regulation of molecular function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways by which individual cells transform chemical substances. [source: GOC:go_curators]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cellular metabolic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. [source: GOC:jl]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cellular biosynthetic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases the frequency, rate or extent of DNA replication.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>positive regulation of DNA replication</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases angiogenesis.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>positive regulation of angiogenesis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases the frequency, rate or extent of cell adhesion.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>positive regulation of cell adhesion</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>negative regulation of mitosis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases the frequency, rate or extent of mitosis.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>positive regulation of mitosis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
negative regulation of DNA-dependent transcription
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops, prevents or reduces the frequency, rate or extent of DNA-dependent transcription.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>negative regulation of DNA-dependent transcription</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
down regulation of DNA-dependent transcription
down-regulation of DNA-dependent transcription
downregulation of DNA-dependent transcription
inhibition of DNA-dependent transcription
positive regulation of DNA-dependent transcription
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases the frequency, rate or extent of DNA-dependent transcription.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>positive regulation of DNA-dependent transcription</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
activation of DNA-dependent transcription
stimulation of DNA-dependent transcription
up regulation of DNA-dependent transcription
up-regulation of DNA-dependent transcription
upregulation of DNA-dependent transcription
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>folic acid metabolic process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with the microtubule constituent protein beta-tubulin. [source: GOC:krc]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>beta-tubulin binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
positive regulation of biological process
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that activates or increases the frequency, rate or extent of biological process.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>positive regulation of biological process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
negative regulation of biological process
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that stops, prevents or reduces the frequency, rate or extent of a biological process.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>negative regulation of biological process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. [source: GOC:dph, GOC:jic]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>anatomical structure formation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>regulation of biological process</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The process resulting in the physical partitioning and separation of a cell into daughter cells. [source: GOC:go_curators]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cell division</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Interacting selectively with a receptor for hormones. [source: GOC:ai]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>hormone receptor binding</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>regulation of molecular function</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cellular necrosis</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity inhering in an object by virtue of its ability to move or be moved freely.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity inhering in an object by virtue of the rate of change of its position.</ncicp:def-definition><ncicp:Definition_Review_Date>100429</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The rate at which an event occurs or is repeated over a particular period of time.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality inhering in a bearer by virtue of its physical magnitude.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 1-D extent quality which is equal to the vertical dimension of extension.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 1-D extent quality which is equal to the distance between two points.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality that inheres in a bearer in proportion to the amount of matter it contains. It is the property of a substance that causes it to have weight in a gravitational field.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A force inhering in an object with mass near a gravitational body.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality of the thermal energy of a system.</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity inhering in a bearer or a population, by virtue of the bearer's ability or inability to survive and develop normally or the number of surviving individuals in a given population.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition inhering in a bearer by virtue of its exhibiting photosensitivity.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 1-D extent quality which is equal to the dimension through an object as opposed to its length or width.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 3-D extent quality of the amount of 3-dimensional space an object occupies.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 1-D extent quality which is equal to the distance from one side of an object to another side which is opposite.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A disposition inhering to the bearer by virtue of its sensitivity to the action of radiant energy.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality which exists through action of continuants at the physical level of organisation.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>physical quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A physical quality which inhers to the bearer by virtue of some influence exerted by its mass.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity inhering in a object affecting its acceleration.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A wave parameter which is equal to the distance between repeating units of a wave pattern.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality that inheres in an object by virtue of how that object interacts with electromagnetic radiation.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>electromagnetic radiation quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A scalar optical quality which obtains by the magnitude of the light emitted by the bearer.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>luminous quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An EM radiation quality in which the EM radiation is within the fiat range of the spectrum visible deemed to be light.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>optical quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 2-D extent inhering in a bearer by virtue of its two dimensional extent.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality which is equal to the length of any straight line segment that passes through the center of a circle and whose endpoints are on the circular boundary.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A density quality which is equal to the mass exerting an influence on a given volume.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>mass density</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a cell's plasma membrane by virtue of the electrical potential difference across it.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>membrane potential</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity that is equal to the potential energy per unit charge associated with a static (time-invariant) electric field, also called the electrostatic potential.