Cardio Vascular Disease Ontology
type: Ontology
version IRI: cvdo.owl
creator: Adrien Barton
creator: Arnaud Rosier
creator: Jean-François Ethier
creator: Paul Fabry
license: http://creativecommons.org/licenses/by/4.0/
comment: CVDO is an ontology of cardiovascular diseases structured on OBO foundry’s principle and based on BFO. CVDO reorganizes and completes DOID cardiovascular diseases following OGMS tripartite model of disease, and builds its taxonomy of diseases largely by automatic reasoning.
version info: 2024-05-17

BFO OWL specification label
type: AnnotationProperty
definition: Relates an entity in the ontology to the name of the variable that is used to represent it in the code that generates the BFO OWL file from the lispy specification.
curator note: Really of interest to developers only
sub property of: label

BFO CLIF specification label
type: AnnotationProperty
definition: Relates an entity in the ontology to the term that is used to represent it in the the CLIF specification of BFO2
definition source: Person:Alan Ruttenberg
curator note: Really of interest to developers only
sub property of: label

CVDO definition
type: AnnotationProperty
CVDO editor note: This annotation property is created temporarily for better visibility of the distinction between DOID definitions and updated CVDO definition (when a DOID definition of a class did not need to be changed, no additional CVDO definition was included). Ultimately, 'CVDO definition' annotation properties should be replaced by 'definition' annotation properties.
sub property of: definition

CVDO editor note
type: AnnotationProperty
comment: This annotation property is created temporarily for better visibility of the CVDO notes, in particular those that concern DOID classes. Ultimately, 'CVDO editor note' annotation properties should be replaced by 'editor note' annotation properties, or removed.
sub property of: editor note

editor preferred term
type: AnnotationProperty
editor preferred term: editor preferred term
has curation status: ready for release
definition: The concise, meaningful, and human-friendly name for a class or property preferred by the ontology developers. (US-English)
definition editor: PERSON:Daniel Schober
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>

example of usage
type: AnnotationProperty

has curation status
type: AnnotationProperty
editor preferred term: has curation status
definition editor: PERSON:Alan Ruttenberg
definition editor: PERSON:Bill Bug
definition editor: PERSON:Melanie Courtot
definition source: OBI_0000281

definition
type: AnnotationProperty
editor preferred term: definition
has curation status: ready for release
definition: The official definition, explaining the meaning of a class or property. Shall be Aristotelian, formalized and normalized. Can be augmented with colloquial definitions.
definition editor: PERSON:Daniel Schober
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>

editor note
type: AnnotationProperty
editor preferred term: editor note
has curation status: ready for release
definition: An administrative note intended for its editor. It may not be included in the publication version of the ontology, so it should contain nothing necessary for end users to understand the ontology.
definition editor: PERSON:Daniel Schober
definition source: GROUP:OBI:<http://purl.obfoundry.org/obo/obi>

definition editor
type: AnnotationProperty
editor preferred term: definition editor
has curation status: ready for release
definition: Name of editor entering the definition in the file. The definition editor is a point of contact for information regarding the term. The definition editor may be, but is not always, the author of the definition, which may have been worked upon by several people
definition editor: PERSON:Daniel Schober
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
label: term editor

alternative term
type: AnnotationProperty

definition source
type: AnnotationProperty
editor preferred term: definition source
has curation status: ready for release
definition: formal citation, e.g. identifier in external database to indicate / attribute source(s) for the definition. Free text indicate / attribute source(s) for the definition. EXAMPLE: Author Name, URI, MeSH Term C04, PUBMED ID, Wiki uri on 31.01.2007
definition editor: PERSON:Daniel Schober
definition source: GROUP:OBI:<http://purl.obolibrary.org/obo/obi>
definition source: Discussion on obo-discuss mailing-list, see http://bit.ly/hgm99w

curator note
type: AnnotationProperty
editor preferred term: curator note
has curation status: ready for release
definition: An administrative note of use for a curator but of no use for a user
definition editor: PERSON:Alan Ruttenberg

imported from
type: AnnotationProperty

elucidation
type: AnnotationProperty

has associated axiom(nl)
type: AnnotationProperty

has associated axiom(fol)
type: AnnotationProperty

has axiom label
type: AnnotationProperty

gram-positive bacterial infectious disease
type: AnnotationProperty
comment: gram-positive bacterial infectious disease
sub property of: subset_property

subset_property
type: AnnotationProperty

has_alternative_id
type: AnnotationProperty

database_cross_reference
type: AnnotationProperty

has_exact_synonym
type: AnnotationProperty

has_obo_namespace
type: AnnotationProperty

has_related_synonym
type: AnnotationProperty

in_subset
type: AnnotationProperty

inheres in at all times
type: ObjectProperty
sub property of: specifically depends on at all times
domain: specifically dependent continuant
range: Class
BFO OWL specification label: inheres-in_at
BFO CLIF specification label: inheresInAt
definition: b inheres_in c at t =Def. b is a dependent continuant & c is an independent continuant that is not a spatial region & b s-depends_on c at t. (axiom label in BFO2 Reference: [051-002])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'inheres in at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'inheres in@en(x,y,t)'.
editor note: BFO 2 Reference: Inherence is a subrelation of s-depends_on which holds between a dependent continuant and an independent continuant that is not a spatial region. Since dependent continuants cannot migrate from one independent continuant bearer to another, it follows that if b s-depends_on independent continuant c at some time, then b s-depends_on c at all times at which a exists. Inherence is in this sense redundantly time-indexed.For example, consider the particular instance of openness inhering in my mouth at t as I prepare to take a bite out of a donut, followed by a closedness at t+1 when I bite the donut and start chewing. The openness instance is then shortlived, and to say that it s-depends_on my mouth at all times at which this openness exists, means: at all times during this short life. Every time you make a fist, you make a new (instance of the universal) fist. (Every time your hand has the fist-shaped quality, there is created a new instance of the universal fist-shaped quality.)
editor note: BFO2 Reference: independent continuant that is not a spatial region
editor note: BFO2 Reference: specifically dependent continuant
has associated axiom(fol): (iff (inheresInAt a b t) (and (DependentContinuant a) (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))) // axiom label in BFO2 CLIF: [051-002]

Axiom
annotated source: inheres in at all times
annotated property: definition
annotated target: b inheres_in c at t =Def. b is a dependent continuant & c is an independent continuant that is not a spatial region & b s-depends_on c at t. (axiom label in BFO2 Reference: [051-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/051-002

Axiom
annotated source: inheres in at all times
annotated property: has associated axiom(fol)
annotated target: (iff (inheresInAt a b t) (and (DependentContinuant a) (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))) // axiom label in BFO2 CLIF: [051-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/051-002

bearer of at some time
type: ObjectProperty
sub property of: has specific dependent at some time
domain: Class
range: specifically dependent continuant
BFO OWL specification label: bearer-of_st
BFO CLIF specification label: bearerOfAt
definition: b bearer_of c at t =Def. c s-depends_on b at t & b is an independent continuant that is not a spatial region. (axiom label in BFO2 Reference: [053-004])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'bearer of at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'bearer of@en'(x,y,t)
editor note: BFO2 Reference: independent continuant that is not a spatial region
editor note: BFO2 Reference: specifically dependent continuant
has associated axiom(fol): (iff (bearerOfAt a b t) (and (specificallyDependsOnAt b a t) (IndependentContinuant a) (not (SpatialRegion a)) (existsAt b t))) // axiom label in BFO2 CLIF: [053-004]

Axiom
annotated source: bearer of at some time
annotated property: definition
annotated target: b bearer_of c at t =Def. c s-depends_on b at t & b is an independent continuant that is not a spatial region. (axiom label in BFO2 Reference: [053-004])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/053-004

Axiom
annotated source: bearer of at some time
annotated property: has associated axiom(fol)
annotated target: (iff (bearerOfAt a b t) (and (specificallyDependsOnAt b a t) (IndependentContinuant a) (not (SpatialRegion a)) (existsAt b t))) // axiom label in BFO2 CLIF: [053-004]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/053-004

realized in
type: ObjectProperty
inverse of: realizes
domain: realizable entity
range: process
BFO OWL specification label: realized-in
BFO CLIF specification label: realizedIn
elucidation: [copied from inverse property 'realizes'] to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])
has associated axiom(nl): if a realizable entity b is realized in a process p, then p stands in the has_participant relation to the bearer of b. (axiom label in BFO2 Reference: [106-002])
has associated axiom(fol): (forall (x y z t) (if (and (RealizableEntity x) (Process y) (realizesAt y x t) (bearerOfAt z x t)) (hasParticipantAt y z t))) // axiom label in BFO2 CLIF: [106-002]

Axiom
annotated source: realized in
annotated property: has associated axiom(nl)
annotated target: if a realizable entity b is realized in a process p, then p stands in the has_participant relation to the bearer of b. (axiom label in BFO2 Reference: [106-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/106-002

Axiom
annotated source: realized in
annotated property: has associated axiom(fol)
annotated target: (forall (x y z t) (if (and (RealizableEntity x) (Process y) (realizesAt y x t) (bearerOfAt z x t)) (hasParticipantAt y z t))) // axiom label in BFO2 CLIF: [106-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/106-002

realizes
type: ObjectProperty
domain: process
range: realizable entity
BFO OWL specification label: realizes
BFO CLIF specification label: realizes
elucidation: to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])
has associated axiom(fol): (forall (x y t) (if (realizesAt x y t) (and (Process x) (or (Disposition y) (Role y)) (exists (z) (and (MaterialEntity z) (hasParticipantAt x z t) (bearerOfAt z y t)))))) // axiom label in BFO2 CLIF: [059-003]

Axiom
annotated source: realizes
annotated property: elucidation
annotated target: to say that b realizes c at t is to assert that there is some material entity d & b is a process which has participant d at t & c is a disposition or role of which d is bearer_of at t& the type instantiated by b is correlated with the type instantiated by c. (axiom label in BFO2 Reference: [059-003])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/059-003

Axiom
annotated source: realizes
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (realizesAt x y t) (and (Process x) (or (Disposition y) (Role y)) (exists (z) (and (MaterialEntity z) (hasParticipantAt x z t) (bearerOfAt z y t)))))) // axiom label in BFO2 CLIF: [059-003]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/059-003

participates in at some time
type: ObjectProperty
inverse of: has participant at some time
domain: Class
range: process
BFO OWL specification label: participates-in_st
BFO CLIF specification label: participatesInAt
editor note: [copied from inverse property 'has participant at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has participant at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has participant@en'(x,y,t)
editor note: [copied from inverse property 'has participant at some time'] BFO 2 Reference: Spatial regions do not participate in processes.
editor note: [copied from inverse property 'has participant at some time'] BFO2 Reference: independent continuant that is not a spatial region, specifically dependent continuant, generically dependent continuant
editor note: [copied from inverse property 'has participant at some time'] BFO2 Reference: process
elucidation: [copied from inverse property 'has participant at some time'] has_participant is an instance-level relation between a process, a continuant, and a temporal region at which the continuant participates in some way in the process. (axiom label in BFO2 Reference: [086-003])

has participant at some time
type: ObjectProperty
domain: process
range: Class
property chain axiom: realizes
property chain axiom: inheres in at all times
BFO OWL specification label: has-participant_st
BFO CLIF specification label: hasParticipantAt
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has participant at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has participant@en'(x,y,t)
editor note: BFO 2 Reference: Spatial regions do not participate in processes.
editor note: BFO2 Reference: independent continuant that is not a spatial region, specifically dependent continuant, generically dependent continuant
editor note: BFO2 Reference: process
elucidation: has_participant is an instance-level relation between a process, a continuant, and a temporal region at which the continuant participates in some way in the process. (axiom label in BFO2 Reference: [086-003])
has associated axiom(nl): if b has_participant c at t & c is a generically dependent continuant, then there is some independent continuant that is not a spatial region d, and which is such that c g-depends on d at t & b s-depends_on d at t. (axiom label in BFO2 Reference: [091-003])
has associated axiom(nl): if b has_participant c at t & c is a specifically dependent continuant, then there is some independent continuant that is not a spatial region d, c s-depends_on d at t & b s-depends_on d at t. (axiom label in BFO2 Reference: [090-003])
has associated axiom(nl): if b has_participant c at t then b is an occurrent. (axiom label in BFO2 Reference: [087-001])
has associated axiom(nl): if b has_participant c at t then c exists at t. (axiom label in BFO2 Reference: [089-001])
has associated axiom(nl): if b has_participant c at t then c is a continuant. (axiom label in BFO2 Reference: [088-001])
has associated axiom(fol): (forall (x y t) (if (and (hasParticipantAt x y t) (GenericallyDependentContinuant y)) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (genericallyDependsOn y z t) (specificallyDependsOnAt x z t))))) // axiom label in BFO2 CLIF: [091-003]
has associated axiom(fol): (forall (x y t) (if (and (hasParticipantAt x y t) (SpecificallyDependentContinuant y)) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (specificallyDependsOnAt x z t) (specificallyDependsOnAt y z t))))) // axiom label in BFO2 CLIF: [090-003]
has associated axiom(fol): (forall (x y t) (if (hasParticipantAt x y t) (Continuant y))) // axiom label in BFO2 CLIF: [088-001]
has associated axiom(fol): (forall (x y t) (if (hasParticipantAt x y t) (Occurrent x))) // axiom label in BFO2 CLIF: [087-001]
has associated axiom(fol): (forall (x y t) (if (hasParticipantAt x y t) (existsAt y t))) // axiom label in BFO2 CLIF: [089-001]

Axiom
annotated source: has participant at some time
annotated property: elucidation
annotated target: has_participant is an instance-level relation between a process, a continuant, and a temporal region at which the continuant participates in some way in the process. (axiom label in BFO2 Reference: [086-003])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/086-003

Axiom
annotated source: has participant at some time
annotated property: has associated axiom(nl)
annotated target: if b has_participant c at t & c is a generically dependent continuant, then there is some independent continuant that is not a spatial region d, and which is such that c g-depends on d at t & b s-depends_on d at t. (axiom label in BFO2 Reference: [091-003])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/091-003

Axiom
annotated source: has participant at some time
annotated property: has associated axiom(nl)
annotated target: if b has_participant c at t & c is a specifically dependent continuant, then there is some independent continuant that is not a spatial region d, c s-depends_on d at t & b s-depends_on d at t. (axiom label in BFO2 Reference: [090-003])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/090-003

Axiom
annotated source: has participant at some time
annotated property: has associated axiom(nl)
annotated target: if b has_participant c at t then b is an occurrent. (axiom label in BFO2 Reference: [087-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/087-001

Axiom
annotated source: has participant at some time
annotated property: has associated axiom(nl)
annotated target: if b has_participant c at t then c exists at t. (axiom label in BFO2 Reference: [089-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/089-001

Axiom
annotated source: has participant at some time
annotated property: has associated axiom(nl)
annotated target: if b has_participant c at t then c is a continuant. (axiom label in BFO2 Reference: [088-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/088-001

Axiom
annotated source: has participant at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (and (hasParticipantAt x y t) (GenericallyDependentContinuant y)) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (genericallyDependsOn y z t) (specificallyDependsOnAt x z t))))) // axiom label in BFO2 CLIF: [091-003]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/091-003

Axiom
annotated source: has participant at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (and (hasParticipantAt x y t) (SpecificallyDependentContinuant y)) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (specificallyDependsOnAt x z t) (specificallyDependsOnAt y z t))))) // axiom label in BFO2 CLIF: [090-003]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/090-003

Axiom
annotated source: has participant at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (hasParticipantAt x y t) (Continuant y))) // axiom label in BFO2 CLIF: [088-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/088-001

Axiom
annotated source: has participant at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (hasParticipantAt x y t) (Occurrent x))) // axiom label in BFO2 CLIF: [087-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/087-001

Axiom
annotated source: has participant at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (hasParticipantAt x y t) (existsAt y t))) // axiom label in BFO2 CLIF: [089-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/089-001

concretized by at some time
type: ObjectProperty
inverse of: concretizes at some time
domain: generically dependent continuant
range: specifically dependent continuant
BFO OWL specification label: concretized-by_st
example of usage: [copied from inverse property 'concretizes at some time'] You may concretize a piece of software by installing it in your computer
example of usage: [copied from inverse property 'concretizes at some time'] You may concretize a recipe that you find in a cookbook by turning it into a plan which exists as a realizable dependent continuant in your head.
example of usage: [copied from inverse property 'concretizes at some time'] you may concretize a poem as a pattern of memory traces in your head
editor note: [copied from inverse property 'concretizes at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'concretizes at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'concretizes@en'(x,y,t)
elucidation: [copied from inverse property 'concretizes at some time'] b concretizes c at t means: b is a specifically dependent continuant & c is a generically dependent continuant & for some independent continuant that is not a spatial region d, b s-depends_on d at t & c g-depends on d at t & if c migrates from bearer d to another bearer e than a copy of b will be created in e. (axiom label in BFO2 Reference: [075-002])

concretizes at some time
type: ObjectProperty
domain: specifically dependent continuant
range: generically dependent continuant
BFO OWL specification label: concretizes_st
BFO CLIF specification label: concretizesAt
example of usage: You may concretize a piece of software by installing it in your computer
example of usage: You may concretize a recipe that you find in a cookbook by turning it into a plan which exists as a realizable dependent continuant in your head.
example of usage: you may concretize a poem as a pattern of memory traces in your head
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'concretizes at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'concretizes@en'(x,y,t)
elucidation: b concretizes c at t means: b is a specifically dependent continuant & c is a generically dependent continuant & for some independent continuant that is not a spatial region d, b s-depends_on d at t & c g-depends on d at t & if c migrates from bearer d to another bearer e than a copy of b will be created in e. (axiom label in BFO2 Reference: [075-002])
has associated axiom(nl): if b g-depends on c at some time t, then there is some d, such that d concretizes b at t and d s-depends_on c at t. (axiom label in BFO2 Reference: [076-001])
has associated axiom(fol): (forall (x y t) (if (concretizesAt x y t) (and (SpecificallyDependentContinuant x) (GenericallyDependentContinuant y) (exists (z) (and (IndependentContinuant z) (specificallyDependsOnAt x z t) (genericallyDependsOnAt y z t)))))) // axiom label in BFO2 CLIF: [075-002]
has associated axiom(fol): (forall (x y t) (if (genericallyDependsOnAt x y t) (exists (z) (and (concretizesAt z x t) (specificallyDependsOnAt z y t))))) // axiom label in BFO2 CLIF: [076-001]

Axiom
annotated source: concretizes at some time
annotated property: elucidation
annotated target: b concretizes c at t means: b is a specifically dependent continuant & c is a generically dependent continuant & for some independent continuant that is not a spatial region d, b s-depends_on d at t & c g-depends on d at t & if c migrates from bearer d to another bearer e than a copy of b will be created in e. (axiom label in BFO2 Reference: [075-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/075-002

Axiom
annotated source: concretizes at some time
annotated property: has associated axiom(nl)
annotated target: if b g-depends on c at some time t, then there is some d, such that d concretizes b at t and d s-depends_on c at t. (axiom label in BFO2 Reference: [076-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/076-001

Axiom
annotated source: concretizes at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (concretizesAt x y t) (and (SpecificallyDependentContinuant x) (GenericallyDependentContinuant y) (exists (z) (and (IndependentContinuant z) (specificallyDependsOnAt x z t) (genericallyDependsOnAt y z t)))))) // axiom label in BFO2 CLIF: [075-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/075-002

Axiom
annotated source: concretizes at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (genericallyDependsOnAt x y t) (exists (z) (and (concretizesAt z x t) (specificallyDependsOnAt z y t))))) // axiom label in BFO2 CLIF: [076-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/076-001

occurs in
type: ObjectProperty
inverse of: contains process
domain: Class
range: Class
property chain axiom: located in at all times
BFO OWL specification label: occurs-in
BFO CLIF specification label: occursIn
CVDO editor note: CVDO adds the property chain that if A occurs_in B and B located_in_at_all_times C, then A occurs_in C. This is used for a few inferences in the ontology, but CVDO can be used without problem without this property chain.
definition: b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t [XXX-001

contains process
type: ObjectProperty
domain: Class
range: Class
BFO OWL specification label: contains-process
BFO CLIF specification label: containsProcess
definition: [copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t [XXX-001

specifically depends on at all times
type: ObjectProperty
sub property of: specifically depends on at some time
BFO OWL specification label: s-depends-on_at
BFO CLIF specification label: specificallyDependsOn
example of usage: A pain s-depends_on the organism that is experiencing the pain
example of usage: a gait s-depends_on the walking object. (All at some specific time.)
example of usage: a shape s-depends_on the shaped object
example of usage: one-sided s-dependence of a dependent continuant on an independent continuant: an instance of headache s-depends_on some head
example of usage: one-sided s-dependence of a dependent continuant on an independent continuant: an instance of temperature s-depends_on some organism
example of usage: one-sided s-dependence of a process on something: a process of cell death s-depends_on a cell
example of usage: one-sided s-dependence of a process on something: an instance of seeing (a relational process) s-depends_on some organism and on some seen entity, which may be an occurrent or a continuant
example of usage: one-sided s-dependence of one occurrent on another: a process of answering a question is dependent on a prior process of asking a question
example of usage: one-sided s-dependence of one occurrent on another: a process of obeying a command is dependent on a prior process of issuing a command
example of usage: one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of hitting a ball with a cricket bat
example of usage: one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of paying cash to a merchant in exchange for a bag of figs
example of usage: reciprocal s-dependence between occurrents: a process of buying and the associated process of selling
example of usage: reciprocal s-dependence between occurrents: a process of increasing the volume of a portion of gas while temperature remains constant and the associated process of decreasing the pressure exerted by the gas
example of usage: reciprocal s-dependence between occurrents: in a game of chess the process of playing with the white pieces is mutually dependent on the process of playing with the black pieces
example of usage: the one-sided dependence of an occurrent on an independent continuant: football match on the players, the ground, the ball
example of usage: the one-sided dependence of an occurrent on an independent continuant: handwave on a hand
example of usage: the three-sided reciprocal s-dependence of the hue, saturation and brightness of a color [45
example of usage: the three-sided reciprocal s-dependence of the pitch, timbre and volume of a tone [45
example of usage: the two-sided reciprocal s-dependence of the roles of husband and wife [20
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'specifically depends on at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'specifically depends on@en(x,y,t)'.
editor note: BFO 2 Reference: An entity – for example an act of communication or a game of football – can s-depends_on more than one entity. Complex phenomena for example in the psychological and social realms (such as inferring, commanding and requesting) or in the realm of multi-organismal biological processes (such as infection and resistance), will involve multiple families of dependence relations, involving both continuants and occurrents [1, 4, 28
editor note: BFO 2 Reference: S-dependence is just one type of dependence among many; it is what, in the literature, is referred to as ‘existential dependence’ [87, 46, 65, 20
editor note: BFO 2 Reference: the relation of s-depends_on does not in every case require simultaneous existence of its relata. Note the difference between such cases and the cases of continuant universals defined historically: the act of answering depends existentially on the prior act of questioning; the human being who was baptized or who answered a question does not himself depend existentially on the prior act of baptism or answering. He would still exist even if these acts had never taken place.
editor note: BFO2 Reference: specifically dependent continuant\; process; process boundary
elucidation: To say that b s-depends_on a at t is to say that b and c do not share common parts & b is of its nature such that it cannot exist unless c exists & b is not a boundary of c and b is not a site of which c is the host [64
has associated axiom(nl): If b is s-depends_on something at some time, then b is not a material entity. (axiom label in BFO2 Reference: [052-001])
has associated axiom(nl): If b s-depends_on something at t, then there is some c, which is an independent continuant and not a spatial region, such that b s-depends_on c at t. (axiom label in BFO2 Reference: [136-001])
has associated axiom(nl): If occurrent b s-depends_on some independent continuant c at t, then b s-depends_on c at every time at which b exists. (axiom label in BFO2 Reference: [015-002])
has associated axiom(nl): an entity does not s-depend_on any of its (continuant or occurrent) parts or on anything it is part of. (axiom label in BFO2 Reference: [013-002])
has associated axiom(nl): if b s-depends_on c at t & c s-depends_on d at t then b s-depends_on d at t. (axiom label in BFO2 Reference: [054-002])
has associated axiom(fol): (forall (x y t) (if (and (Entity x) (or (continuantPartOfAt y x t) (continuantPartOfAt x y t) (occurrentPartOf x y) (occurrentPartOf y x))) (not (specificallyDependsOnAt x y t)))) // axiom label in BFO2 CLIF: [013-002]
has associated axiom(fol): (forall (x y t) (if (and (Occurrent x) (IndependentContinuant y) (specificallyDependsOnAt x y t)) (forall (t_1) (if (existsAt x t_1) (specificallyDependsOnAt x y t_1))))) // axiom label in BFO2 CLIF: [015-002]
has associated axiom(fol): (forall (x y t) (if (specificallyDependsOnAt x y t) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (specificallyDependsOnAt x z t))))) // axiom label in BFO2 CLIF: [136-001]
has associated axiom(fol): (forall (x y z t) (if (and (specificallyDependsOnAt x y t) (specificallyDependsOnAt y z t)) (specificallyDependsOnAt x z t))) // axiom label in BFO2 CLIF: [054-002]
has associated axiom(fol): (forall (x) (if (exists (y t) (specificallyDependsOnAt x y t)) (not (MaterialEntity x)))) // axiom label in BFO2 CLIF: [052-001]

