Ontology for Parasite Lifecycle
type: Ontology
version IRI: opl.owl
default language: en
contributor: Achchuthan Shanmugasundram
contributor: Kitsos Louis
contributor: Omar harb
contributor: Satya Sahoo
creator: Anna Protasio
creator: Chris J. Janse
creator: Chris Stoeckert
creator: Flora Logan
creator: Jie Zheng
creator: Priti Parikh
creator: Shahid M. Khan
date: 2010-08-04
description: The Ontology for Parasite Lifecycle (OPL) models the life cycle stage details of various parasites, including Trypanosoma sp., Leishmania major, and Plasmodium sp., etc. In addition to life cycle stages, the ontology also models necessary contextual details, such as host information, vector information, and anatomical location. OPL is based on the Basic Formal Ontology (BFO) and follows the rules set by the OBO Foundry consortium.
license: http://creativecommons.org/licenses/by/4.0/
comment: The Parasite Life Cycle ontology was developed as part of the NIH-funded "Semantics and Services enabled Problem Solving Environment for Tcruzi" project (Grant#1R01HL087795-01A1). The Kno.e.sis center, Computer Science and Engineering Department, Wright State University, Center for Bioinformatics, Department of Genetics, University of Pennsylvania School of Medicine, USA and the Tarleton Lab, Center for Tropical and Emerging Global Diseases (CTEGD), University of Georgia, USA collaborated to create this ontology. Resource page: http://knoesis.wright.edu/trykipedia
version info: 2023-06-23

BFO OWL specification label
type: AnnotationProperty
definition: Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification.
curator note: Really of interest to developers only
sub property of: label

BFO CLIF specification label
type: AnnotationProperty
definition: Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2
definition source: Person:Alan Ruttenberg
curator note: Really of interest to developers only
sub property of: label

editor preferred term
type: AnnotationProperty
editor preferred term: editor preferred term
has curation status: ready for release
definition: The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English)
term editor: PERSON:Daniel Schober
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>

example of usage
type: AnnotationProperty
editor preferred term: example of usage
has curation status: ready for release
definition: A phrase describing how a term should be used and/or a citation to a work which uses it. May also include other kinds of examples that facilitate immediate understanding, such as widely know prototypes or instances of a class, or cases where a relation is said to hold.
term editor: PERSON:Daniel Schober
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>

in branch
type: AnnotationProperty
editor preferred term: in branch
definition: An annotation property indicating which module the terms belong to. This is currently experimental and not implemented yet.
term editor: GROUP:OBI
definition source: OBI_0000277

has curation status
type: AnnotationProperty
editor preferred term: has curation status
term editor: PERSON:Alan Ruttenberg
term editor: PERSON:Bill Bug
term editor: PERSON:Melanie Courtot

definition
type: AnnotationProperty
editor preferred term: definition
has curation status: ready for release
definition: The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions.
editor note: 2012-04-05: Barry Smith The official OBI definition, explaining the meaning of a class or property: 'Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions' is terrible. Can you fix to something like: A statement of necessary and sufficient conditions explaining the meaning of an expression referring to a class or property. Alan Ruttenberg Your proposed definition is a reasonable candidate, except that it is very common that necessary and sufficient conditions are not given. Mostly they are necessary, occasionally they are necessary and sufficient or just sufficient. Often they use terms that are not themselves defined and so they effectively can't be evaluated by those criteria. On the specifics of the proposed definition: We don't have definitions of 'meaning' or 'expression' or 'property'. For 'reference' in the intended sense I think we use the term 'denotation'. For 'expression', I think we you mean symbol, or identifier. For 'meaning' it differs for class and property. For class we want documentation that let's the intended reader determine whether an entity is instance of the class, or not. For property we want documentation that let's the intended reader determine, given a pair of potential relata, whether the assertion that the relation holds is true. The 'intended reader' part suggests that we also specify who, we expect, would be able to understand the definition, and also generalizes over human and computer reader to include textual and logical definition. Personally, I am more comfortable weakening definition to documentation, with instructions as to what is desirable. We also have the outstanding issue of how to aim different definitions to different audiences. A clinical audience reading chebi wants a different sort of definition documentation/definition from a chemistry trained audience, and similarly there is a need for a definition that is adequate for an ontologist to work with.
term editor: PERSON:Daniel Schober
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>

editor note
type: AnnotationProperty
editor preferred term: editor note
has curation status: ready for release
definition: An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology.
term editor: PERSON:Daniel Schober
definition source: GROUP:OBI:<http://purl.obofoundry.org/obo/obi>

term editor
type: AnnotationProperty
editor preferred term: term editor
has curation status: ready for release
definition: Name of editor entering the term in the file. The term editor is a point of contact for information regarding the term. The term editor may be, but is not always, the author of the definition, which may have been worked upon by several people
editor note: 20110707, MC: label update to term editor and definition modified accordingly. See https://github.com/information-artifact-ontology/IAO/issues/115.
term editor: PERSON:Daniel Schober
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>

alternative label
type: AnnotationProperty
editor preferred term: alternative label
has curation status: pending final vetting
definition: A label for a class or property that can be used to refer to the class or property instead of the preferred rdfs:label. Alternative labels should be used to indicate community- or context-specific labels, abbreviations, shorthand forms and the like.
term editor: OBO Operations committee
term editor: PERSON:Daniel Schober
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
comment: Consider re-defing to: An alternative name for a class or property which can mean the same thing as the preferred name (semantically equivalent, narrow, broad or related).

definition source
type: AnnotationProperty
editor preferred term: definition source
has curation status: ready for release
definition: Formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007
term editor: PERSON:Daniel Schober
definition source: Discussion on obo-discuss mailing-list, see http://bit.ly/hgm99w
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>

has obsolescence reason
type: AnnotationProperty
editor preferred term: has obsolescence reason
definition: Relates an annotation property to an obsolescence reason. The values of obsolescence reasons come from a list of predefined terms, instances of the class obsolescence reason specification.
term editor: PERSON:Alan Ruttenberg
term editor: PERSON:Melanie Courtot

curator note
type: AnnotationProperty
editor preferred term: curator note
has curation status: ready for release
definition: An administrative note of use for a curator but of no use for a user
term editor: PERSON:Alan Ruttenberg

term tracker item
type: AnnotationProperty
editor preferred term: term tracker item
example of usage: the URI for an OBI Terms ticket at sourceforge, such as https://sourceforge.net/p/obi/obi-terms/772/
has curation status: pending final vetting
definition: An IRI or similar locator for a request or discussion of an ontology term.
term editor: Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg
definition source: Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg
comment: The 'tracker item' can associate a tracker with a specific ontology term.

ontology term requester
type: AnnotationProperty
editor preferred term: ontology term requester
has curation status: pending final vetting
definition: The name of the person, project, or organization that motivated inclusion of an ontology term by requesting its addition.
term editor: Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg
definition source: Person: Jie Zheng, Chris Stoeckert, Alan Ruttenberg
comment: The 'term requester' can credit the person, organization or project who request the ontology term.

is denotator type
type: AnnotationProperty
editor preferred term: is denotator type
definition: Relates an class defined in an ontology, to the type of it's denotator
editor note: In OWL 2 add AnnotationPropertyRange('is denotator type' 'denotator type')
term editor: Alan Ruttenberg

imported from
type: AnnotationProperty
editor preferred term: imported from
has curation status: pending final vetting
definition: For external terms/classes, the ontology from which the term was imported
term editor: PERSON:Alan Ruttenberg
term editor: PERSON:Melanie Courtot
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>

expand expression to
type: AnnotationProperty
editor preferred term: expand expression to
example of usage: ObjectProperty: RO_0002104 Label: has plasma membrane part Annotations: IAO_0000424 "http://purl.obolibrary.org/obo/BFO_0000051 some (http://purl.org/obo/owl/GO#GO_0005886 and http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)"
definition: A macro expansion tag applied to an object property (or possibly a data property) which can be used by a macro-expansion engine to generate more complex expressions from simpler ones
term editor: Chris Mungall

expand assertion to
type: AnnotationProperty
editor preferred term: expand assertion to
example of usage: ObjectProperty: RO??? Label: spatially disjoint from Annotations: expand_assertion_to "DisjointClasses: (http://purl.obolibrary.org/obo/BFO_0000051 some ?X) (http://purl.obolibrary.org/obo/BFO_0000051 some ?Y)"
definition: A macro expansion tag applied to an annotation property which can be expanded into a more detailed axiom.
term editor: Chris Mungall

first order logic expression
type: AnnotationProperty
editor preferred term: first order logic expression
term editor: PERSON:Alan Ruttenberg

antisymmetric property
type: AnnotationProperty
editor preferred term: antisymmetric property
example of usage: part_of antisymmetric property xsd:true
definition: Use boolean value xsd:true to indicate that the property is an antisymmetric property
term editor: Alan Ruttenberg
sub property of: logical characteristic of object property

OBO foundry unique label
type: AnnotationProperty
editor preferred term: OBO foundry unique label
has curation status: pending final vetting
definition: An alternative name for a class or property which is unique across the OBO Foundry.
editor note: The intended usage of that property is as follow: OBO foundry unique labels are automatically generated based on regular expressions provided by each ontology, so that SO could specify unique label = 'sequence ' + [label], etc. , MA could specify 'mouse + [label]' etc. Upon importing terms, ontology developers can choose to use the 'OBO foundry unique label' for an imported term or not. The same applies to tools .
term editor: PERSON:Alan Ruttenberg
term editor: PERSON:Bjoern Peters
term editor: PERSON:Chris Mungall
term editor: PERSON:Melanie Courtot
definition source: GROUP:OBO Foundry <http://obofoundry.org/>

has ID digit count
type: AnnotationProperty
editor preferred term: has ID digit count
example of usage: Ontology: <http://purl.obolibrary.org/obo/ro/idrange/> Annotations: 'has ID prefix': "http://purl.obolibrary.org/obo/RO_" 'has ID digit count' : 7, rdfs:label "RO id policy" 'has ID policy for': "RO"
definition: Relates an ontology used to record id policy to the number of digits in the URI. The URI is: the 'has ID prefix" annotation property value concatenated with an integer in the id range (left padded with "0"s to make this many digits)
term editor: Person:Alan Ruttenberg

has ID range allocated to
type: AnnotationProperty
editor preferred term: has ID range allocated
example of usage: Datatype: idrange:1 Annotations: 'has ID range allocated to': "Chris Mungall" EquivalentTo: xsd:integer[> 2151 , <= 2300]
definition: Relates a datatype that encodes a range of integers to the name of the person or organization who can use those ids constructed in that range to define new terms
term editor: Person:Alan Ruttenberg

has ID policy for
type: AnnotationProperty
editor preferred term: has ID policy for
example of usage: Ontology: <http://purl.obolibrary.org/obo/ro/idrange/> Annotations: 'has ID prefix': "http://purl.obolibrary.org/obo/RO_" 'has ID digit count' : 7, rdfs:label "RO id policy" 'has ID policy for': "RO"
definition: Relating an ontology used to record id policy to the ontology namespace whose policy it manages
term editor: Person:Alan Ruttenberg

has ID prefix
type: AnnotationProperty
editor preferred term: has ID prefix
example of usage: Ontology: <http://purl.obolibrary.org/obo/ro/idrange/> Annotations: 'has ID prefix': "http://purl.obolibrary.org/obo/RO_" 'has ID digit count' : 7, rdfs:label "RO id policy" 'has ID policy for': "RO"
definition: Relates an ontology used to record id policy to a prefix concatenated with an integer in the id range (left padded with "0"s to make this many digits) to construct an ID for a term being created.
term editor: Person:Alan Ruttenberg

elucidation
type: AnnotationProperty
editor preferred term: elucidation
term editor: person:Alan Ruttenberg
definition source: Person:Barry Smith
elucidation: Primitive terms in a highest-level ontology such as BFO are terms which are so basic to our understanding of reality that there is no way of defining them in a non-circular fashion. For these, therefore, we can provide only elucidations, supplemented by examples and by axioms

has associated axiom(nl)
type: AnnotationProperty
editor preferred term: has associated axiom(nl)
term editor: Person:Alan Ruttenberg
definition source: Person:Alan Ruttenberg
elucidation: An axiom associated with a term expressed using natural language

has associated axiom(fol)
type: AnnotationProperty
editor preferred term: has associated axiom(fol)
term editor: Person:Alan Ruttenberg
definition source: Person:Alan Ruttenberg
elucidation: An axiom expressed in first order logic using CLIF syntax

is allocated id range
type: AnnotationProperty
editor preferred term: is allocated id range
definition: Relates an ontology IRI to an (inclusive) range of IRIs in an OBO name space. The range is give as, e.g. "IAO_0020000-IAO_0020999"
term editor: PERSON:Alan Ruttenberg
comment: Add as annotation triples in the granting ontology

has ontology root term
type: AnnotationProperty
editor preferred term: has ontology root term
definition: Ontology annotation property. Relates an ontology to a term that is a designated root term of the ontology. Display tools like OLS can use terms annotated with this property as the starting point for rendering the ontology class hierarchy. There can be more than one root.
term editor: Nicolas Matentzoglu

may be identical to
type: AnnotationProperty
editor preferred term: may be identical to
definition: A annotation relationship between two terms in an ontology that may refer to the same (natural) type but where more evidence is required before terms are merged.
term editor: David Osumi-Sutherland
term tracker item: #40
ontology term requester: VFB
comment: Edges asserting this should be annotated with to record evidence supporting the assertion and its provenance.

scheduled for obsoletion on or after
type: AnnotationProperty
editor preferred term: scheduled for obsoletion on or after
definition: Used when the class or object is scheduled for obsoletion/deprecation on or after a particular date.
term editor: Chris Mungall, Jie Zheng
term tracker item: https://github.com/geneontology/go-ontology/issues/15532
term tracker item: https://github.com/information-artifact-ontology/ontology-metadata/issues/32
ontology term requester: GO ontology
range: dateTime

has axiom label
type: AnnotationProperty
editor preferred term: has axiom id
term editor: Person:Alan Ruttenberg
definition source: Person:Alan Ruttenberg
elucidation: A URI that is intended to be unique label for an axiom used for tracking change to the ontology. For an axiom expressed in different languages, each expression is given the same URI

term replaced by
type: AnnotationProperty
editor preferred term: term replaced by
has curation status: pending final vetting
definition: Use on obsolete terms, relating the term to another term that can be used as a substitute
term editor: Person:Alan Ruttenberg
definition source: Person:Alan Ruttenberg
comment: Add as annotation triples in the granting ontology

logical characteristic of object property
type: AnnotationProperty
definition: This is an annotation used on an object property to indicate a logical characterstic beyond what is possible in OWL.
definition source: OBO Operations call
created by: http://orcid.org/0000-0001-5208-3432

defined by construct
type: AnnotationProperty
example of usage: 'part disjoint with' 'defined by construct' """ PREFIX owl: <http://www.w3.org/2002/07/owl#> PREFIX : <http://example.org/ CONSTRUCT { [ a owl:Restriction ; owl:onProperty :part_of ; owl:someValuesFrom ?a ; owl:disjointWith [ a owl:Restriction ; owl:onProperty :part_of ; owl:someValuesFrom ?b ] ] } WHERE { ?a :part_disjoint_with ?b . }
definition: Links an annotation property to a SPARQL CONSTRUCT query which is meant to provide semantics for a shortcut relation.
term tracker item: https://github.com/ontodev/robot/issues/963
contributor: https://orcid.org/0000-0002-7356-1779
contributor: https://orcid.org/0000-0002-8688-6599

abbreviation
type: AnnotationProperty
example of usage: CHEBI:26523 (reactive oxygen species) has an exact synonym (ROS), which is of type OMO:0003000 (abbreviation)
definition: A synonym type for describing abbreviations or initalisms
term tracker item: https://github.com/information-artifact-ontology/ontology-metadata/issues/122
contributor: https://orcid.org/0000-0003-4423-4370
created: 2023-03-03
sub property of: SynonymType

ambiguous synonym
type: AnnotationProperty
definition: A synonym type for describing ambiguous synonyms
term tracker item: https://github.com/information-artifact-ontology/ontology-metadata/issues/122
contributor: https://orcid.org/0000-0003-4423-4370
created: 2023-03-03
sub property of: SynonymType

dubious synonym
type: AnnotationProperty
definition: A synonym type for describing dubious synonyms
term tracker item: https://github.com/information-artifact-ontology/ontology-metadata/issues/122
contributor: https://orcid.org/0000-0003-4423-4370
created: 2023-03-03
sub property of: SynonymType

layperson synonym
type: AnnotationProperty
example of usage: EFO:0006346 (severe cutaneous adverse reaction) has an exact synonym (scar), which is of the type OMO:0003003 (layperson synonym)
definition: A synonym type for describing layperson or colloquial synonyms
term tracker item: https://github.com/information-artifact-ontology/ontology-metadata/issues/122
contributor: https://orcid.org/0000-0003-4423-4370
created: 2023-03-03
sub property of: SynonymType

plural form
type: AnnotationProperty
example of usage: CHEBI:23367 (molecular entity) has an exact synonym (molecular entities), which is of the type OMO:0003004 (plural form)
definition: A synonym type for describing pluralization synonyms
term tracker item: https://github.com/information-artifact-ontology/ontology-metadata/issues/122
contributor: https://orcid.org/0000-0003-4423-4370
created: 2023-03-03
sub property of: SynonymType

UK spelling synonym
type: AnnotationProperty
example of usage: CHEBI:16189 (sulfate) has an exact synonym (sulphate), which is of the type OMO:0003005 (UK spelling synonym)
definition: A synonym type for describing UK spelling variants
term tracker item: https://github.com/information-artifact-ontology/ontology-metadata/issues/122
contributor: https://orcid.org/0000-0003-4423-4370
created: 2023-03-03
sub property of: SynonymType

misspelling
type: AnnotationProperty
definition: A synonym type for common misspellings
term tracker item: https://github.com/information-artifact-ontology/ontology-metadata/issues/132
contributor: https://orcid.org/0000-0003-4423-4370
created: 2023-03-03
sub property of: SynonymType

misnomer
type: AnnotationProperty
definition: A synonym type for misnomers, i.e., a synonym that is not technically correct but is commonly used anyway
term tracker item: https://github.com/information-artifact-ontology/ontology-metadata/issues/133
contributor: https://orcid.org/0000-0003-4423-4370
created: 2023-03-03
sub property of: SynonymType

temporal interpretation
type: AnnotationProperty
definition: An assertion that holds between an OWL Object Property and a temporal interpretation that elucidates how OWL Class Axioms that use this property are to be interpreted in a temporal context.

logical macro assertion
type: AnnotationProperty
definition: An assertion that involves at least one OWL object that is intended to be expanded into one or more logical axioms. The logical expansion can yield axioms expressed using any formal logical system, including, but not limited to OWL2-DL.

logical macro assertion on a property
type: AnnotationProperty
definition: A logical macro assertion whose domain is an IRI for a property

logical macro assertion on an object property
type: AnnotationProperty
definition: Used to annotate object properties to describe a logical meta-property or characteristic of the object property.

has broad synonym
type: AnnotationProperty
definition: An alternative label for a class or property which has a more general meaning than the preferred name/primary label.
term editor: http://orcid.org/0000-0001-5208-3432
term tracker item: https://github.com/information-artifact-ontology/ontology-metadata/issues/18
sub property of: alternative label

has exact synonym
type: AnnotationProperty
definition: An alternative label for a class or property which has the exact same meaning than the preferred name/primary label.
term editor: http://orcid.org/0000-0001-5208-3432
term tracker item: https://github.com/information-artifact-ontology/ontology-metadata/issues/20
sub property of: alternative label

has narrow synonym
type: AnnotationProperty
definition: An alternative label for a class or property which has a more specific meaning than the preferred name/primary label.
term editor: http://orcid.org/0000-0001-5208-3432
term tracker item: https://github.com/information-artifact-ontology/ontology-metadata/issues/19
sub property of: alternative label

has related synonym
type: AnnotationProperty
definition: An alternative label for a class or property that has been used synonymously with the primary term name, but the usage is not strictly correct.
term editor: http://orcid.org/0000-0001-5208-3432
term tracker item: https://github.com/information-artifact-ontology/ontology-metadata/issues/21
sub property of: alternative label

part of
type: ObjectProperty
inverse of: has part
type: TransitiveProperty
editor preferred term: is part of
example of usage: my brain is part of my body (continuant parthood, two material entities)
example of usage: my stomach cavity is part of my stomach (continuant parthood, immaterial entity is part of material entity)
example of usage: this day is part of this year (occurrent parthood)
definition: a core relation that holds between a part and its whole
editor note: Everything is part of itself. Any part of any part of a thing is itself part of that thing. Two distinct things cannot be part of each other.
editor note: Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
editor note: Parthood requires the part and the whole to have compatible classes: only an occurrent can be part of an occurrent; only a process can be part of a process; only a continuant can be part of a continuant; only an independent continuant can be part of an independent continuant; only an immaterial entity can be part of an immaterial entity; only a specifically dependent continuant can be part of a specifically dependent continuant; only a generically dependent continuant can be part of a generically dependent continuant. (This list is not exhaustive.) A continuant cannot be part of an occurrent: use 'participates in'. An occurrent cannot be part of a continuant: use 'has participant'. A material entity cannot be part of an immaterial entity: use 'has location'. A specifically dependent continuant cannot be part of an independent continuant: use 'inheres in'. An independent continuant cannot be part of a specifically dependent continuant: use 'bearer of'.
alternative label: part_of
temporal interpretation: RO_0001901

has part
type: ObjectProperty
type: TransitiveProperty
editor preferred term: has part
example of usage: my body has part my brain (continuant parthood, two material entities)
example of usage: my stomach has part my stomach cavity (continuant parthood, material entity has part immaterial entity)
example of usage: this year has part this day (occurrent parthood)
definition: a core relation that holds between a whole and its part
editor note: Everything has itself as a part. Any part of any part of a thing is itself part of that thing. Two distinct things cannot have each other as a part.
editor note: Occurrents are not subject to change and so parthood between occurrents holds for all the times that the part exists. Many continuants are subject to change, so parthood between continuants will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
editor note: Parthood requires the part and the whole to have compatible classes: only an occurrent have an occurrent as part; only a process can have a process as part; only a continuant can have a continuant as part; only an independent continuant can have an independent continuant as part; only a specifically dependent continuant can have a specifically dependent continuant as part; only a generically dependent continuant can have a generically dependent continuant as part. (This list is not exhaustive.) A continuant cannot have an occurrent as part: use 'participates in'. An occurrent cannot have a continuant as part: use 'has participant'. An immaterial entity cannot have a material entity as part: use 'location of'. An independent continuant cannot have a specifically dependent continuant as part: use 'bearer of'. A specifically dependent continuant cannot have an independent continuant as part: use 'inheres in'.
alternative label: has_part
temporal interpretation: RO_0001901

realized in
type: ObjectProperty
inverse of: realizes
domain: realizable entity
range: process
editor preferred term: realized in
example of usage: this disease is realized in this disease course
example of usage: this fragility is realized in this shattering
example of usage: this investigator role is realized in this investigation
alternative label: is realized by
alternative label: realized_in
elucidation: [copied from inverse property 'realizes'] to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])
comment: Paraphrase of elucidation: a relation between a realizable entity and a process, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process

realizes
type: ObjectProperty
domain: process
range: realizable entity
editor preferred term: realizes
example of usage: this disease course realizes this disease
example of usage: this investigation realizes this investigator role
example of usage: this shattering realizes this fragility
elucidation: to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])
comment: Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process

occurs in
type: ObjectProperty
inverse of: contains process
domain: occurrent
range: independent continuant
property chain axiom: part of
editor preferred term: occurs in
definition: b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t
alternative label: occurs_in
alternative label: unfolds in
alternative label: unfolds_in
comment: Paraphrase of definition: a relation between a process and an independent continuant, in which the process takes place entirely within the independent continuant

contains process
type: ObjectProperty
editor preferred term: site of
definition: [copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t
comment: Paraphrase of definition: a relation between an independent continuant and a process, in which the process takes place entirely within the independent continuant

obsolete_has vector
type: ObjectProperty
definition: A relation between an organism and an organism that has vector role.
term replaced by: has vector
deprecated: true

obsolete_has host
type: ObjectProperty
definition: A relation between an organism and an organism that has host role.
term replaced by: has host
deprecated: true

characteristic of
type: ObjectProperty
inverse of: has characteristic
type: FunctionalProperty
editor preferred term: inheres in
example of usage: this fragility is a characteristic of this vase
example of usage: this red color is a characteristic of this apple
definition: a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence.
alternative label: inheres_in
temporal interpretation: RO_0001901
comment: Note that this relation was previously called "inheres in", but was changed to be called "characteristic of" because BFO2 uses "inheres in" in a more restricted fashion. This relation differs from BFO2:inheres_in in two respects: (1) it does not impose a range constraint, and thus it allows qualities of processes, as well as of information entities, whereas BFO2 restricts inheres_in to only apply to independent continuants (2) it is declared functional, i.e. something can only be a characteristic of one thing.

has characteristic
type: ObjectProperty
type: InverseFunctionalProperty
range: specifically dependent continuant
editor preferred term: bearer of
example of usage: this apple is bearer of this red color
example of usage: this vase is bearer of this fragility
definition: Inverse of characteristic_of
editor note: A bearer can have many dependents, and its dependents can exist for different periods of time, but none of its dependents can exist when the bearer does not exist.
alternative label: bearer_of
alternative label: is bearer of
temporal interpretation: RO_0001901

participates in
type: ObjectProperty
inverse of: has participant
domain: continuant
range: occurrent
editor preferred term: participates in
example of usage: this blood clot participates in this blood coagulation
example of usage: this input material (or this output material) participates in this process
example of usage: this investigator participates in this investigation
definition: a relation between a continuant and a process, in which the continuant is somehow involved in the process
alternative label: participates_in

has participant
type: ObjectProperty
domain: occurrent
range: continuant
editor preferred term: has participant
example of usage: this blood coagulation has participant this blood clot
example of usage: this investigation has participant this investigator
example of usage: this process has participant this input material (or this output material)
definition: a relation between a process and a continuant, in which the continuant is somehow involved in the process
editor note: Has_participant is a primitive instance-level relation between a process, a continuant, and a time at which the continuant participates in some way in the process. The relation obtains, for example, when this particular process of oxygen exchange across this particular alveolar membrane has_participant this particular sample of hemoglobin at this particular time.
alternative label: has_participant
source: http://www.obofoundry.org/ro/#OBO_REL:has_participant

is concretized as
type: ObjectProperty
inverse of: concretizes
domain: generically dependent continuant
range: specifically dependent continuant
example of usage: A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The journal article (a generically dependent continuant) is concretized as the quality (a specifically dependent continuant), and both depend on that copy of the printed journal (an independent continuant).
example of usage: An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process).
definition: A relationship between a generically dependent continuant and a specifically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants.

concretizes
type: ObjectProperty
domain: specifically dependent continuant
range: generically dependent continuant
example of usage: A journal article is an information artifact that inheres in some number of printed journals. For each copy of the printed journal there is some quality that carries the journal article, such as a pattern of ink. The quality (a specifically dependent continuant) concretizes the journal article (a generically dependent continuant), and both depend on that copy of the printed journal (an independent continuant).
example of usage: An investigator reads a protocol and forms a plan to carry out an assay. The plan is a realizable entity (a specifically dependent continuant) that concretizes the protocol (a generically dependent continuant), and both depend on the investigator (an independent continuant). The plan is then realized by the assay (a process).
definition: A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant.

function of
type: ObjectProperty
sub property of: characteristic of
inverse of: has function
domain: function
example of usage: this catalysis function is a function of this enzyme
definition: a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence
editor note: A function inheres in its bearer at all times for which the function exists, however the function need not be realized at all the times that the function exists.
alternative label: function_of
alternative label: is function of
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.

quality of
type: ObjectProperty
sub property of: characteristic of
inverse of: has quality
example of usage: this red color is a quality of this apple
definition: a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence
editor note: A quality inheres in its bearer at all times for which the quality exists.
alternative label: is quality of
alternative label: quality_of
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.

role of
type: ObjectProperty
sub property of: characteristic of
inverse of: has role
example of usage: this investigator role is a role of this person
definition: a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence
editor note: A role inheres in its bearer at all times for which the role exists, however the role need not be realized at all the times that the role exists.
alternative label: is role of
alternative label: role_of
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.

has function
type: ObjectProperty
sub property of: has characteristic
domain: independent continuant
range: function
example of usage: this enzyme has function this catalysis function (more colloquially: this enzyme has this catalysis function)
definition: a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence
editor note: A bearer can have many functions, and its functions can exist for different periods of time, but none of its functions can exist when the bearer does not exist. A function need not be realized at all the times that the function exists.
alternative label: has_function

has quality
type: ObjectProperty
sub property of: has characteristic
range: quality
example of usage: this apple has quality this red color
definition: a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence
editor note: A bearer can have many qualities, and its qualities can exist for different periods of time, but none of its qualities can exist when the bearer does not exist.
alternative label: has_quality

has role
type: ObjectProperty
sub property of: has characteristic
domain: independent continuant
range: role
example of usage: this person has role this investigator role (more colloquially: this person has this role of investigator)
definition: a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence
editor note: A bearer can have many roles, and its roles can exist for different periods of time, but none of its roles can exist when the bearer does not exist. A role need not be realized at all the times that the role exists.
alternative label: has_role

has disposition
type: ObjectProperty
sub property of: has characteristic
inverse of: disposition of
domain: independent continuant
range: disposition
definition: a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence

disposition of
type: ObjectProperty
sub property of: characteristic of
comment: This relation is modeled after the BFO relation of the same name which was in BFO2, but is used in a more restricted sense - specifically, we model this relation as functional (inherited from characteristic-of). Note that this relation is now removed from BFO2020.

derives from
type: ObjectProperty
inverse of: derives into
example of usage: this cell derives from this parent cell (cell division)
example of usage: this nucleus derives from this parent nucleus (nuclear division)
has curation status: pending final vetting
definition: a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity
editor note: This is a very general relation. More specific relations are preferred when applicable, such as 'directly develops from'.
alternative label: derives_from

derives into
type: ObjectProperty
example of usage: this parent cell derives into this cell (cell division)
example of usage: this parent nucleus derives into this nucleus (nuclear division)
has curation status: pending final vetting
definition: a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity
editor note: This is a very general relation. More specific relations are preferred when applicable, such as 'directly develops into'. To avoid making statements about a future that may not come to pass, it is often better to use the backward-looking 'derives from' rather than the forward-looking 'derives into'.
alternative label: derives_into

location of
type: ObjectProperty
inverse of: located in
type: TransitiveProperty
editor preferred term: is location of
example of usage: my head is the location of my brain
example of usage: this cage is the location of this rat
definition: a relation between two independent continuants, the location and the target, in which the target is entirely within the location
editor note: Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
alternative label: location_of
temporal interpretation: RO_0001901

located in
type: ObjectProperty
type: TransitiveProperty
domain: independent continuant
domain: Class
  intersection of: independent continuant
  intersection of: Class
    complement of: spatial region
range: independent continuant
range: Class
  intersection of: independent continuant
  intersection of: Class
    complement of: spatial region
editor preferred term: located in
example of usage: my brain is located in my head
example of usage: this rat is located in this cage
definition: a relation between two independent continuants, the target and the location, in which the target is entirely within the location
editor note: Location as a relation between instances: The primitive instance-level relation c located_in r at t reflects the fact that each continuant is at any given time associated with exactly one spatial region, namely its exact location. Following we can use this relation to define a further instance-level location relation - not between a continuant and the region which it exactly occupies, but rather between one continuant and another. c is located in c1, in this sense, whenever the spatial region occupied by c is part_of the spatial region occupied by c1. Note that this relation comprehends both the relation of exact location between one continuant and another which obtains when r and r1 are identical (for example, when a portion of fluid exactly fills a cavity), as well as those sorts of inexact location relations which obtain, for example, between brain and head or between ovum and uterus
editor note: Most location relations will only hold at certain times, but this is difficult to specify in OWL. See http://purl.obolibrary.org/obo/ro/docs/temporal-semantics/
alternative label: located_in
temporal interpretation: RO_0001901
source: http://www.obofoundry.org/ro/#OBO_REL:located_in

Axiom
annotated source: located in
annotated property: range
annotated target: independent continuant
editor note: This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation.

Axiom
annotated source: located in
annotated property: domain
annotated target: independent continuant
editor note: This is redundant with the more specific 'independent and not spatial region' constraint. We leave in the redundant axiom for use with reasoners that do not use negation.

