DMS ID,Site-Independent,EVmutation,DeepSequence (single),DeepSequence (ensemble),EVE (single),EVE (ensemble),Unirep,Unirep evotuned,MSA Transformer (single),MSA Transformer (ensemble),ESM-1b,ESM-1v (single),ESM-1v (ensemble),ESM2 (8M),ESM2 (35M),ESM2 (150M),ESM2 (650M),ESM2 (3B),ESM2 (15B),Wavenet,RITA S,RITA M,RITA L,RITA XL,Progen2 S,Progen2 M,Progen2 Base,Progen2 L,Progen2 XL,GEMME,VESPA,VESPAl,VespaG,ProtGPT2,Tranception S no retrieval,Tranception M no retrieval,Tranception L no retrieval,Tranception S,Tranception M,Tranception L,TranceptEVE S,TranceptEVE M,TranceptEVE L,CARP (38M),CARP (600K),CARP (640M),CARP (76M),MIF,MIF-ST,ESM-IF1,ProteinMPNN,"ProtSSN (k=10, h=512)","ProtSSN (k=10, h=768)","ProtSSN (k=10, h=1280)","ProtSSN (k=20, h=512)","ProtSSN (k=20, h=768)","ProtSSN (k=20, h=1280)","ProtSSN (k=30, h=512)","ProtSSN (k=30, h=768)","ProtSSN (k=30, h=1280)",ProtSSN (ensemble),SaProt (650M),SaProt (35M),PoET (200M),MULAN,ProSST (K=20),ProSST (K=128),ProSST (K=512),ProSST (K=1024),ProSST (K=2048),ProSST (K=4096),ESCOTT,VenusREM,RSALOR,S2F,S2F-MSA,S3F,S3F-MSA,SiteRM,ESM3 open (1.4B),ESM-C (300M),ESM-C (600M),xTrimoPGLM-1B-MLM,xTrimoPGLM-3B-MLM,xTrimoPGLM-10B-MLM,xTrimoPGLM-1B-CLM,xTrimoPGLM-3B-CLM,xTrimoPGLM-7B-CLM,xTrimoPGLM-100B-int4,Progen3 112m,Progen3 219m,Progen3 339m,Progen3 762m,Progen3 1B,Progen3 3B,AIDO Protein-RAG (16B),Protriever,Number of Mutants,Selection Type,UniProt ID,MSA_Neff_L_category,Taxon
A0A140D2T1_ZIKV_Sourisseau_2019,0.383,0.354,0.131,0.103,0.394,0.405,-0.133,0.062,0.436,0.439,-0.001,-0.048,0.015,-0.073,-0.054,-0.058,0.213,0.363,0.375,0.216,0.361,0.309,0.317,0.305,0.329,0.342,0.328,0.312,0.293,0.43,0.319,0.296,0.38,0.005,0.304,0.331,0.272,0.362,0.366,0.351,0.361,0.358,0.373,-0.06,-0.073,0.131,-0.061,0.273,0.29,0.287,0.129,0.253,0.251,0.282,0.296,0.277,0.269,0.263,0.269,0.265,0.278,0.199,0.116,0.429,0.071,0.107,0.102,0.113,0.113,0.28,0.112,0.471,0.387,0.423,0.285,0.402,0.308,0.418,0.415,0.277,-0.058,-0.048,-0.048,0.366,0.373,0.332,0.282,-0.024,0.303,0.032,0.191,0.305,0.298,0.354,0.338,0.427,0.477,9576,OrganismalFitness,A0A140D2T1_ZIKV,Medium,Virus
A0A192B1T2_9HIV1_Haddox_2018,0.481,0.407,0.413,0.432,0.509,0.516,0.0,0.513,0.511,0.515,0.456,0.492,0.516,-0.003,0.015,0.035,0.08,0.132,0.164,0.465,0.496,0.507,0.509,0.505,0.497,0.501,0.463,0.49,0.484,0.496,0.541,0.507,0.299,0.327,0.492,0.483,0.514,0.509,0.503,0.513,0.524,0.518,0.528,0.422,-0.021,0.497,0.429,0.329,0.451,0.206,0.136,0.202,0.23,0.258,0.263,0.21,0.226,0.228,0.2,0.183,0.239,0.173,0.084,0.488,0.051,0.341,0.383,0.382,0.404,0.447,0.419,0.522,0.562,0.532,0.307,0.523,0.365,0.552,0.515,0.257,0.478,0.46,0.488,0.521,0.466,0.476,0.332,0.024,0.334,0.409,0.482,0.471,0.473,0.487,0.499,0.595,0.504,12577,OrganismalFitness,A0A192B1T2_9HIV1,Medium,Virus
A0A1I9GEU1_NEIME_Kennouche_2019,-0.011,0.044,0.107,0.098,0.053,0.054,-0.024,0.084,0.082,0.077,0.04,0.068,0.068,-0.037,-0.047,-0.016,0.03,0.027,0.025,0.067,-0.01,0.047,0.071,0.088,0.05,0.088,0.08,0.089,0.095,0.045,0.046,0.036,0.033,0.03,0.036,0.055,0.099,0.031,0.041,0.057,0.058,0.061,0.075,-0.055,-0.056,0.039,-0.043,0.051,0.055,0.039,0.04,0.054,0.042,0.039,0.035,0.037,0.052,0.039,0.058,0.041,0.047,0.04,-0.005,0.057,-0.016,0.146,0.177,0.199,0.176,0.076,0.182,0.041,0.07,-0.01,0.043,0.055,0.049,0.058,0.061,0.025,0.058,0.051,0.042,0.051,0.053,0.061,0.02,0.037,0.065,-0.019,0.008,0.043,0.059,0.088,0.094,0.064,0.056,922,Activity,A0A1I9GEU1_NEIME,Medium,Prokaryote
A0A247D711_LISMN_Stadelmann_2021,0.436,0.459,0.109,0.041,0.428,0.428,0.003,0.026,0.299,0.32,0.087,0.088,0.093,0.064,0.084,0.097,0.066,0.084,0.084,0.059,0.021,0.015,0.04,0.078,-0.029,0.067,0.01,0.037,0.106,0.473,0.337,0.351,0.382,0.093,0.041,0.024,0.057,0.301,0.292,0.311,0.253,0.242,0.263,0.047,0.002,0.074,0.084,0.418,0.441,0.476,0.364,0.274,0.326,0.314,0.344,0.313,0.36,0.312,0.331,0.265,0.335,0.427,0.28,0.458,0.162,0.45,0.476,0.507,0.553,0.509,0.544,0.529,0.556,0.481,0.355,0.493,0.4,0.512,0.449,0.451,0.096,0.113,0.076,0.063,0.085,-0.028,-0.12,0.004,0.14,0.047,0.076,0.049,0.054,0.07,0.107,0.524,0.531,1653,Activity,A0A247D711_LISMN,Low,Prokaryote
A0A2Z5U3Z0_9INFA_Doud_2016,0.478,0.473,0.484,0.517,0.545,0.548,0.009,0.492,0.495,0.496,0.124,0.516,0.55,-0.004,0.013,0.064,0.507,0.498,0.501,0.413,0.467,0.534,0.52,0.542,0.433,0.52,0.513,0.494,0.504,0.538,0.49,0.4,0.563,0.076,0.47,0.525,0.523,0.518,0.548,0.537,0.557,0.576,0.573,0.006,0.0,0.339,0.017,0.43,0.487,0.462,0.174,0.489,0.474,0.529,0.522,0.526,0.524,0.535,0.516,0.545,0.537,0.199,0.152,0.545,0.13,0.327,0.324,0.356,0.386,0.483,0.374,0.583,0.557,0.562,0.518,0.59,0.554,0.611,0.548,0.406,0.046,0.055,0.095,0.497,0.492,0.42,0.322,0.024,0.483,0.441,0.466,0.488,0.501,0.534,0.527,0.616,0.527,10715,OrganismalFitness,A0A2Z5U3Z0_9INFA,Medium,Virus
A0A2Z5U3Z0_9INFA_Wu_2014,0.48,0.506,0.454,0.478,0.506,0.521,0.021,0.436,0.495,0.509,0.155,0.461,0.509,0.048,0.073,0.073,0.464,0.481,0.485,0.458,0.45,0.503,0.484,0.511,0.345,0.46,0.482,0.447,0.475,0.513,0.442,0.375,0.488,0.085,0.442,0.493,0.519,0.506,0.534,0.541,0.541,0.556,0.558,0.052,0.051,0.253,0.069,0.355,0.38,0.362,0.147,0.432,0.429,0.455,0.451,0.454,0.461,0.468,0.449,0.462,0.468,0.229,0.197,0.528,0.189,0.307,0.31,0.344,0.361,0.37,0.358,0.53,0.438,0.466,0.448,0.536,0.462,0.544,0.53,0.35,0.09,0.086,0.122,0.466,0.465,0.356,0.293,0.027,0.475,0.425,0.435,0.461,0.45,0.492,0.482,0.512,0.538,2350,OrganismalFitness,A0A2Z5U3Z0_9INFA,Medium,Virus
A4_HUMAN_Seuma_2022,0.394,0.385,0.449,0.425,0.312,0.316,0.345,0.167,0.337,0.351,0.302,0.316,0.404,0.382,0.366,0.372,0.431,0.48,0.352,0.261,0.327,0.281,0.318,0.306,0.406,0.297,0.32,0.313,0.314,0.478,0.251,0.186,0.487,0.487,0.393,0.273,0.37,0.441,0.372,0.458,0.436,0.4,0.416,0.366,0.362,0.421,0.356,0.279,0.358,-0.191,0.06,0.449,0.44,0.417,0.41,0.406,0.38,0.423,0.346,0.372,0.417,0.411,0.388,0.407,0.388,0.373,0.407,0.401,0.327,0.433,0.334,0.5,0.423,0.388,0.427,0.429,0.444,0.441,0.433,0.377,0.517,0.471,0.317,0.305,0.369,0.26,0.248,0.116,0.291,0.345,0.38,0.375,0.35,0.333,0.35,0.412,0.442,14811,Stability,A4_HUMAN,Low,Human
A4D664_9INFA_Soh_2019,0.411,0.34,0.406,0.403,0.409,0.408,0.029,0.364,0.297,0.287,0.044,0.026,0.033,0.022,0.02,0.027,0.149,0.211,0.27,0.26,0.329,0.386,0.404,0.398,0.064,0.26,0.285,0.244,0.33,0.443,0.318,0.296,0.266,0.055,0.348,0.371,0.404,0.366,0.38,0.393,0.434,0.439,0.461,0.019,-0.0,0.08,-0.001,0.262,0.254,0.126,0.105,0.183,0.18,0.191,0.216,0.209,0.207,0.2,0.198,0.193,0.204,0.148,0.092,0.353,0.076,0.184,0.194,0.204,0.227,0.296,0.233,0.442,0.318,0.322,0.218,0.404,0.22,0.41,0.472,0.271,0.028,0.04,0.022,0.042,0.183,0.261,0.214,-0.003,0.102,0.337,0.349,0.352,0.362,0.39,0.38,0.363,0.344,14421,OrganismalFitness,A4D664_9INFA,Medium,Virus
A4GRB6_PSEAI_Chen_2020,0.317,0.492,0.657,0.664,0.623,0.641,0.344,0.529,0.641,0.681,0.68,0.647,0.668,0.431,0.528,0.655,0.738,0.712,0.627,0.567,0.409,0.533,0.564,0.624,0.526,0.622,0.639,0.638,0.705,0.671,0.742,0.673,0.706,0.242,0.423,0.552,0.629,0.557,0.588,0.652,0.653,0.66,0.679,0.481,0.071,0.671,0.601,0.664,0.713,0.629,0.422,0.728,0.718,0.711,0.719,0.729,0.733,0.728,0.733,0.735,0.745,0.722,0.513,0.737,0.331,0.558,0.619,0.627,0.661,0.65,0.642,0.733,0.66,0.718,0.743,0.736,0.746,0.739,0.615,0.65,0.68,0.716,0.649,0.703,0.696,0.572,0.402,0.103,0.722,0.447,0.52,0.591,0.59,0.62,0.632,0.758,0.705,5004,OrganismalFitness,A4GRB6_PSEAI,High,Prokaryote
AACC1_PSEAI_Dandage_2018,0.282,0.474,0.331,0.414,0.487,0.491,0.196,0.191,0.501,0.504,0.413,0.483,0.489,0.196,0.248,0.256,0.49,0.511,0.518,0.391,0.206,0.232,0.276,0.306,0.273,0.428,0.407,0.413,0.438,0.465,0.507,0.455,0.481,0.021,0.259,0.246,0.417,0.427,0.418,0.466,0.471,0.466,0.495,0.216,0.17,0.354,0.243,0.257,0.374,0.357,0.183,0.481,0.492,0.483,0.488,0.495,0.486,0.486,0.477,0.494,0.5,0.461,0.282,0.515,0.259,0.363,0.431,0.454,0.44,0.372,0.418,0.503,0.36,0.491,0.524,0.543,0.525,0.541,0.344,0.52,0.519,0.498,0.493,0.527,0.502,0.382,0.239,0.102,0.515,0.247,0.34,0.405,0.45,0.462,0.464,0.491,0.518,1801,OrganismalFitness,AACC1_PSEAI,High,Prokaryote
ACE2_HUMAN_Chan_2020,0.254,0.237,0.187,0.2,0.249,0.242,-0.049,0.077,0.236,0.251,0.244,0.173,0.213,-0.053,0.062,0.216,0.225,0.175,0.178,0.227,0.033,0.129,0.175,0.207,0.042,0.162,0.207,0.208,0.261,0.217,0.164,0.138,0.19,0.08,0.044,0.12,0.134,0.217,0.19,0.196,0.228,0.2,0.205,0.005,0.005,0.244,0.078,0.336,0.292,0.317,0.106,0.217,0.255,0.226,0.222,0.236,0.249,0.223,0.221,0.214,0.234,0.289,0.168,0.23,0.037,0.189,0.185,0.279,0.269,0.225,0.227,0.243,0.253,0.181,0.227,0.256,0.242,0.267,0.236,0.334,0.233,0.284,0.187,0.202,0.196,0.207,0.14,0.032,0.185,0.072,0.076,0.106,0.145,0.211,0.239,0.267,0.23,2223,Binding,ACE2_HUMAN,Medium,Human
ADRB2_HUMAN_Jones_2020,0.331,0.423,0.506,0.514,0.497,0.517,0.463,0.5,0.531,0.53,0.534,0.526,0.539,0.408,0.444,0.474,0.493,0.505,0.515,0.521,0.509,0.524,0.517,0.493,0.524,0.531,0.538,0.533,0.502,0.545,0.5,0.414,0.527,0.298,0.528,0.53,0.506,0.528,0.541,0.533,0.533,0.538,0.537,0.471,0.181,0.528,0.51,0.419,0.477,0.451,0.223,0.486,0.486,0.5,0.508,0.501,0.498,0.493,0.506,0.494,0.509,0.554,0.516,0.538,0.511,0.367,0.414,0.409,0.405,0.521,0.426,0.547,0.526,0.488,0.514,0.543,0.513,0.544,0.477,0.497,0.54,0.549,0.526,0.527,0.511,0.487,0.478,0.219,0.482,0.452,0.505,0.52,0.533,0.527,0.522,0.562,0.547,7800,Activity,ADRB2_HUMAN,Medium,Human
AICDA_HUMAN_Gajula_2014_3cycles,0.138,0.396,0.474,0.464,0.429,0.445,-0.287,0.327,0.32,0.385,0.415,0.376,0.478,-0.245,-0.264,0.196,0.328,0.347,0.262,0.479,-0.219,0.14,0.388,0.395,0.013,0.321,0.417,0.413,0.282,0.376,0.45,0.405,0.467,0.057,-0.039,0.057,0.339,0.206,0.218,0.367,0.399,0.402,0.444,-0.228,-0.238,0.379,0.258,0.328,0.401,0.328,0.243,0.337,0.404,0.344,0.447,0.359,0.365,0.341,0.343,0.312,0.359,0.257,-0.036,0.478,0.114,0.406,0.247,0.265,0.263,0.388,0.479,0.405,0.399,0.395,0.326,0.433,0.363,0.446,0.327,0.333,0.288,0.278,0.296,0.369,0.349,0.346,0.109,0.035,0.347,-0.242,-0.224,-0.226,-0.216,0.339,0.367,0.431,0.446,209,Activity,AICDA_HUMAN,Medium,Human
AMFR_HUMAN_Tsuboyama_2023_4G3O,0.358,0.418,0.419,0.407,0.386,0.398,-0.301,0.13,0.22,0.24,0.374,0.07,0.423,-0.209,0.286,0.321,0.261,0.297,0.26,0.062,-0.052,-0.218,-0.051,-0.038,-0.317,-0.089,-0.05,-0.121,0.056,0.396,0.254,0.228,0.289,0.09,-0.287,-0.139,-0.275,0.392,0.402,0.356,0.424,0.422,0.374,-0.185,-0.194,0.165,0.114,0.251,0.112,0.433,0.353,0.446,0.326,0.204,0.349,0.342,0.349,0.343,0.339,0.361,0.343,0.347,0.397,0.272,0.09,0.363,0.418,0.479,0.535,0.481,0.587,0.41,0.496,0.341,0.328,0.367,0.322,0.362,0.251,0.29,0.364,0.262,0.205,0.247,0.253,-0.064,-0.224,-0.144,0.262,-0.257,-0.164,-0.253,-0.209,-0.153,-0.133,0.445,0.355,2972,Stability,AMFR_HUMAN,Medium,Human
AMIE_PSEAE_Wrenbeck_2017,0.246,0.443,0.496,0.506,0.477,0.464,0.093,0.436,0.401,0.605,0.57,0.613,0.662,0.326,0.408,0.428,0.557,0.674,0.613,0.506,0.555,0.525,0.532,0.542,0.566,0.561,0.534,0.559,0.508,0.558,0.583,0.528,0.66,0.265,0.601,0.47,0.405,0.585,0.479,0.438,0.58,0.506,0.481,0.356,0.096,0.483,0.412,0.368,0.469,0.407,0.213,0.555,0.519,0.53,0.537,0.529,0.541,0.523,0.54,0.564,0.556,0.607,0.41,0.648,0.531,0.381,0.394,0.389,0.427,0.486,0.439,0.626,0.505,0.582,0.559,0.589,0.547,0.584,0.524,0.473,0.455,0.502,0.671,0.622,0.647,0.518,0.456,0.159,0.562,0.607,0.516,0.512,0.528,0.456,0.422,0.671,0.671,6227,Activity,AMIE_PSEAE,Medium,Prokaryote
ANCSZ_Hobbs_2022,0.562,0.521,0.445,0.472,0.524,0.528,0.525,0.452,0.503,0.524,0.527,0.522,0.543,0.535,0.592,0.598,0.609,0.598,0.57,0.021,0.462,0.493,0.509,0.5,0.497,0.519,0.513,0.469,0.494,0.557,0.542,0.525,0.56,0.318,0.483,0.503,0.475,0.537,0.549,0.538,0.545,0.556,0.543,0.549,0.42,0.496,0.523,0.471,0.458,0.422,0.165,0.566,0.555,0.572,0.578,0.572,0.584,0.569,0.583,0.577,0.589,0.585,0.601,0.579,0.531,0.504,0.566,0.568,0.582,0.591,0.583,0.558,0.598,0.504,0.603,0.595,0.594,0.589,0.536,0.586,0.592,0.561,0.536,0.529,0.499,0.498,0.39,0.379,0.401,0.412,0.488,0.494,0.493,0.495,0.481,0.589,0.576,4670,Activity,ANCSZ,Medium,Eukaryote
ARGR_ECOLI_Tsuboyama_2023_1AOY,0.277,0.413,0.411,0.43,0.431,0.423,0.306,0.386,0.43,0.463,0.409,0.296,0.405,0.332,0.297,0.511,0.497,0.499,0.435,0.434,0.372,0.439,0.448,0.403,0.362,0.437,0.473,0.461,0.418,0.46,0.409,0.31,0.476,0.073,0.394,0.396,0.43,0.405,0.415,0.439,0.465,0.46,0.471,0.285,0.267,0.45,0.408,0.725,0.651,0.738,0.636,0.513,0.532,0.527,0.529,0.517,0.508,0.503,0.526,0.494,0.533,0.604,0.511,0.488,0.469,0.651,0.656,0.637,0.645,0.619,0.609,0.508,0.598,0.567,0.584,0.55,0.636,0.577,0.352,0.729,0.585,0.534,0.384,0.407,0.397,0.334,0.108,0.137,0.36,0.371,0.421,0.457,0.427,0.367,0.308,0.643,0.526,1287,Stability,ARGR_ECOLI,Medium,Prokaryote
B2L11_HUMAN_Dutta_2010_binding-Mcl-1,0.688,0.27,0.668,0.661,0.53,0.646,0.216,0.529,0.188,0.164,0.206,-0.019,0.396,0.174,0.123,0.151,0.27,0.367,0.315,0.336,0.239,0.076,0.304,0.568,0.067,0.251,0.362,0.372,0.366,0.734,0.358,0.338,0.352,0.295,0.266,0.213,0.341,0.544,0.469,0.388,0.615,0.57,0.402,0.146,0.138,0.207,0.17,0.287,0.307,0.432,-0.005,0.352,0.367,0.419,0.283,0.255,0.47,0.295,0.288,0.421,0.374,0.242,0.204,0.512,0.398,0.377,0.483,0.357,0.336,0.332,0.669,0.444,0.404,0.604,0.544,0.712,0.478,0.677,0.684,0.316,0.165,0.036,0.287,0.609,0.47,0.312,0.239,0.213,0.324,0.44,0.341,0.238,0.296,0.229,0.222,0.417,0.471,170,Binding,B2L11_HUMAN,Low,Human
BBC1_YEAST_Tsuboyama_2023_1TG0,0.216,0.332,0.395,0.399,0.394,0.403,0.212,0.256,0.438,0.454,0.425,0.425,0.451,0.331,0.421,0.423,0.479,0.458,0.499,0.332,0.335,0.346,0.376,0.343,0.144,0.391,0.403,0.382,0.307,0.338,0.345,0.314,0.382,0.273,0.354,0.261,0.299,0.392,0.338,0.365,0.421,0.386,0.405,0.21,0.113,0.314,0.242,0.558,0.451,0.644,0.566,0.434,0.444,0.457,0.472,0.463,0.463,0.46,0.458,0.471,0.461,0.54,0.579,0.433,0.338,0.464,0.589,0.533,0.534,0.547,0.539,0.395,0.515,0.432,0.51,0.475,0.515,0.476,0.262,0.598,0.522,0.509,0.501,0.474,0.48,0.407,0.274,0.372,0.433,0.325,0.216,0.443,0.388,0.349,0.353,0.544,0.46,2069,Stability,BBC1_YEAST,High,Eukaryote
BCHB_CHLTE_Tsuboyama_2023_2KRU,0.364,0.418,0.357,0.364,0.365,0.382,0.1,0.248,0.383,0.501,0.394,0.329,0.406,0.166,0.182,0.301,0.51,0.521,0.421,0.407,0.122,0.362,0.22,0.376,0.207,0.421,0.281,0.402,0.435,0.607,0.549,0.496,0.54,0.07,0.245,0.294,0.431,0.44,0.44,0.483,0.392,0.396,0.436,0.116,0.109,0.205,0.175,0.579,0.537,0.683,0.564,0.549,0.554,0.563,0.579,0.561,0.581,0.529,0.556,0.543,0.562,0.516,0.296,0.427,0.394,0.31,0.601,0.566,0.579,0.687,0.688,0.635,0.697,0.599,0.506,0.47,0.512,0.478,0.493,0.649,0.45,0.55,0.231,0.528,0.418,0.353,0.045,0.033,0.369,0.246,0.378,0.357,0.316,0.347,0.464,0.588,0.504,1572,Stability,BCHB_CHLTE,Medium,Prokaryote
BLAT_ECOLX_Deng_2012,0.322,0.504,0.508,0.521,0.507,0.508,0.075,0.312,0.513,0.55,0.517,0.501,0.518,0.243,0.354,0.461,0.528,0.461,0.352,0.455,0.375,0.378,0.4,0.383,0.391,0.445,0.453,0.406,0.343,0.464,0.519,0.487,0.515,0.107,0.392,0.402,0.373,0.457,0.471,0.473,0.513,0.526,0.522,0.33,0.011,0.48,0.406,0.423,0.496,0.46,0.252,0.53,0.535,0.538,0.552,0.548,0.542,0.544,0.53,0.541,0.555,0.539,0.406,0.536,0.391,0.496,0.542,0.523,0.543,0.498,0.552,0.49,0.491,0.482,0.553,0.565,0.554,0.569,0.436,0.538,0.51,0.527,0.482,0.499,0.44,0.429,0.295,0.05,0.28,0.354,0.366,0.369,0.407,0.4,0.41,0.537,0.56,4996,OrganismalFitness,BLAT_ECOLX,High,Prokaryote
BLAT_ECOLX_Firnberg_2014,0.471,0.708,0.732,0.747,0.709,0.729,0.134,0.459,0.701,0.741,0.703,0.665,0.707,0.411,0.555,0.658,0.737,0.573,0.424,0.662,0.566,0.563,0.537,0.531,0.595,0.646,0.654,0.577,0.452,0.683,0.758,0.752,0.749,0.186,0.551,0.529,0.48,0.646,0.638,0.637,0.731,0.734,0.736,0.54,0.046,0.7,0.595,0.616,0.703,0.696,0.321,0.718,0.699,0.703,0.729,0.739,0.73,0.736,0.72,0.729,0.745,0.754,0.605,0.732,0.583,0.7,0.748,0.76,0.777,0.766,0.777,0.744,0.763,0.713,0.76,0.794,0.756,0.795,0.638,0.761,0.708,0.739,0.642,0.658,0.57,0.642,0.429,0.029,0.254,0.514,0.534,0.521,0.542,0.528,0.49,0.752,0.755,4783,OrganismalFitness,BLAT_ECOLX,High,Prokaryote
BLAT_ECOLX_Jacquier_2013,0.456,0.689,0.698,0.72,0.703,0.723,0.113,0.441,0.665,0.712,0.668,0.656,0.684,0.362,0.52,0.626,0.704,0.588,0.503,0.635,0.564,0.537,0.542,0.528,0.573,0.632,0.625,0.578,0.462,0.567,0.719,0.691,0.692,0.143,0.54,0.549,0.508,0.628,0.642,0.647,0.716,0.728,0.734,0.482,0.04,0.663,0.562,0.527,0.64,0.603,0.29,0.677,0.671,0.672,0.691,0.686,0.686,0.702,0.677,0.684,0.703,0.709,0.573,0.694,0.56,0.645,0.697,0.694,0.715,0.671,0.711,0.604,0.669,0.654,0.707,0.753,0.701,0.754,0.633,0.691,0.677,0.705,0.626,0.677,0.619,0.638,0.416,0.043,0.38,0.519,0.55,0.541,0.564,0.531,0.532,0.712,0.749,989,OrganismalFitness,BLAT_ECOLX,High,Prokaryote
BLAT_ECOLX_Stiffler_2015,0.466,0.707,0.732,0.743,0.711,0.727,0.115,0.459,0.688,0.731,0.698,0.668,0.707,0.399,0.557,0.661,0.731,0.589,0.43,0.655,0.568,0.57,0.528,0.525,0.597,0.651,0.661,0.577,0.46,0.679,0.767,0.761,0.745,0.158,0.558,0.522,0.475,0.645,0.63,0.629,0.73,0.731,0.733,0.532,0.03,0.703,0.598,0.604,0.693,0.682,0.324,0.715,0.692,0.698,0.72,0.725,0.724,0.729,0.709,0.724,0.737,0.748,0.593,0.732,0.581,0.687,0.747,0.746,0.767,0.76,0.769,0.746,0.756,0.715,0.748,0.787,0.744,0.788,0.645,0.753,0.706,0.735,0.651,0.663,0.584,0.646,0.434,0.028,0.27,0.503,0.525,0.511,0.541,0.524,0.499,0.747,0.785,4996,OrganismalFitness,BLAT_ECOLX,High,Prokaryote
BRCA1_HUMAN_Findlay_2018,0.501,0.385,0.441,0.432,0.424,0.466,0.125,0.189,0.387,0.407,0.494,0.404,0.447,0.134,0.392,0.455,0.515,0.497,0.394,0.296,0.145,0.379,0.405,0.361,0.305,0.473,0.457,0.442,0.423,0.438,0.539,0.482,0.523,0.22,0.151,0.179,0.409,0.456,0.456,0.514,0.475,0.476,0.533,0.229,0.132,0.534,0.457,0.44,0.469,0.116,0.12,0.515,0.501,0.506,0.502,0.512,0.504,0.513,0.512,0.504,0.519,0.539,0.481,0.558,0.32,0.395,0.407,0.435,0.467,0.497,0.412,0.507,0.543,0.454,0.524,0.551,0.535,0.56,0.512,0.462,0.51,0.541,0.507,0.5,0.519,0.373,0.388,0.021,0.397,0.145,0.146,0.152,0.329,0.392,0.372,0.491,0.524,1837,OrganismalFitness,BRCA1_HUMAN,Low,Human