Axiom
annotated source: specifically depends on at all times
annotated property: has associated axiom(nl)
annotated target: If b is s-depends_on something at some time, then b is not a material entity. (axiom label in BFO2 Reference: [052-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/052-001

Axiom
annotated source: specifically depends on at all times
annotated property: has associated axiom(nl)
annotated target: If b s-depends_on something at t, then there is some c, which is an independent continuant and not a spatial region, such that b s-depends_on c at t. (axiom label in BFO2 Reference: [136-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/136-001

Axiom
annotated source: specifically depends on at all times
annotated property: has associated axiom(nl)
annotated target: If occurrent b s-depends_on some independent continuant c at t, then b s-depends_on c at every time at which b exists. (axiom label in BFO2 Reference: [015-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/015-002

Axiom
annotated source: specifically depends on at all times
annotated property: has associated axiom(nl)
annotated target: an entity does not s-depend_on any of its (continuant or occurrent) parts or on anything it is part of. (axiom label in BFO2 Reference: [013-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/013-002

Axiom
annotated source: specifically depends on at all times
annotated property: has associated axiom(nl)
annotated target: if b s-depends_on c at t & c s-depends_on d at t then b s-depends_on d at t. (axiom label in BFO2 Reference: [054-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/054-002

Axiom
annotated source: specifically depends on at all times
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (and (Entity x) (or (continuantPartOfAt y x t) (continuantPartOfAt x y t) (occurrentPartOf x y) (occurrentPartOf y x))) (not (specificallyDependsOnAt x y t)))) // axiom label in BFO2 CLIF: [013-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/013-002

Axiom
annotated source: specifically depends on at all times
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (and (Occurrent x) (IndependentContinuant y) (specificallyDependsOnAt x y t)) (forall (t_1) (if (existsAt x t_1) (specificallyDependsOnAt x y t_1))))) // axiom label in BFO2 CLIF: [015-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/015-002

Axiom
annotated source: specifically depends on at all times
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (specificallyDependsOnAt x y t) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (specificallyDependsOnAt x z t))))) // axiom label in BFO2 CLIF: [136-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/136-001

Axiom
annotated source: specifically depends on at all times
annotated property: has associated axiom(fol)
annotated target: (forall (x y z t) (if (and (specificallyDependsOnAt x y t) (specificallyDependsOnAt y z t)) (specificallyDependsOnAt x z t))) // axiom label in BFO2 CLIF: [054-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/054-002

Axiom
annotated source: specifically depends on at all times
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (exists (y t) (specificallyDependsOnAt x y t)) (not (MaterialEntity x)))) // axiom label in BFO2 CLIF: [052-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/052-001

function of at all times
type: ObjectProperty
sub property of: inheres in at all times
domain: function
BFO OWL specification label: f-of_at
BFO CLIF specification label: functionOfAt
definition: a function_of b at t =Def. a is a function and a inheres_in b at t. (axiom label in BFO2 Reference: [067-001])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'function of at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'function of@en(x,y,t)'.
has associated axiom(fol): (iff (functionOf a b t) (and (Function a) (inheresInAt a b t))) // axiom label in BFO2 CLIF: [067-001]

Axiom
annotated source: function of at all times
annotated property: definition
annotated target: a function_of b at t =Def. a is a function and a inheres_in b at t. (axiom label in BFO2 Reference: [067-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/067-001

Axiom
annotated source: function of at all times
annotated property: has associated axiom(fol)
annotated target: (iff (functionOf a b t) (and (Function a) (inheresInAt a b t))) // axiom label in BFO2 CLIF: [067-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/067-001

quality of at all times
type: ObjectProperty
sub property of: inheres in at all times
domain: quality
BFO OWL specification label: q-of_at
BFO CLIF specification label: qualityOfAt
definition: b quality_of c at t = Def. b is a quality & c is an independent continuant that is not a spatial region & b s-depends_on c at t. (axiom label in BFO2 Reference: [056-002])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'quality of at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'quality of@en(x,y,t)'.
has associated axiom(fol): (iff (qualityOfAt a b t) (and (Quality a) (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))) // axiom label in BFO2 CLIF: [056-002]

Axiom
annotated source: quality of at all times
annotated property: definition
annotated target: b quality_of c at t = Def. b is a quality & c is an independent continuant that is not a spatial region & b s-depends_on c at t. (axiom label in BFO2 Reference: [056-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/056-002

Axiom
annotated source: quality of at all times
annotated property: has associated axiom(fol)
annotated target: (iff (qualityOfAt a b t) (and (Quality a) (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))) // axiom label in BFO2 CLIF: [056-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/056-002

role of at all times
type: ObjectProperty
sub property of: inheres in at all times
domain: role
BFO OWL specification label: r-of_at
BFO CLIF specification label: roleOfAt
definition: a role_of b at t =Def. a is a role and a inheres_in b at t. (axiom label in BFO2 Reference: [065-001])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'role of at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'role of@en(x,y,t)'.
has associated axiom(fol): (iff (roleOfAt a b t) (and (Role a) (inheresInAt a b t))) // axiom label in BFO2 CLIF: [065-001]

Axiom
annotated source: role of at all times
annotated property: definition
annotated target: a role_of b at t =Def. a is a role and a inheres_in b at t. (axiom label in BFO2 Reference: [065-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/065-001

Axiom
annotated source: role of at all times
annotated property: has associated axiom(fol)
annotated target: (iff (roleOfAt a b t) (and (Role a) (inheresInAt a b t))) // axiom label in BFO2 CLIF: [065-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/065-001

located in at all times
type: ObjectProperty
sub property of: located in at some time
type: TransitiveProperty
BFO OWL specification label: located-in_at
BFO CLIF specification label: locatedInAt
example of usage: Mary located_in Salzburg
example of usage: the Empire State Building located_in New York.
example of usage: this portion of cocaine located_in this portion of blood
example of usage: this stem cell located_in this portion of bone marrow
example of usage: your arm located_in your body
definition: b located_in c at t = Def. b and c are independent continuants, and the region at which b is located at t is a (proper or improper) continuant_part_of the region at which c is located at t. (axiom label in BFO2 Reference: [045-001])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'located in at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'located in@en(x,y,t)'.
editor note: BFO2 Reference: independent continuant
has associated axiom(nl): Located_in is transitive. (axiom label in BFO2 Reference: [046-001])
has associated axiom(nl): for all independent continuants b, c, and d: if b continuant_part_of c at t & c located_in d at t, then b located_in d at t. (axiom label in BFO2 Reference: [048-001])
has associated axiom(nl): for all independent continuants b, c, and d: if b located_in c at t & c continuant_part_of d at t, then b located_in d at t. (axiom label in BFO2 Reference: [049-001])
has associated axiom(fol): (forall (x y z t) (if (and (IndependentContinuant x) (IndependentContinuant y) (IndependentContinuant z) (continuantPartOfAt x y t) (locatedInAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [048-001]
has associated axiom(fol): (forall (x y z t) (if (and (IndependentContinuant x) (IndependentContinuant y) (IndependentContinuant z) (locatedInAt x y t) (continuantPartOfAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [049-001]
has associated axiom(fol): (forall (x y z t) (if (and (locatedInAt x y t) (locatedInAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [046-001]
has associated axiom(fol): (iff (locatedInAt a b t) (and (IndependentContinuant a) (IndependentContinuant b) (exists (r_1 r_2) (and (occupiesSpatialRegionAt a r_1 t) (occupiesSpatialRegionAt b r_2 t) (continuantPartOfAt r_1 r_2 t))))) // axiom label in BFO2 CLIF: [045-001]

Axiom
annotated source: located in at all times
annotated property: has associated axiom(fol)
annotated target: (forall (x y z t) (if (and (IndependentContinuant x) (IndependentContinuant y) (IndependentContinuant z) (continuantPartOfAt x y t) (locatedInAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [048-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/048-001

Axiom
annotated source: located in at all times
annotated property: has associated axiom(fol)
annotated target: (forall (x y z t) (if (and (IndependentContinuant x) (IndependentContinuant y) (IndependentContinuant z) (locatedInAt x y t) (continuantPartOfAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [049-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/049-001

Axiom
annotated source: located in at all times
annotated property: has associated axiom(fol)
annotated target: (forall (x y z t) (if (and (locatedInAt x y t) (locatedInAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [046-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/046-001

Axiom
annotated source: located in at all times
annotated property: has associated axiom(fol)
annotated target: (iff (locatedInAt a b t) (and (IndependentContinuant a) (IndependentContinuant b) (exists (r_1 r_2) (and (occupiesSpatialRegionAt a r_1 t) (occupiesSpatialRegionAt b r_2 t) (continuantPartOfAt r_1 r_2 t))))) // axiom label in BFO2 CLIF: [045-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/045-001

Axiom
annotated source: located in at all times
annotated property: definition
annotated target: b located_in c at t = Def. b and c are independent continuants, and the region at which b is located at t is a (proper or improper) continuant_part_of the region at which c is located at t. (axiom label in BFO2 Reference: [045-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/045-001

Axiom
annotated source: located in at all times
annotated property: has associated axiom(nl)
annotated target: Located_in is transitive. (axiom label in BFO2 Reference: [046-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/046-001

Axiom
annotated source: located in at all times
annotated property: has associated axiom(nl)
annotated target: for all independent continuants b, c, and d: if b continuant_part_of c at t & c located_in d at t, then b located_in d at t. (axiom label in BFO2 Reference: [048-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/048-001

Axiom
annotated source: located in at all times
annotated property: has associated axiom(nl)
annotated target: for all independent continuants b, c, and d: if b located_in c at t & c continuant_part_of d at t, then b located_in d at t. (axiom label in BFO2 Reference: [049-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/049-001

occupies spatial region at some time
type: ObjectProperty
inverse of: has spatial occupant at some time
domain: independent continuant
range: spatial region
BFO OWL specification label: located-at-r_st
BFO CLIF specification label: occupiesSpatialRegionAt
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'occupies spatial region at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'occupies spatial region@en'(x,y,t)
editor note: BFO2 Reference: independent continuant
editor note: BFO2 Reference: spatial region
elucidation: b occupies_spatial_region r at t means that r is a spatial region in which independent continuant b is exactly located (axiom label in BFO2 Reference: [041-002])
has associated axiom(nl): every region r is occupies_spatial_region r at all times. (axiom label in BFO2 Reference: [042-002])
has associated axiom(nl): if b occupies_spatial_region r at t & b continuant_part_of b at t, then there is some r which is continuant_part_of r at t such that b occupies_spatial_region r at t. (axiom label in BFO2 Reference: [043-001])
has associated axiom(fol): (forall (r t) (if (Region r) (occupiesSpatialRegionAt r r t))) // axiom label in BFO2 CLIF: [042-002]
has associated axiom(fol): (forall (x r t) (if (occupiesSpatialRegionAt x r t) (and (SpatialRegion r) (IndependentContinuant x)))) // axiom label in BFO2 CLIF: [041-002]
has associated axiom(fol): (forall (x y r_1 t) (if (and (occupiesSpatialRegionAt x r_1 t) (continuantPartOfAt y x t)) (exists (r_2) (and (continuantPartOfAt r_2 r_1 t) (occupiesSpatialRegionAt y r_2 t))))) // axiom label in BFO2 CLIF: [043-001]

Axiom
annotated source: occupies spatial region at some time
annotated property: elucidation
annotated target: b occupies_spatial_region r at t means that r is a spatial region in which independent continuant b is exactly located (axiom label in BFO2 Reference: [041-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/041-002

Axiom
annotated source: occupies spatial region at some time
annotated property: has associated axiom(nl)
annotated target: every region r is occupies_spatial_region r at all times. (axiom label in BFO2 Reference: [042-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/042-002

Axiom
annotated source: occupies spatial region at some time
annotated property: has associated axiom(nl)
annotated target: if b occupies_spatial_region r at t & b continuant_part_of b at t, then there is some r which is continuant_part_of r at t such that b occupies_spatial_region r at t. (axiom label in BFO2 Reference: [043-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/043-001

Axiom
annotated source: occupies spatial region at some time
annotated property: has associated axiom(fol)
annotated target: (forall (r t) (if (Region r) (occupiesSpatialRegionAt r r t))) // axiom label in BFO2 CLIF: [042-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/042-002

Axiom
annotated source: occupies spatial region at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x r t) (if (occupiesSpatialRegionAt x r t) (and (SpatialRegion r) (IndependentContinuant x)))) // axiom label in BFO2 CLIF: [041-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/041-002

Axiom
annotated source: occupies spatial region at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x y r_1 t) (if (and (occupiesSpatialRegionAt x r_1 t) (continuantPartOfAt y x t)) (exists (r_2) (and (continuantPartOfAt r_2 r_1 t) (occupiesSpatialRegionAt y r_2 t))))) // axiom label in BFO2 CLIF: [043-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/043-001

generically depends on at some time
type: ObjectProperty
inverse of: has generic dependent at some time
domain: generically dependent continuant
range: Class
BFO OWL specification label: g-depends-on_st
BFO CLIF specification label: genericallyDependsOn
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'generically depends on at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'generically depends on@en'(x,y,t)
editor note: BFO2 Reference: generically dependent continuant
editor note: BFO2 Reference: independent continuant
elucidation: b g-depends on c at t1 means: b exists at t1 and c exists at t1 & for some type B it holds that (c instantiates B at t1) & necessarily, for all t (if b exists at t then some instance_of B exists at t) & not (b s-depends_on c at t1). (axiom label in BFO2 Reference: [072-002])
has associated axiom(nl): if b g-depends_on c at some time t, then b g-depends_on something at all times at which b exists. (axiom label in BFO2 Reference: [073-001])
has associated axiom(fol): (forall (x y) (if (exists (t) (genericallyDependsOnAt x y t)) (forall (t_1) (if (existsAt x t_1) (exists (z) (genericallyDependsOnAt x z t_1)))))) // axiom label in BFO2 CLIF: [073-001]

Axiom
annotated source: generically depends on at some time
annotated property: elucidation
annotated target: b g-depends on c at t1 means: b exists at t1 and c exists at t1 & for some type B it holds that (c instantiates B at t1) & necessarily, for all t (if b exists at t then some instance_of B exists at t) & not (b s-depends_on c at t1). (axiom label in BFO2 Reference: [072-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/072-002

Axiom
annotated source: generically depends on at some time
annotated property: has associated axiom(nl)
annotated target: if b g-depends_on c at some time t, then b g-depends_on something at all times at which b exists. (axiom label in BFO2 Reference: [073-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/073-001

Axiom
annotated source: generically depends on at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x y) (if (exists (t) (genericallyDependsOnAt x y t)) (forall (t_1) (if (existsAt x t_1) (exists (z) (genericallyDependsOnAt x z t_1)))))) // axiom label in BFO2 CLIF: [073-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/073-001

has function at some time
type: ObjectProperty
sub property of: bearer of at some time
range: function
BFO OWL specification label: has-f_st
BFO CLIF specification label: hasFunctionAt
definition: a has_function b at t =Def. b function_of a at t. (axiom label in BFO2 Reference: [070-001])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has function at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has function@en'(x,y,t)
has associated axiom(fol): (iff (hasFunctionAt a b t) (functionOf b a t)) // axiom label in BFO2 CLIF: [070-001]

Axiom
annotated source: has function at some time
annotated property: definition
annotated target: a has_function b at t =Def. b function_of a at t. (axiom label in BFO2 Reference: [070-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/070-001

Axiom
annotated source: has function at some time
annotated property: has associated axiom(fol)
annotated target: (iff (hasFunctionAt a b t) (functionOf b a t)) // axiom label in BFO2 CLIF: [070-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/070-001

has quality at some time
type: ObjectProperty
sub property of: bearer of at some time
range: quality
BFO OWL specification label: has-q_st

has role at some time
type: ObjectProperty
sub property of: bearer of at some time
range: role
BFO OWL specification label: has-r_st
BFO CLIF specification label: hasRoleAt
definition: a has_role b at t =Def. b role_of a at t. (axiom label in BFO2 Reference: [068-001])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has role at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has role@en'(x,y,t)
has associated axiom(fol): (iff (hasRoleAt a b t) (roleOfAt b a t)) // axiom label in BFO2 CLIF: [068-001]

Axiom
annotated source: has role at some time
annotated property: definition
annotated target: a has_role b at t =Def. b role_of a at t. (axiom label in BFO2 Reference: [068-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/068-001

Axiom
annotated source: has role at some time
annotated property: has associated axiom(fol)
annotated target: (iff (hasRoleAt a b t) (roleOfAt b a t)) // axiom label in BFO2 CLIF: [068-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/068-001

has generic dependent at some time
type: ObjectProperty
domain: Class
range: generically dependent continuant
property chain axiom: has specific dependent at some time
property chain axiom: concretizes at all times
BFO OWL specification label: has-g-dep_st
editor note: [copied from inverse property 'generically depends on at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'generically depends on at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'generically depends on@en'(x,y,t)
editor note: [copied from inverse property 'generically depends on at some time'] BFO2 Reference: generically dependent continuant
editor note: [copied from inverse property 'generically depends on at some time'] BFO2 Reference: independent continuant
elucidation: [copied from inverse property 'generically depends on at some time'] b g-depends on c at t1 means: b exists at t1 and c exists at t1 & for some type B it holds that (c instantiates B at t1) & necessarily, for all t (if b exists at t then some instance_of B exists at t) & not (b s-depends_on c at t1). (axiom label in BFO2 Reference: [072-002])

disposition of at all times
type: ObjectProperty
sub property of: inheres in at all times
domain: disposition
BFO OWL specification label: d-of_at
BFO CLIF specification label: dispositionOfAt
definition: a disposition_of b at t =Def. a is a disposition and a inheres_in b at t. (axiom label in BFO2 Reference: [066-001])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'disposition of at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'disposition of@en(x,y,t)'.
has associated axiom(fol): (iff (dispositionOf a b t) (and (Disposition a) (inheresInAt a b t))) // axiom label in BFO2 CLIF: [066-001]

Axiom
annotated source: disposition of at all times
annotated property: definition
annotated target: a disposition_of b at t =Def. a is a disposition and a inheres_in b at t. (axiom label in BFO2 Reference: [066-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/066-001

Axiom
annotated source: disposition of at all times
annotated property: has associated axiom(fol)
annotated target: (iff (dispositionOf a b t) (and (Disposition a) (inheresInAt a b t))) // axiom label in BFO2 CLIF: [066-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/066-001

exists at
type: ObjectProperty
inverse of: during which exists
domain: entity
range: temporal region
BFO OWL specification label: exists-at
BFO CLIF specification label: existsAt
editor note: BFO2 Reference: entity
editor note: BFO2 Reference: temporal region
elucidation: b exists_at t means: b is an entity which exists at some temporal region t. (axiom label in BFO2 Reference: [118-002])

Axiom
annotated source: exists at
annotated property: elucidation
annotated target: b exists_at t means: b is an entity which exists at some temporal region t. (axiom label in BFO2 Reference: [118-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/118-002

has continuant part at all times
type: ObjectProperty
sub property of: has continuant part at some time
inverse of: part of continuant at all times that whole exists
type: TransitiveProperty
BFO OWL specification label: c-has-part_at
BFO CLIF specification label: hasContinuantPartAt
definition: [copied from inverse property 'part of continuant at all times that whole exists'] forall(t) exists_at(y,t) -> exists_at(x,t) and 'part of continuant'(x,y,t)
definition: b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'has continuant part at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'has continuant part@en(x,y,t)'.
editor note: [copied from inverse property 'part of continuant at all times that whole exists'] This is a binary version of a ternary time-indexed, instance level, relation. Unlike the rest of the temporalized relations which temporally quantify over existence of the subject of the relation, this relation temporally quantifies over the existence of the object of the relation. The relation is provided tentatively, to assess whether the GO needs such a relation. It is inverse of 'has continuant part at all times'
has associated axiom(fol): (iff (hasContinuantPartAt a b t) (continuantPartOfAt b a t)) // axiom label in BFO2 CLIF: [006-001]