2D boundary of
type: ObjectProperty
inverse of: has 2D boundary
example of usage: the surface of my skin is a 2D boundary of my body
definition: a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity
editor note: A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts.
editor note: Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape.
alternative label: 2D_boundary_of
alternative label: boundary of
alternative label: is 2D boundary of
alternative label: is boundary of
temporal interpretation: RO_0001901

has 2D boundary
type: ObjectProperty
domain: material entity
range: immaterial entity
example of usage: my body has 2D boundary the surface of my skin
definition: a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity
editor note: A 2D boundary may have holes and gaps, but it must be a single connected entity, not an aggregate of several disconnected parts.
editor note: Although the boundary is two-dimensional, it exists in three-dimensional space and thus has a 3D shape.
alternative label: has boundary
alternative label: has_2D_boundary
temporal interpretation: RO_0001901

in taxon
type: ObjectProperty
sub property of: evolutionarily related to
definition: x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed.
imported from: ro.owl

evolutionarily related to
type: ObjectProperty
definition: A relationship that holds via some environmental process
imported from: ro.owl

ecologically related to
type: ObjectProperty
definition: A relationship that is mediated in some way by the environment or environmental feature (ENVO:00002297)
imported from: ro.owl

member of
type: ObjectProperty
sub property of: part of
inverse of: has member
example of usage: An organism that is a member of a population of organisms
definition: is member of is a mereological relation between a item and a collection.
alternative label: is member of
alternative label: member part of
definition source: SIO
temporal interpretation: RO_0001901

has member
type: ObjectProperty
sub property of: has part
type: IrreflexiveProperty
definition: has member is a mereological relation between a collection and an item.
definition source: SIO
temporal interpretation: RO_0001901

has host
type: ObjectProperty
sub property of: ecologically related to
definition: X 'has host' y if and only if: x is an organism, y is an organism, and x can live on the surface of or within the body of y
imported from: ro.owl

has vector
type: ObjectProperty
sub property of: ecologically related to
imported from: ro.owl

DEPRECATED inheres in
type: ObjectProperty
comment: DEPRECATED This relation is similar to but different in important respects to the characteristic-of relation. See comments on that relation for more information.
deprecated: true

DEPRECATED bearer of
type: ObjectProperty
deprecated: true

entity
type: Class
subclass of: Thing
BFO OWL specification label: entity
BFO CLIF specification label: Entity
example of usage: Julius Caesar
example of usage: Verdi’s Requiem
example of usage: the Second World War
example of usage: your body mass index
editor note: BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81
editor note: Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf
elucidation: An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])

Axiom
annotated source: entity
annotated property: editor note
annotated target: Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000004
comment: per discussion with Barry Smith

Axiom
annotated source: entity
annotated property: elucidation
annotated target: An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/001-001

continuant
type: Class
subclass of: entity
disjoint with: occurrent
disjoint with: Restriction
  on property: part of
  some values from: occurrent
BFO OWL specification label: continuant
BFO CLIF specification label: Continuant
definition: An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.
editor note: BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240
editor note: Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants
elucidation: A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])
has associated axiom(nl): if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])
has associated axiom(nl): if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])
has associated axiom(nl): if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])
has associated axiom(fol): (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002]
has associated axiom(fol): (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001]
has associated axiom(fol): (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002]
has associated axiom(fol): (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002]

Axiom
annotated source: continuant
annotated property: editor note
annotated target: Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000007

Axiom
annotated source: continuant
annotated property: elucidation
annotated target: A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/008-002

Axiom
annotated source: continuant
annotated property: has associated axiom(nl)
annotated target: if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/126-001

Axiom
annotated source: continuant
annotated property: has associated axiom(nl)
annotated target: if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/009-002

Axiom
annotated source: continuant
annotated property: has associated axiom(nl)
annotated target: if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/011-002

Axiom
annotated source: continuant
annotated property: has associated axiom(fol)
annotated target: (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/009-002

Axiom
annotated source: continuant
annotated property: has associated axiom(fol)
annotated target: (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/126-001

Axiom
annotated source: continuant
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/008-002

Axiom
annotated source: continuant
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/011-002

occurrent
type: Class
subclass of: entity
disjoint with: Restriction
  on property: part of
  some values from: continuant
BFO OWL specification label: occurrent
BFO CLIF specification label: Occurrent
definition: An entity that has temporal parts and that happens, unfolds or develops through time.
editor note: BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region
editor note: BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players.
editor note: Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process.
editor note: Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame.
elucidation: An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])
has associated axiom(nl): Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])
has associated axiom(nl): b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])
has associated axiom(fol): (forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001]
has associated axiom(fol): (forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001]

Axiom
annotated source: occurrent
annotated property: editor note
annotated target: Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process.
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000006
comment: per discussion with Barry Smith

Axiom
annotated source: occurrent
annotated property: editor note
annotated target: Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame.
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000012

Axiom
annotated source: occurrent
annotated property: elucidation
annotated target: An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/077-002

Axiom
annotated source: occurrent
annotated property: has associated axiom(nl)
annotated target: Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/108-001

Axiom
annotated source: occurrent
annotated property: has associated axiom(nl)
annotated target: b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/079-001

Axiom
annotated source: occurrent
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/108-001

Axiom
annotated source: occurrent
annotated property: has associated axiom(fol)
annotated target: (forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/079-001

independent continuant
type: Class
subclass of: continuant
disjoint with: specifically dependent continuant
disjoint with: generically dependent continuant
BFO OWL specification label: ic
BFO CLIF specification label: IndependentContinuant
example of usage: a chair
example of usage: a heart
example of usage: a leg
example of usage: a molecule
example of usage: a spatial region
example of usage: an atom
example of usage: an orchestra.
example of usage: an organism
example of usage: the bottom right portion of a human torso
example of usage: the interior of your mouth
definition: A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.
definition: b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])
has associated axiom(nl): For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])
has associated axiom(nl): For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])
has associated axiom(fol): (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001]
has associated axiom(fol): (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002]
has associated axiom(fol): (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002]

Axiom
annotated source: independent continuant
annotated property: definition
annotated target: b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/017-002

Axiom
annotated source: independent continuant
annotated property: has associated axiom(nl)
annotated target: For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/134-001

Axiom
annotated source: independent continuant
annotated property: has associated axiom(nl)
annotated target: For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/018-002

Axiom
annotated source: independent continuant
annotated property: has associated axiom(fol)
annotated target: (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/134-001

Axiom
annotated source: independent continuant
annotated property: has associated axiom(fol)
annotated target: (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/018-002

Axiom
annotated source: independent continuant
annotated property: has associated axiom(fol)
annotated target: (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/017-002

spatial region
type: Class
subclass of: immaterial entity
disjoint with: site
disjoint with: continuant fiat boundary
BFO OWL specification label: s-region
BFO CLIF specification label: SpatialRegion
editor note: BFO 2 Reference: Spatial regions do not participate in processes.
editor note: Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional.
elucidation: A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001])
has associated axiom(nl): All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001])
has associated axiom(fol): (forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001]
has associated axiom(fol): (forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001]

Axiom
annotated source: spatial region
annotated property: editor note
annotated target: Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional.
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000002
comment: per discussion with Barry Smith

Axiom
annotated source: spatial region
annotated property: elucidation
annotated target: A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/035-001

Axiom
annotated source: spatial region
annotated property: has associated axiom(nl)
annotated target: All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/036-001

Axiom
annotated source: spatial region
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/036-001

Axiom
annotated source: spatial region
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/035-001

temporal region
type: Class
subclass of: occurrent
disjoint with: spatiotemporal region
disjoint with: process
disjoint with: process boundary
BFO OWL specification label: t-region
BFO CLIF specification label: TemporalRegion
editor note: Temporal region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn't overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional
elucidation: A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001])
has associated axiom(nl): All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001])
has associated axiom(nl): Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002])
has associated axiom(fol): (forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002]
has associated axiom(fol): (forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001]
has associated axiom(fol): (forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001]

Axiom
annotated source: temporal region
annotated property: editor note
annotated target: Temporal region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn't overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000003
comment: per discussion with Barry Smith

Axiom
annotated source: temporal region
annotated property: elucidation
annotated target: A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/100-001

Axiom
annotated source: temporal region
annotated property: has associated axiom(nl)
annotated target: All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/101-001

Axiom
annotated source: temporal region
annotated property: has associated axiom(nl)
annotated target: Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/119-002

Axiom
annotated source: temporal region
annotated property: has associated axiom(fol)
annotated target: (forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/119-002

Axiom
annotated source: temporal region
annotated property: has associated axiom(fol)
annotated target: (forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/101-001

Axiom
annotated source: temporal region
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/100-001

two-dimensional spatial region
type: Class
subclass of: spatial region
disjoint with: three-dimensional spatial region
BFO OWL specification label: 2d-s-region
BFO CLIF specification label: TwoDimensionalSpatialRegion
example of usage: an infinitely thin plane in space.
example of usage: the surface of a sphere-shaped part of space
elucidation: A two-dimensional spatial region is a spatial region that is of two dimensions. (axiom label in BFO2 Reference: [039-001])
has associated axiom(fol): (forall (x) (if (TwoDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [039-001]

Axiom
annotated source: two-dimensional spatial region
annotated property: elucidation
annotated target: A two-dimensional spatial region is a spatial region that is of two dimensions. (axiom label in BFO2 Reference: [039-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/039-001

Axiom
annotated source: two-dimensional spatial region
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (TwoDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [039-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/039-001

spatiotemporal region
type: Class
subclass of: occurrent
BFO OWL specification label: st-region
BFO CLIF specification label: SpatiotemporalRegion
example of usage: the spatiotemporal region occupied by a human life
example of usage: the spatiotemporal region occupied by a process of cellular meiosis.
example of usage: the spatiotemporal region occupied by the development of a cancer tumor
elucidation: A spatiotemporal region is an occurrent entity that is part of spacetime. (axiom label in BFO2 Reference: [095-001])
has associated axiom(nl): All parts of spatiotemporal regions are spatiotemporal regions. (axiom label in BFO2 Reference: [096-001])
has associated axiom(nl): Each spatiotemporal region at any time t projects_onto some spatial region at t. (axiom label in BFO2 Reference: [099-001])
has associated axiom(nl): Each spatiotemporal region projects_onto some temporal region. (axiom label in BFO2 Reference: [098-001])
has associated axiom(nl): Every spatiotemporal region occupies_spatiotemporal_region itself.
has associated axiom(nl): Every spatiotemporal region s is such that s occupies_spatiotemporal_region s. (axiom label in BFO2 Reference: [107-002])
has associated axiom(fol): (forall (r) (if (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion r r))) // axiom label in BFO2 CLIF: [107-002]
has associated axiom(fol): (forall (x t) (if (SpatioTemporalRegion x) (exists (y) (and (SpatialRegion y) (spatiallyProjectsOntoAt x y t))))) // axiom label in BFO2 CLIF: [099-001]
has associated axiom(fol): (forall (x y) (if (and (SpatioTemporalRegion x) (occurrentPartOf y x)) (SpatioTemporalRegion y))) // axiom label in BFO2 CLIF: [096-001]
has associated axiom(fol): (forall (x) (if (SpatioTemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [095-001]
has associated axiom(fol): (forall (x) (if (SpatioTemporalRegion x) (exists (y) (and (TemporalRegion y) (temporallyProjectsOnto x y))))) // axiom label in BFO2 CLIF: [098-001]

Axiom
annotated source: spatiotemporal region
annotated property: elucidation
annotated target: A spatiotemporal region is an occurrent entity that is part of spacetime. (axiom label in BFO2 Reference: [095-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/095-001

Axiom
annotated source: spatiotemporal region
annotated property: has associated axiom(nl)
annotated target: All parts of spatiotemporal regions are spatiotemporal regions. (axiom label in BFO2 Reference: [096-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/096-001

Axiom
annotated source: spatiotemporal region
annotated property: has associated axiom(nl)
annotated target: Each spatiotemporal region at any time t projects_onto some spatial region at t. (axiom label in BFO2 Reference: [099-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/099-001

Axiom
annotated source: spatiotemporal region
annotated property: has associated axiom(nl)
annotated target: Each spatiotemporal region projects_onto some temporal region. (axiom label in BFO2 Reference: [098-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/098-001

Axiom
annotated source: spatiotemporal region
annotated property: has associated axiom(nl)
annotated target: Every spatiotemporal region s is such that s occupies_spatiotemporal_region s. (axiom label in BFO2 Reference: [107-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/107-002

Axiom
annotated source: spatiotemporal region
annotated property: has associated axiom(fol)
annotated target: (forall (r) (if (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion r r))) // axiom label in BFO2 CLIF: [107-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/107-002

Axiom
annotated source: spatiotemporal region
annotated property: has associated axiom(fol)
annotated target: (forall (x t) (if (SpatioTemporalRegion x) (exists (y) (and (SpatialRegion y) (spatiallyProjectsOntoAt x y t))))) // axiom label in BFO2 CLIF: [099-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/099-001

Axiom
annotated source: spatiotemporal region
annotated property: has associated axiom(fol)
annotated target: (forall (x y) (if (and (SpatioTemporalRegion x) (occurrentPartOf y x)) (SpatioTemporalRegion y))) // axiom label in BFO2 CLIF: [096-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/096-001

Axiom
annotated source: spatiotemporal region
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (SpatioTemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [095-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/095-001

Axiom
annotated source: spatiotemporal region
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (SpatioTemporalRegion x) (exists (y) (and (TemporalRegion y) (temporallyProjectsOnto x y))))) // axiom label in BFO2 CLIF: [098-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/098-001

process
type: Class
subclass of: occurrent
BFO OWL specification label: process
BFO CLIF specification label: Process
example of usage: a process of cell-division, \ a beating of the heart
example of usage: a process of meiosis
example of usage: a process of sleeping
example of usage: the course of a disease
example of usage: the flight of a bird
example of usage: the life of an organism
example of usage: your process of aging.
definition: An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.
definition: p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])
editor note: BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war)
has associated axiom(fol): (iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003]

Axiom
annotated source: process
annotated property: definition
annotated target: p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/083-003

Axiom
annotated source: process
annotated property: has associated axiom(fol)
annotated target: (iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/083-003

disposition
type: Class
subclass of: realizable entity
disjoint with: role
BFO OWL specification label: disposition
BFO CLIF specification label: Disposition
example of usage: an atom of element X has the disposition to decay to an atom of element Y
example of usage: certain people have a predisposition to colon cancer
example of usage: children are innately disposed to categorize objects in certain ways.
example of usage: the cell wall is disposed to filter chemicals in endocytosis and exocytosis
editor note: BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type.
elucidation: b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])
has associated axiom(nl): If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])
has associated axiom(fol): (forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002]
has associated axiom(fol): (forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002]

Axiom
annotated source: disposition
annotated property: elucidation
annotated target: b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/062-002

Axiom
annotated source: disposition
annotated property: has associated axiom(nl)
annotated target: If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/063-002

Axiom
annotated source: disposition
annotated property: has associated axiom(fol)
annotated target: (forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/063-002

Axiom
annotated source: disposition
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/062-002

realizable entity
type: Class
subclass of: specifically dependent continuant
disjoint with: quality
BFO OWL specification label: realizable
BFO CLIF specification label: RealizableEntity
example of usage: the disposition of this piece of metal to conduct electricity.
example of usage: the disposition of your blood to coagulate
example of usage: the function of your reproductive organs
example of usage: the role of being a doctor
example of usage: the role of this boundary to delineate where Utah and Colorado meet
definition: A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances.
elucidation: To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])
has associated axiom(nl): All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])
has associated axiom(fol): (forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002]
has associated axiom(fol): (forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002]

Axiom
annotated source: realizable entity
annotated property: elucidation
annotated target: To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/058-002

Axiom
annotated source: realizable entity
annotated property: has associated axiom(nl)
annotated target: All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/060-002

Axiom
annotated source: realizable entity
annotated property: has associated axiom(fol)
annotated target: (forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/060-002

Axiom
annotated source: realizable entity
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/058-002

zero-dimensional spatial region
type: Class
subclass of: spatial region
disjoint with: three-dimensional spatial region
BFO OWL specification label: 0d-s-region
BFO CLIF specification label: ZeroDimensionalSpatialRegion
elucidation: A zero-dimensional spatial region is a point in space. (axiom label in BFO2 Reference: [037-001])
has associated axiom(fol): (forall (x) (if (ZeroDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [037-001]

Axiom
annotated source: zero-dimensional spatial region
annotated property: elucidation
annotated target: A zero-dimensional spatial region is a point in space. (axiom label in BFO2 Reference: [037-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/037-001

Axiom
annotated source: zero-dimensional spatial region
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (ZeroDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [037-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/037-001

quality
type: Class
subclass of: specifically dependent continuant
BFO OWL specification label: quality
BFO CLIF specification label: Quality
example of usage: the ambient temperature of this portion of air
example of usage: the color of a tomato
example of usage: the length of the circumference of your waist
example of usage: the mass of this piece of gold.
example of usage: the shape of your nose
example of usage: the shape of your nostril
elucidation: a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])
has associated axiom(nl): If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])
has associated axiom(fol): (forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001]
has associated axiom(fol): (forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001]

Axiom
annotated source: quality
annotated property: elucidation
annotated target: a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/055-001

Axiom
annotated source: quality
annotated property: has associated axiom(nl)
annotated target: If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/105-001

Axiom
annotated source: quality
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/055-001

Axiom
annotated source: quality
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/105-001

specifically dependent continuant
type: Class
subclass of: continuant
disjoint with: generically dependent continuant
BFO OWL specification label: sdc
BFO CLIF specification label: SpecificallyDependentContinuant
example of usage: Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key
example of usage: of one-sided specifically dependent continuants: the mass of this tomato
example of usage: of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates.
example of usage: the disposition of this fish to decay
example of usage: the function of this heart: to pump blood
example of usage: the mutual dependence of proton donors and acceptors in chemical reactions [79
example of usage: the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction
example of usage: the pink color of a medium rare piece of grilled filet mignon at its center
example of usage: the role of being a doctor
example of usage: the shape of this hole.
example of usage: the smell of this portion of mozzarella
definition: A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.
definition: b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])
editor note: Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc.
has associated axiom(fol): (iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003]

Axiom
annotated source: specifically dependent continuant
annotated property: definition
annotated target: b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/050-003

Axiom
annotated source: specifically dependent continuant
annotated property: editor note
annotated target: Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc.
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000005
comment: per discussion with Barry Smith

Axiom
annotated source: specifically dependent continuant
annotated property: has associated axiom(fol)
annotated target: (iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/050-003

role
type: Class
subclass of: realizable entity
BFO OWL specification label: role
BFO CLIF specification label: Role
example of usage: John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married.
example of usage: the priest role
example of usage: the role of a boundary to demarcate two neighboring administrative territories
example of usage: the role of a building in serving as a military target
example of usage: the role of a stone in marking a property boundary
example of usage: the role of subject in a clinical trial
example of usage: the student role
definition: A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts.
editor note: BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals – professor, sergeant, nurse – only during certain phases in their lives.
elucidation: b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])
has associated axiom(fol): (forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001]

Axiom
annotated source: role
annotated property: elucidation
annotated target: b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/061-001

Axiom
annotated source: role
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/061-001

fiat object part
type: Class
subclass of: material entity
BFO OWL specification label: fiat-object-part
BFO CLIF specification label: FiatObjectPart
example of usage: or with divisions drawn by cognitive subjects for practical reasons, such as the division of a cake (before slicing) into (what will become) slices (and thus member parts of an object aggregate). However, this does not mean that fiat object parts are dependent for their existence on divisions or delineations effected by cognitive subjects. If, for example, it is correct to conceive geological layers of the Earth as fiat object parts of the Earth, then even though these layers were first delineated in recent times, still existed long before such delineation and what holds of these layers (for example that the oldest layers are also the lowest layers) did not begin to hold because of our acts of delineation.Treatment of material entity in BFOExamples viewed by some as problematic cases for the trichotomy of fiat object part, object, and object aggregate include: a mussel on (and attached to) a rock, a slime mold, a pizza, a cloud, a galaxy, a railway train with engine and multiple carriages, a clonal stand of quaking aspen, a bacterial community (biofilm), a broken femur. Note that, as Aristotle already clearly recognized, such problematic cases – which lie at or near the penumbra of instances defined by the categories in question – need not invalidate these categories. The existence of grey objects does not prove that there are not objects which are black and objects which are white; the existence of mules does not prove that there are not objects which are donkeys and objects which are horses. It does, however, show that the examples in question need to be addressed carefully in order to show how they can be fitted into the proposed scheme, for example by recognizing additional subdivisions [29
example of usage: the FMA:regional parts of an intact human body.
example of usage: the Western hemisphere of the Earth
example of usage: the division of the brain into regions
example of usage: the division of the planet into hemispheres
example of usage: the dorsal and ventral surfaces of the body
example of usage: the upper and lower lobes of the left lung
editor note: BFO 2 Reference: Most examples of fiat object parts are associated with theoretically drawn divisions
elucidation: b is a fiat object part = Def. b is a material entity which is such that for all times t, if b exists at t then there is some object c such that b proper continuant_part of c at t and c is demarcated from the remainder of c by a two-dimensional continuant fiat boundary. (axiom label in BFO2 Reference: [027-004])
has associated axiom(fol): (forall (x) (if (FiatObjectPart x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y) (and (Object y) (properContinuantPartOfAt x y t)))))))) // axiom label in BFO2 CLIF: [027-004]

Axiom
annotated source: fiat object part
annotated property: elucidation
annotated target: b is a fiat object part = Def. b is a material entity which is such that for all times t, if b exists at t then there is some object c such that b proper continuant_part of c at t and c is demarcated from the remainder of c by a two-dimensional continuant fiat boundary. (axiom label in BFO2 Reference: [027-004])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/027-004

Axiom
annotated source: fiat object part
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (FiatObjectPart x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y) (and (Object y) (properContinuantPartOfAt x y t)))))))) // axiom label in BFO2 CLIF: [027-004]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/027-004

one-dimensional spatial region
type: Class
subclass of: spatial region
disjoint with: three-dimensional spatial region
BFO OWL specification label: 1d-s-region
BFO CLIF specification label: OneDimensionalSpatialRegion
example of usage: an edge of a cube-shaped portion of space.
elucidation: A one-dimensional spatial region is a line or aggregate of lines stretching from one point in space to another. (axiom label in BFO2 Reference: [038-001])
has associated axiom(fol): (forall (x) (if (OneDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [038-001]

Axiom
annotated source: one-dimensional spatial region
annotated property: elucidation
annotated target: A one-dimensional spatial region is a line or aggregate of lines stretching from one point in space to another. (axiom label in BFO2 Reference: [038-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/038-001

Axiom
annotated source: one-dimensional spatial region
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (OneDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [038-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/038-001

object aggregate
type: Class
subclass of: material entity
BFO OWL specification label: object-aggregate
BFO CLIF specification label: ObjectAggregate
example of usage: a collection of cells in a blood biobank.
example of usage: a swarm of bees is an aggregate of members who are linked together through natural bonds
example of usage: a symphony orchestra
example of usage: an organization is an aggregate whose member parts have roles of specific types (for example in a jazz band, a chess club, a football team)
example of usage: defined by fiat: the aggregate of members of an organization
example of usage: defined through physical attachment: the aggregate of atoms in a lump of granite
example of usage: defined through physical containment: the aggregate of molecules of carbon dioxide in a sealed container
example of usage: defined via attributive delimitations such as: the patients in this hospital
example of usage: the aggregate of bearings in a constant velocity axle joint
example of usage: the aggregate of blood cells in your body
example of usage: the nitrogen atoms in the atmosphere
example of usage: the restaurants in Palo Alto
example of usage: your collection of Meissen ceramic plates.
editor note: An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects
editor note: BFO 2 Reference: object aggregates may gain and lose parts while remaining numerically identical (one and the same individual) over time. This holds both for aggregates whose membership is determined naturally (the aggregate of cells in your body) and aggregates determined by fiat (a baseball team, a congressional committee).
definition source: ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, 'A Theory of Granular Partitions', in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158.
elucidation: b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004])
has associated axiom(fol): (forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004]

Axiom
annotated source: object aggregate
annotated property: editor note
annotated target: An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000011

Axiom
annotated source: object aggregate
annotated property: editor note
annotated target: An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000301

Axiom
annotated source: object aggregate
annotated property: definition source
annotated target: ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, 'A Theory of Granular Partitions', in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158.
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000300

Axiom
annotated source: object aggregate
annotated property: elucidation
annotated target: b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/025-004

Axiom
annotated source: object aggregate
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/025-004

three-dimensional spatial region
type: Class
subclass of: spatial region
BFO OWL specification label: 3d-s-region
BFO CLIF specification label: ThreeDimensionalSpatialRegion
example of usage: a cube-shaped region of space
example of usage: a sphere-shaped region of space,
elucidation: A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001])
has associated axiom(fol): (forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001]

Axiom
annotated source: three-dimensional spatial region
annotated property: elucidation
annotated target: A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/040-001

Axiom
annotated source: three-dimensional spatial region
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/040-001

site
type: Class
subclass of: immaterial entity
BFO OWL specification label: site
BFO CLIF specification label: Site
example of usage: Manhattan Canyon)
example of usage: a hole in the interior of a portion of cheese
example of usage: a rabbit hole
example of usage: an air traffic control region defined in the airspace above an airport
example of usage: the Grand Canyon
example of usage: the Piazza San Marco
example of usage: the cockpit of an aircraft
example of usage: the hold of a ship
example of usage: the interior of a kangaroo pouch
example of usage: the interior of the trunk of your car
example of usage: the interior of your bedroom
example of usage: the interior of your office
example of usage: the interior of your refrigerator
example of usage: the lumen of your gut
example of usage: your left nostril (a fiat part – the opening – of your left nasal cavity)
elucidation: b is a site means: b is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or it is a three-dimensional immaterial part thereof. (axiom label in BFO2 Reference: [034-002])
has associated axiom(fol): (forall (x) (if (Site x) (ImmaterialEntity x))) // axiom label in BFO2 CLIF: [034-002]

Axiom
annotated source: site
annotated property: elucidation
annotated target: b is a site means: b is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or it is a three-dimensional immaterial part thereof. (axiom label in BFO2 Reference: [034-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/034-002

Axiom
annotated source: site
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Site x) (ImmaterialEntity x))) // axiom label in BFO2 CLIF: [034-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/034-002

object
type: Class
subclass of: material entity
BFO OWL specification label: object
BFO CLIF specification label: Object
example of usage: atom
example of usage: cell
example of usage: cells and organisms
example of usage: engineered artifacts
example of usage: grain of sand
example of usage: molecule
example of usage: organelle
example of usage: organism
example of usage: planet
example of usage: solid portions of matter
example of usage: star
editor note: BFO 2 Reference: BFO rests on the presupposition that at multiple micro-, meso- and macroscopic scales reality exhibits certain stable, spatially separated or separable material units, combined or combinable into aggregates of various sorts (for example organisms into what are called ‘populations’). Such units play a central role in almost all domains of natural science from particle physics to cosmology. Many scientific laws govern the units in question, employing general terms (such as ‘molecule’ or ‘planet’) referring to the types and subtypes of units, and also to the types and subtypes of the processes through which such units develop and interact. The division of reality into such natural units is at the heart of biological science, as also is the fact that these units may form higher-level units (as cells form multicellular organisms) and that they may also form aggregates of units, for example as cells form portions of tissue and organs form families, herds, breeds, species, and so on. At the same time, the division of certain portions of reality into engineered units (manufactured artifacts) is the basis of modern industrial technology, which rests on the distributed mass production of engineered parts through division of labor and on their assembly into larger, compound units such as cars and laptops. The division of portions of reality into units is one starting point for the phenomenon of counting.
editor note: BFO 2 Reference: Each object is such that there are entities of which we can assert unproblematically that they lie in its interior, and other entities of which we can assert unproblematically that they lie in its exterior. This may not be so for entities lying at or near the boundary between the interior and exterior. This means that two objects – for example the two cells depicted in Figure 3 – may be such that there are material entities crossing their boundaries which belong determinately to neither cell. Something similar obtains in certain cases of conjoined twins (see below).
editor note: BFO 2 Reference: To say that b is causally unified means: b is a material entity which is such that its material parts are tied together in such a way that, in environments typical for entities of the type in question,if c, a continuant part of b that is in the interior of b at t, is larger than a certain threshold size (which will be determined differently from case to case, depending on factors such as porosity of external cover) and is moved in space to be at t at a location on the exterior of the spatial region that had been occupied by b at t, then either b’s other parts will be moved in coordinated fashion or b will be damaged (be affected, for example, by breakage or tearing) in the interval between t and t.causal changes in one part of b can have consequences for other parts of b without the mediation of any entity that lies on the exterior of b. Material entities with no proper material parts would satisfy these conditions trivially. Candidate examples of types of causal unity for material entities of more complex sorts are as follows (this is not intended to be an exhaustive list):CU1: Causal unity via physical coveringHere the parts in the interior of the unified entity are combined together causally through a common membrane or other physical covering\. The latter points outwards toward and may serve a protective function in relation to what lies on the exterior of the entity [13, 47
editor note: BFO 2 Reference: an object is a maximal causally unified material entity
editor note: BFO 2 Reference: ‘objects’ are sometimes referred to as ‘grains’ [74
elucidation: b is an object means: b is a material entity which manifests causal unity of one or other of the types CUn listed above & is of a type (a material universal) instances of which are maximal relative to this criterion of causal unity. (axiom label in BFO2 Reference: [024-001])

Axiom
annotated source: object
annotated property: elucidation
annotated target: b is an object means: b is a material entity which manifests causal unity of one or other of the types CUn listed above & is of a type (a material universal) instances of which are maximal relative to this criterion of causal unity. (axiom label in BFO2 Reference: [024-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/024-001

generically dependent continuant
type: Class
subclass of: continuant
BFO OWL specification label: gdc
BFO CLIF specification label: GenericallyDependentContinuant
example of usage: The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity.
example of usage: the pdf file on your laptop, the pdf file that is a copy thereof on my laptop
example of usage: the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule.
definition: A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time.
definition: b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])
has associated axiom(fol): (iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001]

Axiom
annotated source: generically dependent continuant
annotated property: definition
annotated target: b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/074-001

Axiom
annotated source: generically dependent continuant
annotated property: has associated axiom(fol)
annotated target: (iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/074-001

function
type: Class
subclass of: disposition
BFO OWL specification label: function
BFO CLIF specification label: Function
example of usage: the function of a hammer to drive in nails
example of usage: the function of a heart pacemaker to regulate the beating of a heart through electricity
example of usage: the function of amylase in saliva to break down starch into sugar
editor note: BFO 2 Reference: In the past, we have distinguished two varieties of function, artifactual function and biological function. These are not asserted subtypes of BFO:function however, since the same function – for example: to pump, to transport – can exist both in artifacts and in biological entities. The asserted subtypes of function that would be needed in order to yield a separate monoheirarchy are not artifactual function, biological function, etc., but rather transporting function, pumping function, etc.
elucidation: A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])
has associated axiom(fol): (forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001]

Axiom
annotated source: function
annotated property: elucidation
annotated target: A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/064-001

Axiom
annotated source: function
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/064-001

process boundary
type: Class
subclass of: occurrent
BFO OWL specification label: p-boundary
BFO CLIF specification label: ProcessBoundary
example of usage: the boundary between the 2nd and 3rd year of your life.
definition: p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])
has associated axiom(nl): Every process boundary occupies_temporal_region a zero-dimensional temporal region. (axiom label in BFO2 Reference: [085-002])
has associated axiom(fol): (forall (x) (if (ProcessBoundary x) (exists (y) (and (ZeroDimensionalTemporalRegion y) (occupiesTemporalRegion x y))))) // axiom label in BFO2 CLIF: [085-002]
has associated axiom(fol): (iff (ProcessBoundary a) (exists (p) (and (Process p) (temporalPartOf a p) (not (exists (b) (properTemporalPartOf b a)))))) // axiom label in BFO2 CLIF: [084-001]

Axiom
annotated source: process boundary
annotated property: definition
annotated target: p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/084-001

Axiom
annotated source: process boundary
annotated property: has associated axiom(nl)
annotated target: Every process boundary occupies_temporal_region a zero-dimensional temporal region. (axiom label in BFO2 Reference: [085-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/085-002

Axiom
annotated source: process boundary
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (ProcessBoundary x) (exists (y) (and (ZeroDimensionalTemporalRegion y) (occupiesTemporalRegion x y))))) // axiom label in BFO2 CLIF: [085-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/085-002

