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" ], "text/plain": [ "| \n", " | GSM2199887 | \n", "GSM2199888 | \n", "GSM2199889 | \n", "GSM2199890 | \n", "GSM2199891 | \n", "GSM2199892 | \n", "GSM2199893 | \n", "GSM2199894 | \n", "GSM2199895 | \n", "GSM2199896 | \n", "GSM2199897 | \n", "GSM2199898 | \n", "GSM2199899 | \n", "GSM2199900 | \n", "GSM2199901 | \n", "
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A1BG | \n", "226 | \n", "213 | \n", "226 | \n", "239 | \n", "184 | \n", "320 | \n", "216 | \n", "176 | \n", "155 | \n", "114 | \n", "121 | \n", "88 | \n", "104 | \n", "95 | \n", "101 | \n", "
| A1CF | \n", "5 | \n", "6 | \n", "5 | \n", "6 | \n", "5 | \n", "2 | \n", "8 | \n", "2 | \n", "1 | \n", "3 | \n", "3 | \n", "3 | \n", "3 | \n", "6 | \n", "2 | \n", "
| A2M | \n", "269 | \n", "293 | \n", "286 | \n", "87 | \n", "77 | \n", "120 | \n", "9880 | \n", "8700 | \n", "11563 | \n", "8414 | \n", "9400 | \n", "8165 | \n", "26724 | \n", "26608 | \n", "27077 | \n", "
| A2ML1 | \n", "8 | \n", "12 | \n", "7 | \n", "8 | \n", "24 | \n", "13 | \n", "14 | \n", "9 | \n", "9 | \n", "27 | \n", "3 | \n", "5 | \n", "10 | \n", "11 | \n", "8 | \n", "
| A2MP1 | \n", "15 | \n", "10 | \n", "13 | \n", "14 | \n", "21 | \n", "28 | \n", "18 | \n", "8 | \n", "12 | \n", "24 | \n", "18 | \n", "9 | \n", "9 | \n", "8 | \n", "6 | \n", "
| \n", " | Sample Title | \n", "cell type | \n", "expression | \n", "
|---|---|---|---|
| Sample_geo_accession | \n", "\n", " | \n", " | \n", " |
| GSM2199887 | \n", "ET-1 | \n", "A375 melanoma cells | \n", "empty vector | \n", "
| GSM2199888 | \n", "ET-2 | \n", "A375 melanoma cells | \n", "empty vector | \n", "
| GSM2199889 | \n", "ET-3 | \n", "A375 melanoma cells | \n", "empty vector | \n", "
| GSM2199890 | \n", "GDF6-1 | \n", "A375 melanoma cells | \n", "GDF6 overexpression | \n", "
| GSM2199891 | \n", "GDF6-2 | \n", "A375 melanoma cells | \n", "GDF6 overexpression | \n", "
| GSM2199892 | \n", "GDF6-3 | \n", "A375 melanoma cells | \n", "GDF6 overexpression | \n", "
| GSM2199893 | \n", "ETGFP-1 | \n", "A375 melanoma cells | \n", "empty vector + EGFP knockdown | \n", "
| GSM2199894 | \n", "ETGFP-2 | \n", "A375 melanoma cells | \n", "empty vector + EGFP knockdown | \n", "
| GSM2199895 | \n", "ETGFP-3 | \n", "A375 melanoma cells | \n", "empty vector + EGFP knockdown | \n", "
| GSM2199896 | \n", "ETB11-1 | \n", "A375 melanoma cells | \n", "empty vector + GDF6 knockdown | \n", "
| GSM2199897 | \n", "ETB11-2 | \n", "A375 melanoma cells | \n", "empty vector + GDF6 knockdown | \n", "
| GSM2199898 | \n", "ETB11-3 | \n", "A375 melanoma cells | \n", "empty vector + GDF6 knockdown | \n", "
| GSM2199899 | \n", "DVDB11-1 | \n", "A375 melanoma cells | \n", "SMAD1 overexpression + GDF6 knockdown | \n", "
| GSM2199900 | \n", "DVDB11-2 | \n", "A375 melanoma cells | \n", "SMAD1 overexpression + GDF6 knockdown | \n", "
| GSM2199901 | \n", "DVDB11-3 | \n", "A375 melanoma cells | \n", "SMAD1 overexpression + GDF6 knockdown | \n", "
| \n", " | logFC | \n", "AveExpr | \n", "P-value | \n", "FDR | \n", "
|---|---|---|---|---|
| Gene | \n", "\n", " | \n", " | \n", " | \n", " |
| *SMAD1 | \n", "6.10 | \n", "5.57 | \n", "1.087706e-08 | \n", "0.000256 | \n", "
| *SAMD11 | \n", "6.52 | \n", "2.46 | \n", "1.452305e-08 | \n", "0.000256 | \n", "
| *MSX2 | \n", "2.69 | \n", "3.48 | \n", "4.390148e-08 | \n", "0.000281 | \n", "
| *MMP1 | \n", "1.67 | \n", "6.38 | \n", "4.881783e-08 | \n", "0.000281 | \n", "
| *ST8SIA5 | \n", "2.14 | \n", "5.09 | \n", "5.178203e-08 | \n", "0.000281 | \n", "
| *CRLF1 | \n", "4.16 | \n", "3.92 | \n", "5.419116e-08 | \n", "0.000281 | \n", "
| *COL9A2 | \n", "4.89 | \n", "3.64 | \n", "5.591942e-08 | \n", "0.000281 | \n", "
| *TNFRSF19 | \n", "1.83 | \n", "5.98 | \n", "7.371608e-08 | \n", "0.000325 | \n", "
| *CDH19 | \n", "2.03 | \n", "6.16 | \n", "9.340449e-08 | \n", "0.000366 | \n", "
| *EDNRB | \n", "1.61 | \n", "6.65 | \n", "1.582547e-07 | \n", "0.000443 | \n", "
| *LOR | \n", "7.64 | \n", "-2.24 | \n", "1.583724e-07 | \n", "0.000443 | \n", "
| *MAL2 | \n", "-3.14 | \n", "3.89 | \n", "1.601700e-07 | \n", "0.000443 | \n", "
| *XYLT1 | \n", "2.36 | \n", "7.40 | \n", "1.775517e-07 | \n", "0.000443 | \n", "
| *ANKH | \n", "2.01 | \n", "7.94 | \n", "1.776711e-07 | \n", "0.000443 | \n", "
| *NOV | \n", "-1.72 | \n", "6.49 | \n", "1.885586e-07 | \n", "0.000443 | \n", "
| *MAF | \n", "2.21 | \n", "4.51 | \n", "2.217176e-07 | \n", "0.000477 | \n", "
| *ADAMTS9 | \n", "2.47 | \n", "4.40 | \n", "2.301614e-07 | \n", "0.000477 | \n", "
| *CHGB | \n", "-1.43 | \n", "4.00 | \n", "2.452064e-07 | \n", "0.000480 | \n", "
| *FLT1 | \n", "3.34 | \n", "5.50 | \n", "2.633249e-07 | \n", "0.000488 | \n", "
| *CPNE4 | \n", "4.30 | \n", "0.16 | \n", "3.241837e-07 | \n", "0.000541 | \n", "
| *PMEPA1 | \n", "2.96 | \n", "6.18 | \n", "3.635727e-07 | \n", "0.000541 | \n", "
| *SEL1L3 | \n", "2.64 | \n", "6.28 | \n", "3.784010e-07 | \n", "0.000541 | \n", "
| *CDH6 | \n", "-3.27 | \n", "1.63 | \n", "3.915043e-07 | \n", "0.000541 | \n", "
| *SYTL5 | \n", "2.62 | \n", "7.28 | \n", "4.366782e-07 | \n", "0.000541 | \n", "
| *LPL | \n", "1.64 | \n", "4.68 | \n", "4.446082e-07 | \n", "0.000541 | \n", "
| *PRUNE2 | \n", "2.54 | \n", "4.11 | \n", "4.547342e-07 | \n", "0.000541 | \n", "
| *MEF2C | \n", "1.80 | \n", "5.45 | \n", "4.554696e-07 | \n", "0.000541 | \n", "
| *GRM8 | \n", "3.90 | \n", "3.46 | \n", "4.755255e-07 | \n", "0.000541 | \n", "
| *SPHK1 | \n", "1.86 | \n", "4.38 | \n", "4.781651e-07 | \n", "0.000541 | \n", "
| *TRBV24-1 | \n", "4.99 | \n", "-3.57 | \n", "4.786182e-07 | \n", "0.000541 | \n", "