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>electric potential</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a bearer by virtue of vibration, as perceived by the sense of hearing.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>sound quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The frequency of transmitted vibrations.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>frequency of sound wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The speed at which sound travels in a given medium under specified conditions.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>speed of sound wave</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>The quotient of the speed of a sound wave divided by its frequency.</ncicp:def-definition><ncicp:Definition_Review_Date>100414</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>wavelength of sound</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 1-D extent downward or backward or inward.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality of the amount of 3-dimensional space a mass of substance occupies.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>specific volume</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality of the amount of 3-dimensional space a homogeneous substance containing 6.02 x 1023 atoms or molecules occupies.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>PATO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>molar volume</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A quality that inheres in a homogeneous substance containing 6.02 x 1023 atoms or molecules.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>molar mass</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity which is a property inhering in a material entity by virtue of its ability to exert an attractive or repulsive force on other material entities.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A magnetic behavior exhibited 1) by materials which produce magnetic fields to exert attractive or repulsive forces on other materials or 2) by materials which become magnetized when exposed to a magnetic field.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in an bearer by virtue of its extension in one dimension.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>1-D extent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in an bearer by virtue of its extenstion in two dimensions.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>2-D extent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in an bearer by virtue of its extenstion in three dimensions.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>3-D extent</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A 2-D extent quality which is equal to the distance around a given two-dimensional object.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality that inheres in an object by virtue of how that object interacts with radiation.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>radiation quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in an entity by virtue of it containing acid (hydrogen ions).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable property which inheres in a molecule that lacks affinity for water molecules, or has a tendency to repel or not to mix with water molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable property which inheres in a molecule that has a strong affinity to a water molecule, or has a tendency to mix with or wetted by water molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quality inhering in a bearer by virtue of its participation in movement.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>movement quality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A process involving the interconversion of chemical species.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>chemical reaction</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Luminescence arising from photoexcitation.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Photoluminescence which occurs essentially only during the irradiation of a substance by electromagnetic radiation.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A photoluminescence which is long-lived compared to fluorescence, and involves change in spin multiplicity, typically from triplet to singlet or vice versa. The luminescence from a quartet state to a doublet state is also phosphorescence. [source: http://goldbook.iupac.org/P04569.htm]</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>The decrease in rate of reaction brought about by the addition of a substance (inhibitor), by virtue of its effect on the concentration of a reactant, catalyst or reaction intermediate.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Spontaneous emission of radiation from an electronically or vibrationally excited species not in thermal equilibrium with its environment.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Luminescence resulting from a chemical reaction.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>Radioactive deactivation of an excited state of a material entity by which energy is transferred from the material entity to an electromagnetic field.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A quantitative measure of a property, which is a quantity chosen as a standard measure in terms of which other quantities (measured numerical values) are expressed in.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>unit of measurement</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the distance between two points.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>length unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of measurement which is a standard measure of the amount of matter/energy of a physical object.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>mass unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A base unit which is a standard measure of the dimension in which events occur in sequence.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>time unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the average kinetic energy of the particles in a sample of matter.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>temperature unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A base unit which is a standardized quantity of an element or compound with uniform composition.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>substance unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A length unit which is equal to the length of the path traveled by light in vacuum during a time interval of 1/299 792 458 of a second.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass unit which is equal to the mass of the International Prototype Kilogram kept by the BIPM at Svres, France.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to the duration of 9 192 631 770 periods of the radiation corresponding to the transition between the two hyperfine levels of the ground state of the caesium 133 atom.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A thermodynamic temperature unit which is equal to the fraction 1/273.16 of the thermodynamic temperature of the triple point of water.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A substance unit which is equal to the amount of substance of a molecular system which contains as many elementary entities as there are atoms in 0.012 kilogram of carbon 12.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A length unit which is equal to one hundredth of a meter or 10^[-2] m.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A length unit which is equal to one thousandth of a meter or 10^[-3] m.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A length unit which is equal to one millionth of a meter or 10^[-6] m.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A length unit which is equal to one thousandth of one millionth of a meter or 10^[-9] m.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A length unit which is equal to 10 [-10] m.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass unit which is equal to one thousandth of a kilogram or 10^[-3] kg.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass unit which is equal to one thousandth of a gram or 10^[-3] g.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass unit which is equal to one millionth of a gram or 10^[-6] g.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass unit which is equal to one thousandth of one millionth of a gram or 10^[-9] g.