Axiom
annotated source: process boundary
annotated property: has associated axiom(fol)
annotated target: (iff (ProcessBoundary a) (exists (p) (and (Process p) (temporalPartOf a p) (not (exists (b) (properTemporalPartOf b a)))))) // axiom label in BFO2 CLIF: [084-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/084-001

one-dimensional temporal region
type: Class
subclass of: temporal region
disjoint with: zero-dimensional temporal region
BFO OWL specification label: 1d-t-region
BFO CLIF specification label: OneDimensionalTemporalRegion
example of usage: the temporal region during which a process occurs.
editor note: BFO 2 Reference: A temporal interval is a special kind of one-dimensional temporal region, namely one that is self-connected (is without gaps or breaks).
elucidation: A one-dimensional temporal region is a temporal region that is extended. (axiom label in BFO2 Reference: [103-001])
has associated axiom(fol): (forall (x) (if (OneDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [103-001]

Axiom
annotated source: one-dimensional temporal region
annotated property: elucidation
annotated target: A one-dimensional temporal region is a temporal region that is extended. (axiom label in BFO2 Reference: [103-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/103-001

Axiom
annotated source: one-dimensional temporal region
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (OneDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [103-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/103-001

material entity
type: Class
subclass of: independent continuant
disjoint with: immaterial entity
BFO OWL specification label: material
BFO CLIF specification label: MaterialEntity
example of usage: a flame
example of usage: a forest fire
example of usage: a human being
example of usage: a hurricane
example of usage: a photon
example of usage: a puff of smoke
example of usage: a sea wave
example of usage: a tornado
example of usage: an aggregate of human beings.
example of usage: an energy wave
example of usage: an epidemic
example of usage: the undetached arm of a human being
definition: An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.
editor note: BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60
editor note: BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity.
editor note: BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here.
elucidation: A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])
has associated axiom(nl): Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])
has associated axiom(nl): every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])
has associated axiom(fol): (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002]
has associated axiom(fol): (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002]
has associated axiom(fol): (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002]

Axiom
annotated source: material entity
annotated property: elucidation
annotated target: A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/019-002

Axiom
annotated source: material entity
annotated property: has associated axiom(nl)
annotated target: Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/020-002

Axiom
annotated source: material entity
annotated property: has associated axiom(nl)
annotated target: every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/021-002

Axiom
annotated source: material entity
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/019-002

Axiom
annotated source: material entity
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/021-002

Axiom
annotated source: material entity
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/020-002

continuant fiat boundary
type: Class
subclass of: immaterial entity
BFO OWL specification label: cf-boundary
BFO CLIF specification label: ContinuantFiatBoundary
definition: b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])
editor note: BFO 2 Reference: In BFO 1.1 the assumption was made that the external surface of a material entity such as a cell could be treated as if it were a boundary in the mathematical sense. The new document propounds the view that when we talk about external surfaces of material objects in this way then we are talking about something fiat. To be dealt with in a future version: fiat boundaries at different levels of granularity.More generally, the focus in discussion of boundaries in BFO 2.0 is now on fiat boundaries, which means: boundaries for which there is no assumption that they coincide with physical discontinuities. The ontology of boundaries becomes more closely allied with the ontology of regions.
editor note: BFO 2 Reference: a continuant fiat boundary is a boundary of some material entity (for example: the plane separating the Northern and Southern hemispheres; the North Pole), or it is a boundary of some immaterial entity (for example of some portion of airspace). Three basic kinds of continuant fiat boundary can be distinguished (together with various combination kinds [29
editor note: Continuant fiat boundary doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the mereological sum of two-dimensional continuant fiat boundary and a one dimensional continuant fiat boundary that doesn't overlap it. The situation is analogous to temporal and spatial regions.
has associated axiom(nl): Every continuant fiat boundary is located at some spatial region at every time at which it exists
has associated axiom(fol): (iff (ContinuantFiatBoundary a) (and (ImmaterialEntity a) (exists (b) (and (or (ZeroDimensionalSpatialRegion b) (OneDimensionalSpatialRegion b) (TwoDimensionalSpatialRegion b)) (forall (t) (locatedInAt a b t)))) (not (exists (c t) (and (SpatialRegion c) (continuantPartOfAt c a t)))))) // axiom label in BFO2 CLIF: [029-001]

Axiom
annotated source: continuant fiat boundary
annotated property: definition
annotated target: b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/029-001

Axiom
annotated source: continuant fiat boundary
annotated property: editor note
annotated target: Continuant fiat boundary doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the mereological sum of two-dimensional continuant fiat boundary and a one dimensional continuant fiat boundary that doesn't overlap it. The situation is analogous to temporal and spatial regions.
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000008

Axiom
annotated source: continuant fiat boundary
annotated property: has associated axiom(fol)
annotated target: (iff (ContinuantFiatBoundary a) (and (ImmaterialEntity a) (exists (b) (and (or (ZeroDimensionalSpatialRegion b) (OneDimensionalSpatialRegion b) (TwoDimensionalSpatialRegion b)) (forall (t) (locatedInAt a b t)))) (not (exists (c t) (and (SpatialRegion c) (continuantPartOfAt c a t)))))) // axiom label in BFO2 CLIF: [029-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/029-001

immaterial entity
type: Class
subclass of: independent continuant
BFO OWL specification label: immaterial
BFO CLIF specification label: ImmaterialEntity
editor note: BFO 2 Reference: Immaterial entities are divided into two subgroups:boundaries and sites, which bound, or are demarcated in relation, to material entities, and which can thus change location, shape and size and as their material hosts move or change shape or size (for example: your nasal passage; the hold of a ship; the boundary of Wales (which moves with the rotation of the Earth) [38, 7, 10

one-dimensional continuant fiat boundary
type: Class
subclass of: continuant fiat boundary
disjoint with: two-dimensional continuant fiat boundary
disjoint with: zero-dimensional continuant fiat boundary
BFO OWL specification label: 1d-cf-boundary
BFO CLIF specification label: OneDimensionalContinuantFiatBoundary
example of usage: The Equator
example of usage: all geopolitical boundaries
example of usage: all lines of latitude and longitude
example of usage: the line separating the outer surface of the mucosa of the lower lip from the outer surface of the skin of the chin.
example of usage: the median sulcus of your tongue
elucidation: a one-dimensional continuant fiat boundary is a continuous fiat line whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [032-001])
has associated axiom(fol): (iff (OneDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (OneDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [032-001]

Axiom
annotated source: one-dimensional continuant fiat boundary
annotated property: elucidation
annotated target: a one-dimensional continuant fiat boundary is a continuous fiat line whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [032-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/032-001

Axiom
annotated source: one-dimensional continuant fiat boundary
annotated property: has associated axiom(fol)
annotated target: (iff (OneDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (OneDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [032-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/032-001

process profile
type: Class
subclass of: process
disjoint with: history
BFO OWL specification label: process-profile
BFO CLIF specification label: ProcessProfile
example of usage: On a somewhat higher level of complexity are what we shall call rate process profiles, which are the targets of selective abstraction focused not on determinate quality magnitudes plotted over time, but rather on certain ratios between these magnitudes and elapsed times. A speed process profile, for example, is represented by a graph plotting against time the ratio of distance covered per unit of time. Since rates may change, and since such changes, too, may have rates of change, we have to deal here with a hierarchy of process profile universals at successive levels
example of usage: One important sub-family of rate process profiles is illustrated by the beat or frequency profiles of cyclical processes, illustrated by the 60 beats per minute beating process of John’s heart, or the 120 beats per minute drumming process involved in one of John’s performances in a rock band, and so on. Each such process includes what we shall call a beat process profile instance as part, a subtype of rate process profile in which the salient ratio is not distance covered but rather number of beat cycles per unit of time. Each beat process profile instance instantiates the determinable universal beat process profile. But it also instantiates multiple more specialized universals at lower levels of generality, selected from rate process profilebeat process profileregular beat process profile3 bpm beat process profile4 bpm beat process profileirregular beat process profileincreasing beat process profileand so on.In the case of a regular beat process profile, a rate can be assigned in the simplest possible fashion by dividing the number of cycles by the length of the temporal region occupied by the beating process profile as a whole. Irregular process profiles of this sort, for example as identified in the clinic, or in the readings on an aircraft instrument panel, are often of diagnostic significance.
example of usage: The simplest type of process profiles are what we shall call ‘quality process profiles’, which are the process profiles which serve as the foci of the sort of selective abstraction that is involved when measurements are made of changes in single qualities, as illustrated, for example, by process profiles of mass, temperature, aortic pressure, and so on.
definition: b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])
elucidation: b process_profile_of c holds when b proper_occurrent_part_of c& there is some proper_occurrent_part d of c which has no parts in common with b & is mutually dependent on b& is such that b, c and d occupy the same temporal region (axiom label in BFO2 Reference: [094-005])
has associated axiom(fol): (forall (x y) (if (processProfileOf x y) (and (properContinuantPartOf x y) (exists (z t) (and (properOccurrentPartOf z y) (TemporalRegion t) (occupiesSpatioTemporalRegion x t) (occupiesSpatioTemporalRegion y t) (occupiesSpatioTemporalRegion z t) (not (exists (w) (and (occurrentPartOf w x) (occurrentPartOf w z))))))))) // axiom label in BFO2 CLIF: [094-005]
has associated axiom(fol): (iff (ProcessProfile a) (exists (b) (and (Process b) (processProfileOf a b)))) // axiom label in BFO2 CLIF: [093-002]

Axiom
annotated source: process profile
annotated property: definition
annotated target: b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/093-002

Axiom
annotated source: process profile
annotated property: elucidation
annotated target: b process_profile_of c holds when b proper_occurrent_part_of c& there is some proper_occurrent_part d of c which has no parts in common with b & is mutually dependent on b& is such that b, c and d occupy the same temporal region (axiom label in BFO2 Reference: [094-005])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/094-005

Axiom
annotated source: process profile
annotated property: has associated axiom(fol)
annotated target: (forall (x y) (if (processProfileOf x y) (and (properContinuantPartOf x y) (exists (z t) (and (properOccurrentPartOf z y) (TemporalRegion t) (occupiesSpatioTemporalRegion x t) (occupiesSpatioTemporalRegion y t) (occupiesSpatioTemporalRegion z t) (not (exists (w) (and (occurrentPartOf w x) (occurrentPartOf w z))))))))) // axiom label in BFO2 CLIF: [094-005]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/094-005

Axiom
annotated source: process profile
annotated property: has associated axiom(fol)
annotated target: (iff (ProcessProfile a) (exists (b) (and (Process b) (processProfileOf a b)))) // axiom label in BFO2 CLIF: [093-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/093-002

relational quality
type: Class
subclass of: quality
BFO OWL specification label: r-quality
BFO CLIF specification label: RelationalQuality
example of usage: John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married.
example of usage: a marriage bond, an instance of requited love, an obligation between one person and another.
definition: b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001])
has associated axiom(fol): (iff (RelationalQuality a) (exists (b c t) (and (IndependentContinuant b) (IndependentContinuant c) (qualityOfAt a b t) (qualityOfAt a c t)))) // axiom label in BFO2 CLIF: [057-001]

Axiom
annotated source: relational quality
annotated property: definition
annotated target: b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/057-001

Axiom
annotated source: relational quality
annotated property: has associated axiom(fol)
annotated target: (iff (RelationalQuality a) (exists (b c t) (and (IndependentContinuant b) (IndependentContinuant c) (qualityOfAt a b t) (qualityOfAt a c t)))) // axiom label in BFO2 CLIF: [057-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/057-001

two-dimensional continuant fiat boundary
type: Class
subclass of: continuant fiat boundary
BFO OWL specification label: 2d-cf-boundary
BFO CLIF specification label: TwoDimensionalContinuantFiatBoundary
elucidation: a two-dimensional continuant fiat boundary (surface) is a self-connected fiat surface whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [033-001])
has associated axiom(fol): (iff (TwoDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (TwoDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [033-001]

Axiom
annotated source: two-dimensional continuant fiat boundary
annotated property: elucidation
annotated target: a two-dimensional continuant fiat boundary (surface) is a self-connected fiat surface whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [033-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/033-001

Axiom
annotated source: two-dimensional continuant fiat boundary
annotated property: has associated axiom(fol)
annotated target: (iff (TwoDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (TwoDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [033-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/033-001

zero-dimensional continuant fiat boundary
type: Class
subclass of: continuant fiat boundary
BFO OWL specification label: 0d-cf-boundary
BFO CLIF specification label: ZeroDimensionalContinuantFiatBoundary
example of usage: the geographic North Pole
example of usage: the point of origin of some spatial coordinate system.
example of usage: the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet
editor note: zero dimension continuant fiat boundaries are not spatial points. Considering the example 'the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet' : There are many frames in which that point is zooming through many points in space. Whereas, no matter what the frame, the quadripoint is always in the same relation to the boundaries of Colorado, Utah, New Mexico, and Arizona.
elucidation: a zero-dimensional continuant fiat boundary is a fiat point whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [031-001])
has associated axiom(fol): (iff (ZeroDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (ZeroDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [031-001]

Axiom
annotated source: zero-dimensional continuant fiat boundary
annotated property: editor note
annotated target: zero dimension continuant fiat boundaries are not spatial points. Considering the example 'the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet' : There are many frames in which that point is zooming through many points in space. Whereas, no matter what the frame, the quadripoint is always in the same relation to the boundaries of Colorado, Utah, New Mexico, and Arizona.
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000001
comment: requested by Melanie Courtot

Axiom
annotated source: zero-dimensional continuant fiat boundary
annotated property: elucidation
annotated target: a zero-dimensional continuant fiat boundary is a fiat point whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [031-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/031-001

Axiom
annotated source: zero-dimensional continuant fiat boundary
annotated property: has associated axiom(fol)
annotated target: (iff (ZeroDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (ZeroDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [031-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/031-001

zero-dimensional temporal region
type: Class
subclass of: temporal region
BFO OWL specification label: 0d-t-region
BFO CLIF specification label: ZeroDimensionalTemporalRegion
example of usage: a temporal region that is occupied by a process boundary
example of usage: right now
example of usage: the moment at which a child is born
example of usage: the moment at which a finger is detached in an industrial accident
example of usage: the moment of death.
alternative label: temporal instant.
elucidation: A zero-dimensional temporal region is a temporal region that is without extent. (axiom label in BFO2 Reference: [102-001])
has associated axiom(fol): (forall (x) (if (ZeroDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [102-001]

Axiom
annotated source: zero-dimensional temporal region
annotated property: elucidation
annotated target: A zero-dimensional temporal region is a temporal region that is without extent. (axiom label in BFO2 Reference: [102-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/102-001

Axiom
annotated source: zero-dimensional temporal region
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (ZeroDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [102-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/102-001

history
type: Class
subclass of: process
BFO OWL specification label: history
BFO CLIF specification label: History
elucidation: A history is a process that is the sum of the totality of processes taking place in the spatiotemporal region occupied by a material entity or site, including processes on the surface of the entity or within the cavities to which it serves as host. (axiom label in BFO2 Reference: [138-001])

Axiom
annotated source: history
annotated property: elucidation
annotated target: A history is a process that is the sum of the totality of processes taking place in the spatiotemporal region occupied by a material entity or site, including processes on the surface of the entity or within the cavities to which it serves as host. (axiom label in BFO2 Reference: [138-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/138-001

hepatopancreas
type: Class
subclass of: material anatomical entity
definition: Digestive gland of crustaceans with functions approximately analogous to liver and pancreas of vertebrates - enzyme secretion, food absorption and storage.
imported from: bto.owl

proboscis
type: Class
subclass of: material anatomical entity
definition: 1: The trunk of an elephant; also: any long flexible snout. 2: Any of various elongated or extensible tubular processes as the sucking organ of a butterfly of the oral region of an invertebrate.
imported from: bto.owl

cell
type: Class
subclass of: material anatomical entity
definition: A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.
imported from: cl.owl

hepatocyte
type: Class
subclass of: cell
definition: The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated.
imported from: cl.owl

erythrocyte
type: Class
subclass of: cell
definition: A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.
imported from: cl.owl

macrophage
type: Class
subclass of: cell
definition: A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells.
imported from: cl.owl

biological_process
type: Class
subclass of: process
definition: A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
imported from: go.owl

cell division
type: Class
subclass of: biological_process
definition: The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
imported from: go.owl

data item
type: Class
subclass of: information content entity
editor preferred term: data item

information content entity
type: Class
subclass of: generically dependent continuant
editor preferred term: information content entity

curation status specification
type: Class
equivalent class: Class
  one of: example to be eventually removed
  one of: metadata complete
  one of: organizational term
  one of: ready for release
  one of: metadata incomplete
  one of: uncurated
  one of: pending final vetting
  one of: to be replaced with external ontology term
  one of: requires discussion
subclass of: data about an ontology part
editor preferred term: curation status specification
has curation status: pending final vetting
definition: The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value.
editor note: Better to represent curation as a process with parts and then relate labels to that process (in IAO meeting)
term editor: PERSON:Bill Bug
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
definition source: OBI_0000266

data about an ontology part
type: Class
subclass of: data item
editor preferred term: data about an ontology part
definition: Data about an ontology part is a data item about a part of an ontology, for example a term
term editor: Person:Alan Ruttenberg

obsolescence reason specification
type: Class
equivalent class: Class
  one of: failed exploratory term
  one of: placeholder removed
  one of: terms merged
  one of: term imported
  one of: term split
  one of: out of scope
subclass of: data about an ontology part
editor preferred term: obsolescence reason specification
has curation status: pending final vetting
definition: The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value.
editor note: The creation of this class has been inspired in part by Werner Ceusters' paper, Applying evolutionary terminology auditing to the Gene Ontology.
term editor: PERSON: Alan Ruttenberg
term editor: PERSON: Melanie Courtot

denotator type
type: Class
equivalent class: Class
  one of: universal
  one of: defined class
  one of: named class expression
subclass of: data about an ontology part
editor preferred term: denotator type
example of usage: The Basic Formal Ontology ontology makes a distinction between Universals and defined classes, where the formal are "natural kinds" and the latter arbitrary collections of entities.
definition: A denotator type indicates how a term should be interpreted from an ontological perspective.
term editor: Alan Ruttenberg
definition source: Barry Smith, Werner Ceusters

ontology module
type: Class
subclass of: data about an ontology part
editor preferred term: ontology module
editor note: I have placed this under 'data about an ontology part', but this can be discussed. I think this is OK if 'part' is interpreted reflexively, as an ontology module is the whole ontology rather than part of it.
alternative label: ontology file
curator note: This class and it's subclasses are applied to OWL ontologies. Using an rdf:type triple will result in problems with OWL-DL. I propose that dcterms:type is instead used to connect an ontology URI with a class from this hierarchy. The class hierarchy is not disjoint, so multiple assertions can be made about a single ontology.

base ontology module
type: Class
subclass of: ontology module
editor preferred term: base ontology module
definition: An ontology module that comprises only of asserted axioms local to the ontology, excludes import directives, and excludes axioms or declarations from external ontologies.

editors ontology module
type: Class
subclass of: ontology module
editor preferred term: editors ontology module
definition: An ontology module that is intended to be directly edited, typically managed in source control, and typically not intended for direct consumption by end-users.
alternative label: source ontology module

main release ontology module
type: Class
subclass of: ontology module
editor preferred term: main release ontology module
definition: An ontology module that is intended to be the primary release product and the one consumed by the majority of tools.
editor note: TODO: Add logical axioms that state that a main release ontology module is derived from (directly or indirectly) an editors module

bridge ontology module
type: Class
subclass of: ontology module
editor preferred term: bridge ontology module
definition: An ontology module that consists entirely of axioms that connect or bridge two distinct ontology modules. For example, the Uberon-to-ZFA bridge module.

import ontology module
type: Class
subclass of: subset ontology module
editor preferred term: import ontology module
definition: A subset ontology module that is intended to be imported from another ontology.
editor note: TODO: add axioms that indicate this is the output of a module extraction process.
alternative label: import file

subset ontology module
type: Class
subclass of: ontology module
editor preferred term: subset ontology module
definition: An ontology module that is extracted from a main ontology module and includes only a subset of entities or axioms.
alternative label: ontology slim
alternative label: subset ontology

curation subset ontology module
type: Class
subclass of: subset ontology module
editor preferred term: curation subset ontology module
definition: A subset ontology that is intended as a whitelist for curators using the ontology. Such a subset will exclude classes that curators should not use for curation.

analysis subset ontology module
type: Class
subclass of: subset ontology module
editor preferred term: analysis ontology module
definition: An ontology module that is intended for usage in analysis or discovery applications.

single layer subset ontology module
type: Class
subclass of: subset ontology module
editor preferred term: single layer ontology module
definition: A subset ontology that is largely comprised of a single layer or strata in an ontology class hierarchy. The purpose is typically for rolling up for visualization. The classes in the layer need not be disjoint.
alternative label: ribbon subset

exclusion subset ontology module
type: Class
subclass of: subset ontology module
editor preferred term: exclusion subset ontology module
definition: A subset of an ontology that is intended to be excluded for some purpose. For example, a blacklist of classes.
alternative label: antislim

external import ontology module
type: Class
subclass of: import ontology module
editor preferred term: external import ontology module
definition: An imported ontology module that is derived from an external ontology. Derivation methods include the OWLAPI SLME approach.
alternative label: external import

species subset ontology module
type: Class
subclass of: subset ontology module
editor preferred term: species subset ontology module
definition: A subset ontology that is crafted to either include or exclude a taxonomic grouping of species.
alternative label: taxon subset

reasoned ontology module
type: Class
subclass of: ontology module
editor preferred term: reasoned ontology module
definition: An ontology module that contains axioms generated by a reasoner. The generated axioms are typically direct SubClassOf axioms, but other possibilities are available.

generated ontology module
type: Class
subclass of: ontology module
editor preferred term: generated ontology module
definition: An ontology module that is automatically generated, for example via a SPARQL query or via template and a CSV.
editor note: TODO: Add axioms (using PROV-O?) that indicate this is the output-of some reasoning process

template generated ontology module
type: Class
subclass of: generated ontology module
editor preferred term: template generated ontology module
definition: An ontology module that is automatically generated from a template specification and fillers for slots in that template.

taxonomic bridge ontology module
type: Class
subclass of: bridge ontology module
editor preferred term: taxonomic bridge ontology module

ontology module subsetted by expressivity
type: Class
subclass of: subset ontology module
editor preferred term: ontology module subsetted by expressivity

obo basic subset ontology module
type: Class
subclass of: ontology module subsetted by expressivity
editor preferred term: obo basic subset ontology module
definition: A subset ontology that is designed for basic applications to continue to make certain simplifying assumptions; many of these simplifying assumptions were based on the initial version of the Gene Ontology, and have become enshrined in many popular and useful tools such as term enrichment tools. Examples of such assumptions include: traversing the ontology graph ignoring relationship types using a naive algorithm will not lead to cycles (i.e. the ontology is a DAG); every referenced term is declared in the ontology (i.e. there are no dangling clauses). An ontology is OBO Basic if and only if it has the following characteristics: DAG Unidirectional No Dangling Clauses Fully Asserted Fully Labeled No equivalence axioms Singly labeled edges No qualifier lists No disjointness axioms No owl-axioms header No imports

ontology module subsetted by OWL profile
type: Class
subclass of: ontology module subsetted by expressivity
editor preferred term: ontology module subsetted by OWL profile

EL++ ontology module
type: Class
subclass of: ontology module subsetted by OWL profile
editor preferred term: EL++ ontology module

parasite role
type: Class
subclass of: role
definition: A symbiont role borne by an organism in virtue of the fact that it derives a growth, survival, or fitness advantage from symbiosis while the other symbiont's growth, survival, or fitness is reduced.
imported from: ido.owl

infectious agent role
type: Class
subclass of: pathogen role
definition: A role borne by an infectious agent when contained in a host in which its infectious disposition can be realized.
imported from: ido.owl

pathogen role
type: Class
subclass of: role
definition: A role borne by pathogen in virtue of the fact that it or one of its products is sufficiently close to an organism towards which it has the pathogenic disposition to allow realization of the pathogenic disposition.
imported from: ido.owl

definitive host role
type: Class
subclass of: host role
definition: A symbiont host role borne by an organism in virtue of the fact that its partner in symbiosis reaches developmental maturity or reproduces sexually in the host.
imported from: ido.owl

intermediate host role
type: Class
subclass of: host role
definition: A symbiont host role borne by an organism in virtue of the fact that its partner in symbiosis utilizes the host to undergo a developmental stage transition, and the host is required for continuation of the partner's life cycle.
imported from: ido.owl

parasite host role
type: Class
subclass of: host role
definition: A symbiont host role borne by an organism in virtue of the fact that its partner in symbiosis derives from the host a growth, survival, or fitness advantage while the host's growth, survival, or fitness is reduced.
imported from: ido.owl

infectious agent vector role
type: Class
subclass of: role
definition: An infectious agent transporter role that is borne by an organism active in the transfer of an infectious agent to an organism of another Species and in which the agent is infectious.
imported from: ido.owl

biological vector of infectious agent role
type: Class
subclass of: infectious agent vector role
definition: An infectious agent vector role borne by an organism in virtue of the fact that the infectious agent multiplies in the vector.
imported from: ido.owl

Mus musculus
type: Class
subclass of: Mammalia
alternative label: house mouse
alternative label: mouse
imported from: ncbitaxon.owl

Bulinus
type: Class
subclass of: Mollusca
subclass of: Restriction
  on property: has role
  some values from: intermediate host role
imported from: ncbitaxon.owl

Neospora caninum
type: Class
subclass of: parasite organism
subclass of: Restriction
  on property: has host
  some values from: Canis
imported from: ncbitaxon.owl

Mammalia
type: Class
subclass of: Vertebrata <vertebrates>
subclass of: Restriction
  on property: has role
  some values from: host role
alternative label: mammals
imported from: ncbitaxon.owl

Sarcocystis neurona
type: Class
subclass of: parasite organism
subclass of: Restriction
  on property: has host
  some values from: Canis lupus familiaris
imported from: ncbitaxon.owl

Insecta
type: Class
subclass of: organism
alternative label: true insects
imported from: ncbitaxon.owl

Oncomelania
type: Class
subclass of: Mollusca
subclass of: Restriction
  on property: has role
  some values from: intermediate host role
imported from: ncbitaxon.owl

Trypanosomatidae
type: Class
subclass of: parasite organism
imported from: ncbitaxon.owl

Leishmania <genus>
type: Class
subclass of: Trypanosomatidae
alternative label: Leishmania
imported from: ncbitaxon.owl

Leishmania amazonensis
type: Class
subclass of: Leishmania <genus>
subclass of: Restriction
  on property: has role
  some values from: human parasite role
subclass of: Restriction
  on property: has host
  some values from: Mammalia
subclass of: Restriction
  on property: has vector
  some values from: Phlebotominae
imported from: ncbitaxon.owl

Leishmania donovani
type: Class
subclass of: Leishmania <genus>
subclass of: Restriction
  on property: has role
  some values from: human parasite role
subclass of: Restriction
  on property: has host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has vector
  some values from: Phlebotominae
imported from: ncbitaxon.owl

Leishmania major
type: Class
subclass of: Leishmania <genus>
subclass of: Restriction
  on property: has role
  some values from: human parasite role
subclass of: Restriction
  on property: has host
  some values from: Mammalia
subclass of: Restriction
  on property: has vector
  some values from: Phlebotominae
imported from: ncbitaxon.owl

Leishmania infantum
type: Class
subclass of: Leishmania <genus>
subclass of: Restriction
  on property: has role
  some values from: human parasite role
subclass of: Restriction
  on property: has host
  some values from: Mammalia
subclass of: Restriction
  on property: has vector
  some values from: Phlebotominae
imported from: ncbitaxon.owl

Trypanosoma
type: Class
subclass of: Trypanosomatidae
imported from: ncbitaxon.owl

Trypanosoma brucei
type: Class
subclass of: Trypanosoma
subclass of: Restriction
  on property: has role
  some values from: human parasite role
subclass of: Restriction
  on property: has host
  some values from: Mammalia
subclass of: Restriction
  on property: has vector
  some values from: Glossina <genus>
imported from: ncbitaxon.owl

Trypanosoma cruzi
type: Class
subclass of: Trypanosoma
subclass of: Restriction
  on property: has role
  some values from: human parasite role
subclass of: Restriction
  on property: has host
  some values from: Mammalia
subclass of: Restriction
  on property: has vector
  some values from: Triatominae
imported from: ncbitaxon.owl

Eimeria
type: Class
subclass of: parasite organism
subclass of: Restriction
  on property: has host
  some values from: Vertebrata <vertebrates>
imported from: ncbitaxon.owl

Eimeria tenella
type: Class
subclass of: Eimeria
subclass of: Restriction
  on property: has host
  some values from: Gallus gallus
imported from: ncbitaxon.owl

Eimeria maxima
type: Class
subclass of: Eimeria
subclass of: Restriction
  on property: has host
  some values from: Gallus gallus
imported from: ncbitaxon.owl

Toxoplasma gondii
type: Class
subclass of: parasite organism
subclass of: Restriction
  on property: has role
  some values from: human parasite role
subclass of: Restriction
  on property: has host
  some values from: Mammalia
subclass of: Restriction
  on property: has vector
  some values from: Triatominae
imported from: ncbitaxon.owl

Plasmodium
type: Class
subclass of: parasite organism
subclass of: Restriction
  on property: has host
  some values from: Vertebrata <vertebrates>
subclass of: Restriction
  on property: has vector
  some values from: Anopheles <genus>
imported from: ncbitaxon.owl

Plasmodium berghei
type: Class
subclass of: Plasmodium
subclass of: Restriction
  on property: has role
  some values from: human parasite role
subclass of: Restriction
  on property: has host
  some values from: Mammalia
subclass of: Restriction
  on property: has vector
  some values from: Anopheles <genus>
imported from: ncbitaxon.owl

Plasmodium falciparum
type: Class
subclass of: Plasmodium
subclass of: Restriction
  on property: has role
  some values from: human parasite role
subclass of: Restriction
  on property: has host
  some values from: Homo sapiens
subclass of: Restriction
  on property: has vector
  some values from: Anopheles <genus>
alternative label: malaria parasite P. falciparum
imported from: ncbitaxon.owl

Plasmodium vivax
type: Class
subclass of: Plasmodium
subclass of: Restriction
  on property: has role
  some values from: human parasite role
subclass of: Restriction
  on property: has host
  some values from: Vertebrata <vertebrates>
subclass of: Restriction
  on property: has vector
  some values from: Anopheles <genus>
alternative label: malaria parasite P. vivax
imported from: ncbitaxon.owl

Schistosoma
type: Class
subclass of: parasite organism
subclass of: Restriction
  on property: has host
  some values from: Mammalia
imported from: ncbitaxon.owl

Schistosoma japonicum
type: Class
subclass of: Schistosoma
subclass of: Restriction
  on property: has role
  some values from: human parasite role
subclass of: Restriction
  on property: has host
  some values from: Mammalia
subclass of: Restriction
  on property: has vector
  some values from: Oncomelania
imported from: ncbitaxon.owl

Schistosoma mansoni
type: Class
subclass of: Schistosoma
subclass of: Restriction
  on property: has role
  some values from: human parasite role
subclass of: Restriction
  on property: has host
  some values from: Mammalia
subclass of: Restriction
  on property: has vector
  some values from: Biomphalaria
imported from: ncbitaxon.owl

Schistosoma haematobium
type: Class
subclass of: Schistosoma
subclass of: Restriction
  on property: has role
  some values from: human parasite role
subclass of: Restriction
  on property: has host
  some values from: Mammalia
subclass of: Restriction
  on property: has vector
  some values from: Bulinus
imported from: ncbitaxon.owl

Mollusca
type: Class
subclass of: organism
alternative label: molluscs
alternative label: mollusks
imported from: ncbitaxon.owl

Biomphalaria
type: Class
subclass of: Mollusca
subclass of: Restriction
  on property: has role
  some values from: intermediate host role
imported from: ncbitaxon.owl

Triatominae
type: Class
subclass of: Insecta
subclass of: Restriction
  on property: has role
  some values from: biological vector of infectious agent role
alternative label: kissing bugs
imported from: ncbitaxon.owl

Anopheles <genus>
type: Class
subclass of: Insecta
subclass of: Restriction
  on property: has role
  some values from: biological vector of infectious agent role
alternative label: Anopheles
imported from: ncbitaxon.owl

Phlebotominae
type: Class
subclass of: Insecta
subclass of: Restriction
  on property: has role
  some values from: biological vector of infectious agent role
alternative label: sand flies
alternative label: sandflies
imported from: ncbitaxon.owl

