# Data Operations ## Quick Navigation - [Safety and lifecycle](#safety-model) - [Transfer tool selection](#transfer-tool-selection) - [Small transfers](#small-transfers-with-dx) - [Upload Agent](#upload-agent) - [Download Agent](#download-agent) - [Python transfers](#python-upload-and-download) - [Search and metadata](#search) - [Records and folders](#records) - [Cloning and archival](#cloning) - [Deletion](#deletion) - [Batch checklist](#batch-operation-checklist) ## Safety Model DNAnexus data objects live in projects or other data containers. Before a mutation: 1. Resolve the project to a `project-...` ID. 2. Resolve every path to an object ID. 3. Detect duplicate names. 4. Inspect state, archival state, size, and relevant metadata. 5. Confirm source/destination permissions and restrictions. 6. Show exact IDs and impact for deletion, cloning, archival, or egress. Names and paths are convenient for humans but are not immutable identifiers. Use IDs in automation. ## Object Lifecycle Files use: ```text open → closing → closed ``` - `open`: parts/content can still be uploaded. - `closing`: finalization is in progress; content cannot be read or written. - `closed`: content is immutable and available to download/share. Files must be closed before they can be read or cloned. They may be submitted as job inputs while open or closing, but the job remains `waiting_on_input` until closure. Open/closing files inactive for about 24 hours are considered abandoned and are later deleted by the platform. When a data object closes, content plus types, details/links, and visibility become fixed. User-editable metadata such as name, properties, and tags can still be managed according to permissions. Records may intentionally remain open when mutable structured details are required. Document this exception because open records weaken reproducibility. ## Transfer Tool Selection | Workload | Tool | |---|---| | One or a few small files | `dx upload`, `dx download` | | Multiple files or a file larger than 50 MB | Upload Agent (`ua`) | | Many/large/long-running downloads | Download Agent (`dx-download-agent`) | | Custom Python automation | `dxpy` | Use platform transfer agents when resumability and per-part integrity matter. ## Small Transfers with `dx` Upload: ```bash dx upload "sample.fastq.gz" \ --path "project-xxxx:/raw/sample.fastq.gz" \ --property "sample_id=S001" \ --tag "raw" ``` Download: ```bash dx download "project-xxxx:/results/sample.bam" \ --output "sample.bam" ``` Use quoted full paths. If a name is non-unique, use the object ID. For scripts, use `--brief` or machine-readable output where supported instead of parsing human-formatted tables. Current `dx` warns when a download or generated download URL targets a file flagged as malicious. Stop on that warning unless the user approves a containment procedure that prevents execution and protects the local system. ## Upload Agent Upload Agent is resumable and uses parallel connections. Important behavior: - Uncompressed files are compressed by default. - `.gz` is appended to the remote name. - Already compressed inputs are not recompressed. - `--do-not-compress` preserves the original bytes/name behavior. - Repeating the same command resumes a matching incomplete transfer. - `--wait-on-close` blocks until uploaded file objects are closed. - Per-part `Content-MD5` is verified by the platform. Example: ```bash ua \ --project "project-xxxx" \ --folder "/raw" \ --wait-on-close \ --progress \ "sample.fastq.gz" ``` For an uncompressed file that must not be transformed: ```bash ua \ --project "project-xxxx" \ --folder "/raw" \ --do-not-compress \ --wait-on-close \ "reference.fa" ``` Do not run `ua --env` in captured output because it displays the active token. Treat any Upload Agent `--auth-token` value and the toolkit `DX_SECURITY_CONTEXT` as secrets. Use `--do-not-resume` only when creating a deliberate second copy. Otherwise let the agent resume interrupted uploads. ## Download Agent Download Agent consumes a BZIP2-compressed JSON manifest. Use the manifest creation utility from the official `dnanexus/dxda` release and review its resolved file set before starting egress. Download Agent checks the secret `DX_API_TOKEN` and otherwise falls back to `~/.dnanexus_config/environment.json`. This is a Download Agent-specific variable; do not assume it configures Upload Agent, `dx`, or `dxpy`. ```bash dx-download-agent download "manifest.json.bz2" dx-download-agent progress "manifest.json.bz2" dx-download-agent inspect "manifest.json.bz2" ``` `inspect` revalidates downloaded parts against manifest checksums. If a part is missing or corrupt, rerun `download`. Before a large download: - Confirm local free space. - Confirm data egress approval and cost. - Confirm download restrictions/TRE policy. - Check that all files are live and closed. - Review the manifest for unexpected projects or PHI. - Use a token that remains valid for the expected transfer duration. Do not place an API token in a Docker command line or committed compose file. ## Python Upload and Download ```python from pathlib import Path import dxpy project_id = "project-xxxx" remote = dxpy.upload_local_file( "sample.fastq.gz", project=project_id, folder="/raw", properties={"sample_id": "S001"}, tags=["raw"], wait_on_close=True, show_progress=True, ) dxpy.download_dxfile( remote, str(Path("downloads") / "sample.fastq.gz"), project=project_id, show_progress=True, ) ``` `project` on download is also a billing/context hint. Pass it when the same file has copies in multiple projects or the billing context matters. Read a remote file as a stream: ```python import dxpy with dxpy.open_dxfile("file-xxxx", project="project-xxxx") as stream: first_chunk = stream.read(1024) ``` `DXFile.open_file()` is not a current dxpy method; use `dxpy.open_dxfile()`. ## Search ### CLI ```bash dx find data \ --class file \ --path "project-xxxx:/results" \ --name "*.bam" \ --name-mode glob ``` Use `dx find data --help` from the installed toolkit for current filter flags. ### dxpy ```python import dxpy results = dxpy.find_data_objects( classname="file", project="project-xxxx", folder="/results", recurse=True, name="*.bam", name_mode="glob", state="closed", archival_state="live", describe={ "fields": { "name": True, "size": True, "created": True, "archivalState": True, "properties": True, } }, limit=500, ) for result in results: print(result["id"], result["describe"]["name"]) ``` Critical semantics: - Default `name_mode` is `"exact"`. - Use `"glob"` for `*` and `?