{
  "Version": 78,
  "Individuals": [
    {
      "Name": "Grahnen_1979",
      "Seed": 638660156,
      "OriginData": {
        "CalculationMethods": [
          "SurfaceAreaPlsInt_VAR1",
          "Body surface area - Mosteller"
        ],
        "Species": "Human",
        "Population": "European_ICRP_2002",
        "Gender": "MALE",
        "Age": {
          "Value": 23.5,
          "Unit": "year(s)"
        }
      },
      "Parameters": [
        {
          "Path": "MATE1|Reference concentration",
          "Value": 0.13257,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "MATE1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "MATE1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|Reference concentration",
          "Value": 0.0917,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OAT3|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|Reference concentration",
          "Value": 0.16465,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OCT1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "Organism|Bone|Intracellular|OCT1|Relative expression",
          "Value": 0.02439093
        },
        {
          "Path": "Organism|Brain|Intracellular|OAT3|Relative expression",
          "Value": 0.00061613691932
        },
        {
          "Path": "Organism|Brain|Intracellular|OCT1|Relative expression",
          "Value": 0.0135293069
        },
        {
          "Path": "Organism|Gonads|Intracellular|OCT1|Relative expression",
          "Value": 0.0035130263768
        },
        {
          "Path": "Organism|Heart|Intracellular|OCT1|Relative expression",
          "Value": 0.0067231912312
        },
        {
          "Path": "Organism|Kidney|Intracellular|MATE1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OAT3|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OCT1|Relative expression",
          "Value": 0.031737522
        },
        {
          "Path": "Organism|LargeIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0315629708
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Lung|Intracellular|OCT1|Relative expression",
          "Value": 0.0146483426
        },
        {
          "Path": "Organism|Muscle|Intracellular|OCT1|Relative expression",
          "Value": 0.0407525944
        },
        {
          "Path": "Organism|Pancreas|Intracellular|OCT1|Relative expression",
          "Value": 0.0065687827703
        },
        {
          "Path": "Organism|Skin|Intracellular|OCT1|Relative expression",
          "Value": 0.0119814482
        },
        {
          "Path": "Organism|SmallIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|Duodenum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|Spleen|Intracellular|OCT1|Relative expression",
          "Value": 0.0050234148247
        },
        {
          "Path": "Organism|Stomach|Intracellular|OCT1|Relative expression",
          "Value": 0.0093257582694
        }
      ],
      "Molecules": [
        {
          "Name": "OCT1",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "OAT3",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "MATE1",
          "Type": "Transporter",
          "TransportType": "Efflux",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainInterstitialToPlasma",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainTissueToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "EffluxBloodCellsToPlasma"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "EffluxInterstitialToPlasma"
            }
          ]
        }
      ]
    },
    {
      "Name": "Tiseo_1998",
      "Seed": 698841312,
      "OriginData": {
        "CalculationMethods": [
          "SurfaceAreaPlsInt_VAR1",
          "Body surface area - Mosteller"
        ],
        "Species": "Human",
        "Population": "WhiteAmerican_NHANES_1997",
        "Gender": "MALE",
        "Age": {
          "Value": 28.7,
          "Unit": "year(s)"
        },
        "Weight": {
          "Value": 75.5,
          "Unit": "kg"
        },
        "Height": {
          "Value": 179.4,
          "Unit": "cm"
        }
      },
      "Parameters": [
        {
          "Path": "MATE1|Reference concentration",
          "Value": 0.13257,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "MATE1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "MATE1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|Reference concentration",
          "Value": 0.0917,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OAT3|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|Reference concentration",
          "Value": 0.16465,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OCT1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "Organism|Bone|Intracellular|OCT1|Relative expression",
          "Value": 0.02439093
        },
        {
          "Path": "Organism|Brain|Intracellular|OAT3|Relative expression",
          "Value": 0.00061613691932
        },
        {
          "Path": "Organism|Brain|Intracellular|OCT1|Relative expression",
          "Value": 0.0135293069
        },
        {
          "Path": "Organism|Gonads|Intracellular|OCT1|Relative expression",
          "Value": 0.0035130263768
        },
        {
          "Path": "Organism|Heart|Intracellular|OCT1|Relative expression",
          "Value": 0.0067231912312
        },
        {
          "Path": "Organism|Kidney|Intracellular|MATE1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OAT3|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OCT1|Relative expression",
          "Value": 0.031737522
        },
        {
          "Path": "Organism|LargeIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0315629708
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Lung|Intracellular|OCT1|Relative expression",
          "Value": 0.0146483426
        },
        {
          "Path": "Organism|Muscle|Intracellular|OCT1|Relative expression",
          "Value": 0.0407525944
        },
        {
          "Path": "Organism|Pancreas|Intracellular|OCT1|Relative expression",
          "Value": 0.0065687827703
        },
        {
          "Path": "Organism|Skin|Intracellular|OCT1|Relative expression",
          "Value": 0.0119814482
        },
        {
          "Path": "Organism|SmallIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|Duodenum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|Spleen|Intracellular|OCT1|Relative expression",
          "Value": 0.0050234148247
        },
        {
          "Path": "Organism|Stomach|Intracellular|OCT1|Relative expression",
          "Value": 0.0093257582694
        }
      ],
      "Molecules": [
        {
          "Name": "OCT1",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "OAT3",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "MATE1",
          "Type": "Transporter",
          "TransportType": "Efflux",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainInterstitialToPlasma",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainTissueToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "EffluxBloodCellsToPlasma"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "EffluxInterstitialToPlasma"
            }
          ]
        }
      ]
    },
    {
      "Name": "Barbhaiya_1995",
      "Seed": 700622171,
      "OriginData": {
        "CalculationMethods": [
          "SurfaceAreaPlsInt_VAR1",
          "Body surface area - Mosteller"
        ],
        "Species": "Human",
        "Population": "WhiteAmerican_NHANES_1997",
        "Gender": "MALE",
        "Age": {
          "Value": 27.0,
          "Unit": "year(s)"
        },
        "Weight": {
          "Value": 76.0,
          "Unit": "kg"
        },
        "Height": {
          "Value": 179.0,
          "Unit": "cm"
        }
      },
      "Parameters": [
        {
          "Path": "MATE1|Reference concentration",
          "Value": 0.13257,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "MATE1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "MATE1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|Reference concentration",
          "Value": 0.0917,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OAT3|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|Reference concentration",
          "Value": 0.16465,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OCT1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "Organism|Bone|Intracellular|OCT1|Relative expression",
          "Value": 0.02439093
        },
        {
          "Path": "Organism|Brain|Intracellular|OAT3|Relative expression",
          "Value": 0.00061613691932
        },
        {
          "Path": "Organism|Brain|Intracellular|OCT1|Relative expression",
          "Value": 0.0135293069
        },
        {
          "Path": "Organism|Gonads|Intracellular|OCT1|Relative expression",
          "Value": 0.0035130263768
        },
        {
          "Path": "Organism|Heart|Intracellular|OCT1|Relative expression",
          "Value": 0.0067231912312
        },
        {
          "Path": "Organism|Kidney|Intracellular|MATE1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OAT3|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OCT1|Relative expression",
          "Value": 0.031737522
        },
        {
          "Path": "Organism|LargeIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0315629708
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Lung|Intracellular|OCT1|Relative expression",
          "Value": 0.0146483426
        },
        {
          "Path": "Organism|Muscle|Intracellular|OCT1|Relative expression",
          "Value": 0.0407525944
        },
        {
          "Path": "Organism|Pancreas|Intracellular|OCT1|Relative expression",
          "Value": 0.0065687827703
        },
        {
          "Path": "Organism|Skin|Intracellular|OCT1|Relative expression",
          "Value": 0.0119814482
        },
        {
          "Path": "Organism|SmallIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|Duodenum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|Spleen|Intracellular|OCT1|Relative expression",
          "Value": 0.0050234148247
        },
        {
          "Path": "Organism|Stomach|Intracellular|OCT1|Relative expression",
          "Value": 0.0093257582694
        }
      ],
      "Molecules": [
        {
          "Name": "OCT1",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "OAT3",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "MATE1",
          "Type": "Transporter",
          "TransportType": "Efflux",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainInterstitialToPlasma",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainTissueToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "EffluxBloodCellsToPlasma"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "EffluxInterstitialToPlasma"
            }
          ]
        }
      ]
    },
    {
      "Name": "Bodemar_1979",
      "Seed": 700784765,
      "OriginData": {
        "CalculationMethods": [
          "SurfaceAreaPlsInt_VAR1",
          "Body surface area - Mosteller"
        ],
        "Species": "Human",
        "Population": "European_ICRP_2002",
        "Gender": "MALE",
        "Age": {
          "Value": 55.0,
          "Unit": "year(s)"
        }
      },
      "Parameters": [
        {
          "Path": "MATE1|Reference concentration",
          "Value": 0.13257,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "MATE1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "MATE1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|Reference concentration",
          "Value": 0.0917,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OAT3|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|Reference concentration",
          "Value": 0.16465,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OCT1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "Organism|Bone|Intracellular|OCT1|Relative expression",
          "Value": 0.02439093
        },
        {
          "Path": "Organism|Brain|Intracellular|OAT3|Relative expression",
          "Value": 0.00061613691932
        },
        {
          "Path": "Organism|Brain|Intracellular|OCT1|Relative expression",
          "Value": 0.0135293069
        },
        {
          "Path": "Organism|Gonads|Intracellular|OCT1|Relative expression",
          "Value": 0.0035130263768
        },
        {
          "Path": "Organism|Heart|Intracellular|OCT1|Relative expression",
          "Value": 0.0067231912312
        },
        {
          "Path": "Organism|Kidney|Intracellular|MATE1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OAT3|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OCT1|Relative expression",
          "Value": 0.031737522
        },
        {
          "Path": "Organism|LargeIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0315629708
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Lung|Intracellular|OCT1|Relative expression",
          "Value": 0.0146483426
        },
        {
          "Path": "Organism|Muscle|Intracellular|OCT1|Relative expression",
          "Value": 0.0407525944
        },
        {
          "Path": "Organism|Pancreas|Intracellular|OCT1|Relative expression",
          "Value": 0.0065687827703
        },
        {
          "Path": "Organism|Skin|Intracellular|OCT1|Relative expression",
          "Value": 0.0119814482
        },
        {
          "Path": "Organism|SmallIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|Duodenum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|Spleen|Intracellular|OCT1|Relative expression",
          "Value": 0.0050234148247
        },
        {
          "Path": "Organism|Stomach|Intracellular|OCT1|Relative expression",
          "Value": 0.0093257582694
        }
      ],
      "Molecules": [
        {
          "Name": "OCT1",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "OAT3",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "MATE1",
          "Type": "Transporter",
          "TransportType": "Efflux",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainInterstitialToPlasma",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainTissueToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "EffluxBloodCellsToPlasma"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "EffluxInterstitialToPlasma"
            }
          ]
        }
      ]
    },
    {
      "Name": "Bodemar_1981",
      "Seed": 700858984,
      "OriginData": {
        "CalculationMethods": [
          "SurfaceAreaPlsInt_VAR1",
          "Body surface area - Mosteller"
        ],
        "Species": "Human",
        "Population": "European_ICRP_2002",
        "Gender": "MALE",
        "Age": {
          "Value": 40.0,
          "Unit": "year(s)"
        },
        "Weight": {
          "Value": 72.0,
          "Unit": "kg"
        }
      },
      "Parameters": [
        {
          "Path": "MATE1|Reference concentration",
          "Value": 0.13257,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "MATE1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "MATE1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|Reference concentration",
          "Value": 0.0917,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OAT3|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|Reference concentration",
          "Value": 0.16465,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OCT1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "Organism|Bone|Intracellular|OCT1|Relative expression",
          "Value": 0.02439093
        },
        {
          "Path": "Organism|Brain|Intracellular|OAT3|Relative expression",
          "Value": 0.00061613691932
        },
        {
          "Path": "Organism|Brain|Intracellular|OCT1|Relative expression",
          "Value": 0.0135293069
        },
        {
          "Path": "Organism|Gonads|Intracellular|OCT1|Relative expression",
          "Value": 0.0035130263768
        },
        {
          "Path": "Organism|Heart|Intracellular|OCT1|Relative expression",
          "Value": 0.0067231912312
        },
        {
          "Path": "Organism|Kidney|Intracellular|MATE1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OAT3|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OCT1|Relative expression",
          "Value": 0.031737522
        },
        {
          "Path": "Organism|LargeIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0315629708
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Lung|Intracellular|OCT1|Relative expression",
          "Value": 0.0146483426
        },
        {
          "Path": "Organism|Muscle|Intracellular|OCT1|Relative expression",
          "Value": 0.0407525944
        },
        {
          "Path": "Organism|Pancreas|Intracellular|OCT1|Relative expression",
          "Value": 0.0065687827703
        },
        {
          "Path": "Organism|Skin|Intracellular|OCT1|Relative expression",
          "Value": 0.0119814482
        },
        {
          "Path": "Organism|SmallIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|Duodenum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|Spleen|Intracellular|OCT1|Relative expression",