BRCA2_HUMAN_Erwood_2022_HEK293T,0.481,0.346,0.44,0.445,0.447,0.481,0.095,0.477,0.095,-0.03,0.48,0.183,0.103,0.088,0.103,0.416,0.51,0.464,0.473,0.033,0.09,0.494,0.534,0.482,0.533,0.483,0.496,0.499,0.014,0.4,0.297,0.328,0.164,0.14,0.119,0.185,0.138,0.42,0.425,0.426,0.419,0.415,0.414,0.163,0.093,0.497,0.047,0.052,0.053,-0.091,0.285,0.436,0.477,0.473,0.424,0.455,0.436,0.456,0.438,0.453,0.465,0.0,0.016,0.464,-0.066,-0.087,-0.027,-0.003,0.003,0.123,0.065,0.4,0.321,0.517,0.533,0.519,0.505,0.502,0.453,0.467,0.437,0.496,0.444,0.459,0.465,0.454,0.431,0.202,0.355,0.023,0.087,0.062,0.273,0.511,0.484,0.527,0.496,265,OrganismalFitness,BRCA2_HUMAN,Low,Human
C6KNH7_9INFA_Lee_2018,0.393,0.371,0.351,0.357,0.433,0.436,-0.025,0.451,0.374,0.378,0.06,0.428,0.492,-0.014,-0.022,-0.007,0.483,0.405,0.426,0.343,0.396,0.363,0.378,0.349,0.254,0.454,0.428,0.465,0.37,0.475,0.457,0.36,0.5,0.11,0.354,0.374,0.392,0.412,0.419,0.433,0.439,0.441,0.452,-0.024,-0.033,0.294,-0.002,0.513,0.539,0.544,0.227,0.498,0.497,0.519,0.52,0.531,0.51,0.528,0.519,0.521,0.529,0.313,0.185,0.238,0.077,0.264,0.296,0.34,0.353,0.445,0.35,0.535,0.505,0.533,0.523,0.573,0.553,0.591,0.512,0.444,-0.01,-0.009,0.027,0.463,0.504,0.438,0.316,0.033,0.339,0.374,0.385,0.39,0.368,0.391,0.39,0.568,0.508,10754,OrganismalFitness,C6KNH7_9INFA,Medium,Virus
CALM1_HUMAN_Weile_2017,0.175,0.233,0.238,0.233,0.238,0.236,0.174,0.187,0.236,0.253,0.25,0.235,0.264,0.161,0.199,0.195,0.212,0.218,0.225,0.229,0.173,0.227,0.242,0.254,0.232,0.276,0.279,0.3,0.313,0.239,0.21,0.146,0.218,0.087,0.216,0.253,0.291,0.218,0.242,0.266,0.238,0.244,0.246,0.213,0.156,0.268,0.251,0.106,0.143,0.164,0.088,0.177,0.182,0.188,0.171,0.189,0.176,0.18,0.192,0.178,0.188,0.287,0.238,0.244,0.189,0.194,0.207,0.225,0.204,0.206,0.238,0.235,0.202,0.184,0.197,0.227,0.194,0.226,0.215,0.2,0.27,0.252,0.262,0.279,0.302,0.166,0.04,0.131,0.24,0.201,0.201,0.218,0.248,0.257,0.276,0.192,0.282,1813,OrganismalFitness,CALM1_HUMAN,High,Human
CAPSD_AAV2S_Sinai_2021,0.407,0.345,0.317,0.372,0.346,0.33,0.374,0.424,0.329,0.363,0.183,0.196,0.199,0.254,0.286,0.203,0.277,0.183,0.124,0.258,0.191,0.25,0.269,0.279,0.203,0.198,0.266,0.204,0.399,0.445,0.183,0.177,0.207,0.132,0.202,0.262,0.492,0.38,0.386,0.473,0.338,0.343,0.426,0.092,0.16,0.26,0.112,0.402,0.393,0.347,0.319,0.235,0.225,0.216,0.235,0.214,0.215,0.22,0.208,0.228,0.223,0.301,0.222,0.572,0.036,0.378,0.571,0.42,0.561,0.34,0.592,0.514,0.392,0.555,0.404,0.437,0.421,0.427,0.494,0.372,0.21,0.174,0.212,0.244,0.207,0.101,0.069,0.241,0.305,0.197,0.276,0.224,0.197,0.22,0.232,0.487,0.577,42328,OrganismalFitness,CAPSD_AAV2S,Low,Virus
CAR11_HUMAN_Meitlis_2020_gof,0.265,0.174,0.164,0.15,0.169,0.184,0.1,0.009,0.218,0.245,0.304,0.324,0.302,0.068,0.095,0.337,0.326,0.345,0.357,0.165,0.151,0.198,0.219,0.216,0.037,0.215,0.229,0.226,0.167,0.179,0.326,0.296,0.38,0.189,0.005,0.148,0.124,0.203,0.208,0.182,0.204,0.201,0.182,0.089,0.043,0.261,0.215,0.318,0.294,0.335,0.142,0.343,0.337,0.335,0.323,0.33,0.331,0.317,0.344,0.346,0.342,0.408,0.333,0.33,0.232,0.258,0.271,0.283,0.299,0.354,0.307,0.289,0.37,0.344,0.356,0.32,0.354,0.32,0.226,0.302,0.281,0.307,0.236,0.23,0.231,0.169,0.181,0.111,0.186,0.097,0.056,0.07,0.078,0.223,0.229,0.337,0.268,2374,OrganismalFitness,CAR11_HUMAN,Low,Human
CAR11_HUMAN_Meitlis_2020_lof,0.421,0.313,0.277,0.258,0.31,0.327,0.108,-0.014,0.299,0.293,0.446,0.49,0.461,0.072,0.115,0.462,0.501,0.533,0.54,0.239,0.141,0.312,0.3,0.277,0.107,0.303,0.306,0.358,0.191,0.338,0.433,0.378,0.554,0.334,-0.003,0.264,0.195,0.29,0.325,0.271,0.32,0.326,0.281,0.087,0.041,0.417,0.311,0.417,0.445,0.451,0.175,0.518,0.521,0.515,0.508,0.5,0.518,0.503,0.512,0.526,0.525,0.579,0.425,0.488,0.31,0.34,0.382,0.397,0.414,0.468,0.434,0.426,0.495,0.471,0.535,0.495,0.528,0.488,0.366,0.427,0.438,0.474,0.38,0.379,0.371,0.341,0.298,0.12,0.302,0.048,0.032,0.119,0.126,0.383,0.357,0.459,0.42,2395,OrganismalFitness,CAR11_HUMAN,Low,Human
CAS9_STRP1_Spencer_2017_positive,0.159,0.179,0.162,0.166,0.169,0.177,0.04,0.1,0.18,0.183,0.175,0.069,0.073,0.063,0.09,0.154,0.182,0.188,0.194,0.006,0.043,0.081,0.173,0.12,0.043,0.194,0.182,0.179,0.068,0.187,0.199,0.179,0.187,0.027,0.035,0.047,0.166,0.17,0.172,0.189,0.184,0.184,0.194,0.061,0.028,0.181,0.106,0.106,0.181,0.036,0.037,0.176,0.177,0.178,0.185,0.18,0.181,0.177,0.178,0.177,0.183,0.177,0.114,0.201,0.078,0.122,0.134,0.136,0.142,0.17,0.143,0.196,0.182,0.18,0.187,0.195,0.191,0.198,0.189,0.141,0.165,0.175,0.151,0.202,0.204,0.142,0.081,0.01,0.167,0.116,0.167,0.185,0.204,0.191,0.17,0.188,0.201,8117,Activity,CAS9_STRP1,Medium,Prokaryote
CASP3_HUMAN_Roychowdhury_2020,0.382,0.543,0.61,0.622,0.626,0.632,0.054,0.478,0.644,0.653,0.59,0.595,0.624,0.264,0.574,0.639,0.638,0.554,0.514,0.603,0.233,0.512,0.517,0.532,0.505,0.556,0.554,0.526,0.567,0.608,0.599,0.542,0.627,0.217,0.092,0.482,0.52,0.533,0.562,0.582,0.628,0.619,0.628,0.422,-0.006,0.616,0.563,0.414,0.558,0.499,0.263,0.553,0.571,0.571,0.57,0.575,0.567,0.585,0.571,0.576,0.59,0.652,0.513,0.626,0.316,0.31,0.34,0.388,0.389,0.55,0.395,0.625,0.555,0.584,0.623,0.647,0.624,0.646,0.55,0.573,0.659,0.661,0.618,0.626,0.641,0.519,0.338,0.196,0.623,0.209,0.312,0.453,0.532,0.541,0.562,0.632,0.674,1567,Activity,CASP3_HUMAN,High,Human
CASP7_HUMAN_Roychowdhury_2020,0.372,0.516,0.619,0.617,0.609,0.613,0.057,0.47,0.6,0.627,0.585,0.611,0.632,0.306,0.598,0.632,0.622,0.572,0.562,0.611,0.206,0.532,0.529,0.558,0.529,0.579,0.589,0.563,0.572,0.642,0.596,0.538,0.607,0.332,0.103,0.543,0.521,0.517,0.594,0.586,0.599,0.628,0.628,0.461,0.019,0.646,0.596,0.479,0.612,0.573,0.329,0.585,0.57,0.562,0.587,0.608,0.602,0.591,0.578,0.596,0.605,0.643,0.533,0.644,0.344,0.348,0.388,0.388,0.411,0.518,0.432,0.631,0.538,0.629,0.6,0.645,0.622,0.655,0.567,0.626,0.648,0.659,0.642,0.611,0.606,0.532,0.394,0.19,0.592,0.206,0.343,0.506,0.561,0.546,0.557,0.64,0.653,1680,Activity,CASP7_HUMAN,Medium,Human
CATR_CHLRE_Tsuboyama_2023_2AMI,0.533,0.559,0.599,0.606,0.627,0.63,0.68,0.558,0.565,0.528,0.614,0.638,0.657,0.564,0.689,0.688,0.658,0.615,0.644,0.041,0.621,0.603,0.619,0.602,0.641,0.627,0.593,0.561,0.587,0.649,0.611,0.619,0.681,0.439,0.626,0.611,0.633,0.649,0.642,0.665,0.622,0.62,0.638,0.44,0.427,0.315,0.46,0.475,0.4,0.679,0.572,0.663,0.652,0.676,0.668,0.687,0.662,0.67,0.653,0.663,0.674,0.62,0.686,0.643,0.601,0.728,0.737,0.75,0.741,0.735,0.77,0.651,0.736,0.679,0.668,0.671,0.675,0.678,0.612,0.676,0.637,0.623,0.616,0.604,0.617,0.543,0.297,0.481,0.535,0.663,0.633,0.636,0.604,0.608,0.568,0.725,0.668,1903,Stability,CATR_CHLRE,High,Eukaryote
CBPA2_HUMAN_Tsuboyama_2023_1O6X,0.644,0.718,0.744,0.745,0.716,0.729,0.482,0.577,0.745,0.754,0.77,0.752,0.736,0.529,0.688,0.736,0.702,0.727,0.718,0.739,0.486,0.522,0.699,0.692,0.547,0.665,0.673,0.674,0.71,0.732,0.71,0.654,0.746,0.104,0.509,0.642,0.703,0.699,0.706,0.732,0.746,0.736,0.748,0.51,0.302,0.631,0.646,0.701,0.689,0.82,0.773,0.772,0.768,0.778,0.768,0.782,0.78,0.77,0.772,0.769,0.779,0.716,0.835,0.746,0.734,0.805,0.848,0.852,0.852,0.869,0.86,0.746,0.861,0.76,0.731,0.758,0.73,0.762,0.699,0.825,0.767,0.73,0.719,0.728,0.758,0.608,0.418,-0.048,0.729,0.37,0.592,0.61,0.66,0.662,0.639,0.777,0.755,2068,Stability,CBPA2_HUMAN,Medium,Human
CBS_HUMAN_Sun_2020,0.334,0.358,0.364,0.383,0.371,0.379,0.202,0.251,0.374,0.377,0.347,0.346,0.372,0.085,0.226,0.335,0.342,0.329,0.339,0.35,0.356,0.26,0.285,0.288,0.349,0.273,0.29,0.273,0.31,0.381,0.37,0.344,0.311,0.197,0.361,0.283,0.266,0.384,0.332,0.327,0.394,0.363,0.363,0.304,0.068,0.376,0.373,0.237,0.268,0.309,0.079,0.324,0.324,0.331,0.337,0.337,0.335,0.332,0.332,0.335,0.34,0.386,0.289,0.377,0.176,0.141,0.164,0.192,0.167,0.295,0.167,0.375,0.328,0.379,0.333,0.376,0.335,0.378,0.39,0.343,0.394,0.394,0.372,0.374,0.359,0.257,0.267,0.159,0.358,0.353,0.356,0.362,0.324,0.273,0.293,0.372,0.398,7217,OrganismalFitness,CBS_HUMAN,Medium,Human
CBX4_HUMAN_Tsuboyama_2023_2K28,0.498,0.548,0.674,0.706,0.633,0.685,-0.266,0.611,0.623,0.613,0.615,0.65,0.648,-0.271,0.735,0.699,0.682,0.609,0.606,0.648,0.486,0.589,0.581,0.587,0.553,0.577,0.589,0.531,0.569,0.633,0.667,0.653,0.654,0.423,0.425,0.505,0.54,0.601,0.6,0.623,0.676,0.698,0.701,0.621,-0.32,0.369,0.561,0.167,0.155,0.614,0.588,0.695,0.626,0.69,0.676,0.709,0.668,0.677,0.718,0.664,0.695,0.642,0.751,0.695,-0.065,0.284,0.648,0.677,0.675,0.608,0.607,0.616,0.623,0.656,0.689,0.699,0.689,0.695,0.639,0.663,0.627,0.611,0.666,0.657,0.619,0.459,0.433,0.369,0.574,-0.289,0.375,0.505,0.574,0.599,0.603,0.697,0.679,2282,Stability,CBX4_HUMAN,High,Human
CCDB_ECOLI_Adkar_2012,0.357,0.486,0.52,0.547,0.528,0.531,-0.031,0.185,0.341,0.361,0.424,0.351,0.432,-0.006,-0.018,0.406,0.466,0.463,0.264,0.457,0.027,-0.015,-0.115,0.142,-0.139,0.053,-0.029,0.034,0.425,0.453,0.554,0.555,0.5,0.124,0.006,0.056,0.31,0.442,0.426,0.458,0.507,0.494,0.522,0.018,-0.05,0.444,0.02,0.285,0.426,0.343,0.242,0.436,0.401,0.414,0.443,0.437,0.454,0.436,0.464,0.486,0.453,0.438,0.194,0.486,-0.054,0.603,0.636,0.707,0.67,0.415,0.661,0.573,0.406,0.519,0.446,0.532,0.436,0.53,0.383,0.401,0.476,0.472,0.408,0.453,0.518,-0.008,-0.094,0.012,0.322,-0.05,0.068,0.111,0.224,0.424,0.487,0.494,0.373,1176,Activity,CCDB_ECOLI,High,Prokaryote
CCDB_ECOLI_Tripathi_2016,0.434,0.506,0.524,0.541,0.517,0.528,-0.008,0.294,0.403,0.431,0.49,0.435,0.483,-0.007,-0.001,0.462,0.511,0.522,0.362,0.518,0.034,0.014,-0.074,0.171,-0.107,0.094,-0.029,0.074,0.476,0.505,0.542,0.51,0.559,0.112,0.009,0.129,0.424,0.48,0.48,0.532,0.518,0.517,0.548,0.005,-0.055,0.495,0.017,0.317,0.433,0.335,0.23,0.486,0.449,0.449,0.482,0.483,0.48,0.473,0.49,0.517,0.492,0.49,0.326,0.553,0.087,0.509,0.547,0.566,0.565,0.485,0.569,0.558,0.484,0.436,0.478,0.547,0.466,0.543,0.457,0.448,0.542,0.535,0.486,0.5,0.545,-0.054,-0.075,0.002,0.43,-0.019,0.094,0.17,0.315,0.438,0.533,0.503,0.534,1663,OrganismalFitness,CCDB_ECOLI,High,Prokaryote
CCR5_HUMAN_Gill_2023,0.271,0.279,0.282,0.289,0.274,0.282,0.316,0.309,0.333,0.343,0.358,0.344,0.356,0.325,0.358,0.362,0.347,0.339,0.341,0.352,0.367,0.366,0.323,0.326,0.369,0.356,0.346,0.36,0.322,0.364,0.3,0.251,0.355,0.13,0.367,0.365,0.363,0.367,0.375,0.376,0.324,0.324,0.323,0.354,0.175,0.362,0.361,0.278,0.306,0.291,0.173,0.314,0.305,0.316,0.318,0.313,0.317,0.328,0.323,0.327,0.327,0.348,0.356,0.346,0.28,0.297,0.284,0.302,0.284,0.363,0.313,0.364,0.364,0.323,0.333,0.33,0.321,0.318,0.332,0.302,0.349,0.353,0.343,0.318,0.323,0.33,0.29,0.268,0.315,0.348,0.352,0.349,0.368,0.355,0.338,0.331,0.35,6137,Binding,CCR5_HUMAN,High,Human
CD19_HUMAN_Klesmith_2019_FMC_singles,0.189,0.247,0.199,0.211,0.234,0.232,0.051,0.233,0.257,0.261,0.046,0.05,0.072,0.09,0.093,0.054,0.05,0.123,0.217,-0.013,0.096,0.124,0.118,0.119,0.042,0.12,0.112,0.093,0.244,0.283,0.194,0.159,0.179,0.077,0.075,0.12,0.093,0.203,0.21,0.202,0.233,0.235,0.231,0.083,0.05,0.104,0.086,0.316,0.258,0.301,0.174,0.158,0.18,0.173,0.196,0.186,0.195,0.204,0.17,0.185,0.195,0.312,0.244,0.276,0.209,0.263,0.243,0.215,0.267,0.287,0.265,0.248,0.291,0.264,0.203,0.255,0.219,0.264,0.259,0.291,0.065,0.055,0.047,0.045,0.059,0.111,0.132,-0.039,0.245,0.039,0.041,0.103,0.117,0.091,0.158,0.25,0.273,3761,Binding,CD19_HUMAN,Low,Human
CP2C9_HUMAN_Amorosi_2021_abundance,0.505,0.572,0.594,0.611,0.596,0.61,0.529,0.555,0.601,0.615,0.513,0.588,0.621,0.531,0.605,0.625,0.635,0.626,0.591,0.611,0.553,0.548,0.587,0.558,0.571,0.585,0.59,0.572,0.572,0.605,0.573,0.511,0.605,0.208,0.581,0.563,0.569,0.618,0.618,0.624,0.634,0.63,0.632,0.579,0.116,0.534,0.607,0.555,0.538,0.607,0.218,0.6,0.598,0.606,0.629,0.631,0.623,0.622,0.611,0.617,0.635,0.637,0.618,0.611,0.576,0.496,0.538,0.534,0.546,0.632,0.57,0.625,0.634,0.609,0.647,0.663,0.657,0.671,0.544,0.656,0.608,0.593,0.579,0.559,0.52,0.521,0.457,0.203,0.491,0.533,0.571,0.59,0.596,0.584,0.583,0.641,0.601,6370,Expression,CP2C9_HUMAN,High,Human
CP2C9_HUMAN_Amorosi_2021_activity,0.526,0.59,0.626,0.645,0.616,0.635,0.583,0.615,0.606,0.635,0.519,0.642,0.666,0.57,0.655,0.679,0.679,0.678,0.62,0.652,0.587,0.592,0.619,0.573,0.618,0.587,0.593,0.592,0.582,0.637,0.603,0.544,0.667,0.225,0.638,0.605,0.572,0.666,0.658,0.638,0.668,0.659,0.65,0.638,0.094,0.557,0.666,0.603,0.577,0.656,0.263,0.645,0.649,0.652,0.663,0.674,0.672,0.668,0.656,0.662,0.681,0.673,0.667,0.637,0.626,0.515,0.545,0.536,0.534,0.652,0.591,0.647,0.661,0.66,0.685,0.697,0.697,0.705,0.612,0.697,0.634,0.622,0.613,0.594,0.531,0.582,0.488,0.253,0.512,0.558,0.606,0.651,0.66,0.635,0.591,0.709,0.632,6142,Binding,CP2C9_HUMAN,High,Human
CSN4_MOUSE_Tsuboyama_2023_1UFM,0.389,0.504,0.432,0.445,0.47,0.477,0.26,0.4,0.461,0.461,0.481,0.546,0.605,0.449,0.686,0.518,0.484,0.423,0.415,0.406,0.449,0.455,0.502,0.514,0.443,0.587,0.53,0.504,0.501,0.532,0.401,0.389,0.54,0.244,0.341,0.474,0.546,0.497,0.536,0.576,0.468,0.513,0.53,0.416,0.326,0.494,0.538,0.562,0.541,0.653,0.62,0.531,0.52,0.532,0.557,0.58,0.556,0.539,0.58,0.548,0.556,0.575,0.72,0.513,0.574,0.731,0.701,0.704,0.684,0.752,0.641,0.585,0.762,0.554,0.55,0.585,0.534,0.591,0.463,0.711,0.514,0.537,0.549,0.405,0.463,0.544,0.4,-0.095,0.402,0.448,0.486,0.584,0.609,0.585,0.568,0.675,0.552,3295,Stability,CSN4_MOUSE,Medium,Eukaryote
CUE1_YEAST_Tsuboyama_2023_2MYX,0.357,0.451,0.435,0.438,0.474,0.445,0.154,0.453,0.516,0.547,0.483,0.427,0.398,0.153,0.428,0.478,0.547,0.498,0.467,0.304,0.174,0.206,0.225,0.102,0.117,0.224,0.255,0.248,0.434,0.42,0.469,0.414,0.476,0.231,0.16,0.146,0.213,0.38,0.387,0.393,0.438,0.441,0.448,0.154,0.064,0.462,0.256,0.515,0.501,0.654,0.482,0.549,0.508,0.494,0.552,0.517,0.551,0.538,0.525,0.517,0.538,0.6,0.571,0.557,0.297,0.426,0.598,0.502,0.584,0.64,0.602,0.476,0.648,0.527,0.591,0.56,0.63,0.585,0.403,0.633,0.508,0.539,0.388,0.48,0.526,-0.071,0.065,-0.155,0.482,0.142,0.163,0.117,0.149,0.195,0.199,0.619,0.578,1580,Stability,CUE1_YEAST,Medium,Eukaryote
D7PM05_CLYGR_Somermeyer_2022,0.53,0.625,0.613,0.582,0.629,0.631,0.073,0.475,0.649,0.657,0.439,0.066,0.064,0.068,0.053,0.036,0.05,0.072,0.152,0.438,0.039,0.042,0.114,0.082,0.009,0.047,0.068,0.194,0.361,0.623,0.563,0.574,0.597,0.016,0.096,0.125,0.156,0.536,0.536,0.532,0.63,0.629,0.618,0.004,0.024,0.009,0.028,0.292,0.316,0.505,0.396,0.495,0.491,0.496,0.505,0.494,0.502,0.494,0.49,0.487,0.498,0.345,0.208,0.687,0.187,0.59,0.573,0.601,0.602,0.524,0.631,0.672,0.579,0.686,0.331,0.554,0.393,0.584,0.655,0.477,0.07,0.054,0.042,0.055,0.061,0.076,-0.001,-0.027,0.483,0.034,0.079,0.071,0.079,0.039,0.142,0.664,0.674,24515,Activity,D7PM05_CLYGR,Low,Eukaryote
DLG4_HUMAN_Faure_2021,0.679,0.584,0.607,0.577,0.609,0.616,0.723,0.629,0.524,0.535,0.52,0.55,0.608,0.743,0.764,0.728,0.584,0.487,0.443,0.65,0.574,0.583,0.569,0.538,0.605,0.607,0.564,0.562,0.495,0.614,0.634,0.621,0.683,0.511,0.576,0.638,0.58,0.653,0.7,0.667,0.643,0.661,0.636,0.581,0.233,0.372,0.528,0.637,0.453,0.672,0.315,0.483,0.37,0.539,0.499,0.52,0.492,0.508,0.486,0.504,0.504,0.521,0.745,0.735,0.689,0.674,0.663,0.673,0.685,0.739,0.705,0.635,0.722,0.649,0.554,0.607,0.585,0.625,0.614,0.681,0.557,0.562,0.54,0.517,0.51,0.524,0.551,0.456,0.324,0.67,0.611,0.605,0.676,0.633,0.57,0.742,0.699,6976,OrganismalFitness,DLG4_HUMAN,Low,Human
DLG4_RAT_McLaughlin_2012,0.486,0.442,0.487,0.491,0.526,0.539,0.49,0.437,0.483,0.522,0.469,0.557,0.588,0.411,0.543,0.581,0.543,0.478,0.471,0.444,0.378,0.389,0.373,0.371,0.407,0.42,0.407,0.367,0.395,0.49,0.556,0.537,0.538,0.246,0.367,0.392,0.307,0.47,0.478,0.443,0.538,0.544,0.54,0.527,0.076,0.443,0.5,0.439,0.308,0.459,0.135,0.442,0.375,0.444,0.433,0.444,0.43,0.43,0.464,0.46,0.469,0.504,0.535,0.583,0.504,0.505,0.532,0.523,0.546,0.525,0.544,0.517,0.544,0.541,0.505,0.579,0.549,0.599,0.475,0.559,0.575,0.543,0.508,0.499,0.448,0.34,0.388,0.23,0.224,0.383,0.38,0.325,0.271,0.355,0.315,0.536,0.593,1576,Binding,DLG4_RAT,Low,Eukaryote
DN7A_SACS2_Tsuboyama_2023_1JIC,0.171,0.198,0.218,0.23,0.2,0.259,-0.071,0.317,0.368,0.386,0.085,0.126,0.131,0.074,0.209,0.255,0.337,0.337,0.37,0.235,-0.068,0.045,0.033,0.066,0.041,0.107,0.057,0.071,0.235,0.298,0.431,0.351,0.47,0.054,-0.013,-0.023,0.031,0.212,0.2,0.211,0.243,0.227,0.231,0.106,-0.048,0.299,0.129,0.568,0.56,0.66,0.556,0.424,0.436,0.516,0.507,0.491,0.476,0.472,0.444,0.436,0.49,0.556,0.481,0.349,0.355,0.594,0.62,0.7,0.636,0.696,0.701,0.44,0.674,0.5,0.558,0.466,0.574,0.48,0.238,0.664,0.276,0.304,0.227,0.225,0.21,0.029,-0.041,0.116,0.135,0.023,0.114,0.08,0.143,0.16,0.202,0.483,0.448,1008,Stability,DN7A_SACS2,Medium,Prokaryote
DNJA1_HUMAN_Tsuboyama_2023_2LO1,0.738,0.75,0.759,0.757,0.767,0.764,0.756,0.732,0.776,0.79,0.773,0.756,0.785,0.827,0.816,0.817,0.803,0.753,0.798,0.781,0.669,0.736,0.776,0.75,0.782,0.765,0.774,0.721,0.764,0.775,0.729,0.714,0.803,0.66,0.78,0.776,0.805,0.808,0.816,0.823,0.774,0.787,0.787,0.67,0.164,0.443,0.684,0.643,0.528,0.779,0.785,0.757,0.761,0.76,0.793,0.789,0.803,0.789,0.786,0.794,0.786,0.726,0.801,0.799,0.723,0.859,0.864,0.865,0.849,0.844,0.876,0.779,0.837,0.804,0.762,0.795,0.809,0.808,0.769,0.84,0.777,0.758,0.783,0.754,0.736,0.614,0.362,0.547,0.663,0.725,0.742,0.762,0.754,0.731,0.724,0.843,0.782,2264,Stability,DNJA1_HUMAN,High,Human
DOCK1_MOUSE_Tsuboyama_2023_2M0Y,0.418,0.453,0.421,0.439,0.494,0.501,0.057,0.432,0.406,0.403,0.525,0.472,0.501,0.224,0.458,0.486,0.531,0.508,0.531,0.518,0.34,0.418,0.402,0.408,0.315,0.402,0.365,0.348,0.395,0.448,0.471,0.469,0.492,0.216,0.202,0.321,0.252,0.473,0.49,0.494,0.489,0.491,0.507,0.359,-0.177,0.513,0.439,0.38,0.394,0.419,0.439,0.492,0.481,0.497,0.507,0.491,0.512,0.477,0.493,0.504,0.497,0.567,0.531,0.525,0.159,0.407,0.448,0.557,0.559,0.594,0.573,0.55,0.602,0.543,0.511,0.53,0.525,0.537,0.495,0.517,0.477,0.472,0.416,0.377,0.446,0.209,0.327,0.146,0.372,0.21,0.187,0.163,0.259,0.26,0.199,0.518,0.524,2915,Stability,DOCK1_MOUSE,High,Eukaryote