`. - Use `"regexp"` only with a reviewed, bounded pattern. - Results are generators and dxpy handles API pagination. - Without `limit`, dxpy can traverse the full result set. - `describe` adds API work and may expose metadata; request only needed fields. - `archival_state` requires a file class plus project/folder scope. The API defaults to pages of at most 1000. DNAnexus documents a 200 API calls/second account limit; implement bounded concurrency and exponential backoff rather than flooding the service. ## Metadata Properties are string key/value pairs; tags are strings. ```python import dxpy file_obj = dxpy.DXFile("file-xxxx", project="project-xxxx") file_obj.set_properties( { "sample_id": "S001", "pipeline_version": "2.4.1", } ) file_obj.add_tags(["validated", "release-2026-07"]) file_obj.rename("S001.aligned.bam") ``` Avoid direct identifiers in tags/properties when projects contain PHI. Follow the organization's approved metadata model. Metadata updates affect discovery and provenance. Review overwrite semantics before replacing a full property/detail mapping. ## Records Create a closed immutable record: ```python import dxpy record = dxpy.new_dxrecord( project="project-xxxx", folder="/metadata", name="run-001", types=["RunMetadata"], details={ "pipeline": "rna-seq", "pipeline_version": "2.4.1", }, close=True, ) ``` Create an open record only when continued mutation is required: ```python record = dxpy.new_dxrecord( project="project-xxxx", name="mutable-status", details={"state": "queued"}, close=False, ) record.set_details({"state": "running"}) record.close() ``` Closing fixes details and links. For append-only provenance, prefer creating a new versioned record instead of mutating a shared open record. ## Folders ```python import dxpy project = dxpy.DXProject("project-xxxx") project.new_folder("/analysis/run-001/results", parents=True) listing = project.list_folder( "/analysis/run-001", describe={"fields": {"name": True, "state": True}}, ) ``` Move exact IDs: ```python project.move( "/analysis/run-001/final", objects=["file-xxxx", "record-yyyy"], ) ``` Never use a broad recursive operation until the folder listing and count have been shown to the user. ## Cloning ```python import dxpy source = dxpy.DXFile("file-xxxx", project="project-source") clone = source.clone( project="project-destination", folder="/imports", ) print(clone.get_id()) ``` Requirements and caveats: - Source object must be closed. - `VIEW` or higher is needed on the source. - `UPLOAD` or higher is needed on the destination. - Restricted projects/TREs can forbid cloning. - Databases cannot be cloned. - Hidden linked objects may be cloned with their visible parent. - Archive transitions can block cloning. - Cross-`billTo` cloning of archived data requires live objects. - The clone is independent; removing the source does not remove the clone. Use `dx cp` for project-to-project copies when folder structure is the primary interface: ```bash dx cp \ "project-source:/results" \ "project-destination:/imports" ``` Confirm source, destination, file count, and billing entity first. ## Archival Archive and unarchive are billable/storage-affecting operations and may take time: ```bash dx archive "project-xxxx:/old-results/sample.bam" dx unarchive "project-xxxx:/old-results/sample.bam" ``` Before archiving: - Check whether active workflows, collaborators, or published outputs need it. - Check all copies and billing behavior. - Confirm the target is a file or intended folder. Before unarchiving: - Confirm retrieval cost and required completion time. - Avoid launching dependent jobs until files return to `live`. Programmatic wrappers exist as `dxpy.api.project_archive()` and `dxpy.api.project_unarchive()`, but prefer the CLI for one-off human-reviewed operations. ## Deletion Data removal is irreversible on the platform. Removing a visible object can also remove orphaned hidden linked objects. Safe sequence: 1. List the exact IDs. 2. Describe each object. 3. Confirm project, folder, size, state, and linked-object impact. 4. Ask for confirmation. 5. Remove by ID. 6. Verify absence and record an audit note outside the deleted data. Project controls are distinct: - `protected=true` restricts project-data deletion to project administrators; when false, contributors can also delete. - `destroyProtected=true` blocks destruction of the entire project regardless of requester permissions until an authorized administrator clears it. - Project destruction removes every object. It fails while jobs are active unless `terminateJobs=true`, which force-terminates them. Never clear `destroyProtected`, set `terminateJobs=true`, or destroy a project as an implicit extension of an object-deletion request. Each requires separate explicit authorization after listing active jobs, project protections, billing context, and total data impact. Python: ```python import dxpy project = dxpy.DXProject("project-xxxx") project.remove_objects(["file-xxxx"], force=False) ``` Recursive folder removal: ```python project.remove_folder("/obsolete/run-001", recurse=True, force=False) ``` This is dangerous. Removing `/` recursively deletes all container contents. Never generate or execute that operation. The API removes at most 10,000 objects per folder-removal request. Do not automatically loop partial deletion without rechecking the remaining scope. Project deletion, permission changes, and delegated `overrideProjectAccess` deletion require separate explicit authorization. ## Batch Operation Checklist - Bound result count and concurrency. - Materialize and review the target ID list before mutation. - Preserve a machine-readable manifest of source IDs and destinations. - Make operations restartable/idempotent. - Do not treat duplicate names as one object. - Check file state after upload. - Validate transfer integrity. - Capture failures without logging credentials or sensitive metadata. - Reconcile completed, skipped, and failed IDs. - Respect service limits and use exponential backoff.