--- name: designing-the-analysis description: Use when you have an approved research question and need a concrete analysis plan, before touching outcome data or fitting any model --- # Designing the Analysis ## Overview Write a comprehensive analysis plan assuming the analyst has zero context for this project and questionable statistical taste. Document everything they need: which datasets and variables, how each construct is computed, the exact model or test, the sample size / power justification, which confounds are handled and how, the decision rules, and the planned figures. Give them the whole thing as bite-sized steps. DRY. YAGNI. Pre-register. Validate pipelines on known data. Commit frequently. Assume they are a capable programmer but know almost nothing about this domain, this dataset, or good statistical design. **Announce at start:** "I'm using the designing-the-analysis skill to create the analysis plan." **Save plans to:** `docs/science-superpowers/plans/YYYY-MM-DD-.md` ## Scope Check If the question document still bundles several independent investigations, stop and split it — one plan per question. Each plan should produce an interpretable, self-contained result. ## Inputs You Need First - The approved question document (`docs/science-superpowers/questions/...`) - The prior-work survey: the adopted method, the confound list, and a prior effect size for powering If you don't have a prior effect size, the design must include how you will justify the sample size anyway (smallest effect of interest, precision target, or a sensitivity analysis). ## Artifact & Data-Flow Structure Before defining steps, map the pipeline. Data flows one direction: **raw → cleaned → derived → results**. - List the scripts/notebooks you will create and what each is responsible for. One responsibility each. - Name the data artifacts at each stage. Raw data is immutable; every transform writes a new artifact. - Identify where the train/test or discovery/confirmation split happens (if any) and lock it before any modeling. - Keep files focused. A 600-line "do everything" notebook is a design smell. ## Confound & Validity Plan For each known confound from the survey, state how it is handled: measured and adjusted for, stratified, matched, design-excluded, or explicitly acknowledged as a limitation. "We'll see" is not a plan. State the threats to validity you are accepting and why. ## Power / Sample Size State the target effect size, alpha, desired power, and the resulting required N — or, for a fixed existing sample, the minimum detectable effect at the planned power. If underpowered, say so and decide with your human partner whether to proceed (e.g., reframe as estimation, not a hypothesis test). ## Bite-Sized Step Granularity **Each step is one action (2-5 minutes).** Every step that touches data is paired with a *validation* — the science analog of watching a test fail then pass: - "Write the data-loading code" — step - "Run it; confirm row/column counts match the known dataset shape" — step - "Write the cleaning transform" — step - "Validate: assert no rows silently dropped, ranges within expected bounds" — step - "Validate the pipeline on simulated data with a known ground-truth effect; confirm it recovers the effect" — step - "Commit" — step The simulated-data validation step is mandatory for any nontrivial estimator or model: if you never watched your pipeline recover a known signal, you don't know it works. ## Plan Document Header **Every plan MUST start with this header:** ```markdown # [Question] Analysis Plan > **For agentic workers:** REQUIRED SUB-SKILL: pre-register this plan with science-superpowers:preregistering-analysis BEFORE execution. Then use science-superpowers:subagent-driven-analysis (recommended) or science-superpowers:executing-analysis to run it step-by-step. Steps use checkbox (`- [ ]`) syntax for tracking. **Question:** [the falsifiable question, one sentence] **Design:** [observational/experimental; cross-sectional/longitudinal; the comparison] **Data:** [datasets, sample, unit of analysis] **Primary analysis:** [the one model/test that answers the question] **Decision rule:** [exactly what result confirms vs. disconfirms H1] --- ``` ## Task Structure ````markdown ### Task N: [Analysis component] **Artifacts:** - Create: `analysis/exact_script.py` - Reads: `data/raw/exact_file.csv` (immutable) - Writes: `data/derived/exact_output.parquet` - [ ] **Step 1: Write the loading/transform code** ```python df = pd.read_csv("data/raw/exact_file.csv") clean = df[df["value"].between(0, 100)] ``` - [ ] **Step 2: Validate the step** Run: `python analysis/exact_script.py --check` Expected: `rows in: 10342, rows out: 10298, dropped: 44 (out-of-range)` — dropped count matches the known data-quality issue, not silent loss. - [ ] **Step 3: Run the primary model exactly as specified** ```python model = smf.ols("outcome ~ exposure + age + site", data=clean).fit() ``` - [ ] **Step 4: Apply the pre-registered decision rule** The estimate for `exposure` is interpreted against the rule fixed in the pre-registration — not re-decided here. - [ ] **Step 5: Commit** ```bash git add analysis/exact_script.py data/derived/exact_output.parquet git commit -m "analysis: primary model for exposure effect" ``` ```` ## No Placeholders Every step must contain the actual content the analyst needs. These are **plan failures** — never write them: - "TBD", "choose an appropriate test", "handle outliers as needed", "tune the model" - "Run statistics on the above" without naming the test and the variables - "Adjust for confounders" without naming which and how - "Similar to Task N" (repeat the specifics — steps may be read out of order) - Any decision rule that depends on the result you haven't seen yet (that is HARKing; fix it in the design) ## Self-Review After writing the plan, re-read the question document with fresh eyes and check the plan against it: 1. **Coverage:** Does a task answer the question? Does every hypothesis have an analysis? 2. **Researcher degrees of freedom:** Is every analytic choice (test, covariates, exclusions, transformations, cutoffs) specified in advance? List any that are still open and close them. 3. **Confound coverage:** Is every surveyed confound handled by a task? 4. **Placeholder scan:** Any of the failures above? Fix them. 5. **Consistency:** Do variable names, file paths, and the decision rule match across tasks? Fix issues inline. If a question requirement has no task, add the task. ## Handoff The plan is not ready to execute until its predictions and decision rules are locked. **REQUIRED NEXT SKILL:** Use `science-superpowers:preregistering-analysis` to freeze the confirmatory hypotheses, predictions, and decision rules before any outcome is observed. Execution happens only after that.