DYR_ECOLI_Nguyen_2023,0.34,0.424,0.448,0.453,0.451,0.454,0.004,0.425,0.505,0.481,0.523,0.535,0.545,0.133,0.5,0.525,0.544,0.529,0.511,0.502,0.373,0.421,0.281,0.342,0.435,0.388,0.387,0.454,0.333,0.48,0.502,0.477,0.507,0.148,0.405,0.235,0.225,0.46,0.33,0.356,0.459,0.406,0.418,0.469,0.013,0.519,0.499,0.264,0.428,0.374,0.157,0.501,0.459,0.47,0.483,0.492,0.49,0.503,0.495,0.511,0.505,0.511,0.471,0.517,0.221,0.302,0.374,0.306,0.347,0.465,0.422,0.468,0.485,0.492,0.515,0.508,0.508,0.504,0.442,0.438,0.532,0.518,0.532,0.489,0.496,0.446,0.329,-0.016,0.365,0.477,0.435,0.339,0.233,0.26,0.292,0.487,0.477,2916,OrganismalFitness,DYR_ECOLI,High,Prokaryote
DYR_ECOLI_Thompson_2019,0.384,0.484,0.469,0.472,0.476,0.474,-0.018,0.321,0.47,0.501,0.469,0.416,0.436,0.055,0.349,0.455,0.48,0.506,0.512,0.485,0.199,0.36,0.266,0.31,0.342,0.436,0.476,0.441,0.418,0.451,0.451,0.408,0.488,0.1,0.355,0.348,0.347,0.407,0.415,0.423,0.459,0.476,0.481,0.318,-0.019,0.442,0.39,0.248,0.403,0.321,0.111,0.44,0.411,0.415,0.418,0.435,0.422,0.441,0.442,0.455,0.445,0.491,0.387,0.488,0.148,0.306,0.422,0.383,0.479,0.48,0.472,0.481,0.477,0.433,0.446,0.488,0.459,0.495,0.416,0.413,0.501,0.508,0.476,0.49,0.47,0.407,0.232,-0.051,0.378,0.368,0.424,0.455,0.414,0.381,0.393,0.477,0.476,2363,OrganismalFitness,DYR_ECOLI,Medium,Prokaryote
ENV_HV1B9_DuenasDecamp_2016,0.369,0.397,0.238,0.367,0.388,0.377,0.056,0.353,0.341,0.366,0.359,0.415,0.389,0.11,0.055,0.035,0.012,0.048,0.095,0.388,0.38,0.358,0.408,0.419,0.263,0.394,0.401,0.391,0.374,0.389,0.355,0.322,0.236,0.253,0.368,0.373,0.404,0.392,0.396,0.407,0.39,0.392,0.392,0.343,-0.04,0.334,0.395,0.355,0.325,0.364,0.231,0.215,0.261,0.274,0.24,0.214,0.233,0.241,0.258,0.24,0.263,0.15,0.102,0.362,-0.01,0.507,0.404,0.481,0.553,0.258,0.611,0.397,0.294,0.276,0.351,0.416,0.264,0.381,0.375,0.357,0.39,0.398,0.282,0.374,0.379,0.332,0.294,0.122,0.387,0.229,0.305,0.25,0.322,0.384,0.351,0.376,0.336,375,OrganismalFitness,ENV_HV1B9,Medium,Virus
ENV_HV1BR_Haddox_2016,0.338,0.303,0.322,0.323,0.339,0.345,-0.001,0.322,0.345,0.344,0.298,0.32,0.336,-0.009,-0.006,0.004,0.046,0.069,0.16,0.337,0.35,0.358,0.371,0.364,0.345,0.358,0.358,0.354,0.362,0.35,0.325,0.29,0.271,0.189,0.344,0.36,0.358,0.359,0.366,0.362,0.367,0.369,0.365,0.233,-0.013,0.321,0.293,0.212,0.245,0.119,0.072,0.18,0.179,0.203,0.226,0.188,0.202,0.2,0.192,0.193,0.209,0.167,0.098,0.335,0.039,0.217,0.248,0.238,0.243,0.292,0.269,0.358,0.323,0.281,0.214,0.357,0.233,0.366,0.334,0.219,0.323,0.318,0.324,0.343,0.337,0.326,0.229,0.021,0.248,0.303,0.325,0.324,0.339,0.344,0.337,0.36,0.344,12863,OrganismalFitness,ENV_HV1BR,Medium,Virus
ENVZ_ECOLI_Ghose_2023,0.115,0.095,0.18,0.178,0.187,0.188,0.04,0.19,0.19,0.198,0.154,0.204,0.209,0.194,0.207,0.195,0.172,0.154,0.113,0.183,0.164,0.152,0.201,0.183,0.176,0.164,0.199,0.183,0.163,0.178,0.133,0.135,0.175,0.142,0.18,0.184,0.193,0.207,0.213,0.215,0.195,0.201,0.199,0.194,0.134,0.187,0.185,0.055,0.149,0.114,0.036,0.189,0.186,0.168,0.188,0.22,0.197,0.183,0.19,0.2,0.199,0.148,0.224,0.163,0.131,0.207,0.254,0.212,0.236,0.25,0.232,0.132,0.246,0.171,0.167,0.185,0.17,0.188,0.148,0.197,0.178,0.161,0.198,0.087,0.122,0.12,-0.079,-0.023,0.021,0.133,0.173,0.153,0.18,0.166,0.187,0.234,0.132,1121,Activity,ENVZ_ECOLI,High,Prokaryote
EPHB2_HUMAN_Tsuboyama_2023_1F0M,0.615,0.706,0.705,0.708,0.732,0.733,-0.32,0.684,0.781,0.789,0.762,0.787,0.789,-0.378,0.768,0.803,0.81,0.769,0.744,0.741,0.555,0.599,0.685,0.656,0.641,0.664,0.684,0.705,0.735,0.795,0.752,0.738,0.812,0.677,0.612,0.603,0.644,0.716,0.711,0.728,0.741,0.737,0.735,0.625,-0.253,0.618,0.63,0.665,0.604,0.828,0.76,0.805,0.801,0.806,0.811,0.82,0.809,0.802,0.806,0.8,0.812,0.799,0.805,0.793,0.672,0.786,0.836,0.798,0.825,0.851,0.836,0.823,0.839,0.777,0.821,0.804,0.84,0.813,0.781,0.851,0.815,0.787,0.758,0.747,0.742,0.622,0.625,0.347,0.727,-0.054,0.478,0.5,0.591,0.614,0.663,0.866,0.782,1960,Stability,EPHB2_HUMAN,High,Human
ERBB2_HUMAN_Elazar_2016,0.386,0.368,0.254,0.25,0.244,0.268,0.449,0.415,0.405,0.416,0.449,0.48,0.49,0.481,0.463,0.469,0.423,0.373,0.295,0.047,0.457,0.499,0.55,0.471,0.505,0.536,0.596,0.598,0.506,0.381,0.424,0.066,0.465,0.489,0.553,0.471,0.521,0.494,0.465,0.492,0.447,0.441,0.439,0.468,0.459,0.537,0.463,0.461,0.491,-0.139,0.022,0.41,0.406,0.451,0.44,0.415,0.406,0.432,0.452,0.438,0.446,0.525,0.488,0.5,0.633,0.683,0.603,0.609,0.695,0.597,0.604,0.425,0.552,0.278,0.363,0.343,0.389,0.346,0.29,0.493,0.462,0.481,0.411,0.4,0.37,0.585,0.39,0.278,0.489,0.501,0.55,0.452,0.564,0.516,0.557,0.545,0.511,326,Expression,ERBB2_HUMAN,Low,Human
ESTA_BACSU_Nutschel_2020,0.258,0.399,0.389,0.415,0.387,0.387,0.187,0.315,0.345,0.413,0.336,0.305,0.335,0.169,0.27,0.267,0.3,0.281,0.323,0.32,0.121,0.196,0.268,0.286,0.27,0.254,0.311,0.272,0.379,0.379,0.434,0.406,0.376,0.075,0.184,0.272,0.261,0.31,0.329,0.326,0.403,0.407,0.397,0.193,0.121,0.289,0.262,0.557,0.489,0.545,0.368,0.366,0.334,0.347,0.343,0.378,0.347,0.347,0.365,0.369,0.37,0.391,0.212,0.391,0.147,0.318,0.379,0.418,0.45,0.335,0.443,0.436,0.342,0.499,0.385,0.434,0.431,0.457,0.262,0.475,0.339,0.315,0.264,0.314,0.32,0.312,0.253,0.184,0.362,0.253,0.294,0.319,0.291,0.343,0.302,0.514,0.432,2172,Stability,ESTA_BACSU,High,Prokaryote
F7YBW8_MESOW_Ding_2023,0.572,0.535,0.535,0.55,0.55,0.545,0.499,0.463,0.462,0.468,0.488,0.403,0.436,0.486,0.626,0.632,0.446,0.456,0.479,0.498,0.459,0.525,0.413,0.403,0.531,0.387,0.454,0.38,0.386,0.533,0.556,0.567,0.604,0.269,0.484,0.546,0.577,0.566,0.601,0.598,0.56,0.583,0.564,0.364,0.239,0.309,0.337,0.367,0.452,0.572,0.441,0.493,0.528,0.524,0.552,0.6,0.529,0.51,0.546,0.556,0.539,0.641,0.497,0.498,0.44,0.691,0.711,0.719,0.682,0.692,0.712,0.571,0.685,0.456,0.436,0.494,0.482,0.52,0.551,0.643,0.494,0.534,0.529,0.417,0.437,0.356,0.005,0.002,0.522,0.513,0.495,0.417,0.328,0.367,0.356,0.462,0.532,7922,OrganismalFitness,F7YBW8_MESOW,High,Prokaryote
F7YBW8_MESOW_Aakre_2015,0.06,0.395,0.395,0.44,0.428,0.43,0.016,0.32,0.382,0.395,0.437,0.382,0.393,-0.091,-0.001,0.049,0.383,0.366,0.434,0.391,-0.075,-0.122,-0.104,-0.005,0.098,0.125,-0.021,0.298,0.403,0.375,0.461,0.441,0.431,0.037,-0.036,-0.124,0.433,0.062,0.011,0.425,0.38,0.367,0.444,-0.064,-0.081,0.199,-0.048,-0.008,0.246,0.069,0.035,0.431,0.447,0.423,0.46,0.453,0.457,0.43,0.443,0.447,0.448,0.27,-0.126,0.423,-0.094,0.434,0.394,0.427,0.382,0.104,0.429,0.399,0.095,0.277,0.171,0.349,0.169,0.348,0.409,0.292,0.414,0.445,0.395,0.446,0.476,0.005,0.062,-0.181,0.436,-0.082,0.049,0.038,0.235,0.225,0.384,0.396,0.444,9192,OrganismalFitness,F7YBW8_MESOW,High,Prokaryote
FECA_ECOLI_Tsuboyama_2023_2D1U,0.38,0.431,0.449,0.458,0.449,0.441,0.023,0.297,0.372,0.456,0.509,0.269,0.433,0.059,0.449,0.536,0.524,0.48,0.386,0.464,0.169,0.272,0.343,0.288,0.156,0.477,0.451,0.292,0.394,0.52,0.409,0.336,0.489,0.276,0.065,0.121,0.148,0.355,0.348,0.302,0.415,0.415,0.389,0.395,0.008,0.501,0.447,0.582,0.551,0.588,0.525,0.527,0.483,0.514,0.512,0.5,0.528,0.499,0.489,0.506,0.515,0.595,0.585,0.502,0.301,0.294,0.522,0.547,0.595,0.597,0.574,0.554,0.615,0.497,0.546,0.506,0.546,0.505,0.399,0.614,0.553,0.55,0.497,0.51,0.548,0.263,0.203,0.035,0.364,0.064,0.145,0.342,0.372,0.291,0.376,0.638,0.507,1886,Stability,FECA_ECOLI,High,Prokaryote
FKBP3_HUMAN_Tsuboyama_2023_2KFV,0.423,0.394,0.479,0.482,0.487,0.498,0.18,0.342,0.237,0.237,0.171,0.17,0.164,0.172,0.163,0.147,0.188,0.265,0.378,0.287,0.221,0.213,0.218,0.279,0.169,0.229,0.193,0.25,0.22,0.478,0.315,0.319,0.386,-0.077,0.095,0.168,0.23,0.398,0.41,0.342,0.484,0.49,0.409,0.18,0.184,0.177,0.21,0.685,0.603,0.687,0.589,0.306,0.397,0.443,0.402,0.397,0.403,0.369,0.368,0.296,0.399,0.581,0.368,0.291,0.22,0.546,0.532,0.568,0.575,0.597,0.531,0.546,0.574,0.593,0.522,0.595,0.575,0.623,0.418,0.71,0.153,0.159,0.109,0.169,0.177,0.096,0.006,0.014,0.173,0.121,0.177,0.185,0.184,0.126,0.275,0.647,0.338,1237,Stability,FKBP3_HUMAN,Medium,Human
GAL4_YEAST_Kitzman_2015,0.237,0.403,0.507,0.567,0.486,0.532,0.337,-0.004,0.513,0.575,0.623,0.458,0.462,0.34,0.392,0.528,0.668,0.67,0.655,0.507,0.319,0.355,0.383,0.372,0.364,0.424,0.493,0.451,0.579,0.628,0.651,0.563,0.6,0.303,0.279,0.331,0.325,0.56,0.555,0.557,0.508,0.509,0.503,0.395,0.301,0.604,0.446,0.287,0.568,0.308,0.114,0.627,0.634,0.613,0.625,0.632,0.634,0.62,0.617,0.619,0.638,0.558,0.408,0.64,0.302,0.534,0.531,0.515,0.576,0.586,0.567,0.625,0.576,0.278,0.663,0.644,0.657,0.635,0.36,0.5,0.435,0.552,0.392,0.529,0.585,0.4,-0.048,-0.019,0.65,0.257,0.328,0.33,0.365,0.482,0.536,0.636,0.629,1195,OrganismalFitness,GAL4_YEAST,Medium,Eukaryote
GCN4_YEAST_Staller_2018,0.253,0.25,0.245,0.248,0.242,0.241,0.182,0.221,0.24,0.24,0.238,0.272,0.284,0.318,0.278,0.266,0.281,0.261,0.248,0.186,0.175,0.189,0.168,0.167,0.158,0.118,0.081,0.134,0.164,0.225,0.255,0.247,0.258,0.025,0.175,0.169,0.265,0.258,0.257,0.278,0.258,0.257,0.274,0.107,0.192,0.157,0.126,0.145,0.183,0.201,0.167,0.227,0.22,0.217,0.214,0.226,0.224,0.219,0.221,0.224,0.222,0.221,0.245,0.158,0.224,0.235,0.247,0.238,0.235,0.237,0.221,0.232,0.231,0.218,0.19,0.239,0.204,0.257,0.237,0.211,0.24,0.239,0.283,0.212,0.305,0.1,-0.012,0.179,0.311,0.193,0.194,0.181,0.197,0.13,0.129,0.271,0.204,2638,Binding,GCN4_YEAST,Low,Eukaryote
GDIA_HUMAN_Silverstein_2021,0.442,0.429,0.439,0.446,0.451,0.452,0.205,0.398,0.466,0.462,0.391,0.423,0.46,0.159,0.247,0.448,0.397,0.356,0.411,0.401,0.253,0.385,0.38,0.409,0.326,0.439,0.425,0.384,0.397,0.415,0.423,0.393,0.47,0.276,0.321,0.394,0.356,0.432,0.448,0.437,0.451,0.47,0.461,0.233,0.121,0.432,0.26,0.357,0.421,0.387,0.101,0.389,0.335,0.402,0.378,0.391,0.399,0.377,0.391,0.375,0.405,0.461,0.338,0.49,0.292,0.306,0.307,0.336,0.393,0.406,0.353,0.423,0.436,0.431,0.411,0.47,0.405,0.46,0.464,0.437,0.458,0.472,0.447,0.435,0.426,0.404,0.323,0.053,0.355,0.265,0.321,0.405,0.39,0.406,0.356,0.481,0.462,1154,OrganismalFitness,GDIA_HUMAN,Low,Human
GFP_AEQVI_Sarkisyan_2016,0.649,0.644,0.672,0.673,0.679,0.679,0.049,0.635,0.667,0.661,0.524,0.098,0.103,0.078,0.131,0.103,0.108,0.149,0.29,0.598,0.078,0.105,0.181,0.098,0.046,0.188,0.298,0.642,0.647,0.678,0.607,0.615,0.62,0.074,0.066,0.182,0.629,0.649,0.651,0.672,0.683,0.685,0.706,0.024,-0.014,0.041,0.036,0.512,0.508,0.713,0.602,0.591,0.6,0.61,0.617,0.609,0.611,0.605,0.606,0.587,0.607,0.623,0.449,0.714,0.399,0.657,0.692,0.677,0.705,0.687,0.71,0.706,0.695,0.737,0.571,0.707,0.653,0.735,0.664,0.697,0.118,0.13,0.105,0.1,0.131,0.028,-0.165,-0.097,0.602,0.091,0.139,0.154,0.366,0.631,0.632,0.696,,51714,Activity,GFP_AEQVI,Low,Eukaryote
GLPA_HUMAN_Elazar_2016,0.227,0.134,0.207,0.21,0.18,0.162,0.307,0.524,0.385,0.361,0.388,0.417,0.412,0.339,0.392,0.453,0.425,0.38,0.47,0.163,0.37,0.388,0.364,0.407,0.363,0.39,0.414,0.42,0.49,0.349,0.435,0.276,0.426,0.281,0.423,0.372,0.414,0.423,0.392,0.417,0.391,0.362,0.405,0.405,0.384,0.428,0.341,0.33,0.413,0.31,0.177,0.529,0.513,0.507,0.479,0.5,0.455,0.5,0.434,0.464,0.507,0.443,0.411,0.425,0.439,0.542,0.544,0.583,0.585,0.578,0.726,0.389,0.575,0.278,0.472,0.433,0.471,0.429,0.358,0.398,0.448,0.477,0.407,0.393,0.415,0.332,0.18,-0.261,0.368,0.342,0.363,0.381,0.327,0.35,0.36,0.552,0.427,245,Expression,GLPA_HUMAN,Low,Human
GRB2_HUMAN_Faure_2021,0.405,0.521,0.507,0.538,0.54,0.546,0.486,0.45,0.539,0.491,0.533,0.455,0.515,0.526,0.598,0.626,0.647,0.535,0.579,0.534,0.544,0.516,0.514,0.453,0.532,0.509,0.446,0.524,0.448,0.504,0.428,0.422,0.584,0.464,0.536,0.506,0.404,0.517,0.506,0.436,0.562,0.561,0.532,0.584,0.323,0.53,0.572,0.672,0.527,0.69,0.516,0.621,0.649,0.638,0.638,0.647,0.628,0.629,0.645,0.625,0.65,0.556,0.607,0.612,0.556,0.629,0.639,0.68,0.691,0.718,0.715,0.548,0.713,0.625,0.634,0.615,0.632,0.612,0.466,0.649,0.626,0.542,0.62,0.493,0.453,0.432,0.388,0.392,0.289,0.449,0.444,0.518,0.421,0.438,0.425,0.72,,63366,OrganismalFitness,GRB2_HUMAN,Medium,Human
HCP_LAMBD_Tsuboyama_2023_2L6Q,0.315,0.41,0.113,0.147,0.351,0.36,0.241,0.399,0.43,0.485,0.666,0.45,0.496,0.285,0.416,0.574,0.686,0.588,0.577,0.245,0.292,0.306,0.362,0.368,0.324,0.325,0.21,0.345,0.515,0.579,0.636,0.504,0.599,0.191,0.262,0.287,0.486,0.43,0.443,0.531,0.374,0.43,0.507,0.31,0.285,0.614,0.376,0.667,0.724,0.73,0.601,0.692,0.698,0.71,0.687,0.714,0.711,0.696,0.714,0.719,0.723,0.768,0.609,0.585,0.455,0.626,0.696,0.652,0.696,0.697,0.656,0.615,0.732,0.646,0.722,0.629,0.747,0.641,0.449,0.755,0.654,0.679,0.363,0.691,0.691,0.385,0.07,0.039,0.61,0.373,0.367,0.364,0.37,0.426,0.491,0.712,0.607,1040,Stability,HCP_LAMBD,Medium,Virus
HECD1_HUMAN_Tsuboyama_2023_3DKM,0.291,0.37,0.324,0.324,0.332,0.336,0.055,0.234,0.359,0.37,0.303,0.303,0.293,0.134,0.206,0.474,0.387,0.34,0.385,0.337,-0.024,0.232,0.302,0.264,0.16,0.294,0.308,0.247,0.214,0.312,0.332,0.307,0.25,0.103,0.135,0.101,0.229,0.327,0.298,0.353,0.327,0.341,0.359,0.089,0.038,0.433,0.138,0.252,0.26,0.38,0.321,0.368,0.408,0.345,0.392,0.411,0.436,0.442,0.428,0.451,0.417,0.414,0.219,0.37,0.265,0.494,0.338,0.268,0.217,0.262,0.361,0.345,0.313,0.339,0.347,0.347,0.401,0.376,0.336,0.291,0.406,0.403,0.262,0.395,0.359,0.309,0.33,0.103,0.298,0.184,0.204,0.133,0.265,0.205,0.22,0.42,0.404,5586,Stability,HECD1_HUMAN,Medium,Human
HEM3_HUMAN_Loggerenberg_2023,0.418,0.409,0.403,0.407,0.42,0.418,0.126,0.103,0.432,0.442,0.388,0.383,0.396,0.142,0.387,0.408,0.393,0.418,0.429,0.108,0.349,0.373,0.37,0.375,0.358,0.387,0.376,0.385,0.402,0.435,0.42,0.41,0.452,0.093,0.377,0.381,0.377,0.42,0.43,0.438,0.427,0.434,0.44,0.323,0.135,0.384,0.378,0.314,0.358,0.301,0.146,0.357,0.337,0.353,0.363,0.377,0.374,0.371,0.373,0.368,0.377,0.431,0.415,0.409,0.357,0.286,0.275,0.304,0.305,0.382,0.317,0.451,0.424,0.43,0.385,0.419,0.396,0.424,0.423,0.434,0.406,0.4,0.393,0.425,0.41,0.398,0.343,0.102,0.376,0.374,0.362,0.381,0.377,0.359,0.379,0.473,0.423,5689,Activity,HEM3_HUMAN,Medium,Human
HIS7_YEAST_Pokusaeva_2019,0.472,0.542,0.558,0.557,0.533,0.531,0.146,0.273,0.468,0.508,0.472,0.411,0.477,0.057,0.113,0.44,0.411,0.475,0.48,0.454,0.325,0.402,0.433,0.478,0.404,0.485,0.464,0.516,0.539,0.524,0.4,0.374,0.563,0.143,0.397,0.453,0.585,0.488,0.496,0.616,0.573,0.548,0.582,0.14,0.04,0.299,0.02,0.378,0.424,0.529,0.392,0.444,0.35,0.404,0.427,0.44,0.407,0.418,0.45,0.431,0.424,0.521,0.222,0.535,0.399,0.427,0.403,0.423,0.471,0.553,0.448,0.567,0.563,0.452,0.453,0.521,0.539,0.562,0.403,0.614,0.474,0.486,0.487,0.46,0.33,0.481,0.078,-0.047,0.426,0.442,0.43,0.457,0.407,0.511,0.483,0.603,,496137,OrganismalFitness,HIS7_YEAST,Medium,Eukaryote
HMDH_HUMAN_Jiang_2019,0.491,0.421,0.382,0.394,0.456,0.451,0.158,0.282,0.282,0.274,0.275,0.341,0.315,0.046,0.01,0.317,0.509,0.374,0.378,0.302,0.451,0.162,0.175,0.221,0.435,0.197,0.168,0.209,0.213,0.476,0.413,0.401,0.338,0.228,0.308,0.247,0.219,0.44,0.34,0.33,0.437,0.361,0.36,0.172,0.069,0.477,0.496,0.323,0.444,-0.184,0.105,0.493,0.492,0.486,0.498,0.489,0.492,0.48,0.5,0.485,0.499,0.529,0.438,0.445,0.419,0.059,0.138,0.152,0.141,0.322,0.166,0.474,0.388,0.476,0.503,0.498,0.494,0.493,0.467,0.433,0.489,0.434,0.376,0.281,0.25,0.215,0.388,0.085,-0.108,0.428,0.52,0.495,0.308,0.199,0.169,0.518,,16853,OrganismalFitness,HMDH_HUMAN,Low,Human
HSP82_YEAST_Cote-Hammarlof_2020_growth-H2O2,0.316,0.36,0.371,0.376,0.364,0.365,0.194,0.394,0.427,0.437,0.362,0.416,0.453,-0.073,0.071,0.234,0.257,0.309,0.293,0.02,0.374,0.398,0.399,0.386,0.338,0.366,0.411,0.415,0.42,0.397,0.436,0.395,0.343,0.225,0.34,0.34,0.34,0.363,0.362,0.361,0.382,0.381,0.381,0.01,-0.056,0.383,0.4,0.068,0.267,0.097,-0.015,0.241,0.257,0.243,0.258,0.255,0.243,0.269,0.25,0.236,0.256,0.367,0.301,0.385,0.321,0.115,0.12,0.134,0.166,0.227,0.155,0.358,0.27,0.211,0.261,0.34,0.219,0.321,0.362,0.31,0.383,0.415,0.377,0.403,0.394,0.361,0.252,0.022,0.388,0.307,0.334,0.341,0.387,0.387,0.369,0.367,,2252,OrganismalFitness,HSP82_YEAST,Medium,Eukaryote
HSP82_YEAST_Flynn_2019,0.349,0.367,0.398,0.409,0.401,0.401,0.159,0.347,0.417,0.406,0.367,0.392,0.417,0.018,0.094,0.174,0.283,0.359,0.37,0.391,0.384,0.397,0.389,0.407,0.398,0.419,0.423,0.397,0.434,0.425,0.454,0.441,0.419,0.194,0.38,0.394,0.392,0.403,0.415,0.411,0.418,0.427,0.424,0.133,-0.065,0.371,0.313,0.188,0.308,0.11,0.062,0.291,0.283,0.295,0.305,0.293,0.296,0.301,0.296,0.282,0.302,0.386,0.329,0.345,0.326,0.162,0.204,0.234,0.217,0.339,0.208,0.424,0.371,0.365,0.303,0.383,0.289,0.376,0.42,0.349,0.375,0.387,0.393,0.406,0.415,0.353,0.305,-0.078,0.329,0.381,0.402,0.42,0.421,0.413,0.407,0.421,,13294,OrganismalFitness,HSP82_YEAST,Medium,Eukaryote
HSP82_YEAST_Mishra_2016,0.487,0.461,0.541,0.553,0.543,0.543,0.385,0.399,0.472,0.49,0.491,0.547,0.556,0.178,0.291,0.372,0.461,0.473,0.429,0.485,0.501,0.504,0.494,0.528,0.532,0.51,0.54,0.479,0.515,0.557,0.558,0.55,0.545,0.338,0.496,0.51,0.505,0.525,0.534,0.528,0.552,0.558,0.552,0.495,-0.104,0.485,0.533,0.105,0.352,0.096,0.04,0.433,0.416,0.417,0.446,0.442,0.44,0.451,0.46,0.436,0.45,0.458,0.445,0.477,0.462,0.179,0.259,0.286,0.242,0.427,0.242,0.547,0.466,0.458,0.446,0.525,0.429,0.519,0.547,0.388,0.493,0.48,0.537,0.526,0.496,0.415,0.406,-0.107,0.498,0.522,0.547,0.52,0.567,0.539,0.528,0.484,,4323,OrganismalFitness,HSP82_YEAST,Medium,Eukaryote
HXK4_HUMAN_Gersing_2022_activity,0.489,0.516,0.477,0.49,0.484,0.492,0.229,0.387,0.511,0.527,0.446,0.464,0.491,0.183,0.292,0.51,0.517,0.508,0.476,0.051,0.453,0.449,0.442,0.421,0.449,0.465,0.452,0.448,0.402,0.503,0.492,0.45,0.502,0.179,0.472,0.426,0.37,0.503,0.482,0.446,0.513,0.508,0.493,0.316,0.032,0.501,0.478,0.356,0.439,0.394,0.168,0.507,0.499,0.488,0.497,0.498,0.509,0.502,0.511,0.508,0.513,0.52,0.481,0.514,0.322,0.247,0.322,0.311,0.313,0.48,0.339,0.509,0.507,0.511,0.506,0.522,0.504,0.522,0.493,0.475,0.504,0.519,0.514,0.487,0.505,0.42,0.329,0.047,0.411,0.368,0.431,0.469,0.416,0.421,0.4,0.507,,8570,OrganismalFitness,HXK4_HUMAN,Medium,Human
HXK4_HUMAN_Gersing_2023_abundance,0.322,0.362,0.325,0.351,0.341,0.348,0.057,0.329,0.386,0.407,0.338,0.331,0.354,0.136,0.185,0.328,0.367,0.376,0.358,0.401,0.282,0.29,0.314,0.316,0.285,0.307,0.316,0.315,0.32,0.374,0.295,0.253,0.357,0.17,0.305,0.304,0.317,0.34,0.349,0.359,0.348,0.362,0.369,0.168,0.071,0.351,0.336,0.399,0.382,0.391,0.16,0.359,0.374,0.371,0.368,0.379,0.376,0.375,0.368,0.371,0.378,0.424,0.329,0.399,0.281,0.289,0.325,0.313,0.329,0.398,0.363,0.384,0.399,0.344,0.391,0.388,0.4,0.393,0.353,0.419,0.395,0.396,0.393,0.342,0.34,0.272,0.23,0.043,0.279,0.153,0.238,0.271,0.293,0.297,0.315,0.409,,8396,Expression,HXK4_HUMAN,Medium,Human