          "Value": 0.0050234148247
        },
        {
          "Path": "Organism|Stomach|Intracellular|OCT1|Relative expression",
          "Value": 0.0093257582694
        }
      ],
      "Molecules": [
        {
          "Name": "OCT1",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "OAT3",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "MATE1",
          "Type": "Transporter",
          "TransportType": "Efflux",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainInterstitialToPlasma",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainTissueToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "EffluxBloodCellsToPlasma"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "EffluxInterstitialToPlasma"
            }
          ]
        }
      ]
    },
    {
      "Name": "Burland_1975",
      "Seed": 700904750,
      "OriginData": {
        "CalculationMethods": [
          "SurfaceAreaPlsInt_VAR1",
          "Body surface area - Mosteller"
        ],
        "Species": "Human",
        "Population": "European_ICRP_2002",
        "Gender": "MALE",
        "Age": {
          "Value": 33.5,
          "Unit": "year(s)"
        }
      },
      "Parameters": [
        {
          "Path": "MATE1|Reference concentration",
          "Value": 0.13257,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "MATE1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "MATE1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|Reference concentration",
          "Value": 0.0917,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OAT3|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|Reference concentration",
          "Value": 0.16465,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OCT1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "Organism|Bone|Intracellular|OCT1|Relative expression",
          "Value": 0.02439093
        },
        {
          "Path": "Organism|Brain|Intracellular|OAT3|Relative expression",
          "Value": 0.00061613691932
        },
        {
          "Path": "Organism|Brain|Intracellular|OCT1|Relative expression",
          "Value": 0.0135293069
        },
        {
          "Path": "Organism|Gonads|Intracellular|OCT1|Relative expression",
          "Value": 0.0035130263768
        },
        {
          "Path": "Organism|Heart|Intracellular|OCT1|Relative expression",
          "Value": 0.0067231912312
        },
        {
          "Path": "Organism|Kidney|Intracellular|MATE1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OAT3|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OCT1|Relative expression",
          "Value": 0.031737522
        },
        {
          "Path": "Organism|LargeIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0315629708
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Lung|Intracellular|OCT1|Relative expression",
          "Value": 0.0146483426
        },
        {
          "Path": "Organism|Muscle|Intracellular|OCT1|Relative expression",
          "Value": 0.0407525944
        },
        {
          "Path": "Organism|Pancreas|Intracellular|OCT1|Relative expression",
          "Value": 0.0065687827703
        },
        {
          "Path": "Organism|Skin|Intracellular|OCT1|Relative expression",
          "Value": 0.0119814482
        },
        {
          "Path": "Organism|SmallIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|Duodenum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|Spleen|Intracellular|OCT1|Relative expression",
          "Value": 0.0050234148247
        },
        {
          "Path": "Organism|Stomach|Intracellular|OCT1|Relative expression",
          "Value": 0.0093257582694
        }
      ],
      "Molecules": [
        {
          "Name": "OCT1",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "OAT3",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "MATE1",
          "Type": "Transporter",
          "TransportType": "Efflux",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainInterstitialToPlasma",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainTissueToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "EffluxBloodCellsToPlasma"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "EffluxInterstitialToPlasma"
            }
          ]
        }
      ]
    },
    {
      "Name": "D'Angio_1986",
      "Seed": 721970500,
      "OriginData": {
        "CalculationMethods": [
          "SurfaceAreaPlsInt_VAR1",
          "Body surface area - Mosteller"
        ],
        "Species": "Human",
        "Population": "WhiteAmerican_NHANES_1997",
        "Gender": "MALE",
        "Age": {
          "Value": 34.5,
          "Unit": "year(s)"
        }
      },
      "Parameters": [
        {
          "Path": "MATE1|Reference concentration",
          "Value": 0.13257,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "MATE1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "MATE1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|Reference concentration",
          "Value": 0.0917,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OAT3|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|Reference concentration",
          "Value": 0.16465,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OCT1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "Organism|Bone|Intracellular|OCT1|Relative expression",
          "Value": 0.02439093
        },
        {
          "Path": "Organism|Brain|Intracellular|OAT3|Relative expression",
          "Value": 0.00061613691932
        },
        {
          "Path": "Organism|Brain|Intracellular|OCT1|Relative expression",
          "Value": 0.0135293069
        },
        {
          "Path": "Organism|Gonads|Intracellular|OCT1|Relative expression",
          "Value": 0.0035130263768
        },
        {
          "Path": "Organism|Heart|Intracellular|OCT1|Relative expression",
          "Value": 0.0067231912312
        },
        {
          "Path": "Organism|Kidney|Intracellular|MATE1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OAT3|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OCT1|Relative expression",
          "Value": 0.031737522
        },
        {
          "Path": "Organism|LargeIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0315629708
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Lung|Intracellular|OCT1|Relative expression",
          "Value": 0.0146483426
        },
        {
          "Path": "Organism|Muscle|Intracellular|OCT1|Relative expression",
          "Value": 0.0407525944
        },
        {
          "Path": "Organism|Pancreas|Intracellular|OCT1|Relative expression",
          "Value": 0.0065687827703
        },
        {
          "Path": "Organism|Skin|Intracellular|OCT1|Relative expression",
          "Value": 0.0119814482
        },
        {
          "Path": "Organism|SmallIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|Duodenum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|Spleen|Intracellular|OCT1|Relative expression",
          "Value": 0.0050234148247
        },
        {
          "Path": "Organism|Stomach|Intracellular|OCT1|Relative expression",
          "Value": 0.0093257582694
        }
      ],
      "Molecules": [
        {
          "Name": "OCT1",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "OAT3",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "MATE1",
          "Type": "Transporter",
          "TransportType": "Efflux",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainInterstitialToPlasma",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainTissueToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "EffluxBloodCellsToPlasma"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "EffluxInterstitialToPlasma"
            }
          ]
        }
      ]
    },
    {
      "Name": "Kanto_1981",
      "Seed": 722043671,
      "OriginData": {
        "CalculationMethods": [
          "SurfaceAreaPlsInt_VAR1",
          "Body surface area - Mosteller"
        ],
        "Species": "Human",
        "Population": "European_ICRP_2002",
        "Gender": "MALE",
        "Age": {
          "Value": 21.0,
          "Unit": "year(s)"
        },
        "Weight": {
          "Value": 61.0,
          "Unit": "kg"
        }
      },
      "Parameters": [
        {
          "Path": "MATE1|Reference concentration",
          "Value": 0.13257,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "MATE1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "MATE1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|Reference concentration",
          "Value": 0.0917,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OAT3|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|Reference concentration",
          "Value": 0.16465,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OCT1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "Organism|Bone|Intracellular|OCT1|Relative expression",
          "Value": 0.02439093
        },
        {
          "Path": "Organism|Brain|Intracellular|OAT3|Relative expression",
          "Value": 0.00061613691932
        },
        {
          "Path": "Organism|Brain|Intracellular|OCT1|Relative expression",
          "Value": 0.0135293069
        },
        {
          "Path": "Organism|Gonads|Intracellular|OCT1|Relative expression",
          "Value": 0.0035130263768
        },
        {
          "Path": "Organism|Heart|Intracellular|OCT1|Relative expression",
          "Value": 0.0067231912312
        },
        {
          "Path": "Organism|Kidney|Intracellular|MATE1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OAT3|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OCT1|Relative expression",
          "Value": 0.031737522
        },
        {
          "Path": "Organism|LargeIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0315629708
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Lung|Intracellular|OCT1|Relative expression",
          "Value": 0.0146483426
        },
        {
          "Path": "Organism|Muscle|Intracellular|OCT1|Relative expression",
          "Value": 0.0407525944
        },
        {
          "Path": "Organism|Pancreas|Intracellular|OCT1|Relative expression",
          "Value": 0.0065687827703
        },
        {
          "Path": "Organism|Skin|Intracellular|OCT1|Relative expression",
          "Value": 0.0119814482
        },
        {
          "Path": "Organism|SmallIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|Duodenum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|Spleen|Intracellular|OCT1|Relative expression",
          "Value": 0.0050234148247
        },
        {
          "Path": "Organism|Stomach|Intracellular|OCT1|Relative expression",
          "Value": 0.0093257582694
        }
      ],
      "Molecules": [
        {
          "Name": "OCT1",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "OAT3",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "MATE1",
          "Type": "Transporter",
          "TransportType": "Efflux",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainInterstitialToPlasma",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainTissueToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "EffluxBloodCellsToPlasma"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "EffluxInterstitialToPlasma"
            }
          ]
        }
      ]
    },
    {
      "Name": "Larsson_1982",
      "Seed": 722095890,
      "OriginData": {
        "CalculationMethods": [
          "SurfaceAreaPlsInt_VAR1",
          "Body surface area - Mosteller"
        ],
        "Species": "Human",
        "Population": "European_ICRP_2002",
        "Gender": "MALE",
        "Age": {
          "Value": 52.0,
          "Unit": "year(s)"
        }
      },
      "Parameters": [
        {
          "Path": "MATE1|Reference concentration",
          "Value": 0.13257,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "MATE1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "MATE1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|Reference concentration",
          "Value": 0.0917,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OAT3|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|Reference concentration",
          "Value": 0.16465,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OCT1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "Organism|Bone|Intracellular|OCT1|Relative expression",
          "Value": 0.02439093
        },
        {
          "Path": "Organism|Brain|Intracellular|OAT3|Relative expression",
          "Value": 0.00061613691932
        },
        {
          "Path": "Organism|Brain|Intracellular|OCT1|Relative expression",
          "Value": 0.0135293069
        },
        {
          "Path": "Organism|Gonads|Intracellular|OCT1|Relative expression",
          "Value": 0.0035130263768
        },
        {
          "Path": "Organism|Heart|Intracellular|OCT1|Relative expression",
          "Value": 0.0067231912312
        },
        {
          "Path": "Organism|Kidney|Intracellular|MATE1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OAT3|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OCT1|Relative expression",
          "Value": 0.031737522
        },
        {
          "Path": "Organism|LargeIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0315629708
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Lung|Intracellular|OCT1|Relative expression",
          "Value": 0.0146483426
        },
        {
          "Path": "Organism|Muscle|Intracellular|OCT1|Relative expression",
          "Value": 0.0407525944
        },
        {
          "Path": "Organism|Pancreas|Intracellular|OCT1|Relative expression",
          "Value": 0.0065687827703
        },
        {
          "Path": "Organism|Skin|Intracellular|OCT1|Relative expression",
          "Value": 0.0119814482
        },
        {
          "Path": "Organism|SmallIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|Duodenum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|Spleen|Intracellular|OCT1|Relative expression",
          "Value": 0.0050234148247
        },
        {
          "Path": "Organism|Stomach|Intracellular|OCT1|Relative expression",
          "Value": 0.0093257582694
        }
      ],
      "Molecules": [
        {
          "Name": "OCT1",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "OAT3",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "MATE1",
          "Type": "Transporter",
          "TransportType": "Efflux",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainInterstitialToPlasma",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainTissueToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "EffluxBloodCellsToPlasma"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "EffluxInterstitialToPlasma"
            }
          ]
        }
      ]
    },
    {
      "Name": "Lebert_1981",
      "Seed": 722143046,
      "OriginData": {
        "CalculationMethods": [
          "SurfaceAreaPlsInt_VAR1",
          "Body surface area - Mosteller"
        ],
        "Species": "Human",
        "Population": "European_ICRP_2002",
        "Gender": "MALE",
        "Age": {
          "Value": 28.0,
          "Unit": "year(s)"
        }
      },
      "Parameters": [
        {
          "Path": "MATE1|Reference concentration",
          "Value": 0.13257,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "MATE1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "MATE1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|Reference concentration",
          "Value": 0.0917,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OAT3|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|Reference concentration",
          "Value": 0.16465,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OCT1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "Organism|Bone|Intracellular|OCT1|Relative expression",
          "Value": 0.02439093
        },
        {
          "Path": "Organism|Brain|Intracellular|OAT3|Relative expression",
          "Value": 0.00061613691932
        },
        {
          "Path": "Organism|Brain|Intracellular|OCT1|Relative expression",
          "Value": 0.0135293069
        },
        {
          "Path": "Organism|Gonads|Intracellular|OCT1|Relative expression",
          "Value": 0.0035130263768
        },
        {
          "Path": "Organism|Heart|Intracellular|OCT1|Relative expression",
          "Value": 0.0067231912312
        },
        {
          "Path": "Organism|Kidney|Intracellular|MATE1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OAT3|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OCT1|Relative expression",
          "Value": 0.031737522
        },
        {
          "Path": "Organism|LargeIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0315629708
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Lung|Intracellular|OCT1|Relative expression",
          "Value": 0.0146483426
        },
        {
          "Path": "Organism|Muscle|Intracellular|OCT1|Relative expression",
          "Value": 0.0407525944
        },
        {
          "Path": "Organism|Pancreas|Intracellular|OCT1|Relative expression",