| *KANK4 | \n", "5.83 | \n", "-3.15 | \n", "5.148164e-07 | \n", "0.000541 | \n", "
| *CPA4 | \n", "-2.09 | \n", "9.67 | \n", "5.261906e-07 | \n", "0.000541 | \n", "
| *SLC16A4 | \n", "1.19 | \n", "4.76 | \n", "5.306740e-07 | \n", "0.000541 | \n", "
| *TMTC1 | \n", "-1.09 | \n", "4.46 | \n", "5.352834e-07 | \n", "0.000541 | \n", "
| *YPEL2 | \n", "1.09 | \n", "3.87 | \n", "5.643611e-07 | \n", "0.000541 | \n", "
| *ADRB2 | \n", "-1.33 | \n", "3.30 | \n", "5.830343e-07 | \n", "0.000541 | \n", "
| *NWD1 | \n", "4.38 | \n", "-0.62 | \n", "5.985121e-07 | \n", "0.000541 | \n", "
| *HHIPL2 | \n", "3.33 | \n", "-0.16 | \n", "6.065740e-07 | \n", "0.000541 | \n", "
| *PXYLP1 | \n", "2.43 | \n", "3.92 | \n", "6.081971e-07 | \n", "0.000541 | \n", "
| *JAG1 | \n", "1.94 | \n", "6.64 | \n", "6.404088e-07 | \n", "0.000541 | \n", "
| *DIAPH2 | \n", "0.93 | \n", "4.24 | \n", "6.464822e-07 | \n", "0.000541 | \n", "
| *TMEM200A | \n", "-1.71 | \n", "4.04 | \n", "6.628906e-07 | \n", "0.000541 | \n", "
| *NR4A1 | \n", "2.53 | \n", "5.81 | \n", "6.658620e-07 | \n", "0.000541 | \n", "
| *TGFA | \n", "1.65 | \n", "8.65 | \n", "6.841261e-07 | \n", "0.000541 | \n", "
| *RP11-726G1.1 | \n", "2.17 | \n", "5.01 | \n", "6.907719e-07 | \n", "0.000541 | \n", "
| *B3GAT1 | \n", "2.80 | \n", "3.53 | \n", "7.297954e-07 | \n", "0.000549 | \n", "
| *CECR2 | \n", "1.96 | \n", "2.40 | \n", "7.318550e-07 | \n", "0.000549 | \n", "
| *LHFPL2 | \n", "0.83 | \n", "6.38 | \n", "7.582523e-07 | \n", "0.000557 | \n", "
| *RASD1 | \n", "3.75 | \n", "1.24 | \n", "8.419564e-07 | \n", "0.000597 | \n", "
| *TMTC2 | \n", "0.93 | \n", "5.88 | \n", "8.472299e-07 | \n", "0.000597 | \n", "
| *ARL4C | \n", "-1.19 | \n", "6.15 | \n", "1.012178e-06 | \n", "0.000676 | \n", "
| *IGFBP5 | \n", "1.98 | \n", "9.00 | \n", "1.014875e-06 | \n", "0.000676 | \n", "
| *SERPINE2 | \n", "0.57 | \n", "13.10 | \n", "1.049999e-06 | \n", "0.000676 | \n", "
| *KIAA1549L | \n", "1.11 | \n", "6.49 | \n", "1.072939e-06 | \n", "0.000676 | \n", "
| *DLX1 | \n", "1.83 | \n", "4.11 | \n", "1.095345e-06 | \n", "0.000676 | \n", "
| *MUC7 | \n", "2.52 | \n", "3.07 | \n", "1.100304e-06 | \n", "0.000676 | \n", "
| *PCK1 | \n", "4.82 | \n", "2.59 | \n", "1.118914e-06 | \n", "0.000676 | \n", "
| *C1QTNF3 | \n", "2.34 | \n", "1.75 | \n", "1.128517e-06 | \n", "0.000676 | \n", "
| *RAI2 | \n", "5.27 | \n", "-3.43 | \n", "1.131371e-06 | \n", "0.000676 | \n", "
| *CCBE1 | \n", "-2.70 | \n", "3.50 | \n", "1.165164e-06 | \n", "0.000684 | \n", "
| *ARHGAP29 | \n", "-2.21 | \n", "5.12 | \n", "1.247830e-06 | \n", "0.000698 | \n", "
| *CGA | \n", "4.57 | \n", "5.29 | \n", "1.265688e-06 | \n", "0.000698 | \n", "
| *SLIT2 | \n", "-1.83 | \n", "5.15 | \n", "1.267963e-06 | \n", "0.000698 | \n", "
| *TMEM2 | \n", "1.24 | \n", "9.04 | \n", "1.268338e-06 | \n", "0.000698 | \n", "
| *UNC5B | \n", "3.31 | \n", "3.62 | \n", "1.292647e-06 | \n", "0.000701 | \n", "
| *AD000671.6 | \n", "4.26 | \n", "-3.93 | \n", "1.364909e-06 | \n", "0.000718 | \n", "
| *UPK3B | \n", "-1.82 | \n", "1.44 | \n", "1.381818e-06 | \n", "0.000718 | \n", "
| *DGKI | \n", "3.35 | \n", "2.69 | \n", "1.401078e-06 | \n", "0.000718 | \n", "
| *SCUBE3 | \n", "3.38 | \n", "5.45 | \n", "1.405493e-06 | \n", "0.000718 | \n", "
| *DOCK11 | \n", "-1.12 | \n", "3.87 | \n", "1.507918e-06 | \n", "0.000749 | \n", "
| *DLEU7 | \n", "2.16 | \n", "-0.09 | \n", "1.508858e-06 | \n", "0.000749 | \n", "
| *ADAM12 | \n", "-0.88 | \n", "6.24 | \n", "1.545098e-06 | \n", "0.000756 | \n", "
| *SLC44A1 | \n", "0.94 | \n", "6.50 | \n", "1.768827e-06 | \n", "0.000854 | \n", "
| *PCSK1 | \n", "1.13 | \n", "9.22 | \n", "1.894730e-06 | \n", "0.000886 | \n", "
| *GLI3 | \n", "1.29 | \n", "6.67 | \n", "1.917165e-06 | \n", "0.000886 | \n", "
| *ID2 | \n", "4.30 | \n", "2.94 | \n", "1.922254e-06 | \n", "0.000886 | \n", "
| *ID3 | \n", "2.58 | \n", "5.74 | \n", "1.946228e-06 | \n", "0.000886 | \n", "
| *LRRC17 | \n", "-1.14 | \n", "5.94 | \n", "1.964583e-06 | \n", "0.000886 | \n", "
| *ATP2B4 | \n", "0.92 | \n", "8.01 | \n", "1.990947e-06 | \n", "0.000886 | \n", "
| *BNC2 | \n", "-1.01 | \n", "5.24 | \n", "2.059197e-06 | \n", "0.000886 | \n", "
| *MAOB | \n", "2.78 | \n", "1.58 | \n", "2.060919e-06 | \n", "0.000886 | \n", "
| *A2M | \n", "1.87 | \n", "8.95 | \n", "2.114004e-06 | \n", "0.000886 | \n", "
| *MARCH4 | \n", "-1.61 | \n", "3.33 | \n", "2.133478e-06 | \n", "0.000886 | \n", "
| *FRMD3 | \n", "1.52 | \n", "3.58 | \n", "2.133884e-06 | \n", "0.000886 | \n", "
| *SVEP1 | \n", "-1.04 | \n", "4.67 | \n", "2.137794e-06 | \n", "0.000886 | \n", "
| *KIAA1211L | \n", "4.85 | \n", "-3.64 | \n", "2.208409e-06 | \n", "0.000899 | \n", "
| *PRICKLE1 | \n", "-1.45 | \n", "3.24 | \n", "2.243698e-06 | \n", "0.000899 | \n", "
| *CAPN5 | \n", "1.14 | \n", "5.11 | \n", "2.281703e-06 | \n", "0.000899 | \n", "
| *DLX2 | \n", "3.38 | \n", "2.70 | \n", "2.287705e-06 | \n", "0.000899 | \n", "
| *ACTC1 | \n", "7.88 | \n", "-0.13 | \n", "2.296431e-06 | \n", "0.000899 | \n", "
| *COL4A1 | \n", "1.45 | \n", "8.83 | \n", "2.354272e-06 | \n", "0.000910 | \n", "
| *TENM3 | \n", "0.68 | \n", "7.00 | \n", "2.375524e-06 | \n", "0.000910 | \n", "
| *PXDN | \n", "-1.63 | \n", "7.05 | \n", "2.482962e-06 | \n", "0.000941 | \n", "
| *SEMA5A | \n", "1.51 | \n", "2.65 | \n", "2.518762e-06 | \n", "0.000944 | \n", "
| *TRBV25-1 | \n", "4.46 | \n", "-3.83 | \n", "2.622645e-06 | \n", "0.000971 | \n", "
| *BTBD3 | \n", "0.58 | \n", "8.43 | \n", "2.665739e-06 | \n", "0.000971 | \n", "
| *PTPRJ | \n", "0.98 | \n", "7.12 | \n", "2.671607e-06 | \n", "0.000971 | \n", "
| *ATP10B | \n", "2.58 | \n", "2.94 | \n", "2.700007e-06 | \n", "0.000971 | \n", "
