Cardio Vascular Disease Ontology
type: Ontology
version IRI: cvdo.owl
imports: bfo.owl
imports: doid import.owl
imports: fma import.owl
imports: ogms import.owl
creator: Adrien Barton
creator: Arnaud Rosier
creator: Jean-François Ethier
creator: Paul Fabry
license: http://creativecommons.org/licenses/by/4.0/
comment: CVDO is an ontology of cardiovascular diseases structured on OBO foundry’s principle and based on BFO. CVDO reorganizes and completes DOID cardiovascular diseases following OGMS tripartite model of disease, and builds its taxonomy of diseases largely by automatic reasoning.
version info: 2020-03-05

CVDO definition
type: AnnotationProperty
CVDO editor note: This annotation property is created temporarily for better visibility of the distinction between DOID definitions and updated CVDO definition (when a DOID definition of a class did not need to be changed, no additional CVDO definition was included). Ultimately, 'CVDO definition' annotation properties should be replaced by 'definition' annotation properties.
sub property of: IAO_0000115

CVDO editor note
type: AnnotationProperty
comment: This annotation property is created temporarily for better visibility of the CVDO notes, in particular those that concern DOID classes. Ultimately, 'CVDO editor note' annotation properties should be replaced by 'editor note' annotation properties, or removed.
sub property of: IAO_0000116

BFO_0000066
type: ObjectProperty
property chain axiom: BFO_0000082
CVDO editor note: CVDO adds the property chain that if A occurs_in B and B located_in_at_all_times C, then A occurs_in C. This is used for a few inferences in the ontology, but CVDO can be used without problem without this property chain.

bacterial endocarditis
type: Class
subclass of: DOID_0060000
CVDO definition: An endocarditis caused by bacterial infection.

viral endocarditis
type: Class
subclass of: DOID_0060000
CVDO definition: An endocarditis caused by viral infection.

fungal endocarditis
type: Class
subclass of: DOID_0060000
CVDO definition: An endocarditis caused by fungal infection.

heart disorder
type: Class
equivalent class: Class
  intersection of: OGMS_0000045
  intersection of: Restriction
    on property: BFO_0000082
    some values from: FMA 7088
CVDO definition: A disorder located in the heart.

vascular disorder
type: Class
equivalent class: Class
  intersection of: OGMS_0000045
  intersection of: Restriction
    on property: BFO_0000082
    some values from: FMA 3710
CVDO definition: A disorder always located in a blood vessel.

endocardium disorder
type: Class
equivalent class: Class
  intersection of: OGMS_0000045
  intersection of: Restriction
    on property: BFO_0000082
    some values from: FMA 7280
CVDO definition: A disorder always located in the endocardium.

pericardium disorder
type: Class
equivalent class: Class
  intersection of: OGMS_0000045
  intersection of: Restriction
    on property: BFO_0000082
    some values from: FMA 9869
CVDO definition: A disorder always located in the pericardium.
CVDO editor note: Since the pericardium is not a part of the heart according to FMA, pericardium disorder is not classified as a heart disorder.

infectious pericarditis
type: Class
subclass of: DOID 1787
CVDO definition: A pericarditis caused by an infection.

bacterial pericarditis
type: Class
subclass of: infectious pericarditis
CVDO definition: A pericarditis caused by a bacterial infection.

viral pericarditis
type: Class
subclass of: infectious pericarditis
CVDO definition: A pericarditis caused by a viral infection.

fungal pericarditis
type: Class
subclass of: infectious pericarditis
CVDO definition: A pericarditis caused by a fungal infection.

protozoal pericarditis
type: Class
subclass of: infectious pericarditis

heart pathological process
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 7088
CVDO definition: A pathological process involving or occuring in the heart.

pericardium pathological process
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 9869
CVDO definition: A pathological process involving or occuring in the pericardium.

acute pericarditis
type: Class
equivalent class: Class
  intersection of: DOID 1787
  intersection of: Restriction
    on property: BFO_0000054
    some values from: OGMS_0000094
CVDO definition: A pericarditis that has an acute disease course.

chronic pericarditis
type: Class
equivalent class: Class
  intersection of: DOID 1787
  intersection of: Restriction
    on property: BFO_0000054
    some values from: OGMS_0000064
CVDO definition: A pericarditis that has a chronic disease course.

atrioventricular block (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: atrioventricular block (process)
subclass of: Restriction
  on property: BFO_0000113
  some values from: impaired atrioventricular node

first degree atrioventricular block (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: first degree atrioventricular block (process)

Mobitz I second degree atrioventricular block (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: Mobitz I second degree atrioventricular block (process)

third degree atrioventricular block (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: third degree atrioventricular block (process)
has exact synonym: complete heart block

heart conduction disorder
type: Class
equivalent class: Class
  intersection of: OGMS_0000045
  intersection of: Restriction
    on property: BFO_0000082
    some values from: FMA_83378
CVDO definition: A disorder always loacted in the conducting tissue of the heart.

impaired atrioventricular node
type: Class
subclass of: heart conduction disorder

impaired right branch of atrioventricular bundle
type: Class
subclass of: heart conduction disorder

bundle of Kent
type: Class
subclass of: atrioventricular accessory bundle

sinoatrial block (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: sinoatrial block (process)
subclass of: Restriction
  on property: BFO_0000113
  some values from: impaired sinoatrial node

Mobitz I second degree sinoatrial block (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: Mobitz I second degree sinoatrial block (process)
has exact synonym: Wenckebach block

Mobitz II second degree sinoatrial block (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: Mobitz II second degree sinoatrial block (process)
has exact synonym: sinus exit block

first degree sinoatrial block (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: first degree sinoatrial block (process)

third degree sinoatrial block (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: third degree sinoatrial block (process)

impaired sinoatrial node
type: Class
subclass of: heart conduction disorder

heart block (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: heart block (process)

impaired posterior division of left branch of atrioventricular bundle
type: Class
subclass of: heart conduction disorder

left posterior fascicular block (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: left posterior fascicular block (process)
subclass of: Restriction
  on property: BFO_0000113
  some values from: impaired posterior division of left branch of atrioventricular bundle

infra-hisian block (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: infra-hisian block (process)

left bundle branch block (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: left bundle branch block (process)
subclass of: Restriction
  on property: BFO_0000113
  some values from: Class
    intersection of: OGMS_0000045
    intersection of: Restriction
      on property: BFO_0000172
      some values from: impaired posterior division of left branch of atrioventricular bundle
    intersection of: Restriction
      on property: BFO_0000172
      some values from: impaired anterior division of left branch of atrioventricular bundle

cardiac arrhythmia (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: cardiac arrhythmia (process)
CVDO definition: A heart conduction disease characterized by cardiac arrhythmia processes.
CVDO editor note: Usual medical language does not differentiate the disease and the corresponding pathological process for the different kinds of cardiac arrhythmias. CVDO distinguishes them explicitly with the suffix '(disease)' or '(process)'.

atrial fibrillation (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: atrial fibrillation (process)
disjoint union of: permanent atrial fibrillation
disjoint union of: paroxysmal atrial fibrillation
disjoint union of: persistent atrial fibrillation

atrial fibrillation (process)
type: Class
subclass of: supraventricular tachycardia (process)

atrial flutter (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: atrial flutter (process)

common atrial flutter (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: common atrial flutter (process)
has exact synonym: cavotricuspid isthmus dependant macroreentry tachycardia
has exact synonym: type I atrial flutter

cardiac atrium fibrosis
type: Class
subclass of: cardiac atrium pathological process
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA 7099
CVDO definition: A pathological process of fibrosis of the cardiac atrium.

supraventricular tachycardia (process)
type: Class
subclass of: tachycardia (process)

bradycardia (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: bradycardia (process)

bradycardia (process)
type: Class
subclass of: cardiac arrhythmia (process)

premature atrial contraction (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: premature atrial contraction (process)

left anterior fascicle
type: Class
subclass of: FMA 6266

heart valve disorder
type: Class
equivalent class: Class
  intersection of: OGMS_0000045
  intersection of: Restriction
    on property: BFO_0000082
    some values from: FMA 7110
IAO_0000115: A disorder always located in a heart valve.

wandering pacemaker
type: Class
subclass of: DOID_10273
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: cardiac arrhythmia (process)

tricuspid valve disease
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Class
    union of: Restriction
      on property: BFO_0000054
      some values from: Class
        intersection of: OGMS_0000063
        intersection of: Restriction
    union of: Restriction
      on property: BFO_0000113
      some values from: tricuspid valve disorder
CVDO definition: A disease affecting the tricuspid valve of the heart.

myxomatous degenerated structure in a mitral valve leaflet
type: Class
subclass of: degenerated structure in a heart valve leaflet
subclass of: Restriction
  on property: BFO_0000082
  some values from: FMA 7235
IAO_0000115: A degenerated structure in a mitral valve leaflet due to myxomatous proliferation.

heart pathological process involving a heart valve
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 7088
  intersection of: Restriction
    on property: BFO_0000167
    some values from: FMA 7110
CVDO definition: A heart pathological process that has a heart valve as a participant.
CVDO editor note: This class should not be confused with 'heart valve pathological process', which are pathological processes occurring in a heart valve, rather than pathological process having as participant a heart valve.