Glossina <genus>
type: Class
subclass of: Insecta
subclass of: Restriction
  on property: has role
  some values from: biological vector of infectious agent role
alternative label: Glossina
alternative label: tsetse flies
alternative label: tsetse fly
imported from: ncbitaxon.owl

Vertebrata <vertebrates>
type: Class
subclass of: organism
alternative label: Vertebrata
alternative label: vertebrates
imported from: ncbitaxon.owl

Gallus gallus
type: Class
subclass of: Vertebrata <vertebrates>
subclass of: Restriction
  on property: has role
  some values from: host role
alternative label: Gallus domesticus
alternative label: bantam
alternative label: chicken
alternative label: chickens
imported from: ncbitaxon.owl

Homo sapiens
type: Class
subclass of: Mammalia
subclass of: Restriction
  on property: has role
  some values from: definitive host role
alternative label: human
imported from: ncbitaxon.owl

Canis
type: Class
subclass of: Mammalia
subclass of: Restriction
  on property: has role
  some values from: definitive host role
imported from: ncbitaxon.owl

Canis lupus familiaris
type: Class
subclass of: Canis
alternative label: dog
alternative label: dogs
imported from: ncbitaxon.owl

Odocoileus virginianus
type: Class
subclass of: Mammalia
subclass of: Restriction
  on property: has role
  some values from: intermediate host role
alternative label: white-tailed deer
imported from: ncbitaxon.owl

Bos taurus
type: Class
subclass of: Mammalia
subclass of: Restriction
  on property: has role
  some values from: intermediate host role
alternative label: bovine
alternative label: cattle
alternative label: cow
alternative label: dairy cow
alternative label: domestic cattle
alternative label: domestic cow
alternative label: ox
alternative label: oxen
imported from: ncbitaxon.owl

host role
type: Class
subclass of: role
definition: host role is a role played by an organism and realized by providing nourishment, shelter or a means of reproduction to another organism within the organism playing the host role
imported from: obi.owl

organism
type: Class
subclass of: material entity
definition: A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs.
imported from: obi.owl

Leishmania major metacyclic promastigote
type: Class
subclass of: Leishmania major promastigote
subclass of: Restriction
  on property: participates in
  some values from: Leishmania major metacyclic promastigote stage
subclass of: Restriction
  on property: located in
  some values from: Phlebotominae proboscis
subclass of: Restriction
  on property: located in
  some values from: Mammalia macrophage
definition: A Leishmania major promastigote that undergoes a second developmental transition yielding the metacyclic promastigote. This form of parasite is infective to its mammalian host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: L. major metacyclic promastigote
definition source: PMID:11748963

Triatominae hindgut
type: Class
equivalent class: Class
  intersection of: hindgut
  intersection of: Restriction
    on property: part of
    some values from: Triatominae
subclass of: hindgut
definition: A hindgut that is a part of or originated from a Triatominae bug.
term editor: Priti Parikh

Homo sapiens liver
type: Class
equivalent class: Class
  intersection of: liver
  intersection of: Restriction
    on property: part of
    some values from: Homo sapiens
subclass of: Mammalia liver
definition: A liver that is a part of or originated from a human (Homo sapiens).
term editor: Priti Parikh
alternative label: human liver
has db xref: FMA:7197

metacyclic promastigote stage
type: Class
subclass of: promastigote stage
subclass of: Trypanosomatida metacyclic stage
subclass of: Restriction
  on property: realizes
  some values from: infectious agent role
definition: A promastigote stage of some kinetoplastids.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: PMID:13129524

Plasmodium falciparum exflagellated microgametocyte stage
type: Class
equivalent class: Class
  intersection of: exflagellated microgametocyte stage
  intersection of: Restriction
    on property: occurs in
    some values from: Anopheles midgut
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: exflagellated microgametocyte stage
subclass of: Plasmodium falciparum lifecycle stage
subclass of: Plasmodium gametocyte stage
definition: An exflagellated microgametocyte stage in the lifecycle of Plasmodium falciparum that occurs in the midgut of a mosquito vector.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: P. falciparum exflagellated microgametocyte stage

Schistosoma haematobium sporocyst stage
type: Class
equivalent class: Class
  intersection of: sporocyst stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma haematobium
subclass of: sporocyst stage
subclass of: Schistosoma haematobium lifecycle stage
definition: A sporocyst stage in the Schistosoma haematobium lifecycle that occurs within the snail intermediate host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium sporocyst stage

Schistosoma japonicum cercaria stage
type: Class
equivalent class: Class
  intersection of: cercaria stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma japonicum
subclass of: cercaria stage
subclass of: Schistosoma japonicum lifecycle stage
definition: A cercaria stage in the lifecycle of Schistosoma japonicum that occurs in a freshwater snail and in fresh water.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. japonicum cercaria stage

Plasmodium falciparum microgametocyte stage
type: Class
equivalent class: Class
  intersection of: microgametocyte stage
  intersection of: Restriction
    on property: occurs in
    some values from: Anopheles midgut
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens erythrocyte
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: Plasmodium falciparum gametocyte stage
subclass of: Plasmodium microgametocyte stage
definition: A microgametocyte stage in the Plasmodium falciparum lifecycle that occurs either in the bloodstream of a human host or the midgut of a mosquito vector.
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: P. Parkh
term editor: S. Khan.
alternative label: P. falciparum microgametocyte stage

Schistosoma haematobium 3 hour schistosomulum
type: Class
subclass of: Schistosoma haematobium schistosomulum
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma haematobium 3 hour schistosomulum stage
subclass of: Restriction
  on property: located in
  some values from: Mammalia skin
definition: A Schistosoma haematobium schistosomulum in a migratory larval form that is found within blood vessels of mammal, as definitive host, 3 hours post-infection.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium 3 hour schistosomulum

Schistosoma haematobium miracidium
type: Class
subclass of: Schistosoma haematobium
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma haematobium miracidium stage
definition: A Schistosoma haematobium in a free-living motile form that is covered with cilia and develops in the snail intermediate host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium miracidium

Schistosoma mansoni 3 day schistosomulum stage
type: Class
equivalent class: Class
  intersection of: 3 day schistosomulum stage
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia lung
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma mansoni
subclass of: Schistosoma mansoni schistosomulum stage
subclass of: 3 day schistosomulum stage
definition: A 3 days schistosomulum stage of Schistosoma mansoni that occurs in the definitive host 3 days post-infection.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: S. mansoni 3 day schistosomulum stage

Phlebotominae proboscis
type: Class
equivalent class: Class
  intersection of: proboscis
  intersection of: Restriction
    on property: part of
    some values from: Phlebotominae
subclass of: proboscis
definition: A proboscis that is a part of or originated from a sand fly of genus Phlebotominae.
term editor: Priti Parikh

Leishmania major promastigote
type: Class
subclass of: Leishmania major
subclass of: Restriction
  on property: participates in
  some values from: Leishmania major promastigote stage
subclass of: Restriction
  on property: located in
  some values from: Phlebotominae proboscis
subclass of: Restriction
  on property: located in
  some values from: Phlebotominae midgut
subclass of: Restriction
  on property: located in
  some values from: Mammalia macrophage
definition: A Leishmania major that is extracellular and motile form with an anterior flagellum. It grows and divides by longitudinal binary fission in the insect vector; i.e., sandfly.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: L. major promastigote
definition source: http://dna.kdna.ucla.edu/parasite_course-old/leish_files/introduction1.htm

3 hour schistosomulum stage
type: Class
subclass of: schistomulum stage
definition: A schistosomulum stage that occurs in 3 hours after infection of the mammalian host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
definition source: PMID:19885392

miracidium stage
type: Class
subclass of: parasite lifecycle stage
subclass of: Restriction
  on property: in taxon
  some values from: parasite organism
definition: A parasite lifecycle stage of Trematodes where the parasite is in free-living motile form, covered with cilia and settles in the mollusc to become a sporocyst.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: Wikipedia: Trematode lifecycle stages

Homo sapiens cerebrospinal fluid
type: Class
equivalent class: Class
  intersection of: cerebrospinal fluid
  intersection of: Restriction
    on property: part of
    some values from: Homo sapiens
subclass of: Mammalia cerebrospinal fluid
definition: Cerebrospinal fluid that is a part of or originated from a human (Homo sapiens).
term editor: Priti Parikh
alternative label: human CSF
alternative label: human cerebral spinal fluid
alternative label: human cerebrospinal fluid
has db xref: FMA:20935

Schistosoma japonicum 3 day schistosomulum
type: Class
subclass of: Schistosoma japonicum schistosomulum
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma japonicum 3 day schistosomulum stage
subclass of: Restriction
  on property: located in
  some values from: Mammalia lung
definition: A Schistosoma japonicum schistosomulum in a migratory larval form that is found within blood vessels of the mammal, as definitive host, 3 days post-infection.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. japonicum 3 day schistosomulum

Schistosoma japonicum 3 hour schistosomulum
type: Class
subclass of: Schistosoma japonicum schistosomulum
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma japonicum 3 hour schistosomulum stage
subclass of: Restriction
  on property: located in
  some values from: Mammalia skin
definition: A Schistosoma japonicum schistosomulum in a migratory larval form that is found within blood vessels of the mammal, as definitive host, 3 weeks post-infection.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. japonicum 3 hour schistosomulum

bloodstream trypomastigote stage
type: Class
subclass of: trypomastigote stage
definition: A trypomastigote stage where trypmastigote form of parasites are found in mammalian host blood stream.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh

Schistosoma japonicum miracidium stage
type: Class
equivalent class: Class
  intersection of: miracidium stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma japonicum
subclass of: miracidium stage
subclass of: Schistosoma japonicum lifecycle stage
definition: A miracidium stage in the Schistosoma japonicum lifecycle that occurs in the intermediate snail host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. japonicum miracidium stage

Schistosoma japonicum daughter sporocyst stage
type: Class
equivalent class: Class
  intersection of: daughter sporocyst stage
  intersection of: Restriction
    on property: occurs in
    some values from: Oncomelania hepatopancreas
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma japonicum
subclass of: daughter sporocyst stage
subclass of: Schistosoma japonicum sporocyst stage
definition: A daughter sporocyst stage of Schistosoma japonicum that occurs in the snail intermediate host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. japonicum daughter sporocyst stage

Schistosoma mansoni 24 hour schistosomulum
type: Class
subclass of: Schistosoma mansoni schistosomulum
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma mansoni 24 hour schistosomulum stage
subclass of: Restriction
  on property: located in
  some values from: Mammalia skin
definition: A Schistosoma mansoni schistosomulum in a migratory larval formi that is found within blood vessels of the definitive host, mammal, 24 hours post-infection.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni 24hour schistosomulum

microgamete stage
type: Class
subclass of: parasite lifecycle stage
subclass of: gamete stage
subclass of: Restriction
  on property: in taxon
  some values from: parasite organism
definition: A gamete stage in apicomplexan parasites when exflagellated microgametocyte divides into microgamete.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Matt Berriman

Homo sapiens skin
type: Class
equivalent class: Class
  intersection of: skin of body
  intersection of: Restriction
    on property: part of
    some values from: Homo sapiens
subclass of: Mammalia skin
definition: A skin that is a part of or originated from a human (Homo sapiens) body.
term editor: Priti Parikh
alternative label: human skin
has db xref: FMA:7163

macrogametocyte stage
type: Class
subclass of: gametocyte stage
definition: A gametocyte stage where a cell differentiates into a female sexual form called macrogametocyte.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh

Schistosoma haematobium 24 hour schistosomulum
type: Class
subclass of: Schistosoma haematobium schistosomulum
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma haematobium 24 hour schistosomulum stage
subclass of: Restriction
  on property: located in
  some values from: Mammalia skin
definition: A Schistosoma haematobium schistosomulum in a migratory larval form that is found within blood vessels of mammal, as definitive host, 24 hours post-infection.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium 24 hour schistosomulum

Schistosoma japonicum daughter sporocyst
type: Class
subclass of: Schistosoma japonicum sporocyst
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma japonicum daughter sporocyst stage
subclass of: Restriction
  on property: located in
  some values from: Oncomelania hepatopancreas
definition: A Schistosoma japonicum sporocyst that develops into cercariae.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. japonicum daughter sporocyst

Trypanosoma brucei procyclic trypomastigote
type: Class
subclass of: Trypanosoma brucei trypomastigote
subclass of: Restriction
  on property: participates in
  some values from: Trypanosoma brucei procyclic trypomastigote stage
subclass of: Restriction
  on property: located in
  some values from: Glossina midgut
definition: A Trypanosoma brucei trypomastigote that is a dividing form of Trypanosoma brucei found in the midgut of an insect vector.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: T. brucei procyclic trypomastigote

Anopheles midgut
type: Class
equivalent class: Class
  intersection of: midgut
  intersection of: Restriction
    on property: part of
    some values from: Anopheles <genus>
subclass of: midgut
definition: A midgut that is a part of or originated from an Anopheles mosquito.
term editor: Jie Zheng

trypomastigote stage
type: Class
subclass of: parasite lifecycle stage
subclass of: Restriction
  on property: in taxon
  some values from: Trypanosoma
definition: A parasite lifecycle stage of trypanosomes. In trypomastigote stage, the kinetoplast is near the posterior end of the body, and the flagellum lies attached to the cell body for most of its length by an undulating membrane.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: Wikipedia: Trypanosomatid

Trypanosoma brucei metacyclic trypomastigote
type: Class
subclass of: Trypanosoma brucei trypomastigote
subclass of: Restriction
  on property: participates in
  some values from: Trypanosoma brucei metacyclic trypomastigote stage
subclass of: Restriction
  on property: located in
  some values from: Glossina salivary gland
subclass of: Restriction
  on property: located in
  some values from: Mammalia blood
definition: A Trypanosoma brucei trypomastigote that is a non-dividing form infectious for the mammal host. It is found in the salivary gland of an insect vector or blood of a mammal host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: T. brucei metacyclic trypomastigote
definition source: http://dna.kdna.ucla.edu/parasite_course-old/african%20tryps%20new_files/subchapters/Life%20cycle.htm

Plasmodium falciparum erythrocytic schizont stage
type: Class
equivalent class: Class
  intersection of: erythrocytic schizont stage
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens erythrocyte
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: Plasmodium falciparum lifecycle stage
subclass of: Plasmodium erythrocytic schizont stage
definition: An erythrocytic schizont stage in the Plasmodium falciparum lifecycle that occurs in the infected erythrocytes of a human host.
editor note: updated according to OPL terms Plasmodium final excel file from C. Janse, S. Khan
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parkh
term editor: S. Khan
alternative label: P. falciparum erythorcytic schizont stage

merozoite stage
type: Class
subclass of: parasite lifecycle stage
subclass of: Restriction
  on property: in taxon
  some values from: parasite organism
definition: A parasite lifecycle stage of apicomplexan species where a daughter cell, called merozoite is produced from schizont through schizogony.
editor note: adjusted to be more general
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: http://www.biology.ualberta.ca/parasites/parpub/text/text/glossarM.htm

Schistosoma haematobium worm
type: Class
subclass of: Schistosoma haematobium
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma haematobium worm stage
definition: A Schistosoma haematobium is a mature form of Schistosoma haematobium and capable of sexual reproduction, which lives in the pelvic blood vessels of the vesicle plexis of the mammal host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium worm

Schistosoma mansoni schistosomulum
type: Class
subclass of: Schistosoma mansoni
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma mansoni schistosomulum stage
definition: A Schistosoma mansoni in a migratory larval form that is found within blood vessels of the definitive host, mammal, and develops into the worm.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni schistosomulum

Schistosoma japonicum 6 day schistosomulum
type: Class
subclass of: Schistosoma japonicum schistosomulum
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma japonicum 6 day schistosomulum stage
subclass of: Restriction
  on property: located in
  some values from: Mammalia lung
definition: A Schistosoma japonicum schistosomulum in a migratory larval form that is found within blood vessels of the mammal, as definitive host, 6 days post-infection.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. japonicum 6 day schistosomulum

Homo sapiens hepatocyte
type: Class
equivalent class: Class
  intersection of: hepatocyte
  intersection of: Restriction
    on property: part of
    some values from: Homo sapiens
subclass of: Vertebrate hepatocyte
definition: A hepatocyte that is a part of or originated from a human (Homo sapiens).
term editor: Priti Parikh
alternative label: human hepatocyte
has db xref: FMA:14515

Schistosoma mansoni sporocyst stage
type: Class
equivalent class: Class
  intersection of: sporocyst stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma mansoni
subclass of: sporocyst stage
subclass of: Schistosoma mansoni lifecycle stage
definition: A sporocyst stage in the Schistosoma mansoni lifecycle that occurs in the snail intermediate host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni sporocyst stage

Plasmodium falciparum erythrocytic ring trophozoite stage
type: Class
equivalent class: Class
  intersection of: erythrocytic ring trophozoite stage
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: Plasmodium falciparum lifecycle stage
subclass of: Plasmodium erythrocytic ring trophozoite stage
definition: An erythrocytic ring trophozoite stage in the Plasmodium falciparum life cycle that occurs in erythrocytes of a human host. During this stage some Plasmodium falciparum merozoites undergo asexual reproduction cycle in erythrocytes and form young trophozoites that are referred to as "ring form" due to their morphology.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: P. falciparum erythrocytic ring trophozoite stage
definition source: Wikipedia: Plasmodium falciparum biology

Schistosoma japonicum cercaria
type: Class
subclass of: Schistosoma japonicum
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma japonicum cercaria stage
definition: A Schistosoma japonicum in a parasitic larval form that develops in a freshwater snail and is released into the water.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. japonicum cercaria

procyclic promastigote stage
type: Class
subclass of: promastigote stage
subclass of: Trypanosomatida procyclic stage
subclass of: Restriction
  on property: has part
  some values from: cell division
subclass of: Restriction
  on property: occurs in
  some values from: Class
    union of: Phlebotominae midgut
    union of: Glossina midgut
definition: A promastigote stage where the form of parasite is short, ovoid, and slightly motile.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: PMID:13129524

Schistosoma mansoni 6 day schistosomulum stage
type: Class
equivalent class: Class
  intersection of: 6 day schistosomulum stage
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia lung
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma mansoni
subclass of: 6 day schistosomulum stage
subclass of: Schistosoma mansoni schistosomulum stage
definition: A 6 day schistosomulum stage of Schistosoma mansoni that occurs in the definitive host 6 days post-infection.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni 6 day schistosomulum stage

Schistosoma japonicum 6 day schistosomulum stage
type: Class
equivalent class: Class
  intersection of: Schistosoma japonicum schistosomulum stage
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia lung
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma japonicum
subclass of: Schistosoma japonicum schistosomulum stage
definition: A schistosoma japonicum schistosomulum stage that occurs in the definitive host 6 days post-infection.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. japonicum 6 day schistosomulum stage

Homo sapiens mesenteric vein
type: Class
equivalent class: Class
  intersection of: mesenteric vein
  intersection of: Restriction
    on property: part of
    some values from: Homo sapiens
subclass of: Mammalia mesenteric vein
definition: A mesenteric vein that is a part of or originated from a human (Homo sapiens).
term editor: Priti Parikh
alternative label: human mesenteric vein

Trypanosoma brucei lifecycle stage
type: Class
equivalent class: Class
  intersection of: parasite lifecycle stage
  intersection of: Restriction
    on property: in taxon
    some values from: Trypanosoma brucei
subclass of: parasite lifecycle stage
definition: A lifecycle stage of Trypanosoma brucei.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: T. brucei lifecycle stage

Trypanosoma cruzi epimastigote
type: Class
subclass of: Trypanosoma cruzi
subclass of: Restriction
  on property: participates in
  some values from: Trypanosoma cruzi epimastigote stage
subclass of: Restriction
  on property: located in
  some values from: Triatominae midgut
definition: A Trypanosoma cruzi that is found in the intestinal tract of the insect vector. In this form, the kinetoplast is found anterior and adjacent to the nucleus. The flagellum emerges in the middle of the cell.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: T. cruzi epimastigote
definition source: http://dna.kdna.ucla.edu/parasite_course-old/cruzi_files/intro.htm

Plasmodium falciparum microgametocyte
type: Class
subclass of: Plasmodium falciparum gametocyte
subclass of: Plasmodium microgametocyte
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium falciparum microgametocyte stage
subclass of: Restriction
  on property: located in
  some values from: Anopheles midgut
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens erythrocyte
definition: A Plasmodium falciparum gametocyte that is a male gametocyte and found in either bloodstream of a human host or midgut of a mosquito vector. The microgametocyte is a precursor cell of the microgamete.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: P. falciparum microgametocyte

Schistosoma japonicum 7 week worm
type: Class
subclass of: Schistosoma japonicum worm
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma japonicum 7 week worm stage
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens mesenteric vein
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens intestine
definition: A Schistosoma japonicum worm is the mature form of Schistosoma japonicum and capable of sexual reproduction, which is found in the small superior mesenteric blood vessels associated with the ileo-caecal area of the intestine of the human host 7 weeks after infection of the mammal host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: S. japonicum 7 week worm

Schistosoma japonicum egg
type: Class
subclass of: Schistosoma japonicum
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma japonicum egg stage
definition: A Schistosoma japonicum in an egg form that is laid by the female adult worm and released into the host gut where they leave the host in the faeces.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. japonicum egg

Schistosoma japonicum 3 week worm
type: Class
subclass of: Schistosoma japonicum worm
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma japonicum 3 week worm stage
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens mesenteric vein
definition: A Schistosoma japonicum worm is capable of sexual reproduction, which is found in the small superior mesenteric blood vessels associated with the ileo-caecal area of the intestine of the mammal host 3 weeks after infection of the human host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: S. japonicum 3 week worm

Trypanosoma brucei metacyclic trypomastigote stage
type: Class
equivalent class: Class
  intersection of: metacyclic trypomastigote stage
  intersection of: Restriction
    on property: occurs in
    some values from: Glossina salivary gland
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia blood
  intersection of: Restriction
    on property: in taxon
    some values from: Trypanosoma brucei
subclass of: Trypanosoma brucei lifecycle stage
subclass of: metacyclic trypomastigote stage
definition: A metacyclic trypomastigote stage in the lifecycle of Trypanosoma brucei that occurs either in vertebrate host bloodstream or in salivary glands of an insect vector.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: T. brucei metacyclic trypomastigote stage

trophozoite stage
type: Class
subclass of: parasite lifecycle stage
subclass of: Restriction
  on property: in taxon
  some values from: parasite organism
definition: A parasite lifecycle stage of some protozoan parasites that is a non-reproductive, feeding and growing stage.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: http://www.biology.ualberta.ca/parasites/parpub/text/text/glossarT.htm

Leishmania major procyclic promastigote stage
type: Class
equivalent class: Class
  intersection of: procyclic promastigote stage
  intersection of: Restriction
    on property: occurs in
    some values from: Phlebotominae midgut
  intersection of: Restriction
    on property: in taxon
    some values from: Leishmania major
subclass of: procyclic promastigote stage
subclass of: Leishmania major lifecycle stage
definition: A procyclic promastigote stage in the Leishmania major lifecycle.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: L. major procyclic promastigote stage

hepatic schizont stage
type: Class
subclass of: schizont stage
definition: A schizont stage that occurs in hepatocyte where sporozoites mature into a schizont.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Matt Berriman
term editor: Priti Parikh
definition source: PMID:11006474

Plasmodium falciparum schizont
type: Class
subclass of: Plasmodium falciparum
subclass of: Plasmodium schizont
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium falciparum schizont stage
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens hepatocyte
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens erythrocyte
definition: A Plasmodium falciparum divides through schizogony. Depending on its location, it is either called hepatic or erythrocytic schizont. The schizont is a dividing stage with 2 or more nuclei.
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parkh
term editor: S. Khan
alternative label: P. falciparum schizont

Trypanosoma cruzi amastigote
type: Class
subclass of: Trypanosoma cruzi
subclass of: Restriction
  on property: participates in
  some values from: Trypanosoma cruzi amastigote stage
subclass of: Restriction
  on property: located in
  some values from: Mammalia macrophage
definition: A Trypanosoma cruzi that is the intracellular dividing form in the cytoplasm of mammalian cells. It is a round/oval-shaped cell with no protruding flagellum.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: T. cruzi amastigote
definition source: http://dna.kdna.ucla.edu/parasite_course-old/cruzi_files/intro.htm

Schistosoma haematobium 3 day schistosomulum stage
type: Class
equivalent class: Class
  intersection of: 3 day schistosomulum stage
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia liver
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma haematobium
subclass of: Schistosoma haematobium schistosomulum stage
subclass of: 3 day schistosomulum stage
definition: A 3 days schistosomulum stage of Schistosoma haematobium occurs in the definitive host 3 days post-infection.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: S. haematobium 3 day schistosomulum stage

Schistosoma mansoni 24 hour schistosomulum stage
type: Class
equivalent class: Class
  intersection of: 24 hour schistosomulum stage
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia skin
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma mansoni
subclass of: Schistosoma mansoni schistosomulum stage
subclass of: 24 hour schistosomulum stage
definition: A 24 hours schistosomulum stage of Schistosoma mansoni that occurs in the definitive host 24 hours post-infection.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: S. mansoni 24 hour schistosomulum stage

Trypanosoma cruzi amastigote stage
type: Class
equivalent class: Class
  intersection of: amastigote stage
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia macrophage
  intersection of: Restriction
    on property: in taxon
    some values from: Trypanosoma cruzi
subclass of: amastigote stage
subclass of: Trypanosoma cruzi lifecycle stage
definition: An amastigote stage in the lifecycle of Trypanosoma cruzi that occurs in mammalian hosts.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: T. cruzi amastigote stage

6 day schistosomulum stage
type: Class
subclass of: schistomulum stage
definition: A schistosomulum stage that occurs in 6 days after infection of the mammalian host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: PMID:19885392

Schistosoma mansoni 3 hour schistosomulum
type: Class
subclass of: Schistosoma mansoni schistosomulum
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma mansoni 3 hour schistosomulum stage
subclass of: Restriction
  on property: located in
  some values from: Mammalia skin
definition: A Schistosoma mansoni schistosomulum in a migratory larval formi that is found within blood vessels of the definitive host, mammal, 3 hours post-infection.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni 3hour schistosomulum

Plasmodium falciparum macrogametocyte stage
type: Class
equivalent class: Class
  intersection of: macrogametocyte stage
  intersection of: Restriction
    on property: occurs in
    some values from: Anopheles midgut
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens erythrocyte
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: Plasmodium falciparum gametocyte stage
subclass of: Plasmodium macrogametocyte stage
definition: A macrogametocyte stage in the Plasmodium falciparum lifecycle that occurs either in the bloodstream of a human host or the midgut of a mosquito vector.
editor note: gametocytes are mainly found in the blood
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
term editor: S. Khan
alternative label: P. falciparum macrogametocyte stage

Schistosoma haematobium miracidium stage
type: Class
equivalent class: Class
  intersection of: miracidium stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma haematobium
subclass of: miracidium stage
subclass of: Schistosoma haematobium lifecycle stage
definition: A miracidium stage in the Schistosoma haematobium lifecycle that occurs in the intermediate snail host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium miracidium stage

cercaria stage
type: Class
subclass of: parasite lifecycle stage
subclass of: Restriction
  on property: in taxon
  some values from: parasite organism
definition: A parasite lifecycle stage that is a free-living larval stage of Digenea, developed within the germinal cells of the sporocyst or redia. A cercaria has a tapering head with large penetration glands. It may or may not have a long swimming "tail", depending on the species. The motile cercaria finds and settles in a host where it will become either an adult, or a mesocercaria, or a metacercaria, according to species.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: Wikipedia: Trematode lifecycle stages

Schistosoma japonicum worm stage
type: Class
equivalent class: Class
  intersection of: parasitic worm stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma japonicum
subclass of: parasitic worm stage
subclass of: Schistosoma japonicum lifecycle stage
definition: A worm stage of Schistosoma japonicum that is fully developed mature form and found in the small superior mesenteric blood vessels associated with the ileo-caecal area of the intestine of the mammalian host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. japonicum worm stage

Schistosoma japonicum egg stage
type: Class
equivalent class: Class
  intersection of: egg stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma japonicum
subclass of: Schistosoma japonicum lifecycle stage
subclass of: egg stage
definition: An egg stage in the lifecycle of Schistosoma japonicum that occurs in the mammalian host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. japonicum egg stage

oocyst stage
type: Class
subclass of: parasite lifecycle stage
subclass of: Restriction
  on property: in taxon
  some values from: parasite organism
definition: A parasite lifecycle stage of sporozoa consisting of a zygote enclosed by cyst wall.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: Mosby's Medical Dictionary, 8th edition. � 2009, Elsevier. (http://medical-dictionary.thefreedictionary.com/oocyst)

Schistosoma haematobium 3 hour schistosomulum stage
type: Class
equivalent class: Class
  intersection of: 3 hour schistosomulum stage
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia skin
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma haematobium
subclass of: 3 hour schistosomulum stage
subclass of: Schistosoma haematobium schistosomulum stage
definition: A 3 hours schistosomulum stage of Schistosoma haematobium that occurs in the definitive host 3 hours post-infection.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium 3 hour schistosomulum stage

Plasmodium falciparum macrogamete stage
type: Class
equivalent class: Class
  intersection of: macrogamete stage
  intersection of: Restriction
    on property: occurs in
    some values from: Anopheles midgut
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: Plasmodium falciparum gamete stage
subclass of: Plasmodium macrogamete stage
definition: A macrogamete stage in the Plasmodium falciparum lifecycle that occurs in the midgut of a mosquito vector.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: P. falciparum macrogamete stage

procyclic trypomastigote stage
type: Class
subclass of: trypomastigote stage
subclass of: Trypanosomatida procyclic stage
subclass of: Restriction
  on property: has part
  some values from: cell division
subclass of: Restriction
  on property: occurs in
  some values from: Class
    union of: Phlebotominae midgut
    union of: Glossina midgut
definition: A trypomastigote stage where trypomastigote form of parasites are in dividing form. This stage occurs in fly vector.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh

Schistosoma japonicum schistosomulum
type: Class
subclass of: Schistosoma japonicum
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma japonicum schistosomulum stage
definition: A Schistosoma japonicum in a migratory larval form that is found within blood vessels of the definitive host and develops into the worm.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. japonicum schistosomulum

erythrocytic schizont stage
type: Class
subclass of: schizont stage
definition: A schizont stage that occurs in erythrocytes where trophozoites mature into a schizont and schizont produces daughter trophozoites or merozoites.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Matt Berriman
term editor: Priti Parikh
definition source: PMID: 11006474

Schistosoma haematobium cercaria
type: Class
subclass of: Schistosoma haematobium
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma haematobium cercaria stage
definition: A Schistosoma haematobium is the parasitic larval form of the Schistosoma haematobium that develops in a freshwater snail and is released into the water.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium cercaria

parasite lifecycle in host liver stage
type: Class
subclass of: parasite lifecycle stage
subclass of: Restriction
  on property: occurs in
  some values from: liver
subclass of: Restriction
  on property: in taxon
  some values from: parasite organism
definition: A parasite lifecycle stage that occurs in the liver of the host organism. For Plasmodium species these stages can include sporozoites, trophozoites, schizonts, and merozoites.
term editor: Chris Stoeckert
alternative label: liver stage
definition source: EuPathDB

Trypanosoma brucei procyclic trypomastigote stage
type: Class
equivalent class: Class
  intersection of: procyclic promastigote stage
  intersection of: Restriction
    on property: occurs in
    some values from: Glossina midgut
  intersection of: Restriction
    on property: in taxon
    some values from: Trypanosoma brucei
subclass of: procyclic promastigote stage
subclass of: Trypanosoma brucei lifecycle stage
definition: A procyclic promastigote stage in the Trypanosoma brucei lifecycle.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh

parasitic worm stage
type: Class
subclass of: parasite lifecycle stage
subclass of: Restriction
  on property: in taxon
  some values from: parasite organism
definition: A parasite lifecycle stage of some parasites in which the parasite develops into a worm form, and undergoes maturation.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: http://www.path.cam.ac.uk/~schisto/schistosoma/schisto_lifecycle_egg.html