I6TAH8_I68A0_Doud_2015,0.347,0.317,0.268,0.264,0.364,0.361,-0.005,0.297,0.299,0.336,0.013,0.018,0.014,0.018,0.025,0.01,0.02,0.013,0.094,0.212,0.308,0.328,0.374,0.377,0.004,0.011,0.097,0.002,0.302,0.368,0.25,0.253,0.225,0.171,0.304,0.332,0.337,0.329,0.354,0.348,0.383,0.399,0.401,0.007,0.02,0.016,0.019,0.209,0.209,0.231,0.1,0.075,0.114,0.126,0.135,0.111,0.106,0.089,0.098,0.067,0.109,0.056,0.018,0.368,0.059,0.241,0.231,0.237,0.235,0.271,0.26,0.377,0.297,0.248,0.14,0.335,0.171,0.351,0.401,0.184,0.006,0.023,0.018,0.02,0.013,0.052,0.021,0.029,0.2,0.319,0.319,0.321,0.344,0.347,0.342,0.361,,9462,OrganismalFitness,I6TAH8_I68A0,Medium,Virus
IF1_ECOLI_Kelsic_2016,0.328,0.499,0.541,0.539,0.527,0.537,0.177,0.387,0.261,0.255,0.534,0.54,0.565,0.193,0.477,0.55,0.599,0.556,0.515,0.49,0.361,0.438,0.366,0.411,0.451,0.458,0.482,0.443,0.459,0.401,0.52,0.463,0.564,0.238,0.458,0.477,0.527,0.463,0.47,0.495,0.529,0.532,0.539,0.371,0.15,0.562,0.516,0.321,0.518,0.475,0.244,0.545,0.534,0.555,0.575,0.577,0.559,0.551,0.571,0.56,0.583,0.616,0.506,0.606,0.523,0.481,0.512,0.534,0.514,0.436,0.468,0.479,0.423,0.392,0.565,0.578,0.593,0.592,0.373,0.58,0.549,0.585,0.511,0.502,0.535,0.44,0.221,-0.04,0.503,0.513,0.483,0.471,0.469,0.484,0.481,0.526,0.572,1367,OrganismalFitness,IF1_ECOLI,High,Prokaryote
ILF3_HUMAN_Tsuboyama_2023_2L33,0.233,0.336,0.444,0.438,0.437,0.436,0.022,0.315,0.371,0.416,0.353,0.352,0.35,0.192,0.324,0.435,0.318,0.282,0.167,0.48,0.206,0.214,0.257,0.312,0.347,0.233,0.372,0.255,0.259,0.457,0.349,0.313,0.421,0.097,0.127,0.282,0.362,0.282,0.349,0.401,0.382,0.389,0.445,0.279,0.045,0.339,0.395,0.418,0.368,0.475,0.342,0.304,0.274,0.343,0.33,0.37,0.395,0.33,0.312,0.414,0.37,0.319,0.349,0.487,0.272,0.477,0.448,0.45,0.443,0.526,0.467,0.512,0.519,0.422,0.364,0.446,0.365,0.448,0.286,0.5,0.394,0.416,0.223,0.171,0.29,0.273,0.194,0.081,0.171,0.18,0.21,0.219,0.296,0.327,0.338,0.545,0.399,1329,Stability,ILF3_HUMAN,High,Human
ISDH_STAAW_Tsuboyama_2023_2LHR,0.094,0.101,0.206,0.197,0.231,0.231,0.326,0.128,0.326,0.356,0.453,0.413,0.434,0.377,0.394,0.449,0.429,0.479,0.45,0.185,0.326,0.199,0.218,0.228,0.318,0.335,0.329,0.298,0.36,0.304,0.396,0.334,0.39,0.236,0.291,0.249,0.298,0.259,0.219,0.245,0.263,0.221,0.244,0.3,0.248,0.349,0.329,0.592,0.526,0.519,0.49,0.42,0.407,0.429,0.428,0.427,0.429,0.409,0.414,0.419,0.426,0.608,0.522,0.295,0.401,0.61,0.698,0.63,0.688,0.589,0.619,0.361,0.576,0.406,0.514,0.396,0.569,0.435,0.255,0.638,0.471,0.463,0.403,0.423,0.439,0.322,0.25,0.145,0.434,0.346,0.348,0.321,0.407,0.251,0.413,0.493,0.33,1944,Stability,ISDH_STAAW,High,Prokaryote
KCNE1_HUMAN_Muhammad_2023_expression,0.13,0.116,0.093,0.128,0.124,0.103,0.209,0.024,0.041,0.053,0.187,0.159,0.134,0.163,0.177,0.129,0.106,0.062,0.073,0.116,0.181,0.183,0.092,0.039,0.191,0.111,0.108,0.055,0.046,0.096,0.089,0.057,0.093,-0.17,0.147,0.225,0.097,0.138,0.152,0.115,0.138,0.141,0.121,0.199,0.166,0.093,0.194,0.179,0.116,0.139,0.086,0.088,0.087,0.091,0.071,0.067,0.065,0.105,0.1,0.082,0.086,0.11,0.193,0.079,0.203,0.22,0.243,0.241,0.277,0.288,0.26,0.081,0.258,0.081,0.091,0.1,0.083,0.094,0.115,0.146,0.076,0.077,0.109,0.047,0.047,0.025,0.027,-0.034,0.065,0.159,0.151,0.26,0.17,0.177,0.163,0.188,,2339,Expression,KCNE1_HUMAN,Medium,Human
KCNE1_HUMAN_Muhammad_2023_function,0.417,0.498,0.479,0.496,0.479,0.514,0.215,0.52,0.514,0.52,0.368,0.474,0.584,0.209,0.162,0.599,0.525,0.465,0.38,0.241,0.272,0.293,0.448,0.539,0.285,0.614,0.58,0.603,0.575,0.488,0.568,0.475,0.585,-0.034,0.189,0.376,0.616,0.464,0.5,0.618,0.524,0.551,0.634,0.212,0.208,0.528,0.198,0.202,0.425,0.182,0.093,0.54,0.54,0.523,0.528,0.537,0.513,0.548,0.545,0.548,0.554,0.642,0.238,0.567,0.276,0.352,0.332,0.293,0.301,0.338,0.315,0.507,0.475,0.428,0.53,0.559,0.525,0.557,0.51,0.197,0.607,0.564,0.169,0.588,0.557,0.482,0.036,-0.132,0.514,0.251,0.174,0.207,0.384,0.315,0.641,0.443,,2315,Activity,KCNE1_HUMAN,Medium,Human
KCNH2_HUMAN_Kozek_2020,0.449,0.421,0.298,0.292,0.211,0.21,0.454,0.151,0.303,0.306,0.307,0.216,0.234,0.253,0.197,0.229,0.28,0.258,0.248,0.382,0.468,0.513,0.495,0.463,0.502,0.491,0.455,0.477,0.481,0.46,0.433,0.318,0.528,0.344,0.471,0.525,0.511,0.499,0.554,0.538,0.472,0.517,0.509,0.394,0.223,0.193,0.291,0.219,-0.079,-0.202,0.086,0.53,0.39,0.481,0.435,0.444,0.442,0.476,0.441,0.435,0.475,0.271,0.411,0.494,0.424,0.695,0.66,0.673,0.753,0.684,0.719,0.485,0.669,0.363,0.435,0.325,0.435,0.329,0.269,0.377,0.446,0.401,0.071,0.239,0.269,0.495,0.534,0.432,0.159,0.504,0.517,0.51,0.512,0.52,0.54,0.383,0.535,200,Activity,KCNH2_HUMAN,Medium,Human
KCNJ2_MOUSE_Coyote-Maestas_2022_function,0.256,0.329,0.334,0.344,0.347,0.353,0.059,0.238,0.315,0.309,0.37,0.348,0.361,0.058,0.289,0.379,0.382,0.385,0.388,0.161,0.345,0.305,0.252,0.241,0.351,0.335,0.316,0.345,0.224,0.372,0.366,0.352,0.366,0.148,0.327,0.294,0.235,0.35,0.329,0.289,0.364,0.354,0.335,0.213,-0.022,0.328,0.343,0.189,0.286,0.227,0.084,0.374,0.355,0.365,0.365,0.369,0.361,0.371,0.365,0.365,0.373,0.371,0.266,0.37,0.257,0.087,0.134,0.164,0.159,0.221,0.194,0.372,0.297,0.341,0.381,0.385,0.372,0.38,0.358,0.311,0.365,0.383,0.362,0.345,0.33,0.285,0.224,0.123,0.334,0.259,0.326,0.324,0.344,0.312,0.258,0.336,,6963,Activity,KCNJ2_MOUSE,Medium,Eukaryote
KCNJ2_MOUSE_Coyote-Maestas_2022_surface,0.381,0.341,0.254,0.265,0.338,0.34,0.119,0.224,0.28,0.277,0.323,0.287,0.297,0.176,0.36,0.37,0.352,0.343,0.354,0.218,0.239,0.228,0.217,0.245,0.265,0.265,0.26,0.273,0.251,0.368,0.284,0.255,0.333,0.174,0.243,0.252,0.235,0.324,0.331,0.33,0.328,0.338,0.34,0.266,0.065,0.263,0.309,0.305,0.262,0.306,0.167,0.322,0.311,0.33,0.32,0.339,0.321,0.343,0.321,0.317,0.334,0.351,0.349,0.372,0.289,0.226,0.311,0.295,0.318,0.371,0.357,0.357,0.386,0.342,0.342,0.357,0.353,0.362,0.333,0.34,0.329,0.31,0.317,0.293,0.257,0.25,0.214,0.15,0.265,0.27,0.302,0.295,0.26,0.252,0.249,0.392,,6917,Expression,KCNJ2_MOUSE,Medium,Eukaryote
KKA2_KLEPN_Melnikov_2014,0.25,0.53,0.437,0.622,0.599,0.603,0.199,0.423,0.538,0.606,0.566,0.597,0.621,0.212,0.261,0.487,0.601,0.645,0.662,0.498,0.285,0.42,0.518,0.54,0.353,0.578,0.577,0.568,0.638,0.627,0.637,0.586,0.652,0.148,0.243,0.485,0.586,0.445,0.524,0.588,0.586,0.609,0.63,0.253,0.076,0.559,0.386,0.456,0.582,0.551,0.267,0.587,0.572,0.588,0.578,0.579,0.59,0.574,0.583,0.591,0.599,0.641,0.329,0.648,0.173,0.467,0.529,0.547,0.569,0.55,0.57,0.65,0.54,0.663,0.597,0.644,0.61,0.654,0.487,0.628,0.653,0.649,0.552,0.631,0.651,0.476,0.339,0.054,0.666,0.33,0.451,0.537,0.601,0.627,0.618,0.687,,4960,OrganismalFitness,KKA2_KLEPN,High,Prokaryote
LGK_LIPST_Klesmith_2015,0.28,0.426,0.485,0.494,0.481,0.498,0.104,0.465,0.467,0.559,0.444,0.537,0.564,0.179,0.327,0.382,0.515,0.58,0.578,0.499,0.276,0.396,0.462,0.495,0.365,0.492,0.525,0.479,0.552,0.542,0.537,0.46,0.567,0.139,0.307,0.398,0.555,0.37,0.404,0.527,0.482,0.495,0.54,0.176,0.051,0.483,0.367,0.398,0.507,0.492,0.145,0.51,0.505,0.511,0.51,0.513,0.52,0.518,0.517,0.52,0.527,0.411,0.334,0.46,0.276,0.326,0.356,0.344,0.386,0.455,0.394,0.55,0.474,0.516,0.52,0.547,0.533,0.554,0.462,0.435,0.418,0.409,0.39,0.568,0.542,0.469,0.237,0.007,0.597,0.326,0.346,0.412,0.449,0.464,0.499,0.599,,7890,Activity,LGK_LIPST,Medium,Eukaryote
LYAM1_HUMAN_Elazar_2016,0.314,0.303,0.189,0.158,0.258,0.266,0.361,0.172,0.413,0.416,0.436,0.37,0.371,0.307,0.363,0.336,0.31,0.426,0.454,0.336,0.382,0.391,0.386,0.385,0.362,0.369,0.373,0.298,0.339,0.349,0.313,0.179,0.48,0.203,0.353,0.437,0.343,0.362,0.41,0.348,0.343,0.372,0.313,0.307,0.346,0.318,0.35,0.17,0.259,0.163,0.103,0.235,0.317,0.398,0.33,0.279,0.295,0.352,0.348,0.272,0.332,0.419,0.39,0.364,0.407,0.477,0.546,0.519,0.475,0.467,0.601,0.459,0.468,0.324,0.374,0.354,0.428,0.386,0.278,0.278,0.324,0.341,0.338,0.224,0.308,0.3,0.282,0.157,0.479,0.302,0.325,0.402,0.232,0.395,0.381,0.531,0.444,359,Expression,LYAM1_HUMAN,Medium,Human
MAFG_MOUSE_Tsuboyama_2023_1K1V,0.613,0.636,0.633,0.635,0.621,0.623,0.405,0.643,0.633,0.626,0.619,0.355,0.6,0.453,0.429,0.471,0.48,0.551,0.413,0.627,0.448,0.494,0.522,0.566,0.46,0.515,0.447,0.536,0.49,0.602,0.621,0.609,0.679,0.392,0.329,0.565,0.509,0.589,0.647,0.657,0.629,0.661,0.683,0.312,0.079,0.425,0.246,0.596,0.327,0.638,0.611,0.646,0.615,0.617,0.638,0.623,0.638,0.636,0.642,0.651,0.639,0.719,0.727,0.619,0.31,0.688,0.832,0.826,0.805,0.802,0.795,0.662,0.766,0.685,0.316,0.646,0.401,0.68,0.576,0.735,0.549,0.613,0.449,0.593,0.398,0.398,0.454,-0.099,0.531,0.284,0.56,0.618,0.405,0.482,0.528,0.737,0.635,1429,Stability,MAFG_MOUSE,Medium,Eukaryote
MBD11_ARATH_Tsuboyama_2023_6ACV,0.551,0.723,0.708,0.727,0.758,0.763,-0.058,0.572,0.658,0.744,0.727,0.422,0.512,-0.146,0.025,0.742,0.699,0.685,0.74,0.715,-0.032,0.058,0.576,0.615,0.193,0.561,0.537,0.568,0.714,0.748,0.729,0.67,0.736,0.649,-0.282,0.063,0.033,0.586,0.658,0.634,0.729,0.751,0.742,-0.064,-0.203,0.629,0.433,0.521,0.66,0.773,0.576,0.793,0.76,0.792,0.745,0.758,0.741,0.763,0.776,0.774,0.78,0.813,0.72,0.754,0.434,0.706,0.774,0.772,0.772,0.791,0.803,0.771,0.802,0.781,0.7,0.79,0.684,0.794,0.729,0.76,0.786,0.714,0.679,0.765,0.676,0.186,0.272,0.034,0.777,-0.081,0.04,-0.089,0.079,0.323,0.44,0.82,,2116,Stability,MBD11_ARATH,Medium,Eukaryote
MET_HUMAN_Estevam_2023,0.454,0.544,0.538,0.563,0.582,0.584,0.517,0.52,0.55,0.562,0.585,0.55,0.562,0.452,0.515,0.542,0.59,0.596,0.599,0.583,0.526,0.506,0.466,0.492,0.53,0.519,0.519,0.488,0.454,0.548,0.57,0.53,0.58,0.286,0.471,0.501,0.525,0.512,0.539,0.563,0.558,0.565,0.573,0.542,0.347,0.571,0.575,0.35,0.42,0.498,0.192,0.54,0.548,0.548,0.55,0.562,0.554,0.557,0.561,0.556,0.566,0.575,0.529,0.557,0.445,0.449,0.504,0.514,0.537,0.586,0.54,0.584,0.585,0.522,0.567,0.594,0.574,0.599,0.551,0.495,0.582,0.598,0.59,0.561,0.525,0.482,0.415,0.338,0.46,0.449,0.499,0.499,0.529,0.523,0.5,0.544,0.597,5393,Activity,MET_HUMAN,Medium,Human
MK01_HUMAN_Brenan_2016,0.176,0.198,0.237,0.241,0.223,0.227,0.209,0.163,0.198,0.184,0.033,0.167,0.182,0.17,0.199,0.195,0.178,0.189,0.141,0.184,0.209,0.117,0.069,0.016,0.183,0.089,0.057,0.076,-0.067,0.218,0.176,0.222,0.18,0.106,0.169,0.058,0.004,0.193,0.119,0.093,0.227,0.205,0.202,0.196,0.125,0.135,0.184,0.059,-0.0,0.133,0.006,0.161,0.162,0.148,0.166,0.17,0.163,0.163,0.169,0.177,0.171,0.15,0.186,0.193,0.183,0.167,0.166,0.181,0.201,0.213,0.165,0.228,0.226,0.217,0.159,0.199,0.174,0.208,0.183,0.148,0.196,0.158,0.125,0.056,0.028,0.135,0.091,0.16,-0.085,0.218,0.203,0.23,0.18,0.112,0.067,0.232,0.209,6809,OrganismalFitness,MK01_HUMAN,Medium,Human
MLAC_ECOLI_MacRae_2023,0.225,0.352,0.419,0.424,0.409,0.411,-0.014,0.36,0.412,0.419,0.399,0.416,0.432,-0.011,0.236,0.273,0.382,0.382,0.412,0.387,0.078,0.366,0.38,0.402,0.313,0.383,0.392,0.382,0.424,0.4,0.44,0.41,0.39,0.039,0.131,0.315,0.296,0.265,0.327,0.315,0.374,0.396,0.395,0.177,-0.036,0.329,0.235,0.006,0.193,0.123,-0.026,0.319,0.28,0.288,0.293,0.315,0.308,0.295,0.305,0.332,0.313,0.23,0.203,0.427,0.076,0.244,0.241,0.315,0.303,0.329,0.309,0.369,0.354,0.303,0.335,0.404,0.333,0.405,0.33,0.163,0.377,0.434,0.336,0.362,0.399,0.329,0.22,-0.077,0.384,0.35,0.366,0.337,0.336,0.339,0.308,0.4,0.384,4007,OrganismalFitness,MLAC_ECOLI,Medium,Prokaryote
MSH2_HUMAN_Jia_2020,0.352,0.399,0.367,0.376,0.383,0.39,0.204,0.339,0.395,0.402,0.349,0.38,0.4,0.213,0.349,0.397,0.339,0.296,0.204,0.364,0.296,0.31,0.264,0.257,0.326,0.317,0.32,0.326,0.301,0.394,0.351,0.324,0.396,0.208,0.277,0.351,0.281,0.35,0.388,0.346,0.387,0.405,0.383,0.284,0.103,0.4,0.355,0.293,0.363,0.062,0.099,0.305,0.279,0.291,0.309,0.317,0.3,0.295,0.308,0.339,0.321,0.394,0.366,0.378,0.348,0.231,0.267,0.276,0.296,0.356,0.288,0.409,0.38,0.376,0.341,0.396,0.354,0.399,0.347,0.389,0.385,0.39,0.368,0.369,0.355,0.246,0.212,0.046,0.134,0.285,0.27,0.325,0.355,0.336,0.299,0.363,0.378,16749,OrganismalFitness,MSH2_HUMAN,Medium,Human
MTH3_HAEAE_RockahShmuel_2015,0.371,0.612,0.709,0.718,0.696,0.704,0.314,0.644,0.673,0.688,0.581,0.692,0.708,0.19,0.352,0.405,0.527,0.608,0.644,0.658,0.311,0.454,0.6,0.662,0.488,0.663,0.711,0.684,0.727,0.679,0.697,0.652,0.646,0.291,0.353,0.495,0.665,0.422,0.496,0.638,0.657,0.679,0.714,0.324,-0.031,0.477,0.341,0.449,0.574,0.583,0.225,0.544,0.531,0.559,0.569,0.561,0.573,0.551,0.571,0.557,0.572,0.58,0.378,0.666,0.176,0.384,0.393,0.443,0.439,0.531,0.46,0.681,0.55,0.638,0.552,0.687,0.572,0.697,0.527,0.572,0.643,0.664,0.637,0.743,0.729,0.622,0.486,-0.009,0.753,0.595,0.654,0.674,0.682,0.716,0.722,0.726,0.732,1777,OrganismalFitness,MTH3_HAEAE,Medium,Prokaryote
MTHR_HUMAN_Weile_2021,0.25,0.271,0.249,0.257,0.258,0.257,0.205,0.194,0.292,0.293,0.387,0.299,0.32,0.169,0.414,0.482,0.348,0.276,0.285,0.253,0.443,0.162,0.217,0.265,0.437,0.239,0.264,0.245,0.295,0.296,0.22,0.189,0.321,0.143,0.451,0.307,0.212,0.378,0.315,0.254,0.363,0.309,0.269,0.278,0.111,0.379,0.411,0.239,0.338,0.377,0.092,0.324,0.289,0.299,0.297,0.305,0.316,0.335,0.319,0.347,0.325,0.332,0.376,0.303,0.217,0.274,0.252,0.285,0.284,0.385,0.27,0.294,0.377,0.27,0.332,0.313,0.323,0.308,0.289,0.378,0.477,0.326,0.508,0.308,0.304,0.252,0.18,0.112,0.32,0.435,0.452,0.393,0.283,0.222,0.27,0.353,0.334,12464,OrganismalFitness,MTHR_HUMAN,Low,Human
MYO3_YEAST_Tsuboyama_2023_2BTT,0.143,0.248,0.334,0.362,0.381,0.412,0.155,0.251,0.428,0.419,0.519,0.482,0.478,0.171,0.411,0.583,0.588,0.507,0.247,0.321,0.351,0.247,0.336,0.311,0.342,0.287,0.364,0.313,0.336,0.283,0.279,0.178,0.37,0.126,0.419,0.332,0.282,0.382,0.329,0.292,0.411,0.401,0.382,0.112,0.045,0.431,0.294,0.392,0.427,0.479,0.359,0.517,0.495,0.545,0.512,0.525,0.529,0.513,0.519,0.506,0.525,0.571,0.5,0.504,0.3,0.408,0.503,0.575,0.589,0.688,0.585,0.284,0.641,0.276,0.522,0.491,0.51,0.486,0.228,0.534,0.63,0.618,0.471,0.517,0.55,0.362,0.225,0.177,0.5,0.178,0.249,0.199,0.326,0.209,0.269,0.542,0.467,3297,Stability,MYO3_YEAST,High,Eukaryote
NCAP_I34A1_Doud_2015,0.364,0.328,0.334,0.333,0.363,0.364,0.002,0.335,0.373,0.348,0.015,0.019,0.02,0.023,0.026,0.02,0.028,0.031,0.107,0.269,0.352,0.382,0.408,0.413,0.018,0.042,0.108,0.03,0.352,0.377,0.27,0.279,0.278,0.126,0.356,0.373,0.415,0.39,0.402,0.424,0.425,0.426,0.441,0.019,0.015,0.027,0.025,0.259,0.27,0.278,0.123,0.129,0.171,0.166,0.184,0.172,0.172,0.155,0.163,0.129,0.171,0.135,0.081,0.436,0.107,0.239,0.27,0.23,0.259,0.283,0.267,0.407,0.308,0.255,0.196,0.377,0.233,0.396,0.424,0.249,0.021,0.029,0.026,0.038,0.029,0.061,0.06,0.0,0.252,0.314,0.314,0.34,0.359,0.359,0.384,0.383,0.419,9462,OrganismalFitness,NCAP_I34A1,Medium,Virus
NKX31_HUMAN_Tsuboyama_2023_2L9R,0.428,0.548,0.586,0.584,0.607,0.619,0.582,0.553,0.584,0.608,0.56,0.568,0.572,0.627,0.638,0.674,0.651,0.582,0.602,0.558,0.564,0.557,0.556,0.564,0.576,0.579,0.606,0.54,0.577,0.64,0.525,0.506,0.619,0.551,0.494,0.565,0.577,0.578,0.624,0.628,0.601,0.618,0.621,0.454,0.395,0.342,0.408,0.589,0.401,0.643,0.642,0.634,0.626,0.639,0.648,0.669,0.641,0.635,0.629,0.642,0.645,0.566,0.596,0.618,0.456,0.704,0.673,0.669,0.586,0.655,0.706,0.66,0.654,0.597,0.608,0.641,0.623,0.646,0.591,0.633,0.54,0.556,0.543,0.534,0.55,0.499,0.338,0.45,0.521,0.537,0.637,0.641,0.593,0.56,0.542,0.704,0.566,2482,Stability,NKX31_HUMAN,High,Human
NPC1_HUMAN_Erwood_2022_HEK293T,0.683,0.7,0.627,0.632,0.7,0.7,0.22,0.529,0.739,0.734,0.701,0.325,0.458,0.221,0.394,0.614,0.694,0.721,0.719,0.147,0.197,0.46,0.412,0.419,0.421,0.491,0.631,0.447,0.495,0.71,0.659,0.548,0.65,0.095,0.231,0.547,0.579,0.639,0.675,0.696,0.691,0.708,0.722,0.3,0.134,0.702,0.568,0.499,0.683,0.06,0.211,0.681,0.664,0.687,0.679,0.678,0.664,0.693,0.701,0.685,0.697,0.7,0.392,0.698,0.263,0.514,0.509,0.467,0.507,0.668,0.52,0.73,0.711,0.685,0.669,0.717,0.688,0.726,0.715,0.584,0.654,0.697,0.652,0.681,0.687,0.537,0.374,-0.068,0.433,0.205,0.345,0.362,0.554,0.64,0.579,0.737,0.722,637,Activity,NPC1_HUMAN,Low,Human
NPC1_HUMAN_Erwood_2022_RPE1,0.779,0.688,0.534,0.554,0.716,0.731,0.417,0.535,0.584,0.707,0.704,0.298,0.357,0.314,0.394,0.629,0.661,0.64,0.709,0.405,0.631,0.49,0.543,0.417,0.408,0.468,0.536,0.373,0.531,0.633,0.74,0.568,0.748,0.475,0.466,0.377,0.612,0.787,0.672,0.774,0.783,0.7,0.751,0.506,0.442,0.786,0.391,0.472,0.557,-0.107,0.157,0.574,0.537,0.559,0.482,0.569,0.56,0.571,0.646,0.64,0.595,0.692,0.482,0.778,0.235,0.792,0.84,0.79,0.806,0.777,0.839,0.654,0.808,0.752,0.547,0.682,0.508,0.662,0.757,0.273,0.65,0.574,0.619,0.724,0.49,0.508,0.165,0.237,0.43,0.207,0.291,0.453,0.579,0.667,0.423,0.761,0.788,63,Activity,NPC1_HUMAN,Low,Human
NRAM_I33A0_Jiang_2016,0.569,0.565,0.501,0.49,0.584,0.584,0.035,0.39,0.625,0.638,-0.076,0.162,0.448,-0.075,-0.098,0.005,0.161,0.541,0.575,0.343,0.583,0.633,0.584,0.571,0.047,0.53,0.627,0.462,0.654,0.635,0.404,0.441,0.608,-0.169,0.512,0.532,0.551,0.592,0.615,0.621,0.628,0.638,0.632,-0.105,-0.127,-0.111,-0.111,0.422,0.414,0.448,0.178,0.19,0.228,0.235,0.297,0.253,0.29,0.263,0.247,0.199,0.254,0.292,0.145,0.666,-0.07,0.488,0.59,0.629,0.631,0.582,0.581,0.658,0.633,0.536,0.355,0.521,0.358,0.524,0.632,0.396,-0.064,-0.07,-0.087,-0.004,0.067,0.36,0.542,-0.122,0.49,0.587,0.621,0.641,0.634,0.668,0.631,0.562,0.68,298,OrganismalFitness,NRAM_I33A0,Medium,Virus
NUD15_HUMAN_Suiter_2020,0.271,0.453,0.564,0.596,0.591,0.594,-0.005,0.389,0.602,0.665,0.603,0.6,0.645,0.299,0.419,0.46,0.526,0.583,0.599,0.501,0.301,0.454,0.546,0.518,0.412,0.579,0.577,0.549,0.542,0.587,0.623,0.553,0.627,0.147,0.36,0.423,0.575,0.433,0.456,0.604,0.587,0.586,0.635,0.386,0.015,0.603,0.429,0.483,0.581,0.534,0.317,0.55,0.521,0.544,0.568,0.556,0.571,0.567,0.559,0.556,0.573,0.679,0.564,0.675,0.377,0.556,0.617,0.627,0.643,0.661,0.667,0.627,0.658,0.608,0.585,0.647,0.61,0.662,0.467,0.67,0.656,0.651,0.605,0.634,0.644,0.558,0.343,0.068,0.463,0.407,0.418,0.471,0.46,0.52,0.568,0.676,0.607,2844,Expression,NUD15_HUMAN,High,Human