mitral valve leaflet displacement into the left atrium during left ventricular systole
type: Class
equivalent class: Class
  intersection of: heart valve leaflet displacement into a cardiac chamber
  intersection of: Restriction
    on property: BFO_0000132
    some values from: left ventricular systole
  intersection of: Restriction
    on property: BFO_0000167
    some values from: FMA 7235

tricuspid valve leaflet displacement into the right atrium during right ventricular systole
type: Class
equivalent class: Class
  intersection of: heart valve leaflet displacement into a cardiac chamber
  intersection of: Restriction
    on property: BFO_0000132
    some values from: right ventricular systole
  intersection of: Restriction
    on property: BFO_0000167
    some values from: FMA 7234

aortic valve leaflet displacement into the left ventricle during left ventricular diastole
type: Class
equivalent class: Class
  intersection of: heart valve leaflet displacement into a cardiac chamber
  intersection of: Restriction
    on property: BFO_0000132
    some values from: left ventricular diastole
  intersection of: Restriction
    on property: BFO_0000167
    some values from: FMA 7236

heart valve leaflet displacement into a cardiac chamber during ventricular systole
type: Class
equivalent class: Class
  intersection of: heart valve leaflet displacement into a cardiac chamber
  intersection of: Restriction
    on property: BFO_0000132
    some values from: ventricular systole

mitral valve improper close during left ventricular systole
type: Class
equivalent class: Class
  intersection of: heart valve improper close
  intersection of: Restriction
    on property: BFO_0000132
    some values from: left ventricular systole
  intersection of: Restriction
    on property: BFO_0000167
    some values from: FMA 7235

retrograd blood flow through mitral valve during left ventricular systole
type: Class
subclass of: retrograd blood flow through a heart valve

retrograd blood flow through pulmonary valve during right ventricular diastole
type: Class
subclass of: retrograd blood flow through a heart valve

pulmonary valve improper close during right ventricular diastole
type: Class
equivalent class: Class
  intersection of: heart valve improper close
  intersection of: Restriction
    on property: BFO_0000132
    some values from: right ventricular diastole
  intersection of: Restriction
    on property: BFO_0000167
    some values from: FMA 7246

tricuspid valve improper close during right ventricular systole
type: Class
equivalent class: Class
  intersection of: heart valve improper close
  intersection of: Restriction
    on property: BFO_0000132
    some values from: right ventricular systole
  intersection of: Restriction
    on property: BFO_0000167
    some values from: FMA 7234

aortic valve improper close during left ventricular diastole
type: Class
equivalent class: Class
  intersection of: heart valve improper close
  intersection of: Restriction
    on property: BFO_0000132
    some values from: left ventricular diastole
  intersection of: Restriction
    on property: BFO_0000167
    some values from: FMA 7236

retrograd blood flow through tricuspid valve during right ventricular systole
type: Class
subclass of: retrograd blood flow through a heart valve

retrograd blood flow through aortic valve during left ventricular diastole
type: Class
subclass of: retrograd blood flow through a heart valve

disturbed anterograd blood flow through mitral valve during left ventricular diastole
type: Class
subclass of: disturbed anterograd blood flow through a heart valve

retrograd blood flow through a heart valve
type: Class
subclass of: cardiac blood circulation pathological process

disturbed anterograd blood flow through a heart valve
type: Class
subclass of: cardiac blood circulation pathological process

disturbed anterograd blood flow through tricuspid valve during right ventricular diastole
type: Class
subclass of: disturbed anterograd blood flow through a heart valve

disturbed anterograd blood flow through pulmonary valve during right ventricular systole
type: Class
subclass of: disturbed anterograd blood flow through a heart valve

disturbed anterograd blood flow through aortic valve during left ventricular systole
type: Class
subclass of: disturbed anterograd blood flow through a heart valve

heart valve stenosis
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: heart valve improper opening
  intersection of: Restriction
    on property: BFO_0000113
    some values from: heart valve disorder
CVDO definition: A disease in which some disorder of a heart valve prevents it from opening properly, occasioning disturbance in the anterograd blood flow through the valve.

impaired cardiac output
type: Class
subclass of: cardiac blood circulation pathological process

pressure
type: Class
subclass of: BFO_0000019

blood pressure
type: Class
subclass of: pressure

highly pressured arterial blood flow
type: Class
subclass of: vascular blood circulation pathological process
CVDO definition: A pathological process of highly pressured aerterial blood flow.

heart valve insufficiency
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: heart valve improper close
  intersection of: Restriction
    on property: BFO_0000113
    some values from: heart valve disorder
CVDO definition: A disease in which an abnormal structure in a heart valve prevents it to close propertly, occasioning a retrograd blood flow through the valve.

heart valve improper close
type: Class
subclass of: OGMS_0000061
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA 7088
subclass of: Restriction
  on property: BFO_0000167
  some values from: FMA 7110
CVDO definition: A pathological process of a heart valve closing improperly.

vein disorder
type: Class
equivalent class: Class
  intersection of: OGMS_0000045
  intersection of: Restriction
    on property: BFO_0000082
    some values from: FMA_14284
CVDO definition: A disorder always located in a vein.

vascular pathological process
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 3710
subclass of: OGMS_0000061
CVDO definition: A pathological process involving or occuring in a blood vessel.

thrombosis
type: Class
subclass of: OGMS_0000061
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA 3710
CVDO definition: A pathological process of formation of a blood clot inside a blood vessel, obstructing the flow of blood.

deep vein thrombosis
type: Class
subclass of: thrombosis
CVDO definition: A thrombosis occurring in a deep vein.

artery hardening
type: Class
subclass of: OGMS_0000061
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA_45840
CVDO definition: A pathological process of an artery hardening.

atheromous plaque formation in artery
type: Class
subclass of: OGMS_0000061
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA_50720
CVDO definition: A pathological process of formation of atheromous plaques in an artery.

embolism
type: Class
subclass of: OGMS_0000061
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA 3710
subclass of: Restriction
  on property: BFO_0000167
  some values from: embolus
CVDO definition: A pathological process of lodging of an embolus in a blood vessel.

aneurysm (disorder)
type: Class
subclass of: OGMS_0000045
subclass of: Restriction
  on property: BFO_0000082
  some values from: FMA 3710
CVDO definition: A disorder of localized, blood-filled balloon-like bulge in the wall of a blood vessel.

ischemic disease
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: DOID 326

compression disease
type: Class
subclass of: DOID 178

permanent atrial fibrillation
type: Class
subclass of: atrial fibrillation (disease)
subclass of: Restriction
  on property: BFO_0000054
  some values from: OGMS_0000064
CVDO definition: An atrial fibrillation disease that is characterized by an atrial fibrillation episode longer than 7 days which does not terminate by cardioversion.

right ventricular myocardium dilatation
type: Class
equivalent class: Class
  intersection of: ventricular myocardium dilatation
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 9535
CVDO definition: A pathological process of dilatation of the myocardium of a right cardiac ventricle.

aneurysm rupture
type: Class
subclass of: OGMS_0000061
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA 3710
subclass of: Restriction
  on property: BFO_0000167
  some values from: aneurysm (disorder)
CVDO definition: A pathological process of an aneurysm rupturing.

myocardium disorder
type: Class
equivalent class: Class
  intersection of: OGMS_0000045
  intersection of: Restriction
    on property: BFO_0000082
    some values from: FMA 9462
CVDO definition: A disorder always located in the mycoardium.

Tako Tsubo cardiomyopathy
type: Class
subclass of: DOID_0050700
subclass of: Restriction
  on property: BFO_0000054
  some values from: OGMS_0000066
CVDO definition: A cardiomyopathy whose etiological process includes a stressful or emotional situation, characterized by transient ventricular apical wall motion abnormalities (ballooning).
CVDO editor note: Tako-Tsubo cardiomyopathy is not a dilated cardiomyopathy in Elliott et al.'s (2008) classification.

left ventricular noncompaction
type: Class
subclass of: cardiomyopathy (2008 definition)
CVDO definition: "A cardiomyopathy characterized by prominent left ventricular trabeculae and deep inter-trabecular recesses. The myocardial wall is often thickened with a thin, compacted epicardial layer and a thickened endocardial layer." (Elliott et al., 2008)
has exact synonym: noncompaction cardiomyopathy

genetic hypertrophic cardiomyopathy
type: Class
equivalent class: Class
  intersection of: DOID_11984
  intersection of: Restriction
    on property: BFO_0000113
    some values from: OGMS_0000047
CVDO definition: A hypertrophic cardiomyopathy that has a genetic origin.

pericardium disease
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Class
    union of: Restriction
      on property: BFO_0000054
      some values from: Class
        intersection of: OGMS_0000063
        intersection of: Restriction
    union of: Restriction
      on property: BFO_0000113
      some values from: pericardium disorder
CVDO definition: A disease affecting the pericardium.
CVDO editor note: Since pericardium is not a part of heart according to FMA, pericardium disease is not classified as a heart disease.

vascular disease - unclassified by CVDO
type: Class
subclass of: DOID 178
CVDO editor note: This is a dummy class not intended to be included in CVDO's final version, used to store temporarily DOID's vascular diseases that may be reclassified in the future.

cardiac atrium pathological process
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 7099
CVDO definition: A pathological process occuring in a cardiac atrium.

cardiac ventricle pathological process
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 7100
CVDO definition: A pathological process occurring in a cardiac ventricle.

thromboembolism
type: Class
subclass of: OGMS_0000061
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA 3710
subclass of: Restriction
  on property: BFO_0000117
  some values from: thrombosis
subclass of: Restriction
  on property: BFO_0000117
  some values from: embolism
CVDO definition: A pathological process constituted by a thrombosis (creating a blood clot) and a subsequent embolism (involving the blood clot as the embolus).