Bulinus hepatopancreas
type: Class
equivalent class: Class
  intersection of: hepatopancreas
  intersection of: Restriction
    on property: part of
    some values from: Bulinus
subclass of: hepatopancreas
definition: Hepatopancreas that is a part of or originated from a Bulinus snail.
term editor: Priti Parikh

schizont stage
type: Class
subclass of: parasite lifecycle stage
subclass of: Restriction
  on property: in taxon
  some values from: parasite organism
definition: A parasite lifecycle stage that is the multinucleate stage in the development of some members of the Sarcodina and some sporozoans during schizogony.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: http://medical-dictionary.thefreedictionary.com/schizont

macrogamete stage
type: Class
subclass of: parasite lifecycle stage
subclass of: gamete stage
subclass of: Restriction
  on property: in taxon
  some values from: parasite organism
definition: A gamete stage in parasites when macrogametocytes produce macrogametes through the process known as gametogenesis.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: http://www.tulane.edu/~wiser/malaria/mal_lc.PDF

daughter sporocyst stage
type: Class
subclass of: sporocyst stage
definition: A sporocyst stage of Trematodes produced by a mother sporocyst; it lacks a gut and is capable of asexual production of either rediae or cercariae.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: http://www.biology.ualberta.ca/parasites/parpub/text/text/glossarD.htm

Schistosoma haematobium 7 week worm
type: Class
subclass of: Schistosoma haematobium worm
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma haematobium 7 week worm stage
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens vesical venus plexus
definition: A Schistosoma haematobium worm is the mature form of Schistosoma haematobium and capable of sexual reproduction, which is found in the pelvic blood vessels of the vesicle plexis of the mammal host 7 weeks after infection of the mammal host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium 7 week worm

Triatominae midgut
type: Class
equivalent class: Class
  intersection of: midgut
  intersection of: Restriction
    on property: part of
    some values from: Triatominae
subclass of: midgut
definition: A midgut that is a part of or originated from a Triatominae bug.
term editor: Priti Parikh

Plasmodium falciparum ookinete
type: Class
subclass of: Plasmodium falciparum
subclass of: Plasmodium ookinete
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium falciparum ookinete stage
subclass of: Restriction
  on property: located in
  some values from: Anopheles midgut
definition: A Plasmodium falciparum that is a 'banana-shaped' form and originates from the round zygote. The ookinete is found in the midgut of a mosquito vector and traverses the midgut wall of a mosquito vector.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: P. falciparum ookinete
definition source: Wikipedia: Plasmodium falciparum biology

Schistosoma mansoni 3 week worm
type: Class
subclass of: Schistosoma mansoni worm
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma mansoni 3 week worm stage
subclass of: Restriction
  on property: located in
  some values from: Mammalia mesenteric vein
definition: A Schistosoma mansoni worm that is capable of sexual reproduction, which is found in the small inferior mesenteric blood vessels surrounding the large intestine of the mammal host 3 weeks after infection of the mammalian host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni 3 week worm

Schistosoma haematobium worm stage
type: Class
equivalent class: Class
  intersection of: parasitic worm stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma haematobium
subclass of: parasitic worm stage
subclass of: Schistosoma haematobium lifecycle stage
definition: A worm stage of Schistosoma haematobium that is fully developed mature form and found in the pelvic blood vessels of the vesicle plexis of the mammalian host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium worm stage

Trypanosoma brucei epimastigote
type: Class
subclass of: Trypanosoma brucei
subclass of: Restriction
  on property: participates in
  some values from: Trypanosoma brucei epimastigote stage
subclass of: Restriction
  on property: located in
  some values from: Glossina salivary gland
definition: A Trypanosoma brucei that is found in the salivary glands of tse-tse fly. In this form the kinetoplast is anterior to the nucleus with a short undulating membrane running about half the length of the body.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: T. brucei epimastigote
definition source: http://dna.kdna.ucla.edu/parasite_course-old/african%20tryps%20new_files/contents1.htm

Plasmodium falciparum hepatic schizont stage
type: Class
equivalent class: Class
  intersection of: hepatic schizont stage
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens hepatocyte
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: Plasmodium falciparum lifecycle stage
subclass of: Plasmodium hepatic schizont stage
definition: A hepatic schizont stage in the lifecycle of Plasmodium falciparum that occurs in the infected hepatocytes of a human host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: P. falciparum hepatic schizont stage

Schistosoma japonicum sporocyst
type: Class
subclass of: Schistosoma japonicum
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma japonicum sporocyst stage
definition: A Schistosoma japonicum is an elongated sac that develops from the miracidium within the snail indermediate host, and that either produces more sporocysts or develops into cercariae.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. japonicum sporocyst

schistomulum stage
type: Class
subclass of: parasite lifecycle stage
subclass of: Restriction
  on property: in taxon
  some values from: parasite organism
definition: A parasite lifecycle stage that is the migratory stage between cercaria and adult of the schistosomes; equivalent to the metacercarial stage in other digeneans.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: http://www.biology.ualberta.ca/parasites/parpub/text/text/glossarS.htm

Homo sapiens erythrocyte
type: Class
equivalent class: Class
  intersection of: erythrocyte
  intersection of: Restriction
    on property: part of
    some values from: Homo sapiens
subclass of: Vertebrate erythrocyte
definition: An erythrocyte that is a part of or originated from a human (Homo sapiens).
term editor: Priti Parikh
alternative label: human RBC
alternative label: human erythrocyte
alternative label: human red blood cell
has db xref: FMA:62845

Homo sapiens vesical venus plexus
type: Class
equivalent class: Class
  intersection of: vesical venus plexus
  intersection of: Restriction
    on property: part of
    some values from: Homo sapiens
subclass of: vesical venus plexus
definition: Vesical venus plexus that is a part of or originated from a human (Homo sapiens).
term editor: Priti Parikh
alternative label: human vesical venus plexus
has db xref: FMA:18934

sporocyst stage
type: Class
subclass of: parasite lifecycle stage
subclass of: Restriction
  on property: in taxon
  some values from: parasite organism
definition: A parasite lifecycle stage that is the early developmental stage capable of asexual reproduction: in sporozoans it is usually enclosed within an oocyst; in digeneans it is an intramolluscan stage lacking a gut.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: http://www.biology.ualberta.ca/parasites/parpub/text/text/glossarD.htm

Schistosoma haematobium 3 week worm
type: Class
subclass of: Schistosoma haematobium worm
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma haematobium 3 week worm stage
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens urinary bladder
definition: A Schistosoma haematobium worm is the mature form of Schistosoma haematobium and capable of sexual reproduction, which is found in the pelvic blood vessels of the vesicle plexis of the human host 3 weeks after infection of the mammal host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium 3 week worm

Schistosoma mansoni schistosomulum stage
type: Class
equivalent class: Class
  intersection of: schistomulum stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma mansoni
subclass of: schistomulum stage
subclass of: Schistosoma mansoni lifecycle stage
definition: A schistosomulum stage of Schistosoma mansoni that occurs in the definitive host and is followed by the parasitic worm stage.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni schistosomulum stage

Schistosoma haematobium cercaria stage
type: Class
equivalent class: Class
  intersection of: cercaria stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma haematobium
subclass of: cercaria stage
subclass of: Schistosoma haematobium lifecycle stage
definition: A cercaria stage in the lifecycle of Schistosoma haematobium that occurs in a freshwater snail and in fresh water.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium cercaria stage

Leishmania major metacyclic promastigote stage
type: Class
equivalent class: Class
  intersection of: metacyclic promastigote stage
  intersection of: Restriction
    on property: occurs in
    some values from: Phlebotominae proboscis
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia macrophage
  intersection of: Restriction
    on property: in taxon
    some values from: Leishmania major
subclass of: metacyclic promastigote stage
subclass of: Leishmania major lifecycle stage
definition: A metacyclic promastigote stage in the lifecycle of Leishmania major.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: L. major metacyclic promastigote stage

Plasmodium falciparum merozoite stage
type: Class
equivalent class: Class
  intersection of: merozoite stage
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens erythrocyte
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: Plasmodium falciparum lifecycle stage
subclass of: Plasmodium merozoite stage
definition: A merozoite stage in the Plasmodium falciparum lifecycle that occurs in the bloodstream or hepatocytes of a human host.
term editor: Chris Stoeckert
term editor: Priti Parikh
alternative label: P. falciparum merozoite stage

Biomphalaria hepatopancreas
type: Class
equivalent class: Class
  intersection of: hepatopancreas
  intersection of: Restriction
    on property: part of
    some values from: Biomphalaria
subclass of: hepatopancreas
definition: Hepatopancreas that is a part of or originated from a Biomphalaria snail.
term editor: Priti Parikh

Schistosoma mansoni egg
type: Class
subclass of: Schistosoma mansoni
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma mansoni egg stage
definition: A Schistosoma mansoni in an egg form that is laid by the female adult worm and released into the host gut where they leave the host in the faeces.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni egg

Schistosoma japonicum 3 week worm stage
type: Class
equivalent class: Class
  intersection of: 3 week parasitic worm stage
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens mesenteric vein
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma japonicum
subclass of: Schistosoma japonicum worm stage
subclass of: 3 week parasitic worm stage
definition: A worm stage of Schistosoma japonicum that is found in the small superior mesenteric blood vessels associated with the ileo-caecal area of the intestine of the definitive host 3 weeks after infection.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: S. japonicum 3 week worm stage

Schistosoma mansoni 3 week worm stage
type: Class
equivalent class: Class
  intersection of: 3 week parasitic worm stage
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia mesenteric vein
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma mansoni
subclass of: 3 week parasitic worm stage
subclass of: Schistosoma mansoni worm stage
definition: A worm stage of Schistosoma mansoni that is found in the small inferior mesenteric blood vessels surrounding the large intestine of the definitive host 3 weeks after infection.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: S. mansoni 3 week worm stage

epimastigote stage
type: Class
subclass of: parasite lifecycle stage
subclass of: Restriction
  on property: in taxon
  some values from: parasite organism
definition: A parasite lifecycle stage of Trypanosomatids. During this stage, the undulating membrane is shortened and the flagellar pocket and the kinetoplast are anterior to the nucleus. This stage occurs in the insect host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh

Schistosoma haematobium daughter sporocyst
type: Class
subclass of: Schistosoma haematobium sporocyst
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma haematobium daughter sporocyst stage
subclass of: Restriction
  on property: located in
  some values from: Bulinus hepatopancreas
definition: A Schistosoma haematobium sporocyst that develops into cercariae.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium daughter sporocyst

Plasmodium falciparum erythrocytic schizont
type: Class
subclass of: Plasmodium falciparum schizont
subclass of: Plasmodium erythrocytic schizont
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium falciparum erythrocytic schizont stage
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens erythrocyte
definition: A Plasmodium falciparum schizont that is found in infected erythrocytes of a human host.
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parkh
term editor: S. Khan
alternative label: P. falciparum erythrocytic schizont

Schistosoma haematobium 7 week worm stage
type: Class
equivalent class: Class
  intersection of: 7 week parasitic worm stage
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens vesical venus plexus
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma haematobium
subclass of: Schistosoma haematobium worm stage
subclass of: 7 week parasitic worm stage
definition: A 7 week worm stage of Schistosoma haematobium that is the mature stage of Schistosoma haematobium and found in the pelvic blood vessels of the vesicle plexis of the definitive host 7 weeks after weeks after infection .
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: S. haematobium 7 week worm stage

Schistosoma mansoni miracidium stage
type: Class
equivalent class: Class
  intersection of: miracidium stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma mansoni
subclass of: miracidium stage
subclass of: Schistosoma mansoni lifecycle stage
definition: A miracidium stage in the Schistosoma mansoni lifecycle that occurs in the intermediate snail host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni miracidium stage

Plasmodium falciparum oocyst stage
type: Class
equivalent class: Class
  intersection of: oocyst stage
  intersection of: Restriction
    on property: occurs in
    some values from: Anopheles midgut
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: Plasmodium falciparum lifecycle stage
subclass of: Plasmodium oocyst stage
definition: An oocyst stage in the Plasmodium falciparum lifecycle that occurs on the hemocoel side of the midgut of a mosquito vector. During this stage Plasmodium falciparum ookinete invades and escapes midgut wall of mosquito and embed itself onto the exterior of the gut membrane and develop encysted zygote, called oocyst.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: P. falciparum oocyst stage

amastigote stage
type: Class
subclass of: parasite lifecycle stage
subclass of: Restriction
  on property: in taxon
  some values from: parasite organism
definition: A parasite lifecycle stage is a nonflagellate intracellular developmental stage in the trypanosomatid parasites lifecycle that occurs in mammalian host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh

Plasmodium falciparum sporozoite stage
type: Class
equivalent class: Class
  intersection of: sporozoite stage
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens hepatocyte
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens blood
  intersection of: Restriction
    on property: occurs in
    some values from: Anopheles salivary gland
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: Plasmodium falciparum lifecycle stage
subclass of: Plasmodium sporozoite stage
definition: A sporozoite stage in the Plasmodium falciparum lifecycle that occurs in the salivary glands of the mosquito and invades hepatocytes in the human host.
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Matt Berrimen
term editor: Priti Parikh
term editor: S. Khan
alternative label: P. falciparum sporozoite stage

Trypanosoma cruzi metacyclic trypomastigote
type: Class
subclass of: Trypanosoma cruzi trypomastigote
subclass of: Restriction
  on property: participates in
  some values from: Trypanosoma cruzi metacyclic trypomastigote stage
subclass of: Restriction
  on property: located in
  some values from: Mammalia blood
subclass of: Restriction
  on property: located in
  some values from: Mammalia macrophage
definition: A Trypanosoma cruzi trypomastigote that is found in blood or cells of mammal hosts at the infectious stage for mammals.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: T. cruzi metacyclic trypomastigote
definition source: http://dna.kdna.ucla.edu/parasite_course-old/cruzi_files/intro.htm

Homo sapiens blood
type: Class
equivalent class: Class
  intersection of: blood
  intersection of: Restriction
    on property: part of
    some values from: Homo sapiens
subclass of: Mammalia blood
definition: Blood that is part of or originated from a human (Homo sapiens).
editor note: previous def was: blood of human
term editor: Chris Stoeckert
alternative label: human blood
definition source: OPL

Schistosoma japonicum schistosomulum stage
type: Class
equivalent class: Class
  intersection of: schistomulum stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma japonicum
subclass of: schistomulum stage
subclass of: Schistosoma japonicum lifecycle stage
definition: A schistosomulum stage of Schistosoma japonicum that occurs in the definitive host and is followed by the parasitic worm stage.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. japonicum schistosomulum stage

exflagellated microgametocyte stage
type: Class
subclass of: microgametocyte stage
definition: A microgametocyte stage in some apicomplexan parasites where microgametocyte gets matured and form microgamete through the process known as exflagellation.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh

Schistosoma mansoni 3 hour schistosomulum stage
type: Class
equivalent class: Class
  intersection of: 3 hour schistosomulum stage
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia skin
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma mansoni
subclass of: 3 hour schistosomulum stage
subclass of: Schistosoma mansoni schistosomulum stage
definition: A 3 hours schistosomulum stage of Schistosoma mansoni that occurs in the definitive host 3 hours post-infection.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni 3 hour schistosomulum stage

Anopheles salivary gland
type: Class
equivalent class: Class
  intersection of: saliva-secreting gland
  intersection of: Restriction
    on property: part of
    some values from: Anopheles <genus>
subclass of: saliva-secreting gland
definition: A salivary gland that is a part of or originated from an Anopheles mosquito.
term editor: Priti Parikh

Homo sapiens macrophage
type: Class
equivalent class: Class
  intersection of: macrophage
  intersection of: Restriction
    on property: part of
    some values from: Homo sapiens
subclass of: Mammalia macrophage
definition: A macrophage that is a part of or originated from a human (Homo sapiens).
term editor: Jie Zheng
alternative label: human macrophage
has db xref: FMA:63261

Schistosoma mansoni 3 day schistosomulum
type: Class
subclass of: Schistosoma mansoni schistosomulum
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma mansoni 3 day schistosomulum stage
subclass of: Restriction
  on property: located in
  some values from: Mammalia lung
definition: A Schistosoma mansoni schistosomulum in a migratory larval formi that is found within blood vessels of the definitive host, mammal, 3 days post-infection.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni 3day schistosomulum

Schistosoma haematobium 6 day schistosomulum stage
type: Class
equivalent class: Class
  intersection of: 6 day schistosomulum stage
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia liver
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma haematobium
subclass of: 6 day schistosomulum stage
subclass of: Schistosoma haematobium schistosomulum stage
definition: A 6 day schistosomulum stage of Schistosoma haematobium that occurs in the definitive host 6 days post-infection.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium 6 day schistosomulum stage

Schistosoma haematobium egg stage
type: Class
equivalent class: Class
  intersection of: egg stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma haematobium
subclass of: Schistosoma haematobium lifecycle stage
subclass of: egg stage
definition: An egg stage in the lifecycle of Schistosoma haematobium that occurs in the mammalian host..
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium egg stage

Schistosoma japonicum worm
type: Class
subclass of: Schistosoma japonicum
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma japonicum worm stage
definition: A Schistosoma japonicum is the mature form of Schistosoma japonicum and capable of sexual reproduction, which lives in the small superior mesenteric blood vessels associated with the ileo-caecal area of the intestine of the mammal host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. japonicum worm

adult female parasitic worm stage
type: Class
subclass of: adult parasitic worm stage
definition: An adult worm stage of a female parasitic worm.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: http://www.path.cam.ac.uk/~schisto/schistosoma/schisto_lifecycle_egg.html

Schistosoma mansoni worm
type: Class
subclass of: Schistosoma mansoni
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma mansoni worm stage
definition: A Schistosoma mansoni in the mature form that is capable of sexual reproduction, which lives in the small inferior mesenteric blood vessels surrounding the large intestine of the mammal host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni worm

Schistosoma haematobium 24 hour schistosomulum stage
type: Class
equivalent class: Class
  intersection of: 24 hour schistosomulum stage
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia skin
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma haematobium
subclass of: 24 hour schistosomulum stage
subclass of: Schistosoma haematobium schistosomulum stage
definition: A 24 hours schistosomulum stage of Schistosoma haematobium that occurs in the definitive host 24 hours post-infection.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: S. haematobium 24 hour schistosomulum stage

Plasmodium falciparum merozoite
type: Class
subclass of: Plasmodium falciparum
subclass of: Plasmodium merozoite
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium falciparum merozoite stage
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens erythrocyte
definition: A Plasmodium falciparum that is produced in a schizont, found in the bloodstream of a human host and invades erythrocytes.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parkh
alternative label: P. falciparum merozoite

Trypanosoma cruzi metacyclic trypomastigote stage
type: Class
equivalent class: Class
  intersection of: metacyclic trypomastigote stage
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia blood
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia macrophage
  intersection of: Restriction
    on property: in taxon
    some values from: Trypanosoma cruzi
subclass of: metacyclic trypomastigote stage
subclass of: Trypanosoma cruzi lifecycle stage
definition: A metacyclic trypomastigote stage in the lifecycle of Trypanosoma cruzi that occurs in a vertebrate host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: T. cruzi metacyclic trypomastigote stage

Schistosoma japonicum 24 hour schistosomulum
type: Class
subclass of: Schistosoma japonicum schistosomulum
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma japonicum 24 hour schistosomulum stage
subclass of: Restriction
  on property: located in
  some values from: Mammalia skin
definition: A Schistosoma japonicum schistosomulum in a migratory larval form that is found within blood vessels of the mammal, as definitive host, 24 hours post-infection.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. japonicum 24 hour schistosomulum

Homo sapiens lung
type: Class
equivalent class: Class
  intersection of: lung
  intersection of: Restriction
    on property: part of
    some values from: Homo sapiens
subclass of: Mammalia lung
definition: A lung that is a part of or originated from a human (Homo sapiens).
term editor: Priti Parikh
alternative label: human lung
has db xref: FMA:7195

Oncomelania hepatopancreas
type: Class
equivalent class: Class
  intersection of: hepatopancreas
  intersection of: Restriction
    on property: part of
    some values from: Oncomelania
subclass of: hepatopancreas
definition: Hepatopancreas that is a part of or originated from a Oncomelania snail.
term editor: Priti Parikh

Schistosoma mansoni egg stage
type: Class
equivalent class: Class
  intersection of: egg stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma mansoni
subclass of: egg stage
subclass of: Schistosoma mansoni lifecycle stage
definition: An egg stage in the lifecycle of Schistosoma mansoni that occurs in the mammalian host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni egg stage

Schistosoma mansoni 7 week worm
type: Class
subclass of: Schistosoma mansoni worm
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma mansoni 7 week worm stage
subclass of: Restriction
  on property: located in
  some values from: Mammalia mesenteric vein
subclass of: Restriction
  on property: located in
  some values from: Mammalia intestine
definition: A Schistosoma mansoni worm is the mature form of Schistosoma mansoni and capable of sexual reproduction, which is found in the small inferior mesenteric blood vessels surrounding the large intestine of the mammal host 7 weeks after infection of the mammalian host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni 7 week worm

Plasmodium falciparum sporozoite
type: Class
subclass of: Plasmodium falciparum
subclass of: Plasmodium sporozoite
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium falciparum sporozoite stage
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens hepatocyte
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens blood
subclass of: Restriction
  on property: located in
  some values from: Anopheles salivary gland
definition: A Plasmodium falciparum is formed in the oocyst. It migrates to and resides in the salivary glands of the mosquito vector. A distinction is made between oocyst-derived and salivary gland-derived sporozoites. Sporozoites invade hepatocytes in the vertebrate host.
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parkh
term editor: S. Khan
alternative label: P. falciparum sporozoite
definition source: Wikipedia: Plasmodium falciparum biology

Plasmodium falciparum oocyst
type: Class
subclass of: Plasmodium falciparum
subclass of: Plasmodium oocyst
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium falciparum oocyst stage
subclass of: Restriction
  on property: located in
  some values from: Anopheles midgut
definition: A Plasmodium falciparum that oocyst is formed, after traversal of the midgut wall by the ookinete stage, on the hemocoel side of the midgut wall of the mosquito vector.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: P. falciparum oocyst

Schistosoma japonicum 7 week worm stage
type: Class
equivalent class: Class
  intersection of: 7 week parasitic worm stage
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens mesenteric vein
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens intestine
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma japonicum
subclass of: Schistosoma japonicum worm stage
subclass of: 7 week parasitic worm stage
definition: A 7 week worm stage of Schistosoma japonicum that is the mature stage of Schistosoma japonicum and found in the small superior mesenteric blood vessels associated with the ileo-caecal area of the intestine of the definitive host 7 weeks after weeks after infection.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: S. japonicum 7 week worm stage

erythrocytic ring trophozoite stage
type: Class
subclass of: erythrocytic trophozoite stage
definition: An early trophozoite stage of Plasmodium sp. where a large central vacuole and peripheral nucleus give an appearance of a signet ring.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: http://www.biology.ualberta.ca/parasites/parpub/text/text/glossarR.htm

Homo sapiens intestine
type: Class
equivalent class: Class
  intersection of: intestine
  intersection of: Restriction
    on property: part of
    some values from: Homo sapiens
subclass of: Mammalia intestine
definition: An intestine that is a part of or originated from a human (Homo sapiens).
term editor: Priti Parikh
alternative label: human intestine
has db xref: FMA:7199

Schistosoma mansoni mother sporocyst stage
type: Class
equivalent class: Class
  intersection of: mother sporocyst stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma mansoni
subclass of: Schistosoma mansoni sporocyst stage
subclass of: mother sporocyst stage
definition: A mother sporocyst stage in the Schistosoma mansoni lifecycle that occurs in the snail intermediate host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni mother sporocyst stage

microgametocyte stage
type: Class
subclass of: gametocyte stage
definition: A gametocyte stage where a cell differentiates into a male sexual form called microgametocyte.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh

Schistosoma haematobium mother sporocyst
type: Class
subclass of: Schistosoma haematobium sporocyst
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma haematobium mother sporocyst stage
definition: A Schistosoma haematobium sporocyst that produces more sporocysts.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium mother sporocyst

Schistosoma japonicum mother sporocyst
type: Class
subclass of: Schistosoma japonicum sporocyst
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma japonicum mother sporocyst stage
definition: A Schistosoma japonicum sporocyst that produces more sporocysts.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. japonicum mother sporocyst

Plasmodium falciparum trophozoite
type: Class
subclass of: Plasmodium falciparum
subclass of: Plasmodium trophozoite
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium falciparum trophozoite stage
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens hepatocyte
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens erythrocyte
definition: A Plasmodium falciparum is a feeding form. The trophozoite stage has only 1 nucleus. Depending on its location, it is either called hepatic or erythrocytic trophozoite.
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parkh
term editor: S. Khan
alternative label: P. falciparum trophozoite

Schistosoma mansoni sporocyst
type: Class
subclass of: Schistosoma mansoni
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma mansoni sporocyst stage
definition: A Schistosoma mansoni is an elongated sac that develops from the miracidium within the snail indermediate host, and that either produces more sporocysts or develops into cercariae.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni sporocyst

7 week parasitic worm stage
type: Class
subclass of: parasitic worm stage
definition: A parasitic worm stage of development 7 weeks post differentiation into a worm form.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: PMID:19885392

metacyclic trypomastigote stage
type: Class
subclass of: trypomastigote stage
subclass of: Trypanosomatida metacyclic stage
subclass of: Restriction
  on property: realizes
  some values from: infectious agent role
definition: A trypomastigote stage of Trypanosoma species which are nondividing forms resistant to mammalian complement that have the capacity to infect mammalian cells.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh

gametocyte stage
type: Class
subclass of: life cycle stage
definition: A life cycle stage where a cell differentiates into male or female sexual forms.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh

promastigote stage
type: Class
subclass of: parasite lifecycle stage
subclass of: Restriction
  on property: in taxon
  some values from: Trypanosomatidae
definition: A parasite lifecycle stage of Trypanosomatids. In this stage, the flagellum is found anterior of nucleus and flagellum not attached to the cell body. The kinetoplast is located in front of the nucleus, near the anterior end of the body. (Wikipedia: Trypanosomatid)
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh

sporozoite stage
type: Class
subclass of: parasite lifecycle stage
subclass of: Restriction
  on property: in taxon
  some values from: parasite organism
definition: A parasite lifecycle stage of some sporozoans where cells divide through sporogony producing daughter cells called sporozoites that infect new hosts.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: http://www.biology.ualberta.ca/parasites/parpub/text/text/glossarS.htm

ookinete stage
type: Class
subclass of: parasite lifecycle stage
subclass of: Restriction
  on property: in taxon
  some values from: parasite organism
definition: A parasite lifecycle stage of some sporozoans where motile and elongated zygote is formed by the fertilization of the macrogamete during the sexual reproductive phase of the sporozoan life cycle, specifically the malarial parasite Plasmodium.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: Mosby's Medical Dictionary, 8th edition. � 2009, Elsevier. (http://medical-dictionary.thefreedictionary.com/ookinete)

Glossina salivary gland
type: Class
equivalent class: Class
  intersection of: saliva-secreting gland
  intersection of: Restriction
    on property: part of
    some values from: Glossina <genus>
subclass of: saliva-secreting gland
definition: A salivary gland that is a part of or originated from a tsetse fly of genus Glossina.
term editor: Priti Parikh

obsolete_Plasmodium falciparum
type: Class
subclass of: Obsolete Class
definition: Plasmodium falciparum is a protozoan parasite, one of the species of Plasmodium that cause malignant malaria in humans. It is transmitted by the female Anopheles mosquito.
editor note: Replaced by NCBITaxon term. Definition and axioms were added by OPL developers.
alternative label: P. falciparum
definition source: Wikipedia: Plasmodium falciparum
term replaced by: Plasmodium falciparum
deprecated: true

Schistosoma japonicum lifecycle stage
type: Class
equivalent class: Class
  intersection of: parasite lifecycle stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma japonicum
subclass of: parasite lifecycle stage
definition: A lifecycle stage of Schistosoma japonicum.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. japonicum lifecycle stage

Leishmania major amastigote stage
type: Class
equivalent class: Class
  intersection of: amastigote stage
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia macrophage
  intersection of: Restriction
    on property: in taxon
    some values from: Leishmania major
subclass of: amastigote stage
subclass of: Leishmania major lifecycle stage
definition: An amastigote stage in the lifecycle of Leishmania major that occurs in mammalian hosts.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: L. major amastigote stage

Plasmodium falciparum schizont stage
type: Class
equivalent class: Class
  intersection of: schizont stage
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens hepatocyte
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens erythrocyte
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: Plasmodium falciparum lifecycle stage
subclass of: Plasmodium schizont stage
definition: A schizont stage in the Plasmodium falciparum lifecycle that occurs in erythrocytes or in hepatocytes.
editor note: updated according to OPL terms Plasmodium final excel file from C. Janse, S. Khan
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parkh
term editor: S. Khan
alternative label: P. falciparum schizont stage

Schistosoma japonicum 3 day schistosomulum stage
type: Class
equivalent class: Class
  intersection of: 3 day schistosomulum stage
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia lung
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma japonicum
subclass of: Schistosoma japonicum 6 day schistosomulum stage
subclass of: 3 day schistosomulum stage
definition: A 3 days schistosomulum stage of Schistosoma japonicum that occurs in the definitive host 3 days post-infection.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: S. japonicum 3 day schistosomulum stage

Leishmania major procyclic promastigote
type: Class
subclass of: Leishmania major promastigote
subclass of: Restriction
  on property: participates in
  some values from: Leishmania major procyclic promastigote stage
subclass of: Restriction
  on property: located in
  some values from: Phlebotominae midgut
definition: A Leishmania major promastigote that is found in the alimentary tract of an insect vector. It is non-infective to its mammalian host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: L. major procyclic promastigote
definition source: PMID:11748963

Plasmodium falciparum zygote
type: Class
subclass of: Plasmodium falciparum
subclass of: Plasmodium zygote
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium falciparum zygote stage
subclass of: Restriction
  on property: located in
  some values from: Anopheles midgut
definition: A Plasmodium falciparum zygote is formed after fertilisation of the macrogamete by a microgamete in the midgut of the mosquito vector. This round form is the only diploid stage in the Plasmodium falciparum life cycle.
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: P. Parkh
term editor: S. Khan
alternative label: P. falciparum zygote
definition source: Wikipedia: Plasmodium falciparum biology

Plasmodium falciparum exflagellated microgametocyte
type: Class
subclass of: Plasmodium falciparum microgametocyte
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium falciparum exflagellated microgametocyte stage
subclass of: Restriction
  on property: located in
  some values from: Anopheles midgut
definition: A Plasmodium falciparum microgametocyte that is matured with flagellated motile microgametes still attached to its central body. Exflagellated microgametocyte of Plasmodium falciparum is found in the midgut of a mosquito vector.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Matt Berriman
term editor: Priti Parikh
alternative label: P. falciparum exflagellated microgametocyte

Schistosoma haematobium daughter sporocyst stage
type: Class
equivalent class: Class
  intersection of: daughter sporocyst stage
  intersection of: Restriction
    on property: occurs in
    some values from: Bulinus hepatopancreas
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma haematobium
subclass of: Schistosoma haematobium sporocyst stage
subclass of: daughter sporocyst stage
definition: A daughter sporocyst stage in the lifecycle of Schistosoma haematobium that occurs within the snail intermediate host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium daughter sporocyst stage

Trypanosoma cruzi trypomastigote
type: Class
subclass of: Trypanosoma cruzi
subclass of: Restriction
  on property: participates in
  some values from: Trypanosoma cruzi trypomastigote stage
subclass of: Restriction
  on property: located in
  some values from: Triatominae hindgut
subclass of: Restriction
  on property: located in
  some values from: Mammalia blood
subclass of: Restriction
  on property: located in
  some values from: Mammalia macrophage
definition: A Trypanosoma cruzi that is found in the bloodstream of infected mammals. It is a non-dividing form that is infectious for its insect vector.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: T. cruzi trypomastigote
definition source: http://dna.kdna.ucla.edu/parasite_course-old/cruzi_files/intro.htm

Plasmodium falciparum lifecycle stage
type: Class
equivalent class: Class
  intersection of: parasite lifecycle stage
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: parasite lifecycle stage
definition: A lifecycle stage of Plasmodium falciparum.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: P. falciparum lifecycle stage

Schistosoma haematobium sporocyst
type: Class
subclass of: Schistosoma haematobium
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma haematobium sporocyst stage
definition: A Schistosoma haematobium that is an elongated sac and develops from the miracidium within the snail indermediate host, and that either produces more sporocysts or develops into cercariae.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium sporocyst