          "Value": 0.0065687827703
        },
        {
          "Path": "Organism|Skin|Intracellular|OCT1|Relative expression",
          "Value": 0.0119814482
        },
        {
          "Path": "Organism|SmallIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|Duodenum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|Spleen|Intracellular|OCT1|Relative expression",
          "Value": 0.0050234148247
        },
        {
          "Path": "Organism|Stomach|Intracellular|OCT1|Relative expression",
          "Value": 0.0093257582694
        }
      ],
      "Molecules": [
        {
          "Name": "OCT1",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "OAT3",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "MATE1",
          "Type": "Transporter",
          "TransportType": "Efflux",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainInterstitialToPlasma",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainTissueToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "EffluxBloodCellsToPlasma"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "EffluxInterstitialToPlasma"
            }
          ]
        }
      ]
    },
    {
      "Name": "Mihaly_1984",
      "Seed": 722194015,
      "OriginData": {
        "CalculationMethods": [
          "SurfaceAreaPlsInt_VAR1",
          "Body surface area - Mosteller"
        ],
        "Species": "Human",
        "Population": "European_ICRP_2002",
        "Gender": "MALE",
        "Age": {
          "Value": 37.0,
          "Unit": "year(s)"
        }
      },
      "Parameters": [
        {
          "Path": "MATE1|Reference concentration",
          "Value": 0.13257,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "MATE1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "MATE1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|Reference concentration",
          "Value": 0.0917,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OAT3|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|Reference concentration",
          "Value": 0.16465,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OCT1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "Organism|Bone|Intracellular|OCT1|Relative expression",
          "Value": 0.02439093
        },
        {
          "Path": "Organism|Brain|Intracellular|OAT3|Relative expression",
          "Value": 0.00061613691932
        },
        {
          "Path": "Organism|Brain|Intracellular|OCT1|Relative expression",
          "Value": 0.0135293069
        },
        {
          "Path": "Organism|Gonads|Intracellular|OCT1|Relative expression",
          "Value": 0.0035130263768
        },
        {
          "Path": "Organism|Heart|Intracellular|OCT1|Relative expression",
          "Value": 0.0067231912312
        },
        {
          "Path": "Organism|Kidney|Intracellular|MATE1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OAT3|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OCT1|Relative expression",
          "Value": 0.031737522
        },
        {
          "Path": "Organism|LargeIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0315629708
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Lung|Intracellular|OCT1|Relative expression",
          "Value": 0.0146483426
        },
        {
          "Path": "Organism|Muscle|Intracellular|OCT1|Relative expression",
          "Value": 0.0407525944
        },
        {
          "Path": "Organism|Pancreas|Intracellular|OCT1|Relative expression",
          "Value": 0.0065687827703
        },
        {
          "Path": "Organism|Skin|Intracellular|OCT1|Relative expression",
          "Value": 0.0119814482
        },
        {
          "Path": "Organism|SmallIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|Duodenum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|Spleen|Intracellular|OCT1|Relative expression",
          "Value": 0.0050234148247
        },
        {
          "Path": "Organism|Stomach|Intracellular|OCT1|Relative expression",
          "Value": 0.0093257582694
        }
      ],
      "Molecules": [
        {
          "Name": "OCT1",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "OAT3",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "MATE1",
          "Type": "Transporter",
          "TransportType": "Efflux",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainInterstitialToPlasma",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainTissueToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "EffluxBloodCellsToPlasma"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "EffluxInterstitialToPlasma"
            }
          ]
        }
      ]
    },
    {
      "Name": "Morgan_1983",
      "Seed": 722306359,
      "OriginData": {
        "CalculationMethods": [
          "SurfaceAreaPlsInt_VAR1",
          "Body surface area - Mosteller"
        ],
        "Species": "Human",
        "Population": "European_ICRP_2002",
        "Gender": "MALE",
        "Age": {
          "Value": 37.0,
          "Unit": "year(s)"
        }
      },
      "Parameters": [
        {
          "Path": "MATE1|Reference concentration",
          "Value": 0.13257,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "MATE1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "MATE1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|Reference concentration",
          "Value": 0.0917,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OAT3|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|Reference concentration",
          "Value": 0.16465,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OCT1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "Organism|Bone|Intracellular|OCT1|Relative expression",
          "Value": 0.02439093
        },
        {
          "Path": "Organism|Brain|Intracellular|OAT3|Relative expression",
          "Value": 0.00061613691932
        },
        {
          "Path": "Organism|Brain|Intracellular|OCT1|Relative expression",
          "Value": 0.0135293069
        },
        {
          "Path": "Organism|Gonads|Intracellular|OCT1|Relative expression",
          "Value": 0.0035130263768
        },
        {
          "Path": "Organism|Heart|Intracellular|OCT1|Relative expression",
          "Value": 0.0067231912312
        },
        {
          "Path": "Organism|Kidney|Intracellular|MATE1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OAT3|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OCT1|Relative expression",
          "Value": 0.031737522
        },
        {
          "Path": "Organism|LargeIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0315629708
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Lung|Intracellular|OCT1|Relative expression",
          "Value": 0.0146483426
        },
        {
          "Path": "Organism|Muscle|Intracellular|OCT1|Relative expression",
          "Value": 0.0407525944
        },
        {
          "Path": "Organism|Pancreas|Intracellular|OCT1|Relative expression",
          "Value": 0.0065687827703
        },
        {
          "Path": "Organism|Skin|Intracellular|OCT1|Relative expression",
          "Value": 0.0119814482
        },
        {
          "Path": "Organism|SmallIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|Duodenum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|Spleen|Intracellular|OCT1|Relative expression",
          "Value": 0.0050234148247
        },
        {
          "Path": "Organism|Stomach|Intracellular|OCT1|Relative expression",
          "Value": 0.0093257582694
        }
      ],
      "Molecules": [
        {
          "Name": "OCT1",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "OAT3",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "MATE1",
          "Type": "Transporter",
          "TransportType": "Efflux",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainInterstitialToPlasma",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainTissueToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "EffluxBloodCellsToPlasma"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "EffluxInterstitialToPlasma"
            }
          ]
        }
      ]
    },
    {
      "Name": "Somogyi_1981",
      "Seed": 722357781,
      "OriginData": {
        "CalculationMethods": [
          "SurfaceAreaPlsInt_VAR1",
          "Body surface area - Mosteller"
        ],
        "Species": "Human",
        "Population": "European_ICRP_2002",
        "Gender": "MALE",
        "Age": {
          "Value": 25.0,
          "Unit": "year(s)"
        },
        "Weight": {
          "Value": 65.0,
          "Unit": "kg"
        }
      },
      "Parameters": [
        {
          "Path": "MATE1|Reference concentration",
          "Value": 0.13257,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "MATE1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "MATE1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|Reference concentration",
          "Value": 0.0917,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OAT3|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|Reference concentration",
          "Value": 0.16465,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OCT1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "Organism|Bone|Intracellular|OCT1|Relative expression",
          "Value": 0.02439093
        },
        {
          "Path": "Organism|Brain|Intracellular|OAT3|Relative expression",
          "Value": 0.00061613691932
        },
        {
          "Path": "Organism|Brain|Intracellular|OCT1|Relative expression",
          "Value": 0.0135293069
        },
        {
          "Path": "Organism|Gonads|Intracellular|OCT1|Relative expression",
          "Value": 0.0035130263768
        },
        {
          "Path": "Organism|Heart|Intracellular|OCT1|Relative expression",
          "Value": 0.0067231912312
        },
        {
          "Path": "Organism|Kidney|Intracellular|MATE1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OAT3|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OCT1|Relative expression",
          "Value": 0.031737522
        },
        {
          "Path": "Organism|LargeIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0315629708
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Lung|Intracellular|OCT1|Relative expression",
          "Value": 0.0146483426
        },
        {
          "Path": "Organism|Muscle|Intracellular|OCT1|Relative expression",
          "Value": 0.0407525944
        },
        {
          "Path": "Organism|Pancreas|Intracellular|OCT1|Relative expression",
          "Value": 0.0065687827703
        },
        {
          "Path": "Organism|Skin|Intracellular|OCT1|Relative expression",
          "Value": 0.0119814482
        },
        {
          "Path": "Organism|SmallIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|Duodenum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|Spleen|Intracellular|OCT1|Relative expression",
          "Value": 0.0050234148247
        },
        {
          "Path": "Organism|Stomach|Intracellular|OCT1|Relative expression",
          "Value": 0.0093257582694
        }
      ],
      "Molecules": [
        {
          "Name": "OCT1",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "OAT3",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "MATE1",
          "Type": "Transporter",
          "TransportType": "Efflux",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainInterstitialToPlasma",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainTissueToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "EffluxBloodCellsToPlasma"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "EffluxInterstitialToPlasma"
            }
          ]
        }
      ]
    },
    {
      "Name": "Walkenstein_1978",
      "Seed": 722408750,
      "OriginData": {
        "CalculationMethods": [
          "SurfaceAreaPlsInt_VAR1",
          "Body surface area - Mosteller"
        ],
        "Species": "Human",
        "Population": "WhiteAmerican_NHANES_1997",
        "Gender": "MALE",
        "Age": {
          "Value": 30.0,
          "Unit": "year(s)"
        }
      },
      "Parameters": [
        {
          "Path": "MATE1|Reference concentration",
          "Value": 0.13257,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "MATE1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "MATE1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|Reference concentration",
          "Value": 0.0917,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OAT3|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OAT3|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|Reference concentration",
          "Value": 0.16465,
          "Unit": "µmol/l",
          "ValueOrigin": {
            "Source": "Unknown"
          }
        },
        {
          "Path": "OCT1|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "OCT1|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        },
        {
          "Path": "Organism|Bone|Intracellular|OCT1|Relative expression",
          "Value": 0.02439093
        },
        {
          "Path": "Organism|Brain|Intracellular|OAT3|Relative expression",
          "Value": 0.00061613691932
        },
        {
          "Path": "Organism|Brain|Intracellular|OCT1|Relative expression",
          "Value": 0.0135293069
        },
        {
          "Path": "Organism|Gonads|Intracellular|OCT1|Relative expression",
          "Value": 0.0035130263768
        },
        {
          "Path": "Organism|Heart|Intracellular|OCT1|Relative expression",
          "Value": 0.0067231912312
        },
        {
          "Path": "Organism|Kidney|Intracellular|MATE1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OAT3|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Kidney|Intracellular|OCT1|Relative expression",
          "Value": 0.031737522
        },
        {
          "Path": "Organism|LargeIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0315629708
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Pericentral|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OAT3|Relative expression",
          "Value": 0.00016503667482
        },
        {
          "Path": "Organism|Liver|Periportal|Intracellular|OCT1|Relative expression",
          "Value": 1.0
        },
        {
          "Path": "Organism|Lung|Intracellular|OCT1|Relative expression",
          "Value": 0.0146483426
        },
        {
          "Path": "Organism|Muscle|Intracellular|OCT1|Relative expression",
          "Value": 0.0407525944
        },
        {
          "Path": "Organism|Pancreas|Intracellular|OCT1|Relative expression",
          "Value": 0.0065687827703
        },
        {
          "Path": "Organism|Skin|Intracellular|OCT1|Relative expression",
          "Value": 0.0119814482
        },
        {
          "Path": "Organism|SmallIntestine|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|Duodenum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|LowerJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperIleum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|SmallIntestine|Mucosa|UpperJejunum|Intracellular|OCT1|Relative expression",
          "Value": 0.0245459351
        },
        {
          "Path": "Organism|Spleen|Intracellular|OCT1|Relative expression",
          "Value": 0.0050234148247
        },
        {
          "Path": "Organism|Stomach|Intracellular|OCT1|Relative expression",
          "Value": 0.0093257582694
        }
      ],
      "Molecules": [
        {
          "Name": "OCT1",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "OAT3",
          "Type": "Transporter",
          "TransportType": "Influx",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainPlasmaToInterstitial",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "InfluxBrainInterstitialToTissue",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "InfluxLumenToMucosaIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "InfluxInterstitialToIntracellular",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "InfluxPlasmaToBloodCells"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "InfluxPlasmaToInterstitial"
            }
          ]
        },
        {
          "Name": "MATE1",
          "Type": "Transporter",
          "TransportType": "Efflux",
          "Expression": [
            {
              "Name": "Bone",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainInterstitialToPlasma",
              "CompartmentName": "Plasma"
            },
            {
              "Name": "Brain",
              "TransportDirection": "EffluxBrainTissueToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Fat",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Gonads",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Heart",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Kidney",