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A temperature unit on the Celsius scale based on which the freezing point of water is 0 degrees Celsius and the boiling point is 100 degree Celsius at standard conditions. Celsius scale has its zero at 273.15 K.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>degree celsius</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to one thousandth of a second or 10^[-3] s.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to one millionth of a second or 10^[-6] s.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time derived unit which is equal to 60 seconds.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to 3600 seconds or 60 minutes.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to 24 hours.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to 7 days.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is approximately equal to the length of time of one of cycle of the moon's phases which is taken to be equal to 30 days.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to 12 months.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A substance unit equal to a millionth of a mol or 10^[-6] mol.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A substance unit equal to a thousandth of a mol or 10^[-3] mol.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A substance unit equal to one thousandth of one millionth of a mole or 10^[-9] mol.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the amount of a 2-dimensional surface.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>area unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which represents a standard measurement of how much of a given substance there is mixed with another substance.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>concentration unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A density unit which is a standard measure of the mass of a substance in a given volume.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>mass density unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the mass of a homogeneous substance containing 6.02 x 1023 atoms or molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>molar mass unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the volume of a homogeneous substance containing 6.02 x 1023 atoms or molecules.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>molar volume unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A standard measure of the rate of movement. Speed is measured in the same physical units of measurement as velocity, but does not contain the element of direction that velocity has. Speed is thus the magnitude component of velocity.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>unit of velocity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A concentration unit which is a standard measure of the number of moles of a given substance per liter of solution.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>unit of molarity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of concentration which expresses a concentration of 1 mole of solute per liter of solution (mol/L).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of molarity which is equal to one thousandth of a molar or 10^[-3] M.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of molarity which is equal to one millionth of a molar or 10^[-6] M.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of molarity which is equal to one thousandth of one millionth of a molar or 10^[-9] M.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A concentration unit which is a standard measure of the number of moles of a given solute per kilogram of solvent.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>unit of molality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of concentration which expresses a concentration of a solution of 1 mole per kilogram of solvent (mol/kg).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molality unit which is equal to one thousandth of a molal or 10^[-3] m.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molality unit which is equal to one millionth of a molal or 10^[-6] m.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molality unit which is equal to one thousandth of one millionth of a molal or 10^[-9] m.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A concentration unit which is a standard measure of the number gram equivalents of solute per liter of solution.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>unit of normality</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of concentration which is one gram equivalent of a solute per liter of solution. A gram equivalent weight or equivalent is a measure of the reactive capacity of a given molecule.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An area unit which is equal to an area enclosed by a square with sides each 1 meter long.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>square meter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An area unit which is equal to one thousand of square meter or 10^[-3] m^[2].</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>square centimeter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An area unit which is equal to one millionth of a square meter or 10^[-6] m^[2].</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>square millimeter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in kilograms divided by the volume in cubic meters.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>kilogram per cubic meter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in grams divided by the volume in cubic centimeters.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gram per cubic centimeter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molar mass unit which is equal to one kilogram of mass of one mole of chemical element or chemical compound.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>kilogram per mole</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molar mass unit which is equal to one gram of mass of one mole of chemical element or chemical compound.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gram per mole</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molar volume unit which is equal to 1 cubic meter occupied by one mole of a substance in the form of a solid, liquid, or gas.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cubic meter per mole</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A molar volume unit which is equal to 1 cubic centimeter occupied by one mole of a substance in the form of a solid, liquid, or gas.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cubic centimeter per mole</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A speed/velocity unit which is equal to the speed of an object traveling 1 meter distance in one second.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>meter per second</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the amount of space occupied by any substance, whether solid, liquid, or gas.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>volume unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A volume unit which is equal to the volume of a cube with edges one meter in length. One cubic meter equals to 1000 liters.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cubic meter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A volume unit which is equal to one millionth of a cubic meter or 10^[-9] m^[3], or to 1 ml.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cubic centimeter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A volume unit which is equal to one thousandth of a liter or 10^[-3] L, or to 1 cubic centimeter.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A volume unit which is equal to one thousandth of a cubic meter or 10^[-3] m^[3], or to 1 decimeter.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A volume unit which is equal to one millionth of a liter or 10^[-6] L.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A volume unit which is equal to one thousandth of one millionth of a liter or 10^[-9] L.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the number of repetitive actions in a particular time.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>frequency unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A frequency unit which is equal to 1 complete cycle of a recurring phenomenon in 1 second.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of measurement for the force applied to accelerate a mass (an amount of matter).