Axiom
annotated source: has continuant part at all times
annotated property: definition
annotated target: b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/006-001

Axiom
annotated source: has continuant part at all times
annotated property: has associated axiom(fol)
annotated target: (iff (hasContinuantPartAt a b t) (continuantPartOfAt b a t)) // axiom label in BFO2 CLIF: [006-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/006-001

has proper continuant part at all times
type: ObjectProperty
sub property of: has continuant part at all times
sub property of: has proper continuant part at some time
type: TransitiveProperty
BFO OWL specification label: c-has-ppart_at
BFO CLIF specification label: hasProperContinuantPartAt
definition: b has_proper_continuant_part c at t = Def. c proper_continuant_part_of b at t. [XXX-001
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'has proper continuant part at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'has proper continuant part@en(x,y,t)'.

has disposition at some time
type: ObjectProperty
sub property of: bearer of at some time
range: disposition
BFO OWL specification label: has-d_st
BFO CLIF specification label: hasDispositionAt
definition: a has_disposition b at t =Def. b disposition_of a at t. (axiom label in BFO2 Reference: [069-001])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has disposition at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has disposition@en'(x,y,t)
has associated axiom(fol): (iff (hasDispositionAt a b t) (dispositionOf b a t)) // axiom label in BFO2 CLIF: [069-001]

Axiom
annotated source: has disposition at some time
annotated property: definition
annotated target: a has_disposition b at t =Def. b disposition_of a at t. (axiom label in BFO2 Reference: [069-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/069-001

Axiom
annotated source: has disposition at some time
annotated property: has associated axiom(fol)
annotated target: (iff (hasDispositionAt a b t) (dispositionOf b a t)) // axiom label in BFO2 CLIF: [069-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/069-001

has material basis at all times
type: ObjectProperty
domain: disposition
range: material entity
BFO OWL specification label: has-material-basis_at
BFO CLIF specification label: hasMaterialBasisAt
example of usage: the material basis of John’s disposition to cough is the viral infection in John’s upper respiratory tract
example of usage: the material basis of the disposition to wear unevenly of John’s tires is the worn suspension of his car.
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'has material basis at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'has material basis@en(x,y,t)'.
elucidation: b has_material_basis c at t means: b is a disposition & c is a material entity & there is some d bearer_of b at t& c continuant_part_of d at t& d has_disposition b at t because c continuant_part_of d at t. (axiom label in BFO2 Reference: [071-002])
has associated axiom(fol): (forall (x y t) (if (hasMaterialBasisAt x y t) (and (Disposition x) (MaterialEntity y) (exists (z) (and (bearerOfAt z x t) (continuantPartOfAt y z t) (exists (w) (and (Disposition w) (if (hasDisposition z w) (continuantPartOfAt y z t))))))))) // axiom label in BFO2 CLIF: [071-002]

Axiom
annotated source: has material basis at all times
annotated property: elucidation
annotated target: b has_material_basis c at t means: b is a disposition & c is a material entity & there is some d bearer_of b at t& c continuant_part_of d at t& d has_disposition b at t because c continuant_part_of d at t. (axiom label in BFO2 Reference: [071-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/071-002

Axiom
annotated source: has material basis at all times
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (hasMaterialBasisAt x y t) (and (Disposition x) (MaterialEntity y) (exists (z) (and (bearerOfAt z x t) (continuantPartOfAt y z t) (exists (w) (and (Disposition w) (if (hasDisposition z w) (continuantPartOfAt y z t))))))))) // axiom label in BFO2 CLIF: [071-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/071-002

has member part at some time
type: ObjectProperty
sub property of: has continuant part at some time
inverse of: member part of at some time
domain: continuant
range: continuant
BFO OWL specification label: has-member-part_st
example of usage: [copied from inverse property 'member part of at some time'] each piece in a chess set is a member part of the chess set; each Beatle in the collection called The Beatles is a member part of The Beatles.
example of usage: [copied from inverse property 'member part of at some time'] each tree in a forest is a member_part of the forest
definition: [copied from inverse property 'member part of at some time'] b member_part_of c at t =Def. b is an object & there is at t a mutually exhaustive and pairwise disjoint partition of c into objects x1, …, xn (for some n > 1) with b = xi for some 1 ? i ? n. (axiom label in BFO2 Reference: [026-004])
editor note: [copied from inverse property 'member part of at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'member part of at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'member part of@en'(x,y,t)
editor note: [copied from inverse property 'member part of at some time'] BFO2 Reference: object
editor note: [copied from inverse property 'member part of at some time'] BFO2 Reference: object aggregate

has occurrent part
type: ObjectProperty
inverse of: part of occurrent
type: TransitiveProperty
domain: occurrent
range: occurrent
BFO OWL specification label: o-has-part
BFO CLIF specification label: hasOccurrentPart
example of usage: [copied from inverse property 'part of occurrent'] Mary’s 5th birthday occurrent_part_of Mary’s life
example of usage: [copied from inverse property 'part of occurrent'] The process of a footballer’s heart beating once is an occurrent part but not a temporal_part of a game of football.
example of usage: [copied from inverse property 'part of occurrent'] the first set of the tennis match occurrent_part_of the tennis match.
definition: b has_occurrent_part c = Def. c occurrent_part_of b. (axiom label in BFO2 Reference: [007-001])
editor note: [copied from inverse property 'part of occurrent'] BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion.
editor note: [copied from inverse property 'part of occurrent'] BFO2 Reference: occurrent
elucidation: [copied from inverse property 'part of occurrent'] b occurrent_part_of c =Def. b is a part of c & b and c are occurrents. (axiom label in BFO2 Reference: [003-002])
has associated axiom(fol): (iff (hasOccurrentPart a b) (occurrentPartOf b a)) // axiom label in BFO2 CLIF: [007-001]

Axiom
annotated source: has occurrent part
annotated property: definition
annotated target: b has_occurrent_part c = Def. c occurrent_part_of b. (axiom label in BFO2 Reference: [007-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/007-001

Axiom
annotated source: has occurrent part
annotated property: has associated axiom(fol)
annotated target: (iff (hasOccurrentPart a b) (occurrentPartOf b a)) // axiom label in BFO2 CLIF: [007-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/007-001

has proper occurrent part
type: ObjectProperty
sub property of: has occurrent part
inverse of: proper part of occurrent
type: TransitiveProperty
domain: occurrent
range: occurrent
BFO OWL specification label: o-has-ppart
BFO CLIF specification label: hasProperOccurrentPart
definition: [copied from inverse property 'proper part of occurrent'] b proper_occurrent_part_of c =Def. b occurrent_part_of c & b and c are not identical. (axiom label in BFO2 Reference: [005-001])
definition: b has_proper_occurrent_part c = Def. c proper_occurrent_part_of b. [XXX-001

has profile
type: ObjectProperty
inverse of: process profile of
domain: process
range: process profile
BFO OWL specification label: has-profile

has temporal part
type: ObjectProperty
sub property of: has occurrent part
inverse of: temporal part of
type: TransitiveProperty
domain: occurrent
range: occurrent
BFO OWL specification label: has-t-part
example of usage: [copied from inverse property 'temporal part of'] the 4th year of your life is a temporal part of your life\. The first quarter of a game of football is a temporal part of the whole game\. The process of your heart beating from 4pm to 5pm today is a temporal part of the entire process of your heart beating.\ The 4th year of your life is a temporal part of your life
example of usage: [copied from inverse property 'temporal part of'] the process boundary which separates the 3rd and 4th years of your life.
example of usage: [copied from inverse property 'temporal part of'] your heart beating from 4pm to 5pm today is a temporal part of the process of your heart beating
definition: [copied from inverse property 'temporal part of'] b proper_temporal_part_of c =Def. b temporal_part_of c & not (b = c). (axiom label in BFO2 Reference: [116-001])
definition: [copied from inverse property 'temporal part of'] b temporal_part_of c =Def.b occurrent_part_of c & & for some temporal region t, b occupies_temporal_region t & for all occurrents d, t (if d occupies_temporal_region t & t? occurrent_part_of t then (d occurrent_part_of a iff d occurrent_part_of b)). (axiom label in BFO2 Reference: [078-003])

has spatial occupant at some time
type: ObjectProperty
domain: spatial region
range: independent continuant
BFO OWL specification label: r-location-of_st
editor note: [copied from inverse property 'occupies spatial region at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'occupies spatial region at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'occupies spatial region@en'(x,y,t)
editor note: [copied from inverse property 'occupies spatial region at some time'] BFO2 Reference: independent continuant
editor note: [copied from inverse property 'occupies spatial region at some time'] BFO2 Reference: spatial region
elucidation: [copied from inverse property 'occupies spatial region at some time'] b occupies_spatial_region r at t means that r is a spatial region in which independent continuant b is exactly located (axiom label in BFO2 Reference: [041-002])

has location at some time
type: ObjectProperty
inverse of: located in at some time
domain: independent continuant
range: independent continuant
BFO OWL specification label: has-location_st
example of usage: [copied from inverse property 'located in at some time'] Mary located_in Salzburg
example of usage: [copied from inverse property 'located in at some time'] the Empire State Building located_in New York.
example of usage: [copied from inverse property 'located in at some time'] this portion of cocaine located_in this portion of blood
example of usage: [copied from inverse property 'located in at some time'] this stem cell located_in this portion of bone marrow
example of usage: [copied from inverse property 'located in at some time'] your arm located_in your body
definition: [copied from inverse property 'located in at some time'] b located_in c at t = Def. b and c are independent continuants, and the region at which b is located at t is a (proper or improper) continuant_part_of the region at which c is located at t. (axiom label in BFO2 Reference: [045-001])
editor note: [copied from inverse property 'located in at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'located in at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'located in@en'(x,y,t)
editor note: [copied from inverse property 'located in at some time'] BFO2 Reference: independent continuant

has specific dependent at some time
type: ObjectProperty
inverse of: specifically depends on at some time
domain: Class
range: Class
BFO OWL specification label: has-s-dep_st
example of usage: [copied from inverse property 'specifically depends on at some time'] A pain s-depends_on the organism that is experiencing the pain
example of usage: [copied from inverse property 'specifically depends on at some time'] a gait s-depends_on the walking object. (All at some specific time.)
example of usage: [copied from inverse property 'specifically depends on at some time'] a shape s-depends_on the shaped object
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of a dependent continuant on an independent continuant: an instance of headache s-depends_on some head
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of a dependent continuant on an independent continuant: an instance of temperature s-depends_on some organism
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of a process on something: a process of cell death s-depends_on a cell
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of a process on something: an instance of seeing (a relational process) s-depends_on some organism and on some seen entity, which may be an occurrent or a continuant
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of one occurrent on another: a process of answering a question is dependent on a prior process of asking a question
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of one occurrent on another: a process of obeying a command is dependent on a prior process of issuing a command
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of hitting a ball with a cricket bat
example of usage: [copied from inverse property 'specifically depends on at some time'] one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of paying cash to a merchant in exchange for a bag of figs
example of usage: [copied from inverse property 'specifically depends on at some time'] reciprocal s-dependence between occurrents: a process of buying and the associated process of selling
example of usage: [copied from inverse property 'specifically depends on at some time'] reciprocal s-dependence between occurrents: a process of increasing the volume of a portion of gas while temperature remains constant and the associated process of decreasing the pressure exerted by the gas
example of usage: [copied from inverse property 'specifically depends on at some time'] reciprocal s-dependence between occurrents: in a game of chess the process of playing with the white pieces is mutually dependent on the process of playing with the black pieces
example of usage: [copied from inverse property 'specifically depends on at some time'] the one-sided dependence of an occurrent on an independent continuant: football match on the players, the ground, the ball
example of usage: [copied from inverse property 'specifically depends on at some time'] the one-sided dependence of an occurrent on an independent continuant: handwave on a hand
example of usage: [copied from inverse property 'specifically depends on at some time'] the three-sided reciprocal s-dependence of the hue, saturation and brightness of a color [45
example of usage: [copied from inverse property 'specifically depends on at some time'] the three-sided reciprocal s-dependence of the pitch, timbre and volume of a tone [45
example of usage: [copied from inverse property 'specifically depends on at some time'] the two-sided reciprocal s-dependence of the roles of husband and wife [20
editor note: [copied from inverse property 'specifically depends on at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'specifically depends on at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'specifically depends on@en'(x,y,t)
editor note: [copied from inverse property 'specifically depends on at some time'] BFO 2 Reference: An entity – for example an act of communication or a game of football – can s-depends_on more than one entity. Complex phenomena for example in the psychological and social realms (such as inferring, commanding and requesting) or in the realm of multi-organismal biological processes (such as infection and resistance), will involve multiple families of dependence relations, involving both continuants and occurrents [1, 4, 28
editor note: [copied from inverse property 'specifically depends on at some time'] BFO 2 Reference: S-dependence is just one type of dependence among many; it is what, in the literature, is referred to as ‘existential dependence’ [87, 46, 65, 20
editor note: [copied from inverse property 'specifically depends on at some time'] BFO 2 Reference: the relation of s-depends_on does not in every case require simultaneous existence of its relata. Note the difference between such cases and the cases of continuant universals defined historically: the act of answering depends existentially on the prior act of questioning; the human being who was baptized or who answered a question does not himself depend existentially on the prior act of baptism or answering. He would still exist even if these acts had never taken place.
editor note: [copied from inverse property 'specifically depends on at some time'] BFO2 Reference: specifically dependent continuant\; process; process boundary
elucidation: [copied from inverse property 'specifically depends on at some time'] To say that b s-depends_on a at t is to say that b and c do not share common parts & b is of its nature such that it cannot exist unless c exists & b is not a boundary of c and b is not a site of which c is the host [64

has spatiotemporal occupant
type: ObjectProperty
inverse of: occupies spatiotemporal region
domain: spatiotemporal region
range: occurrent
BFO OWL specification label: occupied-by
editor note: [copied from inverse property 'occupies spatiotemporal region'] BFO 2 Reference: The occupies_spatiotemporal_region and occupies_temporal_region relations are the counterpart, on the occurrent side, of the relation occupies_spatial_region.
elucidation: [copied from inverse property 'occupies spatiotemporal region'] p occupies_spatiotemporal_region s. This is a primitive relation between an occurrent p and the spatiotemporal region s which is its spatiotemporal extent. (axiom label in BFO2 Reference: [082-003])

material basis of at some time
type: ObjectProperty
domain: material entity
range: disposition
BFO OWL specification label: material-basis-of_st

member part of at some time
type: ObjectProperty
sub property of: proper part of continuant at some time
sub property of: part of continuant at some time
domain: continuant
range: continuant
BFO OWL specification label: member-part-of_st
BFO CLIF specification label: memberPartOfAt
example of usage: each piece in a chess set is a member part of the chess set; each Beatle in the collection called The Beatles is a member part of The Beatles.
example of usage: each tree in a forest is a member_part of the forest
definition: b member_part_of c at t =Def. b is an object & there is at t a mutually exhaustive and pairwise disjoint partition of c into objects x1, …, xn (for some n > 1) with b = xi for some 1 ? i ? n. (axiom label in BFO2 Reference: [026-004])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'member part of at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'member part of@en'(x,y,t)
editor note: BFO2 Reference: object
editor note: BFO2 Reference: object aggregate
has associated axiom(nl): if b member_part_of c at t then b continuant_part_of c at t. (axiom label in BFO2 Reference: [104-001])
has associated axiom(fol): (forall (x y t) (if (memberPartOfAt x y t) (continuantPartOfAt x y t))) // axiom label in BFO2 CLIF: [104-001]

Axiom
annotated source: member part of at some time
annotated property: definition
annotated target: b member_part_of c at t =Def. b is an object & there is at t a mutually exhaustive and pairwise disjoint partition of c into objects x1, …, xn (for some n > 1) with b = xi for some 1 ? i ? n. (axiom label in BFO2 Reference: [026-004])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/026-004

Axiom
annotated source: member part of at some time
annotated property: has associated axiom(nl)
annotated target: if b member_part_of c at t then b continuant_part_of c at t. (axiom label in BFO2 Reference: [104-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/104-001

Axiom
annotated source: member part of at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (memberPartOfAt x y t) (continuantPartOfAt x y t))) // axiom label in BFO2 CLIF: [104-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/104-001

occupies spatiotemporal region
type: ObjectProperty
domain: occurrent
range: spatiotemporal region
BFO OWL specification label: occupies
BFO CLIF specification label: occupiesSpatiotemporalRegion
editor note: BFO 2 Reference: The occupies_spatiotemporal_region and occupies_temporal_region relations are the counterpart, on the occurrent side, of the relation occupies_spatial_region.
elucidation: p occupies_spatiotemporal_region s. This is a primitive relation between an occurrent p and the spatiotemporal region s which is its spatiotemporal extent. (axiom label in BFO2 Reference: [082-003])

Axiom
annotated source: occupies spatiotemporal region
annotated property: elucidation
annotated target: p occupies_spatiotemporal_region s. This is a primitive relation between an occurrent p and the spatiotemporal region s which is its spatiotemporal extent. (axiom label in BFO2 Reference: [082-003])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/082-003

part of occurrent
type: ObjectProperty
type: TransitiveProperty
domain: occurrent
range: occurrent
BFO OWL specification label: o-part-of
BFO CLIF specification label: occurrentPartOf
example of usage: Mary’s 5th birthday occurrent_part_of Mary’s life
example of usage: The process of a footballer’s heart beating once is an occurrent part but not a temporal_part of a game of football.
example of usage: the first set of the tennis match occurrent_part_of the tennis match.
definition: [copied from inverse property 'has occurrent part'] b has_occurrent_part c = Def. c occurrent_part_of b. (axiom label in BFO2 Reference: [007-001])
editor note: BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion.
editor note: BFO2 Reference: occurrent
elucidation: b occurrent_part_of c =Def. b is a part of c & b and c are occurrents. (axiom label in BFO2 Reference: [003-002])
has associated axiom(nl): occurrent_part_of is antisymmetric. (axiom label in BFO2 Reference: [123-001])
has associated axiom(nl): occurrent_part_of is reflexive (every occurrent entity is an occurrent_part_of itself). (axiom label in BFO2 Reference: [113-002])
has associated axiom(nl): occurrent_part_of is transitive. (axiom label in BFO2 Reference: [112-001])
has associated axiom(nl): occurrent_part_of satisfies unique product. (axiom label in BFO2 Reference: [125-001])
has associated axiom(nl): occurrent_part_of satisfies weak supplementation. (axiom label in BFO2 Reference: [124-001])
has associated axiom(fol): (forall (x y t) (if (and (occurrentPartOf x y t) (not (= x y))) (exists (z) (and (occurrentPartOf z y t) (not (exists (w) (and (occurrentPartOf w x t) (occurrentPartOf w z t)))))))) // axiom label in BFO2 CLIF: [124-001]
has associated axiom(fol): (forall (x y t) (if (and (occurrentPartOf x y t) (occurrentPartOf y x t)) (= x y))) // axiom label in BFO2 CLIF: [123-001]
has associated axiom(fol): (forall (x y t) (if (exists (v) (and (occurrentPartOf v x t) (occurrentPartOf v y t))) (exists (z) (forall (u w) (iff (iff (occurrentPartOf w u t) (and (occurrentPartOf w x t) (occurrentPartOf w y t))) (= z u)))))) // axiom label in BFO2 CLIF: [125-001]
has associated axiom(fol): (forall (x y z) (if (and (occurrentPartOf x y) (occurrentPartOf y z)) (occurrentPartOf x z))) // axiom label in BFO2 CLIF: [112-001]
has associated axiom(fol): (forall (x) (if (Occurrent x) (occurrentPartOf x x))) // axiom label in BFO2 CLIF: [113-002]

Axiom
annotated source: part of occurrent
annotated property: elucidation
annotated target: b occurrent_part_of c =Def. b is a part of c & b and c are occurrents. (axiom label in BFO2 Reference: [003-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/003-002

Axiom
annotated source: part of occurrent
annotated property: has associated axiom(nl)
annotated target: occurrent_part_of is antisymmetric. (axiom label in BFO2 Reference: [123-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/123-001

Axiom
annotated source: part of occurrent
annotated property: has associated axiom(nl)
annotated target: occurrent_part_of is reflexive (every occurrent entity is an occurrent_part_of itself). (axiom label in BFO2 Reference: [113-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/113-002

Axiom
annotated source: part of occurrent
annotated property: has associated axiom(nl)
annotated target: occurrent_part_of is transitive. (axiom label in BFO2 Reference: [112-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/112-001

Axiom
annotated source: part of occurrent
annotated property: has associated axiom(nl)
annotated target: occurrent_part_of satisfies unique product. (axiom label in BFO2 Reference: [125-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/125-001

Axiom
annotated source: part of occurrent
annotated property: has associated axiom(nl)
annotated target: occurrent_part_of satisfies weak supplementation. (axiom label in BFO2 Reference: [124-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/124-001

Axiom
annotated source: part of occurrent
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (and (occurrentPartOf x y t) (not (= x y))) (exists (z) (and (occurrentPartOf z y t) (not (exists (w) (and (occurrentPartOf w x t) (occurrentPartOf w z t)))))))) // axiom label in BFO2 CLIF: [124-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/124-001

Axiom
annotated source: part of occurrent
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (and (occurrentPartOf x y t) (occurrentPartOf y x t)) (= x y))) // axiom label in BFO2 CLIF: [123-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/123-001

Axiom
annotated source: part of occurrent
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (exists (v) (and (occurrentPartOf v x t) (occurrentPartOf v y t))) (exists (z) (forall (u w) (iff (iff (occurrentPartOf w u t) (and (occurrentPartOf w x t) (occurrentPartOf w y t))) (= z u)))))) // axiom label in BFO2 CLIF: [125-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/125-001

Axiom
annotated source: part of occurrent
annotated property: has associated axiom(fol)
annotated target: (forall (x y z) (if (and (occurrentPartOf x y) (occurrentPartOf y z)) (occurrentPartOf x z))) // axiom label in BFO2 CLIF: [112-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/112-001