              "TransportDirection": "ExcretionKidney",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Stomach",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "SmallIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Duodenum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerJejunum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "UpperIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "LowerIleum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "LargeIntestine",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Caecum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonAscendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonTransversum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonDescendens",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "ColonSigmoid",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Rectum",
              "TransportDirection": "EffluxMucosaIntracellularToLumen",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Periportal",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Interstitial"
            },
            {
              "Name": "Pericentral",
              "TransportDirection": "ExcretionLiver",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Lung",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Muscle",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Pancreas",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Skin",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "Spleen",
              "TransportDirection": "EffluxIntracellularToInterstitial",
              "CompartmentName": "Intracellular"
            },
            {
              "Name": "BloodCells",
              "TransportDirection": "EffluxBloodCellsToPlasma"
            },
            {
              "Name": "VascularEndothelium",
              "TransportDirection": "EffluxInterstitialToPlasma"
            }
          ]
        }
      ]
    }
  ],
  "Compounds": [
    {
      "Name": "Cimetidine",
      "IsSmallMolecule": true,
      "Lipophilicity": [
        {
          "Name": "Measurement",
          "Parameters": [
            {
              "Name": "Lipophilicity",
              "Value": 1.655,
              "Unit": "Log Units",
              "ValueOrigin": {
                "Source": "ParameterIdentification"
              }
            }
          ]
        }
      ],
      "FractionUnbound": [
        {
          "Name": "Measurement",
          "Species": "Human",
          "Parameters": [
            {
              "Name": "Fraction unbound (plasma, reference value)",
              "Value": 0.78,
              "ValueOrigin": {
                "Source": "Publication",
                "Description": "Taylor 1978"
              }
            }
          ]
        }
      ],
      "Solubility": [
        {
          "Name": "Measurement",
          "Parameters": [
            {
              "Name": "Solubility at reference pH",
              "Value": 24.0,
              "Unit": "mg/ml",
              "ValueOrigin": {
                "Source": "Publication",
                "Description": "Avdeef 2001"
              }
            },
            {
              "Name": "Reference pH",
              "Value": 6.8,
              "ValueOrigin": {
                "Source": "Publication",
                "Description": "Avdeef 2001"
              }
            }
          ]
        }
      ],
      "IntestinalPermeability": [
        {
          "Name": "Fit",
          "Parameters": [
            {
              "Name": "Specific intestinal permeability (transcellular)",
              "Value": 5.2554004942E-06,
              "Unit": "cm/min",
              "ValueOrigin": {
                "Source": "ParameterIdentification",
                "Method": "ParameterIdentification",
                "Description": "Value updated from 'Parameter Identification' on 2021-09-13 17:00"
              }
            }
          ]
        }
      ],
      "PkaTypes": [
        {
          "Type": "Base",
          "Pka": 6.93,
          "ValueOrigin": {
            "Source": "Publication",
            "Description": "Avdeef 2001"
          }
        },
        {
          "Type": "Acid",
          "Pka": 13.38,
          "ValueOrigin": {
            "Source": "Publication",
            "Description": "Avdeef 2001"
          }
        }
      ],
      "Processes": [
        {
          "InternalName": "LiverClearance",
          "DataSource": "Somogyi 1983",
          "Species": "Human",
          "Parameters": [
            {
              "Name": "Fraction unbound (experiment)",
              "Value": 0.78
            },
            {
              "Name": "Lipophilicity (experiment)",
              "Value": 1.655,
              "Unit": "Log Units"
            },
            {
              "Name": "Plasma clearance",
              "Value": 0.0,
              "Unit": "ml/min/kg"
            },
            {
              "Name": "Specific clearance",
              "Value": 0.1209722937,
              "Unit": "1/min",
              "ValueOrigin": {
                "Source": "ParameterIdentification",
                "Method": "ParameterIdentification",
                "Description": "Value updated from 'Parameter Identification' on 2021-09-13 17:00"
              }
            }
          ]
        },
        {
          "InternalName": "ActiveTransportSpecific_MM",
          "DataSource": "Paper",
          "Molecule": "MATE1",
          "Parameters": [
            {
              "Name": "Transporter concentration",
              "Value": 1.0,
              "Unit": "µmol/l"
            },
            {
              "Name": "Vmax",
              "Value": 0.0,
              "Unit": "µmol/l/min"
            },
            {
              "Name": "Km",
              "Value": 8.0,
              "Unit": "µmol/l",
              "ValueOrigin": {
                "Source": "ParameterIdentification"
              }
            },
            {
              "Name": "kcat",
              "Value": 159.4749627996,
              "Unit": "1/min",
              "ValueOrigin": {
                "Source": "ParameterIdentification",
                "Method": "ParameterIdentification",
                "Description": "Value updated from 'Parameter Identification' on 2021-09-13 17:00"
              }
            }
          ]
        },
        {
          "InternalName": "ActiveTransportSpecific_MM",
          "DataSource": "Paper",
          "Molecule": "OAT3",
          "Parameters": [
            {
              "Name": "Transporter concentration",
              "Value": 1.0,
              "Unit": "µmol/l"
            },
            {
              "Name": "Vmax",
              "Value": 0.0,
              "Unit": "µmol/l/min"
            },
            {
              "Name": "Km",
              "Value": 149.0,
              "Unit": "µmol/l",
              "ValueOrigin": {
                "Source": "Publication",
                "Description": "Tahara 2005"
              }
            },
            {
              "Name": "kcat",
              "Value": 2522831.1016,
              "Unit": "1/min",
              "ValueOrigin": {
                "Source": "ParameterIdentification",
                "Method": "ParameterIdentification",
                "Description": "Value updated from 'Parameter Identification' on 2021-09-13 17:00"
              }
            }
          ]
        },
        {
          "InternalName": "ActiveTransportSpecific_MM",
          "DataSource": "Paper",
          "Molecule": "OCT1",
          "Parameters": [
            {
              "Name": "Transporter concentration",
              "Value": 1.0,
              "Unit": "µmol/l"
            },
            {
              "Name": "Vmax",
              "Value": 0.0,
              "Unit": "µmol/l/min"
            },
            {
              "Name": "Km",
              "Value": 2600.0,
              "Unit": "µmol/l",
              "ValueOrigin": {
                "Source": "Publication",
                "Description": "Umehara 2007"
              }
            },
            {
              "Name": "kcat",
              "Value": 14098.3224931732,
              "Unit": "1/min",
              "ValueOrigin": {
                "Source": "ParameterIdentification",
                "Method": "ParameterIdentification",
                "Description": "Value updated from 'Parameter Identification' on 2021-09-13 17:00"
              }
            }
          ]
        },
        {
          "InternalName": "GlomerularFiltration",
          "DataSource": "GFR",
          "Species": "Human",
          "Parameters": [
            {
              "Name": "GFR fraction",
              "Value": 1.0
            }
          ]
        },
        {
          "InternalName": "CompetitiveInhibition",
          "DataSource": "Ito 2012",
          "Molecule": "OCT1",
          "Parameters": [
            {
              "Name": "Ki",
              "Value": 104.0,
              "Unit": "µmol/l",
              "ValueOrigin": {
                "Source": "Publication",
                "Description": "Ito 2012"
              }
            }
          ]
        },
        {
          "InternalName": "CompetitiveInhibition",
          "DataSource": "Ito 2012",
          "Molecule": "OCT2",
          "Parameters": [
            {
              "Name": "Ki",
              "Value": 124.0,
              "Unit": "µmol/l",
              "ValueOrigin": {
                "Source": "Publication",
                "Description": "Ito 2012"
              }
            }
          ]
        },
        {
          "InternalName": "CompetitiveInhibition",
          "DataSource": "Ito 2012",
          "Molecule": "MATE1",
          "Parameters": [
            {
              "Name": "Ki",
              "Value": 3.8,
              "Unit": "µmol/l",
              "ValueOrigin": {
                "Source": "Other",
                "Description": "NBI measurement"
              }
            }
          ]
        },
        {
          "InternalName": "CompetitiveInhibition",
          "DataSource": "Wrighton 1994",
          "Molecule": "CYP3A4",
          "Parameters": [
            {
              "Name": "Ki",
              "Value": 268.0,
              "Unit": "µmol/l"
            }
          ]
        }
      ],
      "CalculationMethods": [
        "Cellular partition coefficient method - Rodgers and Rowland",
        "Cellular permeability - PK-Sim Standard"
      ],
      "Parameters": [
        {
          "Name": "Molecular weight",
          "Value": 252.34,
          "Unit": "g/mol",
          "ValueOrigin": {
            "Source": "Database",
            "Description": "Drugbank"
          }
        }
      ]
    }
  ],
  "Formulations": [
    {
      "Name": "Tablet",
      "FormulationType": "Formulation_Tablet_Weibull",
      "Parameters": [
        {
          "Name": "Dissolution time (50% dissolved)",
          "Value": 1.0,
          "Unit": "min"
        },
        {
          "Name": "Lag time",
          "Value": 0.0,
          "Unit": "h"
        },
        {
          "Name": "Dissolution shape",
          "Value": 10.0
        },
        {
          "Name": "Use as suspension",
          "Value": 1.0
        }
      ]
    }
  ],
  "Protocols": [
    {
      "Name": "iv 100 mg (5 min)",
      "ApplicationType": "Intravenous",
      "DosingInterval": "Single",
      "Parameters": [
        {
          "Name": "Start time",
          "Value": 0.0,
          "Unit": "h"
        },
        {
          "Name": "InputDose",
          "Value": 100.0,
          "Unit": "mg"
        },
        {
          "Name": "Infusion time",
          "Value": 5.0,
          "Unit": "min"
        }
      ]
    },
    {
      "Name": "iv 200 mg (30 min)",
      "ApplicationType": "Intravenous",
      "DosingInterval": "Single",
      "Parameters": [
        {
          "Name": "Start time",
          "Value": 0.0,
          "Unit": "h"
        },
        {
          "Name": "InputDose",
          "Value": 200.0,
          "Unit": "mg"
        },
        {
          "Name": "Infusion time",
          "Value": 30.0,
          "Unit": "min"
        }
      ]
    },
    {
      "Name": "iv 200 mg (5 min)",
      "ApplicationType": "Intravenous",
      "DosingInterval": "Single",
      "Parameters": [
        {
          "Name": "Start time",
          "Value": 0.0,
          "Unit": "h"
        },
        {
          "Name": "InputDose",
          "Value": 200.0,
          "Unit": "mg"
        },
        {
          "Name": "Infusion time",
          "Value": 5.0,
          "Unit": "min"
        }
      ]
    },
    {
      "Name": "iv 200 mg (bol)",
      "ApplicationType": "IntravenousBolus",
      "DosingInterval": "Single",
      "Parameters": [
        {
          "Name": "Start time",
          "Value": 0.0,
          "Unit": "h"
        },
        {
          "Name": "InputDose",
          "Value": 200.0,
          "Unit": "mg"
        }
      ]
    },
    {
      "Name": "iv 300 mg (2 min)",
      "ApplicationType": "Intravenous",
      "DosingInterval": "Single",
      "Parameters": [
        {
          "Name": "Start time",
          "Value": 0.0,
          "Unit": "h"
        },
        {
          "Name": "InputDose",
          "Value": 300.0,
          "Unit": "mg"
        },
        {
          "Name": "Infusion time",
          "Value": 2.0,
          "Unit": "min"
        }
      ]
    },
    {
      "Name": "Split dose - 200 mg Bodemar 1979.2",
      "ApplicationType": "Oral",
      "DosingInterval": "Single",
      "Parameters": [
        {
          "Name": "Start time",
          "Value": 0.0,
          "Unit": "h"
        },
        {
          "Name": "InputDose",
          "Value": 200.0,
          "Unit": "mg"
        },
        {
          "Name": "Volume of water/body weight",
          "Value": 3.5,
          "Unit": "ml/kg"
        }
      ]
    },
    {
      "Name": "Split dose - 300 mg qid Barbhaiya 1995",
      "DosingInterval": "Single",
      "Schemas": [
        {
          "Name": "Schema 1",
          "SchemaItems": [
            {
              "Name": "Schema Item 2",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 7.7,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 111.0,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            },
            {
              "Name": "Schema Item 4",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 6.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 189.0,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            },
            {
              "Name": "Schema Item 5",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 12.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 189.0,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            },
            {
              "Name": "Schema Item 6",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 13.7,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 111.0,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            },
            {
              "Name": "Schema Item 7",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 16.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 189.0,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            },
            {
              "Name": "Schema Item 8",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 17.7,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 111.0,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            }
          ],
          "Parameters": [
            {
              "Name": "Start time",
              "Value": 0.0,
              "Unit": "h"
            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 6.0,
              "ValueOrigin": {
                "Source": "Unknown"
              }
            },
            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        },
        {
          "Name": "Schema 2",
          "SchemaItems": [
            {
              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 189.0,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            },
            {
              "Name": "Schema Item 2",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 1.7,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 111.0,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            }
          ],
          "Parameters": [
            {
              "Name": "Start time",
              "Value": 0.0,
              "Unit": "h"
            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 7.0,
              "ValueOrigin": {
                "Source": "Unknown"
              }
            },
            {
              "Name": "TimeBetweenRepetitions",
              "Value": 24.0,
              "Unit": "h",
              "ValueOrigin": {
                "Source": "Unknown"
              }
            }
          ]
        }
      ],
      "TimeUnit": "h"
    },
    {
      "Name": "Split dose - 200 mg tid + 400 mg Bodemar 1981",
      "DosingInterval": "Single",
      "Schemas": [
        {
          "Name": "Schema 1",
          "SchemaItems": [
            {
              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 126.0,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            },
            {