Plasmodium falciparum macrogamete
type: Class
subclass of: Plasmodium falciparum gamete
subclass of: Plasmodium macrogamete
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium falciparum macrogamete stage
subclass of: Restriction
  on property: located in
  some values from: Anopheles midgut
definition: A Plasmodium falciparum gamete that is a matured form of the macrogametocyte and is found in the midgut of a mosquito vector. The macrogamete is fertilized by the microgamete, forming the zygote
term editor: Chris Stoeckert
term editor: Jie Zheng
alternative label: P. falciparum macrogamete

Schistosoma mansoni cercaria
type: Class
subclass of: Schistosoma mansoni
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma mansoni cercaria stage
definition: A Schistosoma mansoni in a parasitic larval form that develops in a freshwater snail and is released into the water.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni cercaria

Trypanosoma cruzi trypomastigote stage
type: Class
equivalent class: Class
  intersection of: trypomastigote stage
  intersection of: Restriction
    on property: occurs in
    some values from: Triatominae hindgut
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia blood
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia macrophage
  intersection of: Restriction
    on property: in taxon
    some values from: Trypanosoma cruzi
subclass of: trypomastigote stage
subclass of: Trypanosoma cruzi lifecycle stage
definition: A trypomastigote stage in the Trypanosoma cruzi lifecycle that occurs either in the vertebrate host or an insect vector.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: T. cruzi trypomastigote stage

Plasmodium falciparum microgamete stage
type: Class
equivalent class: Class
  intersection of: microgamete stage
  intersection of: Restriction
    on property: occurs in
    some values from: Anopheles midgut
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: Plasmodium falciparum gamete stage
subclass of: Plasmodium microgamete stage
definition: A microgamete stage in the Plasmodium falciparum lifecycle that occurs in the midgut of a mosquito vector.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: P. falciparum microgamete stage

human parasite role
type: Class
subclass of: parasite role
definition: A parasite role which is realized only during parasitic infection of a human.
editor note: previous def was not about a role.
term editor: Chris Stoeckert
term editor: Priti Parikh

24 hour schistosomulum stage
type: Class
subclass of: schistomulum stage
definition: A schistosomulum stage that occurs in 24 hours after infection of the mammalian host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: PMID:19885392

hypnozoite stage
type: Class
subclass of: parasite lifecycle stage
subclass of: Restriction
  on property: in taxon
  some values from: parasite organism
definition: A parasite lifecycle stage of some Plasmodium sp., such as Plasmodium vivax and Plasmodium ovale, the parasite in the liver cells do not achieve matuaration to a schizont immediately, but remain in a dormant form. This dormant form stage is called hypnozoite stage.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: Wikipedia: Plasmodium

Plasmodium falciparum microgamete
type: Class
subclass of: Plasmodium falciparum gamete
subclass of: Plasmodium microgamete
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium falciparum microgamete stage
subclass of: Restriction
  on property: located in
  some values from: Anopheles midgut
definition: A Plasmodium falciparum gamete that is a matured form of exflagellated microgametocyte and found in the midgut of a mosquito vector. The microgamete fertilizes the macrogamete, forming the zygote.
term editor: Chris Stoeckert
term editor: Jie Zheng
alternative label: P. falciparum microgamete

Trypanosoma brucei trypomastigote stage
type: Class
equivalent class: Class
  intersection of: trypomastigote stage
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia cerebrospinal fluid
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia blood
  intersection of: Restriction
    on property: in taxon
    some values from: Trypanosoma brucei
subclass of: trypomastigote stage
subclass of: Trypanosoma brucei lifecycle stage
definition: A trypomastigote stage in the Trypanosoma brucei lifecycle that occurs in the vertebrate host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: T. brucei trypomastigote stage

Homo sapiens ureter
type: Class
equivalent class: Class
  intersection of: ureter
  intersection of: Restriction
    on property: part of
    some values from: Homo sapiens
subclass of: ureter
definition: A ureter that is a part of or originated from a human (Homo sapiens).
term editor: Priti Parikh
alternative label: human ureter
has db xref: FMA:9704

Schistosoma haematobium lifecycle stage
type: Class
equivalent class: Class
  intersection of: parasite lifecycle stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma haematobium
subclass of: parasite lifecycle stage
definition: A lifecycle stage of Schistosoma haematobium.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium lifecycle stage

Schistosoma haematobium schistosomulum
type: Class
subclass of: Schistosoma haematobium
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma haematobium schistosomulum stage
definition: A Schistosoma haematobium in a migratory larval form that is found within blood vessels of the definitive host, mammal, and develops into the flatworm.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium schistosomulum

Schistosoma japonicum miracidium
type: Class
subclass of: Schistosoma japonicum
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma japonicum miracidium stage
definition: A Schistosoma japonicum in a free-living motile form that is covered with cilia, and develops in the snail intermediate host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. japonicum miracidium

egg stage
type: Class
subclass of: life cycle stage
definition: A life cycle stage of some parasites in which a non-operculate egg emerges from the adult female worm.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: http://www.path.cam.ac.uk/~schisto/schistosoma/schisto_lifecycle_egg.html

parasite lifecycle stage
type: Class
equivalent class: Class
  intersection of: life cycle stage
  intersection of: Restriction
    on property: in taxon
    some values from: parasite organism
subclass of: life cycle stage
definition: A life cycle stage of a parasite.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh

Trypanosoma brucei trypomastigote
type: Class
subclass of: Trypanosoma brucei
subclass of: Restriction
  on property: participates in
  some values from: Trypanosoma brucei trypomastigote stage
subclass of: Restriction
  on property: located in
  some values from: Mammalia cerebrospinal fluid
subclass of: Restriction
  on property: located in
  some values from: Mammalia blood
definition: A Trypanosoma brucei that is a Trypomastigote form of Trypanosoma brucei. In this form the large kinetoplast is postnuclear and is at the most posterior part of the body and the flagellum emerges from the flagellar pocket, and runs along the entire length of the body as an undulating membrane.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: T. brucei trypomastigote
definition source: http://dna.kdna.ucla.edu/parasite_course-old/african%20tryps%20new_files/contents1.htm

3 week parasitic worm stage
type: Class
subclass of: parasitic worm stage
definition: A parasitic worm stage of development 3 weeks post differentiation into a worm form.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: PMID:19885392

Schistosoma japonicum mother sporocyst stage
type: Class
equivalent class: Class
  intersection of: mother sporocyst stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma japonicum
subclass of: Schistosoma japonicum sporocyst stage
subclass of: mother sporocyst stage
definition: A mother sporocyst stage in the Schistosoma japonicum lifecycle that occurs in the snail intermediate host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. japonicum mother sporocyst stage

Trypanosoma cruzi lifecycle stage
type: Class
equivalent class: Class
  intersection of: parasite lifecycle stage
  intersection of: Restriction
    on property: in taxon
    some values from: Trypanosoma cruzi
subclass of: parasite lifecycle stage
definition: A lifecycle stage of Trypanosoma cruzi.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: T. cruzi lifecycle stage

Schistosoma japonicum sporocyst stage
type: Class
equivalent class: Class
  intersection of: sporocyst stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma japonicum
subclass of: sporocyst stage
subclass of: Schistosoma japonicum lifecycle stage
definition: A sporocyst stage in the Schistosoma japonicum lifecycle that is found within the snail intermediate host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. japonicum sporocyst stage

Plasmodium falciparum ookinete stage
type: Class
equivalent class: Class
  intersection of: ookinete stage
  intersection of: Restriction
    on property: occurs in
    some values from: Anopheles midgut
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: Plasmodium falciparum lifecycle stage
subclass of: Plasmodium ookinete stage
definition: An ookinete stage in the Plasmodium falciparum lifecycle that occurs in the midgut of a mosquito vector and on the outside of the midgut.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: P. falciparum ookinete stage

obsolete_Trypanosoma brucei bloodstream trypomastigote stage
type: Class
subclass of: Obsolete Class
definition: Bloodstream trypomastigote stage in the lifecycle of Trypanosoma brucei.
term editor: Priti Parikh
alternative label: T. brucei bloodstream trypomastigote stage
deprecated: true

Leishmania major promastigote stage
type: Class
equivalent class: Class
  intersection of: promastigote stage
  intersection of: Restriction
    on property: occurs in
    some values from: Phlebotominae proboscis
  intersection of: Restriction
    on property: occurs in
    some values from: Phlebotominae midgut
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia macrophage
  intersection of: Restriction
    on property: in taxon
    some values from: Leishmania major
subclass of: promastigote stage
subclass of: Leishmania major lifecycle stage
definition: A promastigote stage in the Leishmania major lifecycle.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: L. major promastigote stage

Plasmodium falciparum hepatic schizont
type: Class
subclass of: Plasmodium falciparum schizont
subclass of: Plasmodium hepatic schizont
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium falciparum hepatic schizont stage
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens hepatocyte
definition: A Plasmodium falciparum schizont that is found in infected hepatocytes (i.e., liver cells) of a human host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: P. falciparum hepatic schizont

Schistosoma mansoni daughter sporocyst
type: Class
subclass of: Schistosoma mansoni sporocyst
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma mansoni daughter sporocyst stage
subclass of: Restriction
  on property: located in
  some values from: Biomphalaria hepatopancreas
definition: A Schistosoma mansoni sporocyst that develops into cercariae.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni daughter sporocyst

Plasmodium falciparum gametocyte stage
type: Class
equivalent class: Class
  intersection of: gametocyte stage
  intersection of: Restriction
    on property: occurs in
    some values from: Anopheles midgut
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens erythrocyte
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: Plasmodium falciparum lifecycle stage
subclass of: Plasmodium gametocyte stage
definition: A gametocyte stage in the lifecycle of Plasmodium falciparum.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: P. falciparum gametocyte stage

Schistosoma japonicum 3 hour schistosomulum stage
type: Class
equivalent class: Class
  intersection of: 3 hour schistosomulum stage
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia skin
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma japonicum
subclass of: 3 hour schistosomulum stage
subclass of: Schistosoma japonicum schistosomulum stage
definition: A 3 hours schistosomulum stage of Schistosoma japonicum that occurs in the definitive host 3 hours post-infection.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. japonicum 3 hour schistosomulum stage

Phlebotominae midgut
type: Class
equivalent class: Class
  intersection of: midgut
  intersection of: Restriction
    on property: part of
    some values from: Phlebotominae
subclass of: midgut
definition: A midgut that is a part of or originated from a sand fly of genus Phlebotominae.
term editor: Priti Parikh

Schistosoma japonicum 24 hour schistosomulum stage
type: Class
equivalent class: Class
  intersection of: 24 hour schistosomulum stage
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia skin
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma japonicum
subclass of: Schistosoma japonicum schistosomulum stage
subclass of: 24 hour schistosomulum stage
definition: A 24 hours schistosomulum stage of Schistosoma japonicum that occurs in the definitive host 24 hours post-infection.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: S. japonicum 24 hour schistosomulum stage

Schistosoma mansoni mother sporocyst
type: Class
subclass of: Schistosoma mansoni sporocyst
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma mansoni mother sporocyst stage
definition: A Schistosoma mansoni sporocyst that produces more sporocysts.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni mother sporocyst

Schistosoma haematobium schistosomulum stage
type: Class
equivalent class: Class
  intersection of: schistomulum stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma haematobium
subclass of: schistomulum stage
subclass of: Schistosoma haematobium lifecycle stage
definition: A schistosomulum stage of Schistosoma haematobium that occurs in the definitive host and is followed by the parasitic worm stage.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium schistosomulum stage

Schistosoma haematobium adult male worm
type: Class
subclass of: Schistosoma haematobium adult worm
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma haematobium adult male worm stage
definition: A Schistosoma haematobium adult worm is a fully developed mature male form of Schistosoma haematobium and capable of sexual reproduction, which lives in the pelvic blood vessels of the vesicle plexis of the mammal host and has 4-5 testes.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium adult male worm
definition source: http://www.path.cam.ac.uk/~schisto/schistosoma/schisto_lifecycle_egg.html

Plasmodium falciparum zygote stage
type: Class
equivalent class: Class
  intersection of: zygote stage
  intersection of: Restriction
    on property: occurs in
    some values from: Anopheles midgut
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: Plasmodium falciparum lifecycle stage
subclass of: Plasmodium zygote stage
definition: A zygote stage in the Plasmodium falciparum lifecycle that occurs in the midgut of the mosquito vector where a microgamete and a macrogamete fertilizes each other to produce a diploid cell.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: P. falciparum zygote stage
definition source: Wikipedia: Plasmodium falciparum biology

Schistosoma haematobium egg
type: Class
subclass of: Schistosoma haematobium
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma haematobium egg stage
definition: A Schistosoma haematobium in an egg form that is laid by the female adult worm and released into the host gut where they leave the host in the faeces.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium egg

Schistosoma haematobium 6 day schistosomulum
type: Class
subclass of: Schistosoma haematobium schistosomulum
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma haematobium 6 day schistosomulum stage
subclass of: Restriction
  on property: located in
  some values from: Mammalia liver
definition: A Schistosoma haematobium schistosomulum in a migratory larval form that is found within blood vessels of mammal, as definitive host, 6 days post-infection.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium 6 day schistosomulum

Schistosoma haematobium 3 week worm stage
type: Class
equivalent class: Class
  intersection of: 3 week parasitic worm stage
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens urinary bladder
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma haematobium
subclass of: Schistosoma haematobium worm stage
subclass of: 3 week parasitic worm stage
definition: A worm stage of Schistosoma haematobium that is found in the pelvic blood vessels of the vesicle plexis of the definitive host 3 weeks after infection.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: S. haematobium 3 week worm stage

Schistosoma mansoni lifecycle stage
type: Class
equivalent class: Class
  intersection of: parasite lifecycle stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma mansoni
subclass of: parasite lifecycle stage
definition: A lifecycle stage of Schistosoma mansoni.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni lifecycle stage

Leishmania major amastigote
type: Class
subclass of: Leishmania major
subclass of: Restriction
  on property: participates in
  some values from: Leishmania major amastigote stage
subclass of: Restriction
  on property: located in
  some values from: Mammalia macrophage
definition: A Leishmania major that is the intracellular, non-motile form of the parasite found in the mammalian host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: L. major amastigote
definition source: http://dna.kdna.ucla.edu/parasite_course-old/leish_files/introduction1.htm

Schistosoma haematobium 3 day schistosomulum
type: Class
subclass of: Schistosoma haematobium schistosomulum
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma haematobium 3 day schistosomulum stage
subclass of: Restriction
  on property: located in
  some values from: Mammalia liver
definition: A Schistosoma haematobium schistosomulum in a migratory larval form that is found within blood vessels of mammal, as definitive host, 3 days post-infection.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium 3 day schistosomulum

Plasmodium falciparum macrogametocyte
type: Class
subclass of: Plasmodium falciparum gametocyte
subclass of: Plasmodium macrogametocyte
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium falciparum macrogametocyte stage
subclass of: Restriction
  on property: located in
  some values from: Anopheles midgut
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens erythrocyte
definition: A Plasmodium falciparum gametocyte that is a female gametocyte and found either in bloodstream of a human host or midgut of mosquito vector. The macrogametocyte is a precursor of the macrogamete.
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parkh
term editor: S. Khan
alternative label: P. falciparum macrogametocyte

Plasmodium falciparum erythrocytic trophozoite stage
type: Class
equivalent class: Class
  intersection of: erythrocytic trophozoite stage
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens erythrocyte
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: Plasmodium falciparum lifecycle stage
subclass of: Plasmodium erythrocytic trophozoite stage
definition: An erythrocytic trophozoite stage in the Plasmodium falciparum life cycle that occurs in erythrocytes of a human host.
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parkh
term editor: S. Khan
alternative label: P. falciparum erythrocytic trophozoite stage

Schistosoma mansoni miracidium
type: Class
subclass of: Schistosoma mansoni
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma mansoni miracidium stage
definition: A Schistosoma mansoni in a free-living motile form that is covered with cilia and develops in the snail intermediate host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni miracidium

Leishmania major lifecycle stage
type: Class
equivalent class: Class
  intersection of: parasite lifecycle stage
  intersection of: Restriction
    on property: in taxon
    some values from: Leishmania major
subclass of: parasite lifecycle stage
definition: A parasite lifecycle stage of Leishmania major.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: L. major lifecycle stage

Schistosoma mansoni cercaria stage
type: Class
equivalent class: Class
  intersection of: cercaria stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma mansoni
subclass of: cercaria stage
subclass of: Schistosoma mansoni lifecycle stage
definition: A cercaria stage in the lifecycle of Schistosoma mansoni that occurs in a freshwater snail and in fresh water.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni cercaria stage

Schistosoma mansoni worm stage
type: Class
equivalent class: Class
  intersection of: parasitic worm stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma mansoni
subclass of: parasitic worm stage
subclass of: Schistosoma mansoni lifecycle stage
definition: A worm stage of Schistosoma mansoni that is fully developed mature form and found in the small inferior mesenteric blood vessels surrounding the large intestine of the mammalian host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni worm stage

Schistosoma haematobium mother sporocyst stage
type: Class
equivalent class: Class
  intersection of: mother sporocyst stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma haematobium
subclass of: Schistosoma haematobium sporocyst stage
subclass of: mother sporocyst stage
definition: A mother sporocyst stage in the Schistosoma haematobium lifecycle that occurs in the snail intermediate host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium mother sporocyst stage

vesical venus plexus
type: Class
subclass of: material anatomical entity
definition: The vesical plexus envelops the lower part of the bladder and the base of the prostate and communicates with the pudendal and prostatic plexuses.
term editor: Priti Parikh
definition source: Wikipedia - Vesical venus plexus

mother sporocyst stage
type: Class
subclass of: sporocyst stage
definition: A sporocyst stage of Digenea formed after penetration of the miracidium into a mollusc; it lacks a gut and gives rise asexually to daughter sporocysts or rediae.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: http://www.biology.ualberta.ca/parasites/parpub/text/text/glossarM.htm

Glossina midgut
type: Class
equivalent class: Class
  intersection of: midgut
  intersection of: Restriction
    on property: part of
    some values from: Glossina <genus>
subclass of: midgut
definition: A midgut that is a part of or originated from a tsetse fly of genus Glossina.
term editor: Priti Parikh

Trypanosoma brucei epimastigote stage
type: Class
equivalent class: Class
  intersection of: epimastigote stage
  intersection of: Restriction
    on property: occurs in
    some values from: Glossina salivary gland
  intersection of: Restriction
    on property: in taxon
    some values from: Trypanosoma brucei
subclass of: Trypanosoma brucei lifecycle stage
subclass of: epimastigote stage
definition: An epimastigote stage in the lifecycle of Trypanosoma brucei.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: T. brucei epimastigote stage

Schistosoma mansoni 7 week worm stage
type: Class
equivalent class: Class
  intersection of: 7 week parasitic worm stage
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia mesenteric vein
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia intestine
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma mansoni
subclass of: 7 week parasitic worm stage
subclass of: Schistosoma mansoni worm stage
definition: A 7 week worm stage of Schistosoma mansoni that is the mature stage of Schistosoma mansoni and found in the small inferior mesenteric blood vessels surrounding the large intestine of the definitive host 7 weeks after weeks after infection.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: S. mansoni 7 week worm stage

Schistosoma mansoni 6 day schistosomulum
type: Class
subclass of: Schistosoma mansoni schistosomulum
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma mansoni 6 day schistosomulum stage
subclass of: Restriction
  on property: located in
  some values from: Mammalia lung
definition: A Schistosoma mansoni schistosomulum in a migratory larval formi that is found within blood vessels of the definitive host, mammal, 6 days post-infection.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni 6day schistosomulum

Homo sapiens urinary bladder
type: Class
equivalent class: Class
  intersection of: urinary bladder
  intersection of: Restriction
    on property: part of
    some values from: Homo sapiens
subclass of: urinary bladder
definition: A urinary bladder that is a part of or originated from a human (Homo sapiens).
term editor: Priti Parikh
alternative label: human bladder
alternative label: human urinary bladder
has db xref: FMA:15900

Schistosoma mansoni daughter sporocyst stage
type: Class
equivalent class: Class
  intersection of: daughter sporocyst stage
  intersection of: Restriction
    on property: occurs in
    some values from: Biomphalaria hepatopancreas
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma mansoni
subclass of: Schistosoma mansoni sporocyst stage
subclass of: daughter sporocyst stage
definition: A daughter sporocyst stage of Schistosoma mansoni that occurs in the snail intermediate host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni daughter sporocyst stage

3 day schistosomulum stage
type: Class
subclass of: schistomulum stage
definition: A schistosomulum stage that occurs in 3 days after infection of the mammalian host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
definition source: PMID:19885392

Plasmodium falciparum erythrocytic ring trophozoite
type: Class
subclass of: Plasmodium falciparum erythrocytic trophozoite
subclass of: Plasmodium erythrocytic ring trophozoite
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium falciparum erythrocytic ring trophozoite stage
definition: A Plasmodium falciparum erythrocytic trophozoite that is found in erythrocytes. It is a young trophozoite stage that has a typical 'ring-like' appearance. Ring-form trophozoites of Plasmodium falciparum are often thin and delicate, measuring on average 1/5 the diameter of the red blood cell.
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parkh
term editor: S. Khan
alternative label: P. falciparum erythrocytic ring trophozoite
definition source: http://www.dpd.cdc.gov/dpdx/html/frames/m-r/malaria/falciparum/body_malariadffalcring.htm

Trypanosoma cruzi epimastigote stage
type: Class
equivalent class: Class
  intersection of: epimastigote stage
  intersection of: Restriction
    on property: occurs in
    some values from: Triatominae midgut
  intersection of: Restriction
    on property: in taxon
    some values from: Trypanosoma cruzi
subclass of: epimastigote stage
subclass of: Trypanosoma cruzi lifecycle stage
definition: An epimastigote stage in the lifecycle of Trypanosoma cruzi.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: T. cruzi epimastigote stage

Schistosoma japonicum adult female worm stage
type: Class
equivalent class: Class
  intersection of: adult female parasitic worm stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma japonicum
subclass of: adult female parasitic worm stage
subclass of: Schistosoma japonicum adult worm stage
definition: An adult female worm stage of Schistosoma japonicum that is fully developed mature female stage of Schistosoma japonicum and occurs in the small superior mesenteric blood vessels associated with the ileo-caecal area of the intestine of the mammalian host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: S. japonicum adult female worm stage

Schistosoma japonicum adult male worm stage
type: Class
equivalent class: Class
  intersection of: adult male parasitic worm stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma japonicum
subclass of: adult male parasitic worm stage
subclass of: Schistosoma japonicum adult worm stage
definition: An adult male worm stage of Schistosoma japonicum that is fully developed mature male stage of Schistosoma japonicum and occurs in the small superior mesenteric blood vessels associated with the ileo-caecal area of the intestine of the mammalian host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: S. japonicum adult male worm stage

Schistosoma japonicum adult worm
type: Class
subclass of: Schistosoma japonicum worm
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma japonicum adult worm stage
definition: A Schistosoma japonicum worm is a fully developed mature form of Schistosoma japonicum and capable of sexual reproduction, which lives in the small superior mesenteric blood vessels associated with the ileo-caecal area of the intestine of the mammal host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: S. japonicum adult worm

Schistosoma mansoni adult worm
type: Class
subclass of: Schistosoma mansoni worm
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma mansoni adult worm stage
definition: A Schistosoma mansoni worm is the fully developed mature form of Schistosoma mansoni and capable of sexual reproduction, which lives in the small inferior mesenteric blood vessels surrounding the large intestine of the mammal host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni adult worm

Schistosoma haematobium adult male worm stage
type: Class
equivalent class: Class
  intersection of: adult male parasitic worm stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma haematobium
subclass of: adult male parasitic worm stage
subclass of: Schistosoma haematobium adult worm stage
definition: An adult male worm stage of Schistosoma haematobium that is fully developed mature male stage of Schistosoma haematobium and found in the pelvic blood vessels of the vesicle plexis of the mammalian host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: S. haematobium adult male worm stage

Schistosoma japonicum adult male worm
type: Class
subclass of: Schistosoma japonicum adult worm
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma japonicum adult male worm stage
definition: A Schistosoma japonicum adult worm is a fully developed mature male form of Schistosoma japonicum and capable of sexual reproduction, which lives in the small superior mesenteric blood vessels associated with the ileo-caecal area of the intestine of the mammal host and has 4-5 testes.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: S. japonicum adult male worm

Schistosoma mansoni adult male worm stage
type: Class
equivalent class: Class
  intersection of: adult male parasitic worm stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma mansoni
subclass of: adult male parasitic worm stage
subclass of: Schistosoma mansoni adult worm stage
definition: An adult male worm stage of Schistosoma mansoni that is fully developed mature male stage of Schistosoma mansoni and found in the small inferior mesenteric blood vessels surrounding the large intestine of the mammalian host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: S. mansoni adult male worm stage

Schistosoma mansoni adult female worm
type: Class
subclass of: Schistosoma mansoni adult worm
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma mansoni adult female worm stage
definition: A Schistosoma mansoni adult worm is the fully developed mature female form of Schistosoma mansoni and capable of sexual reproduction, which lives within the gynacophoric canal of the adult male worm in the small inferior mesenteric blood vessels surrounding the large intestine of the mammal host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni adult female worm

parasite organism
type: Class
equivalent class: Class
  intersection of: organism
  intersection of: Restriction
    on property: has role
    some values from: parasite role
subclass of: organism
definition: An organism living in, with, or on another organism in parasitism. Individual members of parasite species, such as Leishmania, Plasmodium, Trypanosoma, etc. are members of this class.
term editor: Jie Zheng
term editor: Priti Parikh
definition source: http://www.merriam-webster.com/dictionary/parasite

Schistosoma haematobium adult worm
type: Class
subclass of: Schistosoma haematobium worm
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma haematobium adult worm stage
definition: A Schistosoma haematobium worm is a fully developed mature form of Schistosoma haematobium and capable of sexual reproduction, which lives in the pelvic blood vessels of the vesicle plexis of the mammal host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium adult worm

Schistosoma haematobium adult female worm stage
type: Class
equivalent class: Class
  intersection of: adult female parasitic worm stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma haematobium
subclass of: adult female parasitic worm stage
subclass of: Schistosoma haematobium adult worm stage
definition: An adult female worm stage of Schistosoma haematobium that is fully developed mature female stage of Schistosoma haematobium and found in the pelvic blood vessels of the vesicle plexis of the mammalian host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: S. haematobium adult female worm stage

Schistosoma haematobium adult female worm
type: Class
subclass of: Schistosoma haematobium adult worm
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma haematobium adult female worm stage
definition: A Schistosoma haematobium adult worm is a fully developed mature female form of Schistosoma haematobium and capable of sexual reproduction, which lives within the gynacophoric canal of the adult male worm in the pelvic blood vessels of the vesicle plexis of the mammal host.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. haematobium adult female worm

Schistosoma mansoni adult female worm stage
type: Class
equivalent class: Class
  intersection of: adult female parasitic worm stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma mansoni
subclass of: adult female parasitic worm stage
subclass of: Schistosoma mansoni adult worm stage
definition: An adult female worm stage of Schistosoma mansoni that is fully developed mature female stage of Schistosoma mansoni and found in the small inferior mesenteric blood vessels surrounding the large intestine of the mammalian host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: S. mansoni adult female worm stage

adult parasitic worm stage
type: Class
subclass of: parasitic worm stage
definition: A parasitic worm stage where the worm is matured and ready to pair up with another adult worm of the opposite gender, and reproduce.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: http://www.path.cam.ac.uk/~schisto/schistosoma/schisto_lifecycle_egg.html

Schistosoma japonicum adult female worm
type: Class
subclass of: Schistosoma japonicum adult worm
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma japonicum adult female worm stage
definition: A Schistosoma japonicum adult worm is a fully developed mature female form of Schistosoma japonicum and capable of sexual reproduction, which lives within the gynacophoric canal of the adult male worm in the small superior mesenteric blood vessels associated with the ileo-caecal area of the intestine of the mammal host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
alternative label: S. japonicum adult female worm

adult male parasitic worm stage
type: Class
subclass of: adult parasitic worm stage
definition: An adult worm stage of a male parasitic worm.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Priti Parikh
definition source: http://www.path.cam.ac.uk/~schisto/schistosoma/schisto_lifecycle_egg.html

Schistosoma mansoni adult male worm
type: Class
subclass of: Schistosoma mansoni adult worm
subclass of: Restriction
  on property: participates in
  some values from: Schistosoma mansoni adult male worm stage
definition: A Schistosoma mansoni adult worm is the fully developed mature male form of Schistosoma mansoni and capable of sexual reproduction, which lives in the small inferior mesenteric blood vessels surrounding the large intestine of the mammal host and has 4-5 testes.
term editor: Anna Protasio
term editor: Chris Stoeckert
term editor: Flora Logan
term editor: Jie Zheng
alternative label: S. mansoni adult male worm

Plasmodium falciparum hepatic merozoite
type: Class
subclass of: Plasmodium falciparum merozoite
subclass of: Plasmodium hepatic merozoite
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium falciparum hepatic merozoite stage
definition: A Plasmodium falciparum merozoite that is produced in a hepatic schizont and released into the bloodstream of a human host. These forms invade erythrocytes.
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: S. Khan
alternative label: P. falciparum hepatic merozoite

Plasmodium falciparum erythrocytic merozoite
type: Class
subclass of: Plasmodium falciparum merozoite
subclass of: Plasmodium erythrocytic merozoite
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium falciparum erythrocytic merozoite stage
definition: A Plasmodium falciparum merozoite that is produced in an erythrocytic schizont and released into the bloodstream of a human host. These forms invade erythrocytes.
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: S. Khan
alternative label: P. falciparum erythrocytic merozoite

erythrocytic trophozoite stage
type: Class
subclass of: trophozoite stage
subclass of: Restriction
  on property: occurs in
  some values from: erythrocyte
definition: A trophozoite stage in some protozoan parasite life cycle that occurs in erythrocytes.
editor note: definition adapted from that for P. falciparum erythrocytic trophozoite stage and parent trophozoite stage
term editor: Chris Stoeckert

Plasmodium falciparum erythrocytic trophozoite
type: Class
subclass of: Plasmodium falciparum trophozoite
subclass of: Plasmodium erythrocytic trophozoite
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium falciparum erythrocytic trophozoite stage
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens erythrocyte
definition: A Plasmodium falciparum trophozoite that is found in erythrocytes. It is a feeding stage with a single nucleus.
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: S. Khan
alternative label: P. falciparum erythrocytic trophozoite

Plasmodium falciparum erythrocytic merozoite stage
type: Class
equivalent class: Class
  intersection of: erythrocytic merozoite stage
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: Plasmodium falciparum lifecycle stage
subclass of: Plasmodium erythrocytic merozoite stage
definition: An erythrocytic merozoite stage in the Plasmodium falciparum lifecycle that occurs in the bloodstream of a human host.
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: S. Khan
alternative label: P. falciparum erythrocytic merozoite stage

Plasmodium falciparum hepatic merozoite stage
type: Class
equivalent class: Class
  intersection of: hepatic merozoite stage
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: Plasmodium falciparum lifecycle stage
subclass of: Plasmodium hepatic merozoite stage
definition: A hepatic merozoite stage in the Plasmodium falciparum lifecycle that occurs in the hepatocyte of a human host.
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: S. Khan
alternative label: P. falciparum hepatic merozoite stage

hepatic merozoite stage
type: Class
subclass of: merozoite stage
subclass of: Restriction
  on property: occurs in
  some values from: hepatocyte
definition: A merozoite stage in the Plasmodium lifecycle that occurs in the hepatocyte of a vertebrate host.
editor note: definition adapted from that for P. falciparum hepatic merozoite stage
term editor: Chris Stoeckert
term editor: Jie Zheng

erythrocytic merozoite stage
type: Class
subclass of: merozoite stage
definition: A merozoite stage in the apicomplexan lifecycle that occurrs in the bloodstream of a vertebrate host.
editor note: definition adapted from that for P. falciparum salivary erythrocytic merozoite stage and from the general merozoite definition
term editor: Chris Stoeckert
term editor: Jie Zheng

Plasmodium falciparum gametocyte
type: Class
subclass of: Plasmodium falciparum
subclass of: Plasmodium gametocyte
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium falciparum gametocyte stage
subclass of: Restriction
  on property: located in
  some values from: Anopheles midgut
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens erythrocyte
definition: A Plasmodium falciparum that is located either in the bloodstream of the human host or midgut of mosquito vector. Gametocytes are the precursor cells of the macro- or micro-gametes.
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: K. Louis
term editor: S Khan