NUSA_ECOLI_Tsuboyama_2023_1WCL,0.392,0.589,0.58,0.571,0.602,0.613,0.285,0.465,0.638,0.599,0.56,0.323,0.346,0.322,0.39,0.405,0.494,0.532,0.533,0.56,0.394,0.549,0.572,0.589,0.325,0.497,0.44,0.525,0.572,0.638,0.67,0.706,0.702,0.183,0.365,0.419,0.425,0.505,0.493,0.508,0.628,0.601,0.622,0.375,0.246,0.381,0.357,0.682,0.641,0.73,0.658,0.709,0.695,0.699,0.721,0.726,0.741,0.716,0.716,0.719,0.723,0.685,0.575,0.546,0.5,0.754,0.773,0.768,0.803,0.821,0.761,0.67,0.802,0.538,0.695,0.676,0.673,0.667,0.659,0.779,0.503,0.611,0.441,0.583,0.653,0.508,0.305,-0.205,0.575,0.395,0.35,0.396,0.327,0.325,0.489,0.776,0.637,2028,Stability,NUSA_ECOLI,High,Prokaryote
NUSG_MYCTU_Tsuboyama_2023_2MI6,0.405,0.404,0.417,0.431,0.451,0.434,0.23,0.423,0.485,0.461,0.398,0.361,0.421,0.389,0.561,0.51,0.518,0.525,0.477,0.521,0.264,0.339,0.315,0.347,0.38,0.385,0.461,0.334,0.378,0.502,0.394,0.387,0.499,0.321,0.269,0.275,0.372,0.395,0.399,0.426,0.413,0.417,0.424,0.445,0.144,0.395,0.531,0.676,0.56,0.759,0.64,0.487,0.457,0.454,0.507,0.487,0.485,0.485,0.486,0.483,0.488,0.41,0.588,0.515,0.5,0.632,0.705,0.697,0.719,0.688,0.662,0.536,0.681,0.54,0.572,0.515,0.585,0.529,0.41,0.584,0.442,0.426,0.388,0.325,0.301,0.548,0.396,-0.062,0.34,0.33,0.394,0.397,0.388,0.385,0.388,0.607,0.527,1380,Stability,NUSG_MYCTU,High,Prokaryote
OBSCN_HUMAN_Tsuboyama_2023_1V1C,0.54,0.697,0.759,0.777,0.745,0.757,0.384,0.455,0.751,0.763,0.691,0.735,0.759,0.392,0.779,0.819,0.797,0.786,0.755,0.723,0.688,0.689,0.663,0.687,0.589,0.667,0.694,0.726,0.604,0.735,0.694,0.679,0.696,0.549,0.262,0.461,0.575,0.687,0.695,0.704,0.755,0.76,0.764,0.543,0.115,0.507,0.633,0.63,0.54,0.782,0.747,0.762,0.76,0.761,0.755,0.772,0.76,0.773,0.767,0.776,0.771,0.825,0.772,0.764,0.572,0.782,0.806,0.759,0.747,0.793,0.754,0.773,0.772,0.775,0.802,0.802,0.824,0.812,0.643,0.806,0.82,0.818,0.643,0.661,0.695,0.663,0.395,0.146,0.603,0.473,0.394,0.476,0.425,0.55,0.643,0.839,0.756,3197,Stability,OBSCN_HUMAN,High,Human
ODP2_GEOSE_Tsuboyama_2023_1W4G,-0.211,-0.17,0.339,0.188,0.332,0.332,-0.149,0.093,0.175,0.19,0.064,-0.1,-0.115,-0.069,-0.151,0.14,0.221,0.089,0.21,0.233,0.189,0.174,0.159,0.177,0.171,0.195,0.166,0.192,0.233,0.327,0.062,0.023,0.068,0.245,-0.05,0.025,0.012,0.19,0.181,0.178,0.271,0.26,0.29,0.268,-0.07,0.339,0.327,0.452,0.424,0.437,0.322,0.118,0.075,0.085,0.129,0.073,0.127,0.114,0.116,0.094,0.107,0.286,0.171,0.035,0.065,0.266,0.362,0.378,0.39,0.198,0.339,0.27,0.254,0.388,0.317,0.353,0.322,0.36,-0.008,0.294,0.187,0.183,0.179,0.174,0.205,0.012,-0.015,0.058,-0.031,-0.094,0.092,0.071,0.186,0.146,0.198,0.362,0.081,1134,Stability,ODP2_GEOSE,High,Prokaryote
OPSD_HUMAN_Wan_2019,0.17,0.433,0.445,0.517,0.463,0.466,0.347,0.569,0.563,0.6,0.397,0.499,0.56,0.29,0.508,0.518,0.552,0.449,0.482,0.555,0.528,0.549,0.538,0.578,0.552,0.594,0.598,0.577,0.57,0.511,0.422,0.326,0.474,0.17,0.503,0.53,0.485,0.537,0.532,0.503,0.485,0.482,0.488,0.386,0.08,0.493,0.472,0.632,0.518,0.632,0.224,0.402,0.353,0.412,0.421,0.482,0.487,0.418,0.421,0.49,0.472,0.582,0.522,0.507,0.403,0.56,0.567,0.54,0.619,0.656,0.518,0.555,0.645,0.537,0.531,0.54,0.567,0.568,0.168,0.581,0.506,0.465,0.586,0.555,0.51,0.483,0.37,0.118,0.535,0.426,0.523,0.467,0.491,0.549,0.537,0.578,0.538,165,Expression,OPSD_HUMAN,High,Human
OTC_HUMAN_Lo_2023,0.524,0.564,0.484,0.522,0.55,0.552,0.127,0.404,0.59,0.592,0.546,0.573,0.581,0.142,0.411,0.512,0.531,0.51,0.534,0.565,0.453,0.461,0.522,0.545,0.476,0.555,0.526,0.54,0.574,0.599,0.475,0.409,0.58,0.085,0.429,0.511,0.569,0.522,0.57,0.614,0.567,0.584,0.599,0.279,0.092,0.524,0.463,0.649,0.606,0.674,0.364,0.526,0.547,0.544,0.574,0.556,0.567,0.56,0.548,0.541,0.564,0.616,0.49,0.533,0.464,0.414,0.46,0.487,0.5,0.62,0.497,0.622,0.646,0.54,0.593,0.615,0.61,0.621,0.513,0.665,0.524,0.583,0.528,0.59,0.557,0.449,0.431,-0.003,0.527,0.468,0.512,0.512,0.51,0.534,0.568,0.712,0.567,1570,Activity,OTC_HUMAN,Medium,Human
OTU7A_HUMAN_Tsuboyama_2023_2L2D,0.116,0.243,0.184,0.201,0.224,0.227,0.192,0.134,0.141,0.146,0.434,0.604,0.581,0.205,0.563,0.588,0.319,0.362,0.408,0.155,0.184,0.178,0.221,0.275,0.345,0.26,0.38,0.307,0.148,0.259,0.406,0.388,0.468,0.132,0.168,0.225,0.349,0.201,0.198,0.308,0.242,0.22,0.262,0.365,0.184,0.543,0.548,0.532,0.533,0.61,0.537,0.395,0.342,0.348,0.401,0.422,0.421,0.374,0.409,0.414,0.404,0.642,0.632,0.486,0.489,0.652,0.644,0.597,0.63,0.724,0.668,0.377,0.72,0.374,0.354,0.327,0.399,0.372,0.186,0.681,0.636,0.667,0.436,0.378,0.471,0.317,0.111,0.056,0.26,0.248,0.211,0.254,0.277,0.368,0.347,0.488,0.354,635,Stability,OTU7A_HUMAN,High,Human
OXDA_RHOTO_Vanella_2023_activity,0.104,0.292,0.364,0.373,0.356,0.356,0.195,0.251,0.278,0.285,0.383,0.348,0.359,0.122,0.219,0.326,0.37,0.39,0.401,0.259,0.125,0.214,0.303,0.305,0.219,0.343,0.356,0.329,0.407,0.378,0.429,0.408,0.466,0.102,0.164,0.213,0.293,0.267,0.275,0.305,0.342,0.344,0.355,0.153,0.014,0.369,0.247,0.295,0.386,0.361,0.139,0.367,0.36,0.355,0.361,0.365,0.374,0.367,0.376,0.358,0.377,0.396,0.242,0.363,0.083,0.2,0.208,0.195,0.208,0.355,0.229,0.438,0.353,0.417,0.362,0.387,0.376,0.395,0.317,0.336,0.359,0.378,0.345,0.357,0.359,0.261,0.085,0.144,0.405,0.16,0.18,0.255,0.283,0.324,0.353,0.413,0.393,6396,Activity,OXDA_RHOTO,High,Eukaryote
OXDA_RHOTO_Vanella_2023_expression,0.18,0.253,0.29,0.287,0.276,0.272,0.19,0.193,0.296,0.305,0.327,0.31,0.311,0.221,0.257,0.298,0.315,0.351,0.34,0.175,0.169,0.243,0.252,0.233,0.217,0.264,0.295,0.275,0.31,0.308,0.289,0.241,0.347,0.082,0.227,0.211,0.246,0.268,0.259,0.267,0.284,0.278,0.278,0.243,0.144,0.304,0.234,0.385,0.356,0.333,0.142,0.329,0.318,0.308,0.317,0.323,0.308,0.321,0.316,0.311,0.326,0.408,0.321,0.328,0.277,0.312,0.352,0.381,0.436,0.401,0.38,0.343,0.399,0.283,0.353,0.34,0.361,0.344,0.246,0.39,0.334,0.348,0.303,0.339,0.334,0.248,0.004,0.219,0.33,0.19,0.223,0.258,0.269,0.245,0.303,0.378,0.369,6769,Expression,OXDA_RHOTO,High,Eukaryote
P53_HUMAN_Giacomelli_2018_Null_Etoposide,0.415,0.424,0.329,0.344,0.432,0.427,-0.088,0.319,0.283,0.291,0.467,0.457,0.509,-0.154,-0.146,0.314,0.432,0.469,0.497,0.116,0.312,0.438,0.453,0.409,0.39,0.472,0.484,0.493,0.368,0.423,0.465,0.41,0.493,0.208,0.258,0.449,0.355,0.403,0.462,0.4,0.427,0.469,0.413,-0.151,-0.155,0.475,-0.051,0.389,0.471,0.414,0.186,0.449,0.45,0.451,0.45,0.452,0.47,0.448,0.454,0.452,0.464,0.477,0.186,0.457,0.126,0.388,0.431,0.468,0.493,0.425,0.5,0.445,0.471,0.482,0.444,0.475,0.446,0.478,0.424,0.275,0.463,0.46,0.452,0.458,0.442,0.399,0.289,-0.053,0.326,-0.114,-0.049,-0.117,0.235,0.453,0.417,0.444,0.331,7467,OrganismalFitness,P53_HUMAN,Low,Human
P53_HUMAN_Giacomelli_2018_Null_Nutlin,0.35,0.395,0.294,0.304,0.383,0.38,-0.087,0.269,0.287,0.289,0.482,0.447,0.498,-0.158,-0.145,0.29,0.404,0.431,0.459,0.126,0.294,0.447,0.463,0.43,0.375,0.487,0.5,0.523,0.329,0.42,0.45,0.375,0.454,0.213,0.239,0.453,0.36,0.354,0.431,0.379,0.372,0.43,0.383,-0.144,-0.153,0.471,-0.063,0.403,0.48,0.426,0.188,0.423,0.427,0.427,0.433,0.431,0.44,0.426,0.43,0.434,0.44,0.469,0.182,0.417,0.115,0.367,0.414,0.455,0.465,0.403,0.477,0.441,0.456,0.466,0.421,0.433,0.422,0.436,0.399,0.279,0.442,0.439,0.458,0.465,0.458,0.411,0.281,-0.009,0.316,-0.126,-0.062,-0.119,0.224,0.446,0.42,0.386,0.42,7467,OrganismalFitness,P53_HUMAN,Low,Human
P53_HUMAN_Giacomelli_2018_WT_Nutlin,0.445,0.462,0.342,0.366,0.479,0.481,-0.143,0.3,0.258,0.259,0.551,0.496,0.554,-0.194,-0.174,0.362,0.4,0.446,0.467,0.028,0.41,0.563,0.521,0.48,0.482,0.535,0.55,0.616,0.285,0.507,0.493,0.449,0.532,0.225,0.326,0.612,0.408,0.448,0.568,0.433,0.475,0.567,0.438,-0.185,-0.202,0.544,-0.08,0.452,0.553,0.461,0.223,0.438,0.45,0.449,0.452,0.461,0.471,0.437,0.461,0.438,0.463,0.482,0.166,0.441,0.072,0.365,0.423,0.506,0.533,0.387,0.536,0.529,0.471,0.596,0.431,0.484,0.426,0.485,0.511,0.267,0.484,0.477,0.507,0.501,0.509,0.452,0.351,-0.052,0.34,-0.147,-0.12,-0.163,0.341,0.568,0.473,0.5,0.443,7467,OrganismalFitness,P53_HUMAN,Low,Human
P53_HUMAN_Kotler_2018,0.629,0.588,0.496,0.556,0.555,0.576,0.109,0.498,0.573,0.585,0.6,0.538,0.622,0.095,0.108,0.628,0.678,0.698,0.702,0.432,0.429,0.461,0.478,0.463,0.47,0.48,0.465,0.47,0.493,0.593,0.631,0.585,0.652,0.039,0.398,0.468,0.42,0.611,0.584,0.564,0.604,0.588,0.581,0.09,0.04,0.638,0.221,0.467,0.583,0.479,0.252,0.638,0.659,0.658,0.642,0.645,0.655,0.673,0.658,0.663,0.672,0.705,0.396,0.719,0.307,0.62,0.676,0.682,0.722,0.612,0.697,0.634,0.645,0.643,0.657,0.688,0.654,0.686,0.593,0.464,0.689,0.697,0.596,0.617,0.619,0.443,0.39,0.066,0.54,0.099,0.252,0.088,0.393,0.477,0.48,0.68,0.644,1048,OrganismalFitness,P53_HUMAN,Low,Human
P84126_THETH_Chan_2017,0.508,0.58,0.603,0.617,0.564,0.578,0.364,0.526,0.644,0.623,0.569,0.552,0.588,0.319,0.551,0.559,0.605,0.596,0.571,0.618,0.419,0.507,0.478,0.558,0.521,0.584,0.589,0.571,0.653,0.522,0.553,0.469,0.606,0.359,0.474,0.499,0.536,0.515,0.526,0.547,0.56,0.568,0.581,0.465,0.032,0.543,0.51,0.337,0.452,0.512,0.125,0.543,0.527,0.487,0.549,0.551,0.519,0.526,0.553,0.561,0.562,0.622,0.61,0.603,0.484,0.638,0.682,0.692,0.701,0.693,0.698,0.517,0.689,0.461,0.563,0.619,0.545,0.608,0.532,0.577,0.615,0.639,0.567,0.629,0.625,0.567,0.299,0.222,0.637,0.465,0.471,0.492,0.531,0.602,0.654,0.646,0.659,1519,OrganismalFitness,P84126_THETH,Medium,Prokaryote
PA_I34A1_Wu_2015,0.518,0.519,0.499,0.508,0.539,0.543,0.041,0.358,0.152,0.165,0.037,0.054,0.101,0.024,0.029,0.025,0.038,0.041,0.356,0.325,0.456,0.493,0.533,0.538,0.219,0.408,0.444,0.429,0.438,0.584,0.384,0.374,0.366,0.107,0.436,0.475,0.541,0.546,0.561,0.572,0.588,0.592,0.584,0.028,0.019,0.031,0.02,0.244,0.232,0.172,0.095,0.154,0.173,0.184,0.187,0.168,0.178,0.158,0.173,0.125,0.181,0.202,0.132,0.582,0.089,0.225,0.231,0.205,0.247,0.263,0.223,0.569,0.321,0.347,0.173,0.494,0.204,0.507,0.606,0.25,0.014,0.028,0.021,0.131,0.14,0.356,0.189,-0.002,0.334,0.417,0.443,0.441,0.468,0.502,0.504,0.37,0.554,1820,OrganismalFitness,PA_I34A1,Medium,Virus
PABP_YEAST_Melamed_2013,0.663,0.617,0.541,0.55,0.654,0.648,0.474,0.569,0.637,0.663,0.688,0.662,0.678,0.476,0.566,0.648,0.716,0.684,0.695,0.541,0.638,0.665,0.666,0.692,0.638,0.698,0.7,0.676,0.666,0.674,0.703,0.635,0.671,0.261,0.638,0.648,0.64,0.689,0.692,0.688,0.683,0.687,0.684,0.605,-0.027,0.67,0.654,0.361,0.612,0.514,0.197,0.664,0.66,0.672,0.693,0.685,0.689,0.691,0.69,0.718,0.705,0.715,0.622,0.689,0.544,0.638,0.68,0.698,0.716,0.716,0.724,0.7,0.712,0.644,0.694,0.715,0.735,0.733,0.627,0.647,0.715,0.727,0.678,0.689,0.734,0.658,0.351,0.316,0.675,0.641,0.626,0.65,0.66,0.689,0.686,0.723,0.677,37708,OrganismalFitness,PABP_YEAST,Medium,Eukaryote
PAI1_HUMAN_Huttinger_2021,0.403,0.395,0.377,0.392,0.402,0.413,0.054,0.314,0.428,0.438,0.435,0.408,0.43,0.083,0.391,0.434,0.448,0.335,0.27,0.422,0.132,0.381,0.364,0.345,0.351,0.395,0.399,0.372,0.33,0.423,0.393,0.356,0.435,0.141,0.171,0.37,0.379,0.384,0.404,0.412,0.414,0.424,0.426,0.35,0.049,0.43,0.407,0.379,0.45,0.404,0.152,0.441,0.437,0.439,0.448,0.448,0.445,0.449,0.449,0.446,0.457,0.468,0.391,0.444,0.31,0.279,0.328,0.307,0.313,0.424,0.341,0.425,0.459,0.412,0.459,0.459,0.466,0.462,0.389,0.454,0.462,0.468,0.436,0.417,0.409,0.347,0.256,0.028,0.268,0.317,0.36,0.369,0.396,0.399,0.399,0.447,0.424,5345,Activity,PAI1_HUMAN,Medium,Human
PHOT_CHLRE_Chen_2023,0.211,0.44,0.731,0.706,0.352,0.335,0.654,0.552,0.711,0.721,0.647,0.757,0.783,0.768,0.823,0.714,0.749,0.714,0.758,0.652,0.685,0.678,0.596,0.699,0.533,0.616,0.596,0.656,0.602,0.587,0.572,0.49,0.596,0.303,0.565,0.511,0.602,0.597,0.564,0.606,0.416,0.445,0.422,0.623,0.395,0.599,0.621,0.2,0.502,0.669,0.41,0.603,0.543,0.553,0.551,0.555,0.57,0.568,0.574,0.583,0.569,0.737,0.775,0.702,0.173,0.309,0.379,0.368,0.422,0.438,0.355,0.517,0.445,0.753,0.75,0.62,0.74,0.62,0.411,0.652,0.757,0.696,0.715,0.664,0.669,0.578,0.653,0.298,0.522,0.531,0.47,0.523,0.552,0.665,0.722,0.697,0.726,167529,Activity,PHOT_CHLRE,High,Eukaryote
PIN1_HUMAN_Tsuboyama_2023_1I6C,0.222,0.327,0.68,0.645,0.631,0.661,0.585,0.5,0.67,0.707,0.654,0.576,0.674,0.66,0.646,0.665,0.67,0.52,0.548,0.656,0.456,0.671,0.63,0.61,0.559,0.672,0.681,0.647,0.658,0.689,0.692,0.644,0.667,0.531,0.539,0.626,0.667,0.607,0.671,0.72,0.677,0.705,0.73,0.556,-0.189,0.623,0.51,0.547,0.574,0.691,0.669,0.659,0.627,0.498,0.563,0.575,0.604,0.608,0.649,0.626,0.62,0.74,0.742,0.709,0.274,0.519,0.697,0.723,0.673,0.769,0.745,0.691,0.787,0.737,0.6,0.65,0.722,0.719,0.616,0.767,0.681,0.692,0.539,0.657,0.58,0.546,0.071,0.482,0.556,0.034,0.449,0.534,0.672,0.681,0.685,0.724,0.714,802,Stability,PIN1_HUMAN,High,Human
PITX2_HUMAN_Tsuboyama_2023_2L7M,0.579,0.52,0.548,0.555,0.549,0.553,0.506,0.47,0.538,0.561,0.467,0.446,0.436,0.557,0.652,0.675,0.626,0.586,0.507,0.542,0.513,0.454,0.477,0.45,0.547,0.493,0.465,0.428,0.468,0.536,0.403,0.386,0.543,0.45,0.558,0.508,0.481,0.596,0.548,0.538,0.573,0.537,0.538,0.468,0.412,0.282,0.333,0.453,0.295,0.693,0.63,0.572,0.579,0.572,0.59,0.602,0.609,0.593,0.594,0.598,0.598,0.47,0.593,0.558,0.592,0.677,0.638,0.638,0.707,0.533,0.562,0.558,0.553,0.629,0.646,0.606,0.678,0.623,0.524,0.56,0.437,0.429,0.425,0.416,0.373,0.558,0.324,0.149,0.378,0.443,0.574,0.602,0.606,0.55,0.509,0.736,0.572,1824,Stability,PITX2_HUMAN,High,Human
PKN1_HUMAN_Tsuboyama_2023_1URF,0.179,0.188,0.218,0.234,0.249,0.254,0.198,0.187,0.165,0.206,0.253,0.278,0.31,0.314,0.347,0.464,0.298,0.236,0.238,0.277,0.31,0.289,0.278,0.325,0.3,0.291,0.31,0.292,0.295,0.29,0.326,0.317,0.345,0.067,0.335,0.278,0.311,0.262,0.285,0.308,0.288,0.28,0.293,0.266,0.279,0.26,0.3,0.512,0.379,0.493,0.469,0.258,0.303,0.317,0.26,0.284,0.287,0.286,0.299,0.314,0.299,0.324,0.464,0.281,0.208,0.502,0.539,0.536,0.554,0.584,0.551,0.359,0.575,0.378,0.308,0.312,0.366,0.345,0.228,0.574,0.518,0.364,0.28,0.236,0.232,0.224,0.223,0.114,0.157,0.233,0.344,0.291,0.362,0.332,0.303,0.495,0.301,1301,Stability,PKN1_HUMAN,High,Human
POLG_CXB3N_Mattenberger_2021,0.423,0.39,0.377,0.411,0.46,0.473,-0.036,0.336,0.5,0.499,0.292,-0.059,0.042,-0.079,-0.056,0.177,0.395,0.404,0.426,0.356,0.339,0.39,0.381,0.377,0.138,0.388,0.383,0.369,0.393,0.495,0.386,0.319,0.42,0.007,0.049,0.274,0.355,0.342,0.385,0.413,0.387,0.43,0.458,-0.065,-0.066,0.342,-0.054,0.193,0.339,0.113,0.046,0.342,0.361,0.364,0.369,0.364,0.365,0.365,0.365,0.374,0.374,0.11,0.068,0.445,0.019,0.058,0.09,0.062,0.076,0.206,0.092,0.494,0.354,0.425,0.404,0.486,0.406,0.487,0.475,0.211,0.127,0.152,-0.0,0.43,0.383,0.36,0.279,-0.021,0.413,-0.035,-0.023,0.052,0.207,0.385,0.385,0.469,0.474,15711,OrganismalFitness,POLG_CXB3N,Medium,Virus
POLG_DEN26_Suphatrakul_2023,0.5,0.578,0.289,0.286,0.532,0.533,-0.044,0.434,0.67,0.675,0.318,-0.006,0.0,-0.044,0.007,0.077,0.153,0.275,0.366,0.409,0.453,0.473,0.449,0.456,0.47,0.501,0.493,0.488,0.461,0.622,0.603,0.522,0.514,0.035,-0.064,0.115,0.471,0.432,0.383,0.542,0.469,0.397,0.563,-0.055,-0.059,0.391,-0.005,0.36,0.51,0.101,0.116,0.241,0.229,0.244,0.26,0.227,0.261,0.24,0.246,0.223,0.254,0.161,0.032,0.662,0.025,0.173,0.169,0.177,0.215,0.398,0.193,0.645,0.488,0.61,0.263,0.499,0.314,0.528,0.605,0.295,0.062,0.066,0.235,0.603,0.585,0.446,0.377,0.02,0.243,0.357,0.438,0.442,0.401,0.458,0.402,0.636,0.663,16897,OrganismalFitness,POLG_DEN26,Low,Virus
POLG_HCVJF_Qi_2014,0.605,0.547,0.41,0.413,0.605,0.614,-0.039,0.196,0.565,0.577,0.178,0.637,0.635,0.101,0.128,0.114,0.116,0.09,0.078,0.26,0.4,0.443,0.452,0.492,0.422,0.475,0.32,0.41,0.517,0.63,0.587,0.485,0.408,0.182,0.474,0.505,0.522,0.515,0.547,0.578,0.48,0.528,0.56,0.114,0.053,0.506,0.109,-0.037,0.349,0.643,0.35,0.308,0.378,0.344,0.379,0.342,0.283,0.323,0.318,0.314,0.372,0.173,0.159,0.736,0.253,0.363,0.362,0.33,0.279,0.484,0.316,0.363,0.6,0.629,0.421,0.64,0.427,0.628,0.619,0.606,0.1,0.129,0.658,0.645,0.62,0.271,0.223,0.033,0.496,0.126,0.137,0.032,0.126,0.258,0.47,0.712,0.745,1630,OrganismalFitness,POLG_HCVJF,Medium,Virus
POLG_PESV_Tsuboyama_2023_2MXD,0.251,0.455,0.373,0.407,0.471,0.463,0.07,0.42,0.39,0.514,0.375,0.062,0.157,0.132,0.14,0.031,0.16,0.114,0.084,0.592,0.079,0.058,0.016,0.157,0.106,-0.059,0.008,-0.084,0.17,0.507,0.575,0.58,0.557,0.131,0.003,-0.033,0.053,0.382,0.383,0.384,0.453,0.463,0.452,0.006,-0.037,0.033,0.026,0.448,0.443,0.65,0.576,0.658,0.664,0.615,0.736,0.705,0.718,0.692,0.731,0.718,0.718,0.716,0.686,0.561,0.433,0.794,0.752,0.815,0.798,0.808,0.805,0.572,0.759,0.6,0.592,0.661,0.621,0.687,0.529,0.625,0.25,0.247,0.23,0.414,0.239,-0.122,-0.016,-0.17,0.269,0.195,0.243,0.077,0.011,0.205,0.215,0.651,0.58,5130,Stability,POLG_PESV,High,Virus
PPARG_HUMAN_Majithia_2016,0.353,0.539,0.629,0.655,0.612,0.632,0.187,0.339,0.557,0.571,0.623,0.696,0.695,0.028,0.126,0.456,0.594,0.736,0.768,0.717,0.675,0.692,0.25,0.288,0.592,0.722,0.692,0.719,0.299,0.712,0.583,0.509,0.685,0.384,0.709,0.683,0.587,0.673,0.7,0.637,0.698,0.706,0.68,0.266,0.03,0.585,0.45,0.594,0.607,0.631,0.302,0.58,0.588,0.593,0.575,0.599,0.583,0.602,0.598,0.585,0.603,0.657,0.499,0.579,0.493,0.248,0.201,0.27,0.219,0.462,0.268,0.725,0.538,0.746,0.643,0.688,0.658,0.695,0.699,0.514,0.571,0.633,0.687,0.683,0.699,0.703,0.605,0.076,0.419,0.374,0.338,0.568,0.733,0.718,0.535,0.627,0.336,9576,Activity,PPARG_HUMAN,Medium,Human
PPM1D_HUMAN_Miller_2022,0.55,0.523,0.531,0.536,0.609,0.61,0.035,0.378,0.46,0.517,0.578,0.599,0.618,0.281,0.386,0.47,0.602,0.628,0.618,0.387,0.45,0.526,0.537,0.43,0.516,0.577,0.567,0.557,0.419,0.601,0.594,0.546,0.612,0.234,0.428,0.528,0.537,0.582,0.593,0.591,0.615,0.614,0.616,0.361,-0.05,0.575,0.515,0.503,0.579,0.563,0.236,0.574,0.575,0.57,0.586,0.593,0.58,0.584,0.585,0.59,0.595,0.633,0.509,0.62,0.325,0.218,0.271,0.299,0.34,0.508,0.319,0.611,0.575,0.604,0.614,0.641,0.614,0.641,0.586,0.491,0.613,0.618,0.599,0.573,0.584,0.561,0.465,0.23,0.503,0.338,0.45,0.493,0.572,0.595,0.546,0.641,0.577,7889,OrganismalFitness,PPM1D_HUMAN,Low,Human
PR40A_HUMAN_Tsuboyama_2023_1UZC,0.562,0.655,0.745,0.736,0.772,0.774,0.518,0.493,0.774,0.783,0.727,0.592,0.681,0.54,0.535,0.821,0.805,0.74,0.727,0.715,0.552,0.694,0.7,0.725,0.634,0.716,0.733,0.723,0.744,0.795,0.777,0.756,0.795,0.637,0.593,0.556,0.611,0.735,0.746,0.738,0.764,0.784,0.775,0.438,0.281,0.326,0.431,0.639,0.423,0.794,0.783,0.792,0.809,0.804,0.812,0.828,0.823,0.819,0.816,0.816,0.821,0.801,0.835,0.785,0.463,0.764,0.822,0.776,0.852,0.861,0.823,0.782,0.858,0.813,0.835,0.824,0.863,0.84,0.763,0.847,0.805,0.774,0.738,0.682,0.703,0.694,0.436,0.168,0.665,0.339,0.513,0.598,0.664,0.651,0.77,0.846,0.857,2033,Stability,PR40A_HUMAN,Medium,Human