              "Name": "Schema Item 2",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 4.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 126.0,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            },
            {
              "Name": "Schema Item 3",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 9.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 126.0,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            },
            {
              "Name": "Schema Item 4",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 1.7,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 74.0,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            },
            {
              "Name": "Schema Item 5",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 5.7,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 74.0,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            },
            {
              "Name": "Schema Item 6",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 10.7,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 74.0,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            },
            {
              "Name": "Schema Item 7",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 14.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 252.0,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            },
            {
              "Name": "Schema Item 8",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 15.7,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 148.0,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            }
          ],
          "Parameters": [
            {
              "Name": "Start time",
              "Value": 0.0,
              "Unit": "h"
            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 8.0,
              "ValueOrigin": {
                "Source": "Unknown"
              }
            },
            {
              "Name": "TimeBetweenRepetitions",
              "Value": 24.0,
              "Unit": "h",
              "ValueOrigin": {
                "Source": "Unknown"
              }
            }
          ]
        }
      ],
      "TimeUnit": "h"
    },
    {
      "Name": "Split dose - 200 mg Bodemar 1979.1",
      "DosingInterval": "Single",
      "Schemas": [
        {
          "Name": "Schema 1",
          "SchemaItems": [
            {
              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 120.0,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            }
          ],
          "Parameters": [
            {
              "Name": "Start time",
              "Value": 0.0,
              "Unit": "h"
            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
            },
            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        },
        {
          "Name": "Schema 2",
          "SchemaItems": [
            {
              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 80.0,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            }
          ],
          "Parameters": [
            {
              "Name": "Start time",
              "Value": 1.94,
              "Unit": "h",
              "ValueOrigin": {
                "Source": "Unknown"
              }
            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
            },
            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        }
      ],
      "TimeUnit": "h"
    },
    {
      "Name": "Split dose - 200 mg Bodemar 1979.3",
      "DosingInterval": "Single",
      "Schemas": [
        {
          "Name": "Schema 1",
          "SchemaItems": [
            {
              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 138.35,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            }
          ],
          "Parameters": [
            {
              "Name": "Start time",
              "Value": 0.0,
              "Unit": "h"
            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
            },
            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        },
        {
          "Name": "Schema 2",
          "SchemaItems": [
            {
              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 61.65,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            }
          ],
          "Parameters": [
            {
              "Name": "Start time",
              "Value": 1.97,
              "Unit": "h",
              "ValueOrigin": {
                "Source": "Unknown"
              }
            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
            },
            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        }
      ],
      "TimeUnit": "h"
    },
    {
      "Name": "Split dose - 200 mg Bodemar 1981.1",
      "DosingInterval": "Single",
      "Schemas": [
        {
          "Name": "Schema 1",
          "SchemaItems": [
            {
              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 114.88,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            }
          ],
          "Parameters": [
            {
              "Name": "Start time",
              "Value": 0.0,
              "Unit": "h"
            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
            },
            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        },
        {
          "Name": "Schema 2",
          "SchemaItems": [
            {
              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 85.12,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            }
          ],
          "Parameters": [
            {
              "Name": "Start time",
              "Value": 1.68,
              "Unit": "h",
              "ValueOrigin": {
                "Source": "Unknown"
              }
            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
            },
            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        }
      ],
      "TimeUnit": "h"
    },
    {
      "Name": "Split dose - 200 mg Burland 1975 caps",
      "DosingInterval": "Single",
      "Schemas": [
        {
          "Name": "Schema 1",
          "SchemaItems": [
            {
              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 184.46,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            }
          ],
          "Parameters": [
            {
              "Name": "Start time",
              "Value": 0.0,
              "Unit": "h"
            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
            },
            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        },
        {
          "Name": "Schema 2",
          "SchemaItems": [
            {
              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 15.54,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            }
          ],
          "Parameters": [
            {
              "Name": "Start time",
              "Value": 1.32,
              "Unit": "h",
              "ValueOrigin": {
                "Source": "Unknown"
              }
            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
            },
            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        }
      ],
      "TimeUnit": "h"
    },
    {
      "Name": "Split dose - 200 mg Burland 1975 sol",
      "DosingInterval": "Single",
      "Schemas": [
        {
          "Name": "Schema 1",
          "SchemaItems": [
            {
              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 170.54,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
            }
          ],
          "Parameters": [
            {
              "Name": "Start time",
              "Value": 0.0,
              "Unit": "h"
            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
            },
            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        },
        {
          "Name": "Schema 2",
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            {
              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 29.46,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
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          ],
          "Parameters": [
            {
              "Name": "Start time",
              "Value": 1.97,
              "Unit": "h",
              "ValueOrigin": {
                "Source": "Unknown"
              }
            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
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            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        }
      ],
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    },
    {
      "Name": "Split dose - 200 mg Kanto 1981",
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        {
          "Name": "Schema 1",
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            {
              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 144.72,
                  "Unit": "mg"
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                {
                  "Name": "Volume of water/body weight",
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                  "Unit": "ml/kg"
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              ]
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          ],
          "Parameters": [
            {
              "Name": "Start time",
              "Value": 0.0,
              "Unit": "h"
            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
            },
            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        },
        {
          "Name": "Schema 2",
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            {
              "Name": "Schema Item 1",
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              "FormulationKey": "Formulation",
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                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 55.28,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
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          ],
          "Parameters": [
            {
              "Name": "Start time",
              "Value": 2.46,
              "Unit": "h",
              "ValueOrigin": {
                "Source": "Unknown"
              }
            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
            },
            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        }
      ],
      "TimeUnit": "h"
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    {
      "Name": "Split dose - 200 mg Mihaly 1984",
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        {
          "Name": "Schema 1",
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            {
              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
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                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 100.84,
                  "Unit": "mg"
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                {
                  "Name": "Volume of water/body weight",
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                  "Unit": "ml/kg"
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          ],
          "Parameters": [
            {
              "Name": "Start time",
              "Value": 0.0,
              "Unit": "h"
            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
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            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        },
        {
          "Name": "Schema 2",
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            {
              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
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                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 99.16,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
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              ]
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          ],
          "Parameters": [
            {
              "Name": "Start time",
              "Value": 1.39,
              "Unit": "h",
              "ValueOrigin": {
                "Source": "Unknown"
              }
            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
            },
            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        }
      ],
      "TimeUnit": "h"
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      "Name": "Split dose - 300 mg D'Angio1986",
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        {
          "Name": "Schema 1",
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            {
              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
              "Parameters": [
                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 230.03,
                  "Unit": "mg"
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                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
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              ]
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          ],
          "Parameters": [
            {
              "Name": "Start time",
              "Value": 0.0,
              "Unit": "h"
            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
            },
            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        },
        {
          "Name": "Schema 2",
          "SchemaItems": [
            {
              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
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                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
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                {
                  "Name": "InputDose",
                  "Value": 69.98,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
                  "Value": 3.5,
                  "Unit": "ml/kg"
                }
              ]
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          ],
          "Parameters": [
            {
              "Name": "Start time",
              "Value": 1.93,
              "Unit": "h",
              "ValueOrigin": {
                "Source": "Unknown"
              }
            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
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            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        }
      ],
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        {
          "Name": "Schema 1",
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            {
              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
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                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 255.6,
                  "Unit": "mg"
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                {
                  "Name": "Volume of water/body weight",
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                  "Unit": "ml/kg"
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          "Parameters": [
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              "Name": "Start time",
              "Value": 0.0,
              "Unit": "h"
            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
            },
            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
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          "Name": "Schema 2",
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              "Name": "Schema Item 1",
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              "FormulationKey": "Formulation",
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                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
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                {
                  "Name": "InputDose",
                  "Value": 44.4,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
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                  "Unit": "ml/kg"
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              ]
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          "Parameters": [
            {
              "Name": "Start time",
              "Value": 1.64,
              "Unit": "h",
              "ValueOrigin": {
                "Source": "Unknown"
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            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
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            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        }
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      "TimeUnit": "h"
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            {
              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