</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>force unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A force unit which is equal to the force required to cause an acceleration of 1m/s2 of a mass of 1 Kg in the direction of the force.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A time unit which is equal to one thousandth of one millionth of a second or 10^[-9] s.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A realizable entity which inheres in a chemical or element which represents the period over which the amount, activity or concentration of a specified chemical or element falls to half its original amount, activity or concentration. The realization is the observation of change in the concentration, activity or amount of the bearer.</ncicp:def-definition><ncicp:Definition_Review_Date>100430</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>half life</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A percentage unit of concentration which denotes the mass of a substance in a mixture as a percentage of the mass of the entire mixture.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>percent mass per mass</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A percentage unit concentration which denotes the mass of the substance in a mixture as a percentage of the volume of the entire mixture.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>percent mass per volume</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A percentage unit concentration which denotes the volume of the solute in mL per 100 mL of the resulting solution.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>percent volume per volume</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dimensionless concentration notation which describes the amount of one substance in another.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>parts per notation</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dimensionless concentration notation which denotes the amount of a given substance in a total amount of 1000 regardless of the units of measure as long as they are the same.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>parts per thousand</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dimensionless concentration notation which denotes the amount of a given substance in a total amount of 1,000,000 regardless of the units of measure used as long as they are the same or 1 part in 10^[6].</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>parts per million</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in grams divided by the volume in milliliter.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gram per milliliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in kilograms divided by the volume in liters.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>kilogram per liter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in grams divided by the volume in liters.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>gram per liter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass density unit which is equal to mass of an object in milligrams divided by the volume in milliliters.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>milligram per milliliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is a standard measure of the influence exerted by some mass.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>density unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of measurement of which is dimensionless.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>dimensionless unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A ratio unit which denotes numbers as fractions of 100.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A dimensionless unit which denotes a simple count of things.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A temperature unit on the Fahrenheit scale in which the freezing point of water is 32 degrees Fahrenheit and the boiling point is 212 degrees at standard conditions, placing the boiling and freezing points of water 180 degrees apart. -40 degrees Fahrenheit is equal to -40 degrees Celsius.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>degree Fahrenheit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>The logarithm of the reciprocal of hydrogen-ion concentration in gram atoms per liter. (source:Princeton WordNet)</ncicp:def-definition><ncicp:Definition_Review_Date>100427</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>WordNet</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A concentration unit which denotes the average cell number in a given volume.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>unit of cell concentration</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of cell concentration which is equal to one cell in a volume of 1 milliliter.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>cells per milliliter</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A standard measure of the work done per unit charge as a charge is moved between two points in an electric field.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>electric potential difference unit</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric potential difference unit which is equal to the work per unit charge. One volt is the potential difference required to move one coulomb of charge between two points in a circuit while using one joule of energy.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electrical charge unit which is equal to the amount of charge transferred by a current of 1 ampere in 1 second.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass unit which is equal to one twelfth of the mass of an unbound atom of the carbon-12 nuclide, at rest and in its ground state.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A mass unit which is equal to one thousand daltons.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of magnetic flux which is equal to the amount of flux that when linked with a single turn of wire for an interval of one second will induce an electromotive force of one volt.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of magnetic flux density which is equal to one weber per square meter.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of magnetic flux which is equal to 3600 Wb.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit of magnetic flux which is equal to one thousand volt-hours.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric potential difference unit which is equal to one thousandth of a volt or 10^[-3] V.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric potential difference unit which is equal to 10^[3] V.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An electric potential difference unit which is equal to one millionth of a volt or 10^[-6] V.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A unit which is an indicator of sound power per unit area.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>An entity is a thing which exists in reality.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An entity [bfo:Entity] that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
Examples: a heart, a person, the color of a tomato, the mass of a cloud, a symphony orchestra, the disposition of blood to coagulate, the lawn and atmosphere in front of our building
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A continuant [snap:Continuant] that is either dependent on one or other independent continuant [snap:IndependentContinuant] bearers or inheres in or is borne by other entities.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>dependent continuant</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
In order for a dependent continuant to exist, some other entity must exist.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity [snap:RealizableEntity] that essentially causes a specific process or transformation in the object [snap:Object] in which it inheres, under specific circumstances and in conjunction with the laws of nature. A general formula for dispositions is: X (object [snap:Object] has the disposition D to (transform, initiate a process) R under conditions C.</ncicp:def-definition></ncicp:ComplexDefinition>
Source:Robert Arp and Barry Smith "Function, Role and Disposition in Basic Formal Ontology" NATURE PROCEEDINGS, 2008.
The process occurs as a result of the object's physical structure. A disposition invariably or definitely leads to a certain result given certain circumstances (if not, then the realizable entity is a tendency and not a disposition).