PRKN_HUMAN_Clausen_2023,0.605,0.619,0.6,0.586,0.622,0.614,0.182,0.459,0.525,0.54,0.582,0.608,0.638,0.233,0.292,0.363,0.501,0.658,0.663,0.447,0.281,0.557,0.609,0.576,0.447,0.632,0.623,0.623,0.52,0.622,0.568,0.526,0.637,0.266,0.241,0.55,0.593,0.569,0.621,0.64,0.611,0.638,0.654,0.309,0.093,0.591,0.352,0.649,0.618,0.696,0.298,0.542,0.555,0.561,0.583,0.567,0.571,0.579,0.573,0.561,0.583,0.672,0.519,0.641,0.386,0.455,0.52,0.492,0.556,0.633,0.545,0.65,0.68,0.672,0.617,0.672,0.642,0.674,0.625,0.611,0.425,0.587,0.477,0.587,0.585,0.581,0.379,-0.044,0.511,0.183,0.238,0.342,0.43,0.574,0.599,0.657,0.582,8756,Expression,PRKN_HUMAN,Low,Human
PSAE_PICP2_Tsuboyama_2023_1PSE,0.572,0.576,0.566,0.566,0.576,0.572,0.3,0.442,0.491,0.497,0.692,0.601,0.615,0.498,0.57,0.678,0.708,0.627,0.583,0.477,0.304,0.242,0.467,0.391,0.462,0.492,-0.202,0.471,0.529,0.553,0.558,0.505,0.628,0.098,0.328,0.409,0.43,0.546,0.543,0.498,0.586,0.585,0.541,0.422,0.237,0.635,0.482,0.586,0.626,0.699,0.643,0.7,0.684,0.687,0.685,0.686,0.692,0.681,0.687,0.689,0.699,0.682,0.674,0.578,0.586,0.598,0.621,0.626,0.692,0.737,0.717,0.588,0.731,0.634,0.71,0.671,0.73,0.677,0.546,0.677,0.64,0.596,0.649,0.611,0.614,0.514,0.371,0.438,0.546,0.441,0.537,0.344,0.482,0.495,0.542,0.647,0.625,1579,Stability,PSAE_PICP2,Medium,Prokaryote
PTEN_HUMAN_Matreyek_2021,0.372,0.393,0.368,0.39,0.397,0.408,0.153,0.358,0.426,0.471,0.449,0.409,0.454,0.165,0.274,0.462,0.465,0.265,0.29,0.477,0.191,0.46,0.408,0.391,0.27,0.338,0.323,0.377,0.294,0.479,0.39,0.388,0.469,0.127,0.275,0.427,0.343,0.383,0.457,0.412,0.419,0.463,0.447,0.242,0.027,0.442,0.347,0.482,0.473,0.482,0.229,0.446,0.428,0.461,0.441,0.44,0.451,0.456,0.455,0.447,0.46,0.499,0.454,0.478,0.336,0.414,0.475,0.504,0.514,0.497,0.475,0.505,0.516,0.46,0.475,0.472,0.475,0.467,0.449,0.473,0.481,0.456,0.449,0.353,0.369,0.391,0.285,0.067,0.295,0.19,0.202,0.232,0.3,0.429,0.326,0.496,0.432,5083,Expression,PTEN_HUMAN,Medium,Human
PTEN_HUMAN_Mighell_2018,0.48,0.504,0.511,0.516,0.536,0.54,0.177,0.347,0.504,0.511,0.475,0.469,0.499,0.206,0.407,0.546,0.519,0.308,0.291,0.514,0.335,0.413,0.328,0.279,0.41,0.291,0.278,0.317,0.228,0.525,0.485,0.475,0.55,0.058,0.374,0.404,0.299,0.499,0.474,0.418,0.532,0.527,0.531,0.371,-0.009,0.51,0.484,0.421,0.416,0.48,0.202,0.488,0.459,0.488,0.495,0.511,0.505,0.495,0.495,0.509,0.51,0.539,0.51,0.556,0.267,0.395,0.417,0.443,0.462,0.513,0.447,0.524,0.524,0.519,0.508,0.555,0.531,0.561,0.508,0.539,0.555,0.544,0.517,0.402,0.404,0.322,0.271,0.065,0.285,0.254,0.346,0.368,0.399,0.388,0.328,0.518,0.504,7260,Activity,PTEN_HUMAN,Medium,Human
Q2N0S5_9HIV1_Haddox_2018,0.493,0.379,0.352,0.393,0.495,0.502,0.003,0.437,0.51,0.515,0.47,0.509,0.537,-0.005,-0.003,-0.002,0.044,0.093,0.168,0.403,0.518,0.403,0.39,0.337,0.517,0.401,0.394,0.436,0.354,0.507,0.478,0.483,0.348,0.291,0.494,0.419,0.406,0.52,0.502,0.501,0.526,0.515,0.513,0.413,-0.016,0.502,0.456,0.396,0.463,0.263,0.145,0.226,0.266,0.307,0.301,0.25,0.257,0.26,0.245,0.223,0.28,0.232,0.116,0.489,0.06,0.364,0.411,0.418,0.422,0.495,0.456,0.534,0.591,0.555,0.352,0.54,0.403,0.566,0.521,0.347,0.512,0.496,0.497,0.403,0.33,0.369,0.345,0.055,0.152,0.439,0.477,0.499,0.501,0.515,0.501,0.623,0.515,12729,OrganismalFitness,Q2N0S5_9HIV1,Medium,Virus
Q53Z42_HUMAN_McShan_2019_binding-TAPBPR,0.356,0.341,0.348,0.353,0.358,0.355,0.081,0.245,0.314,0.324,0.235,0.301,0.325,0.192,0.186,0.364,0.33,0.287,0.347,0.329,0.249,0.267,0.257,0.215,0.292,0.297,0.268,0.306,0.299,0.303,0.371,0.341,0.276,0.098,0.238,0.268,0.182,0.311,0.334,0.294,0.352,0.365,0.348,0.402,0.202,0.321,0.328,0.311,0.341,0.338,0.192,0.291,0.302,0.333,0.334,0.321,0.321,0.316,0.312,0.312,0.325,0.33,0.465,0.35,0.315,0.373,0.445,0.439,0.422,0.435,0.457,0.305,0.454,0.337,0.318,0.367,0.327,0.372,0.351,0.337,0.303,0.332,0.312,0.27,0.268,0.304,0.254,0.105,0.183,0.153,0.199,0.24,0.279,0.321,0.256,0.405,0.372,3344,Binding,Q53Z42_HUMAN,Medium,Human
Q53Z42_HUMAN_McShan_2019_expression,0.524,0.485,0.526,0.538,0.55,0.548,-0.062,0.415,0.541,0.556,0.413,0.467,0.507,0.088,0.106,0.489,0.554,0.55,0.558,0.546,0.415,0.47,0.459,0.448,0.476,0.514,0.492,0.511,0.534,0.533,0.553,0.505,0.568,0.183,0.417,0.44,0.405,0.52,0.538,0.533,0.555,0.564,0.563,0.308,0.093,0.526,0.483,0.454,0.49,0.458,0.207,0.533,0.546,0.555,0.551,0.565,0.556,0.557,0.56,0.564,0.57,0.513,0.622,0.588,0.428,0.44,0.49,0.495,0.503,0.597,0.52,0.578,0.636,0.608,0.556,0.594,0.576,0.603,0.554,0.578,0.521,0.533,0.46,0.48,0.51,0.445,0.414,0.142,0.436,0.147,0.321,0.391,0.425,0.509,0.471,0.633,0.556,3344,Expression,Q53Z42_HUMAN,Medium,Human
Q59976_STRSQ_Romero_2015,0.475,0.593,0.634,0.643,0.654,0.662,0.363,0.535,0.672,0.679,0.588,0.519,0.543,0.144,0.448,0.516,0.572,0.56,0.57,0.649,0.598,0.651,0.652,0.663,0.622,0.662,0.677,0.673,0.68,0.684,0.633,0.575,0.631,0.304,0.606,0.652,0.634,0.616,0.653,0.657,0.666,0.672,0.675,0.49,0.008,0.587,0.524,0.408,0.533,0.533,0.155,0.56,0.537,0.533,0.556,0.557,0.542,0.562,0.545,0.553,0.563,0.634,0.54,0.593,0.468,0.356,0.38,0.382,0.432,0.569,0.426,0.673,0.602,0.639,0.58,0.661,0.585,0.666,0.627,0.579,0.652,0.657,0.654,0.67,0.672,0.555,0.408,0.343,0.641,0.589,0.625,0.623,0.65,0.658,0.678,0.692,0.611,2999,Activity,Q59976_STRSQ,Medium,Prokaryote
Q6WV12_9MAXI_Somermeyer_2022,0.327,0.393,0.26,0.264,0.333,0.334,-0.031,0.115,0.413,0.407,0.242,0.036,0.022,0.014,0.046,0.011,0.01,0.01,-0.022,0.294,0.013,0.045,0.003,0.102,0.004,-0.002,0.03,-0.005,-0.013,0.426,0.344,0.354,0.359,0.043,0.031,0.022,0.014,0.248,0.246,0.245,0.33,0.327,0.324,0.014,-0.015,-0.004,0.019,0.161,0.156,0.299,0.169,0.228,0.248,0.237,0.287,0.267,0.272,0.261,0.263,0.264,0.261,0.072,0.031,0.456,0.052,0.386,0.457,0.444,0.41,0.265,0.466,0.467,0.314,0.514,0.104,0.273,0.172,0.311,0.39,0.149,0.002,-0.007,0.042,-0.012,-0.003,0.001,-0.06,0.048,0.083,-0.014,-0.015,-0.005,0.016,-0.024,0.002,0.428,0.477,31401,Activity,Q6WV12_9MAXI,Low,Eukaryote
Q837P4_ENTFA_Meier_2023,0.451,0.465,0.489,0.507,0.503,0.517,0.454,0.404,0.479,0.495,0.563,0.545,0.566,0.42,0.475,0.492,0.515,0.545,0.523,-0.019,0.521,0.445,0.441,0.462,0.552,0.535,0.541,0.449,0.521,0.524,0.527,0.477,0.487,0.19,0.491,0.516,0.454,0.491,0.538,0.512,0.54,0.549,0.544,0.458,0.37,0.545,0.49,0.231,0.454,0.373,0.114,0.511,0.488,0.499,0.511,0.522,0.529,0.536,0.491,0.524,0.531,0.589,0.483,0.433,0.409,0.42,0.514,0.502,0.403,0.631,0.462,0.507,0.628,0.56,0.523,0.553,0.537,0.557,0.465,0.509,0.511,0.522,0.519,0.529,0.507,0.452,0.21,0.335,0.426,0.541,0.517,0.496,0.471,0.475,0.35,0.533,0.529,697,Activity,Q837P4_ENTFA,Medium,Prokaryote
Q837P5_ENTFA_Meier_2023,0.196,0.416,0.421,0.459,0.39,0.395,0.222,0.263,0.282,0.294,0.326,0.353,0.342,0.129,0.24,0.334,0.374,0.436,0.392,0.321,0.356,0.399,0.435,0.41,0.319,0.408,0.428,0.511,0.455,0.336,0.378,0.352,0.329,0.186,0.399,0.427,0.51,0.342,0.391,0.477,0.417,0.428,0.457,0.274,0.186,0.356,0.271,0.353,0.296,0.391,0.098,0.326,0.344,0.359,0.313,0.383,0.348,0.318,0.353,0.32,0.355,0.341,0.319,0.315,0.174,0.486,0.577,0.504,0.446,0.573,0.427,0.367,0.531,0.257,0.404,0.425,0.374,0.413,0.359,0.414,0.334,0.364,0.377,0.479,0.451,0.337,0.04,0.02,0.373,0.421,0.428,0.4,0.421,0.455,0.385,0.523,0.344,747,Activity,Q837P5_ENTFA,Medium,Prokaryote
Q8WTC7_9CNID_Somermeyer_2022,0.286,0.368,0.217,0.215,0.31,0.305,0.025,0.303,0.316,0.322,0.223,-0.009,-0.018,-0.027,-0.035,-0.023,-0.025,-0.007,0.034,0.23,0.013,0.037,0.057,0.013,-0.005,-0.001,0.037,0.252,0.267,0.373,0.297,0.307,0.299,-0.018,-0.026,0.009,0.303,0.231,0.237,0.318,0.304,0.309,0.345,-0.013,-0.008,-0.024,-0.027,0.097,0.143,0.292,0.189,0.242,0.234,0.246,0.26,0.24,0.254,0.249,0.243,0.238,0.247,0.137,-0.001,0.353,0.042,0.355,0.388,0.393,0.42,0.279,0.475,0.417,0.315,0.485,0.162,0.277,0.201,0.302,0.353,0.211,-0.012,-0.037,-0.016,-0.026,-0.018,0.004,-0.047,0.011,0.299,-0.018,0.032,-0.001,0.03,0.215,0.247,0.32,0.337,33510,Activity,Q8WTC7_9CNID,Low,Eukaryote
R1AB_SARS2_Flynn_2022,0.577,0.561,0.212,0.227,0.6,0.605,-0.049,0.292,-0.037,-0.037,0.103,-0.03,-0.04,-0.009,-0.026,0.079,0.105,0.498,0.577,0.266,0.214,0.259,0.274,0.289,0.242,0.236,0.203,0.21,0.224,0.558,0.507,0.408,0.488,-0.056,0.157,0.22,0.216,0.35,0.399,0.401,0.546,0.567,0.565,-0.031,-0.051,0.073,-0.038,0.453,0.415,0.496,0.232,0.251,0.228,0.265,0.298,0.275,0.274,0.273,0.268,0.237,0.277,0.241,0.137,0.667,0.034,0.259,0.319,0.325,0.383,0.43,0.367,0.641,0.442,0.654,0.291,0.546,0.327,0.565,0.588,0.401,-0.043,0.012,0.145,0.349,0.343,0.026,-0.112,-0.01,0.23,0.031,0.072,0.18,0.047,0.121,0.147,0.629,0.63,5725,OrganismalFitness,R1AB_SARS2,Medium,Virus
RAD_ANTMA_Tsuboyama_2023_2CJJ,0.28,0.183,0.286,0.299,0.324,0.356,0.508,0.373,0.654,0.624,0.507,0.403,0.45,0.458,0.687,0.704,0.493,0.467,0.542,0.412,0.541,0.575,0.536,0.454,0.552,0.419,0.546,0.444,0.417,0.598,0.422,0.365,0.405,0.258,0.477,0.601,0.439,0.497,0.588,0.467,0.436,0.486,0.41,0.573,0.222,0.147,0.37,0.46,0.233,0.656,0.548,0.544,0.578,0.577,0.577,0.606,0.581,0.571,0.575,0.573,0.585,0.373,0.582,0.346,0.294,0.622,0.708,0.685,0.618,0.658,0.723,0.478,0.696,0.479,0.535,0.475,0.54,0.472,0.404,0.555,0.383,0.426,0.474,0.392,0.418,0.331,0.386,0.089,0.314,0.374,0.381,0.532,0.524,0.493,0.416,0.57,0.403,912,Stability,RAD_ANTMA,High,Eukaryote
RAF1_HUMAN_Zinkus-Boltz_2019,0.405,0.425,0.382,0.389,0.408,0.408,0.045,0.339,0.445,0.439,0.471,0.423,0.482,0.034,0.242,0.442,0.473,0.433,0.399,0.311,0.285,0.378,0.378,0.339,0.377,0.395,0.378,0.355,0.359,0.439,0.473,0.421,0.468,0.12,0.287,0.339,0.363,0.372,0.38,0.396,0.403,0.43,0.441,0.221,0.039,0.48,0.387,0.271,0.383,0.264,0.234,0.456,0.43,0.437,0.483,0.451,0.475,0.439,0.453,0.46,0.472,0.432,0.16,0.338,0.251,0.285,0.393,0.274,0.35,0.361,0.352,0.455,0.403,0.399,0.457,0.467,0.484,0.478,0.436,0.27,0.473,0.454,0.459,0.417,0.369,0.355,0.288,-0.119,0.39,0.057,0.058,0.15,0.336,0.385,0.359,0.416,0.463,297,OrganismalFitness,RAF1_HUMAN,Low,Human
RASH_HUMAN_Bandaru_2017,0.447,0.436,0.444,0.476,0.466,0.48,0.313,0.353,0.426,0.446,0.318,0.36,0.405,0.457,0.514,0.487,0.498,0.44,0.313,0.514,0.437,0.414,0.42,0.396,0.433,0.403,0.401,0.374,0.305,0.434,0.338,0.319,0.503,0.18,0.399,0.439,0.377,0.454,0.478,0.45,0.472,0.485,0.487,0.478,0.326,0.322,0.453,0.386,0.252,0.458,0.255,0.431,0.423,0.443,0.428,0.456,0.43,0.452,0.43,0.439,0.455,0.373,0.474,0.501,0.413,0.563,0.568,0.562,0.596,0.619,0.575,0.461,0.589,0.448,0.492,0.513,0.49,0.512,0.437,0.463,0.422,0.366,0.328,0.284,0.349,0.299,0.324,0.412,0.241,0.429,0.411,0.438,0.439,0.424,0.382,0.519,0.482,3134,Activity,RASH_HUMAN,High,Human
RASK_HUMAN_Weng_2022_abundance,0.299,0.244,0.356,0.346,0.332,0.353,0.211,0.244,0.244,0.271,0.276,0.21,0.245,0.336,0.367,0.335,0.271,0.231,0.21,0.331,0.266,0.333,0.372,0.384,0.279,0.347,0.402,0.345,0.47,0.357,0.21,0.167,0.308,0.208,0.198,0.325,0.398,0.275,0.368,0.436,0.334,0.37,0.388,0.237,0.335,0.058,0.243,0.334,0.327,0.377,0.326,0.264,0.245,0.294,0.279,0.31,0.281,0.298,0.28,0.26,0.287,0.339,0.331,0.302,0.32,0.455,0.41,0.386,0.399,0.372,0.377,0.328,0.362,0.272,0.3,0.344,0.273,0.326,0.324,0.31,0.17,0.191,0.241,0.283,0.235,0.323,0.282,0.261,0.268,0.189,0.203,0.264,0.235,0.35,0.352,0.444,0.281,26012,Expression,RASK_HUMAN,High,Human
RASK_HUMAN_Weng_2022_binding-DARPin_K55,0.419,0.47,0.602,0.617,0.598,0.598,0.268,0.35,0.641,0.639,0.585,0.524,0.566,0.573,0.605,0.621,0.652,0.563,0.446,0.677,0.568,0.511,0.549,0.458,0.537,0.534,0.479,0.396,0.358,0.569,0.529,0.49,0.634,0.289,0.515,0.589,0.499,0.555,0.601,0.543,0.605,0.616,0.597,0.56,0.298,0.464,0.597,0.239,0.269,0.585,0.281,0.545,0.549,0.542,0.552,0.556,0.554,0.544,0.543,0.51,0.56,0.601,0.573,0.685,0.535,0.589,0.705,0.651,0.696,0.689,0.71,0.57,0.671,0.58,0.601,0.627,0.637,0.646,0.595,0.584,0.645,0.602,0.594,0.564,0.608,0.449,0.457,0.402,0.422,0.573,0.536,0.593,0.556,0.563,0.48,0.558,0.65,24873,Binding,RASK_HUMAN,High,Human
RBP1_HUMAN_Tsuboyama_2023_2KWH,0.19,0.108,0.302,0.307,0.305,0.303,0.271,0.277,0.218,0.233,0.43,0.409,0.404,0.321,0.394,0.491,0.552,0.328,0.335,0.259,0.366,0.108,0.267,0.263,0.297,0.078,0.16,0.293,0.202,0.365,0.373,0.318,0.362,0.239,0.291,0.364,0.384,0.318,0.34,0.339,0.317,0.334,0.318,0.319,0.255,0.415,0.406,0.487,0.545,0.578,0.459,0.494,0.479,0.491,0.485,0.492,0.486,0.476,0.493,0.48,0.493,0.539,0.526,0.275,0.321,0.609,0.605,0.622,0.653,0.533,0.582,0.398,0.519,0.433,0.556,0.474,0.592,0.494,0.297,0.585,0.482,0.526,0.288,0.512,0.34,0.164,0.062,0.009,0.309,0.315,0.317,0.357,0.341,0.28,0.288,0.461,0.254,1332,Stability,RBP1_HUMAN,High,Human
RCD1_ARATH_Tsuboyama_2023_5OAO,0.304,0.284,0.362,0.37,0.367,0.355,0.303,0.255,0.412,0.421,0.486,0.342,0.393,0.368,0.392,0.498,0.505,0.482,0.478,0.391,0.267,0.243,0.33,0.395,0.32,0.481,0.454,0.412,0.465,0.398,0.478,0.406,0.552,0.046,0.293,0.308,0.324,0.36,0.361,0.352,0.403,0.402,0.386,0.304,0.285,0.371,0.327,0.442,0.432,0.56,0.532,0.541,0.555,0.559,0.559,0.545,0.555,0.551,0.549,0.556,0.56,0.531,0.501,0.456,0.456,0.633,0.625,0.602,0.609,0.593,0.631,0.434,0.614,0.459,0.546,0.472,0.557,0.478,0.404,0.571,0.515,0.529,0.422,0.487,0.45,0.301,-0.018,-0.073,0.408,0.302,0.243,0.321,0.356,0.42,0.472,0.46,0.455,1261,Stability,RCD1_ARATH,Medium,Eukaryote
RCRO_LAMBD_Tsuboyama_2023_1ORC,0.293,0.518,0.584,0.577,0.557,0.588,0.167,0.263,0.552,0.556,0.558,0.38,0.492,0.226,0.422,0.451,0.596,0.573,0.639,0.573,0.129,0.17,0.225,0.175,-0.041,0.132,-0.003,0.087,0.577,0.59,0.569,0.537,0.559,0.096,0.178,0.127,0.567,0.44,0.45,0.58,0.568,0.598,0.621,0.028,0.139,0.471,0.187,0.635,0.646,0.782,0.69,0.592,0.58,0.56,0.585,0.574,0.583,0.568,0.569,0.6,0.584,0.646,0.541,0.653,0.251,0.767,0.66,0.615,0.729,0.79,0.716,0.668,0.79,0.644,0.693,0.658,0.732,0.681,0.484,0.684,0.568,0.615,0.395,0.632,0.721,0.27,-0.132,0.243,0.596,0.169,-0.012,0.173,0.519,0.499,0.554,0.74,0.689,2278,Stability,RCRO_LAMBD,High,Virus
RD23A_HUMAN_Tsuboyama_2023_1IFY,0.33,0.333,0.466,0.466,0.479,0.479,0.196,0.434,0.512,0.517,0.457,0.55,0.592,0.254,0.675,0.533,0.513,0.464,0.39,0.462,0.422,0.422,0.395,0.453,0.545,0.513,0.51,0.477,0.494,0.51,0.414,0.399,0.503,0.429,0.288,0.531,0.475,0.484,0.568,0.54,0.482,0.537,0.536,0.512,0.074,0.556,0.548,0.502,0.548,0.582,0.505,0.47,0.454,0.467,0.449,0.478,0.475,0.475,0.474,0.478,0.481,0.482,0.631,0.479,0.515,0.581,0.635,0.639,0.639,0.628,0.595,0.561,0.648,0.655,0.521,0.525,0.525,0.528,0.457,0.577,0.507,0.454,0.494,0.491,0.479,0.431,0.469,-0.059,0.391,0.133,0.117,0.383,0.495,0.498,0.55,0.65,0.525,1019,Stability,RD23A_HUMAN,High,Human
RDRP_I33A0_Li_2023,0.313,0.367,0.376,0.387,0.482,0.484,0.029,0.355,0.52,0.525,0.166,0.045,0.057,0.033,0.041,0.128,0.322,0.389,0.491,0.427,0.385,0.436,0.454,0.475,0.125,0.358,0.342,0.345,0.413,0.52,0.45,0.395,0.432,0.075,0.377,0.423,0.459,0.425,0.452,0.474,0.494,0.508,0.526,0.03,0.02,0.171,0.033,0.215,0.23,0.188,0.055,0.3,0.271,0.279,0.282,0.303,0.296,0.283,0.304,0.31,0.307,0.149,0.11,0.573,0.071,0.168,0.168,0.171,0.192,0.294,0.182,0.52,0.321,0.334,0.319,0.477,0.322,0.486,0.546,0.224,0.074,0.081,0.092,0.419,0.363,0.265,0.166,-0.004,0.309,0.34,0.368,0.374,0.387,0.426,0.448,0.449,0.567,12003,OrganismalFitness,RDRP_I33A0,Medium,Virus
REV_HV1H2_Fernandes_2016,0.206,0.159,0.221,0.227,0.216,0.216,0.038,0.316,0.222,0.232,0.128,0.245,0.267,0.046,0.046,0.173,0.24,0.281,0.274,0.17,0.216,0.259,0.238,0.24,0.29,0.294,0.16,0.253,0.255,0.282,0.35,0.353,0.368,0.06,0.231,0.273,0.24,0.245,0.269,0.236,0.246,0.261,0.235,0.053,0.06,0.208,0.071,0.258,0.234,0.304,0.224,0.193,0.221,0.276,0.246,0.267,0.255,0.281,0.241,0.31,0.279,0.274,0.229,0.262,0.289,0.405,0.446,0.436,0.447,0.33,0.454,0.297,0.33,0.33,0.278,0.299,0.326,0.327,0.243,0.28,0.142,0.391,0.218,0.246,0.22,0.003,0.125,-0.139,0.201,0.05,0.218,0.383,0.382,0.223,0.243,0.312,0.238,2147,OrganismalFitness,REV_HV1H2,High,Virus
RFAH_ECOLI_Tsuboyama_2023_2LCL,0.064,0.21,0.212,0.233,0.23,0.227,-0.015,0.238,0.232,0.258,0.248,0.175,0.2,-0.032,0.078,0.055,0.299,0.261,0.246,0.249,-0.067,0.059,0.121,0.115,-0.043,0.13,0.151,0.114,0.158,0.214,0.268,0.213,0.277,-0.009,0.009,0.102,0.133,0.107,0.144,0.156,0.22,0.216,0.208,0.115,-0.075,0.193,0.107,0.304,0.248,0.384,0.328,0.331,0.31,0.291,0.333,0.314,0.3,0.314,0.309,0.327,0.319,0.318,0.22,0.297,0.009,0.156,0.283,0.272,0.256,0.474,0.271,0.285,0.446,0.316,0.304,0.28,0.349,0.306,0.084,0.408,0.294,0.31,0.17,0.315,0.287,0.018,-0.023,-0.044,0.31,-0.016,0.119,0.129,0.14,0.139,0.181,0.421,0.317,1326,Stability,RFAH_ECOLI,High,Prokaryote
RL20_AQUAE_Tsuboyama_2023_1GYZ,0.341,0.588,0.607,0.601,0.603,0.61,0.224,0.577,0.405,0.352,0.675,0.67,0.657,0.235,0.421,0.487,0.699,0.68,0.676,0.613,0.151,0.493,0.47,0.475,0.473,0.481,0.534,0.545,0.622,0.636,0.563,0.544,0.662,0.078,0.481,0.522,0.506,0.54,0.579,0.574,0.588,0.624,0.625,0.041,-0.048,0.467,0.283,0.684,0.64,0.816,0.769,0.716,0.715,0.72,0.726,0.713,0.718,0.723,0.724,0.732,0.728,0.738,0.71,0.623,0.629,0.766,0.753,0.791,0.749,0.819,0.796,0.702,0.803,0.714,0.593,0.632,0.685,0.669,0.585,0.762,0.668,0.678,0.6,0.687,0.674,0.27,-0.017,-0.173,0.668,0.463,0.424,0.53,0.527,0.555,0.628,0.753,0.602,1461,Stability,RL20_AQUAE,High,Prokaryote
RL40A_YEAST_Mavor_2016,0.283,0.37,0.372,0.417,0.38,0.399,0.122,0.372,0.441,0.448,0.192,0.285,0.315,0.104,0.397,0.482,0.518,0.446,0.527,0.43,0.382,0.512,0.48,0.422,0.493,0.433,0.433,0.43,0.4,0.319,0.406,0.408,0.498,0.044,0.387,0.451,0.368,0.407,0.456,0.398,0.439,0.469,0.411,0.286,0.071,0.282,0.294,0.068,0.091,0.177,-0.026,0.487,0.457,0.481,0.47,0.499,0.476,0.474,0.498,0.498,0.503,0.338,0.345,0.408,0.243,0.589,0.62,0.635,0.638,0.628,0.59,0.335,0.616,0.182,0.484,0.479,0.477,0.479,0.379,0.228,0.398,0.389,0.373,0.364,0.293,0.326,0.054,0.244,0.262,0.313,0.443,0.51,0.499,0.463,0.463,0.546,0.468,1253,OrganismalFitness,RL40A_YEAST,Medium,Eukaryote