Axiom
annotated source: part of occurrent
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Occurrent x) (occurrentPartOf x x))) // axiom label in BFO2 CLIF: [113-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/113-002

process profile of
type: ObjectProperty
domain: process profile
range: process
BFO OWL specification label: profile-of
BFO CLIF specification label: processProfileOf

proper temporal part of
type: ObjectProperty
sub property of: proper part of occurrent
sub property of: temporal part of
inverse of: has proper temporal part
type: TransitiveProperty
domain: occurrent
range: occurrent
BFO OWL specification label: t-ppart-of
BFO CLIF specification label: properTemporalPartOf

proper part of continuant at all times
type: ObjectProperty
sub property of: proper part of continuant at some time
sub property of: part of continuant at all times
type: TransitiveProperty
BFO OWL specification label: c-ppart-of_at
BFO CLIF specification label: properContinuantPartOfAt
definition: b proper_continuant_part_of c at t =Def. b continuant_part_of c at t & b and c are not identical. (axiom label in BFO2 Reference: [004-001])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'proper part of continuant at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'proper part of continuant@en(x,y,t)'.
has associated axiom(fol): (iff (properContinuantPartOfAt a b t) (and (continuantPartOfAt a b t) (not (= a b)))) // axiom label in BFO2 CLIF: [004-001]

Axiom
annotated source: proper part of continuant at all times
annotated property: definition
annotated target: b proper_continuant_part_of c at t =Def. b continuant_part_of c at t & b and c are not identical. (axiom label in BFO2 Reference: [004-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/004-001

Axiom
annotated source: proper part of continuant at all times
annotated property: has associated axiom(fol)
annotated target: (iff (properContinuantPartOfAt a b t) (and (continuantPartOfAt a b t) (not (= a b)))) // axiom label in BFO2 CLIF: [004-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/004-001

proper part of occurrent
type: ObjectProperty
sub property of: part of occurrent
type: TransitiveProperty
domain: occurrent
range: occurrent
BFO OWL specification label: o-ppart-of
BFO CLIF specification label: properOccurrentPartOf
definition: [copied from inverse property 'has proper occurrent part'] b has_proper_occurrent_part c = Def. c proper_occurrent_part_of b. [XXX-001
definition: b proper_occurrent_part_of c =Def. b occurrent_part_of c & b and c are not identical. (axiom label in BFO2 Reference: [005-001])
has associated axiom(fol): (iff (properOccurrentPartOf a b) (and (occurrentPartOf a b) (not (= a b)))) // axiom label in BFO2 CLIF: [005-001]

Axiom
annotated source: proper part of occurrent
annotated property: definition
annotated target: b proper_occurrent_part_of c =Def. b occurrent_part_of c & b and c are not identical. (axiom label in BFO2 Reference: [005-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/005-001

Axiom
annotated source: proper part of occurrent
annotated property: has associated axiom(fol)
annotated target: (iff (properOccurrentPartOf a b) (and (occurrentPartOf a b) (not (= a b)))) // axiom label in BFO2 CLIF: [005-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/005-001

temporal part of
type: ObjectProperty
sub property of: part of occurrent
type: TransitiveProperty
domain: occurrent
range: occurrent
BFO OWL specification label: t-part-of
BFO CLIF specification label: temporalPartOf
example of usage: the 4th year of your life is a temporal part of your life\. The first quarter of a game of football is a temporal part of the whole game\. The process of your heart beating from 4pm to 5pm today is a temporal part of the entire process of your heart beating.\ The 4th year of your life is a temporal part of your life
example of usage: the process boundary which separates the 3rd and 4th years of your life.
example of usage: your heart beating from 4pm to 5pm today is a temporal part of the process of your heart beating
definition: b proper_temporal_part_of c =Def. b temporal_part_of c & not (b = c). (axiom label in BFO2 Reference: [116-001])
definition: b temporal_part_of c =Def.b occurrent_part_of c & & for some temporal region t, b occupies_temporal_region t & for all occurrents d, t (if d occupies_temporal_region t & t? occurrent_part_of t then (d occurrent_part_of a iff d occurrent_part_of b)). (axiom label in BFO2 Reference: [078-003])
has associated axiom(nl): if b proper_temporal_part_of c, then there is some d which is a proper_temporal_part_of c and which shares no parts with b. (axiom label in BFO2 Reference: [117-002])
has associated axiom(fol): (forall (x y) (if (properTemporalPartOf x y) (exists (z) (and (properTemporalPartOf z y) (not (exists (w) (and (temporalPartOf w x) (temporalPartOf w z)))))))) // axiom label in BFO2 CLIF: [117-002]
has associated axiom(fol): (iff (properTemporalPartOf a b) (and (temporalPartOf a b) (not (= a b)))) // axiom label in BFO2 CLIF: [116-001]
has associated axiom(fol): (iff (temporalPartOf a b) (and (occurrentPartOf a b) (exists (t) (and (TemporalRegion t) (occupiesSpatioTemporalRegion a t))) (forall (c t_1) (if (and (Occurrent c) (occupiesSpatioTemporalRegion c t_1) (occurrentPartOf t_1 r)) (iff (occurrentPartOf c a) (occurrentPartOf c b)))))) // axiom label in BFO2 CLIF: [078-003]

Axiom
annotated source: temporal part of
annotated property: definition
annotated target: b proper_temporal_part_of c =Def. b temporal_part_of c & not (b = c). (axiom label in BFO2 Reference: [116-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/116-001

Axiom
annotated source: temporal part of
annotated property: definition
annotated target: b temporal_part_of c =Def.b occurrent_part_of c & & for some temporal region t, b occupies_temporal_region t & for all occurrents d, t (if d occupies_temporal_region t & t? occurrent_part_of t then (d occurrent_part_of a iff d occurrent_part_of b)). (axiom label in BFO2 Reference: [078-003])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/078-003

Axiom
annotated source: temporal part of
annotated property: has associated axiom(nl)
annotated target: if b proper_temporal_part_of c, then there is some d which is a proper_temporal_part_of c and which shares no parts with b. (axiom label in BFO2 Reference: [117-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/117-002

Axiom
annotated source: temporal part of
annotated property: has associated axiom(fol)
annotated target: (forall (x y) (if (properTemporalPartOf x y) (exists (z) (and (properTemporalPartOf z y) (not (exists (w) (and (temporalPartOf w x) (temporalPartOf w z)))))))) // axiom label in BFO2 CLIF: [117-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/117-002

Axiom
annotated source: temporal part of
annotated property: has associated axiom(fol)
annotated target: (iff (properTemporalPartOf a b) (and (temporalPartOf a b) (not (= a b)))) // axiom label in BFO2 CLIF: [116-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/116-001

Axiom
annotated source: temporal part of
annotated property: has associated axiom(fol)
annotated target: (iff (temporalPartOf a b) (and (occurrentPartOf a b) (exists (t) (and (TemporalRegion t) (occupiesSpatioTemporalRegion a t))) (forall (c t_1) (if (and (Occurrent c) (occupiesSpatioTemporalRegion c t_1) (occurrentPartOf t_1 r)) (iff (occurrentPartOf c a) (occurrentPartOf c b)))))) // axiom label in BFO2 CLIF: [078-003]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/078-003

projects onto spatial region at some time
type: ObjectProperty
inverse of: spatial projection of spatiotemporal at some time
domain: spatiotemporal region
range: spatial region
BFO OWL specification label: st-projects-onto-s_st

spatial projection of spatiotemporal at some time
type: ObjectProperty
domain: spatial region
range: spatiotemporal region
BFO OWL specification label: s-projection-of-st_st

projects onto temporal region
type: ObjectProperty
sub property of: exists at
inverse of: temporal projection of spatiotemporal
domain: spatiotemporal region
range: temporal region
BFO OWL specification label: st-projects-onto-t

temporal projection of spatiotemporal
type: ObjectProperty
sub property of: during which exists
domain: temporal region
range: spatiotemporal region
BFO OWL specification label: t-projection-of-st

occupies temporal region
type: ObjectProperty
sub property of: exists at
inverse of: has temporal occupant
domain: occurrent
range: temporal region
BFO OWL specification label: spans
BFO CLIF specification label: occupiesTemporalRegion
elucidation: p occupies_temporal_region t. This is a primitive relation between an occurrent p and the temporal region t upon which the spatiotemporal region p occupies_spatiotemporal_region projects. (axiom label in BFO2 Reference: [132-001])

Axiom
annotated source: occupies temporal region
annotated property: elucidation
annotated target: p occupies_temporal_region t. This is a primitive relation between an occurrent p and the temporal region t upon which the spatiotemporal region p occupies_spatiotemporal_region projects. (axiom label in BFO2 Reference: [132-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/132-001

has temporal occupant
type: ObjectProperty
sub property of: during which exists
domain: temporal region
range: occurrent
BFO OWL specification label: span-of
BFO CLIF specification label: spanOf
elucidation: [copied from inverse property 'occupies temporal region'] p occupies_temporal_region t. This is a primitive relation between an occurrent p and the temporal region t upon which the spatiotemporal region p occupies_spatiotemporal_region projects. (axiom label in BFO2 Reference: [132-001])

during which exists
type: ObjectProperty
domain: temporal region
range: entity
BFO OWL specification label: during-which-exists
editor note: [copied from inverse property 'exists at'] BFO2 Reference: entity
editor note: [copied from inverse property 'exists at'] BFO2 Reference: temporal region
elucidation: [copied from inverse property 'exists at'] b exists_at t means: b is an entity which exists at some temporal region t. (axiom label in BFO2 Reference: [118-002])

bearer of at all times
type: ObjectProperty
sub property of: has specific dependent at all times
domain: Class
range: specifically dependent continuant
BFO OWL specification label: bearer-of_at
BFO CLIF specification label: bearerOfAt
definition: b bearer_of c at t =Def. c s-depends_on b at t & b is an independent continuant that is not a spatial region. (axiom label in BFO2 Reference: [053-004])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'bearer of at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'bearer of@en(x,y,t)'.
editor note: BFO2 Reference: independent continuant that is not a spatial region
editor note: BFO2 Reference: specifically dependent continuant
has associated axiom(fol): (iff (bearerOfAt a b t) (and (specificallyDependsOnAt b a t) (IndependentContinuant a) (not (SpatialRegion a)) (existsAt b t))) // axiom label in BFO2 CLIF: [053-004]

Axiom
annotated source: bearer of at all times
annotated property: definition
annotated target: b bearer_of c at t =Def. c s-depends_on b at t & b is an independent continuant that is not a spatial region. (axiom label in BFO2 Reference: [053-004])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/053-004

Axiom
annotated source: bearer of at all times
annotated property: has associated axiom(fol)
annotated target: (iff (bearerOfAt a b t) (and (specificallyDependsOnAt b a t) (IndependentContinuant a) (not (SpatialRegion a)) (existsAt b t))) // axiom label in BFO2 CLIF: [053-004]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/053-004

has quality at all times
type: ObjectProperty
sub property of: bearer of at all times
range: quality
BFO OWL specification label: has-q_at

has function at all times
type: ObjectProperty
sub property of: bearer of at all times
range: function
BFO OWL specification label: has-f_at
BFO CLIF specification label: hasFunctionAt
definition: a has_function b at t =Def. b function_of a at t. (axiom label in BFO2 Reference: [070-001])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'has function at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'has function@en(x,y,t)'.
has associated axiom(fol): (iff (hasFunctionAt a b t) (functionOf b a t)) // axiom label in BFO2 CLIF: [070-001]

Axiom
annotated source: has function at all times
annotated property: definition
annotated target: a has_function b at t =Def. b function_of a at t. (axiom label in BFO2 Reference: [070-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/070-001

Axiom
annotated source: has function at all times
annotated property: has associated axiom(fol)
annotated target: (iff (hasFunctionAt a b t) (functionOf b a t)) // axiom label in BFO2 CLIF: [070-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/070-001

has role at all times
type: ObjectProperty
sub property of: bearer of at all times
range: role
BFO OWL specification label: has-r_at
BFO CLIF specification label: hasRoleAt
definition: a has_role b at t =Def. b role_of a at t. (axiom label in BFO2 Reference: [068-001])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'has role at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'has role@en(x,y,t)'.
has associated axiom(fol): (iff (hasRoleAt a b t) (roleOfAt b a t)) // axiom label in BFO2 CLIF: [068-001]

Axiom
annotated source: has role at all times
annotated property: definition
annotated target: a has_role b at t =Def. b role_of a at t. (axiom label in BFO2 Reference: [068-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/068-001

Axiom
annotated source: has role at all times
annotated property: has associated axiom(fol)
annotated target: (iff (hasRoleAt a b t) (roleOfAt b a t)) // axiom label in BFO2 CLIF: [068-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/068-001

has disposition at all times
type: ObjectProperty
sub property of: bearer of at all times
range: disposition
BFO OWL specification label: has-d_at
BFO CLIF specification label: hasDispositionAt
definition: a has_disposition b at t =Def. b disposition_of a at t. (axiom label in BFO2 Reference: [069-001])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'has disposition at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'has disposition@en(x,y,t)'.
has associated axiom(fol): (iff (hasDispositionAt a b t) (dispositionOf b a t)) // axiom label in BFO2 CLIF: [069-001]

Axiom
annotated source: has disposition at all times
annotated property: definition
annotated target: a has_disposition b at t =Def. b disposition_of a at t. (axiom label in BFO2 Reference: [069-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/069-001

Axiom
annotated source: has disposition at all times
annotated property: has associated axiom(fol)
annotated target: (iff (hasDispositionAt a b t) (dispositionOf b a t)) // axiom label in BFO2 CLIF: [069-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/069-001

material basis of at all times
type: ObjectProperty
sub property of: material basis of at some time
domain: material entity
range: disposition
BFO OWL specification label: material-basis-of_at

concretizes at all times
type: ObjectProperty
sub property of: concretizes at some time
BFO OWL specification label: concretizes_at
BFO CLIF specification label: concretizesAt
example of usage: You may concretize a piece of software by installing it in your computer
example of usage: You may concretize a recipe that you find in a cookbook by turning it into a plan which exists as a realizable dependent continuant in your head.
example of usage: you may concretize a poem as a pattern of memory traces in your head
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'concretizes at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'concretizes@en(x,y,t)'.
elucidation: b concretizes c at t means: b is a specifically dependent continuant & c is a generically dependent continuant & for some independent continuant that is not a spatial region d, b s-depends_on d at t & c g-depends on d at t & if c migrates from bearer d to another bearer e than a copy of b will be created in e. (axiom label in BFO2 Reference: [075-002])
has associated axiom(nl): if b g-depends on c at some time t, then there is some d, such that d concretizes b at t and d s-depends_on c at t. (axiom label in BFO2 Reference: [076-001])
has associated axiom(fol): (forall (x y t) (if (concretizesAt x y t) (and (SpecificallyDependentContinuant x) (GenericallyDependentContinuant y) (exists (z) (and (IndependentContinuant z) (specificallyDependsOnAt x z t) (genericallyDependsOnAt y z t)))))) // axiom label in BFO2 CLIF: [075-002]
has associated axiom(fol): (forall (x y t) (if (genericallyDependsOnAt x y t) (exists (z) (and (concretizesAt z x t) (specificallyDependsOnAt z y t))))) // axiom label in BFO2 CLIF: [076-001]

Axiom
annotated source: concretizes at all times
annotated property: elucidation
annotated target: b concretizes c at t means: b is a specifically dependent continuant & c is a generically dependent continuant & for some independent continuant that is not a spatial region d, b s-depends_on d at t & c g-depends on d at t & if c migrates from bearer d to another bearer e than a copy of b will be created in e. (axiom label in BFO2 Reference: [075-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/075-002

Axiom
annotated source: concretizes at all times
annotated property: has associated axiom(nl)
annotated target: if b g-depends on c at some time t, then there is some d, such that d concretizes b at t and d s-depends_on c at t. (axiom label in BFO2 Reference: [076-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/076-001

Axiom
annotated source: concretizes at all times
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (concretizesAt x y t) (and (SpecificallyDependentContinuant x) (GenericallyDependentContinuant y) (exists (z) (and (IndependentContinuant z) (specificallyDependsOnAt x z t) (genericallyDependsOnAt y z t)))))) // axiom label in BFO2 CLIF: [075-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/075-002

Axiom
annotated source: concretizes at all times
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (genericallyDependsOnAt x y t) (exists (z) (and (concretizesAt z x t) (specificallyDependsOnAt z y t))))) // axiom label in BFO2 CLIF: [076-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/076-001

concretized by at all times
type: ObjectProperty
sub property of: concretized by at some time
BFO OWL specification label: concretized-by_at

participates in at all times
type: ObjectProperty
sub property of: participates in at some time
BFO OWL specification label: participates-in_at
BFO CLIF specification label: participatesInAt

has participant at all times
type: ObjectProperty
sub property of: has participant at some time
domain: process
range: Class
  intersection of: continuant
  intersection of: Class
    complement of: spatial region
BFO OWL specification label: has-participant_at
BFO CLIF specification label: hasParticipantAt
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'has participant at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'has participant@en(x,y,t)'.
editor note: BFO 2 Reference: Spatial regions do not participate in processes.
editor note: BFO2 Reference: independent continuant that is not a spatial region, specifically dependent continuant, generically dependent continuant
editor note: BFO2 Reference: process
elucidation: has_participant is an instance-level relation between a process, a continuant, and a temporal region at which the continuant participates in some way in the process. (axiom label in BFO2 Reference: [086-003])
has associated axiom(nl): if b has_participant c at t & c is a generically dependent continuant, then there is some independent continuant that is not a spatial region d, and which is such that c g-depends on d at t & b s-depends_on d at t. (axiom label in BFO2 Reference: [091-003])
has associated axiom(nl): if b has_participant c at t & c is a specifically dependent continuant, then there is some independent continuant that is not a spatial region d, c s-depends_on d at t & b s-depends_on d at t. (axiom label in BFO2 Reference: [090-003])
has associated axiom(nl): if b has_participant c at t then b is an occurrent. (axiom label in BFO2 Reference: [087-001])
has associated axiom(nl): if b has_participant c at t then c exists at t. (axiom label in BFO2 Reference: [089-001])
has associated axiom(nl): if b has_participant c at t then c is a continuant. (axiom label in BFO2 Reference: [088-001])
has associated axiom(fol): (forall (x y t) (if (and (hasParticipantAt x y t) (GenericallyDependentContinuant y)) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (genericallyDependsOn y z t) (specificallyDependsOnAt x z t))))) // axiom label in BFO2 CLIF: [091-003]
has associated axiom(fol): (forall (x y t) (if (and (hasParticipantAt x y t) (SpecificallyDependentContinuant y)) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (specificallyDependsOnAt x z t) (specificallyDependsOnAt y z t))))) // axiom label in BFO2 CLIF: [090-003]
has associated axiom(fol): (forall (x y t) (if (hasParticipantAt x y t) (Continuant y))) // axiom label in BFO2 CLIF: [088-001]
has associated axiom(fol): (forall (x y t) (if (hasParticipantAt x y t) (Occurrent x))) // axiom label in BFO2 CLIF: [087-001]
has associated axiom(fol): (forall (x y t) (if (hasParticipantAt x y t) (existsAt y t))) // axiom label in BFO2 CLIF: [089-001]

Axiom
annotated source: has participant at all times
annotated property: elucidation
annotated target: has_participant is an instance-level relation between a process, a continuant, and a temporal region at which the continuant participates in some way in the process. (axiom label in BFO2 Reference: [086-003])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/086-003

Axiom
annotated source: has participant at all times
annotated property: has associated axiom(nl)
annotated target: if b has_participant c at t & c is a generically dependent continuant, then there is some independent continuant that is not a spatial region d, and which is such that c g-depends on d at t & b s-depends_on d at t. (axiom label in BFO2 Reference: [091-003])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/091-003

Axiom
annotated source: has participant at all times
annotated property: has associated axiom(nl)
annotated target: if b has_participant c at t & c is a specifically dependent continuant, then there is some independent continuant that is not a spatial region d, c s-depends_on d at t & b s-depends_on d at t. (axiom label in BFO2 Reference: [090-003])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/090-003

Axiom
annotated source: has participant at all times
annotated property: has associated axiom(nl)
annotated target: if b has_participant c at t then b is an occurrent. (axiom label in BFO2 Reference: [087-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/087-001

Axiom
annotated source: has participant at all times
annotated property: has associated axiom(nl)
annotated target: if b has_participant c at t then c exists at t. (axiom label in BFO2 Reference: [089-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/089-001

Axiom
annotated source: has participant at all times
annotated property: has associated axiom(nl)
annotated target: if b has_participant c at t then c is a continuant. (axiom label in BFO2 Reference: [088-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/088-001

Axiom
annotated source: has participant at all times
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (and (hasParticipantAt x y t) (GenericallyDependentContinuant y)) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (genericallyDependsOn y z t) (specificallyDependsOnAt x z t))))) // axiom label in BFO2 CLIF: [091-003]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/091-003

Axiom
annotated source: has participant at all times
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (and (hasParticipantAt x y t) (SpecificallyDependentContinuant y)) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (specificallyDependsOnAt x z t) (specificallyDependsOnAt y z t))))) // axiom label in BFO2 CLIF: [090-003]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/090-003

Axiom
annotated source: has participant at all times
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (hasParticipantAt x y t) (Continuant y))) // axiom label in BFO2 CLIF: [088-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/088-001

Axiom
annotated source: has participant at all times
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (hasParticipantAt x y t) (Occurrent x))) // axiom label in BFO2 CLIF: [087-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/087-001