infarction
type: Class
subclass of: OGMS_0000061
CVDO definition: A necrosis of a tissue caused by a local lack of oxygen, due to an obstruction of the tissue's blood supply.

pulmonary valve leaflet displacement into the right ventricle during right ventricular diastole
type: Class
equivalent class: Class
  intersection of: heart valve leaflet displacement into a cardiac chamber
  intersection of: Restriction
    on property: BFO_0000132
    some values from: right ventricular diastole
  intersection of: Restriction
    on property: BFO_0000167
    some values from: FMA 7246

cardiac blood circulation pathological process
type: Class
subclass of: OGMS_0000061
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA 7088
CVDO definition: A pathological process involving the blood circuation in the heart.

vascular blood circulation pathological process
type: Class
subclass of: OGMS_0000061
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA 3710
CVDO definition: A pathological process involving the blood circulation in a blood vessel.

part of atrial myocardium with impaired conduction
type: Class
subclass of: OGMS_0000045
subclass of: Restriction
  on property: BFO_0000082
  some values from: FMA 9462

diabetic microangiopathy
type: Class
subclass of: DOID_11713

diabetic macroangiopathy
type: Class
subclass of: DOID_11713

atheromous plaque formation in coronary artery
type: Class
equivalent class: Class
  intersection of: atheromous plaque formation in artery
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA_49893
CVDO definition: A pathological process consisting in the formation of atheromous plaques in a coronary artery. It may lead to a coronary stenosis.

atherosclerotic coronary heart disease
type: Class
equivalent class: Class
  intersection of: DOID 3393
  intersection of: Restriction
    on property: BFO_0000113
    some values from: DOID 4248
CVDO definition: A coronary heart disease due to a coronary stenosis.

left ventricular myocardium dilatation
type: Class
equivalent class: Class
  intersection of: ventricular myocardium dilatation
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 9558
CVDO definition: A pathological process of dilatation of the myocardium of a left cardiac ventricle.

supraventricular tachycardia (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: supraventricular tachycardia (process)

left atrial flutter (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: left atrial flutter (process)
disjoint with: right atrial flutter (disease)

right atrial flutter (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: right atrial flutter (process)

junctional tachycardia (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: junctional tachycardia (process)

atrioventricular nodal reentrant tachycardia (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: atrioventricular nodal reentrant tachycardia (process)

atrial flutter (process)
type: Class
subclass of: supraventricular tachycardia (process)

ventricular fibrillation (process)
type: Class
subclass of: ventricular tachyarrhythmia (process)

junctional tachycardia (process)
type: Class
subclass of: supraventricular tachycardia (process)

premature atrial contraction (process)
type: Class
subclass of: premature contraction (process)

cardiac arrhythmia (process)
type: Class
subclass of: heart conduction pathological process
CVDO definition: A pathological process involving the electrical activity of the heart.

heart block (process)
type: Class
subclass of: cardiac arrhythmia (process)

atrioventricular block (process)
type: Class
subclass of: heart block (process)

infra-hisian block (process)
type: Class
subclass of: heart block (process)

sinoatrial block (process)
type: Class
subclass of: heart block (process)

Mobitz I second degree atrioventricular block (process)
type: Class
subclass of: atrioventricular block (process)

Mobitz II second degree atrioventricular block (process)
type: Class
subclass of: atrioventricular block (process)

first degree atrioventricular block (process)
type: Class
subclass of: atrioventricular block (process)

third degree atrioventricular block (process)
type: Class
subclass of: atrioventricular block (process)

left anterior fascicular block (process)
type: Class
subclass of: infra-hisian block (process)

left bundle branch block (process)
type: Class
subclass of: infra-hisian block (process)

left posterior fascicular block (process)
type: Class
subclass of: infra-hisian block (process)

right bundle branch block (process)
type: Class
subclass of: infra-hisian block (process)

Mobitz I second degree sinoatrial block (process)
type: Class
subclass of: sinoatrial block (process)

Mobitz II second degree sinoatrial block (process)
type: Class
subclass of: sinoatrial block (process)

first degree sinoatrial block (process)
type: Class
subclass of: sinoatrial block (process)

third degree sinoatrial block (process)
type: Class
subclass of: sinoatrial block (process)

coronary artery disorder
type: Class
equivalent class: Class
  intersection of: OGMS_0000045
  intersection of: Restriction
    on property: BFO_0000082
    some values from: FMA_49893
CVDO definition: A disorder always located in a coronary artery.

ventricular myocardium dilatation
type: Class
subclass of: OGMS_0000061
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA_12151
CVDO definition: A pathological process of dilatation of the myocardium of a cardiac ventricle.

ventricular myocardium hypertrophy
type: Class
subclass of: OGMS_0000061
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA_12151
CVDO definition: A pathological process of hypertrophy of the myocardium of a cardiac ventricle.

left ventricular myocardium hypertrophy
type: Class
equivalent class: Class
  intersection of: ventricular myocardium hypertrophy
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 9558
CVDO definition: A pathological process of hypertrophy of the myocardium of a left cardiac ventricle.

right ventricular myocardium hypertrophy
type: Class
equivalent class: Class
  intersection of: ventricular myocardium hypertrophy
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 9535
CVDO definition: A pathological process of hypertrophy of the myocardium of a right cardiac ventricle.

pathological inflammation process
type: Class
subclass of: OGMS_0000061
CVDO definition: A pathological process of an organ or part of organ getting inflamed.

inflammation process in a myocardium
type: Class
equivalent class: Class
  intersection of: pathological inflammation process
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 9462
CVDO definition: An inflammation process occurring in the myocardium.

inflammation process in an endocardium
type: Class
equivalent class: Class
  intersection of: pathological inflammation process
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 7280
CVDO definition: An inflammation process occurring in the endocardium.

inflammation process in a pericardium
type: Class
equivalent class: Class
  intersection of: pathological inflammation process
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 9869
CVDO definition: An inflammation process occurring in the pericardium.

inflammation process in aorta
type: Class
equivalent class: Class
  intersection of: pathological inflammation process
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 3734
CVDO definition: An inflammation process occurring in the aorta.

inflammation process in a blood vessel
type: Class
equivalent class: Class
  intersection of: pathological inflammation process
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 3710
CVDO definition: An inflammation process in a blood vessel.

inflammation process in a femoral vein
type: Class
equivalent class: Class
  intersection of: pathological inflammation process
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA_21185
CVDO definition: An inflammation process occurring in the femoral vein.

inflammation process in an iliac vein
type: Class
equivalent class: Class
  intersection of: pathological inflammation process
  intersection of: Class
    union of: Restriction
      on property: BFO_0000066
      some values from: FMA_14333
    union of: Restriction
      on property: BFO_0000066
      some values from: FMA_18883
    union of: Restriction
      on property: BFO_0000066
      some values from: FMA_18884
CVDO definition: An inflammation process occurring in an iliac vein.

inflammation process in a retinal artery
type: Class
equivalent class: Class
  intersection of: pathological inflammation process
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA_49879
CVDO definition: An inflammation of the retinal artery.

inflammation process in a vein
type: Class
equivalent class: Class
  intersection of: pathological inflammation process
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA_50723
CVDO definition: An inflammation process occurring in a vein.

fibrofatty replacement in a right ventricular myocardium
type: Class
subclass of: OGMS_0000061
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA 7098
subclass of: Restriction
  on property: BFO_0000167
  some values from: FMA 9535
comment: A pathological process of fibrofatty replacement in the myocardium of the right cardiac ventricle.

degenerated structure in a heart valve leaflet
type: Class
subclass of: OGMS_0000045
subclass of: Restriction
  on property: BFO_0000082
  some values from: FMA 7110
IAO_0000115: A disorder of degenerated structure in a heart valve leaflet.

degenerated structure in an aortic valve leaflet
type: Class
equivalent class: Class
  intersection of: degenerated structure in a heart valve leaflet
  intersection of: Restriction
    on property: BFO_0000082
    some values from: FMA 7236
CVDO definition: A disorder of degenerated structure in an aortic valve leaflet.

degenerated structure in a mitral valve leaflet
type: Class
equivalent class: Class
  intersection of: degenerated structure in a heart valve leaflet
  intersection of: Restriction
    on property: BFO_0000082
    some values from: FMA 7235
CVDO definition: A disorder of degenerated structure in a mitral valve leaflet.

degenerated structure in a tricuspid valve leaflet
type: Class
equivalent class: Class
  intersection of: degenerated structure in a heart valve leaflet
  intersection of: Restriction
    on property: BFO_0000082
    some values from: FMA 7234
CVDO definition: A (clinically abnormal) degenerated structure in a tricuspid valve leaflet.

degenerated structure in a pulmonary valve leaflet
type: Class
equivalent class: Class
  intersection of: degenerated structure in a heart valve leaflet
  intersection of: Restriction
    on property: BFO_0000082
    some values from: FMA 7246
CVDO definition: A disorder of degenerated structure in a pulmonary valve leaflet.