| *GATA2 | \n", "1.60 | \n", "3.58 | \n", "2.876906e-06 | \n", "0.001007 | \n", "
| *HS6ST3 | \n", "3.48 | \n", "2.24 | \n", "2.897855e-06 | \n", "0.001007 | \n", "
| Rank | \n", "Transcription Factor | \n", "P-value | \n", "FDR | \n", "Target | \n", "
|---|---|---|---|---|
| 1 | \n", "SUZ12* | \n", "0.000002 | \n", "0.000861 | \n", "55 upregulated targets | \n", "
| 2 | \n", "JARID2* | \n", "0.000049 | \n", "0.010152 | \n", "50 upregulated targets | \n", "
| 3 | \n", "EZH2 | \n", "0.001680 | \n", "0.130203 | \n", "50 upregulated targets | \n", "
| 4 | \n", "RNF2 | \n", "0.001680 | \n", "0.130203 | \n", "50 upregulated targets | \n", "
| 5 | \n", "TRIM28 | \n", "0.007348 | \n", "0.506177 | \n", "7 upregulated targets | \n", "
| 6 | \n", "MTF2 | \n", "0.023198 | \n", "1.000000 | \n", "91 upregulated targets | \n", "
| 7 | \n", "EED | \n", "0.028285 | \n", "1.000000 | \n", "30 upregulated targets | \n", "
| 8 | \n", "FOXP1 | \n", "0.137000 | \n", "1.000000 | \n", "2 upregulated targets | \n", "
| 9 | \n", "CTNNB1 | \n", "0.220175 | \n", "1.000000 | \n", "6 upregulated targets | \n", "
| 10 | \n", "CBX2 | \n", "0.278689 | \n", "1.000000 | \n", "24 upregulated targets | \n", "
| 11 | \n", "PHC1 | \n", "0.290677 | \n", "1.000000 | \n", "26 upregulated targets | \n", "
| 12 | \n", "TP53 | \n", "0.307369 | \n", "1.000000 | \n", "31 upregulated targets | \n", "
| 13 | \n", "CTBP2 | \n", "0.321294 | \n", "1.000000 | \n", "29 upregulated targets | \n", "
| 14 | \n", "DROSHA | \n", "0.354067 | \n", "1.000000 | \n", "13 upregulated targets | \n", "
| 15 | \n", "BMI1 | \n", "0.401310 | \n", "1.000000 | \n", "28 upregulated targets | \n", "
| 16 | \n", "RXR | \n", "0.415908 | \n", "1.000000 | \n", "15 upregulated targets | \n", "
| 17 | \n", "TP63 | \n", "0.464677 | \n", "1.000000 | \n", "5 upregulated targets | \n", "
| 18 | \n", "EWS-FLI1 | \n", "0.467574 | \n", "1.000000 | \n", "15 upregulated targets | \n", "
| 19 | \n", "KLF2 | \n", "0.477476 | \n", "1.000000 | \n", "3 upregulated targets | \n", "
| 20 | \n", "KLF5 | \n", "0.477476 | \n", "1.000000 | \n", "3 upregulated targets | \n", "
| 21 | \n", "KLF4 | \n", "0.483858 | \n", "1.000000 | \n", "3 upregulated targets | \n", "
| 22 | \n", "UBF1/2 | \n", "0.522480 | \n", "1.000000 | \n", "50 upregulated targets | \n", "
| 23 | \n", "PPARD | \n", "0.535483 | \n", "1.000000 | \n", "5 upregulated targets | \n", "
| 24 | \n", "HOXD13 | \n", "0.544609 | \n", "1.000000 | \n", "5 upregulated targets | \n", "
| 25 | \n", "WT1 | \n", "0.558137 | \n", "1.000000 | \n", "5 upregulated targets | \n", "
| 26 | \n", "BCAT | \n", "0.561403 | \n", "1.000000 | \n", "16 upregulated targets | \n", "
| 27 | \n", "GBX2 | \n", "0.575712 | \n", "1.000000 | \n", "7 upregulated targets | \n", "
| 28 | \n", "RING1B | \n", "0.582443 | \n", "1.000000 | \n", "49 upregulated targets | \n", "
| 29 | \n", "TAF15 | \n", "0.585451 | \n", "1.000000 | \n", "6 upregulated targets | \n", "
| 30 | \n", "GATA1 | \n", "0.618246 | \n", "1.000000 | \n", "1 upregulated targets | \n", "
| 31 | \n", "FOXA1 | \n", "0.627310 | \n", "1.000000 | \n", "14 upregulated targets | \n", "
| 32 | \n", "STAT6 | \n", "0.646221 | \n", "1.000000 | \n", "1 upregulated targets | \n", "
| 33 | \n", "THRA | \n", "0.657768 | \n", "1.000000 | \n", "4 upregulated targets | \n", "
| 34 | \n", "ZFP322A | \n", "0.661864 | \n", "1.000000 | \n", "2 upregulated targets | \n", "
| 35 | \n", "BCL11B | \n", "0.663725 | \n", "1.000000 | \n", "1 upregulated targets | \n", "
| 36 | \n", "TDRD3 | \n", "0.672676 | \n", "1.000000 | \n", "15 upregulated targets | \n", "
| 37 | \n", "CHD7 | \n", "0.688264 | \n", "1.000000 | \n", "3 upregulated targets | \n", "
| 38 | \n", "CBP | \n", "0.690579 | \n", "1.000000 | \n", "23 upregulated targets | \n", "
| 39 | \n", "IRF4 | \n", "0.690579 | \n", "1.000000 | \n", "23 upregulated targets | \n", "
| 40 | \n", "EGR1 | \n", "0.691228 | \n", "1.000000 | \n", "6 upregulated targets | \n", "
| 41 | \n", "ERG | \n", "0.694768 | \n", "1.000000 | \n", "7 upregulated targets | \n", "
| 42 | \n", "MYCN | \n", "0.699180 | \n", "1.000000 | \n", "5 upregulated targets | \n", "
| 43 | \n", "ESR1 | \n", "0.706908 | \n", "1.000000 | \n", "2 upregulated targets | \n", "
| 44 | \n", "VDR | \n", "0.716553 | \n", "1.000000 | \n", "5 upregulated targets | \n", "
| 45 | \n", "PAX3-FKHR | \n", "0.726747 | \n", "1.000000 | \n", "24 upregulated targets | \n", "
| 46 | \n", "SRY | \n", "0.729180 | \n", "1.000000 | \n", "4 upregulated targets | \n", "
| 47 | \n", "CDX2 | \n", "0.732990 | \n", "1.000000 | \n", "7 upregulated targets | \n", "
| 48 | \n", "SALL1 | \n", "0.742115 | \n", "1.000000 | \n", "2 upregulated targets | \n", "
| 49 | \n", "P300 | \n", "0.748248 | \n", "1.000000 | \n", "46 upregulated targets | \n", "
| 50 | \n", "NR3C1 | \n", "0.768201 | \n", "1.000000 | \n", "20 upregulated targets | \n", "
| Rank | \n", "Transcription Factor | \n", "P-value | \n", "FDR | \n", "Target | \n", "
|---|---|---|---|---|
| 1 | \n", "SUZ12 | \n", "0.074089 | \n", "1.0 | \n", "20 upregulated targets | \n", "
| 2 | \n", "EZH2 | \n", "0.403408 | \n", "1.0 | \n", "52 upregulated targets | \n", "
| 3 | \n", "CBX8 | \n", "0.696522 | \n", "1.0 | \n", "47 upregulated targets | \n", "
| 4 | \n", "NR2F2 | \n", "0.719267 | \n", "1.0 | \n", "3 upregulated targets | \n", "
| 5 | \n", "ZZZ3 | \n", "0.791836 | \n", "1.0 | \n", "4 upregulated targets | \n", "
| 6 | \n", "REST | \n", "0.797937 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 7 | \n", "BCL3 | \n", "0.811025 | \n", "1.0 | \n", "10 upregulated targets | \n", "
| 8 | \n", "ZC3H11A | \n", "0.823056 | \n", "1.0 | \n", "16 upregulated targets | \n", "