Axiom
annotated source: has participant at all times
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (hasParticipantAt x y t) (existsAt y t))) // axiom label in BFO2 CLIF: [089-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/089-001

has specific dependent at all times
type: ObjectProperty
sub property of: has specific dependent at some time
BFO OWL specification label: has-s-dep_at

specifically depends on at some time
type: ObjectProperty
domain: Class
range: Class
BFO OWL specification label: s-depends-on_st
BFO CLIF specification label: specificallyDependsOn
example of usage: A pain s-depends_on the organism that is experiencing the pain
example of usage: a gait s-depends_on the walking object. (All at some specific time.)
example of usage: a shape s-depends_on the shaped object
example of usage: one-sided s-dependence of a dependent continuant on an independent continuant: an instance of headache s-depends_on some head
example of usage: one-sided s-dependence of a dependent continuant on an independent continuant: an instance of temperature s-depends_on some organism
example of usage: one-sided s-dependence of a process on something: a process of cell death s-depends_on a cell
example of usage: one-sided s-dependence of a process on something: an instance of seeing (a relational process) s-depends_on some organism and on some seen entity, which may be an occurrent or a continuant
example of usage: one-sided s-dependence of one occurrent on another: a process of answering a question is dependent on a prior process of asking a question
example of usage: one-sided s-dependence of one occurrent on another: a process of obeying a command is dependent on a prior process of issuing a command
example of usage: one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of hitting a ball with a cricket bat
example of usage: one-sided s-dependence of one occurrent on multiple independent continuants: a relational process of paying cash to a merchant in exchange for a bag of figs
example of usage: reciprocal s-dependence between occurrents: a process of buying and the associated process of selling
example of usage: reciprocal s-dependence between occurrents: a process of increasing the volume of a portion of gas while temperature remains constant and the associated process of decreasing the pressure exerted by the gas
example of usage: reciprocal s-dependence between occurrents: in a game of chess the process of playing with the white pieces is mutually dependent on the process of playing with the black pieces
example of usage: the one-sided dependence of an occurrent on an independent continuant: football match on the players, the ground, the ball
example of usage: the one-sided dependence of an occurrent on an independent continuant: handwave on a hand
example of usage: the three-sided reciprocal s-dependence of the hue, saturation and brightness of a color [45
example of usage: the three-sided reciprocal s-dependence of the pitch, timbre and volume of a tone [45
example of usage: the two-sided reciprocal s-dependence of the roles of husband and wife [20
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'specifically depends on at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'specifically depends on@en'(x,y,t)
editor note: BFO 2 Reference: An entity – for example an act of communication or a game of football – can s-depends_on more than one entity. Complex phenomena for example in the psychological and social realms (such as inferring, commanding and requesting) or in the realm of multi-organismal biological processes (such as infection and resistance), will involve multiple families of dependence relations, involving both continuants and occurrents [1, 4, 28
editor note: BFO 2 Reference: S-dependence is just one type of dependence among many; it is what, in the literature, is referred to as ‘existential dependence’ [87, 46, 65, 20
editor note: BFO 2 Reference: the relation of s-depends_on does not in every case require simultaneous existence of its relata. Note the difference between such cases and the cases of continuant universals defined historically: the act of answering depends existentially on the prior act of questioning; the human being who was baptized or who answered a question does not himself depend existentially on the prior act of baptism or answering. He would still exist even if these acts had never taken place.
editor note: BFO2 Reference: specifically dependent continuant\; process; process boundary
elucidation: To say that b s-depends_on a at t is to say that b and c do not share common parts & b is of its nature such that it cannot exist unless c exists & b is not a boundary of c and b is not a site of which c is the host [64
has associated axiom(nl): If b is s-depends_on something at some time, then b is not a material entity. (axiom label in BFO2 Reference: [052-001])
has associated axiom(nl): If b s-depends_on something at t, then there is some c, which is an independent continuant and not a spatial region, such that b s-depends_on c at t. (axiom label in BFO2 Reference: [136-001])
has associated axiom(nl): If occurrent b s-depends_on some independent continuant c at t, then b s-depends_on c at every time at which b exists. (axiom label in BFO2 Reference: [015-002])
has associated axiom(nl): an entity does not s-depend_on any of its (continuant or occurrent) parts or on anything it is part of. (axiom label in BFO2 Reference: [013-002])
has associated axiom(nl): if b s-depends_on c at t & c s-depends_on d at t then b s-depends_on d at t. (axiom label in BFO2 Reference: [054-002])
has associated axiom(fol): (forall (x y t) (if (and (Entity x) (or (continuantPartOfAt y x t) (continuantPartOfAt x y t) (occurrentPartOf x y) (occurrentPartOf y x))) (not (specificallyDependsOnAt x y t)))) // axiom label in BFO2 CLIF: [013-002]
has associated axiom(fol): (forall (x y t) (if (and (Occurrent x) (IndependentContinuant y) (specificallyDependsOnAt x y t)) (forall (t_1) (if (existsAt x t_1) (specificallyDependsOnAt x y t_1))))) // axiom label in BFO2 CLIF: [015-002]
has associated axiom(fol): (forall (x y t) (if (specificallyDependsOnAt x y t) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (specificallyDependsOnAt x z t))))) // axiom label in BFO2 CLIF: [136-001]
has associated axiom(fol): (forall (x y z t) (if (and (specificallyDependsOnAt x y t) (specificallyDependsOnAt y z t)) (specificallyDependsOnAt x z t))) // axiom label in BFO2 CLIF: [054-002]
has associated axiom(fol): (forall (x) (if (exists (y t) (specificallyDependsOnAt x y t)) (not (MaterialEntity x)))) // axiom label in BFO2 CLIF: [052-001]

Axiom
annotated source: specifically depends on at some time
annotated property: has associated axiom(nl)
annotated target: If b is s-depends_on something at some time, then b is not a material entity. (axiom label in BFO2 Reference: [052-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/052-001

Axiom
annotated source: specifically depends on at some time
annotated property: has associated axiom(nl)
annotated target: If b s-depends_on something at t, then there is some c, which is an independent continuant and not a spatial region, such that b s-depends_on c at t. (axiom label in BFO2 Reference: [136-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/136-001

Axiom
annotated source: specifically depends on at some time
annotated property: has associated axiom(nl)
annotated target: If occurrent b s-depends_on some independent continuant c at t, then b s-depends_on c at every time at which b exists. (axiom label in BFO2 Reference: [015-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/015-002

Axiom
annotated source: specifically depends on at some time
annotated property: has associated axiom(nl)
annotated target: an entity does not s-depend_on any of its (continuant or occurrent) parts or on anything it is part of. (axiom label in BFO2 Reference: [013-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/013-002

Axiom
annotated source: specifically depends on at some time
annotated property: has associated axiom(nl)
annotated target: if b s-depends_on c at t & c s-depends_on d at t then b s-depends_on d at t. (axiom label in BFO2 Reference: [054-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/054-002

Axiom
annotated source: specifically depends on at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (and (Entity x) (or (continuantPartOfAt y x t) (continuantPartOfAt x y t) (occurrentPartOf x y) (occurrentPartOf y x))) (not (specificallyDependsOnAt x y t)))) // axiom label in BFO2 CLIF: [013-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/013-002

Axiom
annotated source: specifically depends on at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (and (Occurrent x) (IndependentContinuant y) (specificallyDependsOnAt x y t)) (forall (t_1) (if (existsAt x t_1) (specificallyDependsOnAt x y t_1))))) // axiom label in BFO2 CLIF: [015-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/015-002

Axiom
annotated source: specifically depends on at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (specificallyDependsOnAt x y t) (exists (z) (and (IndependentContinuant z) (not (SpatialRegion z)) (specificallyDependsOnAt x z t))))) // axiom label in BFO2 CLIF: [136-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/136-001

Axiom
annotated source: specifically depends on at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x y z t) (if (and (specificallyDependsOnAt x y t) (specificallyDependsOnAt y z t)) (specificallyDependsOnAt x z t))) // axiom label in BFO2 CLIF: [054-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/054-002

Axiom
annotated source: specifically depends on at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (exists (y t) (specificallyDependsOnAt x y t)) (not (MaterialEntity x)))) // axiom label in BFO2 CLIF: [052-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/052-001

has location at all times
type: ObjectProperty
sub property of: has location at some time
type: TransitiveProperty
BFO OWL specification label: has-location_at

located in at some time
type: ObjectProperty
domain: independent continuant
range: independent continuant
BFO OWL specification label: located-in_st
BFO CLIF specification label: locatedInAt
example of usage: Mary located_in Salzburg
example of usage: the Empire State Building located_in New York.
example of usage: this portion of cocaine located_in this portion of blood
example of usage: this stem cell located_in this portion of bone marrow
example of usage: your arm located_in your body
definition: b located_in c at t = Def. b and c are independent continuants, and the region at which b is located at t is a (proper or improper) continuant_part_of the region at which c is located at t. (axiom label in BFO2 Reference: [045-001])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'located in at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'located in@en'(x,y,t)
editor note: BFO2 Reference: independent continuant
has associated axiom(nl): Located_in is transitive. (axiom label in BFO2 Reference: [046-001])
has associated axiom(nl): for all independent continuants b, c, and d: if b continuant_part_of c at t & c located_in d at t, then b located_in d at t. (axiom label in BFO2 Reference: [048-001])
has associated axiom(nl): for all independent continuants b, c, and d: if b located_in c at t & c continuant_part_of d at t, then b located_in d at t. (axiom label in BFO2 Reference: [049-001])
has associated axiom(fol): (forall (x y z t) (if (and (IndependentContinuant x) (IndependentContinuant y) (IndependentContinuant z) (continuantPartOfAt x y t) (locatedInAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [048-001]
has associated axiom(fol): (forall (x y z t) (if (and (IndependentContinuant x) (IndependentContinuant y) (IndependentContinuant z) (locatedInAt x y t) (continuantPartOfAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [049-001]
has associated axiom(fol): (forall (x y z t) (if (and (locatedInAt x y t) (locatedInAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [046-001]
has associated axiom(fol): (iff (locatedInAt a b t) (and (IndependentContinuant a) (IndependentContinuant b) (exists (r_1 r_2) (and (occupiesSpatialRegionAt a r_1 t) (occupiesSpatialRegionAt b r_2 t) (continuantPartOfAt r_1 r_2 t))))) // axiom label in BFO2 CLIF: [045-001]

Axiom
annotated source: located in at some time
annotated property: definition
annotated target: b located_in c at t = Def. b and c are independent continuants, and the region at which b is located at t is a (proper or improper) continuant_part_of the region at which c is located at t. (axiom label in BFO2 Reference: [045-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/045-001

Axiom
annotated source: located in at some time
annotated property: has associated axiom(nl)
annotated target: Located_in is transitive. (axiom label in BFO2 Reference: [046-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/046-001

Axiom
annotated source: located in at some time
annotated property: has associated axiom(nl)
annotated target: for all independent continuants b, c, and d: if b continuant_part_of c at t & c located_in d at t, then b located_in d at t. (axiom label in BFO2 Reference: [048-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/048-001

Axiom
annotated source: located in at some time
annotated property: has associated axiom(nl)
annotated target: for all independent continuants b, c, and d: if b located_in c at t & c continuant_part_of d at t, then b located_in d at t. (axiom label in BFO2 Reference: [049-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/049-001

Axiom
annotated source: located in at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x y z t) (if (and (IndependentContinuant x) (IndependentContinuant y) (IndependentContinuant z) (continuantPartOfAt x y t) (locatedInAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [048-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/048-001

Axiom
annotated source: located in at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x y z t) (if (and (IndependentContinuant x) (IndependentContinuant y) (IndependentContinuant z) (locatedInAt x y t) (continuantPartOfAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [049-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/049-001

Axiom
annotated source: located in at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x y z t) (if (and (locatedInAt x y t) (locatedInAt y z t)) (locatedInAt x z t))) // axiom label in BFO2 CLIF: [046-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/046-001

Axiom
annotated source: located in at some time
annotated property: has associated axiom(fol)
annotated target: (iff (locatedInAt a b t) (and (IndependentContinuant a) (IndependentContinuant b) (exists (r_1 r_2) (and (occupiesSpatialRegionAt a r_1 t) (occupiesSpatialRegionAt b r_2 t) (continuantPartOfAt r_1 r_2 t))))) // axiom label in BFO2 CLIF: [045-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/045-001

has member part at all times
type: ObjectProperty
sub property of: has continuant part at all times
sub property of: has proper continuant part at all times
sub property of: has member part at some time
BFO OWL specification label: has-member-part_at

member part of at all times
type: ObjectProperty
sub property of: member part of at some time
sub property of: proper part of continuant at all times
sub property of: part of continuant at all times
BFO OWL specification label: member-part-of_at
BFO CLIF specification label: memberPartOfAt
example of usage: each piece in a chess set is a member part of the chess set; each Beatle in the collection called The Beatles is a member part of The Beatles.
example of usage: each tree in a forest is a member_part of the forest
definition: b member_part_of c at t =Def. b is an object & there is at t a mutually exhaustive and pairwise disjoint partition of c into objects x1, …, xn (for some n > 1) with b = xi for some 1 ? i ? n. (axiom label in BFO2 Reference: [026-004])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'member part of at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'member part of@en(x,y,t)'.
editor note: BFO2 Reference: object
editor note: BFO2 Reference: object aggregate
has associated axiom(nl): if b member_part_of c at t then b continuant_part_of c at t. (axiom label in BFO2 Reference: [104-001])
has associated axiom(fol): (forall (x y t) (if (memberPartOfAt x y t) (continuantPartOfAt x y t))) // axiom label in BFO2 CLIF: [104-001]

Axiom
annotated source: member part of at all times
annotated property: definition
annotated target: b member_part_of c at t =Def. b is an object & there is at t a mutually exhaustive and pairwise disjoint partition of c into objects x1, …, xn (for some n > 1) with b = xi for some 1 ? i ? n. (axiom label in BFO2 Reference: [026-004])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/026-004

Axiom
annotated source: member part of at all times
annotated property: has associated axiom(nl)
annotated target: if b member_part_of c at t then b continuant_part_of c at t. (axiom label in BFO2 Reference: [104-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/104-001

Axiom
annotated source: member part of at all times
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (memberPartOfAt x y t) (continuantPartOfAt x y t))) // axiom label in BFO2 CLIF: [104-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/104-001

has proper continuant part at some time
type: ObjectProperty
sub property of: has continuant part at some time
inverse of: proper part of continuant at some time
domain: continuant
range: continuant
BFO OWL specification label: c-has-ppart_st
BFO CLIF specification label: hasProperContinuantPartAt
definition: [copied from inverse property 'proper part of continuant at some time'] b proper_continuant_part_of c at t =Def. b continuant_part_of c at t & b and c are not identical. (axiom label in BFO2 Reference: [004-001])
definition: b has_proper_continuant_part c at t = Def. c proper_continuant_part_of b at t. [XXX-001
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has proper continuant part at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has proper continuant part@en'(x,y,t)
editor note: [copied from inverse property 'proper part of continuant at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'proper part of continuant at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'proper part of continuant@en'(x,y,t)

proper part of continuant at some time
type: ObjectProperty
sub property of: part of continuant at some time
domain: continuant
range: continuant
BFO OWL specification label: c-ppart-of_st
BFO CLIF specification label: properContinuantPartOfAt
definition: [copied from inverse property 'has proper continuant part at some time'] b has_proper_continuant_part c at t = Def. c proper_continuant_part_of b at t. [XXX-001
definition: b proper_continuant_part_of c at t =Def. b continuant_part_of c at t & b and c are not identical. (axiom label in BFO2 Reference: [004-001])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'proper part of continuant at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'proper part of continuant@en'(x,y,t)
editor note: [copied from inverse property 'has proper continuant part at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has proper continuant part at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has proper continuant part@en'(x,y,t)
has associated axiom(fol): (iff (properContinuantPartOfAt a b t) (and (continuantPartOfAt a b t) (not (= a b)))) // axiom label in BFO2 CLIF: [004-001]

Axiom
annotated source: proper part of continuant at some time
annotated property: definition
annotated target: b proper_continuant_part_of c at t =Def. b continuant_part_of c at t & b and c are not identical. (axiom label in BFO2 Reference: [004-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/004-001

Axiom
annotated source: proper part of continuant at some time
annotated property: has associated axiom(fol)
annotated target: (iff (properContinuantPartOfAt a b t) (and (continuantPartOfAt a b t) (not (= a b)))) // axiom label in BFO2 CLIF: [004-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/004-001

part of continuant at some time
type: ObjectProperty
inverse of: has continuant part at some time
domain: continuant
range: continuant
BFO OWL specification label: c-part-of_st
BFO CLIF specification label: continuantPartOfAt
example of usage: Mary’s arm continuant_part_of Mary in the time of her life prior to her operation
example of usage: the Northern hemisphere of the planet Earth is a part of the planet Earth at all times at which the planet Earth exists.
definition: [copied from inverse property 'has continuant part at some time'] b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'part of continuant at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'part of continuant@en'(x,y,t)
editor note: BFO 2 Reference: Immaterial entities are in some cases continuant parts of their material hosts. Thus the hold of a ship, for example, is a part of the ship; it may itself have parts, which may have names (used for example by ship stow planners, customs inspectors, and the like). Immaterial entities under both 1. and 2. can be of zero, one, two or three dimensions. We define:a(immaterial entity)[Definition: a is an immaterial entity = Def. a is an independent continuant that has no material entities as parts. (axiom label in BFO2 Reference: [028-001])
editor note: BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion.
editor note: BFO2 Reference: continuant
editor note: BFO2 Reference: continuantThe range for ‘t’ (as in all cases throughout this document unless otherwise specified) is: temporal region.
editor note: [copied from inverse property 'has continuant part at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has continuant part at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has continuant part@en'(x,y,t)
elucidation: b continuant_part_of c at t =Def. b is a part of c at t & t is a time & b and c are continuants. (axiom label in BFO2 Reference: [002-001])
has associated axiom(nl): continuant_part_of is antisymmetric. (axiom label in BFO2 Reference: [120-001])
has associated axiom(nl): continuant_part_of is reflexive (every continuant entity is a continuant_part_of itself). (axiom label in BFO2 Reference: [111-002])
has associated axiom(nl): continuant_part_of is transitive. (axiom label in BFO2 Reference: [110-001])
has associated axiom(nl): continuant_part_of satisfies unique product. (axiom label in BFO2 Reference: [122-001])
has associated axiom(nl): continuant_part_of satisfies weak supplementation. (axiom label in BFO2 Reference: [121-001])
has associated axiom(nl): if b continuant_part_of c at t and b is an independent continuant, then b is located_in c at t. (axiom label in BFO2 Reference: [047-002])
has associated axiom(fol): (forall (x t) (if (Continuant x) (continuantPartOfAt x x t))) // axiom label in BFO2 CLIF: [111-002]
has associated axiom(fol): (forall (x y t) (if (and (continuantPartOfAt x y t) (IndependentContinuant x)) (locatedInAt x y t))) // axiom label in BFO2 CLIF: [047-002]
has associated axiom(fol): (forall (x y t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y x t)) (= x y))) // axiom label in BFO2 CLIF: [120-001]
has associated axiom(fol): (forall (x y t) (if (and (continuantPartOfAt x y t) (not (= x y))) (exists (z) (and (continuantPartOfAt z y t) (not (exists (w) (and (continuantPartOfAt w x t) (continuantPartOfAt w z t)))))))) // axiom label in BFO2 CLIF: [121-001]
has associated axiom(fol): (forall (x y t) (if (exists (v) (and (continuantPartOfAt v x t) (continuantPartOfAt v y t))) (exists (z) (forall (u w) (iff (iff (continuantPartOfAt w u t) (and (continuantPartOfAt w x t) (continuantPartOfAt w y t))) (= z u)))))) // axiom label in BFO2 CLIF: [122-001]
has associated axiom(fol): (forall (x y z t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y z t)) (continuantPartOfAt x z t))) // axiom label in BFO2 CLIF: [110-001]
has associated axiom(fol): (iff (ImmaterialEntity a) (and (IndependentContinuant a) (not (exists (b t) (and (MaterialEntity b) (continuantPartOfAt b a t)))))) // axiom label in BFO2 CLIF: [028-001]

Axiom
annotated source: part of continuant at some time
annotated property: editor note
annotated target: BFO 2 Reference: Immaterial entities are in some cases continuant parts of their material hosts. Thus the hold of a ship, for example, is a part of the ship; it may itself have parts, which may have names (used for example by ship stow planners, customs inspectors, and the like). Immaterial entities under both 1. and 2. can be of zero, one, two or three dimensions. We define:a(immaterial entity)[Definition: a is an immaterial entity = Def. a is an independent continuant that has no material entities as parts. (axiom label in BFO2 Reference: [028-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/028-001

Axiom
annotated source: part of continuant at some time
annotated property: elucidation
annotated target: b continuant_part_of c at t =Def. b is a part of c at t & t is a time & b and c are continuants. (axiom label in BFO2 Reference: [002-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/002-001

Axiom
annotated source: part of continuant at some time
annotated property: has associated axiom(nl)
annotated target: continuant_part_of is antisymmetric. (axiom label in BFO2 Reference: [120-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/120-001

Axiom
annotated source: part of continuant at some time
annotated property: has associated axiom(nl)
annotated target: continuant_part_of is reflexive (every continuant entity is a continuant_part_of itself). (axiom label in BFO2 Reference: [111-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/111-002

Axiom
annotated source: part of continuant at some time
annotated property: has associated axiom(nl)
annotated target: continuant_part_of is transitive. (axiom label in BFO2 Reference: [110-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/110-001

Axiom
annotated source: part of continuant at some time
annotated property: has associated axiom(nl)
annotated target: continuant_part_of satisfies unique product. (axiom label in BFO2 Reference: [122-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/122-001

Axiom
annotated source: part of continuant at some time
annotated property: has associated axiom(nl)
annotated target: continuant_part_of satisfies weak supplementation. (axiom label in BFO2 Reference: [121-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/121-001

Axiom
annotated source: part of continuant at some time
annotated property: has associated axiom(nl)
annotated target: if b continuant_part_of c at t and b is an independent continuant, then b is located_in c at t. (axiom label in BFO2 Reference: [047-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/047-002

Axiom
annotated source: part of continuant at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x t) (if (Continuant x) (continuantPartOfAt x x t))) // axiom label in BFO2 CLIF: [111-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/111-002

Axiom
annotated source: part of continuant at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (and (continuantPartOfAt x y t) (IndependentContinuant x)) (locatedInAt x y t))) // axiom label in BFO2 CLIF: [047-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/047-002

Axiom
annotated source: part of continuant at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y x t)) (= x y))) // axiom label in BFO2 CLIF: [120-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/120-001

Axiom
annotated source: part of continuant at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (and (continuantPartOfAt x y t) (not (= x y))) (exists (z) (and (continuantPartOfAt z y t) (not (exists (w) (and (continuantPartOfAt w x t) (continuantPartOfAt w z t)))))))) // axiom label in BFO2 CLIF: [121-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/121-001

Axiom
annotated source: part of continuant at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (exists (v) (and (continuantPartOfAt v x t) (continuantPartOfAt v y t))) (exists (z) (forall (u w) (iff (iff (continuantPartOfAt w u t) (and (continuantPartOfAt w x t) (continuantPartOfAt w y t))) (= z u)))))) // axiom label in BFO2 CLIF: [122-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/122-001