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                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 215.41,
                  "Unit": "mg"
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                {
                  "Name": "Volume of water/body weight",
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                  "Unit": "ml/kg"
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          "Parameters": [
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              "Name": "Start time",
              "Value": 0.0,
              "Unit": "h"
            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
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            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
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          "Name": "Schema 2",
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              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
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                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 84.59,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
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                  "Unit": "ml/kg"
                }
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          "Parameters": [
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              "Name": "Start time",
              "Value": 1.66,
              "Unit": "h",
              "ValueOrigin": {
                "Source": "Unknown"
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            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
            },
            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        }
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      "Name": "Split dose - 400 mg Bodemar 1979",
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            {
              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
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                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 254.49,
                  "Unit": "mg"
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                {
                  "Name": "Volume of water/body weight",
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                  "Unit": "ml/kg"
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          "Parameters": [
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              "Name": "Start time",
              "Value": 0.0,
              "Unit": "h"
            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
            },
            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        },
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          "Name": "Schema 2",
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            {
              "Name": "Schema Item 1",
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                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
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                {
                  "Name": "InputDose",
                  "Value": 145.51,
                  "Unit": "mg"
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                {
                  "Name": "Volume of water/body weight",
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                  "Unit": "ml/kg"
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          "Parameters": [
            {
              "Name": "Start time",
              "Value": 1.93,
              "Unit": "h",
              "ValueOrigin": {
                "Source": "Unknown"
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            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
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            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        }
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      "Name": "Split dose - 400 mg Bodemar 1981",
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              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
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                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
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                  "Unit": "mg"
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                {
                  "Name": "Volume of water/body weight",
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                  "Unit": "ml/kg"
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          "Parameters": [
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              "Name": "Start time",
              "Value": 0.0,
              "Unit": "h"
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            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
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            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
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          ]
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          "Name": "Schema 2",
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              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
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                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 192.22,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
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                  "Unit": "ml/kg"
                }
              ]
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          ],
          "Parameters": [
            {
              "Name": "Start time",
              "Value": 1.41,
              "Unit": "h",
              "ValueOrigin": {
                "Source": "Unknown"
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            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
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            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        }
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              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
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                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
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                  "Unit": "mg"
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                {
                  "Name": "Volume of water/body weight",
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                  "Unit": "ml/kg"
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              "Name": "Start time",
              "Value": 0.0,
              "Unit": "h"
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            {
              "Name": "NumberOfRepetitions",
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            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
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          ]
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          "Name": "Schema 2",
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              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
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                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 53.14,
                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
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                  "Unit": "ml/kg"
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              ]
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          "Parameters": [
            {
              "Name": "Start time",
              "Value": 1.53,
              "Unit": "h",
              "ValueOrigin": {
                "Source": "Unknown"
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            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
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            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        }
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              "Name": "Schema Item 1",
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              "FormulationKey": "Formulation",
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                  "Name": "Start time",
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                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
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                  "Unit": "mg"
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                {
                  "Name": "Volume of water/body weight",
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                  "Unit": "ml/kg"
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          "Parameters": [
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              "Name": "Start time",
              "Value": 0.0,
              "Unit": "h"
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            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
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            {
              "Name": "TimeBetweenRepetitions",
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              "Unit": "h"
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          ]
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          "Name": "Schema 2",
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              "Name": "Schema Item 1",
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              "FormulationKey": "Formulation",
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                {
                  "Name": "Start time",
                  "Value": 0.0,
                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
                  "Value": 148.0,
                  "Unit": "mg"
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                {
                  "Name": "Volume of water/body weight",
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          "Parameters": [
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              "Name": "Start time",
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              "ValueOrigin": {
                "Source": "Unknown"
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            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
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            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
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          ]
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      "Name": "Split dose - 800 mg Bodemar 1981",
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              "Name": "Schema Item 1",
              "ApplicationType": "Oral",
              "FormulationKey": "Formulation",
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                  "Name": "Start time",
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                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
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                  "Unit": "mg"
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                {
                  "Name": "Volume of water/body weight",
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                  "Unit": "ml/kg"
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              ]
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          "Parameters": [
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              "Name": "Start time",
              "Value": 0.0,
              "Unit": "h"
            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
            },
            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        },
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          "Name": "Schema 2",
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              "Name": "Schema Item 1",
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                {
                  "Name": "Start time",
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                  "Unit": "h"
                },
                {
                  "Name": "InputDose",
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                  "Unit": "mg"
                },
                {
                  "Name": "Volume of water/body weight",
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                  "Unit": "ml/kg"
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              ]
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          ],
          "Parameters": [
            {
              "Name": "Start time",
              "Value": 1.64,
              "Unit": "h",
              "ValueOrigin": {
                "Source": "Unknown"
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            },
            {
              "Name": "NumberOfRepetitions",
              "Value": 1.0
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            {
              "Name": "TimeBetweenRepetitions",
              "Value": 0.0,
              "Unit": "h"
            }
          ]
        }
      ],
      "TimeUnit": "h"
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      "Name": "Split dose - 800 mg qd Tiseo 1998",
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              "FormulationKey": "Formulation",
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                  "Name": "Start time",
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                  "Unit": "h"
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                {
                  "Name": "InputDose",
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                  "Unit": "mg"
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                {
                  "Name": "Volume of water/body weight",
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                  "Unit": "ml/kg"
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              ]
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            {
              "Name": "Schema Item 2",
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                  "Name": "Start time",
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                  "Unit": "h"
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                {
                  "Name": "InputDose",
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                  "Unit": "mg"
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                  "Name": "Volume of water/body weight",
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                  "Unit": "ml/kg"
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              ]
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              "Name": "Start time",
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              "Unit": "h"
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            {
              "Name": "NumberOfRepetitions",
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              "ValueOrigin": {
                "Source": "Unknown"
              }
            },
            {
              "Name": "TimeBetweenRepetitions",
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              "Unit": "h",
              "ValueOrigin": {
                "Source": "Unknown"
              }
            }
          ]
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      ]
    },
    {
      "Name": "po 800 mg (tab) qd, Tiseo 1998, n=18",
      "Model": "4Comp",
      "ObservedData": [
        "Tiseo 1998 - PO 800 mg QD - Cimetidine - PO - 800 mg - Plasma - agg. (n=19)"
      ],
      "Solver": {},
      "OutputSchema": [
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          "Parameters": [
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      "Parameters": [
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          "Value": 3.5,
          "Unit": "ml/kg"
        },
        {
          "Path": "Undefined Liver|Reference concentration",
          "Value": 1.0,
          "Unit": "µmol/l"
        },
        {
          "Path": "Undefined Liver|t1/2 (intestine)",
          "Value": 23.0,
          "Unit": "h"
        },
        {
          "Path": "Undefined Liver|t1/2 (liver)",
          "Value": 36.0,
          "Unit": "h"
        }
      ],
      "OutputSelections": [
        "Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)"
      ],
      "Individual": "Tiseo_1998",
      "Compounds": [
        {
          "Name": "Cimetidine",
          "CalculationMethods": [
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            "Cellular permeability - PK-Sim Standard"
          ],
          "Alternatives": [
            {
              "AlternativeName": "Fit",
              "GroupName": "COMPOUND_INTESTINAL_PERMEABILITY"
            }
          ],