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity [snap:RealizableEntity] the manifestation of which is an essentially end-directed activity of a continuant [snap:Continuant] entity in virtue of that continuant [snap:Continuant] entity being a specific kind of entity in the kind or kinds of contexts that it is made for.</ncicp:def-definition></ncicp:ComplexDefinition>
A realizable entity, which is a necessary function of the bearer, and it is realized as an end-directed activity (a process in which the bearer is a participant).
[source]: (1) BFO.owl 1.1; (2) Robert Arp and Barry Smith "Function, Role and Disposition in Basic Formal Ontology" NATURE PROCEEDINGS, 2008.
a function "f" is a realizable dependent continuant; it has a bearer which is an independent continuant; instances of Function F have realizations; each realization is a) a process in which the bearer is participant; b) that It occurs in virtue of the bearer's physical make-up or structure. c) and this physical make-up is something which the bearer possesses because of how it came into being.
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A continuant [snap:Continuant] that is dependent on one or other independent continuant [snap:IndependentContinuant] bearers. For every instance of A requires some instance of (an independent continuant [snap:IndependentContinuant] type) B but which instance of B serves can change from time to time. Examples: a certain PDF file that exists in different and in several hard drives</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>generically dependent continuant</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
Examples: a certain PDF file that exists in different and in several hard drives
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A continuant [snap:Continuant] that is a bearer of quality [snap:Quality] and realizable entity [snap:RealizableEntity] entities, in which other entities inhere and which itself cannot inhere in anything.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>independent continuant</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatial region [snap:SpatialRegion] with one dimension.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>one_dimensional_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A specifically dependent continuant [snap:SpecificallyDependentContinuant] that is exhibited if it inheres in an entity or entities at all (a categorical property).</ncicp:def-definition></ncicp:ComplexDefinition>
Example: compound x is related to organic compound through the relation "presence of carbon"; here, the quality that inheres in compound x is organic)
Examples: the color of a tomato, the ambient temperature of air, the circumference of a waist, the shape of a nose, the mass of a piece of gold, the weight of a chimpanzee
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A specifically dependent continuant [snap:SpecificallyDependentContinuant] that inheres in continuant [snap:Continuant] entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances.</ncicp:def-definition></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>realizable entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
Source: (1) BFO.owl v. 1.1; (2) Robert Arp and Barry Smith "Function, Role and Disposition in Basic Formal Ontology" NATURE PROCEEDINGS, 2008.
realizable entities are defined by the fact that they can be realized (manifested, actualized, executed) in occurrents of corresponding sorts.
<ncicp:ComplexDefinition><ncicp:def-source>NPO</ncicp:def-source><ncicp:def-definition>A realizable entity [snap:RealizableEntity] the manifestation of which brings about some result or end that is not essential to a continuant [snap:Continuant] in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant [snap:Continuant] in some kinds of natural, social or institutional contexts.</ncicp:def-definition></ncicp:ComplexDefinition>
At the instance-level, a role y is filled by x which is an instance of an independent continuant( x which takes the role of y: x is the filler, y is the role). A role y has a context P (e.g. an occurrent in which x is a participant). Every role term has its own qualities and behavior, given the context.
role is a realizable_entity whose manifestation brings about some result or end that is not typical of its bearer in virtue of the latter's physical structure. Rather role is played by an instance of the corresponding kind of continuant entity because this entity is in some special natural, social or institutional set of circumstances. (Source: Robert Arp and Barry Smith "Function, Role and Disposition in Basic Formal Ontology" NATURE PROCEEDINGS, 2008.)
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A continuant [snap:Continuant] that is neither bearer of quality [snap:Quality] entities nor inheres in any other entities.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>spatial_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A continuant [snap:Continuant] that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>specifically dependent continuant</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
Synonyms: property, trope, mode; Examples: the mass of a cloud, the smell of mozzarella, the liquidity of blood, the color of a tomato, the disposition of fish to decay, the role of being a doctor, the function of the heart in the body: to pump blood, to receive de-oxygenated and oxygenated blood, etc.
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatial region [snap:SpatialRegion] with three dimensions.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>three_dimensional_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
Examples: a cube-shaped part of space, a sphere-shaped part of space.
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatial region [snap:SpatialRegion] with two dimensions.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>two_dimensional_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatial region [snap:SpatialRegion] with no dimensions.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>zero_dimensional_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatiotemporal region [span:SpatiotemporalRegion] that has temporal and spatial dimensions such that all points within the spatiotemporal region are mediately or immediately connected to all other points within the same spatiotemporal region [span:SpatiotemporalRegion].</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>connected_spatiotemporal_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A temporal region [span:TemporalRegion] every point of which is mediately or immediately connected with every other point of which.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>connected_temporal_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
Examples: the 1970s years, the time from the beginning to the end of a heart attack, the time taken by cellular meiosis.