Barlow's syndrome
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: mitral valve leaflet displacement into the left atrium during left ventricular systole
  intersection of: Restriction
    on property: BFO_0000113
    some values from: myxomatous degenerated structure in a mitral valve leaflet
CVDO definition: A mitral valve prolapse due to myxomatous proliferation in the mitral valve.

fluid accumulation in the pericardial cavity
type: Class
subclass of: OGMS_0000061
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA 9869
CVDO definition: A pathological process consisting in the abnormal accumulation of fluid in the pericardial cavity.
CVDO editor note: A process of pericardial effusion leads to the disorder 'fluid in the pericardial cavity'.

atherosclerotic ischemic cardiomyopathy
type: Class
subclass of: ischemic cardiomyopathy
subclass of: Restriction
  on property: BFO_0000113
  some values from: DOID 4248
CVDO definition: An ischemic cardiomyopathy due to coronary stenosis.

paroxysmal atrial fibrillation
type: Class
subclass of: atrial fibrillation (disease)
CVDO definition: An atrial fibrillation disease that is characterized by an atrial fibrillation episode shorter than 7 days.

persistent atrial fibrillation
type: Class
subclass of: atrial fibrillation (disease)
CVDO definition: An atrial fibrillation disease that is characterized by an atrial fibrillation episode longer than 7 days which does terminate by cardioversion.

premature contraction (process)
type: Class
subclass of: cardiac arrhythmia (process)

premature junctional contraction (process)
type: Class
subclass of: premature contraction (process)

premature ventricular contraction (process)
type: Class
subclass of: premature contraction (process)

sinoatrial arrest (process)
type: Class
subclass of: cardiac arrhythmia (process)
has exact synonym: sinus pause

sinus bradycardia (process)
type: Class
subclass of: bradycardia (process)

tachycardia (process)
type: Class
subclass of: cardiac arrhythmia (process)
has exact synonym: tachyarrhythmia (process)

left atrial flutter (process)
type: Class
subclass of: atrial flutter (process)

right atrial flutter (process)
type: Class
subclass of: atrial flutter (process)

common atrial flutter (process)
type: Class
subclass of: right atrial flutter (process)

atrioventricular nodal reentrant tachycardia (process)
type: Class
subclass of: junctional tachycardia (process)

ventricular tachycardia (process)
type: Class
subclass of: ventricular tachyarrhythmia (process)

monomorphic ventricular tachycardia (process)
type: Class
subclass of: ventricular tachycardia (process)

torsades de pointes (process)
type: Class
subclass of: ventricular tachycardia (process)

ventricular flutter (process)
type: Class
subclass of: ventricular tachycardia (process)

inappropriate sinus tachycardia (process)
type: Class
subclass of: tachycardia (process)

ventricular preexcitation (process)
type: Class
subclass of: anomalous atrioventricular excitation (process)

coronary artery hardening
type: Class
equivalent class: Class
  intersection of: artery hardening
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA_49893
CVDO definition: A pathological process of a coronary artery hardening.

accessory bundle
type: Class
subclass of: heart disorder

atrioventricular accessory bundle
type: Class
subclass of: accessory bundle
CVDO definition: Accessory bundle that connects the atrium to a ventricle outside of the regular atrioventricular conduction system.

impaired sinus node
type: Class
subclass of: heart conduction disorder

tachycardia-bradycardia syndrome
type: Class
subclass of: DOID_13884
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: atrial fibrillation (process)
IAO_0000115: A sick sinus syndrome characterized by sinus pauses and/or bradycardia episodes alternating with sinus or atrial tachycardia episodes.

inappropriate sinus tachycardia (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: inappropriate sinus tachycardia (process)

cardiac channelopathy
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000113
    some values from: cardiac ion channels disorder
CVDO definition: A disease cause by a cardiac ion channel disorder.

long QT syndrome
type: Class
subclass of: cardiac channelopathy
CVDO definition: A cardiac channelopathy in which delayed repolarization of the heart following a heartbeat increases the risk of episodes of torsades de pointes. This is a rare disease.

genetic cardiac channelopathy
type: Class
equivalent class: Class
  intersection of: cardiac channelopathy
  intersection of: Restriction
    on property: BFO_0000113
    some values from: OGMS_0000047
CVDO definition: A cardiac channelopathy that has a genetic origin.

sinus bradycardia (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: sinus bradycardia (process)

left bundle branch block (process)
type: Class
subclass of: left anterior fascicular block (process)

tachycardia (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: tachycardia (process)
has exact synonym: tachyarrhythmia (disease)

sinoatrial arrest (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: sinoatrial arrest (process)

atrioventricular reciprocating tachycardia (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: atrioventricular reciprocating tachycardia (process)

ventricular tachycardia (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: ventricular tachycardia (process)

ventricular flutter (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: ventricular flutter (process)

torsades de pointes (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: torsades de pointes (process)

monomorphic ventricular tachycardia (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: monomorphic ventricular tachycardia (process)

ventricular fibrillation (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: ventricular fibrillation (process)

ventricular tachyarrhythmia (process)
type: Class
subclass of: tachycardia (process)

atrioventricular reciprocating tachycardia (process)
type: Class
subclass of: junctional tachycardia (process)

premature contraction (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: premature contraction (process)

premature junctional contraction (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: premature junctional contraction (process)

premature ventricular contraction (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: premature ventricular contraction (process)

cardiac chamber pathological process
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 7095
CVDO definition: A pathological process occurring in a cardiac chamber.

mitral valve disorder
type: Class
equivalent class: Class
  intersection of: OGMS_0000045
  intersection of: Restriction
    on property: BFO_0000082
    some values from: FMA 7235
CVDO definition: A disorder always located in the mitral valve.

aortic valve disorder
type: Class
equivalent class: Class
  intersection of: OGMS_0000045
  intersection of: Restriction
    on property: BFO_0000082
    some values from: FMA 7236
CVDO definition: A disorder always located in the aortic valve.

tricuspid valve disorder
type: Class
equivalent class: Class
  intersection of: OGMS_0000045
  intersection of: Restriction
    on property: BFO_0000082
    some values from: FMA 7234
CVDO definition: A disorder always located in the tricuspid valve.

pulmonary valve disorder
type: Class
equivalent class: Class
  intersection of: OGMS_0000045
  intersection of: Restriction
    on property: BFO_0000082
    some values from: FMA 7246
CVDO definition: A disorder always located in the pulmonary valve.

heart valve improper opening
type: Class
subclass of: OGMS_0000061
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA 7088
subclass of: Restriction
  on property: BFO_0000167
  some values from: FMA 7110
IAO_0000115: A pathological process of a heart valve improper opening.

aortic valve improper opening during left ventricular systole
type: Class
equivalent class: Class
  intersection of: heart valve improper opening
  intersection of: Restriction
    on property: BFO_0000132
    some values from: left ventricular systole
  intersection of: Restriction
    on property: BFO_0000167
    some values from: FMA 7236

mitral valve narrowed opening during left ventricular diastole
type: Class
equivalent class: Class
  intersection of: heart valve improper opening
  intersection of: Restriction
    on property: BFO_0000132
    some values from: left ventricular diastole
  intersection of: Restriction
    on property: BFO_0000167
    some values from: FMA 7235

pulmonary valve narrowed opening during right ventricular systole
type: Class
equivalent class: Class
  intersection of: heart valve improper opening
  intersection of: Restriction
    on property: BFO_0000132
    some values from: right ventricular systole
  intersection of: Restriction
    on property: BFO_0000167
    some values from: FMA 7246

tricuspid valve narrowed opening during right ventricular diastole
type: Class
equivalent class: Class
  intersection of: heart valve improper opening
  intersection of: Restriction
    on property: BFO_0000132
    some values from: right ventricular diastole
  intersection of: Restriction
    on property: BFO_0000167
    some values from: FMA 7234

coronary heart disease with stable angina
type: Class
equivalent class: Class
  intersection of: DOID 3393
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: stable angina pectoris
IAO_0000115: A coronary heart disease leading to stable angina.

atherosclerotic acute coronary syndrome
type: Class
equivalent class: Class
  intersection of: DOID 8805
  intersection of: Restriction
    on property: BFO_0000113
    some values from: DOID 4248
CVDO definition: An acute coronary syndrome due to coronary stenosis.

angina pectoris
type: Class
subclass of: heart ischemia
disjoint union of: stable angina pectoris
disjoint union of: unstable angina pectoris
CVDO definition: A heart ischemia accompanied by pain.
CVDO editor note: Angina pectoris is sometimes taken to refer to the pain itself, rather than to the pathological process behind it.

stable angina pectoris
type: Class
subclass of: angina pectoris
CVDO definition: An angina that is not unstable.

unstable angina pectoris
type: Class
subclass of: angina pectoris
subclass of: Restriction
  on property: BFO_0000132
  some values from: Class
    intersection of: OGMS_0000094
    intersection of: Restriction
      on property: BFO_0000055
      some values from: DOID 8805
CVDO definition: An angina that worsens. It has at least one of these three features: 1. it occurs at rest (or with minimal exertion), usually lasting >10 min 2. it is severe and of new onset (i.e., within the prior 4–6 weeks) 3. it occurs with a crescendo pattern (i.e., distinctly more severe, prolonged, or frequent than before).

heart pathological process involving a mitral valve
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 7088
  intersection of: Restriction
    on property: BFO_0000167
    some values from: FMA 7235
IAO_0000115: A heart pathological process that has a mitral valve as a participant.

heart pathological process involving an aortic valve
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 7088
  intersection of: Restriction
    on property: BFO_0000167
    some values from: FMA 7236
CVDO definition: A heart pathological process that has an aortic valve as a participant.

heart pathological process involving a tricuspid valve
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 7088
  intersection of: Restriction
    on property: BFO_0000167
    some values from: FMA 7234
IAO_0000115: A heart pathological process that has a tricuspid valve as a participant.

heart pathological process involving a pulmonary valve
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 7088
  intersection of: Restriction
    on property: BFO_0000167
    some values from: FMA 7246
IAO_0000115: A heart pathological process that has a pulmonary valve as a participant.