Plasmodium falciparum hepatic trophozoite stage
type: Class
equivalent class: Class
  intersection of: hepatic trophozoite stage
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens hepatocyte
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: Plasmodium falciparum lifecycle stage
subclass of: Plasmodium hepatic trophozoite stage
definition: A hepatic trophozoite stage in the Plasmodium falciparum life cycle that occurs in hepatocytes of a human host.
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: S. Khan
alternative label: P. falciparum hepatic trophozoite stage

Plasmodium falciparum trophozoite stage
type: Class
equivalent class: Class
  intersection of: trophozoite stage
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens hepatocyte
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens erythrocyte
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: Plasmodium falciparum lifecycle stage
subclass of: Plasmodium trophozoite stage
definition: A trophozoite stage in the Plasmodium falciparum lifecycle that occurs in a human host.
term editor: Chris Stoeckert
term editor: Jie Zheng
alternative label: P. falciparum trophozoite stage

Plasmodium falciparum oocyst-derived sporozoite stage
type: Class
equivalent class: Class
  intersection of: oocyst-derived sporozoite stage
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: Plasmodium falciparum lifecycle stage
subclass of: Plasmodium oocyst-derived sporozoite stage
definition: A sporozoite stage in the Plasmodium falciparum lifecycle that occurs in the hemocoel and the salivary glands of the mosquito. Sporozoites invade hepatocytes in the human host.
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: S. Khan

salivary gland-derived sporozoite stage
type: Class
subclass of: sporozoite stage
subclass of: Restriction
  on property: occurs in
  some values from: saliva-secreting gland
definition: A sporozoite stage in the Plasmodium lifecycle that occurs in the hemocoel and the salivary glands of the mosquito. Sporozoites invade hepatocytes in the vertebrate host.
editor note: definition adapted from that for P. falciparum salivary gland derived sporozoite stage
term editor: Chris Stoeckert

Plasmodium falciparum salivary gland-derived sporozoite stage
type: Class
equivalent class: Class
  intersection of: salivary gland-derived sporozoite stage
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: Plasmodium falciparum lifecycle stage
subclass of: Plasmodium salivary gland-derived sporozoite stage
definition: A salivary gland-derived sporozoite stage in the Plasmodium falciparum lifecycle that occurs in the hemocoel and the salivary glands of the mosquito. Sporozoites invade hepatocytes in the human host.
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: S. Khan

Plasmodium falciparum salivary gland-derived sporozoite
type: Class
subclass of: Plasmodium falciparum sporozoite
subclass of: Plasmodium salivary gland-derived sporozoite
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium falciparum salivary gland-derived sporozoite stage
definition: A Plasmodium falciparum sporozoite that is formed in the oocyst. It migrates to and resides in the salivary glands of the mosquito vector. Sporozoites invade hepatocytes in a human host.
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: S. Khan
alternative label: P. falciparum salivary gland-derived sporozoite

oocyst-derived sporozoite stage
type: Class
subclass of: sporozoite stage
definition: A sporozoite stage in some parasite lifecycle that occurs in the hemocoel and the salivary glands of the mosquito. Sporozoites invade hepatocytes in the vertebrate host.
editor note: definition adapted from that for P. falciparum oocyte derived sporozoite stage
term editor: Chris Stoeckert

Plasmodium falciparum hepatic trophozoite
type: Class
subclass of: Plasmodium falciparum trophozoite
subclass of: Plasmodium hepatic trophozoite
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium falciparum hepatic trophozoite stage
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens hepatocyte
definition: A Plasmodium falciparum trophozoite that is found in hepatocytes of a human host. It is a feeding stage with a single nucleus
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: S. Khan
alternative label: P. falciparum hepatic trophozoite

Plasmodium falciparum gamete
type: Class
subclass of: Plasmodium falciparum
subclass of: Plasmodium gamete
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium falciparum gamete stage
subclass of: Restriction
  on property: located in
  some values from: Anopheles midgut
definition: A Plasmodium falciparum that is found in midgut of mosquito vector. There are two forms of gametes: micro- and macrogametocytes.
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: S. Khan
alternative label: P. falciparum gamete

Plasmodium falciparum oocyst-derived sporozoite
type: Class
subclass of: Plasmodium falciparum sporozoite
subclass of: Plasmodium oocyst-derived sporozoite
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium falciparum oocyst-derived sporozoite stage
definition: A Plasmodium falciparum sporozoite that is found in the infected hepatocytes of a human host.
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: S. Khan
alternative label: P. falciparum oocyst-derived sporozoite

gamete stage
type: Class
subclass of: life cycle stage
definition: A life cycle stage of some parasites that develop into mature sexual cells.
term editor: Jie Zheng

hepatic trophozoite stage
type: Class
subclass of: trophozoite stage
subclass of: Restriction
  on property: occurs in
  some values from: hepatocyte
definition: A trophozoite stage in some protozoan parasite life cycle that occurs in hepatocytes.
editor note: definition adapted from that for P. falciparum hepatic trophozoite stage and from parent trophozoite stage
term editor: Chris Stoeckert

Plasmodium falciparum gamete stage
type: Class
equivalent class: Class
  intersection of: gamete stage
  intersection of: Restriction
    on property: occurs in
    some values from: Anopheles midgut
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium falciparum
subclass of: Plasmodium falciparum lifecycle stage
subclass of: Plasmodium gamete stage
definition: A gamete stage in the Plasmodium falciparum lifecycle that occurs in the midgut of a mosquito vector.
term editor: C. Janse
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: S. Khan
alternative label: P. falciparum gamete stage

asexual lifecycle in host red blood cell stage
type: Class
subclass of: parasite lifecycle stage
subclass of: Restriction
  on property: occurs in
  some values from: erythrocyte
subclass of: Restriction
  on property: in taxon
  some values from: parasite organism
definition: A parasite lifecycle stage that occurs as a result of asexual replication in the red blood cells of the host organism. For Plasmodium species these stages can include merozoites, trophozoites, and schizonts.
term editor: Chris Stoeckert
alternative label: asexual blood stage
definition source: VEuPathDB

Plasmodium gamete
type: Class
equivalent class: Class
  intersection of: Plasmodium
  intersection of: Restriction
    on property: participates in
    some values from: gamete stage
subclass of: Plasmodium
definition: A Plasmodium that is found in the midgut of a mosquito vector during gamete lifecycle stage. There are two forms of gametes: micro- and macrogametocytes.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Ulrike Boehme
term tracker item: https://github.com/OPL-ontology/OPL/issues/2
ontology term requester: GeneDB

Plasmodium macrogamete
type: Class
equivalent class: Class
  intersection of: Plasmodium
  intersection of: Restriction
    on property: participates in
    some values from: macrogamete stage
  intersection of: Restriction
    on property: located in
    some values from: Anopheles midgut
subclass of: Plasmodium gamete
definition: A Plasmodium gamete that is in a matured form of the macrogametocyte and found in the midgut of a mosquito vector. The macrogamete is fertilized by the microgamete, forming the zygote.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Ulrike Boehme
term tracker item: https://github.com/OPL-ontology/OPL/issues/2
ontology term requester: GeneDB

Plasmodium microgamete
type: Class
equivalent class: Class
  intersection of: Plasmodium
  intersection of: Restriction
    on property: participates in
    some values from: microgamete stage
  intersection of: Restriction
    on property: located in
    some values from: Anopheles midgut
subclass of: Plasmodium gamete
definition: A Plasmodium gamete that is in a matured form of exflagellated microgametocyte and found in the midgut of a mosquito vector. The microgamete fertilises the macrogamete, forming the zygote.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Ulrike Boehme
term tracker item: https://github.com/OPL-ontology/OPL/issues/2
ontology term requester: GeneDB

Plasmodium gametocyte
type: Class
equivalent class: Class
  intersection of: Plasmodium
  intersection of: Restriction
    on property: participates in
    some values from: gametocyte stage
subclass of: Plasmodium
definition: A Plasmodium that is located either in the bloodstream of the vertebrate host or midgut of mosquito vector during gametocyte stage. Gametocytes are the precursor cells of the macro- or microgametes
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Ulrike Boehme
term tracker item: https://github.com/OPL-ontology/OPL/issues/2
ontology term requester: GeneDB

Plasmodium macrogametocyte
type: Class
equivalent class: Class
  intersection of: Plasmodium
  intersection of: Restriction
    on property: participates in
    some values from: macrogametocyte stage
  intersection of: Restriction
    on property: located in
    some values from: Anopheles midgut
  intersection of: Restriction
    on property: located in
    some values from: Vertebrate erythrocyte
subclass of: Plasmodium gametocyte
definition: A Plasmodium gametocyte that is a female gametocyte of Plasmodium and found either in the bloodstream of the vertebrate host or midgut of mosquito vector. The macrogametocyte is a precursor of the macrogamete.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Ulrike Boehme
term tracker item: https://github.com/OPL-ontology/OPL/issues/2
ontology term requester: GeneDB

Plasmodium microgametocyte
type: Class
equivalent class: Class
  intersection of: Plasmodium
  intersection of: Restriction
    on property: participates in
    some values from: microgametocyte stage
  intersection of: Restriction
    on property: located in
    some values from: Anopheles midgut
  intersection of: Restriction
    on property: located in
    some values from: Vertebrate erythrocyte
subclass of: Plasmodium gametocyte
definition: A Plasmodium gametocyte that is a male gametocyte of Plasmodium and found either in the bloodstream of a vertebrate host or midgut of a mosquito vector. The microgametocyte is a precursor cell of the microgamete
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Ulrike Boehme
term tracker item: https://github.com/OPL-ontology/OPL/issues/2
ontology term requester: GeneDB

Plasmodium merozoite
type: Class
equivalent class: Class
  intersection of: Plasmodium
  intersection of: Restriction
    on property: participates in
    some values from: merozoite stage
subclass of: Plasmodium
definition: A Plasmodium that is during merozoite lifecycle stage, occurs in the bloodstream of a vertebrate host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Ulrike Boehme
term tracker item: https://github.com/OPL-ontology/OPL/issues/2
ontology term requester: GeneDB

Plasmodium erythrocytic merozoite
type: Class
equivalent class: Class
  intersection of: Plasmodium
  intersection of: Restriction
    on property: participates in
    some values from: erythrocytic merozoite stage
subclass of: Plasmodium merozoite
definition: A Plasmodium merozoite that is produced in an erythrocytic schizont and released into the bloodstream of a vertebrate host. These forms invade erythrocytes.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Ulrike Boehme
term tracker item: https://github.com/OPL-ontology/OPL/issues/2
ontology term requester: GeneDB

Plasmodium hepatic merozoite
type: Class
equivalent class: Class
  intersection of: Plasmodium
  intersection of: Restriction
    on property: participates in
    some values from: hepatic merozoite stage
subclass of: Plasmodium merozoite
definition: A Plasmodium merozoite that is produced in a hepatic schizont and released into the bloodstream of a vertebrate host. These forms invade erythrocytes.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Ulrike Boehme
term tracker item: https://github.com/OPL-ontology/OPL/issues/2
ontology term requester: GeneDB

Plasmodium oocyst
type: Class
equivalent class: Class
  intersection of: Plasmodium
  intersection of: Restriction
    on property: participates in
    some values from: oocyst stage
  intersection of: Restriction
    on property: located in
    some values from: Anopheles midgut
subclass of: Plasmodium
definition: A Plasmodium that is formed after traversal of the midgut wall by the ookinete stage, on the hemocoel side of the midgut wall of the mosquito vector.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Ulrike Boehme
term tracker item: https://github.com/OPL-ontology/OPL/issues/2
ontology term requester: GeneDB

Plasmodium ookinete
type: Class
equivalent class: Class
  intersection of: Plasmodium
  intersection of: Restriction
    on property: participates in
    some values from: ookinete stage
  intersection of: Restriction
    on property: located in
    some values from: Anopheles midgut
subclass of: Plasmodium
definition: A Plasmodium that is a 'banana-shaped' form originates from the round zygote. The ookinete is found in the midgut of a mosquito vector and traverses the midgut wall of a mosquito vector.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Ulrike Boehme
term tracker item: https://github.com/OPL-ontology/OPL/issues/2
ontology term requester: GeneDB

Plasmodium schizont
type: Class
equivalent class: Class
  intersection of: Plasmodium
  intersection of: Restriction
    on property: participates in
    some values from: schizont stage
subclass of: Plasmodium
definition: A Plasmodium that is a form divides through schizogony. Depending on its location, it is either called hepatic or erythrocytic schizont. The schizont is a dividing stage with 2 or more nuclei.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Ulrike Boehme
term tracker item: https://github.com/OPL-ontology/OPL/issues/2
ontology term requester: GeneDB

Plasmodium erythrocytic schizont
type: Class
equivalent class: Class
  intersection of: Plasmodium
  intersection of: Restriction
    on property: participates in
    some values from: erythrocytic schizont stage
  intersection of: Restriction
    on property: located in
    some values from: Vertebrate erythrocyte
subclass of: Plasmodium schizont
definition: A Plasmodium schizont that is found in infected erythrocytes of a vertebrate host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Ulrike Boehme
term tracker item: https://github.com/OPL-ontology/OPL/issues/2
ontology term requester: GeneDB

Plasmodium hepatic schizont
type: Class
equivalent class: Class
  intersection of: Plasmodium
  intersection of: Restriction
    on property: participates in
    some values from: hepatic schizont stage
  intersection of: Restriction
    on property: located in
    some values from: Vertebrate hepatocyte
subclass of: Plasmodium schizont
definition: A Plasmodium schizont that is found in infected hepatocytes (i.e. liver cells) of a vertebrate host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Ulrike Boehme
term tracker item: https://github.com/OPL-ontology/OPL/issues/2
ontology term requester: GeneDB

Plasmodium sporozoite
type: Class
equivalent class: Class
  intersection of: Plasmodium
  intersection of: Restriction
    on property: participates in
    some values from: sporozoite stage
  intersection of: Restriction
    on property: located in
    some values from: Anopheles salivary gland
  intersection of: Restriction
    on property: located in
    some values from: Vertebrate blood
  intersection of: Restriction
    on property: located in
    some values from: Vertebrate hepatocyte
subclass of: Plasmodium
definition: A Plasmodium that is formed in the oocyst and migrates to and reside in the salivary glands of the mosquito vector. A distinction is made between oocyst-derived and salivary gland-derived sporozoites. Sporozoites invade hepatocytes in the vertebrate host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Ulrike Boehme
term tracker item: https://github.com/OPL-ontology/OPL/issues/2
ontology term requester: GeneDB

Plasmodium oocyst-derived sporozoite
type: Class
equivalent class: Class
  intersection of: Plasmodium
  intersection of: Restriction
    on property: participates in
    some values from: oocyst-derived sporozoite stage
subclass of: Plasmodium
definition: A Plasmodium sporozoite that is found in the infected hepatocytes of a vertebrate host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Ulrike Boehme
term tracker item: https://github.com/OPL-ontology/OPL/issues/2
ontology term requester: GeneDB

Plasmodium salivary gland-derived sporozoite
type: Class
equivalent class: Class
  intersection of: Plasmodium
  intersection of: Restriction
    on property: participates in
    some values from: salivary gland-derived sporozoite stage
subclass of: Plasmodium
definition: A Plasmodium sporozoite that is found in the salivary glands of the mosquito vector.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Ulrike Boehme
term tracker item: https://github.com/OPL-ontology/OPL/issues/2
ontology term requester: GeneDB

Plasmodium trophozoite
type: Class
equivalent class: Class
  intersection of: Plasmodium
  intersection of: Restriction
    on property: participates in
    some values from: trophozoite stage
  intersection of: Restriction
    on property: located in
    some values from: Vertebrate erythrocyte
  intersection of: Restriction
    on property: located in
    some values from: Vertebrate hepatocyte
subclass of: Plasmodium
definition: A Plasmodium that is a feeding form which has a single nucleus during the trophozoite stage. Depending on its location, it is either called hepatic or erythrocytic trophozoite.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Ulrike Boehme
term tracker item: https://github.com/OPL-ontology/OPL/issues/2
ontology term requester: GeneDB

Plasmodium erythrocytic trophozoite
type: Class
equivalent class: Class
  intersection of: Plasmodium
  intersection of: Restriction
    on property: participates in
    some values from: erythrocytic trophozoite stage
  intersection of: Restriction
    on property: located in
    some values from: Vertebrate erythrocyte
subclass of: Plasmodium
definition: A Plasmodium trophozoite that is found in erythrocytes of a vertebrate host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Ulrike Boehme
term tracker item: https://github.com/OPL-ontology/OPL/issues/2
ontology term requester: GeneDB

Plasmodium erythrocytic ring trophozoite
type: Class
equivalent class: Class
  intersection of: Plasmodium
  intersection of: Restriction
    on property: participates in
    some values from: erythrocytic ring trophozoite stage
subclass of: Plasmodium
definition: A Plasmodium erythrocytic trophozoite that has a typical 'ring-like' appearance. Ring-form trophozoites of Plasmodium are often thin and delicate, measuring on average 1/5 the diameter of the red blood cell.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Ulrike Boehme
term tracker item: https://github.com/OPL-ontology/OPL/issues/2
ontology term requester: GeneDB

Plasmodium hepatic trophozoite
type: Class
equivalent class: Class
  intersection of: Plasmodium
  intersection of: Restriction
    on property: participates in
    some values from: hepatic trophozoite stage
  intersection of: Restriction
    on property: located in
    some values from: Vertebrate hepatocyte
subclass of: Plasmodium
definition: A Plasmodium trophozoite that is found in hepatocytes.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Ulrike Boehme
term tracker item: https://github.com/OPL-ontology/OPL/issues/2
ontology term requester: GeneDB

Plasmodium zygote
type: Class
equivalent class: Class
  intersection of: Plasmodium
  intersection of: Restriction
    on property: participates in
    some values from: zygote stage
  intersection of: Restriction
    on property: located in
    some values from: Anopheles midgut
subclass of: Plasmodium
definition: A Plasmodium that is formed after fertilization of the macrogamete by a microgamete in the midgut of the mosquito vector. This round form is the only diploid stage in the Plasmodium life cycle.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Ulrike Boehme
term tracker item: https://github.com/OPL-ontology/OPL/issues/2
ontology term requester: GeneDB

Plasmodium gamete stage
type: Class
equivalent class: Class
  intersection of: gamete stage
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium
subclass of: parasite lifecycle stage
subclass of: gamete stage
definition: A gamete stage in the Plasmodium lifecycle that occurs in the midgut of a mosquito vector.
term editor: Chris Stoeckert
term editor: Jie Zheng

Plasmodium macrogamete stage
type: Class
equivalent class: Class
  intersection of: macrogamete stage
  intersection of: Restriction
    on property: occurs in
    some values from: Anopheles midgut
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium
subclass of: macrogamete stage
subclass of: Plasmodium gamete stage
definition: A macrogamete stage in the Plasmodium lifecycle that occurs in the midgut of a mosquito vector.
term editor: Chris Stoeckert
term editor: Jie Zheng

Plasmodium microgamete stage
type: Class
equivalent class: Class
  intersection of: microgamete stage
  intersection of: Restriction
    on property: occurs in
    some values from: Anopheles midgut
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium
subclass of: microgamete stage
subclass of: Plasmodium gamete stage
definition: A microgamete stage in the Plasmodium lifecycle that occurs in the midgut of a mosquito vector.
term editor: Chris Stoeckert
term editor: Jie Zheng

Plasmodium gametocyte stage
type: Class
equivalent class: Class
  intersection of: gametocyte stage
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium
subclass of: gametocyte stage
subclass of: parasite lifecycle stage
definition: A gametocyte stage in the lifecycle of Plasmodium.
term editor: Chris Stoeckert
term editor: Jie Zheng

Plasmodium macrogametocyte stage
type: Class
equivalent class: Class
  intersection of: macrogametocyte stage
  intersection of: Restriction
    on property: occurs in
    some values from: Anopheles midgut
  intersection of: Restriction
    on property: occurs in
    some values from: Vertebrate erythrocyte
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium
subclass of: macrogametocyte stage
subclass of: Plasmodium gametocyte stage
definition: A macrogametocyte stage in the Plasmodium lifecycle that occurs either in the bloodstream of a vertebrate host or the midgut of a mosquito vector.
term editor: Chris Stoeckert
term editor: Jie Zheng

Plasmodium microgametocyte stage
type: Class
equivalent class: Class
  intersection of: microgametocyte stage
  intersection of: Restriction
    on property: occurs in
    some values from: Anopheles midgut
  intersection of: Restriction
    on property: occurs in
    some values from: Vertebrate erythrocyte
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium
subclass of: microgametocyte stage
subclass of: Plasmodium gametocyte stage
definition: A microgametocyte stage in the Plasmodium lifecycle that occurs either in the bloodstream of a vertebrate host or the midgut of a mosquito vector.
term editor: Chris Stoeckert
term editor: Jie Zheng

Plasmodium merozoite stage
type: Class
equivalent class: Class
  intersection of: merozoite stage
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium
subclass of: merozoite stage
definition: A merozoite stage in the Plasmodium lifecycle that occurs in the bloodstream or hepatocytes of a vertebrate host.
term editor: Chris Stoeckert
term editor: Jie Zheng

Plasmodium erythrocytic merozoite stage
type: Class
equivalent class: Class
  intersection of: erythrocytic merozoite stage
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium
subclass of: erythrocytic merozoite stage
subclass of: Plasmodium merozoite stage
definition: An erythrocytic merozoite stage in the Plasmodium lifecycle that occurs in the bloodstream of a vertebrate host.
term editor: Chris Stoeckert
term editor: Jie Zheng

Plasmodium hepatic merozoite stage
type: Class
equivalent class: Class
  intersection of: hepatic merozoite stage
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium
subclass of: hepatic merozoite stage
subclass of: Plasmodium merozoite stage
definition: A hepatic merozoite stage in the Plasmodium lifecycle that occurs in the hepatocyte of a vertebrate host.
term editor: Chris Stoeckert
term editor: Jie Zheng

Plasmodium oocyst stage
type: Class
equivalent class: Class
  intersection of: oocyst stage
  intersection of: Restriction
    on property: occurs in
    some values from: Anopheles midgut
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium
subclass of: oocyst stage
definition: An oocyst stage in the Plasmodium lifecycle that occurs on the hemocoel side of the midgut of a mosquito vector. During this stage Plasmodium ookinete invades and escapes midgut wall of mosquito and embed itself onto the exterior of the gut membrane and develop encysted zygote, called oocyst.
term editor: Chris Stoeckert
term editor: Jie Zheng

Plasmodium ookinete stage
type: Class
equivalent class: Class
  intersection of: ookinete stage
  intersection of: Restriction
    on property: occurs in
    some values from: Anopheles midgut
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium
subclass of: ookinete stage
definition: An ookinete stage in the Plasmodium lifecycle that occurs in the midgut of a mosquito vector and on the outside of the midgut.
term editor: Chris Stoeckert
term editor: Jie Zheng

Plasmodium schizont stage
type: Class
equivalent class: Class
  intersection of: schizont stage
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium
subclass of: schizont stage
definition: A schizont stage in the Plasmodium lifecycle that occurs in erythrocytes or in hepatocytes.
term editor: Chris Stoeckert
term editor: Jie Zheng

Plasmodium erythrocytic schizont stage
type: Class
equivalent class: Class
  intersection of: erythrocytic schizont stage
  intersection of: Restriction
    on property: occurs in
    some values from: Vertebrate erythrocyte
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium
subclass of: erythrocytic schizont stage
subclass of: Plasmodium schizont stage
definition: An erythrocytic schizont stage in the Plasmodium lifecycle that occurs in the infected erythrocytes of a vertebrate host.
term editor: Chris Stoeckert
term editor: Jie Zheng

Plasmodium hepatic schizont stage
type: Class
equivalent class: Class
  intersection of: hepatic schizont stage
  intersection of: Restriction
    on property: occurs in
    some values from: Vertebrate hepatocyte
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium
subclass of: hepatic schizont stage
subclass of: Plasmodium schizont stage
definition: A hepatic schizont stage in the Plasmodium lifecycle that occurs in the infected hepatocytes of a vertebrate host.
term editor: Chris Stoeckert
term editor: Jie Zheng

Plasmodium sporozoite stage
type: Class
equivalent class: Class
  intersection of: sporozoite stage
  intersection of: Restriction
    on property: occurs in
    some values from: Anopheles salivary gland
  intersection of: Restriction
    on property: occurs in
    some values from: Vertebrate blood
  intersection of: Restriction
    on property: occurs in
    some values from: Vertebrate hepatocyte
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium
subclass of: sporozoite stage
definition: A sporozoite stage in the Plasmodium lifecycle that occurs in the salivary glands of the mosquito and invades hepatocytes in the vertebrate host.
term editor: Chris Stoeckert
term editor: Jie Zheng

Plasmodium oocyst-derived sporozoite stage
type: Class
equivalent class: Class
  intersection of: oocyst-derived sporozoite stage
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium
subclass of: oocyst-derived sporozoite stage
definition: A sporozoite stage in the Plasmodium lifecycle that develops in oocysts of the mosquito midgut.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Omar harb

Plasmodium salivary gland-derived sporozoite stage
type: Class
equivalent class: Class
  intersection of: salivary gland-derived sporozoite stage
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium
subclass of: salivary gland-derived sporozoite stage
definition: A salivary gland-derived sporozoite stage in the Plasmodium lifecycle that occurs in the salivary glands of the mosquito and invades hepatocytes in the vertebrate host.
term editor: Chris Stoeckert
term editor: Jie Zheng
term editor: Omar harb

Plasmodium trophozoite stage
type: Class
equivalent class: Class
  intersection of: trophozoite stage
  intersection of: Restriction
    on property: occurs in
    some values from: Vertebrate erythrocyte
  intersection of: Restriction
    on property: occurs in
    some values from: Vertebrate hepatocyte
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium
subclass of: trophozoite stage
definition: A trophozoite stage in the Plasmodium lifecycle that occurs in a vertebrate host.
term editor: Chris Stoeckert
term editor: Jie Zheng

Plasmodium erythrocytic trophozoite stage
type: Class
equivalent class: Class
  intersection of: erythrocytic trophozoite stage
  intersection of: Restriction
    on property: occurs in
    some values from: Vertebrate erythrocyte
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium
subclass of: erythrocytic trophozoite stage
definition: An erythrocytic trophozoite stage in the Plasmodium life cycle that occurs in erythrocytes of a vertebrate host.
term editor: Chris Stoeckert
term editor: Jie Zheng

Plasmodium erythrocytic ring trophozoite stage
type: Class
equivalent class: Class
  intersection of: erythrocytic ring trophozoite stage
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium
subclass of: erythrocytic ring trophozoite stage
definition: An erythrocytic ring trophozoite stage in the Plasmodium life cycle that occurs in erythrocytes of a vertebrate host. During this stage some Plasmodium merozoites undergo asexual reproduction cycle in erythrocytes and form young trophozoites that are referred to as "ring form" due to their morphology.
term editor: Chris Stoeckert
term editor: Jie Zheng

Plasmodium hepatic trophozoite stage
type: Class
equivalent class: Class
  intersection of: hepatic trophozoite stage
  intersection of: Restriction
    on property: occurs in
    some values from: Vertebrate hepatocyte
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium
subclass of: hepatic trophozoite stage
definition: A hepatic trophozoite stage in the Plasmodium life cycle that occurs in hepatocytes of a vertebrate host.
term editor: Chris Stoeckert
term editor: Jie Zheng

Plasmodium zygote stage
type: Class
equivalent class: Class
  intersection of: zygote stage
  intersection of: Restriction
    on property: occurs in
    some values from: Anopheles midgut
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium
subclass of: parasite lifecycle stage
subclass of: zygote stage
definition: A zygote stage in the Plasmodium lifecycle that occurs in the midgut of the mosquito vector where a microgamete and a macrogamete fertilizes each other to produce a diploid cell.
term editor: Chris Stoeckert
term editor: Jie Zheng

Schistosoma haematobium adult worm stage
type: Class
equivalent class: Class
  intersection of: adult parasitic worm stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma haematobium
subclass of: Schistosoma haematobium worm stage
subclass of: adult parasitic worm stage
definition: An adult worm stage in the Schistosoma haematobium lifecycle.
term editor: Chris Stoeckert
term editor: Jie Zheng

Schistosoma japonicum adult worm stage
type: Class
equivalent class: Class
  intersection of: adult parasitic worm stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma japonicum
subclass of: Schistosoma japonicum worm stage
subclass of: adult parasitic worm stage
definition: An adult worm stage in the Schistosoma japonicum lifecycle.
term editor: Chris Stoeckert
term editor: Jie Zheng

Vertebrate blood
type: Class
equivalent class: Class
  intersection of: blood
  intersection of: Restriction
    on property: part of
    some values from: Vertebrata <vertebrates>
subclass of: blood
definition: Blood that is part of or originated from a vertebrate.
term editor: Jie Zheng
definition source: OPL

Vertebrate erythrocyte
type: Class
equivalent class: Class
  intersection of: erythrocyte
  intersection of: Restriction
    on property: part of
    some values from: Vertebrata <vertebrates>
subclass of: erythrocyte
definition: An erythrocyte that is a part of or originated from a vertebrate.
term editor: Jie Zheng
definition source: OPL

Vertebrate hepatocyte
type: Class
equivalent class: Class
  intersection of: hepatocyte
  intersection of: Restriction
    on property: part of
    some values from: Vertebrata <vertebrates>
subclass of: hepatocyte
definition: A hepatocyte that is a part of or originated from a vertebrate.
term editor: Jie Zheng
definition source: OPL

Mammalia cerebrospinal fluid
type: Class
equivalent class: Class
  intersection of: cerebrospinal fluid
  intersection of: Restriction
    on property: part of
    some values from: Mammalia
subclass of: cerebrospinal fluid
definition: Cerebrospinal fluid that is a part of or originated from a mammal.
term editor: Jie Zheng

Mammalia skin
type: Class
equivalent class: Class
  intersection of: skin of body
  intersection of: Restriction
    on property: part of
    some values from: Mammalia
subclass of: skin of body
definition: A skin that is a part of or originated from a mammalian body.
term editor: Jie Zheng

Mammalia liver
type: Class
equivalent class: Class
  intersection of: liver
  intersection of: Restriction
    on property: part of
    some values from: Mammalia
subclass of: liver
definition: A liver that is a part of or originated from a mammal (Mammalia).
term editor: Jie Zheng

Mammalia lung
type: Class
equivalent class: Class
  intersection of: lung
  intersection of: Restriction
    on property: part of
    some values from: Mammalia
subclass of: lung
definition: A lung that is a part of or originated from a mammal (Mammalia).
term editor: Jie Zheng

Mammalia mesenteric vein
type: Class
equivalent class: Class
  intersection of: mesenteric vein
  intersection of: Restriction
    on property: part of
    some values from: Mammalia
subclass of: mesenteric vein
definition: A mesenteric vein that is a part of or originated from a mammal (Mammalia).
term editor: Jie Zheng

Mammalia intestine
type: Class
equivalent class: Class
  intersection of: intestine
  intersection of: Restriction
    on property: part of
    some values from: Mammalia
subclass of: intestine
definition: An intestine that is a part of or originated from a mammal (Mammalia).
term editor: Jie Zheng

Schistosoma mansoni adult worm stage
type: Class
equivalent class: Class
  intersection of: adult parasitic worm stage
  intersection of: Restriction
    on property: in taxon
    some values from: Schistosoma mansoni
subclass of: Schistosoma mansoni worm stage
subclass of: adult parasitic worm stage
definition: An adult worm stage in the Schistosoma mansoni lifecycle.
term editor: Chris Stoeckert
term editor: Jie Zheng

Mammalia blood
type: Class
equivalent class: Class
  intersection of: blood
  intersection of: Restriction
    on property: part of
    some values from: Mammalia
subclass of: Vertebrate blood
definition: Blood that is part of or originated from a mammalia.
term editor: Jie Zheng

Mammalia macrophage
type: Class
equivalent class: Class
  intersection of: macrophage
  intersection of: Restriction
    on property: part of
    some values from: Mammalia
subclass of: macrophage
definition: A macrophage that is a part of or originated from a mammalia.
term editor: Jie Zheng