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A processual entity [span:ProcessualEntity] that is part of a process but that does not have bona fide beginnings and endings corresponding to real discontinuities.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>fiat process part</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
is it synonymous with "stage" which refers to temporally distinguised parts of an occurrent (eg., "infancy", "childhood", "adolescence", "adulthood" in the "life of a human being")?
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An entity [bfo:Entity] that has temporal parts and that happens, unfolds or develops through time. Sometimes also called perdurants.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
Examples: the life of an organism, a surgical operation as processual context for a nosocomical infection, the spatiotemporal context occupied by a process of cellular meiosis, the most interesting part of Van Gogh's life, the spatiotemporal region occupied by the development of a cancer tumor
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A processual entity [span:ProcessualEntity] that is a maximally connected spatiotemporal whole and has bona fide beginnings and endings corresponding to real discontinuities.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A processual entity [span:ProcessualEntity] that is a mereological sum of process [span:Process] entities and possesses non-connected boundaries.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>process aggregate</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A processual entity [span:ProcessualEntity] that is the fiat or bona fide instantaneous temporal process boundary.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>process boundary</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An occurrent [span:Occurrent] consisting of a characteristic spatial shape inhering in some arrangement of other occurrent [span:Occurrent] entities. Processual context [span:ProcessualContext] entities are characteristically entities at or in which other occurrent [span:Occurrent] entities can be located or occur.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>processual_context</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
Examples: The processual context for a given manipulation occurring as part of an experiment is made of processual entities which occur in parallel, are not necessarily all parts of the experiment themselves and may involve continuant [snap:Continuant] entities which are in the spatial vicinity of the participants in the experiment. An instance of a processual context [span:ProcessualContext] is a mixture of processual entity [span:ProcessualEntity] which stand as surrounding environments for other processual entity [span:ProcessualEntity] entities. The class processual context [span:ProcessualContext] is the analogous among occurrent [span:Occurrent] entities to the class site [snap:Site] among continuant [snap:Continuant] entities.
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An occurrent [span:Occurrent] that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm><ncicp:term-name>processual entity</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A spatiotemporal region [span:Spatiotemporal Region] that has spatial and temporal dimensions and every spatial and temporal point of which is not connectedd with every other spatial and temporal point of which.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>scattered_spatiotemporal_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A temporal region [span:TemporalRegion] every point of which is not mediately or immediately connected with every other point of which.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>scattered_temporal_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
Examples: The time occupied by the indiviual games of the World Cup.
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A connected spatiotemporal region [span:ConnectedSpatiotemporalRegion] at a specific moment.</ncicp:def-definition><ncicp:Definition_Review_Date>100405</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>spatiotemporal_instant</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>spatiotemporal_interval</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An occurrent [span:Occurrent] at or in which processual entity [span:ProcessualEntity] entities can be located.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>spatiotemporal_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A connected temporal region [span:ConnectedTemporalRegion] comprising a single moment of time.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>temporal_instant</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
Examples: right now, the moment at which a finger is detached in an industrial accident, the moment at which a child is born, the moment of death.
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>A connected temporal region [span:ConnectedTemporalRegion] lasting for more than a single moment of time.</ncicp:def-definition><ncicp:Definition_Review_Date>100406</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>temporal_interval</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
Examples: any continuous temporal duration during which a process occurs.
<ncicp:ComplexDefinition xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:def-definition>An occurrent [span:Occurrent] that is part of time.</ncicp:def-definition><ncicp:Definition_Review_Date>100428</ncicp:Definition_Review_Date><ncicp:def-source>NPO</ncicp:def-source><ncicp:attr>BFO (v. 1.1)</ncicp:attr><ncicp:Definition_Reviewer_Name>Dennis Thomas</ncicp:Definition_Reviewer_Name></ncicp:ComplexDefinition>
<ncicp:ComplexTerm xmlns:ncicp="http://ncicb.nci.nih.gov/xml/owl/EVS/ComplexProperties.xsd#"><ncicp:term-name>temporal_region</ncicp:term-name><ncicp:term-group>PT</ncicp:term-group><ncicp:term-source>NCI</ncicp:term-source></ncicp:ComplexTerm>
Examples: the time it takes to run a marathon, the duration of a surgical procedure, the moment of death.