heart valve leaflet displacement into a cardiac chamber during ventricular diastole
type: Class
equivalent class: Class
  intersection of: heart valve leaflet displacement into a cardiac chamber
  intersection of: Restriction
    on property: BFO_0000132
    some values from: ventricular diastole

ventricular systole
type: Class
subclass of: heart bodily process
subclass of: Restriction
  on property: BFO_0000167
  some values from: FMA 7100

ventricular diastole
type: Class
subclass of: heart bodily process
subclass of: Restriction
  on property: BFO_0000167
  some values from: FMA 7100

atrial systole
type: Class
subclass of: heart bodily process

atrial diastole
type: Class
subclass of: heart bodily process

left ventricular diastole
type: Class
subclass of: ventricular diastole
subclass of: Restriction
  on property: BFO_0000167
  some values from: FMA 7101

right ventricular diastole
type: Class
subclass of: ventricular diastole
subclass of: Restriction
  on property: BFO_0000167
  some values from: FMA 7098

left ventricular systole
type: Class
subclass of: ventricular systole
subclass of: Restriction
  on property: BFO_0000167
  some values from: FMA 7101

right ventricular systole
type: Class
subclass of: ventricular systole
subclass of: Restriction
  on property: BFO_0000167
  some values from: FMA 7098

left atrial systole
type: Class
subclass of: atrial systole

right atrial systole
type: Class
subclass of: atrial systole

left atrial diastole
type: Class
subclass of: atrial diastole

right atrial diastole
type: Class
subclass of: atrial diastole

heart valve leaflet displacement into a cardiac chamber
type: Class
subclass of: heart valve improper close
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA 7088
subclass of: Restriction
  on property: BFO_0000167
  some values from: FMA 7110
IAO_0000115: A pathological process of a heart valve being displaced into a cardiac chamber.

fluid in the pericardial cavity
type: Class
subclass of: OGMS_0000045
subclass of: Restriction
  on property: BFO_0000082
  some values from: FMA 9869
CVDO definition: A disorder of fluid in the pericardial cavity.

blood in the pericardial cavity
type: Class
subclass of: fluid in the pericardial cavity
CVDO definition: A disorder of blood in the pericardial cavity.

heart conduction pathological process
type: Class
subclass of: OGMS_0000061
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA_83378

anomalous atrioventricular excitation (process)
type: Class
subclass of: cardiac arrhythmia (process)

ventricular preexcitation (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: ventricular preexcitation (process)

cardiac ion channels disorder
type: Class
subclass of: heart conduction disorder
CVDO definition: A disorder in the heart conduction system that causes a disturbed function of ion channel subunits or the proteins that regulate them.

pulmonary valve prolapse
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: pulmonary valve leaflet displacement into the right ventricle during right ventricular diastole
  intersection of: Restriction
    on property: BFO_0000113
    some values from: degenerated structure in a pulmonary valve leaflet
CVDO definition: A disease characterized by the displacement of a degenerated pulmonary valve leaflet into the right ventricle during diastole.

impaired anterior division of left branch of atrioventricular bundle
type: Class
subclass of: heart conduction disorder

ventricular tachyarrhythmia (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: ventricular tachyarrhythmia (process)

inflammation process in a heart valve
type: Class
equivalent class: Class
  intersection of: pathological inflammation process
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 7110
CVDO definition: An inflammation process occurring in a heart valve.

heart bodily process
type: Class
subclass of: OGMS_0000060

genetic dilated cardiomyopathy
type: Class
equivalent class: Class
  intersection of: DOID_12930
  intersection of: Restriction
    on property: BFO_0000113
    some values from: OGMS_0000047
CVDO definition: A dilated cardiomyopathy that has a genetic origin.

genetic cardiomyopathy
type: Class
equivalent class: Class
  intersection of: cardiomyopathy (2008 definition)
  intersection of: Restriction
    on property: BFO_0000113
    some values from: OGMS_0000047
CVDO definition: A cardiomyopathy (2008) that has a genetic origin.

embolus
type: Class
subclass of: OGMS_0000045
subclass of: Restriction
  on property: BFO_0000082
  some values from: FMA 3710
comment: A disorder made of a detached, traveling intravascular matter (solid, liquid, or gaseous) carried by circulation. It is capable of creating an arterial occlusion at a site distant from its point of origin.

inflammatory disease
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: pathological inflammation process
CVDO definition: A disease characterized by an inflammation process.

myocardium pathological process
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 9462
comment: A pathological process occurring in the myocardium.

aorta pathological process
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 3734
subclass of: OGMS_0000061
CVDO definition: A pathological process involving or occuring in the aorta.

aorta disorder
type: Class
equivalent class: Class
  intersection of: OGMS_0000045
  intersection of: Restriction
    on property: BFO_0000082
    some values from: FMA 3734
CVDO definition: A disorder always located in the aorta.

endocardium pathological process
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 7280
subclass of: OGMS_0000061
CVDO definition: A pathological process occuring in the endocardium.

endocardium thickening
type: Class
subclass of: OGMS_0000061
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA 7280
CVDO definition: A pathological process of thickening of the endocardium.

endocardium disease
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Class
    union of: Restriction
      on property: BFO_0000054
      some values from: Class
        intersection of: OGMS_0000063
        intersection of: Restriction
    union of: Restriction
      on property: BFO_0000113
      some values from: endocardium disorder
comment: A disease affecting the endocardium.

left ventricle disorder
type: Class
equivalent class: Class
  intersection of: OGMS_0000045
  intersection of: Restriction
    on property: BFO_0000082
    some values from: FMA 7101
CVDO definition: A disorder always located in the left heart ventricle.

right ventricle disorder
type: Class
equivalent class: Class
  intersection of: OGMS_0000045
  intersection of: Restriction
    on property: BFO_0000082
    some values from: FMA 7098
CVDO definition: A disorder always located in the right heart ventricle.

heart ventricle disorder
type: Class
equivalent class: Class
  intersection of: OGMS_0000045
  intersection of: Restriction
    on property: BFO_0000082
    some values from: FMA 7100
CVDO definition: A disorder always located in a heart ventricle.

heart ischemia
type: Class
subclass of: DOID 326
CVDO definition: An ischemia of the heart.

vein pathological process
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA_50723

ischemic cardiomyopathy
type: Class
subclass of: DOID 3394
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: left ventricular myocardium dilatation
    intersection of: Restriction
      on property: BFO_0000117
      some values from: left ventricular myocardium contraction dysfunctional process
CVDO definition: An ischemic heart disease leading to a dilatation and dysfunction of the left ventricle.

material anatomical entity disorder
type: Class
equivalent class: Class
  intersection of: OGMS_0000045
  intersection of: Restriction
    on property: BFO_0000082
    some values from: FMA_67165
comment: A disorder located in an anatomical entity.

material anatomical entity pathological process
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA_67165

cardiovascular system disorder
type: Class
equivalent class: Class
  intersection of: OGMS_0000045
  intersection of: Restriction
    on property: BFO_0000082
    some values from: FMA 7161
subclass of: OGMS_0000045

cardiovascular system pathological process
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 7161
subclass of: OGMS_0000061

disease of material anatomical entity
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Class
    union of: Restriction
      on property: BFO_0000054
      some values from: Class
        intersection of: OGMS_0000063
        intersection of: Restriction
    union of: Restriction
      on property: BFO_0000113
      some values from: material anatomical entity disorder
subclass of: OGMS_0000031
comment: A disease that affects a material anatomical entity.

valvular cardiomyopathy
type: Class
subclass of: OGMS_0000031
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000065
    intersection of: Class
      union of: Restriction
        on property: BFO_0000117
        some values from: left ventricular myocardium dilatation
      union of: Restriction
        on property: BFO_0000117
        some values from: left ventricular myocardium hypertrophy
    intersection of: Restriction
      on property: BFO_0000117
      some values from: aortic valve improper opening during left ventricular systole
    intersection of: Restriction
      on property: BFO_0000117
      some values from: left ventricular myocardium contraction dysfunctional process
subclass of: Restriction
  on property: BFO_0000113
  some values from: aortic valve disorder
CVDO definition: An aortic valve stenosis leading to a hypertrophy or dilatation of the left ventricle and its dysfunction.

cardiomyopathy (2008 definition)
type: Class
subclass of: OGMS_0000031
CVDO definition: A heart disease in which the heart muscle is structurally and functionally abnormal, in the absence of coronary artery disease, hypertension, valvular disease and congenital heart disease sufficient to cause the observed myocardial abnormality. (adapted from Elliott et al., 2008, European Heart Journal, 29, 270-276)
CVDO editor note: Contemporary (e.g. Elliott et al. 2008) definitions of cardiomyopathy exclude ischemic cardiomyopathy, hypertensive cardiomyopathy and valvular cardiomyopathy.

left ventricular myocardium contraction dysfunctional process
type: Class
equivalent class: Class
  intersection of: myocardium contraction dysfunctional process
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 9558

myocardium contraction dysfunctional process
type: Class
subclass of: OGMS_0000061
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA 9462

left ventricle pathological process
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 7101
CVDO editor note: A pathological process occurring in the left heart ventricle.

right ventricle pathological process
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 7098
CVDO definition: A pathological process occurring in the right heart ventricle.