| 9 | \n", "CBX2 | \n", "0.872583 | \n", "1.0 | \n", "43 upregulated targets | \n", "
| 10 | \n", "ESR1 | \n", "0.876384 | \n", "1.0 | \n", "12 upregulated targets | \n", "
| 11 | \n", "ZKSCAN1 | \n", "0.876477 | \n", "1.0 | \n", "4 upregulated targets | \n", "
| 12 | \n", "CEBPB | \n", "0.878374 | \n", "1.0 | \n", "5 upregulated targets | \n", "
| 13 | \n", "MEF2C | \n", "0.902607 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 14 | \n", "GATA1 | \n", "0.921133 | \n", "1.0 | \n", "13 upregulated targets | \n", "
| 15 | \n", "FOXM1 | \n", "0.925379 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 16 | \n", "ESRRA | \n", "0.946065 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 17 | \n", "MAFK | \n", "0.956719 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 18 | \n", "GATA3 | \n", "0.965375 | \n", "1.0 | \n", "21 upregulated targets | \n", "
| 19 | \n", "STAT5A | \n", "0.973568 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 20 | \n", "RELA | \n", "0.977659 | \n", "1.0 | \n", "12 upregulated targets | \n", "
| 21 | \n", "RFX5 | \n", "0.981186 | \n", "1.0 | \n", "6 upregulated targets | \n", "
| 22 | \n", "MYOG | \n", "0.982142 | \n", "1.0 | \n", "3 upregulated targets | \n", "
| 23 | \n", "NR3C1 | \n", "0.982908 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 24 | \n", "TCF12 | \n", "0.982957 | \n", "1.0 | \n", "13 upregulated targets | \n", "
| 25 | \n", "TEAD4 | \n", "0.985348 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 26 | \n", "MEF2A | \n", "0.986491 | \n", "1.0 | \n", "3 upregulated targets | \n", "
| 27 | \n", "POLR3A | \n", "0.992438 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 28 | \n", "STAT1 | \n", "0.992498 | \n", "1.0 | \n", "3 upregulated targets | \n", "
| 29 | \n", "JUND | \n", "0.992946 | \n", "1.0 | \n", "3 upregulated targets | \n", "
| 30 | \n", "FOXA2 | \n", "0.993090 | \n", "1.0 | \n", "3 upregulated targets | \n", "
| 31 | \n", "FOSL1 | \n", "0.994493 | \n", "1.0 | \n", "3 upregulated targets | \n", "
| 32 | \n", "ZNF263 | \n", "0.995435 | \n", "1.0 | \n", "12 upregulated targets | \n", "
| 33 | \n", "ETS1 | \n", "0.995802 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 34 | \n", "RAD21 | \n", "0.996359 | \n", "1.0 | \n", "33 upregulated targets | \n", "
| 35 | \n", "CTCF | \n", "0.997840 | \n", "1.0 | \n", "17 upregulated targets | \n", "
| 36 | \n", "HNF4G | \n", "0.997906 | \n", "1.0 | \n", "6 upregulated targets | \n", "
| 37 | \n", "SRF | \n", "0.998195 | \n", "1.0 | \n", "3 upregulated targets | \n", "
| 38 | \n", "HSF1 | \n", "0.998243 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 39 | \n", "BCL11A | \n", "0.998337 | \n", "1.0 | \n", "16 upregulated targets | \n", "
| 40 | \n", "HDAC2 | \n", "0.998493 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 41 | \n", "GATA2 | \n", "0.998574 | \n", "1.0 | \n", "3 upregulated targets | \n", "
| 42 | \n", "SREBF1 | \n", "0.998767 | \n", "1.0 | \n", "4 upregulated targets | \n", "
| 43 | \n", "BATF | \n", "0.998831 | \n", "1.0 | \n", "8 upregulated targets | \n", "
| 44 | \n", "NFIC | \n", "0.998961 | \n", "1.0 | \n", "6 upregulated targets | \n", "
| 45 | \n", "STAT2 | \n", "0.999001 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 46 | \n", "FOSL2 | \n", "0.999332 | \n", "1.0 | \n", "3 upregulated targets | \n", "
| 47 | \n", "NFE2 | \n", "0.999337 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 48 | \n", "TCF7L2 | \n", "0.999521 | \n", "1.0 | \n", "4 upregulated targets | \n", "
| 49 | \n", "EP300 | \n", "0.999663 | \n", "1.0 | \n", "5 upregulated targets | \n", "
| 50 | \n", "RXRA | \n", "0.999701 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| Rank | \n", "Transcription Factor | \n", "P-value | \n", "FDR | \n", "Target | \n", "
|---|---|---|---|---|
| 1 | \n", "GRHL3* | \n", "0.000070 | \n", "0.048515 | \n", "20 downregulated targets | \n", "
| 2 | \n", "IRF6* | \n", "0.000070 | \n", "0.048515 | \n", "20 downregulated targets | \n", "
| 3 | \n", "HAND1 | \n", "0.000204 | \n", "0.292982 | \n", "19 upregulated targets | \n", "
| 4 | \n", "FOXD4L6 | \n", "0.001489 | \n", "0.345092 | \n", "17 downregulated targets | \n", "
| 5 | \n", "SOX15 | \n", "0.001489 | \n", "0.345092 | \n", "17 downregulated targets | \n", "
| 6 | \n", "HEYL | \n", "0.001489 | \n", "0.345092 | \n", "17 downregulated targets | \n", "
| 7 | \n", "EHF | \n", "0.001489 | \n", "0.345092 | \n", "17 downregulated targets | \n", "
| 8 | \n", "ZNF479 | \n", "0.003686 | \n", "0.466154 | \n", "16 downregulated targets | \n", "
| 9 | \n", "SNAI1 | \n", "0.003686 | \n", "0.466154 | \n", "16 downregulated targets | \n", "
| 10 | \n", "MYF5 | \n", "0.003686 | \n", "0.466154 | \n", "16 downregulated targets | \n", "
| 11 | \n", "ARNTL2 | \n", "0.003686 | \n", "0.466154 | \n", "16 downregulated targets | \n", "
| 12 | \n", "DSP | \n", "0.003686 | \n", "0.466154 | \n", "16 downregulated targets | \n", "
| 13 | \n", "SOX8 | \n", "0.001489 | \n", "0.533639 | \n", "17 upregulated targets | \n", "
| 14 | \n", "OLIG2 | \n", "0.001489 | \n", "0.533639 | \n", "17 upregulated targets | \n", "
| 15 | \n", "OLIG1 | \n", "0.001489 | \n", "0.533639 | \n", "17 upregulated targets | \n", "
| 16 | \n", "MEF2C | \n", "0.008592 | \n", "0.853717 | \n", "15 downregulated targets | \n", "
| 17 | \n", "TP63 | \n", "0.008592 | \n", "0.853717 | \n", "15 downregulated targets | \n", "
| 18 | \n", "ZNF750 | \n", "0.008592 | \n", "0.853717 | \n", "15 downregulated targets | \n", "
| 19 | \n", "PAX2 | \n", "0.008592 | \n", "0.999513 | \n", "15 upregulated targets | \n", "