Axiom
annotated source: part of continuant at some time
annotated property: has associated axiom(fol)
annotated target: (forall (x y z t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y z t)) (continuantPartOfAt x z t))) // axiom label in BFO2 CLIF: [110-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/110-001

Axiom
annotated source: part of continuant at some time
annotated property: has associated axiom(fol)
annotated target: (iff (ImmaterialEntity a) (and (IndependentContinuant a) (not (exists (b t) (and (MaterialEntity b) (continuantPartOfAt b a t)))))) // axiom label in BFO2 CLIF: [028-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/028-001

part of continuant at all times
type: ObjectProperty
sub property of: part of continuant at some time
inverse of: has continuant part at all times that part exists
type: TransitiveProperty
BFO OWL specification label: c-part-of_at
BFO CLIF specification label: continuantPartOfAt
example of usage: Mary’s arm continuant_part_of Mary in the time of her life prior to her operation
example of usage: the Northern hemisphere of the planet Earth is a part of the planet Earth at all times at which the planet Earth exists.
definition: [copied from inverse property 'has continuant part at all times that part exists'] forall(t) exists_at(y,t) -> exists_at(x,t) and 'has continuant part'(x,y,t)
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'part of continuant at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'part of continuant@en(x,y,t)'.
editor note: BFO 2 Reference: Immaterial entities are in some cases continuant parts of their material hosts. Thus the hold of a ship, for example, is a part of the ship; it may itself have parts, which may have names (used for example by ship stow planners, customs inspectors, and the like). Immaterial entities under both 1. and 2. can be of zero, one, two or three dimensions. We define:a(immaterial entity)[Definition: a is an immaterial entity = Def. a is an independent continuant that has no material entities as parts. (axiom label in BFO2 Reference: [028-001])
editor note: BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion.
editor note: BFO2 Reference: continuant
editor note: BFO2 Reference: continuantThe range for ‘t’ (as in all cases throughout this document unless otherwise specified) is: temporal region.
editor note: [copied from inverse property 'has continuant part at all times that part exists'] This is a binary version of a ternary time-indexed, instance level, relation. Unlike the rest of the temporalized relations which temporally quantify over existence of the subject of the relation, this relation temporally quantifies over the existence of the object of the relation. The relation is provided tentatively, to assess whether the GO needs such a relation. It is inverse of 'part of continuant at all times'
elucidation: b continuant_part_of c at t =Def. b is a part of c at t & t is a time & b and c are continuants. (axiom label in BFO2 Reference: [002-001])
has associated axiom(nl): continuant_part_of is antisymmetric. (axiom label in BFO2 Reference: [120-001])
has associated axiom(nl): continuant_part_of is reflexive (every continuant entity is a continuant_part_of itself). (axiom label in BFO2 Reference: [111-002])
has associated axiom(nl): continuant_part_of is transitive. (axiom label in BFO2 Reference: [110-001])
has associated axiom(nl): continuant_part_of satisfies unique product. (axiom label in BFO2 Reference: [122-001])
has associated axiom(nl): continuant_part_of satisfies weak supplementation. (axiom label in BFO2 Reference: [121-001])
has associated axiom(nl): if b continuant_part_of c at t and b is an independent continuant, then b is located_in c at t. (axiom label in BFO2 Reference: [047-002])
has associated axiom(fol): (forall (x t) (if (Continuant x) (continuantPartOfAt x x t))) // axiom label in BFO2 CLIF: [111-002]
has associated axiom(fol): (forall (x y t) (if (and (continuantPartOfAt x y t) (IndependentContinuant x)) (locatedInAt x y t))) // axiom label in BFO2 CLIF: [047-002]
has associated axiom(fol): (forall (x y t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y x t)) (= x y))) // axiom label in BFO2 CLIF: [120-001]
has associated axiom(fol): (forall (x y t) (if (and (continuantPartOfAt x y t) (not (= x y))) (exists (z) (and (continuantPartOfAt z y t) (not (exists (w) (and (continuantPartOfAt w x t) (continuantPartOfAt w z t)))))))) // axiom label in BFO2 CLIF: [121-001]
has associated axiom(fol): (forall (x y t) (if (exists (v) (and (continuantPartOfAt v x t) (continuantPartOfAt v y t))) (exists (z) (forall (u w) (iff (iff (continuantPartOfAt w u t) (and (continuantPartOfAt w x t) (continuantPartOfAt w y t))) (= z u)))))) // axiom label in BFO2 CLIF: [122-001]
has associated axiom(fol): (forall (x y z t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y z t)) (continuantPartOfAt x z t))) // axiom label in BFO2 CLIF: [110-001]
has associated axiom(fol): (iff (ImmaterialEntity a) (and (IndependentContinuant a) (not (exists (b t) (and (MaterialEntity b) (continuantPartOfAt b a t)))))) // axiom label in BFO2 CLIF: [028-001]

Axiom
annotated source: part of continuant at all times
annotated property: editor note
annotated target: BFO 2 Reference: Immaterial entities are in some cases continuant parts of their material hosts. Thus the hold of a ship, for example, is a part of the ship; it may itself have parts, which may have names (used for example by ship stow planners, customs inspectors, and the like). Immaterial entities under both 1. and 2. can be of zero, one, two or three dimensions. We define:a(immaterial entity)[Definition: a is an immaterial entity = Def. a is an independent continuant that has no material entities as parts. (axiom label in BFO2 Reference: [028-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/028-001

Axiom
annotated source: part of continuant at all times
annotated property: elucidation
annotated target: b continuant_part_of c at t =Def. b is a part of c at t & t is a time & b and c are continuants. (axiom label in BFO2 Reference: [002-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000601
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/002-001

Axiom
annotated source: part of continuant at all times
annotated property: has associated axiom(nl)
annotated target: continuant_part_of is antisymmetric. (axiom label in BFO2 Reference: [120-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/120-001

Axiom
annotated source: part of continuant at all times
annotated property: has associated axiom(nl)
annotated target: continuant_part_of is reflexive (every continuant entity is a continuant_part_of itself). (axiom label in BFO2 Reference: [111-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/111-002

Axiom
annotated source: part of continuant at all times
annotated property: has associated axiom(nl)
annotated target: continuant_part_of is transitive. (axiom label in BFO2 Reference: [110-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/110-001

Axiom
annotated source: part of continuant at all times
annotated property: has associated axiom(nl)
annotated target: continuant_part_of satisfies unique product. (axiom label in BFO2 Reference: [122-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/122-001

Axiom
annotated source: part of continuant at all times
annotated property: has associated axiom(nl)
annotated target: continuant_part_of satisfies weak supplementation. (axiom label in BFO2 Reference: [121-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/121-001

Axiom
annotated source: part of continuant at all times
annotated property: has associated axiom(nl)
annotated target: if b continuant_part_of c at t and b is an independent continuant, then b is located_in c at t. (axiom label in BFO2 Reference: [047-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/047-002

Axiom
annotated source: part of continuant at all times
annotated property: has associated axiom(fol)
annotated target: (forall (x t) (if (Continuant x) (continuantPartOfAt x x t))) // axiom label in BFO2 CLIF: [111-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/111-002

Axiom
annotated source: part of continuant at all times
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (and (continuantPartOfAt x y t) (IndependentContinuant x)) (locatedInAt x y t))) // axiom label in BFO2 CLIF: [047-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/047-002

Axiom
annotated source: part of continuant at all times
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y x t)) (= x y))) // axiom label in BFO2 CLIF: [120-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/120-001

Axiom
annotated source: part of continuant at all times
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (and (continuantPartOfAt x y t) (not (= x y))) (exists (z) (and (continuantPartOfAt z y t) (not (exists (w) (and (continuantPartOfAt w x t) (continuantPartOfAt w z t)))))))) // axiom label in BFO2 CLIF: [121-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/121-001

Axiom
annotated source: part of continuant at all times
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (exists (v) (and (continuantPartOfAt v x t) (continuantPartOfAt v y t))) (exists (z) (forall (u w) (iff (iff (continuantPartOfAt w u t) (and (continuantPartOfAt w x t) (continuantPartOfAt w y t))) (= z u)))))) // axiom label in BFO2 CLIF: [122-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/122-001

Axiom
annotated source: part of continuant at all times
annotated property: has associated axiom(fol)
annotated target: (forall (x y z t) (if (and (continuantPartOfAt x y t) (continuantPartOfAt y z t)) (continuantPartOfAt x z t))) // axiom label in BFO2 CLIF: [110-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/110-001

Axiom
annotated source: part of continuant at all times
annotated property: has associated axiom(fol)
annotated target: (iff (ImmaterialEntity a) (and (IndependentContinuant a) (not (exists (b t) (and (MaterialEntity b) (continuantPartOfAt b a t)))))) // axiom label in BFO2 CLIF: [028-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/028-001

has continuant part at some time
type: ObjectProperty
domain: continuant
range: continuant
BFO OWL specification label: c-has-part_st
BFO CLIF specification label: hasContinuantPartAt
example of usage: [copied from inverse property 'part of continuant at some time'] Mary’s arm continuant_part_of Mary in the time of her life prior to her operation
example of usage: [copied from inverse property 'part of continuant at some time'] the Northern hemisphere of the planet Earth is a part of the planet Earth at all times at which the planet Earth exists.
definition: b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001])
editor note: Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'has continuant part at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'has continuant part@en'(x,y,t)
editor note: [copied from inverse property 'part of continuant at some time'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance level, relation. The BFO reading of the binary relation 'part of continuant at some time@en' is: exists t, exists_at(x,t) & exists_at(y,t) & 'part of continuant@en'(x,y,t)
editor note: [copied from inverse property 'part of continuant at some time'] BFO 2 Reference: Immaterial entities are in some cases continuant parts of their material hosts. Thus the hold of a ship, for example, is a part of the ship; it may itself have parts, which may have names (used for example by ship stow planners, customs inspectors, and the like). Immaterial entities under both 1. and 2. can be of zero, one, two or three dimensions. We define:a(immaterial entity)[Definition: a is an immaterial entity = Def. a is an independent continuant that has no material entities as parts. (axiom label in BFO2 Reference: [028-001])
editor note: [copied from inverse property 'part of continuant at some time'] BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion.
editor note: [copied from inverse property 'part of continuant at some time'] BFO2 Reference: continuant
editor note: [copied from inverse property 'part of continuant at some time'] BFO2 Reference: continuantThe range for ‘t’ (as in all cases throughout this document unless otherwise specified) is: temporal region.
elucidation: [copied from inverse property 'part of continuant at some time'] b continuant_part_of c at t =Def. b is a part of c at t & t is a time & b and c are continuants. (axiom label in BFO2 Reference: [002-001])
has associated axiom(fol): (iff (hasContinuantPartAt a b t) (continuantPartOfAt b a t)) // axiom label in BFO2 CLIF: [006-001]

Axiom
annotated source: has continuant part at some time
annotated property: definition
annotated target: b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/006-001

Axiom
annotated source: has continuant part at some time
annotated property: has associated axiom(fol)
annotated target: (iff (hasContinuantPartAt a b t) (continuantPartOfAt b a t)) // axiom label in BFO2 CLIF: [006-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/006-001

has proper temporal part
type: ObjectProperty
sub property of: has proper occurrent part
sub property of: has temporal part
type: TransitiveProperty
domain: occurrent
range: occurrent
BFO OWL specification label: has-t-ppart

history of
type: ObjectProperty
sub property of: occurs in
sub property of: specifically depends on at all times
inverse of: has history
type: FunctionalProperty
type: InverseFunctionalProperty
domain: process
range: material entity
BFO OWL specification label: history-of
BFO CLIF specification label: historyOf
definition: [copied from inverse property 'has history'] b has_history c iff c history_of b [XXX-001
elucidation: b history_of c if c is a material entity or site and b is a history that is the unique history of cAxiom: if b history_of c and b history_of d then c=d [XXX-001

has history
type: ObjectProperty
sub property of: contains process
sub property of: participates in at all times
type: FunctionalProperty
type: InverseFunctionalProperty
domain: material entity
range: process
BFO OWL specification label: has-history
BFO CLIF specification label: hasHistory
definition: b has_history c iff c history_of b [XXX-001
elucidation: [copied from inverse property 'history of'] b history_of c if c is a material entity or site and b is a history that is the unique history of cAxiom: if b history_of c and b history_of d then c=d [XXX-001

part of continuant at all times that whole exists
type: ObjectProperty
sub property of: part of continuant at some time
type: TransitiveProperty
domain: continuant
range: continuant
BFO OWL specification label: c-part-of-object_at
definition: [copied from inverse property 'has continuant part at all times'] b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001])
definition: forall(t) exists_at(y,t) -> exists_at(x,t) and 'part of continuant'(x,y,t)
editor note: This is a binary version of a ternary time-indexed, instance level, relation. Unlike the rest of the temporalized relations which temporally quantify over existence of the subject of the relation, this relation temporally quantifies over the existence of the object of the relation. The relation is provided tentatively, to assess whether the GO needs such a relation. It is inverse of 'has continuant part at all times'
editor note: [copied from inverse property 'has continuant part at all times'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'has continuant part at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'has continuant part@en(x,y,t)'.

Axiom
annotated source: part of continuant at all times that whole exists
annotated property: definition
annotated target: forall(t) exists_at(y,t) -> exists_at(x,t) and 'part of continuant'(x,y,t)
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000598

Axiom
annotated source: part of continuant at all times that whole exists
annotated property: editor note
annotated target: This is a binary version of a ternary time-indexed, instance level, relation. Unlike the rest of the temporalized relations which temporally quantify over existence of the subject of the relation, this relation temporally quantifies over the existence of the object of the relation. The relation is provided tentatively, to assess whether the GO needs such a relation. It is inverse of 'has continuant part at all times'
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000599

has continuant part at all times that part exists
type: ObjectProperty
sub property of: has continuant part at some time
type: TransitiveProperty
domain: continuant
range: continuant
BFO OWL specification label: c-has-part-object_at
example of usage: [copied from inverse property 'part of continuant at all times'] Mary’s arm continuant_part_of Mary in the time of her life prior to her operation
example of usage: [copied from inverse property 'part of continuant at all times'] the Northern hemisphere of the planet Earth is a part of the planet Earth at all times at which the planet Earth exists.
definition: forall(t) exists_at(y,t) -> exists_at(x,t) and 'has continuant part'(x,y,t)
editor note: This is a binary version of a ternary time-indexed, instance level, relation. Unlike the rest of the temporalized relations which temporally quantify over existence of the subject of the relation, this relation temporally quantifies over the existence of the object of the relation. The relation is provided tentatively, to assess whether the GO needs such a relation. It is inverse of 'part of continuant at all times'
editor note: [copied from inverse property 'part of continuant at all times'] Alan Ruttenberg: This is a binary version of a ternary time-indexed, instance-level, relation. The BFO reading of the binary relation 'part of continuant at all times@en' is: forall(t) exists_at(x,t) -> exists_at(y,t) and 'part of continuant@en(x,y,t)'.
editor note: [copied from inverse property 'part of continuant at all times'] BFO 2 Reference: Immaterial entities are in some cases continuant parts of their material hosts. Thus the hold of a ship, for example, is a part of the ship; it may itself have parts, which may have names (used for example by ship stow planners, customs inspectors, and the like). Immaterial entities under both 1. and 2. can be of zero, one, two or three dimensions. We define:a(immaterial entity)[Definition: a is an immaterial entity = Def. a is an independent continuant that has no material entities as parts. (axiom label in BFO2 Reference: [028-001])
editor note: [copied from inverse property 'part of continuant at all times'] BFO 2 Reference: a (continuant or occurrent) part of itself. We appreciate that this is counterintuitive for some users, since it implies for example that President Obama is a part of himself. However it brings benefits in simplifying the logical formalism, and it captures an important feature of identity, namely that it is the limit case of mereological inclusion.
editor note: [copied from inverse property 'part of continuant at all times'] BFO2 Reference: continuant
editor note: [copied from inverse property 'part of continuant at all times'] BFO2 Reference: continuantThe range for ‘t’ (as in all cases throughout this document unless otherwise specified) is: temporal region.
elucidation: [copied from inverse property 'part of continuant at all times'] b continuant_part_of c at t =Def. b is a part of c at t & t is a time & b and c are continuants. (axiom label in BFO2 Reference: [002-001])

Axiom
annotated source: has continuant part at all times that part exists
annotated property: definition
annotated target: forall(t) exists_at(y,t) -> exists_at(x,t) and 'has continuant part'(x,y,t)
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000599
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000601

Axiom
annotated source: has continuant part at all times that part exists
annotated property: editor note
annotated target: This is a binary version of a ternary time-indexed, instance level, relation. Unlike the rest of the temporalized relations which temporally quantify over existence of the subject of the relation, this relation temporally quantifies over the existence of the object of the relation. The relation is provided tentatively, to assess whether the GO needs such a relation. It is inverse of 'part of continuant at all times'
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000600

entity
type: Class
subclass of: Restriction
BFO OWL specification label: entity
BFO CLIF specification label: Entity
example of usage: Julius Caesar
example of usage: Verdi’s Requiem
example of usage: the Second World War
example of usage: your body mass index
editor note: BFO 2 Reference: In all areas of empirical inquiry we encounter general terms of two sorts. First are general terms which refer to universals or types:animaltuberculosissurgical procedurediseaseSecond, are general terms used to refer to groups of entities which instantiate a given universal but do not correspond to the extension of any subuniversal of that universal because there is nothing intrinsic to the entities in question by virtue of which they – and only they – are counted as belonging to the given group. Examples are: animal purchased by the Emperortuberculosis diagnosed on a Wednesdaysurgical procedure performed on a patient from Stockholmperson identified as candidate for clinical trial #2056-555person who is signatory of Form 656-PPVpainting by Leonardo da VinciSuch terms, which represent what are called ‘specializations’ in [81
editor note: Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf
elucidation: An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])

Axiom
annotated source: entity
annotated property: editor note
annotated target: Entity doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example Werner Ceusters 'portions of reality' include 4 sorts, entities (as BFO construes them), universals, configurations, and relations. It is an open question as to whether entities as construed in BFO will at some point also include these other portions of reality. See, for example, 'How to track absolutely everything' at http://www.referent-tracking.com/_RTU/papers/CeustersICbookRevised.pdf
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000004
comment: per discussion with Barry Smith

Axiom
annotated source: entity
annotated property: elucidation
annotated target: An entity is anything that exists or has existed or will exist. (axiom label in BFO2 Reference: [001-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/001-001

continuant
type: Class
subclass of: entity
disjoint with: occurrent
BFO OWL specification label: continuant
BFO CLIF specification label: Continuant
editor note: BFO 2 Reference: Continuant entities are entities which can be sliced to yield parts only along the spatial dimension, yielding for example the parts of your table which we call its legs, its top, its nails. ‘My desk stretches from the window to the door. It has spatial parts, and can be sliced (in space) in two. With respect to time, however, a thing is a continuant.’ [60, p. 240
editor note: Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants
elucidation: A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])
has associated axiom(nl): if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])
has associated axiom(nl): if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])
has associated axiom(nl): if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])
has associated axiom(fol): (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002]
has associated axiom(fol): (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001]
has associated axiom(fol): (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002]
has associated axiom(fol): (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002]

Axiom
annotated source: continuant
annotated property: editor note
annotated target: Continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. For example, in an expansion involving bringing in some of Ceuster's other portions of reality, questions are raised as to whether universals are continuants
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000007

Axiom
annotated source: continuant
annotated property: elucidation
annotated target: A continuant is an entity that persists, endures, or continues to exist through time while maintaining its identity. (axiom label in BFO2 Reference: [008-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/008-002

Axiom
annotated source: continuant
annotated property: has associated axiom(nl)
annotated target: if b is a continuant and if, for some t, c has_continuant_part b at t, then c is a continuant. (axiom label in BFO2 Reference: [126-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/126-001

Axiom
annotated source: continuant
annotated property: has associated axiom(nl)
annotated target: if b is a continuant and if, for some t, cis continuant_part of b at t, then c is a continuant. (axiom label in BFO2 Reference: [009-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/009-002

Axiom
annotated source: continuant
annotated property: has associated axiom(nl)
annotated target: if b is a material entity, then there is some temporal interval (referred to below as a one-dimensional temporal region) during which b exists. (axiom label in BFO2 Reference: [011-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/011-002

Axiom
annotated source: continuant
annotated property: has associated axiom(fol)
annotated target: (forall (x y) (if (and (Continuant x) (exists (t) (continuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [009-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/009-002

Axiom
annotated source: continuant
annotated property: has associated axiom(fol)
annotated target: (forall (x y) (if (and (Continuant x) (exists (t) (hasContinuantPartOfAt y x t))) (Continuant y))) // axiom label in BFO2 CLIF: [126-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/126-001

Axiom
annotated source: continuant
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Continuant x) (Entity x))) // axiom label in BFO2 CLIF: [008-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/008-002

Axiom
annotated source: continuant
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Material Entity x) (exists (t) (and (TemporalRegion t) (existsAt x t))))) // axiom label in BFO2 CLIF: [011-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/011-002

occurrent
type: Class
subclass of: entity
BFO OWL specification label: occurrent
BFO CLIF specification label: Occurrent
editor note: BFO 2 Reference: every occurrent that is not a temporal or spatiotemporal region is s-dependent on some independent continuant that is not a spatial region
editor note: BFO 2 Reference: s-dependence obtains between every process and its participants in the sense that, as a matter of necessity, this process could not have existed unless these or those participants existed also. A process may have a succession of participants at different phases of its unfolding. Thus there may be different players on the field at different times during the course of a football game; but the process which is the entire game s-depends_on all of these players nonetheless. Some temporal parts of this process will s-depend_on on only some of the players.
editor note: Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process.
editor note: Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame.
elucidation: An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])
has associated axiom(nl): Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])
has associated axiom(nl): b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])
has associated axiom(fol): (forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001]
has associated axiom(fol): (forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001]

Axiom
annotated source: occurrent
annotated property: editor note
annotated target: Occurrent doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the sum of a process and the process boundary of another process.
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000006
comment: per discussion with Barry Smith

Axiom
annotated source: occurrent
annotated property: editor note
annotated target: Simons uses different terminology for relations of occurrents to regions: Denote the spatio-temporal location of a given occurrent e by 'spn[e]' and call this region its span. We may say an occurrent is at its span, in any larger region, and covers any smaller region. Now suppose we have fixed a frame of reference so that we can speak not merely of spatio-temporal but also of spatial regions (places) and temporal regions (times). The spread of an occurrent, (relative to a frame of reference) is the space it exactly occupies, and its spell is likewise the time it exactly occupies. We write 'spr[e]' and `spl[e]' respectively for the spread and spell of e, omitting mention of the frame.
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000012