RL40A_YEAST_Roscoe_2013,0.313,0.402,0.418,0.47,0.43,0.454,0.086,0.367,0.528,0.528,0.218,0.307,0.367,0.122,0.423,0.534,0.599,0.479,0.556,0.488,0.424,0.553,0.549,0.467,0.537,0.49,0.503,0.487,0.46,0.391,0.523,0.538,0.573,0.139,0.437,0.522,0.427,0.459,0.526,0.449,0.494,0.533,0.467,0.357,0.076,0.317,0.319,0.106,0.116,0.253,0.026,0.569,0.529,0.554,0.532,0.566,0.558,0.542,0.582,0.58,0.583,0.381,0.391,0.464,0.301,0.627,0.703,0.702,0.724,0.729,0.676,0.403,0.71,0.227,0.575,0.56,0.571,0.56,0.42,0.259,0.45,0.424,0.398,0.415,0.342,0.379,-0.029,0.238,0.304,0.36,0.514,0.548,0.582,0.529,0.529,0.581,0.498,1195,OrganismalFitness,RL40A_YEAST,Medium,Eukaryote
RL40A_YEAST_Roscoe_2014,0.371,0.285,0.351,0.387,0.331,0.368,0.161,0.381,0.419,0.442,0.163,0.24,0.267,0.227,0.521,0.529,0.53,0.427,0.438,0.394,0.37,0.466,0.433,0.405,0.439,0.38,0.373,0.336,0.325,0.359,0.35,0.361,0.498,0.236,0.39,0.431,0.351,0.425,0.455,0.408,0.42,0.428,0.383,0.292,0.154,0.268,0.295,0.317,0.247,0.38,0.207,0.527,0.511,0.488,0.544,0.547,0.543,0.491,0.517,0.516,0.544,0.302,0.401,0.424,0.262,0.621,0.65,0.658,0.666,0.708,0.651,0.379,0.705,0.29,0.543,0.489,0.538,0.489,0.418,0.349,0.332,0.288,0.275,0.308,0.234,0.238,-0.023,0.206,0.204,0.34,0.405,0.43,0.437,0.387,0.362,0.64,0.43,1380,Activity,RL40A_YEAST,Medium,Eukaryote
RNC_ECOLI_Weeks_2023,0.544,0.592,0.57,0.584,0.594,0.595,0.058,0.423,0.591,0.591,0.59,0.579,0.593,0.064,0.557,0.588,0.596,0.595,0.592,0.586,0.554,0.57,0.509,0.499,0.557,0.584,0.583,0.586,0.571,0.594,0.578,0.539,0.608,0.187,0.538,0.54,0.431,0.581,0.587,0.545,0.617,0.616,0.606,0.529,0.06,0.588,0.567,0.299,0.524,0.281,0.177,0.541,0.53,0.52,0.553,0.544,0.533,0.548,0.543,0.544,0.554,0.608,0.533,0.608,0.434,0.276,0.306,0.302,0.329,0.552,0.329,0.622,0.579,0.54,0.558,0.598,0.555,0.594,0.582,0.565,0.612,0.627,0.583,0.594,0.576,0.53,0.376,0.098,0.519,0.579,0.583,0.598,0.505,0.442,0.437,0.622,0.623,4277,Activity,RNC_ECOLI,Medium,Prokaryote
RPC1_BP434_Tsuboyama_2023_1R69,0.627,0.681,0.655,0.673,0.606,0.644,0.67,0.593,0.617,0.659,0.711,0.744,0.75,0.722,0.741,0.752,0.708,0.687,0.63,0.697,0.699,0.75,0.735,0.682,0.742,0.731,0.718,0.723,0.66,0.743,0.666,0.609,0.705,0.621,0.633,0.738,0.716,0.72,0.747,0.737,0.699,0.693,0.69,0.749,0.674,0.735,0.728,0.696,0.64,0.793,0.723,0.702,0.672,0.687,0.7,0.699,0.69,0.711,0.702,0.711,0.708,0.756,0.764,0.736,0.679,0.727,0.722,0.74,0.792,0.754,0.775,0.761,0.765,0.76,0.728,0.717,0.738,0.721,0.709,0.784,0.749,0.726,0.729,0.744,0.693,0.628,0.583,0.051,0.66,0.727,0.739,0.746,0.742,0.678,0.719,0.8,0.75,1459,Stability,RPC1_BP434,High,Virus
RPC1_LAMBD_Li_2019_high-expression,0.288,0.398,0.484,0.493,0.45,0.447,0.24,0.361,0.457,0.47,0.442,0.461,0.514,0.29,0.289,0.401,0.549,0.52,0.509,0.434,0.176,0.29,0.351,0.386,0.223,0.349,0.323,0.305,0.467,0.383,0.535,0.472,0.466,0.11,0.149,0.338,0.457,0.278,0.362,0.464,0.416,0.449,0.491,0.297,0.314,0.418,0.328,0.25,0.407,0.376,0.176,0.544,0.52,0.514,0.532,0.547,0.555,0.533,0.531,0.538,0.553,0.523,0.398,0.526,0.274,0.542,0.535,0.523,0.564,0.519,0.543,0.437,0.507,0.476,0.52,0.514,0.484,0.495,0.365,0.429,0.555,0.564,0.401,0.49,0.491,0.344,-0.023,-0.007,0.489,0.199,0.306,0.367,0.387,0.421,0.444,0.483,0.52,351,Activity,RPC1_LAMBD,High,Virus
RPC1_LAMBD_Li_2019_low-expression,0.246,0.412,0.475,0.498,0.462,0.455,0.165,0.466,0.45,0.468,0.488,0.466,0.481,0.253,0.263,0.363,0.523,0.579,0.591,0.408,0.195,0.338,0.38,0.415,0.182,0.366,0.321,0.299,0.562,0.447,0.635,0.611,0.521,0.119,0.135,0.322,0.463,0.235,0.323,0.454,0.42,0.447,0.498,0.269,0.271,0.357,0.28,0.262,0.375,0.393,0.266,0.52,0.488,0.51,0.519,0.503,0.53,0.522,0.511,0.494,0.528,0.518,0.344,0.499,0.296,0.568,0.641,0.585,0.63,0.623,0.63,0.493,0.594,0.487,0.505,0.511,0.468,0.494,0.422,0.442,0.554,0.57,0.316,0.44,0.426,0.313,0.054,-0.059,0.579,0.262,0.252,0.322,0.333,0.452,0.506,0.511,0.529,351,Activity,RPC1_LAMBD,High,Virus
RS15_GEOSE_Tsuboyama_2023_1A32,0.393,0.31,0.336,0.328,0.321,0.326,0.178,0.188,0.387,0.389,0.468,0.394,0.39,0.289,0.326,0.51,0.409,0.372,0.33,0.291,0.199,0.33,0.317,0.323,0.297,0.34,0.416,0.362,0.367,0.375,0.413,0.396,0.418,0.117,0.423,0.325,0.306,0.453,0.377,0.365,0.395,0.348,0.32,0.333,0.262,0.443,0.381,0.582,0.44,0.607,0.55,0.396,0.403,0.403,0.399,0.407,0.377,0.415,0.42,0.395,0.413,0.433,0.646,0.38,0.274,0.612,0.563,0.632,0.687,0.633,0.624,0.449,0.619,0.55,0.424,0.392,0.46,0.406,0.307,0.517,0.368,0.354,0.329,0.377,0.392,0.204,0.17,-0.053,0.306,0.325,0.355,0.402,0.291,0.305,0.293,0.62,0.395,1195,Stability,RS15_GEOSE,Medium,Prokaryote
S22A1_HUMAN_Yee_2023_abundance,0.507,0.55,0.564,0.573,0.584,0.597,0.38,0.511,0.608,0.607,0.597,0.621,0.655,0.484,0.537,0.558,0.626,0.599,0.566,0.038,0.492,0.596,0.606,0.59,0.526,0.611,0.629,0.6,0.557,0.582,0.571,0.444,0.605,0.33,0.522,0.596,0.59,0.566,0.627,0.631,0.618,0.633,0.633,0.504,0.274,0.584,0.555,0.44,0.547,0.534,0.176,0.582,0.571,0.574,0.594,0.607,0.597,0.594,0.599,0.592,0.609,0.63,0.58,0.606,0.502,0.416,0.465,0.494,0.477,0.638,0.502,0.584,0.64,0.525,0.596,0.643,0.607,0.65,0.546,0.559,0.602,0.621,0.595,0.598,0.626,0.55,0.358,0.152,0.55,0.381,0.426,0.47,0.543,0.606,0.603,0.618,0.626,9803,Expression,S22A1_HUMAN,Medium,Human
S22A1_HUMAN_Yee_2023_activity,0.45,0.517,0.557,0.57,0.553,0.566,0.347,0.508,0.562,0.557,0.553,0.572,0.614,0.448,0.48,0.477,0.575,0.547,0.525,0.03,0.488,0.579,0.57,0.561,0.526,0.584,0.597,0.567,0.533,0.578,0.596,0.508,0.595,0.299,0.504,0.577,0.568,0.527,0.59,0.591,0.586,0.604,0.601,0.458,0.238,0.561,0.501,0.408,0.527,0.503,0.169,0.542,0.52,0.514,0.539,0.56,0.542,0.542,0.559,0.552,0.56,0.542,0.5,0.533,0.458,0.359,0.394,0.418,0.417,0.575,0.431,0.599,0.579,0.555,0.55,0.601,0.568,0.613,0.55,0.499,0.513,0.558,0.579,0.562,0.555,0.513,0.37,0.098,0.492,0.387,0.454,0.479,0.556,0.59,0.561,0.621,0.521,10094,Activity,S22A1_HUMAN,Medium,Human
SAV1_MOUSE_Tsuboyama_2023_2YSB,0.137,0.201,0.394,0.373,0.407,0.399,0.426,0.503,0.41,0.43,0.481,0.472,0.508,0.238,0.496,0.496,0.512,0.52,0.406,0.43,0.491,0.458,0.449,0.479,0.524,0.519,0.476,0.491,0.482,0.518,0.469,0.419,0.465,0.353,0.424,0.497,0.499,0.431,0.498,0.489,0.411,0.443,0.444,0.503,-0.042,0.545,0.531,0.336,0.332,0.443,0.502,0.454,0.348,0.234,0.367,0.362,0.395,0.392,0.445,0.426,0.387,0.575,0.607,0.529,0.326,0.596,0.581,0.584,0.561,0.534,0.585,0.521,0.534,0.554,0.539,0.509,0.55,0.516,0.374,0.616,0.548,0.524,0.539,0.433,0.479,0.452,0.096,0.069,0.459,0.083,0.277,0.427,0.418,0.534,0.521,0.554,0.515,965,Stability,SAV1_MOUSE,High,Eukaryote
SBI_STAAM_Tsuboyama_2023_2JVG,0.232,0.225,0.38,0.345,0.44,0.403,0.205,0.178,0.481,0.533,0.323,0.268,0.297,0.23,0.266,0.376,0.573,0.658,0.318,0.359,0.228,0.263,0.259,0.235,0.21,0.228,0.221,0.245,0.339,0.549,0.582,0.487,0.65,0.169,0.195,0.2,0.225,0.297,0.305,0.314,0.355,0.368,0.382,0.262,0.228,0.316,0.305,0.664,0.627,0.687,0.616,0.529,0.526,0.561,0.55,0.545,0.547,0.569,0.565,0.558,0.561,0.683,0.571,0.341,0.398,0.52,0.689,0.598,0.62,0.657,0.662,0.562,0.704,0.616,0.637,0.554,0.65,0.555,0.37,0.708,0.57,0.576,0.289,0.461,0.277,0.062,-0.085,0.077,0.499,0.226,0.244,0.236,0.276,0.309,0.306,0.645,0.552,1025,Stability,SBI_STAAM,Medium,Prokaryote
SC6A4_HUMAN_Young_2021,0.387,0.456,0.423,0.433,0.504,0.522,0.352,0.507,0.562,0.574,0.545,0.531,0.542,0.159,0.327,0.502,0.543,0.548,0.524,0.555,0.498,0.511,0.5,0.496,0.512,0.52,0.518,0.525,0.511,0.541,0.463,0.36,0.528,0.342,0.513,0.512,0.491,0.53,0.542,0.53,0.549,0.555,0.545,0.489,0.112,0.549,0.531,0.467,0.527,0.501,0.182,0.516,0.526,0.535,0.543,0.545,0.536,0.536,0.538,0.526,0.546,0.578,0.528,0.547,0.42,0.319,0.33,0.361,0.348,0.492,0.368,0.547,0.534,0.509,0.541,0.561,0.537,0.558,0.494,0.522,0.552,0.559,0.547,0.553,0.533,0.499,0.389,0.044,0.46,0.408,0.458,0.503,0.494,0.498,0.506,0.548,0.561,11576,Activity,SC6A4_HUMAN,Medium,Human
SCIN_STAAR_Tsuboyama_2023_2QFF,0.083,0.14,0.261,0.264,0.3,0.272,0.154,0.065,0.271,0.258,0.299,0.298,0.269,0.208,0.305,0.279,0.346,0.406,0.414,0.25,0.106,0.162,0.134,0.144,0.155,0.194,0.152,0.2,0.215,0.229,0.296,0.208,0.269,-0.012,0.072,0.104,0.187,0.132,0.132,0.156,0.245,0.235,0.255,0.231,0.177,0.3,0.269,0.525,0.527,0.517,0.477,0.438,0.442,0.437,0.48,0.422,0.478,0.43,0.43,0.391,0.454,0.62,0.513,0.232,0.21,0.559,0.52,0.489,0.552,0.554,0.513,0.379,0.513,0.455,0.49,0.442,0.542,0.461,0.057,0.604,0.295,0.316,0.137,0.076,0.2,0.129,0.088,-0.016,0.234,0.247,0.255,0.262,0.262,0.231,0.281,0.49,0.422,1212,Stability,SCIN_STAAR,High,Prokaryote
SCN5A_HUMAN_Glazer_2019,0.13,0.131,0.162,0.162,0.153,0.158,0.13,-0.014,0.163,0.18,0.141,0.217,0.135,0.216,0.177,0.156,0.183,0.152,0.125,0.126,0.106,0.143,0.151,0.127,0.124,0.106,0.093,0.107,0.167,0.144,0.186,0.181,0.106,0.095,0.075,0.068,0.069,0.095,0.086,0.086,0.14,0.14,0.152,0.086,0.137,0.165,0.154,0.03,0.092,0.053,0.014,0.127,0.16,0.157,0.127,0.105,0.135,0.143,0.136,0.169,0.146,0.232,0.168,0.103,0.083,0.292,0.256,0.361,0.455,0.165,0.464,0.134,0.179,0.166,0.134,0.155,0.104,0.141,0.26,0.03,0.223,0.115,0.157,0.211,0.135,0.112,0.133,0.134,0.19,0.069,0.088,0.078,0.036,0.086,0.075,0.137,0.145,224,OrganismalFitness,SCN5A_HUMAN,Medium,Human
SDA_BACSU_Tsuboyama_2023_1PV0,0.631,0.646,0.615,0.619,0.647,0.65,0.001,0.303,0.456,0.472,0.606,0.418,0.466,0.249,0.274,0.608,0.594,0.598,0.596,0.53,0.026,0.067,0.003,0.238,0.081,0.123,0.045,0.119,0.214,0.64,0.604,0.581,0.538,-0.165,0.01,0.26,0.107,0.607,0.613,0.368,0.652,0.65,0.486,0.037,-0.079,0.336,0.011,0.434,0.41,0.608,0.597,0.65,0.641,0.588,0.647,0.63,0.613,0.622,0.623,0.653,0.633,0.639,0.636,0.546,0.542,0.706,0.535,0.703,0.682,0.726,0.748,0.641,0.722,0.641,0.611,0.639,0.6,0.638,0.584,0.553,0.616,0.56,0.472,0.518,0.548,0.27,-0.022,-0.041,0.6,0.161,0.15,0.207,0.094,0.139,0.226,0.61,0.582,2770,Stability,SDA_BACSU,Medium,Prokaryote
SERC_HUMAN_Xie_2023,0.375,0.483,0.544,0.544,0.52,0.53,0.013,0.456,0.57,0.576,0.518,0.541,0.547,0.183,0.407,0.529,0.558,0.577,0.543,0.535,0.492,0.511,0.513,0.484,0.5,0.53,0.518,0.534,0.504,0.506,0.516,0.469,0.547,0.192,0.513,0.528,0.519,0.528,0.54,0.544,0.548,0.551,0.552,0.319,0.031,0.54,0.46,0.382,0.461,0.352,0.189,0.539,0.524,0.54,0.551,0.558,0.548,0.553,0.55,0.543,0.561,0.562,0.478,0.546,0.404,0.258,0.332,0.334,0.358,0.482,0.374,0.516,0.49,0.495,0.551,0.569,0.542,0.566,0.485,0.525,0.548,0.583,0.545,0.568,0.57,0.486,0.343,0.084,0.507,0.488,0.498,0.523,0.514,0.527,0.52,0.564,0.551,1914,OrganismalFitness,SERC_HUMAN,High,Human
SHOC2_HUMAN_Kwon_2022,0.208,0.328,0.378,0.383,0.37,0.379,0.226,0.36,0.424,0.422,0.395,0.384,0.41,0.242,0.249,0.267,0.426,0.388,0.29,0.388,0.262,0.363,0.385,0.355,0.267,0.394,0.39,0.4,0.358,0.407,0.416,0.366,0.403,0.153,0.254,0.308,0.376,0.264,0.302,0.367,0.367,0.367,0.396,0.262,0.236,0.421,0.291,0.303,0.358,0.286,0.095,0.373,0.367,0.387,0.39,0.396,0.398,0.381,0.392,0.384,0.398,0.322,0.286,0.388,0.294,0.305,0.318,0.322,0.306,0.356,0.322,0.415,0.35,0.382,0.394,0.41,0.407,0.419,0.305,0.297,0.288,0.295,0.308,0.409,0.402,0.39,0.297,0.255,0.335,0.233,0.233,0.234,0.216,0.254,0.242,0.392,0.406,10972,OrganismalFitness,SHOC2_HUMAN,Medium,Human
SOX30_HUMAN_Tsuboyama_2023_7JJK,0.225,0.241,0.235,0.242,0.282,0.273,0.369,0.17,0.21,0.246,0.254,0.335,0.336,0.298,0.396,0.333,0.322,0.262,0.261,0.223,0.166,0.167,0.162,0.19,0.264,0.247,0.202,0.253,0.189,0.231,0.087,0.06,0.227,0.222,0.133,0.267,0.229,0.217,0.241,0.234,0.275,0.274,0.262,0.271,0.15,0.208,0.356,0.526,0.346,0.53,0.464,0.333,0.38,0.348,0.333,0.326,0.385,0.333,0.334,0.334,0.356,0.333,0.466,0.296,0.352,0.623,0.628,0.654,0.602,0.395,0.616,0.249,0.379,0.365,0.376,0.331,0.414,0.355,0.207,0.475,0.284,0.25,0.21,0.135,0.203,0.187,0.122,0.14,0.133,0.229,0.304,0.356,0.369,0.419,0.342,0.463,0.314,1010,Stability,SOX30_HUMAN,High,Human
SPA_STAAU_Tsuboyama_2023_1LP1,0.432,0.509,0.518,0.501,0.552,0.549,-0.093,0.495,0.409,0.408,0.393,-0.041,0.001,-0.032,-0.033,-0.064,0.005,-0.01,0.02,0.514,-0.154,0.032,0.205,0.105,-0.081,-0.041,0.057,0.338,0.428,0.564,0.432,0.442,0.411,-0.034,-0.011,0.001,0.066,0.437,0.43,0.427,0.548,0.547,0.536,-0.137,-0.087,-0.071,-0.009,0.512,0.453,0.705,0.56,0.52,0.511,0.493,0.534,0.498,0.515,0.51,0.501,0.504,0.513,0.546,0.414,0.495,0.424,0.328,0.524,0.515,0.413,0.617,0.616,0.609,0.664,0.662,0.422,0.599,0.506,0.628,0.528,0.681,-0.125,0.004,0.098,0.4,0.124,-0.072,-0.015,-0.235,0.427,-0.068,-0.016,0.042,-0.031,0.051,0.067,0.702,0.528,2105,Stability,SPA_STAAU,Medium,Prokaryote
SPG1_STRSG_Olson_2014,0.239,0.282,-0.004,0.006,0.247,0.272,-0.041,0.017,-0.038,0.171,0.305,0.237,0.192,0.28,0.232,0.264,0.301,0.251,0.337,0.278,0.252,0.216,0.214,0.208,0.232,0.222,0.218,0.239,0.354,0.283,0.478,0.494,0.335,0.111,0.223,0.175,0.279,0.243,0.204,0.289,0.229,0.188,0.29,-0.092,-0.112,0.158,0.004,0.362,0.306,0.423,0.147,0.38,0.315,0.364,0.414,0.414,0.36,0.418,0.417,0.41,0.407,0.387,0.374,0.36,0.336,0.736,0.776,0.787,0.778,0.743,0.773,0.402,0.722,0.408,0.388,0.405,0.443,0.437,0.243,0.412,0.302,0.296,0.257,0.313,0.32,0.215,-0.056,0.115,0.341,0.205,0.181,0.198,0.192,0.234,0.266,0.538,0.291,536962,Binding,SPG1_STRSG,Low,Prokaryote
SPG1_STRSG_Wu_2016,-0.051,0.025,0.048,0.048,0.036,0.042,0.036,-0.048,0.17,0.171,0.121,0.086,0.059,0.03,0.097,0.118,0.128,0.165,0.199,0.083,-0.012,-0.033,-0.051,-0.023,-0.061,0.016,-0.014,-0.031,-0.031,0.102,0.146,0.125,0.223,-0.083,0.001,-0.085,-0.024,0.039,0.013,0.021,0.044,0.027,0.027,-0.013,-0.099,0.04,-0.026,0.091,0.023,0.18,0.089,0.144,0.136,0.132,0.176,0.156,0.131,0.194,0.167,0.177,0.159,0.171,0.114,0.114,0.154,0.3,0.283,0.297,0.343,0.247,0.31,0.121,0.239,0.149,0.161,0.114,0.166,0.118,0.037,0.144,0.138,0.097,0.091,0.117,0.117,0.011,-0.001,-0.039,0.072,-0.028,-0.007,-0.038,-0.037,0.043,0.023,0.347,0.16,149360,Binding,SPG1_STRSG,Medium,Prokaryote
SPG2_STRSG_Tsuboyama_2023_5UBS,0.439,0.517,0.496,0.539,0.569,0.565,0.325,0.309,0.543,0.478,0.501,0.437,0.409,0.366,0.432,0.451,0.5,0.504,0.528,0.507,0.388,0.433,0.436,0.392,0.343,0.465,0.356,0.485,0.501,0.614,0.561,0.536,0.584,-0.192,0.356,0.44,0.462,0.294,0.335,0.382,0.561,0.562,0.569,0.253,0.089,0.286,0.24,0.447,0.369,0.704,0.57,0.564,0.566,0.584,0.592,0.569,0.595,0.588,0.61,0.584,0.589,0.598,0.549,0.555,0.41,0.757,0.757,0.764,0.755,0.722,0.795,0.662,0.69,0.689,0.593,0.632,0.634,0.653,0.366,0.656,0.478,0.493,0.465,0.499,0.486,0.228,-0.273,0.038,0.481,0.38,0.474,0.456,0.519,0.497,0.489,0.737,0.628,1451,Stability,SPG2_STRSG,Medium,Prokaryote
SPIKE_SARS2_Starr_2020_binding,0.158,0.205,0.062,0.151,0.249,0.252,-0.046,0.369,0.356,0.36,-0.002,-0.064,-0.039,-0.049,-0.036,-0.022,-0.018,-0.008,0.038,0.337,0.305,0.368,0.357,0.364,0.384,0.347,0.315,0.378,0.319,0.247,0.324,0.357,0.362,0.171,0.338,0.328,0.355,0.334,0.325,0.317,0.356,0.346,0.341,-0.036,-0.013,-0.022,-0.008,0.517,0.483,0.405,0.16,0.224,0.241,0.226,0.297,0.251,0.301,0.258,0.279,0.228,0.279,0.357,0.159,0.315,0.135,0.468,0.507,0.51,0.509,0.549,0.541,0.441,0.547,0.482,0.348,0.366,0.408,0.402,0.358,0.448,-0.042,-0.036,-0.031,-0.003,0.084,0.407,0.286,0.027,0.118,0.377,0.386,0.379,0.345,0.365,0.334,0.44,0.383,3802,Binding,SPIKE_SARS2,Medium,Virus
SPIKE_SARS2_Starr_2020_expression,0.2,0.314,0.165,0.279,0.445,0.45,-0.016,0.352,0.413,0.446,0.05,-0.023,0.004,-0.026,0.001,0.01,0.012,0.018,0.072,0.355,0.317,0.382,0.374,0.387,0.379,0.367,0.322,0.397,0.328,0.359,0.313,0.346,0.365,0.178,0.344,0.346,0.383,0.361,0.361,0.367,0.451,0.455,0.475,0.005,0.022,0.024,0.041,0.561,0.533,0.465,0.187,0.321,0.354,0.33,0.422,0.379,0.413,0.384,0.392,0.363,0.405,0.498,0.266,0.498,0.25,0.511,0.525,0.587,0.537,0.605,0.577,0.502,0.61,0.553,0.462,0.545,0.527,0.578,0.423,0.521,-0.006,0.01,0.02,0.067,0.103,0.433,0.382,0.012,0.156,0.42,0.417,0.419,0.416,0.382,0.372,0.525,0.506,3798,Expression,SPIKE_SARS2,Medium,Virus
SPTN1_CHICK_Tsuboyama_2023_1TUD,0.572,0.613,0.647,0.599,0.632,0.615,0.23,0.524,0.552,0.593,0.637,0.649,0.641,-0.133,0.619,0.627,0.637,0.726,0.657,0.624,0.578,0.643,0.604,0.589,0.589,0.613,0.652,0.563,0.601,0.621,0.631,0.632,0.683,0.457,0.508,0.57,0.548,0.629,0.641,0.621,0.623,0.628,0.618,0.488,-0.221,0.465,0.498,0.421,0.401,0.62,0.623,0.693,0.679,0.683,0.685,0.696,0.685,0.676,0.674,0.696,0.691,0.667,0.526,0.667,0.211,0.587,0.546,0.576,0.704,0.762,0.744,0.701,0.77,0.662,0.656,0.662,0.691,0.673,0.686,0.62,0.65,0.664,0.546,0.576,0.623,0.562,0.352,0.413,0.514,0.302,0.258,0.459,0.416,0.543,0.568,0.708,0.595,3201,Stability,SPTN1_CHICK,High,Eukaryote
SQSTM_MOUSE_Tsuboyama_2023_2RRU,0.399,0.522,0.597,0.61,0.604,0.604,0.086,0.449,0.565,0.592,0.514,0.373,0.503,0.186,0.442,0.529,0.618,0.64,0.527,0.607,0.218,0.474,0.49,0.505,0.345,0.544,0.569,0.506,0.538,0.623,0.566,0.526,0.668,0.155,0.194,0.444,0.518,0.502,0.54,0.589,0.614,0.604,0.625,0.209,0.119,0.582,0.583,0.651,0.626,0.629,0.619,0.626,0.582,0.635,0.62,0.634,0.628,0.634,0.61,0.603,0.639,0.682,0.514,0.625,0.445,0.566,0.559,0.644,0.621,0.665,0.689,0.683,0.682,0.691,0.645,0.674,0.676,0.688,0.518,0.716,0.569,0.578,0.409,0.535,0.528,0.112,0.133,0.132,0.511,0.135,0.08,0.26,0.487,0.517,0.548,0.761,0.665,707,Stability,SQSTM_MOUSE,Medium,Eukaryote
SR43C_ARATH_Tsuboyama_2023_2N88,0.596,0.658,0.684,0.681,0.693,0.684,-0.19,0.508,0.638,0.61,0.702,0.639,0.654,-0.267,0.662,0.702,0.675,0.698,0.681,0.634,-0.109,0.377,0.382,0.504,0.493,0.575,0.607,0.608,0.61,0.665,0.674,0.635,0.662,0.359,0.039,0.189,0.368,0.667,0.669,0.673,0.685,0.689,0.68,0.575,-0.296,0.703,0.618,0.214,0.637,0.731,0.716,0.677,0.673,0.67,0.692,0.696,0.68,0.668,0.669,0.685,0.684,0.788,0.744,0.658,0.047,0.61,0.709,0.761,0.729,0.674,0.662,0.694,0.693,0.71,0.701,0.706,0.747,0.73,0.653,0.751,0.707,0.724,0.677,0.67,0.68,0.488,0.286,-0.29,0.679,-0.241,-0.082,0.29,0.268,0.59,0.55,0.741,0.676,1583,Stability,SR43C_ARATH,High,Eukaryote
SRBS1_HUMAN_Tsuboyama_2023_2O2W,0.36,0.511,0.696,0.694,0.723,0.718,0.549,0.362,0.743,0.742,0.628,0.664,0.7,0.498,0.713,0.731,0.734,0.673,0.694,0.653,0.679,0.649,0.653,0.62,0.642,0.637,0.659,0.63,0.607,0.694,0.696,0.658,0.701,0.577,0.597,0.637,0.645,0.66,0.697,0.705,0.701,0.727,0.728,0.388,0.084,0.538,0.532,0.579,0.538,0.64,0.661,0.751,0.731,0.734,0.736,0.746,0.741,0.735,0.735,0.74,0.75,0.707,0.689,0.722,0.487,0.609,0.679,0.714,0.699,0.802,0.724,0.718,0.796,0.753,0.68,0.734,0.697,0.74,0.612,0.688,0.738,0.752,0.61,0.62,0.615,0.622,0.51,0.629,0.581,0.566,0.616,0.626,0.596,0.676,0.666,0.783,0.74,1556,Stability,SRBS1_HUMAN,High,Human