| 20 | \n", "HEY1 | \n", "0.008592 | \n", "0.999513 | \n", "15 upregulated targets | \n", "
| 21 | \n", "ADAMTS17 | \n", "0.018802 | \n", "0.999513 | \n", "14 upregulated targets | \n", "
| 22 | \n", "ZSCAN20 | \n", "0.018802 | \n", "0.999513 | \n", "14 upregulated targets | \n", "
| 23 | \n", "JRKL | \n", "0.018802 | \n", "0.999513 | \n", "14 upregulated targets | \n", "
| 24 | \n", "POU4F1 | \n", "0.018802 | \n", "0.999513 | \n", "14 upregulated targets | \n", "
| 25 | \n", "CSDC2 | \n", "0.018802 | \n", "0.999513 | \n", "14 upregulated targets | \n", "
| 26 | \n", "NEUROD4 | \n", "0.018802 | \n", "0.999513 | \n", "14 upregulated targets | \n", "
| 27 | \n", "NRL | \n", "0.018802 | \n", "0.999513 | \n", "14 upregulated targets | \n", "
| 28 | \n", "FOXR1 | \n", "0.018802 | \n", "0.999513 | \n", "14 downregulated targets | \n", "
| 29 | \n", "ZNF679 | \n", "0.018802 | \n", "0.999513 | \n", "14 downregulated targets | \n", "
| 30 | \n", "LEUTX | \n", "0.018802 | \n", "0.999513 | \n", "14 downregulated targets | \n", "
| 31 | \n", "BNC1 | \n", "0.018802 | \n", "0.999513 | \n", "14 downregulated targets | \n", "
| 32 | \n", "MSC | \n", "0.018802 | \n", "0.999513 | \n", "14 downregulated targets | \n", "
| 33 | \n", "FBN1 | \n", "0.018802 | \n", "0.999513 | \n", "14 downregulated targets | \n", "
| 34 | \n", "ZC3H10 | \n", "0.038521 | \n", "0.999513 | \n", "13 upregulated targets | \n", "
| 35 | \n", "ETV2 | \n", "0.038521 | \n", "0.999513 | \n", "13 upregulated targets | \n", "
| 36 | \n", "EVX2 | \n", "0.038521 | \n", "0.999513 | \n", "13 upregulated targets | \n", "
| 37 | \n", "HILS1 | \n", "0.038521 | \n", "0.999513 | \n", "13 upregulated targets | \n", "
| 38 | \n", "NFYA | \n", "0.038521 | \n", "0.999513 | \n", "13 upregulated targets | \n", "
| 39 | \n", "SOX30 | \n", "0.038521 | \n", "0.999513 | \n", "13 upregulated targets | \n", "
| 40 | \n", "SHOX2 | \n", "0.038521 | \n", "0.999513 | \n", "13 upregulated targets | \n", "
| 41 | \n", "IRX6 | \n", "0.038521 | \n", "0.999513 | \n", "13 upregulated targets | \n", "
| 42 | \n", "HAND2 | \n", "0.038521 | \n", "0.999513 | \n", "13 upregulated targets | \n", "
| 43 | \n", "BCL6B | \n", "0.038521 | \n", "0.999513 | \n", "13 upregulated targets | \n", "
| 44 | \n", "MITF | \n", "0.038521 | \n", "0.999513 | \n", "13 upregulated targets | \n", "
| 45 | \n", "SOX10 | \n", "0.038521 | \n", "0.999513 | \n", "13 upregulated targets | \n", "
| 46 | \n", "BMP2 | \n", "0.038521 | \n", "0.999513 | \n", "13 upregulated targets | \n", "
| 47 | \n", "ZNF575 | \n", "0.038521 | \n", "0.999513 | \n", "13 downregulated targets | \n", "
| 48 | \n", "KLF17 | \n", "0.038521 | \n", "0.999513 | \n", "13 downregulated targets | \n", "
| 49 | \n", "ZSCAN4 | \n", "0.038521 | \n", "0.999513 | \n", "13 downregulated targets | \n", "
| 50 | \n", "OVOL2 | \n", "0.038521 | \n", "0.999513 | \n", "13 downregulated targets | \n", "
| Rank | \n", "Kinase | \n", "P-value | \n", "FDR | \n", "Substrate | \n", "
|---|---|---|---|---|
| 1 | \n", "ACVR1 | \n", "0.025000 | \n", "0.356250 | \n", "1 upregulated substrates | \n", "
| 2 | \n", "BMPR1A | \n", "0.025000 | \n", "0.356250 | \n", "1 upregulated substrates | \n", "
| 3 | \n", "FLT1 | \n", "0.025000 | \n", "0.356250 | \n", "1 upregulated substrates | \n", "
| 4 | \n", "ROR2 | \n", "0.025000 | \n", "0.356250 | \n", "1 upregulated substrates | \n", "
| 5 | \n", "ADRBK2 | \n", "0.008753 | \n", "0.420000 | \n", "2 downregulated substrates | \n", "
| 6 | \n", "GRK5 | \n", "0.012052 | \n", "0.420000 | \n", "2 downregulated substrates | \n", "
| 7 | \n", "AURKC | \n", "0.025000 | \n", "0.420000 | \n", "1 downregulated substrates | \n", "
| 8 | \n", "GRK4 | \n", "0.025000 | \n", "0.420000 | \n", "1 downregulated substrates | \n", "
| 9 | \n", "GSG2 | \n", "0.025000 | \n", "0.420000 | \n", "1 downregulated substrates | \n", "
| 10 | \n", "DAPK3 | \n", "0.046542 | \n", "0.525979 | \n", "2 downregulated substrates | \n", "
| 11 | \n", "TLK1 | \n", "0.049376 | \n", "0.525979 | \n", "1 downregulated substrates | \n", "
| 12 | \n", "ROCK1 | \n", "0.056355 | \n", "0.525979 | \n", "3 downregulated substrates | \n", "
| 13 | \n", "PRKCQ | \n", "0.056355 | \n", "0.525979 | \n", "3 downregulated substrates | \n", "
| 14 | \n", "ZAK | \n", "0.073144 | \n", "0.591983 | \n", "1 downregulated substrates | \n", "
| 15 | \n", "MARK1 | \n", "0.096319 | \n", "0.591983 | \n", "1 downregulated substrates | \n", "
| 16 | \n", "MAP4K1 | \n", "0.096319 | \n", "0.591983 | \n", "1 downregulated substrates | \n", "
| 17 | \n", "GRK7 | \n", "0.096319 | \n", "0.591983 | \n", "1 downregulated substrates | \n", "
| 18 | \n", "MATK | \n", "0.118916 | \n", "0.591983 | \n", "1 downregulated substrates | \n", "
| 19 | \n", "TGFBR1 | \n", "0.118916 | \n", "0.591983 | \n", "1 downregulated substrates | \n", "
| 20 | \n", "RPS6KA5 | \n", "0.128490 | \n", "0.591983 | \n", "2 downregulated substrates | \n", "
| 21 | \n", "MAPKAPK5 | \n", "0.140948 | \n", "0.591983 | \n", "1 downregulated substrates | \n", "
| 22 | \n", "GRK1 | \n", "0.140948 | \n", "0.591983 | \n", "1 downregulated substrates | \n", "
| 23 | \n", "KIT | \n", "0.140948 | \n", "0.591983 | \n", "1 downregulated substrates | \n", "
| 24 | \n", "GRK6 | \n", "0.140948 | \n", "0.591983 | \n", "1 downregulated substrates | \n", "
| 25 | \n", "VRK1 | \n", "0.162431 | \n", "0.593226 | \n", "1 downregulated substrates | \n", "
| 26 | \n", "PLK2 | \n", "0.162431 | \n", "0.593226 | \n", "1 downregulated substrates | \n", "
| 27 | \n", "WNK1 | \n", "0.162431 | \n", "0.593226 | \n", "1 downregulated substrates | \n", "