          "Processes": [
            {
              "Name": "Total Hepatic Clearance-Somogyi 1983",
              "SystemicProcessType": "Hepatic"
            },
            {
              "Name": "OCT1-Paper",
              "MoleculeName": "OCT1"
            },
            {
              "Name": "OAT3-Paper",
              "MoleculeName": "OAT3"
            },
            {
              "Name": "MATE1-Paper",
              "MoleculeName": "MATE1"
            },
            {
              "Name": "Glomerular Filtration-GFR",
              "SystemicProcessType": "GFR"
            }
          ],
          "Protocol": {
            "Name": "Split dose - 800 mg qd Tiseo 1998",
            "Formulations": [
              {
                "Name": "Tablet",
                "Key": "Formulation"
              }
            ]
          }
        }
      ],
      "HasResults": true,
      "IndividualAnalyses": [
        {
          "Axes": [
            {
              "Unit": "h",
              "Dimension": "Time",
              "Type": "X",
              "GridLines": false,
              "Visible": true,
              "DefaultColor": "#FFFFFF",
              "DefaultLineStyle": "None",
              "Scaling": "Linear",
              "NumberMode": "Normal"
            },
            {
              "Unit": "µg/ml",
              "Dimension": "Concentration (molar)",
              "Type": "Y",
              "GridLines": false,
              "Visible": true,
              "DefaultColor": "#FFFFFF",
              "DefaultLineStyle": "Solid",
              "Scaling": "Log",
              "NumberMode": "Normal"
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          ],
          "Curves": [
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              "Name": "Cimetidine-Peripheral Venous Blood-Plasma-Concentration",
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              "CurveOptions": {
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            },
            {
              "Name": "Tiseo 1998 - PO 800 mg QD - Cimetidine - PO - 800 mg - Plasma - agg. (n=19)-Cimetidine-Peripheral Venous Blood-Plasma-ArithmeticMean",
              "X": "Tiseo 1998 - PO 800 mg QD - Cimetidine - PO - 800 mg - Plasma - agg. (n=19)|Time",
              "Y": "Tiseo 1998 - PO 800 mg QD - Cimetidine - PO - 800 mg - Plasma - agg. (n=19)|ObservedData|Peripheral Venous Blood|Plasma|Cimetidine|ArithmeticMean",
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          "Name": "po 800 mg (tab) qd, Tiseo 1998, n=18",
          "Settings": {
            "SideMarginsEnabled": true,
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          "OriginText": "Cimetidine-Model\npo 800 mg (tab) qd, Tiseo 1998, n=18\n2021-09-13 17:11"
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      ]
    }
  ],
  "ParameterIdentifications": [
    {
      "Name": "Parameter Identification",
      "Simulations": [
        "iv 100 mg (5 min), Grahnen 1979, n=3",
        "iv 200 mg (30 min),Morgan 1983, n=4",
        "iv 200 mg (5 min),Morgan 1983, n=6",
        "iv 200 mg, Bodemar 1981, n=10",
        "iv 200 mg, Larsson 1982, n=9",
        "iv 200 mg, Mihaly 1984, n=6",
        "iv 300 mg (2 min), Lebert 1981, n=1",
        "iv 300 mg (2 min), Walkenstein 1978, n=12",
        "po 200 mg (tab), Bodemar 1979 (fasted)",
        "po 200 mg (tab), Bodemar 1979 (fed)",
        "po 200 mg, Bodemar 1981, n=10",
        "po 200 mg, Burland 1975, caps",
        "po 200 mg, Burland 1975, sol",
        "po 200 mg, Kanto 1981, n=8",
        "po 200 mg, Mihaly 1984, n=8",
        "po 200/400 mg QID, Bodemar 1981 (fasted)",
        "po 300 mg (sol), Walkenstein 1978, n=24",
        "po 300 mg (tab), D'Angio 1986, n=6",
        "po 300 mg (tabl), Walkenstein 1978, n=12",
        "po 300 mg QID (sol), Barbhaiya 1995, n=18",
        "po 400 mg (tab), Bodemar 1979, n=10",
        "po 400 mg (tab), Somogyi 1981, n=8",
        "po 400 mg (tab),Grahnen 1979, n=3",
        "po 400 mg, Bodemar 1981, n=9",
        "po 800 mg (tab) qd, Tiseo 1998, n=18",
        "po 800 mg, Bodemar 1981, n=9"
      ],
      "Configuration": {
        "LLOQMode": "OnlyObservedData",
        "RemoveLLOQMode": "NoTrailing",
        "CalculateJacobian": false,
        "Algorithm": {
          "Name": "Levenberg - Marquardt (MPFit)",
          "Properties": [
            {
              "Name": "ftol",
              "Value": 0.001
            },
            {
              "Name": "xtol",
              "Value": 1E-06
            },
            {
              "Name": "gtol",
              "Value": 1E-10
            },
            {
              "Name": "stepfactor",
              "Value": 100.0
            },
            {
              "Name": "maxiter",
              "Value": 200
            },
            {
              "Name": "maxfev",
              "Value": 0
            },
            {
              "Name": "epsfcn",
              "Value": 1E-09
            }
          ]
        }
      },
      "OutputMappings": [
        {
          "Scaling": "Log",
          "Path": "iv 100 mg (5 min), Grahnen 1979, n=3|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "Grahnen 1979 - IV 100 mg, Individual LH - Cimetidine - IV - 100 mg - Plasma - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "iv 100 mg (5 min), Grahnen 1979, n=3|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "Grahnen 1979 - IV 100 mg, Individual KN - Cimetidine - IV - 100 mg - Plasma - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "iv 100 mg (5 min), Grahnen 1979, n=3|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "Grahnen 1979 - IV 100 mg, Individual LOE - Cimetidine - IV - 100 mg - Plasma - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "iv 100 mg (5 min), Grahnen 1979, n=3|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Grahnen 1979 - IV 100 mg, urine mean % of dose - Cimetidine - IV - 100 mg - Urine - agg. (n=10)"
        },
        {
          "Scaling": "Log",
          "Path": "iv 200 mg (30 min),Morgan 1983, n=4|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "Morgan 1983 - IV 200 mg 30 min - Cimetidine - IV - 200 mg - Plasma - agg. (n=4)"
        },
        {
          "Scaling": "Log",
          "Path": "iv 200 mg (5 min),Morgan 1983, n=6|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "Morgan 1983 - IV 200 mg 5 min - Cimetidine - IV - 200 mg - Plasma - agg. (n=6)"
        },
        {
          "Scaling": "Log",
          "Path": "iv 200 mg, Bodemar 1981, n=10|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "Bodemar 1981 - IV 200 mg - Cimetidine - IV - 200 mg - Plasma - agg. (n=10)"
        },
        {
          "Scaling": "Linear",
          "Path": "iv 200 mg, Bodemar 1981, n=10|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Bodemar 1981 - IV 200 mg, Urine - Cimetidine - IV - 200 mg - Urine - agg. (n=10)"
        },
        {
          "Scaling": "Log",
          "Path": "iv 200 mg, Larsson 1982, n=9|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "Larsson 1982 - IV 200 mg in normal renal function group - Cimetidine - IV - 200 mg - Plasma - agg. (n=9)"
        },
        {
          "Scaling": "Linear",
          "Path": "iv 200 mg, Larsson 1982, n=9|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Larsson 1982 - IV 200 mg in normal renal function group - Cimetidine - IV - 200 mg - Urine - agg. (n=9)"
        },
        {
          "Scaling": "Log",
          "Path": "iv 200 mg, Mihaly 1984, n=6|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "Mihaly 1984 - IV 200 mg, beginning of treatment - Cimetidine - IV - 200 mg - Plasma - agg. (n=6)"
        },
        {
          "Scaling": "Log",
          "Path": "iv 300 mg (2 min), Lebert 1981, n=1|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "Lebert 1981 - IV 300 mg - Cimetidine - IV - 300 mg - Plasma - agg. (n=8)"
        },
        {
          "Scaling": "Linear",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - IV 300 mg urine Subject 1 - Cimetidine - IV - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - IV 300 mg urine Subject 2 - Cimetidine - IV - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - IV 300 mg urine Subject 3 - Cimetidine - IV - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - IV 300 mg urine Subject 4 - Cimetidine - IV - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - IV 300 mg urine Subject 5 - Cimetidine - IV - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - IV 300 mg urine Subject 6 - Cimetidine - IV - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - IV 300 mg urine Subject 7 - Cimetidine - IV - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - IV 300 mg urine Subject 8 - Cimetidine - IV - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - IV 300 mg urine Subject 9 - Cimetidine - IV - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - IV 300 mg urine Subject 10 - Cimetidine - IV - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - IV 300 mg urine Subject 11 - Cimetidine - IV - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - IV 300 mg urine Subject 12 - Cimetidine - IV - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - IV 300 mg Subject 1 - Cimetidine - IV - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - IV 300 mg Subject 2 - Cimetidine - IV - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - IV 300 mg Subject 3 - Cimetidine - IV - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - IV 300 mg Subject 4 - Cimetidine - IV - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - IV 300 mg Subject 5 - Cimetidine - IV - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - IV 300 mg Subject 6 - Cimetidine - IV - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - IV 300 mg Subject 7 - Cimetidine - IV - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - IV 300 mg Subject 8 - Cimetidine - IV - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - IV 300 mg Subject 9 - Cimetidine - IV - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - IV 300 mg Subject 10 - Cimetidine - IV - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - IV 300 mg Subject 11 - Cimetidine - IV - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "iv 300 mg (2 min), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - IV 300 mg Subject 12 - Cimetidine - IV - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 200 mg (tab), Bodemar 1979 (fasted)|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Bodemar 1979 - PO 200 mg - Cimetidine - PO - 200 mg - Whole Blood - agg. (n=10)"
        },
        {
          "Scaling": "Log",
          "Path": "po 200 mg (tab), Bodemar 1979 (fasted)|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Bodemar 1979 - PO 200 mg fasted - Cimetidine - PO - 200 mg - Whole Blood - agg. (n=10)"
        },
        {
          "Scaling": "Log",
          "Path": "po 200 mg (tab), Bodemar 1979 (fed)|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Bodemar 1979 - PO 200 mg fed - Cimetidine - PO - 200 mg - Whole Blood - agg. (n=10)"
        },
        {
          "Scaling": "Log",
          "Path": "po 200 mg, Bodemar 1981, n=10|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "Bodemar 1981 - PO 200 mg - Cimetidine - PO - 200 mg - Plasma - agg. (n=10)"
        },
        {
          "Scaling": "Linear",
          "Path": "po 200 mg, Bodemar 1981, n=10|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Bodemar 1981 - PO 200 mg, Urine - Cimetidine - PO - 200 mg - Urine - agg. (n=10)"
        },
        {
          "Scaling": "Log",
          "Path": "po 200 mg, Burland 1975, caps|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Burland 1975 - PO 200 mg caps - Cimetidine - PO - 200 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 200 mg, Burland 1975, sol|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Burland 1975 - PO 200 mg sol - Cimetidine - PO - 200 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 200 mg, Kanto 1981, n=8|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "Kanto 1981 - PO  200 mg - Cimetidine - PO - 200 mg - Plasma - agg. (n=8)"
        },
        {
          "Scaling": "Log",
          "Path": "po 200 mg, Mihaly 1984, n=8|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "Mihaly 1984 - PO 200 mg, beginning of treatment - Cimetidine - PO - 200 mg - Plasma - agg. (n=6)"
        },
        {
          "Scaling": "Log",
          "Path": "po 200/400 mg QID, Bodemar 1981 (fasted)|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "Bodemar 1981 - 200/400 mg QID - Cimetidine - PO - 200/400 mg - Plasma - agg. (n=10)"
        },
        {
          "Scaling": "Linear",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - PO 300 mg urine Subject 1 - Cimetidine - PO - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - PO 300 mg urine Subject 2 - Cimetidine - PO - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - PO 300 mg urine Subject 3 - Cimetidine - PO - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - PO 300 mg urine Subject 4 - Cimetidine - PO - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - PO 300 mg urine Subject 5 - Cimetidine - PO - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - PO 300 mg urine Subject 6 - Cimetidine - PO - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - PO 300 mg urine Subject 7 - Cimetidine - PO - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - PO 300 mg urine Subject 8 - Cimetidine - PO - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - PO 300 mg urine Subject 9 - Cimetidine - PO - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - PO 300 mg urine Subject 10 - Cimetidine - PO - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - PO 300 mg urine Subject 11 - Cimetidine - PO - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Walkenstein 1978 - PO 300 mg urine Subject 12 - Cimetidine - PO - 300 mg - Urine - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 1 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 2 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 3 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 4 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 5 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 6 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 7 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 8 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 9 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 10 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 11 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 12 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 13 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 14 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 15 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 16 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 17 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 18 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 19 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 20 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 21 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 22 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 23 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (sol), Walkenstein 1978, n=24|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg sol Subject 24 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (tab), D'Angio 1986, n=6|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "D'Angio 1986 - PO 300 mg tab subject 1 - Cimetidine - PO - 300 mg - Serum - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (tab), D'Angio 1986, n=6|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "D'Angio 1986 - PO 300 mg tab subject 2 - Cimetidine - PO - 300 mg - Serum - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (tab), D'Angio 1986, n=6|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "D'Angio 1986 - PO 300 mg tab subject 3 - Cimetidine - PO - 300 mg - Serum - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (tab), D'Angio 1986, n=6|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "D'Angio 1986 - PO 300 mg tab subject 4 - Cimetidine - PO - 300 mg - Serum - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (tab), D'Angio 1986, n=6|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "D'Angio 1986 - PO 300 mg tab subject 5 - Cimetidine - PO - 300 mg - Serum - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (tab), D'Angio 1986, n=6|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "D'Angio 1986 - PO 300 mg tab subject 6 - Cimetidine - PO - 300 mg - Serum - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (tabl), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg tab Subject 13 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (tabl), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg tab Subject 14 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (tabl), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg tab Subject 15 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (tabl), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg tab Subject 16 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (tabl), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg tab Subject 17 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (tabl), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg tab Subject 18 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (tabl), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg tab Subject 19 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (tabl), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg tab Subject 20 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (tabl), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg tab Subject 21 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (tabl), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg tab Subject 22 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (tabl), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg tab Subject 23 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg (tabl), Walkenstein 1978, n=12|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Walkenstein 1978 - PO 300 mg tab Subject 24 - Cimetidine - PO - 300 mg - Whole Blood - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 300 mg QID (sol), Barbhaiya 1995, n=18|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "Barbhaiya 1995 - PO 300 mg QID - Cimetidine - PO - 300 mg - Plasma - agg. (n=18)"