SRC_HUMAN_Ahler_2019,0.526,0.508,0.465,0.465,0.496,0.507,0.532,0.44,0.514,0.532,0.469,0.561,0.585,0.447,0.486,0.49,0.555,0.515,0.467,0.484,0.439,0.413,0.421,0.373,0.437,0.46,0.438,0.422,0.33,0.542,0.578,0.574,0.531,0.431,0.41,0.411,0.348,0.502,0.502,0.492,0.521,0.52,0.516,0.567,0.397,0.487,0.546,0.309,0.296,0.409,0.098,0.517,0.495,0.492,0.517,0.524,0.521,0.517,0.527,0.524,0.532,0.506,0.479,0.572,0.446,0.553,0.599,0.607,0.638,0.624,0.638,0.536,0.628,0.492,0.517,0.545,0.533,0.552,0.519,0.459,0.551,0.537,0.425,0.319,0.282,0.355,0.351,0.377,0.155,0.487,0.47,0.461,0.409,0.394,0.345,0.565,0.567,3372,Activity,SRC_HUMAN,Medium,Human
SRC_HUMAN_Chakraborty_2023_binding-DAS_25uM,0.435,0.427,0.41,0.433,0.441,0.437,0.454,0.401,0.458,0.454,0.403,0.486,0.506,0.358,0.39,0.393,0.465,0.426,0.409,0.397,0.372,0.35,0.354,0.309,0.37,0.395,0.364,0.35,0.257,0.456,0.498,0.495,0.442,0.36,0.339,0.335,0.28,0.414,0.411,0.401,0.443,0.441,0.437,0.475,0.316,0.423,0.458,0.238,0.246,0.324,0.046,0.434,0.408,0.412,0.437,0.441,0.438,0.432,0.442,0.447,0.447,0.431,0.391,0.479,0.369,0.484,0.52,0.526,0.564,0.54,0.556,0.454,0.542,0.418,0.429,0.461,0.442,0.467,0.434,0.369,0.472,0.464,0.379,0.272,0.245,0.291,0.287,0.314,0.134,0.416,0.403,0.383,0.343,0.303,0.268,0.468,0.479,3637,Activity,SRC_HUMAN,Medium,Human
SRC_HUMAN_Nguyen_2022,0.428,0.426,0.413,0.428,0.429,0.425,0.442,0.405,0.357,0.411,0.401,0.483,0.506,0.342,0.378,0.387,0.471,0.443,0.415,0.396,0.373,0.344,0.35,0.306,0.381,0.397,0.372,0.358,0.269,0.453,0.493,0.484,0.443,0.355,0.348,0.343,0.282,0.416,0.412,0.399,0.44,0.437,0.43,0.477,0.304,0.427,0.466,0.221,0.227,0.31,0.063,0.439,0.405,0.409,0.432,0.441,0.433,0.434,0.444,0.441,0.445,0.43,0.382,0.472,0.376,0.458,0.508,0.51,0.553,0.529,0.543,0.451,0.531,0.402,0.431,0.457,0.445,0.462,0.437,0.355,0.466,0.459,0.377,0.275,0.232,0.296,0.295,0.31,0.148,0.41,0.398,0.391,0.347,0.317,0.284,0.472,0.448,3366,OrganismalFitness,SRC_HUMAN,Medium,Human
SUMO1_HUMAN_Weile_2017,0.369,0.373,0.419,0.438,0.48,0.478,0.13,0.425,0.449,0.386,0.433,0.467,0.51,0.25,0.496,0.533,0.509,0.38,0.34,0.517,0.217,0.414,0.443,0.43,0.468,0.386,0.46,0.431,0.333,0.438,0.46,0.445,0.524,0.212,0.245,0.473,0.329,0.405,0.511,0.41,0.452,0.522,0.463,0.49,0.086,0.395,0.527,0.497,0.428,0.509,0.412,0.492,0.453,0.5,0.5,0.493,0.517,0.479,0.498,0.491,0.511,0.479,0.524,0.487,0.463,0.527,0.531,0.566,0.572,0.496,0.563,0.533,0.527,0.54,0.496,0.527,0.529,0.546,0.529,0.574,0.386,0.373,0.483,0.343,0.376,0.351,0.433,-0.024,0.306,0.165,0.312,0.422,0.45,0.43,0.399,0.505,0.393,1700,OrganismalFitness,SUMO1_HUMAN,High,Human
SYUA_HUMAN_Newberry_2020,0.103,0.111,0.119,0.132,0.131,0.139,0.131,0.212,0.171,0.162,0.234,0.242,0.233,0.105,0.142,0.15,0.137,0.206,0.205,0.22,0.138,0.203,0.155,0.141,0.086,0.151,0.167,0.105,0.136,0.227,0.205,0.189,0.224,0.005,0.137,0.197,0.181,0.124,0.176,0.159,0.134,0.166,0.156,0.115,0.068,0.16,0.155,-0.052,0.046,-0.06,-0.074,0.069,0.056,0.053,0.088,0.129,0.098,0.127,0.102,0.144,0.098,-0.011,-0.045,0.171,-0.073,0.328,0.371,0.336,0.453,0.514,0.366,0.219,0.501,-0.02,0.119,0.146,0.131,0.155,0.138,0.0,0.182,0.184,0.164,0.12,0.132,0.168,0.141,0.042,0.14,0.08,0.082,0.104,0.124,0.172,0.215,0.358,0.21,2497,OrganismalFitness,SYUA_HUMAN,Medium,Human
TADBP_HUMAN_Bolognesi_2019,0.097,0.061,0.1,0.096,0.08,0.08,0.291,-0.018,0.077,0.072,0.013,0.051,0.048,0.121,0.047,0.021,-0.12,-0.028,0.053,-0.075,0.158,0.063,-0.011,-0.006,0.206,0.082,0.006,0.023,-0.014,0.036,0.088,0.112,0.108,-0.051,0.226,0.273,0.121,0.142,0.185,0.121,0.105,0.129,0.109,0.121,0.212,-0.002,0.078,0.271,0.033,0.223,0.059,0.105,0.013,0.004,0.04,0.002,0.034,0.045,-0.011,-0.079,0.021,0.054,0.121,0.096,0.137,0.551,0.598,0.575,0.562,0.627,0.606,-0.008,0.604,0.153,-0.12,-0.024,-0.12,-0.024,0.084,0.108,-0.012,0.086,0.038,-0.014,0.016,0.053,-0.014,-0.045,0.095,0.214,0.151,0.251,0.164,-0.009,0.034,0.223,0.067,1196,OrganismalFitness,TADBP_HUMAN,Low,Human
TAT_HV1BR_Fernandes_2016,0.293,0.201,0.255,0.268,0.319,0.3,-0.09,0.397,0.274,0.288,0.185,0.343,0.342,-0.034,-0.008,-0.005,0.017,-0.057,0.044,0.203,0.379,0.364,0.396,0.398,0.394,0.269,0.136,0.246,0.223,0.368,0.405,0.387,0.372,0.283,0.385,0.211,0.203,0.379,0.263,0.237,0.366,0.295,0.268,0.005,-0.054,0.292,0.181,0.23,0.284,0.344,0.207,0.114,0.134,0.142,0.137,0.116,0.133,0.12,0.117,0.117,0.134,0.157,0.116,0.323,0.131,0.44,0.536,0.52,0.569,0.419,0.577,0.389,0.424,0.428,0.148,0.27,0.154,0.276,0.323,0.25,0.45,-0.033,0.218,0.287,0.253,0.265,0.112,-0.137,0.257,0.462,0.424,0.43,0.399,0.37,0.28,0.376,0.324,1577,OrganismalFitness,TAT_HV1BR,High,Virus
TCRG1_MOUSE_Tsuboyama_2023_1E0L,0.576,0.615,0.644,0.655,0.66,0.662,0.696,0.292,0.677,0.708,0.591,0.739,0.75,0.724,0.707,0.784,0.769,0.707,0.745,0.577,0.49,0.552,0.57,0.609,0.604,0.613,0.66,0.648,0.597,0.68,0.64,0.595,0.669,0.642,0.485,0.619,0.669,0.688,0.715,0.71,0.68,0.712,0.695,0.753,0.184,0.629,0.752,0.68,0.596,0.774,0.759,0.721,0.697,0.657,0.757,0.733,0.763,0.723,0.738,0.71,0.735,0.79,0.774,0.762,0.497,0.736,0.725,0.568,0.742,0.688,0.681,0.688,0.72,0.775,0.762,0.746,0.791,0.764,0.662,0.785,0.761,0.747,0.715,0.725,0.554,0.73,0.638,0.481,0.401,0.282,0.535,0.547,0.667,0.644,0.685,0.677,0.642,1058,Stability,TCRG1_MOUSE,Medium,Eukaryote
THO1_YEAST_Tsuboyama_2023_2WQG,0.309,0.397,0.482,0.473,0.483,0.481,0.072,0.061,0.523,0.52,0.511,0.502,0.532,0.186,0.557,0.548,0.513,0.532,0.546,0.515,-0.047,0.332,0.349,0.305,0.351,0.383,0.279,0.423,0.534,0.543,0.526,0.512,0.561,0.48,0.003,0.403,0.337,0.446,0.505,0.495,0.472,0.51,0.511,0.301,0.114,0.463,0.389,0.504,0.484,0.561,0.597,0.555,0.546,0.566,0.573,0.584,0.548,0.561,0.551,0.545,0.561,0.502,0.483,0.545,0.142,0.682,0.597,0.629,0.649,0.554,0.685,0.556,0.55,0.559,0.535,0.526,0.553,0.535,0.478,0.642,0.581,0.56,0.507,0.513,0.561,0.501,0.282,-0.008,0.553,0.312,0.376,0.316,0.389,0.56,0.558,0.59,0.549,1279,Stability,THO1_YEAST,High,Eukaryote
TNKS2_HUMAN_Tsuboyama_2023_5JRT,0.464,0.473,0.506,0.495,0.507,0.502,-0.099,0.392,0.573,0.576,0.472,0.538,0.526,0.044,0.547,0.589,0.525,0.529,0.533,0.466,0.262,0.361,0.429,0.394,0.395,0.455,0.385,0.395,0.436,0.528,0.484,0.451,0.538,0.25,0.061,0.312,0.333,0.535,0.523,0.517,0.541,0.518,0.518,0.343,-0.03,0.572,0.492,0.526,0.649,0.675,0.624,0.51,0.53,0.516,0.512,0.517,0.511,0.521,0.512,0.513,0.524,0.597,0.604,0.528,0.382,0.686,0.653,0.65,0.647,0.596,0.686,0.595,0.59,0.569,0.548,0.548,0.611,0.58,0.53,0.672,0.543,0.562,0.442,0.447,0.44,0.294,0.075,-0.031,0.432,-0.209,0.013,0.244,0.358,0.38,0.383,0.751,0.553,1479,Stability,TNKS2_HUMAN,High,Human
TPK1_HUMAN_Weile_2017,0.217,0.236,0.219,0.228,0.23,0.229,0.067,0.253,0.286,0.27,0.285,0.27,0.318,0.108,0.199,0.253,0.339,0.328,0.371,0.249,0.088,0.142,0.228,0.272,0.115,0.267,0.273,0.253,0.306,0.255,0.253,0.188,0.278,0.117,0.115,0.214,0.301,0.232,0.252,0.305,0.243,0.252,0.277,0.12,0.089,0.309,0.17,0.206,0.267,0.245,0.116,0.253,0.277,0.275,0.278,0.293,0.291,0.281,0.291,0.292,0.298,0.268,0.203,0.285,0.123,0.247,0.253,0.254,0.263,0.249,0.309,0.267,0.263,0.226,0.295,0.28,0.276,0.27,0.269,0.261,0.272,0.303,0.271,0.31,0.34,0.206,0.129,0.027,0.385,0.11,0.167,0.183,0.18,0.22,0.268,0.274,0.384,3181,OrganismalFitness,TPK1_HUMAN,Medium,Human
TPMT_HUMAN_Matreyek_2018,0.372,0.456,0.489,0.509,0.499,0.513,0.241,0.445,0.497,0.5,0.546,0.517,0.547,0.308,0.433,0.531,0.539,0.476,0.448,0.511,0.333,0.42,0.481,0.496,0.447,0.506,0.481,0.466,0.424,0.547,0.542,0.489,0.557,0.334,0.33,0.471,0.411,0.478,0.513,0.478,0.517,0.537,0.515,0.371,0.204,0.539,0.495,0.476,0.534,0.54,0.238,0.522,0.519,0.53,0.514,0.541,0.535,0.541,0.529,0.534,0.543,0.568,0.469,0.554,0.388,0.455,0.429,0.48,0.512,0.557,0.497,0.569,0.582,0.527,0.543,0.555,0.558,0.566,0.511,0.558,0.561,0.562,0.564,0.53,0.53,0.486,0.181,-0.031,0.467,0.372,0.444,0.427,0.486,0.512,0.499,0.579,0.545,3648,Expression,TPMT_HUMAN,Medium,Human
TPOR_HUMAN_Bridgford_2020,0.376,0.365,0.283,0.263,0.288,0.296,0.37,0.455,0.454,0.456,0.407,0.368,0.37,0.279,0.378,0.294,0.29,0.422,0.362,0.362,0.25,0.338,0.313,0.377,0.367,0.2,0.471,0.451,0.34,0.45,0.436,0.274,0.4,0.395,0.372,0.321,0.419,0.429,0.408,0.451,0.408,0.382,0.437,0.295,0.303,0.353,0.348,0.126,0.357,0.309,0.035,0.344,0.308,0.344,0.354,0.322,0.345,0.396,0.257,0.293,0.341,0.389,0.372,0.431,0.273,0.478,0.507,0.552,0.547,0.52,0.482,0.407,0.514,0.216,0.372,0.392,0.365,0.384,0.329,0.33,0.317,0.297,0.32,0.41,0.405,0.469,0.013,0.208,0.455,0.266,0.273,0.237,0.206,0.17,0.387,0.501,0.432,562,OrganismalFitness,TPOR_HUMAN,Low,Human
TRPC_SACS2_Chan_2017,0.575,0.606,0.558,0.574,0.575,0.585,0.173,0.499,0.655,0.671,0.621,0.611,0.643,0.325,0.539,0.618,0.653,0.632,0.601,0.592,0.421,0.564,0.508,0.575,0.498,0.499,0.558,0.521,0.524,0.529,0.59,0.52,0.618,0.221,0.52,0.555,0.558,0.575,0.598,0.591,0.59,0.612,0.601,0.434,0.072,0.612,0.498,0.321,0.512,0.507,0.122,0.593,0.594,0.582,0.646,0.614,0.615,0.621,0.63,0.614,0.636,0.626,0.578,0.617,0.549,0.616,0.667,0.659,0.687,0.601,0.687,0.526,0.62,0.561,0.614,0.63,0.619,0.631,0.581,0.591,0.629,0.673,0.614,0.661,0.655,0.352,0.07,0.019,0.641,0.529,0.525,0.556,0.585,0.55,0.609,0.604,0.649,1519,OrganismalFitness,TRPC_SACS2,Medium,Prokaryote
TRPC_THEMA_Chan_2017,0.405,0.45,0.394,0.411,0.416,0.417,0.395,0.434,0.471,0.47,0.439,0.478,0.506,0.327,0.47,0.503,0.464,0.47,0.499,0.43,0.336,0.399,0.395,0.455,0.437,0.421,0.369,0.387,0.478,0.39,0.427,0.365,0.437,0.14,0.329,0.46,0.448,0.39,0.442,0.438,0.418,0.445,0.442,0.397,0.14,0.461,0.395,0.253,0.386,0.393,0.075,0.459,0.41,0.431,0.462,0.463,0.409,0.439,0.441,0.418,0.454,0.504,0.491,0.479,0.418,0.569,0.642,0.556,0.627,0.478,0.596,0.391,0.463,0.353,0.456,0.461,0.455,0.457,0.388,0.467,0.479,0.521,0.499,0.517,0.48,0.415,0.116,0.085,0.463,0.423,0.412,0.377,0.461,0.425,0.435,0.48,0.492,1519,OrganismalFitness,TRPC_THEMA,Medium,Prokaryote
UBC9_HUMAN_Weile_2017,0.371,0.496,0.521,0.531,0.508,0.522,-0.042,0.403,0.512,0.519,0.42,0.477,0.509,0.001,0.004,0.403,0.473,0.518,0.538,0.557,0.22,0.405,0.445,0.419,0.42,0.479,0.471,0.449,0.442,0.484,0.454,0.432,0.513,0.071,0.233,0.403,0.428,0.327,0.452,0.475,0.443,0.517,0.54,0.277,-0.008,0.427,0.492,0.322,0.35,0.446,0.243,0.44,0.417,0.408,0.433,0.425,0.427,0.433,0.44,0.442,0.439,0.37,0.426,0.546,0.283,0.344,0.412,0.415,0.367,0.403,0.468,0.492,0.411,0.466,0.457,0.526,0.448,0.522,0.449,0.483,0.499,0.493,0.487,0.367,0.368,0.476,0.319,-0.091,0.254,0.208,0.282,0.391,0.445,0.477,0.466,0.528,0.511,2563,OrganismalFitness,UBC9_HUMAN,Medium,Human
UBE4B_HUMAN_Tsuboyama_2023_3L1X,0.325,0.443,0.464,0.467,0.466,0.466,0.051,0.346,0.379,0.415,0.391,0.453,0.449,0.347,0.42,0.49,0.46,0.467,0.477,0.421,0.142,0.353,0.357,0.364,0.345,0.374,0.343,0.322,0.355,0.486,0.475,0.453,0.448,0.441,0.079,0.11,0.255,0.383,0.385,0.329,0.472,0.477,0.424,0.359,-0.095,0.348,0.344,0.488,0.409,0.52,0.351,0.411,0.436,0.424,0.447,0.448,0.428,0.407,0.429,0.42,0.432,0.5,0.407,0.441,0.321,0.454,0.421,0.437,0.5,0.522,0.468,0.527,0.515,0.496,0.418,0.454,0.458,0.472,0.425,0.558,0.488,0.511,0.421,0.424,0.391,0.231,-0.034,-0.16,0.342,-0.066,-0.065,0.29,0.332,0.418,0.389,0.563,0.434,3622,Stability,UBE4B_HUMAN,High,Human
UBE4B_MOUSE_Starita_2013,0.412,0.417,0.454,0.468,0.463,0.47,0.078,0.089,0.392,0.394,0.361,0.447,0.471,0.399,0.463,0.459,0.459,0.351,0.349,0.383,0.122,0.324,0.337,0.3,0.444,0.376,0.395,0.376,0.289,0.433,0.437,0.396,0.451,0.091,0.026,0.096,0.262,0.419,0.351,0.39,0.467,0.454,0.472,0.409,0.041,0.42,0.458,0.307,0.393,-0.017,0.118,0.426,0.409,0.456,0.458,0.438,0.458,0.432,0.449,0.443,0.454,0.44,0.412,0.495,0.094,0.368,0.407,0.458,0.477,0.429,0.429,0.421,0.454,0.396,0.438,0.481,0.441,0.477,0.481,0.386,0.458,0.46,0.401,0.347,0.415,0.444,0.1,0.01,0.264,0.08,0.162,0.377,0.344,0.346,0.336,0.472,0.412,899,Activity,UBE4B_MOUSE,Low,Eukaryote
UBR5_HUMAN_Tsuboyama_2023_1I2T,0.442,0.55,0.54,0.538,0.566,0.577,0.152,0.251,0.498,0.528,0.528,0.425,0.511,0.226,0.226,0.158,0.197,0.591,0.601,0.476,0.422,0.414,0.467,0.514,0.473,0.462,0.495,0.488,0.492,0.557,0.497,0.388,0.602,0.288,0.304,0.455,0.401,0.484,0.519,0.502,0.592,0.594,0.583,0.133,0.121,0.422,0.209,0.557,0.439,0.637,0.574,0.56,0.588,0.597,0.609,0.599,0.612,0.589,0.605,0.585,0.6,0.661,0.597,0.58,0.129,0.672,0.715,0.659,0.675,0.719,0.699,0.579,0.706,0.555,0.508,0.599,0.505,0.609,0.469,0.719,0.565,0.584,0.523,0.475,0.531,0.472,0.455,0.205,0.482,0.205,0.366,0.41,0.376,0.402,0.479,0.702,0.558,1453,Stability,UBR5_HUMAN,Medium,Human
VG08_BPP22_Tsuboyama_2023_2GP8,0.228,0.314,0.228,0.246,0.266,0.255,0.256,0.064,0.371,0.392,0.623,0.544,0.562,0.36,0.514,0.601,0.655,0.611,0.653,0.167,0.395,0.474,0.458,0.531,0.419,0.425,0.41,0.467,0.516,0.487,0.51,0.386,0.448,0.038,0.307,0.473,0.464,0.343,0.415,0.464,0.336,0.403,0.409,0.469,0.295,0.552,0.483,0.458,0.561,0.543,0.505,0.652,0.626,0.661,0.661,0.664,0.691,0.634,0.658,0.684,0.674,0.619,0.6,0.305,0.419,0.543,0.665,0.641,0.665,0.603,0.659,0.45,0.614,0.471,0.666,0.541,0.664,0.526,0.345,0.658,0.56,0.576,0.525,0.568,0.588,0.149,0.066,0.045,0.668,0.312,0.353,0.441,0.545,0.511,0.545,0.566,0.407,723,Stability,VG08_BPP22,High,Virus
VILI_CHICK_Tsuboyama_2023_1YU5,0.284,0.422,0.594,0.63,0.634,0.637,0.162,0.54,0.553,0.59,0.673,0.63,0.673,0.371,0.316,0.652,0.662,0.589,0.478,0.592,0.293,0.431,0.601,0.524,0.424,0.575,0.494,0.482,0.579,0.599,0.701,0.694,0.665,0.322,0.346,0.515,0.521,0.487,0.564,0.563,0.634,0.659,0.642,0.272,0.283,0.426,0.421,0.542,0.433,0.775,0.702,0.672,0.658,0.666,0.658,0.653,0.665,0.649,0.656,0.652,0.662,0.685,0.798,0.644,0.449,0.601,0.742,0.798,0.805,0.816,0.83,0.593,0.799,0.677,0.61,0.644,0.65,0.664,0.534,0.781,0.659,0.648,0.625,0.618,0.633,0.696,0.518,0.461,0.564,0.162,0.141,0.318,0.407,0.423,0.604,0.724,0.64,2568,Stability,VILI_CHICK,High,Eukaryote
VKOR1_HUMAN_Chiasson_2020_abundance,0.409,0.416,0.402,0.422,0.437,0.437,0.245,0.396,0.501,0.52,0.438,0.447,0.474,0.251,0.443,0.5,0.493,0.484,0.472,0.464,0.286,0.298,0.396,0.43,0.368,0.471,0.463,0.437,0.442,0.481,0.383,0.288,0.489,0.09,0.256,0.364,0.505,0.462,0.483,0.548,0.476,0.492,0.538,0.236,0.18,0.464,0.384,0.446,0.441,0.49,0.279,0.52,0.49,0.53,0.543,0.53,0.513,0.526,0.508,0.525,0.533,0.494,0.479,0.463,0.4,0.54,0.545,0.543,0.566,0.597,0.584,0.472,0.593,0.382,0.518,0.505,0.516,0.503,0.436,0.483,0.446,0.46,0.458,0.449,0.463,0.419,0.089,-0.103,0.395,0.271,0.335,0.441,0.445,0.457,0.47,0.559,0.412,2695,Expression,VKOR1_HUMAN,Medium,Human
VKOR1_HUMAN_Chiasson_2020_activity,0.329,0.368,0.399,0.41,0.413,0.428,0.0,0.386,0.423,0.441,0.419,0.427,0.448,0.016,0.298,0.369,0.43,0.446,0.445,0.415,0.051,0.073,0.272,0.31,0.132,0.384,0.384,0.36,0.385,0.421,0.431,0.388,0.439,0.179,0.022,0.135,0.37,0.339,0.35,0.401,0.409,0.42,0.436,0.084,0.021,0.416,0.226,0.225,0.334,0.366,0.1,0.404,0.358,0.369,0.389,0.406,0.389,0.391,0.394,0.394,0.401,0.427,0.322,0.424,0.111,0.302,0.358,0.374,0.377,0.301,0.402,0.414,0.316,0.384,0.409,0.437,0.401,0.432,0.415,0.375,0.414,0.435,0.409,0.444,0.447,0.289,-0.016,0.063,0.34,0.035,0.213,0.342,0.328,0.407,0.429,0.429,0.368,697,Activity,VKOR1_HUMAN,Medium,Human
VRPI_BPT7_Tsuboyama_2023_2WNM,-0.119,0.043,0.164,0.194,0.078,0.119,0.082,0.147,0.366,0.356,0.498,0.368,0.374,0.252,0.41,0.507,0.587,0.612,0.468,0.128,-0.02,0.135,0.133,0.222,0.215,0.202,0.131,0.199,0.291,0.084,0.499,0.429,0.539,0.242,0.065,0.059,0.122,-0.039,-0.028,-0.057,0.064,0.083,0.006,0.254,0.056,0.501,0.357,0.589,0.557,0.593,0.606,0.612,0.592,0.633,0.639,0.622,0.641,0.615,0.63,0.604,0.64,0.662,0.582,0.472,0.401,0.608,0.69,0.581,0.637,0.663,0.631,0.356,0.598,0.453,0.639,0.479,0.645,0.462,0.002,0.668,0.627,0.631,0.557,0.545,0.56,0.002,0.04,0.009,0.54,0.289,0.196,0.25,0.325,0.375,0.474,0.547,0.504,1047,Stability,VRPI_BPT7,Medium,Virus
YAIA_ECOLI_Tsuboyama_2023_2KVT,0.291,0.602,0.572,0.596,0.599,0.591,-0.221,0.533,0.559,0.598,0.593,0.27,0.481,-0.107,0.173,0.572,0.625,0.684,0.684,0.591,-0.091,-0.182,-0.13,0.264,-0.125,-0.166,-0.231,-0.023,0.52,0.605,0.681,0.643,0.678,-0.06,-0.234,-0.064,0.502,0.349,0.359,0.528,0.572,0.569,0.604,-0.046,-0.261,0.208,-0.013,0.449,0.425,0.651,0.544,0.587,0.627,0.585,0.619,0.612,0.627,0.625,0.657,0.677,0.632,0.616,0.498,0.588,-0.035,0.607,0.513,0.526,0.619,0.792,0.743,0.662,0.753,0.709,0.648,0.657,0.668,0.671,0.441,0.752,0.229,0.39,0.106,0.162,0.505,-0.052,-0.222,-0.048,0.637,-0.074,0.059,0.358,0.314,0.395,0.496,0.744,0.634,1890,Stability,YAIA_ECOLI,Medium,Prokaryote
YAP1_HUMAN_Araya_2012,0.428,0.321,0.464,0.46,0.449,0.455,0.329,0.289,0.018,0.036,0.333,0.28,0.285,0.411,0.457,0.451,0.466,0.382,0.313,0.189,0.18,0.176,0.158,0.167,0.299,0.226,0.257,0.207,0.15,0.332,0.425,0.451,0.35,0.139,0.302,0.196,0.217,0.402,0.326,0.359,0.435,0.405,0.439,0.485,-0.104,0.335,0.486,0.34,0.362,0.383,0.197,0.446,0.379,0.432,0.426,0.417,0.412,0.415,0.441,0.444,0.438,0.386,0.422,0.421,0.408,0.586,0.579,0.58,0.575,0.549,0.59,0.392,0.546,0.519,0.458,0.493,0.459,0.496,0.376,0.439,0.396,0.298,0.253,0.166,0.102,0.296,0.351,0.144,0.061,0.384,0.322,0.284,0.243,0.247,0.232,0.48,0.365,10075,Binding,YAP1_HUMAN,Low,Human
YNZC_BACSU_Tsuboyama_2023_2JVD,0.596,0.61,0.595,0.618,0.604,0.609,0.492,0.394,0.591,0.583,0.673,0.649,0.667,0.584,0.621,0.65,0.658,0.631,0.63,0.525,0.488,0.534,0.612,0.604,0.594,0.611,0.587,0.59,0.643,0.594,0.586,0.547,0.6,0.568,0.573,0.567,0.544,0.665,0.634,0.621,0.669,0.624,0.63,0.446,0.353,0.536,0.448,0.483,0.562,0.68,0.65,0.701,0.649,0.665,0.687,0.7,0.691,0.687,0.676,0.679,0.69,0.638,0.76,0.591,0.39,0.729,0.717,0.739,0.748,0.719,0.745,0.592,0.693,0.618,0.693,0.675,0.703,0.68,0.578,0.671,0.589,0.576,0.655,0.602,0.642,0.591,-0.09,0.109,0.605,0.603,0.592,0.672,0.584,0.577,0.609,0.631,0.61,2300,Stability,YNZC_BACSU,Medium,Prokaryote