Axiom
annotated source: occurrent
annotated property: elucidation
annotated target: An occurrent is an entity that unfolds itself in time or it is the instantaneous boundary of such an entity (for example a beginning or an ending) or it is a temporal or spatiotemporal region which such an entity occupies_temporal_region or occupies_spatiotemporal_region. (axiom label in BFO2 Reference: [077-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/077-002

Axiom
annotated source: occurrent
annotated property: has associated axiom(nl)
annotated target: Every occurrent occupies_spatiotemporal_region some spatiotemporal region. (axiom label in BFO2 Reference: [108-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/108-001

Axiom
annotated source: occurrent
annotated property: has associated axiom(nl)
annotated target: b is an occurrent entity iff b is an entity that has temporal parts. (axiom label in BFO2 Reference: [079-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/079-001

Axiom
annotated source: occurrent
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Occurrent x) (exists (r) (and (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion x r))))) // axiom label in BFO2 CLIF: [108-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/108-001

Axiom
annotated source: occurrent
annotated property: has associated axiom(fol)
annotated target: (forall (x) (iff (Occurrent x) (and (Entity x) (exists (y) (temporalPartOf y x))))) // axiom label in BFO2 CLIF: [079-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/079-001

independent continuant
type: Class
subclass of: continuant
subclass of: Restriction
BFO OWL specification label: ic
BFO CLIF specification label: IndependentContinuant
example of usage: a chair
example of usage: a heart
example of usage: a leg
example of usage: a molecule
example of usage: a spatial region
example of usage: an atom
example of usage: an orchestra.
example of usage: an organism
example of usage: the bottom right portion of a human torso
example of usage: the interior of your mouth
definition: b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])
has associated axiom(nl): For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])
has associated axiom(nl): For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])
has associated axiom(fol): (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001]
has associated axiom(fol): (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002]
has associated axiom(fol): (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002]

Axiom
annotated source: independent continuant
annotated property: definition
annotated target: b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/017-002

Axiom
annotated source: independent continuant
annotated property: has associated axiom(nl)
annotated target: For any independent continuant b and any time t there is some spatial region r such that b is located_in r at t. (axiom label in BFO2 Reference: [134-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/134-001

Axiom
annotated source: independent continuant
annotated property: has associated axiom(nl)
annotated target: For every independent continuant b and time t during the region of time spanned by its life, there are entities which s-depends_on b during t. (axiom label in BFO2 Reference: [018-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/018-002

Axiom
annotated source: independent continuant
annotated property: has associated axiom(fol)
annotated target: (forall (x t) (if (IndependentContinuant x) (exists (r) (and (SpatialRegion r) (locatedInAt x r t))))) // axiom label in BFO2 CLIF: [134-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/134-001

Axiom
annotated source: independent continuant
annotated property: has associated axiom(fol)
annotated target: (forall (x t) (if (and (IndependentContinuant x) (existsAt x t)) (exists (y) (and (Entity y) (specificallyDependsOnAt y x t))))) // axiom label in BFO2 CLIF: [018-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/018-002

Axiom
annotated source: independent continuant
annotated property: has associated axiom(fol)
annotated target: (iff (IndependentContinuant a) (and (Continuant a) (not (exists (b t) (specificallyDependsOnAt a b t))))) // axiom label in BFO2 CLIF: [017-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/017-002

spatial region
type: Class
subclass of: immaterial entity
subclass of: Restriction
BFO OWL specification label: s-region
BFO CLIF specification label: SpatialRegion
editor note: BFO 2 Reference: Spatial regions do not participate in processes.
editor note: Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional.
elucidation: A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001])
has associated axiom(nl): All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001])
has associated axiom(fol): (forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001]
has associated axiom(fol): (forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001]

Restriction
on property: occupies spatial region at some time
has self: true

Restriction
on property: has spatial occupant at some time
has self: true

Axiom
annotated source: spatial region
annotated property: editor note
annotated target: Spatial region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the union of a spatial point and a spatial line that doesn't overlap the point, or two spatial lines that intersect at a single point. In both cases the resultant spatial region is neither 0-dimensional, 1-dimensional, 2-dimensional, or 3-dimensional.
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000002
comment: per discussion with Barry Smith

Axiom
annotated source: spatial region
annotated property: elucidation
annotated target: A spatial region is a continuant entity that is a continuant_part_of spaceR as defined relative to some frame R. (axiom label in BFO2 Reference: [035-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/035-001

Axiom
annotated source: spatial region
annotated property: has associated axiom(nl)
annotated target: All continuant parts of spatial regions are spatial regions. (axiom label in BFO2 Reference: [036-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/036-001

Axiom
annotated source: spatial region
annotated property: has associated axiom(fol)
annotated target: (forall (x y t) (if (and (SpatialRegion x) (continuantPartOfAt y x t)) (SpatialRegion y))) // axiom label in BFO2 CLIF: [036-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/036-001

Axiom
annotated source: spatial region
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (SpatialRegion x) (Continuant x))) // axiom label in BFO2 CLIF: [035-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/035-001

temporal region
type: Class
subclass of: occurrent
subclass of: Restriction
BFO OWL specification label: t-region
BFO CLIF specification label: TemporalRegion
editor note: Temporal region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn't overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional
elucidation: A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001])
has associated axiom(nl): All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001])
has associated axiom(nl): Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002])
has associated axiom(fol): (forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002]
has associated axiom(fol): (forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001]
has associated axiom(fol): (forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001]

Restriction
on property: occupies temporal region
has self: true

Restriction
on property: has temporal occupant
has self: true

Axiom
annotated source: temporal region
annotated property: editor note
annotated target: Temporal region doesn't have a closure axiom because the subclasses don't exhaust all possibilites. An example would be the mereological sum of a temporal instant and a temporal interval that doesn't overlap the instant. In this case the resultant temporal region is neither 0-dimensional nor 1-dimensional
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000003
comment: per discussion with Barry Smith

Axiom
annotated source: temporal region
annotated property: elucidation
annotated target: A temporal region is an occurrent entity that is part of time as defined relative to some reference frame. (axiom label in BFO2 Reference: [100-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/100-001

Axiom
annotated source: temporal region
annotated property: has associated axiom(nl)
annotated target: All parts of temporal regions are temporal regions. (axiom label in BFO2 Reference: [101-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/101-001

Axiom
annotated source: temporal region
annotated property: has associated axiom(nl)
annotated target: Every temporal region t is such that t occupies_temporal_region t. (axiom label in BFO2 Reference: [119-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/119-002

Axiom
annotated source: temporal region
annotated property: has associated axiom(fol)
annotated target: (forall (r) (if (TemporalRegion r) (occupiesTemporalRegion r r))) // axiom label in BFO2 CLIF: [119-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/119-002

Axiom
annotated source: temporal region
annotated property: has associated axiom(fol)
annotated target: (forall (x y) (if (and (TemporalRegion x) (occurrentPartOf y x)) (TemporalRegion y))) // axiom label in BFO2 CLIF: [101-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/101-001

Axiom
annotated source: temporal region
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (TemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [100-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/100-001

two-dimensional spatial region
type: Class
subclass of: spatial region
subclass of: Restriction
BFO OWL specification label: 2d-s-region
BFO CLIF specification label: TwoDimensionalSpatialRegion
example of usage: an infinitely thin plane in space.
example of usage: the surface of a sphere-shaped part of space
elucidation: A two-dimensional spatial region is a spatial region that is of two dimensions. (axiom label in BFO2 Reference: [039-001])
has associated axiom(fol): (forall (x) (if (TwoDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [039-001]

Axiom
annotated source: two-dimensional spatial region
annotated property: elucidation
annotated target: A two-dimensional spatial region is a spatial region that is of two dimensions. (axiom label in BFO2 Reference: [039-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/039-001

Axiom
annotated source: two-dimensional spatial region
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (TwoDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [039-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/039-001

spatiotemporal region
type: Class
subclass of: occurrent
subclass of: Restriction
subclass of: Restriction
  on property: projects onto temporal region
  some values from: temporal region
BFO OWL specification label: st-region
BFO CLIF specification label: SpatiotemporalRegion
example of usage: the spatiotemporal region occupied by a human life
example of usage: the spatiotemporal region occupied by a process of cellular meiosis.
example of usage: the spatiotemporal region occupied by the development of a cancer tumor
elucidation: A spatiotemporal region is an occurrent entity that is part of spacetime. (axiom label in BFO2 Reference: [095-001])
has associated axiom(nl): All parts of spatiotemporal regions are spatiotemporal regions. (axiom label in BFO2 Reference: [096-001])
has associated axiom(nl): Each spatiotemporal region at any time t projects_onto some spatial region at t. (axiom label in BFO2 Reference: [099-001])
has associated axiom(nl): Each spatiotemporal region projects_onto some temporal region. (axiom label in BFO2 Reference: [098-001])
has associated axiom(nl): Every spatiotemporal region occupies_spatiotemporal_region itself.
has associated axiom(nl): Every spatiotemporal region s is such that s occupies_spatiotemporal_region s. (axiom label in BFO2 Reference: [107-002])
has associated axiom(fol): (forall (r) (if (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion r r))) // axiom label in BFO2 CLIF: [107-002]
has associated axiom(fol): (forall (x t) (if (SpatioTemporalRegion x) (exists (y) (and (SpatialRegion y) (spatiallyProjectsOntoAt x y t))))) // axiom label in BFO2 CLIF: [099-001]
has associated axiom(fol): (forall (x y) (if (and (SpatioTemporalRegion x) (occurrentPartOf y x)) (SpatioTemporalRegion y))) // axiom label in BFO2 CLIF: [096-001]
has associated axiom(fol): (forall (x) (if (SpatioTemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [095-001]
has associated axiom(fol): (forall (x) (if (SpatioTemporalRegion x) (exists (y) (and (TemporalRegion y) (temporallyProjectsOnto x y))))) // axiom label in BFO2 CLIF: [098-001]

Restriction
on property: has spatiotemporal occupant
has self: true

Restriction
on property: occupies spatiotemporal region
has self: true

Axiom
annotated source: spatiotemporal region
annotated property: elucidation
annotated target: A spatiotemporal region is an occurrent entity that is part of spacetime. (axiom label in BFO2 Reference: [095-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/095-001

Axiom
annotated source: spatiotemporal region
annotated property: has associated axiom(nl)
annotated target: All parts of spatiotemporal regions are spatiotemporal regions. (axiom label in BFO2 Reference: [096-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/096-001

Axiom
annotated source: spatiotemporal region
annotated property: has associated axiom(nl)
annotated target: Each spatiotemporal region at any time t projects_onto some spatial region at t. (axiom label in BFO2 Reference: [099-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/099-001

Axiom
annotated source: spatiotemporal region
annotated property: has associated axiom(nl)
annotated target: Each spatiotemporal region projects_onto some temporal region. (axiom label in BFO2 Reference: [098-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/098-001

Axiom
annotated source: spatiotemporal region
annotated property: has associated axiom(nl)
annotated target: Every spatiotemporal region s is such that s occupies_spatiotemporal_region s. (axiom label in BFO2 Reference: [107-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/107-002

Axiom
annotated source: spatiotemporal region
annotated property: has associated axiom(fol)
annotated target: (forall (r) (if (SpatioTemporalRegion r) (occupiesSpatioTemporalRegion r r))) // axiom label in BFO2 CLIF: [107-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/107-002

Axiom
annotated source: spatiotemporal region
annotated property: has associated axiom(fol)
annotated target: (forall (x t) (if (SpatioTemporalRegion x) (exists (y) (and (SpatialRegion y) (spatiallyProjectsOntoAt x y t))))) // axiom label in BFO2 CLIF: [099-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/099-001

Axiom
annotated source: spatiotemporal region
annotated property: has associated axiom(fol)
annotated target: (forall (x y) (if (and (SpatioTemporalRegion x) (occurrentPartOf y x)) (SpatioTemporalRegion y))) // axiom label in BFO2 CLIF: [096-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/096-001

Axiom
annotated source: spatiotemporal region
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (SpatioTemporalRegion x) (Occurrent x))) // axiom label in BFO2 CLIF: [095-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/095-001

Axiom
annotated source: spatiotemporal region
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (SpatioTemporalRegion x) (exists (y) (and (TemporalRegion y) (temporallyProjectsOnto x y))))) // axiom label in BFO2 CLIF: [098-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/098-001

process
type: Class
subclass of: occurrent
subclass of: Restriction
  on property: specifically depends on at some time
  some values from: material entity
BFO OWL specification label: process
BFO CLIF specification label: Process
example of usage: a process of cell-division, \ a beating of the heart
example of usage: a process of meiosis
example of usage: a process of sleeping
example of usage: the course of a disease
example of usage: the flight of a bird
example of usage: the life of an organism
example of usage: your process of aging.
definition: p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])
editor note: BFO 2 Reference: The realm of occurrents is less pervasively marked by the presence of natural units than is the case in the realm of independent continuants. Thus there is here no counterpart of ‘object’. In BFO 1.0 ‘process’ served as such a counterpart. In BFO 2.0 ‘process’ is, rather, the occurrent counterpart of ‘material entity’. Those natural – as contrasted with engineered, which here means: deliberately executed – units which do exist in the realm of occurrents are typically either parasitic on the existence of natural units on the continuant side, or they are fiat in nature. Thus we can count lives; we can count football games; we can count chemical reactions performed in experiments or in chemical manufacturing. We cannot count the processes taking place, for instance, in an episode of insect mating behavior.Even where natural units are identifiable, for example cycles in a cyclical process such as the beating of a heart or an organism’s sleep/wake cycle, the processes in question form a sequence with no discontinuities (temporal gaps) of the sort that we find for instance where billiard balls or zebrafish or planets are separated by clear spatial gaps. Lives of organisms are process units, but they too unfold in a continuous series from other, prior processes such as fertilization, and they unfold in turn in continuous series of post-life processes such as post-mortem decay. Clear examples of boundaries of processes are almost always of the fiat sort (midnight, a time of death as declared in an operating theater or on a death certificate, the initiation of a state of war)
has associated axiom(fol): (iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003]

Axiom
annotated source: process
annotated property: definition
annotated target: p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/083-003

Axiom
annotated source: process
annotated property: has associated axiom(fol)
annotated target: (iff (Process a) (and (Occurrent a) (exists (b) (properTemporalPartOf b a)) (exists (c t) (and (MaterialEntity c) (specificallyDependsOnAt a c t))))) // axiom label in BFO2 CLIF: [083-003]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/083-003

disposition
type: Class
subclass of: realizable entity
subclass of: Restriction
disjoint with: role
BFO OWL specification label: disposition
BFO CLIF specification label: Disposition
example of usage: an atom of element X has the disposition to decay to an atom of element Y
example of usage: certain people have a predisposition to colon cancer
example of usage: children are innately disposed to categorize objects in certain ways.
example of usage: the cell wall is disposed to filter chemicals in endocytosis and exocytosis
editor note: BFO 2 Reference: Dispositions exist along a strength continuum. Weaker forms of disposition are realized in only a fraction of triggering cases. These forms occur in a significant number of cases of a similar type.
elucidation: b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])
has associated axiom(nl): If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])
has associated axiom(fol): (forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002]
has associated axiom(fol): (forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002]

Axiom
annotated source: disposition
annotated property: elucidation
annotated target: b is a disposition means: b is a realizable entity & b’s bearer is some material entity & b is such that if it ceases to exist, then its bearer is physically changed, & b’s realization occurs when and because this bearer is in some special physical circumstances, & this realization occurs in virtue of the bearer’s physical make-up. (axiom label in BFO2 Reference: [062-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/062-002

Axiom
annotated source: disposition
annotated property: has associated axiom(nl)
annotated target: If b is a realizable entity then for all t at which b exists, b s-depends_on some material entity at t. (axiom label in BFO2 Reference: [063-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/063-002

Axiom
annotated source: disposition
annotated property: has associated axiom(fol)
annotated target: (forall (x t) (if (and (RealizableEntity x) (existsAt x t)) (exists (y) (and (MaterialEntity y) (specificallyDepends x y t))))) // axiom label in BFO2 CLIF: [063-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/063-002

Axiom
annotated source: disposition
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Disposition x) (and (RealizableEntity x) (exists (y) (and (MaterialEntity y) (bearerOfAt x y t)))))) // axiom label in BFO2 CLIF: [062-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/062-002

realizable entity
type: Class
subclass of: specifically dependent continuant
subclass of: Restriction
disjoint with: quality
BFO OWL specification label: realizable
BFO CLIF specification label: RealizableEntity
example of usage: the disposition of this piece of metal to conduct electricity.
example of usage: the disposition of your blood to coagulate
example of usage: the function of your reproductive organs
example of usage: the role of being a doctor
example of usage: the role of this boundary to delineate where Utah and Colorado meet
elucidation: To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])
has associated axiom(nl): All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])
has associated axiom(fol): (forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002]
has associated axiom(fol): (forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002]

Axiom
annotated source: realizable entity
annotated property: elucidation
annotated target: To say that b is a realizable entity is to say that b is a specifically dependent continuant that inheres in some independent continuant which is not a spatial region and is of a type instances of which are realized in processes of a correlated type. (axiom label in BFO2 Reference: [058-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/058-002

Axiom
annotated source: realizable entity
annotated property: has associated axiom(nl)
annotated target: All realizable dependent continuants have independent continuants that are not spatial regions as their bearers. (axiom label in BFO2 Reference: [060-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/060-002

Axiom
annotated source: realizable entity
annotated property: has associated axiom(fol)
annotated target: (forall (x t) (if (RealizableEntity x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (bearerOfAt y x t))))) // axiom label in BFO2 CLIF: [060-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/060-002

Axiom
annotated source: realizable entity
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (RealizableEntity x) (and (SpecificallyDependentContinuant x) (exists (y) (and (IndependentContinuant y) (not (SpatialRegion y)) (inheresIn x y)))))) // axiom label in BFO2 CLIF: [058-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/058-002

zero-dimensional spatial region
type: Class
subclass of: spatial region
subclass of: Restriction
BFO OWL specification label: 0d-s-region
BFO CLIF specification label: ZeroDimensionalSpatialRegion
elucidation: A zero-dimensional spatial region is a point in space. (axiom label in BFO2 Reference: [037-001])
has associated axiom(fol): (forall (x) (if (ZeroDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [037-001]

Axiom
annotated source: zero-dimensional spatial region
annotated property: elucidation
annotated target: A zero-dimensional spatial region is a point in space. (axiom label in BFO2 Reference: [037-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/037-001

Axiom
annotated source: zero-dimensional spatial region
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (ZeroDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [037-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/037-001

quality
type: Class
subclass of: specifically dependent continuant
subclass of: Restriction
BFO OWL specification label: quality
BFO CLIF specification label: Quality
example of usage: the ambient temperature of this portion of air
example of usage: the color of a tomato
example of usage: the length of the circumference of your waist
example of usage: the mass of this piece of gold.
example of usage: the shape of your nose
example of usage: the shape of your nostril
elucidation: a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])
has associated axiom(nl): If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])
has associated axiom(fol): (forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001]
has associated axiom(fol): (forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001]

Axiom
annotated source: quality
annotated property: elucidation
annotated target: a quality is a specifically dependent continuant that, in contrast to roles and dispositions, does not require any further process in order to be realized. (axiom label in BFO2 Reference: [055-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/055-001

Axiom
annotated source: quality
annotated property: has associated axiom(nl)
annotated target: If an entity is a quality at any time that it exists, then it is a quality at every time that it exists. (axiom label in BFO2 Reference: [105-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/105-001

Axiom
annotated source: quality
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Quality x) (SpecificallyDependentContinuant x))) // axiom label in BFO2 CLIF: [055-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/055-001

Axiom
annotated source: quality
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (exists (t) (and (existsAt x t) (Quality x))) (forall (t_1) (if (existsAt x t_1) (Quality x))))) // axiom label in BFO2 CLIF: [105-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/105-001

specifically dependent continuant
type: Class
subclass of: continuant
subclass of: Restriction
BFO OWL specification label: sdc
BFO CLIF specification label: SpecificallyDependentContinuant
example of usage: Reciprocal specifically dependent continuants: the function of this key to open this lock and the mutually dependent disposition of this lock: to be opened by this key
example of usage: of one-sided specifically dependent continuants: the mass of this tomato
example of usage: of relational dependent continuants (multiple bearers): John’s love for Mary, the ownership relation between John and this statue, the relation of authority between John and his subordinates.
example of usage: the disposition of this fish to decay
example of usage: the function of this heart: to pump blood
example of usage: the mutual dependence of proton donors and acceptors in chemical reactions [79
example of usage: the mutual dependence of the role predator and the role prey as played by two organisms in a given interaction
example of usage: the pink color of a medium rare piece of grilled filet mignon at its center
example of usage: the role of being a doctor
example of usage: the shape of this hole.
example of usage: the smell of this portion of mozzarella
definition: b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n > 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i < j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004])
definition: b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])
editor note: Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc.
has associated axiom(fol): (iff (RelationalSpecificallyDependentContinuant a) (and (SpecificallyDependentContinuant a) (forall (t) (exists (b c) (and (not (SpatialRegion b)) (not (SpatialRegion c)) (not (= b c)) (not (exists (d) (and (continuantPartOfAt d b t) (continuantPartOfAt d c t)))) (specificallyDependsOnAt a b t) (specificallyDependsOnAt a c t)))))) // axiom label in BFO2 CLIF: [131-004]
has associated axiom(fol): (iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003]

Axiom
annotated source: specifically dependent continuant
annotated property: definition
annotated target: b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n > 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i < j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/131-004

Axiom
annotated source: specifically dependent continuant
annotated property: definition
annotated target: b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/050-003

Axiom
annotated source: specifically dependent continuant
annotated property: editor note
annotated target: Specifically dependent continuant doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. We're not sure what else will develop here, but for example there are questions such as what are promises, obligation, etc.
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000005
comment: per discussion with Barry Smith