inflammatory dilated cardiomyopathy
type: Class
subclass of: DOID_12930
CVDO definition: "Inflammatory DCM is defined by the presence of chronic inflammatory cells in association with left ventricular dilatation and reduced ejection fraction". (Elliott et al., 2008)
has exact synonym: inflammatory dilated cardiomyopathy

hypertensive cardiomyopathy
type: Class
subclass of: DOID_11516
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: left ventricular myocardium hypertrophy
    intersection of: Restriction
      on property: BFO_0000117
      some values from: left ventricular myocardium contraction dysfunctional process
CVDO definition: A hypertensive heart disease leading to a hypertrophy and dysfunction of the left ventricle.

congenital heart disease
type: Class
subclass of: DOID 114
CVDO definition: A heart disease existing at birth, or developping during the first month after birth.

heart ventricle disease
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Class
    union of: Restriction
      on property: BFO_0000054
      some values from: Class
        intersection of: OGMS_0000063
        intersection of: Restriction
    union of: Restriction
      on property: BFO_0000113
      some values from: heart ventricle disorder
subclass of: OGMS_0000031
CVDO definition: A disease affecting a heart ventricle.

left ventricle disease
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Class
    union of: Restriction
      on property: BFO_0000054
      some values from: Class
        intersection of: OGMS_0000063
        intersection of: Restriction
    union of: Restriction
      on property: BFO_0000113
      some values from: left ventricle disorder
subclass of: OGMS_0000031
CVDO definition: A disease affecting a heart left ventricle.

right ventricle disease
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Class
    union of: Restriction
      on property: BFO_0000054
      some values from: Class
        intersection of: OGMS_0000063
        intersection of: Restriction
    union of: Restriction
      on property: BFO_0000113
      some values from: right ventricle disorder
subclass of: OGMS_0000031
CVDO definition: A disease affecting a heart right ventricle.

ventricular myocardium contraction dysfunctional process
type: Class
equivalent class: Class
  intersection of: myocardium contraction dysfunctional process
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA_12151

right ventricular myocardium contraction dysfunctional process
type: Class
equivalent class: Class
  intersection of: myocardium contraction dysfunctional process
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 9535
subclass of: myocardium contraction dysfunctional process

myocardium of left ventricle stiffening
type: Class
subclass of: OGMS_0000061
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA 9558

heart valve pathological process
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 7110
CVDO definition: A pathological process occurring in a heart valve.

aortic valve pathological process
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 7236
subclass of: OGMS_0000061
CVDO definition: A pathological process occurring in an aortic valve.

mitral valve pathological process
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 7235
CVDO definition: A pathological process occurring in a mitral valve.

tricuspid valve pathological process
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 7234
CVDO definition: A pathological process occurring in a tricuspid valve.

pulmonary valve pathological process
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 7246
CVDO definition: A pathological process occurring in a pulmonary valve.

myocardium disease
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Class
    union of: Restriction
      on property: BFO_0000054
      some values from: Class
        intersection of: OGMS_0000063
        intersection of: Restriction
    union of: Restriction
      on property: BFO_0000113
      some values from: myocardium disorder
subclass of: OGMS_0000031
CVDO definition: A disease affecting the myocardium.

genetic heart disease
type: Class
equivalent class: Class
  intersection of: DOID 114
  intersection of: Restriction
    on property: BFO_0000113
    some values from: OGMS_0000047
CVDO definition: A heart disease that has a genetic disorder.

congenital disease
type: Class
subclass of: OGMS_0000031
CVDO definition: A disease existing at birth, or developping during the first month after birth.

coronary artery pathological process
type: Class
equivalent class: Class
  intersection of: OGMS_0000061
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA_49893

coronary artery smooth muscle constriction
type: Class
subclass of: OGMS_0000061
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA_49893
CVDO editor note: A pathological process of coronary artery smooth muscle constriction.

DOID_0050431
type: Class
subclass of: OGMS_0000031
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000065
    intersection of: Restriction
      on property: BFO_0000117
      some values from: fibrofatty replacement in a right ventricular myocardium
    intersection of: Restriction
      on property: BFO_0000117
      some values from: right ventricular myocardium contraction dysfunctional process
subclass of: Restriction
  on property: BFO_0000113
  some values from: OGMS_0000047
CVDO definition: A cardiomyopathy characterized by adipose and fibrosis infiltration in the right ventricular myocardium. It is caused by genetic defects of desmosomes (which are parts of the myocardium) and may result in arrhythmia.

DOID_0050451
type: Class
subclass of: cardiac channelopathy
subclass of: Restriction
  on property: BFO_0000113
  some values from: OGMS_0000047
subclass of: Restriction
  on property: BFO_0000054
  all values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: ventricular tachyarrhythmia (process)
CVDO definition: A heart conduction disease that is characterised by abnormal electrocardiogram (ECG) findings and an increased risk of sudden cardiac death by ventricular tachyarrhytmia.

familial atrial fibrillation
type: Class
subclass of: atrial fibrillation (disease)
subclass of: Restriction
  on property: BFO_0000113
  some values from: OGMS_0000047
CVDO definition: An atrial fibrillation disease that has a genetic origin.

DOID_0050700
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: ventricular myocardium contraction dysfunctional process
disjoint union of: cardiomyopathy (2008 definition)
disjoint union of: Class
  intersection of: congenital heart disease
  intersection of: DOID_0050700
disjoint union of: Class
  intersection of: DOID_0050700
  intersection of: DOID_11516
disjoint union of: Class
  intersection of: DOID_0050700
  intersection of: DOID 3393
disjoint union of: Class
  intersection of: DOID_0050700
  intersection of: DOID 4079
CVDO definition: Disease of the myocardium associated with cardiac dysfunction. (Report of the 1995 World Health Organization/International Society and Federation of Cardiology Task Force on the Definition and Classification of Cardiomyopathies)
CVDO editor note: DOID label "cardiomyopathy" was changed.

DOID_0060000
type: Class
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: inflammation process in an endocardium
CVDO definition: An endocarditis caused by infection.

non-bacterial thrombotic endocarditis
type: Class
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: inflammation process in an endocardium
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: inflammation process in a heart valve
CVDO editor note: DOID label 'marantic endocarditis' was changed in CVDO (non-bacterial thrombotic endocarditis is a more common name).
has exact synonym: marantic endocarditis

left anterior fascicular block (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: left anterior fascicular block (process)
subclass of: Restriction
  on property: BFO_0000113
  some values from: impaired anterior division of left branch of atrioventricular bundle
CVDO editor note: DOID label changed to 'left anterior fascicular block (disease)' for symmetry reasons with 'left posterior fascicular block (disease)'

DOID_10273
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Class
    union of: Restriction
      on property: BFO_0000054
      some values from: Class
        intersection of: OGMS_0000063
        intersection of: Restriction
    union of: Restriction
      on property: BFO_0000113
      some values from: heart conduction disorder
CVDO definition: A disease affecting the conducting tissue of the heart.

DOID_10314
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: inflammation process in an endocardium
CVDO definition: A disease characterized by an inflammation of the endocardium.

DOID_10392
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: anomalous atrioventricular excitation (process)
CVDO editor note: DOID label 'anomalous atrioventricular excitation' was changed.

Mobitz II second degree atrioventricular block (disease)
type: Class
equivalent class: Class
  intersection of: DOID_10273
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: Mobitz II second degree atrioventricular block (process)
CVDO editor note: DOID label changed for homogeneization reasons.

DOID 114
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Class
    union of: Restriction
      on property: BFO_0000054
      some values from: Class
        intersection of: OGMS_0000063
        intersection of: Restriction
    union of: Restriction
      on property: BFO_0000113
      some values from: heart disorder
CVDO definition: A disease affecting the heart.

DOID 115
type: Class
subclass of: OGMS_0000031
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: heart pathological process
subclass of: Restriction
  on property: BFO_0000113
  some values from: fluid in the pericardial cavity
CVDO definition: A disease caused by the presence of fluid in the pericardial cavity (due to pericardial effusion), affecting negatively the heart's pumping function.
CVDO editor note: In CVDO, cardiac tamponade is defined as *being caused* by a pericardial effusion, rather than as *being* a pericardial effusion.

DOID_11502
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: mitral valve improper close during left ventricular systole
  intersection of: Restriction
    on property: BFO_0000113
    some values from: mitral valve disorder
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: retrograd blood flow through mitral valve during left ventricular systole
CVDO definition: A disease in which an abnormal structure in a mitral valve prevents it to close propertly during systole, occasioning a retrograd blood flow through the valve.

DOID_11563
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: inflammation process in a retinal artery
CVDO definition: A disease characterized by an inflammation of a retinal artery.

DOID_11695
type: Class
equivalent class: Class
  intersection of: thrombosis
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA_66645
CVDO definition: A thrombosis that occurs in a portal vein.

DOID_11840
type: Class
equivalent class: Class
  intersection of: DOID 3393
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: coronary artery smooth muscle constriction
CVDO definition: A coronary heart disease with coronary artery smooth muscle constriction.

DOID_11847
type: Class
equivalent class: Class
  intersection of: thrombosis
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA_49893
CVDO definition: A thrombosis occuring in a coronary artery.

DOID_11984
type: Class
subclass of: OGMS_0000031
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: left ventricular myocardium hypertrophy
    intersection of: Restriction
      on property: BFO_0000117
      some values from: left ventricular myocardium contraction dysfunctional process
CVDO definition: "A heart disease with increased ventricular wall thickness or mass in the absence of loading conditions (hypertension, valve disease) sufficient to cause the observed abnormality." (Elliott et al., 2008, European Heart Journal, 29, 270-276)

DOID_12326
type: Class
equivalent class: Class
  intersection of: DOID 8515
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000064
      intersection of: Restriction
        on property: BFO_0000117
        some values from: right ventricular myocardium hypertrophy
CVDO definition: A cor pulmonale that has a chronic disease course during which the right ventricle becomes hypertrophied.