| 28 | \n", "BMPR1B | \n", "0.073144 | \n", "0.595603 | \n", "1 upregulated substrates | \n", "
| 29 | \n", "TXK | \n", "0.073144 | \n", "0.595603 | \n", "1 upregulated substrates | \n", "
| 30 | \n", "PIK3CG | \n", "0.073144 | \n", "0.595603 | \n", "1 upregulated substrates | \n", "
| 31 | \n", "CDK8 | \n", "0.096319 | \n", "0.610021 | \n", "1 upregulated substrates | \n", "
| 32 | \n", "BLK | \n", "0.096319 | \n", "0.610021 | \n", "1 upregulated substrates | \n", "
| 33 | \n", "FES | \n", "0.140948 | \n", "0.669504 | \n", "1 upregulated substrates | \n", "
| 34 | \n", "FGFR3 | \n", "0.162431 | \n", "0.712197 | \n", "1 upregulated substrates | \n", "
| 35 | \n", "MAPK4 | \n", "0.208510 | \n", "0.729786 | \n", "2 downregulated substrates | \n", "
| 36 | \n", "CDC42BPA | \n", "0.223715 | \n", "0.751683 | \n", "1 downregulated substrates | \n", "
| 37 | \n", "MELK | \n", "0.203801 | \n", "0.774445 | \n", "1 upregulated substrates | \n", "
| 38 | \n", "LRRK2 | \n", "0.203801 | \n", "0.774445 | \n", "1 upregulated substrates | \n", "
| 39 | \n", "MAP3K5 | \n", "0.243132 | \n", "0.785503 | \n", "1 downregulated substrates | \n", "
| 40 | \n", "CDK9 | \n", "0.243132 | \n", "0.799492 | \n", "1 upregulated substrates | \n", "
| 41 | \n", "ALK | \n", "0.243132 | \n", "0.799492 | \n", "1 upregulated substrates | \n", "
| 42 | \n", "HCK | \n", "0.273535 | \n", "0.799492 | \n", "2 upregulated substrates | \n", "
| 43 | \n", "PKN1 | \n", "0.280524 | \n", "0.799492 | \n", "1 upregulated substrates | \n", "
| 44 | \n", "ITK | \n", "0.280524 | \n", "0.799492 | \n", "1 upregulated substrates | \n", "
| 45 | \n", "PAK2 | \n", "0.316071 | \n", "0.857908 | \n", "1 upregulated substrates | \n", "
| 46 | \n", "FGFR1 | \n", "0.349866 | \n", "0.903140 | \n", "1 upregulated substrates | \n", "
| 47 | \n", "IGF1R | \n", "0.364425 | \n", "0.903140 | \n", "3 upregulated substrates | \n", "
| 48 | \n", "PAK1 | \n", "0.338354 | \n", "0.961256 | \n", "2 downregulated substrates | \n", "
| 49 | \n", "PLK3 | \n", "0.366133 | \n", "0.961256 | \n", "1 downregulated substrates | \n", "
| 50 | \n", "PIM1 | \n", "0.366133 | \n", "0.961256 | \n", "1 downregulated substrates | \n", "
| Rank | \n", "Kinase | \n", "P-value | \n", "FDR | \n", "Substrate | \n", "
|---|---|---|---|---|
| 1 | \n", "IRAK2 | \n", "0.003686 | \n", "0.999513 | \n", "16 downregulated substrates | \n", "
| 2 | \n", "DCLK2 | \n", "0.008592 | \n", "0.999513 | \n", "15 upregulated substrates | \n", "
| 3 | \n", "KDR | \n", "0.008592 | \n", "0.999513 | \n", "15 upregulated substrates | \n", "
| 4 | \n", "RIPK2 | \n", "0.008592 | \n", "0.999513 | \n", "15 downregulated substrates | \n", "
| 5 | \n", "CDK11A | \n", "0.018802 | \n", "0.999513 | \n", "14 upregulated substrates | \n", "
| 6 | \n", "STK32C | \n", "0.018802 | \n", "0.999513 | \n", "14 upregulated substrates | \n", "
| 7 | \n", "TSSK1B | \n", "0.018802 | \n", "0.999513 | \n", "14 upregulated substrates | \n", "
| 8 | \n", "DYRK4 | \n", "0.018802 | \n", "0.999513 | \n", "14 upregulated substrates | \n", "
| 9 | \n", "AURKC | \n", "0.018802 | \n", "0.999513 | \n", "14 downregulated substrates | \n", "
| 10 | \n", "PRKACB | \n", "0.018802 | \n", "0.999513 | \n", "14 downregulated substrates | \n", "
| 11 | \n", "TSSK6 | \n", "0.038521 | \n", "0.999513 | \n", "13 upregulated substrates | \n", "
| 12 | \n", "NRBP1 | \n", "0.038521 | \n", "0.999513 | \n", "13 upregulated substrates | \n", "
| 13 | \n", "MAP3K9 | \n", "0.038521 | \n", "0.999513 | \n", "13 upregulated substrates | \n", "
| 14 | \n", "TRIB2 | \n", "0.038521 | \n", "0.999513 | \n", "13 upregulated substrates | \n", "
| 15 | \n", "PDK4 | \n", "0.038521 | \n", "0.999513 | \n", "13 upregulated substrates | \n", "
| 16 | \n", "ALK | \n", "0.038521 | \n", "0.999513 | \n", "13 upregulated substrates | \n", "
| 17 | \n", "STK32B | \n", "0.038521 | \n", "0.999513 | \n", "13 downregulated substrates | \n", "
| 18 | \n", "MYLK4 | \n", "0.038521 | \n", "0.999513 | \n", "13 downregulated substrates | \n", "
| 19 | \n", "MAP3K8 | \n", "0.038521 | \n", "0.999513 | \n", "13 downregulated substrates | \n", "
| 20 | \n", "ALPK2 | \n", "0.038521 | \n", "0.999513 | \n", "13 downregulated substrates | \n", "
| 21 | \n", "DDR2 | \n", "0.038521 | \n", "0.999513 | \n", "13 downregulated substrates | \n", "
| 22 | \n", "RIPK4 | \n", "0.038521 | \n", "0.999513 | \n", "13 downregulated substrates | \n", "
| 23 | \n", "CLK3 | \n", "0.073688 | \n", "0.999513 | \n", "12 upregulated substrates | \n", "
| 24 | \n", "TSSK2 | \n", "0.073688 | \n", "0.999513 | \n", "12 upregulated substrates | \n", "
| 25 | \n", "INSRR | \n", "0.073688 | \n", "0.999513 | \n", "12 upregulated substrates | \n", "
| 26 | \n", "TSSK3 | \n", "0.073688 | \n", "0.999513 | \n", "12 upregulated substrates | \n", "
| 27 | \n", "CDK19 | \n", "0.073688 | \n", "0.999513 | \n", "12 upregulated substrates | \n", "
| 28 | \n", "SRPK2 | \n", "0.073688 | \n", "0.999513 | \n", "12 upregulated substrates | \n", "
| 29 | \n", "NTRK2 | \n", "0.073688 | \n", "0.999513 | \n", "12 upregulated substrates | \n", "
| 30 | \n", "CDK15 | \n", "0.073688 | \n", "0.999513 | \n", "12 downregulated substrates | \n", "
| 31 | \n", "MUSK | \n", "0.073688 | \n", "0.999513 | \n", "12 downregulated substrates | \n", "
| 32 | \n", "BMX | \n", "0.073688 | \n", "0.999513 | \n", "12 downregulated substrates | \n", "
| 33 | \n", "CDK14 | \n", "0.073688 | \n", "0.999513 | \n", "12 downregulated substrates | \n", "
| 34 | \n", "SRPK3 | \n", "0.073688 | \n", "0.999513 | \n", "12 downregulated substrates | \n", "
| 35 | \n", "PRKG1 | \n", "0.073688 | \n", "0.999513 | \n", "12 downregulated substrates | \n", "