Trypanosomatida metacyclic stage
type: Class
equivalent class: Class
  intersection of: parasite lifecycle stage
  intersection of: Restriction
    on property: realizes
    some values from: infectious agent role
  intersection of: Restriction
    on property: in taxon
    some values from: Trypanosomatidae
subclass of: parasite lifecycle stage
definition: A parasite lifecycle stage of trypanosomatidae in which the organism is infectious and does not multiply.
term editor: Chris Stoeckert
term editor: Jie Zheng
alternative label: metacyclic stage
definition source: https://microbewiki.kenyon.edu/index.php/Trypanosome_Life_Cycle
definition source: https://web.stanford.edu/group/parasites/ParaSites2003/Leishmania/Leish%20Biology.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/9

Trypanosomatida procyclic stage
type: Class
equivalent class: Class
  intersection of: parasite lifecycle stage
  intersection of: Restriction
    on property: has part
    some values from: cell division
  intersection of: Restriction
    on property: occurs in
    some values from: Class
      union of: Phlebotominae midgut
      union of: Glossina midgut
  intersection of: Restriction
    on property: in taxon
    some values from: Trypanosomatidae
subclass of: parasite lifecycle stage
definition: A parasite lifecycle stage of trypanosomatidae in which the organism is in dividing form and it occurs in fly vector.
term editor: Achchuthan Shanmugasundram
term editor: Chris Stoeckert
term editor: Jie Zheng
alternative label: procyclic stage
definition source: VEuPathDB
term tracker item: https://github.com/OPL-ontology/OPL/issues/10

bradyzoite stage
type: Class
subclass of: parasite lifecycle stage
definition: A parasite life cycle stage found in the tissue cyst which replicates slowly within a parasitophorous vacuole within the host cell.
term editor: Jie Zheng
term editor: https://orcid.org/0000-0002-2825-0621 Paola Roncaglia
alternative label: bradyzoite
alternative label: cystozoite
definition source: https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/tachyzoite
term tracker item: https://github.com/OPL-ontology/OPL/issues/19
term tracker item: https://github.com/obophenotype/cell-ontology/issues/270
ontology term requester: Cell Ontology

tachyzoite stage
type: Class
subclass of: parasite lifecycle stage
definition: A parasite lifecycle stage that parasite replicates rapidly within the host cell.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7744739/

Plasmodium vivax ookinete
type: Class
subclass of: Plasmodium vivax
subclass of: Plasmodium ookinete
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium vivax ookinete stage
subclass of: Restriction
  on property: located in
  some values from: Anopheles midgut
definition: A Plasmodium vivax that is found in the midgut of a mosquito vector.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/dpdx/malaria/index.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Plasmodium vivax sporozoite
type: Class
subclass of: Plasmodium vivax
subclass of: Plasmodium sporozoite
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium vivax sporozoite stage
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens hepatocyte
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens blood
subclass of: Restriction
  on property: located in
  some values from: Anopheles salivary gland
definition: A Plasmodium vivax is formed in the oocyst. It migrates to and resides in the gut of the mosquito vector.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/dpdx/malaria/index.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Plasmodium vivax merozoite
type: Class
subclass of: Plasmodium vivax
subclass of: Plasmodium merozoite
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium vivax merozoite stage
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens erythrocyte
definition: A Plasmodium vivax that is found in the bloodstream of the human host and invades erythrocytes.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/dpdx/malaria/index.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Plasmodium vivax gametocyte
type: Class
subclass of: Plasmodium vivax
subclass of: Plasmodium gametocyte
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium vivax gametocyte stage
subclass of: Restriction
  on property: located in
  some values from: Anopheles midgut
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens erythrocyte
definition: A Plasmodium vivax that is located in the bloodstream of the human host.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/dpdx/malaria/index.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Plasmodium berghei sporazoite
type: Class
subclass of: Plasmodium berghei
subclass of: Plasmodium sporozoite
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium berghei sporazoite stage
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens hepatocyte
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens blood
subclass of: Restriction
  on property: located in
  some values from: Anopheles salivary gland
definition: A Plasmodium berghei is formed in the oocyst. It migrates to and resides in the gut of the mosquito vector.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/dpdx/malaria/index.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Plasmodium berghei merozoite
type: Class
subclass of: Plasmodium berghei
subclass of: Plasmodium merozoite
subclass of: Restriction
  on property: participates in
  some values from: Plasmodium berghei merozoite stage
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens erythrocyte
definition: A Plasmodium berghei that is found in the bloodstream of the human host and invades erythrocytes.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/dpdx/malaria/index.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Neospora caninum tachyzoite
type: Class
subclass of: Neospora caninum
subclass of: Restriction
  on property: participates in
  some values from: Neospora caninum tachyzoite stage
subclass of: Restriction
  on property: located in
  some values from: Canis
definition: A Neospora caninum that is found intracellular in the intermediate hosts in which asexual replication takes place.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890850/
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Eimeria maxima gametocyte
type: Class
subclass of: Eimeria maxima
subclass of: Restriction
  on property: participates in
  some values from: Eimeria maxima gametocyte stage
subclass of: Restriction
  on property: located in
  some values from: Gallus gallus erythrocyte
definition: An Eimeria maxima that is located in the bloodstream of the human host.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351014/
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Eimeria tenella sprozoite
type: Class
subclass of: Eimeria tenella
subclass of: Restriction
  on property: participates in
  some values from: Eimeria tenella sporozoite stage
subclass of: Restriction
  on property: located in
  some values from: Gallus gallus intestine
definition: An Eimeria tenella is formed in the oocyst. It migrates to and resides in the gut of the mosquito vector.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351014/
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Eimeria tenella oocyst
type: Class
subclass of: Eimeria tenella
subclass of: Restriction
  on property: participates in
  some values from: Eimeria tenella oocyst stage
subclass of: Restriction
  on property: located in
  some values from: Gallus gallus midgut
definition: An Eimeria tenella that oocyst is formed, found in the gut of the mosquito vector.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351014/
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Sarcocystis neurona merozoite
type: Class
subclass of: Sarcocystis neurona
subclass of: Restriction
  on property: participates in
  some values from: Sarcocystis neurona merozoite stage
subclass of: Restriction
  on property: located in
  some values from: Canis lupus familiaris erythrocyte
definition: A Sarcocystis neurona that is found in the bloodstream of the human host and invades erythrocytes.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.ncbi.nlm.nih.gov/books/NBK574577/
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Sarcocystis neurona sporozoite
type: Class
subclass of: Sarcocystis neurona
subclass of: Restriction
  on property: participates in
  some values from: Sarcocystis neurona sporozoite stage
subclass of: Restriction
  on property: located in
  some values from: Mammalia muscle tissue
definition: A Sarcocystis neurona is formed in the oocyst. It migrates to and resides in the gut of the mosquito vector.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.ncbi.nlm.nih.gov/books/NBK574577/
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Toxoplasma gondii tachyzoite
type: Class
subclass of: Toxoplasma gondii
subclass of: Restriction
  on property: participates in
  some values from: Toxoplasma gondii tachyzoite stage
subclass of: Restriction
  on property: located in
  some values from: Mammalia
definition: A Toxoplasma gondii that is formed in tissue in a host and replicates quickly. This replaces the previous term as .
term editor: Anthony Huffman
term editor: Jie Zheng
alternative label: Toxoplasma gondii trophozoite
definition source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC106833/
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Toxoplasma gondii bradyzoite
type: Class
subclass of: Toxoplasma gondii
subclass of: Restriction
  on property: participates in
  some values from: Toxoplasma gondii bradyzoite stage
subclass of: Restriction
  on property: located in
  some values from: Triatominae
definition: A Toxoplasma gondii that is formed in a tissue cyst of host, replicating slowly.
term editor: Anthony Huffman
term editor: Jie Zheng
alternative label: Toxoplasma gondii cystozoites
definition source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC106833/
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Toxoplasma gondii oocyst
type: Class
subclass of: Toxoplasma gondii
subclass of: Restriction
  on property: participates in
  some values from: Toxoplasma gondii oocysts stage
subclass of: Restriction
  on property: located in
  some values from: Triatominae midgut
definition: A Toxoplasma gondii that oocyst is formed, found in the gut of the bug vector.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC106833/
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Leishmania amazonensis promastigote
type: Class
subclass of: Leishmania amazonensis
subclass of: Restriction
  on property: participates in
  some values from: Leishmania amazonensis promastigote stage
subclass of: Restriction
  on property: located in
  some values from: Phlebotominae proboscis
subclass of: Restriction
  on property: located in
  some values from: Phlebotominae midgut
subclass of: Restriction
  on property: located in
  some values from: Mammalia macrophage
definition: A Leishmania amazonensis that occurs in the gut of a sandfly.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/parasites/leishmaniasis/biology.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Leishmania amazonensis amastigote
type: Class
subclass of: Leishmania amazonensis
subclass of: Restriction
  on property: participates in
  some values from: Leishmania amazonensis amastigote stage
subclass of: Restriction
  on property: located in
  some values from: Mammalia macrophage
definition: A Leishmania amazonensis that occurs in a mammal tissue.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/parasites/leishmaniasis/biology.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Leishmania donovani promastigote
type: Class
subclass of: Leishmania donovani
subclass of: Restriction
  on property: participates in
  some values from: Leishmania donovani promastigote stage
subclass of: Restriction
  on property: located in
  some values from: Phlebotominae proboscis
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens macrophage
subclass of: Restriction
  on property: located in
  some values from: Phlebotominae midgut
definition: A Leishmania donovani that is that occurs in the gut of a sandfly.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/parasites/leishmaniasis/biology.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Leishmania donovani amastigote
type: Class
subclass of: Leishmania donovani
subclass of: Restriction
  on property: participates in
  some values from: Leishmania donovani amastigote stage
subclass of: Restriction
  on property: located in
  some values from: Homo sapiens macrophage
definition: A Leishmania donovani that is that occurs in a mammal tissue.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/parasites/leishmaniasis/biology.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Leishmania infantum promastigote
type: Class
subclass of: Leishmania infantum
subclass of: Restriction
  on property: participates in
  some values from: Leishmania infantum promastigote stage
subclass of: Restriction
  on property: located in
  some values from: Phlebotominae proboscis
subclass of: Restriction
  on property: located in
  some values from: Phlebotominae midgut
subclass of: Restriction
  on property: located in
  some values from: Mammalia macrophage
definition: A Leishmania infantum that is that occurs in the gut of a sandfly.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/parasites/leishmaniasis/biology.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Leishmania infantum amastigote
type: Class
subclass of: Leishmania infantum
subclass of: Restriction
  on property: participates in
  some values from: Leishmania infantum amastigote stage
subclass of: Restriction
  on property: located in
  some values from: Mammalia macrophage
definition: A Leishmania infantum that is that occurs in a mammal tissue.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/dpdx/malaria/index.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Plasmodium vivax ookinete stage
type: Class
equivalent class: Class
  intersection of: ookinete stage
  intersection of: Restriction
    on property: occurs in
    some values from: Anopheles midgut
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium vivax
subclass of: Plasmodium ookinete stage
subclass of: Plasmodium vivax lifecycle stage
definition: An ookinete stage in Plasmodium vivax life cycle.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/dpdx/malaria/index.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Plasmodium vivax sporozoite stage
type: Class
equivalent class: Class
  intersection of: sporozoite stage
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens hepatocyte
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens blood
  intersection of: Restriction
    on property: occurs in
    some values from: Anopheles salivary gland
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium vivax
subclass of: Plasmodium sporozoite stage
subclass of: Plasmodium vivax lifecycle stage
definition: A sporozoite stage in Plasmodium vivax life cycle.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/dpdx/malaria/index.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Plasmodium vivax merozoite stage
type: Class
equivalent class: Class
  intersection of: merozoite stage
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens erythrocyte
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium vivax
subclass of: Plasmodium merozoite stage
subclass of: Plasmodium vivax lifecycle stage
definition: A merozoite stage in the Plasmodium vivax life cycle.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/dpdx/malaria/index.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Plasmodium vivax gametocyte stage
type: Class
equivalent class: Class
  intersection of: gametocyte stage
  intersection of: Restriction
    on property: occurs in
    some values from: Anopheles midgut
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens erythrocyte
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium vivax
subclass of: Plasmodium gametocyte stage
subclass of: Plasmodium vivax lifecycle stage
definition: A gametocyte stage in the Plasmodium vivax life cycle.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/dpdx/malaria/index.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Plasmodium berghei sporazoite stage
type: Class
equivalent class: Class
  intersection of: sporozoite stage
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens hepatocyte
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens blood
  intersection of: Restriction
    on property: occurs in
    some values from: Anopheles salivary gland
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium berghei
subclass of: Plasmodium sporozoite stage
subclass of: Plasmodium berghei lifecycle stage
definition: A sporozoite stage in the Plasmodium berghei life cycle.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/dpdx/malaria/index.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Plasmodium berghei merozoite stage
type: Class
equivalent class: Class
  intersection of: merozoite stage
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens erythrocyte
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium berghei
subclass of: Plasmodium merozoite stage
subclass of: Plasmodium berghei lifecycle stage
definition: A merozoite stage in the Plasmodium berghei life cycle.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/dpdx/malaria/index.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Neospora caninum tachyzoite stage
type: Class
equivalent class: Class
  intersection of: tachyzoite stage
  intersection of: Restriction
    on property: occurs in
    some values from: Canis
  intersection of: Restriction
    on property: in taxon
    some values from: Neospora caninum
subclass of: tachyzoite stage
subclass of: Neospora caninum lifecycle stage
definition: A tachyzoite stage in the Neospora caninum life cycle.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890850/
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Eimeria maxima gametocyte stage
type: Class
equivalent class: Class
  intersection of: gametocyte stage
  intersection of: Restriction
    on property: occurs in
    some values from: Gallus gallus erythrocyte
  intersection of: Restriction
    on property: in taxon
    some values from: Eimeria maxima
subclass of: gametocyte stage
subclass of: Eimeria maxima lifecycle stage
definition: A gametocyte stage in the Eimeria maxima life cycle.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351014/
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Eimeria tenella sporozoite stage
type: Class
equivalent class: Class
  intersection of: sporozoite stage
  intersection of: Restriction
    on property: occurs in
    some values from: Gallus gallus intestine
  intersection of: Restriction
    on property: in taxon
    some values from: Eimeria tenella
subclass of: sporozoite stage
subclass of: Eimeria tenella lifecycle stage
definition: A sporozoite stage in the Eimeria tenella life cycle.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238154/
definition source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351014/
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Eimeria tenella oocyst stage
type: Class
equivalent class: Class
  intersection of: oocyst stage
  intersection of: Restriction
    on property: occurs in
    some values from: Gallus gallus midgut
  intersection of: Restriction
    on property: in taxon
    some values from: Eimeria tenella
subclass of: oocyst stage
subclass of: Eimeria tenella lifecycle stage
definition: An oocysts stage in the Eimeria tenella life cycle.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351014/
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Sarcocystis neurona merozoite stage
type: Class
equivalent class: Class
  intersection of: merozoite stage
  intersection of: Restriction
    on property: occurs in
    some values from: Canis lupus familiaris erythrocyte
  intersection of: Restriction
    on property: in taxon
    some values from: Sarcocystis neurona
subclass of: merozoite stage
subclass of: Sarcocystis neurona lifecycle stage
definition: A merozoite stage in the Sarcocystis neurona life cycle.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://wcvm.usask.ca/learnaboutparasites/parasites/sarcocystis-neurona.php
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Sarcocystis neurona sporozoite stage
type: Class
equivalent class: Class
  intersection of: sporozoite stage
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia muscle tissue
  intersection of: Restriction
    on property: in taxon
    some values from: Sarcocystis neurona
subclass of: sporozoite stage
subclass of: Sarcocystis neurona lifecycle stage
definition: A sporozoite stage in the Sarcocystis neurona life cycle.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://pubmed.ncbi.nlm.nih.gov/15272465/
definition source: https://wcvm.usask.ca/learnaboutparasites/parasites/sarcocystis-neurona.php
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Toxoplasma gondii tachyzoite stage
type: Class
equivalent class: Class
  intersection of: tachyzoite stage
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia
  intersection of: Restriction
    on property: in taxon
    some values from: Toxoplasma gondii
subclass of: tachyzoite stage
subclass of: Toxoplasma gondii lifecycle stage
definition: A tachyzoite stage in the Toxoplasma gondii life cycle.
editor note: Tachyzoites can be found in various organs and tissues during the acute phase of Toxoplasma gondii infection, including lymph nodes, spleen, liver, lungs, and the central nervous system.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC106833/
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Toxoplasma gondii bradyzoite stage
type: Class
equivalent class: Class
  intersection of: bradyzoite stage
  intersection of: Restriction
    on property: occurs in
    some values from: Triatominae
  intersection of: Restriction
    on property: in taxon
    some values from: Toxoplasma gondii
subclass of: bradyzoite stage
subclass of: Toxoplasma gondii lifecycle stage
definition: A bradyzoite stage in the Toxoplasma gondii life cycle.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC106833/
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Toxoplasma gondii oocysts stage
type: Class
equivalent class: Class
  intersection of: oocyst stage
  intersection of: Restriction
    on property: occurs in
    some values from: Triatominae midgut
  intersection of: Restriction
    on property: in taxon
    some values from: Toxoplasma gondii
subclass of: oocyst stage
subclass of: Toxoplasma gondii lifecycle stage
definition: An oocysts stage in the Toxoplasma gondii life cycle.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC106833/
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Leishmania amazonensis promastigote stage
type: Class
equivalent class: Class
  intersection of: promastigote stage
  intersection of: Restriction
    on property: occurs in
    some values from: Phlebotominae proboscis
  intersection of: Restriction
    on property: occurs in
    some values from: Phlebotominae midgut
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia macrophage
  intersection of: Restriction
    on property: in taxon
    some values from: Leishmania amazonensis
subclass of: promastigote stage
subclass of: Leishmania amazonensis lifecycle stage
definition: A promastigote stage in the Leishmania amazonensis life cycle.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/parasites/leishmaniasis/biology.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Leishmania amazonensis amastigote stage
type: Class
equivalent class: Class
  intersection of: amastigote stage
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia macrophage
  intersection of: Restriction
    on property: in taxon
    some values from: Leishmania amazonensis
subclass of: amastigote stage
subclass of: Leishmania amazonensis lifecycle stage
definition: An amastigote stage in the Leishmania amazonensis life cycle.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/parasites/leishmaniasis/biology.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Leishmania donovani promastigote stage
type: Class
equivalent class: Class
  intersection of: promastigote stage
  intersection of: Restriction
    on property: occurs in
    some values from: Phlebotominae proboscis
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens macrophage
  intersection of: Restriction
    on property: occurs in
    some values from: Phlebotominae midgut
  intersection of: Restriction
    on property: in taxon
    some values from: Leishmania donovani
subclass of: promastigote stage
subclass of: Leishmania donovani lifecycle stage
definition: A promastigote stage in the Leishmania donovani life cycle.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/parasites/leishmaniasis/biology.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Leishmania donovani amastigote stage
type: Class
equivalent class: Class
  intersection of: amastigote stage
  intersection of: Restriction
    on property: occurs in
    some values from: Homo sapiens macrophage
  intersection of: Restriction
    on property: in taxon
    some values from: Leishmania donovani
subclass of: amastigote stage
subclass of: Leishmania donovani lifecycle stage
definition: An amastigote stage in the Leishmania donovani life cycle.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/parasites/leishmaniasis/biology.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Leishmania infantum promastigote stage
type: Class
equivalent class: Class
  intersection of: promastigote stage
  intersection of: Restriction
    on property: occurs in
    some values from: Phlebotominae proboscis
  intersection of: Restriction
    on property: occurs in
    some values from: Phlebotominae midgut
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia macrophage
  intersection of: Restriction
    on property: in taxon
    some values from: Leishmania infantum
subclass of: promastigote stage
subclass of: Leishmania infantum lifecycle stage
definition: A promastigote stage in the Leishmania infantum life cycle.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/parasites/leishmaniasis/biology.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Leishmania infantum amastigote stage
type: Class
equivalent class: Class
  intersection of: amastigote stage
  intersection of: Restriction
    on property: occurs in
    some values from: Mammalia macrophage
  intersection of: Restriction
    on property: in taxon
    some values from: Leishmania infantum
subclass of: amastigote stage
subclass of: Leishmania infantum lifecycle stage
definition: An amastigote stage in the Leishmania infantum life cycle.
term editor: Anthony Huffman
term editor: Jie Zheng
definition source: https://www.cdc.gov/parasites/leishmaniasis/biology.html
term tracker item: https://github.com/OPL-ontology/OPL/issues/21
ontology term requester: He Group

Gallus gallus erythrocyte
type: Class
equivalent class: Class
  intersection of: erythrocyte
  intersection of: Restriction
    on property: part of
    some values from: Gallus gallus
subclass of: Vertebrate erythrocyte
definition: An erythrocyte that is a part of or originated from a Gallus gallus.
term editor: Jie Zheng
definition source: He Group

Canis lupus familiaris erythrocyte
type: Class
equivalent class: Class
  intersection of: erythrocyte
  intersection of: Restriction
    on property: part of
    some values from: Canis lupus familiaris
subclass of: Vertebrate erythrocyte
definition: An erythrocyte that is a part of or originated from a Canis lupus familiaris.
term editor: Jie Zheng
definition source: He Group

Gallus gallus midgut
type: Class
equivalent class: Class
  intersection of: midgut
  intersection of: Restriction
    on property: part of
    some values from: Gallus gallus
subclass of: midgut
definition: A midgut that is a part of or originated from a Gallus gallus.
term editor: Jie Zheng
definition source: He Group

Gallus gallus intestine
type: Class
equivalent class: Class
  intersection of: intestine
  intersection of: Restriction
    on property: part of
    some values from: Gallus gallus
subclass of: intestine
definition: An intestine that is a part of or originated from a Gallus gallus.
term editor: Jie Zheng
definition source: He Group

Mammalia muscle tissue
type: Class
equivalent class: Class
  intersection of: muscle tissue
  intersection of: Restriction
    on property: part of
    some values from: Mammalia
subclass of: muscle tissue
definition: A muscle tissue that is a part of or originated from a Mammalia.
term editor: Jie Zheng
definition source: He Group

Triatominae intestine
type: Class
equivalent class: Class
  intersection of: intestine
  intersection of: Restriction
    on property: part of
    some values from: Triatominae
subclass of: intestine
definition: An intestine that is a part of or originated from a Triatominae.
term editor: Jie Zheng
definition source: He Group

Plasmodium vivax lifecycle stage
type: Class
equivalent class: Class
  intersection of: parasite lifecycle stage
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium vivax
subclass of: parasite lifecycle stage
definition: A lifecycle stage of Plasmodium vivax.
term editor: Jie Zheng
definition source: He Group

Plasmodium berghei lifecycle stage
type: Class
equivalent class: Class
  intersection of: parasite lifecycle stage
  intersection of: Restriction
    on property: in taxon
    some values from: Plasmodium berghei
subclass of: parasite lifecycle stage
definition: A lifecycle stage of Plasmodium berghei.
term editor: Jie Zheng
definition source: He Group

Neospora caninum lifecycle stage
type: Class
equivalent class: Class
  intersection of: parasite lifecycle stage
  intersection of: Restriction
    on property: in taxon
    some values from: Neospora caninum
subclass of: parasite lifecycle stage
definition: A lifecycle stage of Neospora caninum.
term editor: Jie Zheng
definition source: He Group

Eimeria maxima lifecycle stage
type: Class
equivalent class: Class
  intersection of: parasite lifecycle stage
  intersection of: Restriction
    on property: in taxon
    some values from: Eimeria maxima
subclass of: parasite lifecycle stage
definition: A lifecycle stage of Eimeria maxima.
term editor: Jie Zheng
definition source: He Group

Eimeria tenella lifecycle stage
type: Class
equivalent class: Class
  intersection of: parasite lifecycle stage
  intersection of: Restriction
    on property: in taxon
    some values from: Eimeria tenella
subclass of: parasite lifecycle stage
definition: A lifecycle stage of Eimeria tenella.
term editor: Jie Zheng
definition source: He Group

Sarcocystis neurona lifecycle stage
type: Class
equivalent class: Class
  intersection of: parasite lifecycle stage
  intersection of: Restriction
    on property: in taxon
    some values from: Sarcocystis neurona
subclass of: parasite lifecycle stage
definition: A lifecycle stage of Sarcocystis neurona.
term editor: Jie Zheng
definition source: He Group

Toxoplasma gondii lifecycle stage
type: Class
equivalent class: Class
  intersection of: parasite lifecycle stage
  intersection of: Restriction
    on property: in taxon
    some values from: Toxoplasma gondii
subclass of: parasite lifecycle stage
definition: A lifecycle stage of Toxoplasma gondii.
term editor: Jie Zheng
definition source: He Group

Leishmania amazonensis lifecycle stage
type: Class
equivalent class: Class
  intersection of: parasite lifecycle stage
  intersection of: Restriction
    on property: in taxon
    some values from: Leishmania amazonensis
subclass of: parasite lifecycle stage
definition: A lifecycle stage of Leishmania amazonensis.
term editor: Jie Zheng
definition source: He Group

Leishmania donovani lifecycle stage
type: Class
equivalent class: Class
  intersection of: parasite lifecycle stage
  intersection of: Restriction
    on property: in taxon
    some values from: Leishmania donovani
subclass of: parasite lifecycle stage
definition: A lifecycle stage of Leishmania donovani.
term editor: Jie Zheng
definition source: He Group

Leishmania infantum lifecycle stage
type: Class
equivalent class: Class
  intersection of: parasite lifecycle stage
  intersection of: Restriction
    on property: in taxon
    some values from: Leishmania infantum
subclass of: parasite lifecycle stage
definition: A lifecycle stage of Leishmania infantum.
term editor: Jie Zheng
definition source: He Group

ureter
type: Class
subclass of: material anatomical entity
definition: Muscular duct that propels urine from the kidneys to the urinary bladder, or related organs.
imported from: uberon.owl

life cycle stage
type: Class
subclass of: process
definition: A spatiotemporal region encompassing some part of the life cycle of an organism.
imported from: uberon.owl

zygote stage
type: Class
subclass of: life cycle stage
definition: A stage at which the organism is a single cell produced by means of sexual reproduction.
imported from: uberon.owl

intestine
type: Class
subclass of: material anatomical entity
definition: Segment of the alimentary canal extending from the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine.
imported from: uberon.owl

blood
type: Class
subclass of: material anatomical entity
definition: A fluid that is composed of blood plasma and erythrocytes.
imported from: uberon.owl

material anatomical entity
type: Class
subclass of: material entity
definition: Anatomical entity that has mass.
imported from: uberon.owl

saliva-secreting gland
type: Class
subclass of: material anatomical entity
definition: Saliva-secreting exocrine glands of the oral cavity[GO].
imported from: uberon.owl

midgut
type: Class
subclass of: material anatomical entity
definition: Middle subdivision of a digestive tract[CJM]. In vertebrates: The middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine[GO].
imported from: uberon.owl

hindgut
type: Class
subclass of: material anatomical entity
definition: The caudalmost subdivision of a digestive tract.
imported from: uberon.owl

urinary bladder
type: Class
subclass of: material anatomical entity
definition: Distensible musculomembranous organ situated in the anterior part of the pelvic cavity in which urine collects before excretion[MP].
imported from: uberon.owl

cerebrospinal fluid
type: Class
subclass of: material anatomical entity
definition: A clear, colorless, bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord.
imported from: uberon.owl

lung
type: Class
subclass of: material anatomical entity
definition: Respiration organ that develops as an outpocketing of the esophagus.
imported from: uberon.owl

skin of body
type: Class
subclass of: material anatomical entity
definition: The organ covering the body that consists of the dermis and epidermis.
imported from: uberon.owl

liver
type: Class
subclass of: material anatomical entity
definition: An exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO].
imported from: uberon.owl

muscle tissue
type: Class
subclass of: material anatomical entity
definition: Muscle tissue is a contractile tissue made up of actin and myosin fibers[GO].
imported from: uberon.owl

mesenteric vein
type: Class
subclass of: material anatomical entity
definition: A vein that returns blood from the intestines.
imported from: uberon.owl

Obsolete Class
type: Class
subclass of: Thing

example to be eventually removed
type: NamedIndividual
type: curation status specification
editor preferred term: example to be eventually removed

failed exploratory term
type: NamedIndividual
type: obsolescence reason specification
editor preferred term: failed exploratory term
definition: The term was used in an attempt to structure part of the ontology but in retrospect failed to do a good job
term editor: Person:Alan Ruttenberg

metadata complete
type: NamedIndividual
type: curation status specification
editor preferred term: metadata complete
definition: Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete.

organizational term
type: NamedIndividual
type: curation status specification
editor preferred term: organizational term
definition: Term created to ease viewing/sort terms for development purpose, and will not be included in a release

ready for release
type: NamedIndividual
type: curation status specification
editor preferred term: ready for release
definition: Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking "ready_for_release" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release. Those classes deemed "ready_for_release" will also derived from a chain of ancestor classes that are also "ready_for_release."

metadata incomplete
type: NamedIndividual
type: curation status specification
editor preferred term: metadata incomplete
definition: Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors.

uncurated
type: NamedIndividual
type: curation status specification
editor preferred term: uncurated
definition: Nothing done yet beyond assigning a unique class ID and proposing a preferred term.

pending final vetting
type: NamedIndividual
type: curation status specification
editor preferred term: pending final vetting
definition: All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the term editor.

obsolete_core
type: NamedIndividual
definition: Core is an instance of a grouping of terms from an ontology or ontologies. It is used by the ontology to identify main classes.
term editor: PERSON: Alan Ruttenberg
term editor: PERSON: Melanie Courtot
has obsolescence reason: placeholder removed
deprecated: true

placeholder removed
type: NamedIndividual
type: obsolescence reason specification
editor preferred term: placeholder removed

terms merged
type: NamedIndividual
type: obsolescence reason specification
editor preferred term: terms merged
editor note: An editor note should explain what were the merged terms and the reason for the merge.

term imported
type: NamedIndividual
type: obsolescence reason specification
editor preferred term: term imported
editor note: This is to be used when the original term has been replaced by a term imported from an other ontology. An editor note should indicate what is the URI of the new term to use.

term split
type: NamedIndividual
type: obsolescence reason specification
editor preferred term: term split
editor note: This is to be used when a term has been split in two or more new terms. An editor note should indicate the reason for the split and indicate the URIs of the new terms created.

universal
type: NamedIndividual
type: denotator type
editor preferred term: universal
editor note: Hard to give a definition for. Intuitively a "natural kind" rather than a collection of any old things, which a class is able to be, formally. At the meta level, universals are defined as positives, are disjoint with their siblings, have single asserted parents.
term editor: Alan Ruttenberg
definition source: A Formal Theory of Substances, Qualities, and Universals, http://ontology.buffalo.edu/bfo/SQU.pdf

defined class
type: NamedIndividual
type: denotator type
editor preferred term: defined class
definition: A defined class is a class that is defined by a set of logically necessary and sufficient conditions but is not a universal
editor note: "definitions", in some readings, always are given by necessary and sufficient conditions. So one must be careful (and this is difficult sometimes) to distinguish between defined classes and universal.
term editor: Alan Ruttenberg

named class expression
type: NamedIndividual
type: denotator type
editor preferred term: named class expression
definition: A named class expression is a logical expression that is given a name. The name can be used in place of the expression.
editor note: named class expressions are used in order to have more concise logical definition but their extensions may not be interesting classes on their own. In languages such as OWL, with no provisions for macros, these show up as actuall classes. Tools may with to not show them as such, and to replace uses of the macros with their expansions
term editor: Alan Ruttenberg

to be replaced with external ontology term
type: NamedIndividual
type: curation status specification
editor preferred term: to be replaced with external ontology term
definition: Terms with this status should eventually replaced with a term from another ontology.
term editor: Alan Ruttenberg
definition source: group:OBI

requires discussion
type: NamedIndividual
type: curation status specification
editor preferred term: requires discussion
definition: A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues.
term editor: Alan Ruttenberg
definition source: group:OBI

out of scope
type: NamedIndividual
type: obsolescence reason specification
definition: The term was added to the ontology on the assumption it was in scope, but it turned out later that it was not.
editor note: This obsolesence reason should be used conservatively. Typical valid examples are: un-necessary grouping classes in disease ontologies, a phenotype term added on the assumption it was a disease.
term editor: http://orcid.org/0000-0001-5208-3432
term tracker item: https://github.com/information-artifact-ontology/ontology-metadata/issues/77
ontology term requester: https://orcid.org/0000-0001-5208-3432