DOID 1287
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Class
    union of: Restriction
      on property: BFO_0000054
      some values from: Class
        intersection of: OGMS_0000063
        intersection of: Restriction
    union of: Restriction
      on property: BFO_0000113
      some values from: cardiovascular system disorder
CVDO definition: A disease affecting the cardiovascular system.

DOID_12929
type: Class
subclass of: OGMS_0000031
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: endocardium thickening
CVDO definition: A heart disease in which the endocardium thickens by increase in the amount of supporting connective tissue and elastic fibers. It is usually associated with children two years old and younger. Its etiological cause is unknown.

DOID_12930
type: Class
subclass of: OGMS_0000031
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: left ventricular myocardium dilatation
    intersection of: Restriction
      on property: BFO_0000117
      some values from: left ventricular myocardium contraction dysfunctional process
CVDO definition: A cardiomyopathy characterized by left ventricular dilatation and left ventricular systolic dysfunction in the absence of abnormal loading conditions (hypertension, valve disease) or coronary heart disease sufficient to cause global systolic impairment. (adapted from Elliott et al., 2008, European Heart Journal, 29, 270-276)

DOID_12935
type: Class
subclass of: DOID_12930
CVDO definition: A dilated cardiomyopathy resulting from alcohol intoxication.

DOID_13884
type: Class
subclass of: DOID_10273
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Class
      union of: Restriction
        on property: BFO_0000117
        some values from: sinoatrial arrest (process)
      union of: Restriction
        on property: BFO_0000117
        some values from: sinus bradycardia (process)
subclass of: Restriction
  on property: BFO_0000113
  some values from: impaired sinus node
CVDO definition: A heart conduction disease characterized by inappropriate sinus rates (e.g. sinus bradycardia or sinus pause).

DOID_14265
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: pulmonary valve improper close during right ventricular diastole
  intersection of: Restriction
    on property: BFO_0000113
    some values from: pulmonary valve disorder
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: retrograd blood flow through pulmonary valve during right ventricular diastole
CVDO definition: A disease in which an abnormal structure in a pulmonary valve prevents it to close propertly during diastole, occasioning a retrograd blood flow through the valve.

DOID 1461
type: Class
subclass of: embolism
CVDO definition: An embolism due to an embolus made of cholesterol.

DOID 1712
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: aortic valve improper opening during left ventricular systole
  intersection of: Restriction
    on property: BFO_0000113
    some values from: aortic valve disorder
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: disturbed anterograd blood flow through aortic valve during left ventricular systole
CVDO definition: A disease in which some disorder of the aortic valve leads prevents it from opening properly during left ventricular systole, occasioning disturbance in the anterograd blood flow through the valve.

DOID 1754
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: mitral valve narrowed opening during left ventricular diastole
  intersection of: Restriction
    on property: BFO_0000113
    some values from: mitral valve disorder
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: disturbed anterograd blood flow through mitral valve during left ventricular diastole
CVDO definition: A disease in which some disorder of a mitral valve prevents it from opening properly during left ventricular diastole, occasioning disturbance in the anterograd blood flow through the valve.

DOID 178
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Class
    union of: Restriction
      on property: BFO_0000054
      some values from: Class
        intersection of: OGMS_0000063
        intersection of: Restriction
    union of: Restriction
      on property: BFO_0000113
      some values from: vascular disorder
CVDO definition: A disease affecting a blood vessel.
CVDO editor note: Reorganization of the vascular diseases, and writing of Aristotelian definitions, is still ongoing.

DOID 1787
type: Class
subclass of: OGMS_0000031
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: inflammation process in a pericardium
CVDO definition: A disease characterized by an inflammation of the pericardium.

DOID 1869
type: Class
subclass of: Class
  intersection of: DOID 1787
  intersection of: Restriction
    on property: BFO_0000054
    some values from: OGMS_0000064
CVDO definition: A chronic pericarditis due to rheumatic fever.

DOID 1929
type: Class
subclass of: congenital disease
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: disturbed anterograd blood flow through aortic valve during left ventricular systole
    intersection of: Restriction
      on property: BFO_0000117
      some values from: aortic valve improper opening during left ventricular systole
    intersection of: Restriction
      on property: BFO_0000117
      some values from: aorta pathological process
CVDO definition: A congenital disease involving the narrowing (stenosis) of aorta, hindering the opening of the aortic valve.
CVDO editor note: Supravalvular aortic stenosis is not classified as an aortic valve stenosis: although the narrowing of the section of the aorta at the exit of the aortic valve implies some improper opening of the aortic valve, the aortic valve is (in general) healthy (there is no disorder nor pathological process inside it). However, this improper opening of the aortic valve is a pathological process that happens inside the heart; therefore, supravalvular aortic stenosis is classified as a heart disease.

DOID 224
type: Class
equivalent class: Class
  intersection of: DOID 2316
  intersection of: Restriction
    on property: BFO_0000132
    some values from: OGMS_0000066
CVDO definition: A brain ischemia that is part of a transient disease course.

DOID 2316
CVDO definition: An ischemia of the brain.

DOID 2403
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000113
    some values from: aneurysm (disorder)
CVDO definition: A disposition that an aneurysm disorder will lead to pathological processes.
CVDO editor note: DOID label 'aneurysm disease' changed for homogeneization purpose in CVDO.

DOID 326
type: Class
subclass of: OGMS_0000061
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA 3710
CVDO definition: A pathological process of restriction in blood supply to tissues, causing a shortage of oxygen and glucose needed for cellular metabolism.

DOID 3393
type: Class
subclass of: DOID 3394
CVDO definition: An ischemic heart disease with narrowing of the coronary arteries.

DOID 3394
type: Class
subclass of: OGMS_0000031
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: heart pathological process
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: heart ischemia
CVDO definition: A disease characterized by reduced blood supply to the heart, occasioning pathological processes in the heart.

DOID 3410
type: Class
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA 3939
CVDO definition: A thrombosis occurring in a carotid artery.

DOID 3454
type: Class
equivalent class: Class
  intersection of: infarction
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA_50801
comment: An infarction occurring in the brain.

DOID 3455
type: Class
subclass of: OGMS_0000061
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA_45840
CVDO definition: A pathological process of disturbance in the blood supply to the brain, causing a loss of brain function.

DOID 3572
type: Class
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA_50762
CVDO definition: A thrombosis that occurs in a dural venous sinus.

DOID 3574
type: Class
subclass of: DOID 3572
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA_50763
CVDO definition: A thrombosis that occurs in a transverse sinus.

DOID 3951
type: Class
equivalent class: Class
  intersection of: DOID 820
  intersection of: Restriction
    on property: BFO_0000054
    some values from: OGMS_0000094
CVDO definition: A myocarditis with an acute disease course.

DOID 397
type: Class
subclass of: OGMS_0000031
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000065
    intersection of: Restriction
      on property: BFO_0000117
      some values from: left ventricular myocardium contraction dysfunctional process
    intersection of: Restriction
      on property: BFO_0000117
      some values from: myocardium of left ventricle stiffening
CVDO definition: A cardiomyopathy (2008) characterized by increased stiffness of the left ventricular myocardium and decreased compliance of the left ventricle (which is restricted from stretching and filling with blood properly), in the absence of dilated cardiomyopathy and hypertrophic cardiomyopathy.

DOID 4078
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: tricuspid valve narrowed opening during right ventricular diastole
  intersection of: Restriction
    on property: BFO_0000113
    some values from: tricuspid valve disorder
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: disturbed anterograd blood flow through tricuspid valve during right ventricular diastole
CVDO definition: A disease in which some disorder of a tricuspid valve prevents it from opening properly during right ventricular diastole, occasioning disturbance in the anterograd blood flow through the valve.

DOID 4079
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Class
    union of: Restriction
      on property: BFO_0000054
      some values from: Class
        intersection of: OGMS_0000063
        intersection of: Restriction
    union of: Restriction
      on property: BFO_0000113
      some values from: heart valve disorder
CVDO definition: A disease affecting a valve of the heart.

DOID 4080
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: tricuspid valve improper close during right ventricular systole
  intersection of: Restriction
    on property: BFO_0000113
    some values from: tricuspid valve disorder
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: retrograd blood flow through tricuspid valve during right ventricular systole
CVDO definition: A disease in which an abnormal structure in a mitral valve prevents it to close propertly during systole, occasioning a retrograd blood flow through the valve.

DOID 4193
type: Class
subclass of: thrombosis
subclass of: Restriction
  on property: BFO_0000066
  some values from: FMA_50801
CVDO definition: A thrombosis occurring in the brain.

DOID 4248
type: Class
subclass of: OGMS_0000045
subclass of: Restriction
  on property: BFO_0000082
  some values from: FMA_49893
CVDO definition: A disorder of atheromous plaques in a coronary artery.

DOID 4562
type: Class
subclass of: bacterial endocarditis
CVDO definition: A bacterial endocarditis characterized by a slow process of infection.

DOID 519
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: inflammation process in aorta
CVDO definition: A disease characterized by an inflammation of the aorta.

DOID 520
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Class
    union of: Restriction
      on property: BFO_0000054
      some values from: Class
        intersection of: OGMS_0000063
        intersection of: Restriction
    union of: Restriction
      on property: BFO_0000113
      some values from: aorta disorder
CVDO definition: A disease affecting the aorta.