| 36 | \n", "STYK1 | \n", "0.073688 | \n", "0.999513 | \n", "12 downregulated substrates | \n", "
| 37 | \n", "PRKAA2 | \n", "0.073688 | \n", "0.999513 | \n", "12 downregulated substrates | \n", "
| 38 | \n", "SRC | \n", "0.073688 | \n", "0.999513 | \n", "12 downregulated substrates | \n", "
| 39 | \n", "SBK2 | \n", "0.131261 | \n", "0.999513 | \n", "11 upregulated substrates | \n", "
| 40 | \n", "PAK6 | \n", "0.131261 | \n", "0.999513 | \n", "11 upregulated substrates | \n", "
| 41 | \n", "MAPK10 | \n", "0.131261 | \n", "0.999513 | \n", "11 upregulated substrates | \n", "
| 42 | \n", "NTRK3 | \n", "0.131261 | \n", "0.999513 | \n", "11 upregulated substrates | \n", "
| 43 | \n", "KALRN | \n", "0.131261 | \n", "0.999513 | \n", "11 upregulated substrates | \n", "
| 44 | \n", "HIPK4 | \n", "0.131261 | \n", "0.999513 | \n", "11 downregulated substrates | \n", "
| 45 | \n", "DYRK1B | \n", "0.131261 | \n", "0.999513 | \n", "11 downregulated substrates | \n", "
| 46 | \n", "EPHB2 | \n", "0.131261 | \n", "0.999513 | \n", "11 downregulated substrates | \n", "
| 47 | \n", "PLK5 | \n", "0.131261 | \n", "0.999513 | \n", "11 downregulated substrates | \n", "
| 48 | \n", "DMPK | \n", "0.131261 | \n", "0.999513 | \n", "11 downregulated substrates | \n", "
| 49 | \n", "FLT1 | \n", "0.131261 | \n", "0.999513 | \n", "11 downregulated substrates | \n", "
| 50 | \n", "MAP2K4 | \n", "0.131261 | \n", "0.999513 | \n", "11 downregulated substrates | \n", "
| Rank | \n", "miRNA | \n", "P-value | \n", "FDR | \n", "Target | \n", "
|---|---|---|---|---|
| 1 | \n", "mmu-miR-450a | \n", "0.040580 | \n", "1.0 | \n", "11 upregulated targets | \n", "
| 2 | \n", "mmu-miR-5122 | \n", "0.062147 | \n", "1.0 | \n", "6 upregulated targets | \n", "
| 3 | \n", "hsa-miR-1181 | \n", "0.134089 | \n", "1.0 | \n", "5 upregulated targets | \n", "
| 4 | \n", "mmu-miR-718 | \n", "0.264980 | \n", "1.0 | \n", "9 upregulated targets | \n", "
| 5 | \n", "hsa-miR-4321 | \n", "0.265392 | \n", "1.0 | \n", "7 upregulated targets | \n", "
| 6 | \n", "mmu-miR-700 | \n", "0.290455 | \n", "1.0 | \n", "4 upregulated targets | \n", "
| 7 | \n", "mmu-miR-5136 | \n", "0.308628 | \n", "1.0 | \n", "6 upregulated targets | \n", "
| 8 | \n", "mmu-miR-1965 | \n", "0.309172 | \n", "1.0 | \n", "15 upregulated targets | \n", "
| 9 | \n", "hsa-miR-523 | \n", "0.378061 | \n", "1.0 | \n", "3 upregulated targets | \n", "
| 10 | \n", "hsa-miR-1282 | \n", "0.387502 | \n", "1.0 | \n", "14 upregulated targets | \n", "
| 11 | \n", "mmu-miR-1843b-3p | \n", "0.401321 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 12 | \n", "hsa-miR-1180 | \n", "0.426919 | \n", "1.0 | \n", "13 upregulated targets | \n", "
| 13 | \n", "hsa-miR-4664-3p | \n", "0.442075 | \n", "1.0 | \n", "12 upregulated targets | \n", "
| 14 | \n", "mmu-miR-3960 | \n", "0.455096 | \n", "1.0 | \n", "6 upregulated targets | \n", "
| 15 | \n", "mmu-miR-341 | \n", "0.469615 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 16 | \n", "hsa-miR-3193 | \n", "0.473085 | \n", "1.0 | \n", "18 upregulated targets | \n", "
| 17 | \n", "hsa-miR-1468 | \n", "0.481784 | \n", "1.0 | \n", "16 upregulated targets | \n", "
| 18 | \n", "hsa-miR-524-3p | \n", "0.493676 | \n", "1.0 | \n", "12 upregulated targets | \n", "
| 19 | \n", "hsa-miR-525-3p | \n", "0.493676 | \n", "1.0 | \n", "12 upregulated targets | \n", "
| 20 | \n", "hsa-miR-4781-5p | \n", "0.498074 | \n", "1.0 | \n", "21 upregulated targets | \n", "
| 21 | \n", "mmu-miR-337-5p | \n", "0.516989 | \n", "1.0 | \n", "5 upregulated targets | \n", "
| 22 | \n", "hsa-miR-324-5p | \n", "0.525676 | \n", "1.0 | \n", "49 upregulated targets | \n", "
| 23 | \n", "hsa-miR-602 | \n", "0.531322 | \n", "1.0 | \n", "22 upregulated targets | \n", "
| 24 | \n", "hsa-miR-4665-3p | \n", "0.533681 | \n", "1.0 | \n", "9 upregulated targets | \n", "
| 25 | \n", "hsa-miR-3678-5p | \n", "0.540848 | \n", "1.0 | \n", "6 upregulated targets | \n", "
| 26 | \n", "hsa-miR-4787-3p | \n", "0.563885 | \n", "1.0 | \n", "9 upregulated targets | \n", "
| 27 | \n", "mmu-miR-3081 | \n", "0.574530 | \n", "1.0 | \n", "8 upregulated targets | \n", "
| 28 | \n", "mmu-miR-3080-3p | \n", "0.578343 | \n", "1.0 | \n", "21 upregulated targets | \n", "
| 29 | \n", "hsa-miR-1469 | \n", "0.580314 | \n", "1.0 | \n", "3 upregulated targets | \n", "
| 30 | \n", "mmu-miR-1b-3p | \n", "0.585492 | \n", "1.0 | \n", "36 upregulated targets | \n", "
| 31 | \n", "hsa-miR-4798-5p | \n", "0.586756 | \n", "1.0 | \n", "7 upregulated targets | \n", "
| 32 | \n", "mmu-miR-3080-5p | \n", "0.590776 | \n", "1.0 | \n", "11 upregulated targets | \n", "
| 33 | \n", "mmu-miR-5115 | \n", "0.595127 | \n", "1.0 | \n", "8 upregulated targets | \n", "
| 34 | \n", "hsa-miR-3683 | \n", "0.595127 | \n", "1.0 | \n", "8 upregulated targets | \n", "
| 35 | \n", "mmu-miR-296-3p | \n", "0.598757 | \n", "1.0 | \n", "39 upregulated targets | \n", "
| 36 | \n", "mmu-miR-675-5p | \n", "0.600950 | \n", "1.0 | \n", "10 upregulated targets | \n", "
| 37 | \n", "hsa-miR-4783-3p | \n", "0.608754 | \n", "1.0 | \n", "15 upregulated targets | \n", "
| 38 | \n", "mmu-miR-293 | \n", "0.618533 | \n", "1.0 | \n", "9 upregulated targets | \n", "
| 39 | \n", "mmu-miR-666-5p | \n", "0.625703 | \n", "1.0 | \n", "12 upregulated targets | \n", "
| 40 | \n", "hsa-miR-127-3p | \n", "0.642471 | \n", "1.0 | \n", "6 upregulated targets | \n", "
| 41 | \n", "hsa-miR-4783-5p | \n", "0.642471 | \n", "1.0 | \n", "6 upregulated targets | \n", "
| 42 | \n", "hsa-miR-3181 | \n", "0.644486 | \n", "1.0 | \n", "11 upregulated targets | \n", "
| 43 | \n", "mmu-miR-3970 | \n", "0.647263 | \n", "1.0 | \n", "30 upregulated targets | \n", "