        },
        {
          "Scaling": "Log",
          "Path": "po 400 mg (tab), Bodemar 1979, n=10|Organism|PeripheralVenousBlood|Cimetidine|Whole Blood (Peripheral Venous Blood)",
          "ObservedData": "Bodemar 1979 - PO 400 mg - Cimetidine - PO - 400 mg - Whole Blood - agg. (n=10)"
        },
        {
          "Scaling": "Log",
          "Path": "po 400 mg (tab), Somogyi 1981, n=8|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "Somogyi 1981 - PO 400 mg tab - Cimetidine - PO - 400 mg - Plasma - agg. (n=8)"
        },
        {
          "Scaling": "Log",
          "Path": "po 400 mg (tab),Grahnen 1979, n=3|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "Grahnen 1979 - PO 400 mg, Individual LH - Cimetidine - PO - 400 mg - Plasma - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 400 mg (tab),Grahnen 1979, n=3|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "Grahnen 1979 - PO 400 mg, Individual LOE - Cimetidine - PO - 400 mg - Plasma - indiv."
        },
        {
          "Scaling": "Log",
          "Path": "po 400 mg (tab),Grahnen 1979, n=3|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "Grahnen 1979 - PO 400 mg, Individual UB - Cimetidine - PO - 400 mg - Plasma - indiv."
        },
        {
          "Scaling": "Linear",
          "Path": "po 400 mg (tab),Grahnen 1979, n=3|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Grahnen 1979 - PO 400 mg, urine mean % of dose - Cimetidine - PO - 400 mg - Urine - agg. (n=10)"
        },
        {
          "Scaling": "Log",
          "Path": "po 400 mg, Bodemar 1981, n=9|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "Bodemar 1981 - PO 400 mg - Cimetidine - PO - 400 mg - Plasma - agg. (n=9)"
        },
        {
          "Scaling": "Linear",
          "Path": "po 400 mg, Bodemar 1981, n=9|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Bodemar 1981 - PO 400 mg, Urine - Cimetidine - PO - 400 mg - Urine - agg. (n=9)"
        },
        {
          "Scaling": "Log",
          "Path": "po 800 mg (tab) qd, Tiseo 1998, n=18|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "Tiseo 1998 - PO 800 mg QD - Cimetidine - PO - 800 mg - Plasma - agg. (n=19)"
        },
        {
          "Scaling": "Log",
          "Path": "po 800 mg, Bodemar 1981, n=9|Organism|PeripheralVenousBlood|Cimetidine|Plasma (Peripheral Venous Blood)",
          "ObservedData": "Bodemar 1981 - PO 800 mg - Cimetidine - PO - 800 mg - Plasma - agg. (n=9)"
        },
        {
          "Scaling": "Linear",
          "Path": "po 800 mg, Bodemar 1981, n=9|Organism|Kidney|Urine|Cimetidine|Fraction excreted to urine",
          "ObservedData": "Bodemar 1981 - PO 800 mg, Urine - Cimetidine - PO - 800 mg - Urine - agg. (n=9)"
        }
      ],
      "IdentificationParameters": [
        {
          "Name": "kcat OCT1",
          "Scaling": "Log",
          "LinkedParameters": [
            "iv 100 mg (5 min), Grahnen 1979, n=3|Cimetidine|OCT1-Paper|kcat",
            "iv 200 mg (30 min),Morgan 1983, n=4|Cimetidine|OCT1-Paper|kcat",
            "iv 200 mg (5 min),Morgan 1983, n=6|Cimetidine|OCT1-Paper|kcat",
            "iv 200 mg, Bodemar 1981, n=10|Cimetidine|OCT1-Paper|kcat",
            "iv 200 mg, Larsson 1982, n=9|Cimetidine|OCT1-Paper|kcat",
            "iv 200 mg, Mihaly 1984, n=6|Cimetidine|OCT1-Paper|kcat",
            "iv 300 mg (2 min), Lebert 1981, n=1|Cimetidine|OCT1-Paper|kcat",
            "iv 300 mg (2 min), Walkenstein 1978, n=12|Cimetidine|OCT1-Paper|kcat",
            "po 200 mg (tab), Bodemar 1979 (fasted)|Cimetidine|OCT1-Paper|kcat",
            "po 200 mg (tab), Bodemar 1979 (fed)|Cimetidine|OCT1-Paper|kcat",
            "po 200 mg, Bodemar 1981, n=10|Cimetidine|OCT1-Paper|kcat",
            "po 200 mg, Burland 1975, caps|Cimetidine|OCT1-Paper|kcat",
            "po 200 mg, Burland 1975, sol|Cimetidine|OCT1-Paper|kcat",
            "po 200 mg, Kanto 1981, n=8|Cimetidine|OCT1-Paper|kcat",
            "po 200 mg, Mihaly 1984, n=8|Cimetidine|OCT1-Paper|kcat",
            "po 200/400 mg QID, Bodemar 1981 (fasted)|Cimetidine|OCT1-Paper|kcat",
            "po 300 mg (sol), Walkenstein 1978, n=24|Cimetidine|OCT1-Paper|kcat",
            "po 300 mg (tab), D'Angio 1986, n=6|Cimetidine|OCT1-Paper|kcat",
            "po 300 mg (tabl), Walkenstein 1978, n=12|Cimetidine|OCT1-Paper|kcat",
            "po 300 mg QID (sol), Barbhaiya 1995, n=18|Cimetidine|OCT1-Paper|kcat",
            "po 400 mg (tab), Bodemar 1979, n=10|Cimetidine|OCT1-Paper|kcat",
            "po 400 mg (tab), Somogyi 1981, n=8|Cimetidine|OCT1-Paper|kcat",
            "po 400 mg (tab),Grahnen 1979, n=3|Cimetidine|OCT1-Paper|kcat",
            "po 400 mg, Bodemar 1981, n=9|Cimetidine|OCT1-Paper|kcat",
            "po 800 mg (tab) qd, Tiseo 1998, n=18|Cimetidine|OCT1-Paper|kcat",
            "po 800 mg, Bodemar 1981, n=9|Cimetidine|OCT1-Paper|kcat"
          ],
          "Parameters": [
            {
              "Name": "Start value",
              "Value": 10911.84,
              "Unit": "1/min"
            },
            {
              "Name": "MinValue",
              "Value": 327.0,
              "Unit": "1/min"
            },
            {
              "Name": "MaxValue",
              "Value": 327757.510871441,
              "Unit": "1/min"
            }
          ]
        },
        {
          "Name": "kcat OAT3",
          "Scaling": "Log",
          "LinkedParameters": [
            "iv 100 mg (5 min), Grahnen 1979, n=3|Cimetidine|OAT3-Paper|kcat",
            "iv 200 mg (30 min),Morgan 1983, n=4|Cimetidine|OAT3-Paper|kcat",
            "iv 200 mg (5 min),Morgan 1983, n=6|Cimetidine|OAT3-Paper|kcat",
            "iv 200 mg, Bodemar 1981, n=10|Cimetidine|OAT3-Paper|kcat",
            "iv 200 mg, Larsson 1982, n=9|Cimetidine|OAT3-Paper|kcat",
            "iv 200 mg, Mihaly 1984, n=6|Cimetidine|OAT3-Paper|kcat",
            "iv 300 mg (2 min), Lebert 1981, n=1|Cimetidine|OAT3-Paper|kcat",
            "iv 300 mg (2 min), Walkenstein 1978, n=12|Cimetidine|OAT3-Paper|kcat",
            "po 200 mg (tab), Bodemar 1979 (fasted)|Cimetidine|OAT3-Paper|kcat",
            "po 200 mg (tab), Bodemar 1979 (fed)|Cimetidine|OAT3-Paper|kcat",
            "po 200 mg, Bodemar 1981, n=10|Cimetidine|OAT3-Paper|kcat",
            "po 200 mg, Burland 1975, caps|Cimetidine|OAT3-Paper|kcat",
            "po 200 mg, Burland 1975, sol|Cimetidine|OAT3-Paper|kcat",
            "po 200 mg, Kanto 1981, n=8|Cimetidine|OAT3-Paper|kcat",
            "po 200 mg, Mihaly 1984, n=8|Cimetidine|OAT3-Paper|kcat",
            "po 200/400 mg QID, Bodemar 1981 (fasted)|Cimetidine|OAT3-Paper|kcat",
            "po 300 mg (sol), Walkenstein 1978, n=24|Cimetidine|OAT3-Paper|kcat",
            "po 300 mg (tab), D'Angio 1986, n=6|Cimetidine|OAT3-Paper|kcat",
            "po 300 mg (tabl), Walkenstein 1978, n=12|Cimetidine|OAT3-Paper|kcat",
            "po 300 mg QID (sol), Barbhaiya 1995, n=18|Cimetidine|OAT3-Paper|kcat",
            "po 400 mg (tab), Bodemar 1979, n=10|Cimetidine|OAT3-Paper|kcat",
            "po 400 mg (tab), Somogyi 1981, n=8|Cimetidine|OAT3-Paper|kcat",
            "po 400 mg (tab),Grahnen 1979, n=3|Cimetidine|OAT3-Paper|kcat",
            "po 400 mg, Bodemar 1981, n=9|Cimetidine|OAT3-Paper|kcat",
            "po 800 mg (tab) qd, Tiseo 1998, n=18|Cimetidine|OAT3-Paper|kcat",
            "po 800 mg, Bodemar 1981, n=9|Cimetidine|OAT3-Paper|kcat"
          ],
          "Parameters": [
            {
              "Name": "Start value",
              "Value": 3268741.98,
              "Unit": "1/min"
            },
            {
              "Name": "MinValue",
              "Value": 1111.0,
              "Unit": "1/min"
            },
            {
              "Name": "MaxValue",
              "Value": 110821186.8,
              "Unit": "1/min"
            }
          ]
        },
        {
          "Name": "kcat MATE1",
          "Scaling": "Log",
          "LinkedParameters": [
            "iv 100 mg (5 min), Grahnen 1979, n=3|Cimetidine|MATE1-Paper|kcat",
            "iv 200 mg (30 min),Morgan 1983, n=4|Cimetidine|MATE1-Paper|kcat",
            "iv 200 mg (5 min),Morgan 1983, n=6|Cimetidine|MATE1-Paper|kcat",
            "iv 200 mg, Bodemar 1981, n=10|Cimetidine|MATE1-Paper|kcat",
            "iv 200 mg, Larsson 1982, n=9|Cimetidine|MATE1-Paper|kcat",
            "iv 200 mg, Mihaly 1984, n=6|Cimetidine|MATE1-Paper|kcat",
            "iv 300 mg (2 min), Lebert 1981, n=1|Cimetidine|MATE1-Paper|kcat",
            "iv 300 mg (2 min), Walkenstein 1978, n=12|Cimetidine|MATE1-Paper|kcat",
            "po 200 mg (tab), Bodemar 1979 (fasted)|Cimetidine|MATE1-Paper|kcat",
            "po 200 mg (tab), Bodemar 1979 (fed)|Cimetidine|MATE1-Paper|kcat",
            "po 200 mg, Bodemar 1981, n=10|Cimetidine|MATE1-Paper|kcat",
            "po 200 mg, Burland 1975, caps|Cimetidine|MATE1-Paper|kcat",
            "po 200 mg, Burland 1975, sol|Cimetidine|MATE1-Paper|kcat",
            "po 200 mg, Kanto 1981, n=8|Cimetidine|MATE1-Paper|kcat",
            "po 200 mg, Mihaly 1984, n=8|Cimetidine|MATE1-Paper|kcat",
            "po 200/400 mg QID, Bodemar 1981 (fasted)|Cimetidine|MATE1-Paper|kcat",
            "po 300 mg (sol), Walkenstein 1978, n=24|Cimetidine|MATE1-Paper|kcat",
            "po 300 mg (tab), D'Angio 1986, n=6|Cimetidine|MATE1-Paper|kcat",
            "po 300 mg (tabl), Walkenstein 1978, n=12|Cimetidine|MATE1-Paper|kcat",
            "po 300 mg QID (sol), Barbhaiya 1995, n=18|Cimetidine|MATE1-Paper|kcat",
            "po 400 mg (tab), Bodemar 1979, n=10|Cimetidine|MATE1-Paper|kcat",
            "po 400 mg (tab), Somogyi 1981, n=8|Cimetidine|MATE1-Paper|kcat",
            "po 400 mg (tab),Grahnen 1979, n=3|Cimetidine|MATE1-Paper|kcat",
            "po 400 mg, Bodemar 1981, n=9|Cimetidine|MATE1-Paper|kcat",
            "po 800 mg (tab) qd, Tiseo 1998, n=18|Cimetidine|MATE1-Paper|kcat",
            "po 800 mg, Bodemar 1981, n=9|Cimetidine|MATE1-Paper|kcat"
          ],
          "Parameters": [
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              "Name": "Start value",
              "Value": 103.56,
              "Unit": "1/min"
            },
            {
              "Name": "MinValue",
              "Value": 5.759,
              "Unit": "1/min"
            },
            {
              "Name": "MaxValue",
              "Value": 575.9049486992,
              "Unit": "1/min"
            }
          ]
        },
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          "Scaling": "Log",
          "LinkedParameters": [
            "po 200 mg (tab), Bodemar 1979 (fasted)|Cimetidine|Specific intestinal permeability (transcellular)",
            "po 200 mg (tab), Bodemar 1979 (fed)|Cimetidine|Specific intestinal permeability (transcellular)",
            "po 200 mg, Bodemar 1981, n=10|Cimetidine|Specific intestinal permeability (transcellular)",
            "po 200 mg, Burland 1975, caps|Cimetidine|Specific intestinal permeability (transcellular)",
            "po 200 mg, Burland 1975, sol|Cimetidine|Specific intestinal permeability (transcellular)",
            "po 200 mg, Kanto 1981, n=8|Cimetidine|Specific intestinal permeability (transcellular)",
            "po 200 mg, Mihaly 1984, n=8|Cimetidine|Specific intestinal permeability (transcellular)",
            "po 200/400 mg QID, Bodemar 1981 (fasted)|Cimetidine|Specific intestinal permeability (transcellular)",
            "po 300 mg (sol), Walkenstein 1978, n=24|Cimetidine|Specific intestinal permeability (transcellular)",
            "po 300 mg (tab), D'Angio 1986, n=6|Cimetidine|Specific intestinal permeability (transcellular)",
            "po 300 mg (tabl), Walkenstein 1978, n=12|Cimetidine|Specific intestinal permeability (transcellular)",
            "po 300 mg QID (sol), Barbhaiya 1995, n=18|Cimetidine|Specific intestinal permeability (transcellular)",
            "po 400 mg (tab), Bodemar 1979, n=10|Cimetidine|Specific intestinal permeability (transcellular)",
            "po 400 mg (tab), Somogyi 1981, n=8|Cimetidine|Specific intestinal permeability (transcellular)",
            "po 400 mg (tab),Grahnen 1979, n=3|Cimetidine|Specific intestinal permeability (transcellular)",
            "po 400 mg, Bodemar 1981, n=9|Cimetidine|Specific intestinal permeability (transcellular)",
            "po 800 mg (tab) qd, Tiseo 1998, n=18|Cimetidine|Specific intestinal permeability (transcellular)",
            "po 800 mg, Bodemar 1981, n=9|Cimetidine|Specific intestinal permeability (transcellular)"
          ],
          "Parameters": [
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              "Name": "Start value",
              "Value": 2.87E-06,
              "Unit": "cm/min"
            },
            {
              "Name": "MinValue",
              "Value": 2.87E-07,
              "Unit": "cm/min"
            },
            {
              "Name": "MaxValue",
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              "Unit": "cm/min"
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          ]
        },
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          "LinkedParameters": [
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            "iv 200 mg (30 min),Morgan 1983, n=4|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "iv 200 mg (5 min),Morgan 1983, n=6|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "iv 200 mg, Bodemar 1981, n=10|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "iv 200 mg, Larsson 1982, n=9|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "iv 200 mg, Mihaly 1984, n=6|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "iv 300 mg (2 min), Lebert 1981, n=1|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "iv 300 mg (2 min), Walkenstein 1978, n=12|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "po 200 mg (tab), Bodemar 1979 (fasted)|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "po 200 mg (tab), Bodemar 1979 (fed)|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "po 200 mg, Bodemar 1981, n=10|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "po 200 mg, Burland 1975, caps|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "po 200 mg, Burland 1975, sol|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "po 200 mg, Kanto 1981, n=8|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "po 200 mg, Mihaly 1984, n=8|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "po 200/400 mg QID, Bodemar 1981 (fasted)|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "po 300 mg (sol), Walkenstein 1978, n=24|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "po 300 mg (tab), D'Angio 1986, n=6|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "po 300 mg (tabl), Walkenstein 1978, n=12|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "po 300 mg QID (sol), Barbhaiya 1995, n=18|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "po 400 mg (tab), Bodemar 1979, n=10|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "po 400 mg (tab), Somogyi 1981, n=8|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "po 400 mg (tab),Grahnen 1979, n=3|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "po 400 mg, Bodemar 1981, n=9|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "po 800 mg (tab) qd, Tiseo 1998, n=18|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance",
            "po 800 mg, Bodemar 1981, n=9|Cimetidine-Total Hepatic Clearance-Somogyi 1983|Specific clearance"
          ],
          "Parameters": [
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              "Name": "Start value",
              "Value": 0.1600808777,
              "Unit": "1/min"
            },
            {
              "Name": "MinValue",
              "Value": 0.0016,
              "Unit": "1/min"
            },
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