DOID 5232
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: aortic valve leaflet displacement into the left ventricle during left ventricular diastole
  intersection of: Restriction
    on property: BFO_0000113
    some values from: degenerated structure in an aortic valve leaflet
CVDO definition: A disease characterized by the displacement of a degenerated aortic valve leaflet into the left ventricle during diastole.

DOID 5644
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: tricuspid valve leaflet displacement into the right atrium during right ventricular systole
  intersection of: Restriction
    on property: BFO_0000113
    some values from: degenerated structure in a tricuspid valve leaflet
CVDO definition: A disease characterized by the displacement of a degenerated tricuspid valve leaflet into the right atrium during systole.

DOID 57
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: aortic valve improper close during left ventricular diastole
  intersection of: Restriction
    on property: BFO_0000113
    some values from: aortic valve disorder
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: retrograd blood flow through aortic valve during left ventricular diastole
CVDO definition: A disease in which an abnormal structure in an aortic valve prevents it to close propertly during diastole, occasioning a retrograd blood flow through the valve.

DOID 5749
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Class
    union of: Restriction
      on property: BFO_0000054
      some values from: Class
        intersection of: OGMS_0000063
        intersection of: Restriction
    union of: Restriction
      on property: BFO_0000113
      some values from: pulmonary valve disorder
CVDO definition: A disease affecting the pulmonary valve of the heart.

DOID 5805
type: Class
subclass of: OGMS_0000031
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: disturbed anterograd blood flow through aortic valve during left ventricular systole
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: aortic valve improper opening during left ventricular systole
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: left ventricle pathological process
CVDO editor note: This refers to a narrowing of the section of the left ventricle below the aortic valve; therefore, this was not classified as an aortic valve stenosis in CVDO.

DOID 5844
type: Class
equivalent class: Class
  intersection of: infarction
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA 9462
subclass of: Restriction
  on property: BFO_0000132
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000055
      some values from: DOID 8805
CVDO definition: An infarction occurring in the myocardium.

DOID 6000
type: Class
subclass of: OGMS_0000031
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: impaired cardiac output
disjoint union of: DOID 9651
disjoint union of: DOID 9775
CVDO definition: A disease characterized by the inability of the heart to pump a sufficient amount of blood throughout the body.

DOID 61
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Class
    union of: Restriction
      on property: BFO_0000054
      some values from: Class
        intersection of: OGMS_0000063
        intersection of: Restriction
    union of: Restriction
      on property: BFO_0000113
      some values from: mitral valve disorder
CVDO definition: A disease affecting the mitral valve of the heart.

DOID 62
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Class
    union of: Restriction
      on property: BFO_0000054
      some values from: Class
        intersection of: OGMS_0000063
        intersection of: Restriction
    union of: Restriction
      on property: BFO_0000113
      some values from: aortic valve disorder
CVDO definition: A disease affecting the aortic valve of the heart.

DOID 6420
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: pulmonary valve narrowed opening during right ventricular systole
  intersection of: Restriction
    on property: BFO_0000113
    some values from: pulmonary valve disorder
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: disturbed anterograd blood flow through pulmonary valve during right ventricular systole
CVDO definition: A disease in which some disorder of a pulmonary valve prevents it from opening properly during right ventricular systole, occasioning disturbance in the anterograd blood flow through the valve.

DOID 820
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: inflammation process in a myocardium
CVDO definition: A disease characterized by an inflammation of the myocardium.

DOID 8514
type: Class
equivalent class: DOID 8517
equivalent class: Class
  intersection of: DOID 8515
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000094
      intersection of: Restriction
        on property: BFO_0000117
        some values from: right ventricular myocardium dilatation
CVDO definition: A cor pulmonale that has an acute disease course during which the right ventricle becomes dilated.
CVDO editor note: 'Acute pulmonary heart disease' and 'Acute cor pulmonale' (two classes imported from DOID) are considered as equivalent in CVDO.

DOID 8515
type: Class
subclass of: OGMS_0000031
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Class
      union of: Restriction
        on property: BFO_0000117
        some values from: right ventricular myocardium dilatation
      union of: Restriction
        on property: BFO_0000117
        some values from: right ventricular myocardium hypertrophy
    intersection of: Restriction
      on property: BFO_0000117
      some values from: right ventricular myocardium contraction dysfunctional process
disjoint union of: DOID_12326
disjoint union of: DOID 8514
CVDO definition: A disease characterized by a dilatation or hypertrophy of the myocardium of right ventricle of the heart as a response to increased resistance or high blood pressure in the lungs, involving a failure of the right side of the heart.
CVDO editor note: Although the 1995 classification of cardiomyopathies did not include cor pulmonale, it should have included it, given the definition of cardiomyopathy it adopted.

DOID 8516
type: Class
subclass of: OGMS_0000061
subclass of: Restriction
  on property: BFO_0000117
  some values from: infarction
subclass of: Restriction
  on property: BFO_0000117
  some values from: DOID 9477
CVDO definition: A pathological process consisting in a pulmonary embolism and an infarction that follows.

DOID 8517
type: Class
equivalent class: Class
  intersection of: DOID 8515
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000094
      intersection of: Restriction
        on property: BFO_0000117
        some values from: right ventricular myocardium dilatation
CVDO editor note: 'Acute pulmonary heart disease' and 'Acute cor pulmonale' (two classes imported from DOID) are considered as equivalent in CVDO.

DOID 864
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: inflammation process in a vein
CVDO definition: A disease characterized by an inflammation of a vein.

DOID 865
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: inflammation process in a blood vessel
CVDO definition: A disease characterized by an inflammation of a blood vessel.

DOID 8805
type: Class
subclass of: DOID 3393
subclass of: Restriction
  on property: BFO_0000054
  some values from: OGMS_0000094
CVDO definition: A coronary heart disease with an acute disease course.
CVDO editor note: DOID label 'intermediate coronary syndrome' was changed.

DOID 8861
type: Class
subclass of: OGMS_0000031
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: disturbed anterograd blood flow through pulmonary valve during right ventricular systole
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: pulmonary valve narrowed opening during right ventricular systole
subclass of: Restriction
  on property: BFO_0000054
  some values from: Class
    intersection of: OGMS_0000063
    intersection of: Restriction
      on property: BFO_0000117
      some values from: right ventricle pathological process
CVDO editor note: DOID label 'pulmonary subvalvular stenosis' was changed for homogeneization with 'subvalvular aortic stenosis'.
has exact synonym: pulmonary subvalvular stenosis

DOID 9477
type: Class
equivalent class: Class
  intersection of: embolism
  intersection of: Restriction
    on property: BFO_0000066
    some values from: FMA_66326
CVDO definition: An embolism that occurs in a pulmonary artery.

DOID 9651
CVDO definition: A congestive heart failure with impaired ejection fraction.

DOID 9775
CVDO definition: A congestive heart failure with preserved ejection fraction.

DOID 988
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: mitral valve leaflet displacement into the left atrium during left ventricular systole
  intersection of: Restriction
    on property: BFO_0000113
    some values from: degenerated structure in a mitral valve leaflet
CVDO definition: A disease characterized by the displacement of a degenerated mitral valve leaflet into the left atrium during systole.

DOID 989
type: Class
equivalent class: Class
  intersection of: OGMS_0000031
  intersection of: Restriction
    on property: BFO_0000054
    some values from: Class
      intersection of: OGMS_0000063
      intersection of: Restriction
        on property: BFO_0000117
        some values from: heart valve leaflet displacement into a cardiac chamber
  intersection of: Restriction
    on property: BFO_0000113
    some values from: degenerated structure in a heart valve leaflet
CVDO definition: A disease characterized by the displacement of a degenerated heart valve leaflet during systole.

FMA_67165
type: Class
subclass of: BFO_0000040
CVDO editor note: This class was relocated as a son of BFO 'Material entity', and BFO 2.0 'located in at all times' relations were added between relevant FMA classes; they should ultimately be replaced by a genuine version of FMA using BFO 2.0 relations.

OGMS_0000031
type: Class
subclass of: BFO_0000016
CVDO definition: In order to obtain the taxonomy of diseases / disorders / pathological process in CVDO, it is necessary to use the reasoner first and to look at the inferred class hierarchy.

intracranial aneurysm disease

ruptured thoracoabdominal aortic aneurysm disease

DOID_12325
CVDO definition: A chronic pulmonary heart disease caused by a kyphoscoliosis.

DOID_12932
CVDO definition: A restrictive cardiomyopathy which results in fibrous lesions of right and left ventricle. It occurs typically in tropical and subtropical Africa.

thoracic aortic aneurysm disease

splenic artery aneurysm disease

DOID_14172
CVDO definition: A congestive heart failure caused by a rheumatic fever.

DOID 324
CVDO definition: An ischemia occurring in the spinal cord.

coronary aneurysm disease

subclavian artery aneurysm disease

DOID 3575
CVDO definition: A thrombosis that occurs in a cavernous sinus.

aortic aneurysm disease

DOID 55
CVDO definition: An aortic valve insufficiency due to rheumatic fever.

ruptured aortic aneurysm disease

dissecting aortic aneurysm disease

ruptured abdominal aortic aneurysm disease

abdominal aortic aneurysm disease

ruptured thoracic aortic aneurysm disease

DOID 8481
CVDO definition: A myocarditis caused by rheumatic fever.

DOID 9997
CVDO definition: A dilated cardiomyopathy resulting from a pregnancy. It presents typically between the last month of pregnancy and up to six months postpartum.

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