| 44 | \n", "mmu-miR-1901 | \n", "0.649778 | \n", "1.0 | \n", "3 upregulated targets | \n", "
| 45 | \n", "hsa-miR-4497 | \n", "0.654339 | \n", "1.0 | \n", "15 upregulated targets | \n", "
| 46 | \n", "hsa-miR-4655-3p | \n", "0.661278 | \n", "1.0 | \n", "15 upregulated targets | \n", "
| 47 | \n", "mmu-miR-3104-3p | \n", "0.668486 | \n", "1.0 | \n", "14 upregulated targets | \n", "
| 48 | \n", "hsa-miR-4671-5p | \n", "0.671490 | \n", "1.0 | \n", "13 upregulated targets | \n", "
| 49 | \n", "mmu-miR-711 | \n", "0.688772 | \n", "1.0 | \n", "23 upregulated targets | \n", "
| 50 | \n", "mmu-miR-1945 | \n", "0.698909 | \n", "1.0 | \n", "4 upregulated targets | \n", "
| Rank | \n", "miRNA | \n", "P-value | \n", "FDR | \n", "Target | \n", "
|---|---|---|---|---|
| 1 | \n", "mmu-miR-3089-3p | \n", "0.008753 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 2 | \n", "mmu-miR-99b-5p | \n", "0.008753 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 3 | \n", "hsa-miR-4670-5p | \n", "0.015805 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 4 | \n", "mmu-miR-148a-3p | \n", "0.052463 | \n", "1.0 | \n", "3 upregulated targets | \n", "
| 5 | \n", "mmu-miR-146b-5p | \n", "0.052833 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 6 | \n", "mmu-miR-344f-5p | \n", "0.052833 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 7 | \n", "mmu-miR-1929-5p | \n", "0.073324 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 8 | \n", "mmu-miR-3105-3p | \n", "0.080637 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 9 | \n", "mmu-miR-31-5p | \n", "0.095887 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 10 | \n", "mmu-miR-713 | \n", "0.095887 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 11 | \n", "hsa-miR-645 | \n", "0.097058 | \n", "1.0 | \n", "3 upregulated targets | \n", "
| 12 | \n", "mmu-miR-325-3p | \n", "0.103796 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 13 | \n", "hsa-miR-4326 | \n", "0.105894 | \n", "1.0 | \n", "4 upregulated targets | \n", "
| 14 | \n", "hsa-miR-4733-3p | \n", "0.116010 | \n", "1.0 | \n", "5 upregulated targets | \n", "
| 15 | \n", "hsa-miR-3177-5p | \n", "0.118270 | \n", "1.0 | \n", "4 upregulated targets | \n", "
| 16 | \n", "hsa-miR-2114-3p | \n", "0.118270 | \n", "1.0 | \n", "4 upregulated targets | \n", "
| 17 | \n", "mmu-miR-134-5p | \n", "0.120110 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 18 | \n", "mmu-miR-29b-3p | \n", "0.134838 | \n", "1.0 | \n", "3 upregulated targets | \n", "
| 19 | \n", "mmu-miR-704 | \n", "0.140948 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 20 | \n", "hsa-miR-4686 | \n", "0.152363 | \n", "1.0 | \n", "3 upregulated targets | \n", "
| 21 | \n", "hsa-miR-5004-3p | \n", "0.152363 | \n", "1.0 | \n", "3 upregulated targets | \n", "
| 22 | \n", "mmu-miR-148b-3p | \n", "0.154370 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 23 | \n", "mmu-miR-152-3p | \n", "0.154370 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 24 | \n", "hsa-miR-33a-3p | \n", "0.159705 | \n", "1.0 | \n", "6 upregulated targets | \n", "
| 25 | \n", "mmu-miR-217-5p | \n", "0.162431 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 26 | \n", "mmu-miR-192-5p | \n", "0.162431 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 27 | \n", "mmu-miR-3088-3p | \n", "0.162431 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 28 | \n", "mmu-miR-5046 | \n", "0.162431 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 29 | \n", "mmu-miR-770-5p | \n", "0.162431 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 30 | \n", "mmu-miR-540-3p | \n", "0.162431 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 31 | \n", "mmu-miR-767 | \n", "0.162431 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 32 | \n", "mmu-miR-380-5p | \n", "0.162431 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 33 | \n", "mmu-miR-615-5p | \n", "0.162431 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 34 | \n", "hsa-miR-3119 | \n", "0.163599 | \n", "1.0 | \n", "4 upregulated targets | \n", "
| 35 | \n", "mmu-miR-3971 | \n", "0.181133 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 36 | \n", "hsa-miR-1185-2-3p | \n", "0.182066 | \n", "1.0 | \n", "5 upregulated targets | \n", "
| 37 | \n", "hsa-miR-2277-3p | \n", "0.183019 | \n", "1.0 | \n", "3 upregulated targets | \n", "
| 38 | \n", "mmu-miR-2183 | \n", "0.183378 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 39 | \n", "hsa-miR-4664-3p | \n", "0.183378 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 40 | \n", "mmu-miR-3093-3p | \n", "0.183378 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 41 | \n", "mmu-miR-215-5p | \n", "0.183378 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 42 | \n", "mmu-miR-3101-5p | \n", "0.183378 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 43 | \n", "mmu-miR-342-5p | \n", "0.183378 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 44 | \n", "mmu-miR-434-3p | \n", "0.190202 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 45 | \n", "mmu-miR-146a-5p | \n", "0.199331 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 46 | \n", "hsa-miR-4277 | \n", "0.202136 | \n", "1.0 | \n", "3 upregulated targets | \n", "
| 47 | \n", "mmu-miR-206-3p | \n", "0.208510 | \n", "1.0 | \n", "2 upregulated targets | \n", "
| 48 | \n", "hsa-miR-4804-3p | \n", "0.215130 | \n", "1.0 | \n", "3 upregulated targets | \n", "
| 49 | \n", "mmu-miR-582-3p | \n", "0.223715 | \n", "1.0 | \n", "1 upregulated targets | \n", "
| 50 | \n", "mmu-miR-743b-5p | \n", "0.223715 | \n", "1.0 | \n", "1 upregulated targets | \n", "