Axiom
annotated source: specifically dependent continuant
annotated property: has associated axiom(fol)
annotated target: (iff (RelationalSpecificallyDependentContinuant a) (and (SpecificallyDependentContinuant a) (forall (t) (exists (b c) (and (not (SpatialRegion b)) (not (SpatialRegion c)) (not (= b c)) (not (exists (d) (and (continuantPartOfAt d b t) (continuantPartOfAt d c t)))) (specificallyDependsOnAt a b t) (specificallyDependsOnAt a c t)))))) // axiom label in BFO2 CLIF: [131-004]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/131-004

Axiom
annotated source: specifically dependent continuant
annotated property: has associated axiom(fol)
annotated target: (iff (SpecificallyDependentContinuant a) (and (Continuant a) (forall (t) (if (existsAt a t) (exists (b) (and (IndependentContinuant b) (not (SpatialRegion b)) (specificallyDependsOnAt a b t))))))) // axiom label in BFO2 CLIF: [050-003]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/050-003

role
type: Class
subclass of: realizable entity
subclass of: Restriction
BFO OWL specification label: role
BFO CLIF specification label: Role
example of usage: John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married.
example of usage: the priest role
example of usage: the role of a boundary to demarcate two neighboring administrative territories
example of usage: the role of a building in serving as a military target
example of usage: the role of a stone in marking a property boundary
example of usage: the role of subject in a clinical trial
example of usage: the student role
editor note: BFO 2 Reference: One major family of examples of non-rigid universals involves roles, and ontologies developed for corresponding administrative purposes may consist entirely of representatives of entities of this sort. Thus ‘professor’, defined as follows,b instance_of professor at t =Def. there is some c, c instance_of professor role & c inheres_in b at t.denotes a non-rigid universal and so also do ‘nurse’, ‘student’, ‘colonel’, ‘taxpayer’, and so forth. (These terms are all, in the jargon of philosophy, phase sortals.) By using role terms in definitions, we can create a BFO conformant treatment of such entities drawing on the fact that, while an instance of professor may be simultaneously an instance of trade union member, no instance of the type professor role is also (at any time) an instance of the type trade union member role (any more than any instance of the type color is at any time an instance of the type length).If an ontology of employment positions should be defined in terms of roles following the above pattern, this enables the ontology to do justice to the fact that individuals instantiate the corresponding universals – professor, sergeant, nurse – only during certain phases in their lives.
elucidation: b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])
has associated axiom(fol): (forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001]

Axiom
annotated source: role
annotated property: elucidation
annotated target: b is a role means: b is a realizable entity & b exists because there is some single bearer that is in some special physical, social, or institutional set of circumstances in which this bearer does not have to be& b is not such that, if it ceases to exist, then the physical make-up of the bearer is thereby changed. (axiom label in BFO2 Reference: [061-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/061-001

Axiom
annotated source: role
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Role x) (RealizableEntity x))) // axiom label in BFO2 CLIF: [061-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/061-001

fiat object
type: Class
subclass of: material entity
BFO OWL specification label: fiat-object
BFO CLIF specification label: FiatObjectPart
example of usage: or with divisions drawn by cognitive subjects for practical reasons, such as the division of a cake (before slicing) into (what will become) slices (and thus member parts of an object aggregate). However, this does not mean that fiat object parts are dependent for their existence on divisions or delineations effected by cognitive subjects. If, for example, it is correct to conceive geological layers of the Earth as fiat object parts of the Earth, then even though these layers were first delineated in recent times, still existed long before such delineation and what holds of these layers (for example that the oldest layers are also the lowest layers) did not begin to hold because of our acts of delineation.Treatment of material entity in BFOExamples viewed by some as problematic cases for the trichotomy of fiat object part, object, and object aggregate include: a mussel on (and attached to) a rock, a slime mold, a pizza, a cloud, a galaxy, a railway train with engine and multiple carriages, a clonal stand of quaking aspen, a bacterial community (biofilm), a broken femur. Note that, as Aristotle already clearly recognized, such problematic cases – which lie at or near the penumbra of instances defined by the categories in question – need not invalidate these categories. The existence of grey objects does not prove that there are not objects which are black and objects which are white; the existence of mules does not prove that there are not objects which are donkeys and objects which are horses. It does, however, show that the examples in question need to be addressed carefully in order to show how they can be fitted into the proposed scheme, for example by recognizing additional subdivisions [29
example of usage: the FMA:regional parts of an intact human body.
example of usage: the Western hemisphere of the Earth
example of usage: the division of the brain into regions
example of usage: the division of the planet into hemispheres
example of usage: the dorsal and ventral surfaces of the body
example of usage: the upper and lower lobes of the left lung
editor note: BFO 2 Reference: Most examples of fiat object parts are associated with theoretically drawn divisions
elucidation: b is a fiat object part = Def. b is a material entity which is such that for all times t, if b exists at t then there is some object c such that b proper continuant_part of c at t and c is demarcated from the remainder of c by a two-dimensional continuant fiat boundary. (axiom label in BFO2 Reference: [027-004])
has associated axiom(fol): (forall (x) (if (FiatObjectPart x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y) (and (Object y) (properContinuantPartOfAt x y t)))))))) // axiom label in BFO2 CLIF: [027-004]

Axiom
annotated source: fiat object
annotated property: elucidation
annotated target: b is a fiat object part = Def. b is a material entity which is such that for all times t, if b exists at t then there is some object c such that b proper continuant_part of c at t and c is demarcated from the remainder of c by a two-dimensional continuant fiat boundary. (axiom label in BFO2 Reference: [027-004])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/027-004

Axiom
annotated source: fiat object
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (FiatObjectPart x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y) (and (Object y) (properContinuantPartOfAt x y t)))))))) // axiom label in BFO2 CLIF: [027-004]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/027-004

one-dimensional spatial region
type: Class
subclass of: spatial region
subclass of: Restriction
BFO OWL specification label: 1d-s-region
BFO CLIF specification label: OneDimensionalSpatialRegion
example of usage: an edge of a cube-shaped portion of space.
elucidation: A one-dimensional spatial region is a line or aggregate of lines stretching from one point in space to another. (axiom label in BFO2 Reference: [038-001])
has associated axiom(fol): (forall (x) (if (OneDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [038-001]

Axiom
annotated source: one-dimensional spatial region
annotated property: elucidation
annotated target: A one-dimensional spatial region is a line or aggregate of lines stretching from one point in space to another. (axiom label in BFO2 Reference: [038-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/038-001

Axiom
annotated source: one-dimensional spatial region
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (OneDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [038-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/038-001

object aggregate
type: Class
subclass of: material entity
BFO OWL specification label: object-aggregate
BFO CLIF specification label: ObjectAggregate
example of usage: a collection of cells in a blood biobank.
example of usage: a swarm of bees is an aggregate of members who are linked together through natural bonds
example of usage: a symphony orchestra
example of usage: an organization is an aggregate whose member parts have roles of specific types (for example in a jazz band, a chess club, a football team)
example of usage: defined by fiat: the aggregate of members of an organization
example of usage: defined through physical attachment: the aggregate of atoms in a lump of granite
example of usage: defined through physical containment: the aggregate of molecules of carbon dioxide in a sealed container
example of usage: defined via attributive delimitations such as: the patients in this hospital
example of usage: the aggregate of bearings in a constant velocity axle joint
example of usage: the aggregate of blood cells in your body
example of usage: the nitrogen atoms in the atmosphere
example of usage: the restaurants in Palo Alto
example of usage: your collection of Meissen ceramic plates.
editor note: An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects
editor note: BFO 2 Reference: object aggregates may gain and lose parts while remaining numerically identical (one and the same individual) over time. This holds both for aggregates whose membership is determined naturally (the aggregate of cells in your body) and aggregates determined by fiat (a baseball team, a congressional committee).
definition source: ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, 'A Theory of Granular Partitions', in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158.
elucidation: b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004])
has associated axiom(fol): (forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004]

Axiom
annotated source: object aggregate
annotated property: editor note
annotated target: An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000011

Axiom
annotated source: object aggregate
annotated property: editor note
annotated target: An entity a is an object aggregate if and only if there is a mutually exhaustive and pairwise disjoint partition of a into objects
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000301

Axiom
annotated source: object aggregate
annotated property: definition source
annotated target: ISBN:978-3-938793-98-5pp124-158#Thomas Bittner and Barry Smith, 'A Theory of Granular Partitions', in K. Munn and B. Smith (eds.), Applied Ontology: An Introduction, Frankfurt/Lancaster: ontos, 2008, 125-158.
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000300

Axiom
annotated source: object aggregate
annotated property: elucidation
annotated target: b is an object aggregate means: b is a material entity consisting exactly of a plurality of objects as member_parts at all times at which b exists. (axiom label in BFO2 Reference: [025-004])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/025-004

Axiom
annotated source: object aggregate
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (ObjectAggregate x) (and (MaterialEntity x) (forall (t) (if (existsAt x t) (exists (y z) (and (Object y) (Object z) (memberPartOfAt y x t) (memberPartOfAt z x t) (not (= y z)))))) (not (exists (w t_1) (and (memberPartOfAt w x t_1) (not (Object w)))))))) // axiom label in BFO2 CLIF: [025-004]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/025-004

three-dimensional spatial region
type: Class
subclass of: spatial region
BFO OWL specification label: 3d-s-region
BFO CLIF specification label: ThreeDimensionalSpatialRegion
example of usage: a cube-shaped region of space
example of usage: a sphere-shaped region of space,
elucidation: A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001])
has associated axiom(fol): (forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001]

Axiom
annotated source: three-dimensional spatial region
annotated property: elucidation
annotated target: A three-dimensional spatial region is a spatial region that is of three dimensions. (axiom label in BFO2 Reference: [040-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/040-001

Axiom
annotated source: three-dimensional spatial region
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (ThreeDimensionalSpatialRegion x) (SpatialRegion x))) // axiom label in BFO2 CLIF: [040-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/040-001

site
type: Class
subclass of: immaterial entity
BFO OWL specification label: site
BFO CLIF specification label: Site
example of usage: Manhattan Canyon)
example of usage: a hole in the interior of a portion of cheese
example of usage: a rabbit hole
example of usage: an air traffic control region defined in the airspace above an airport
example of usage: the Grand Canyon
example of usage: the Piazza San Marco
example of usage: the cockpit of an aircraft
example of usage: the hold of a ship
example of usage: the interior of a kangaroo pouch
example of usage: the interior of the trunk of your car
example of usage: the interior of your bedroom
example of usage: the interior of your office
example of usage: the interior of your refrigerator
example of usage: the lumen of your gut
example of usage: your left nostril (a fiat part – the opening – of your left nasal cavity)
elucidation: b is a site means: b is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or it is a three-dimensional immaterial part thereof. (axiom label in BFO2 Reference: [034-002])
has associated axiom(fol): (forall (x) (if (Site x) (ImmaterialEntity x))) // axiom label in BFO2 CLIF: [034-002]

Axiom
annotated source: site
annotated property: elucidation
annotated target: b is a site means: b is a three-dimensional immaterial entity that is (partially or wholly) bounded by a material entity or it is a three-dimensional immaterial part thereof. (axiom label in BFO2 Reference: [034-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/034-002

Axiom
annotated source: site
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Site x) (ImmaterialEntity x))) // axiom label in BFO2 CLIF: [034-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/034-002

object
type: Class
subclass of: material entity
BFO OWL specification label: object
BFO CLIF specification label: Object
example of usage: atom
example of usage: cell
example of usage: cells and organisms
example of usage: engineered artifacts
example of usage: grain of sand
example of usage: molecule
example of usage: organelle
example of usage: organism
example of usage: planet
example of usage: solid portions of matter
example of usage: star
editor note: BFO 2 Reference: BFO rests on the presupposition that at multiple micro-, meso- and macroscopic scales reality exhibits certain stable, spatially separated or separable material units, combined or combinable into aggregates of various sorts (for example organisms into what are called ‘populations’). Such units play a central role in almost all domains of natural science from particle physics to cosmology. Many scientific laws govern the units in question, employing general terms (such as ‘molecule’ or ‘planet’) referring to the types and subtypes of units, and also to the types and subtypes of the processes through which such units develop and interact. The division of reality into such natural units is at the heart of biological science, as also is the fact that these units may form higher-level units (as cells form multicellular organisms) and that they may also form aggregates of units, for example as cells form portions of tissue and organs form families, herds, breeds, species, and so on. At the same time, the division of certain portions of reality into engineered units (manufactured artifacts) is the basis of modern industrial technology, which rests on the distributed mass production of engineered parts through division of labor and on their assembly into larger, compound units such as cars and laptops. The division of portions of reality into units is one starting point for the phenomenon of counting.
editor note: BFO 2 Reference: Each object is such that there are entities of which we can assert unproblematically that they lie in its interior, and other entities of which we can assert unproblematically that they lie in its exterior. This may not be so for entities lying at or near the boundary between the interior and exterior. This means that two objects – for example the two cells depicted in Figure 3 – may be such that there are material entities crossing their boundaries which belong determinately to neither cell. Something similar obtains in certain cases of conjoined twins (see below).
editor note: BFO 2 Reference: To say that b is causally unified means: b is a material entity which is such that its material parts are tied together in such a way that, in environments typical for entities of the type in question,if c, a continuant part of b that is in the interior of b at t, is larger than a certain threshold size (which will be determined differently from case to case, depending on factors such as porosity of external cover) and is moved in space to be at t at a location on the exterior of the spatial region that had been occupied by b at t, then either b’s other parts will be moved in coordinated fashion or b will be damaged (be affected, for example, by breakage or tearing) in the interval between t and t.causal changes in one part of b can have consequences for other parts of b without the mediation of any entity that lies on the exterior of b. Material entities with no proper material parts would satisfy these conditions trivially. Candidate examples of types of causal unity for material entities of more complex sorts are as follows (this is not intended to be an exhaustive list):CU1: Causal unity via physical coveringHere the parts in the interior of the unified entity are combined together causally through a common membrane or other physical covering\. The latter points outwards toward and may serve a protective function in relation to what lies on the exterior of the entity [13, 47
editor note: BFO 2 Reference: an object is a maximal causally unified material entity
editor note: BFO 2 Reference: ‘objects’ are sometimes referred to as ‘grains’ [74
elucidation: b is an object means: b is a material entity which manifests causal unity of one or other of the types CUn listed above & is of a type (a material universal) instances of which are maximal relative to this criterion of causal unity. (axiom label in BFO2 Reference: [024-001])

Axiom
annotated source: object
annotated property: elucidation
annotated target: b is an object means: b is a material entity which manifests causal unity of one or other of the types CUn listed above & is of a type (a material universal) instances of which are maximal relative to this criterion of causal unity. (axiom label in BFO2 Reference: [024-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/024-001

generically dependent continuant
type: Class
subclass of: continuant
subclass of: Restriction
BFO OWL specification label: gdc
BFO CLIF specification label: GenericallyDependentContinuant
example of usage: The entries in your database are patterns instantiated as quality instances in your hard drive. The database itself is an aggregate of such patterns. When you create the database you create a particular instance of the generically dependent continuant type database. Each entry in the database is an instance of the generically dependent continuant type IAO: information content entity.
example of usage: the pdf file on your laptop, the pdf file that is a copy thereof on my laptop
example of usage: the sequence of this protein molecule; the sequence that is a copy thereof in that protein molecule.
definition: b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])
has associated axiom(fol): (iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001]

Axiom
annotated source: generically dependent continuant
annotated property: definition
annotated target: b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/074-001

Axiom
annotated source: generically dependent continuant
annotated property: has associated axiom(fol)
annotated target: (iff (GenericallyDependentContinuant a) (and (Continuant a) (exists (b t) (genericallyDependsOnAt a b t)))) // axiom label in BFO2 CLIF: [074-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/074-001

function
type: Class
subclass of: disposition
BFO OWL specification label: function
BFO CLIF specification label: Function
example of usage: the function of a hammer to drive in nails
example of usage: the function of a heart pacemaker to regulate the beating of a heart through electricity
example of usage: the function of amylase in saliva to break down starch into sugar
editor note: BFO 2 Reference: In the past, we have distinguished two varieties of function, artifactual function and biological function. These are not asserted subtypes of BFO:function however, since the same function – for example: to pump, to transport – can exist both in artifacts and in biological entities. The asserted subtypes of function that would be needed in order to yield a separate monoheirarchy are not artifactual function, biological function, etc., but rather transporting function, pumping function, etc.
elucidation: A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])
has associated axiom(fol): (forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001]

Axiom
annotated source: function
annotated property: elucidation
annotated target: A function is a disposition that exists in virtue of the bearer’s physical make-up and this physical make-up is something the bearer possesses because it came into being, either through evolution (in the case of natural biological entities) or through intentional design (in the case of artifacts), in order to realize processes of a certain sort. (axiom label in BFO2 Reference: [064-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/064-001

Axiom
annotated source: function
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (Function x) (Disposition x))) // axiom label in BFO2 CLIF: [064-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/064-001

process boundary
type: Class
subclass of: occurrent
subclass of: Restriction
BFO OWL specification label: p-boundary
BFO CLIF specification label: ProcessBoundary
example of usage: the boundary between the 2nd and 3rd year of your life.
definition: p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])
has associated axiom(nl): Every process boundary occupies_temporal_region a zero-dimensional temporal region. (axiom label in BFO2 Reference: [085-002])
has associated axiom(fol): (forall (x) (if (ProcessBoundary x) (exists (y) (and (ZeroDimensionalTemporalRegion y) (occupiesTemporalRegion x y))))) // axiom label in BFO2 CLIF: [085-002]
has associated axiom(fol): (iff (ProcessBoundary a) (exists (p) (and (Process p) (temporalPartOf a p) (not (exists (b) (properTemporalPartOf b a)))))) // axiom label in BFO2 CLIF: [084-001]

Axiom
annotated source: process boundary
annotated property: definition
annotated target: p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/084-001

Axiom
annotated source: process boundary
annotated property: has associated axiom(nl)
annotated target: Every process boundary occupies_temporal_region a zero-dimensional temporal region. (axiom label in BFO2 Reference: [085-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/085-002

Axiom
annotated source: process boundary
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (ProcessBoundary x) (exists (y) (and (ZeroDimensionalTemporalRegion y) (occupiesTemporalRegion x y))))) // axiom label in BFO2 CLIF: [085-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/085-002

Axiom
annotated source: process boundary
annotated property: has associated axiom(fol)
annotated target: (iff (ProcessBoundary a) (exists (p) (and (Process p) (temporalPartOf a p) (not (exists (b) (properTemporalPartOf b a)))))) // axiom label in BFO2 CLIF: [084-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/084-001

one-dimensional temporal region
type: Class
subclass of: temporal region
disjoint with: zero-dimensional temporal region
BFO OWL specification label: 1d-t-region
BFO CLIF specification label: OneDimensionalTemporalRegion
example of usage: the temporal region during which a process occurs.
editor note: BFO 2 Reference: A temporal interval is a special kind of one-dimensional temporal region, namely one that is self-connected (is without gaps or breaks).
elucidation: A one-dimensional temporal region is a temporal region that is extended. (axiom label in BFO2 Reference: [103-001])
has associated axiom(fol): (forall (x) (if (OneDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [103-001]

Axiom
annotated source: one-dimensional temporal region
annotated property: elucidation
annotated target: A one-dimensional temporal region is a temporal region that is extended. (axiom label in BFO2 Reference: [103-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/103-001

Axiom
annotated source: one-dimensional temporal region
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (OneDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [103-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/103-001

material entity
type: Class
subclass of: independent continuant
subclass of: Restriction
  on property: occupies spatial region at some time
  all values from: three-dimensional spatial region
subclass of: Restriction
  on property: part of continuant at all times that whole exists
  all values from: material entity
disjoint with: immaterial entity
BFO OWL specification label: material
BFO CLIF specification label: MaterialEntity
example of usage: a flame
example of usage: a forest fire
example of usage: a human being
example of usage: a hurricane
example of usage: a photon
example of usage: a puff of smoke
example of usage: a sea wave
example of usage: a tornado
example of usage: an aggregate of human beings.
example of usage: an energy wave
example of usage: an epidemic
example of usage: the undetached arm of a human being
editor note: BFO 2 Reference: Material entities (continuants) can preserve their identity even while gaining and losing material parts. Continuants are contrasted with occurrents, which unfold themselves in successive temporal parts or phases [60
editor note: BFO 2 Reference: Object, Fiat Object Part and Object Aggregate are not intended to be exhaustive of Material Entity. Users are invited to propose new subcategories of Material Entity.
editor note: BFO 2 Reference: ‘Matter’ is intended to encompass both mass and energy (we will address the ontological treatment of portions of energy in a later version of BFO). A portion of matter is anything that includes elementary particles among its proper or improper parts: quarks and leptons, including electrons, as the smallest particles thus far discovered; baryons (including protons and neutrons) at a higher level of granularity; atoms and molecules at still higher levels, forming the cells, organs, organisms and other material entities studied by biologists, the portions of rock studied by geologists, the fossils studied by paleontologists, and so on.Material entities are three-dimensional entities (entities extended in three spatial dimensions), as contrasted with the processes in which they participate, which are four-dimensional entities (entities extended also along the dimension of time).According to the FMA, material entities may have immaterial entities as parts – including the entities identified below as sites; for example the interior (or ‘lumen’) of your small intestine is a part of your body. BFO 2.0 embodies a decision to follow the FMA here.
elucidation: A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])
has associated axiom(nl): Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])
has associated axiom(nl): every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])
has associated axiom(fol): (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002]
has associated axiom(fol): (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002]
has associated axiom(fol): (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002]

Axiom
annotated source: material entity
annotated property: elucidation
annotated target: A material entity is an independent continuant that has some portion of matter as proper or improper continuant part. (axiom label in BFO2 Reference: [019-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/019-002

Axiom
annotated source: material entity
annotated property: has associated axiom(nl)
annotated target: Every entity which has a material entity as continuant part is a material entity. (axiom label in BFO2 Reference: [020-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/020-002

Axiom
annotated source: material entity
annotated property: has associated axiom(nl)
annotated target: every entity of which a material entity is continuant part is also a material entity. (axiom label in BFO2 Reference: [021-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/021-002

Axiom
annotated source: material entity
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (MaterialEntity x) (IndependentContinuant x))) // axiom label in BFO2 CLIF: [019-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/019-002

Axiom
annotated source: material entity
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt x y t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [021-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/021-002

Axiom
annotated source: material entity
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (and (Entity x) (exists (y t) (and (MaterialEntity y) (continuantPartOfAt y x t)))) (MaterialEntity x))) // axiom label in BFO2 CLIF: [020-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/020-002

continuant fiat boundary
type: Class
subclass of: immaterial entity
subclass of: Restriction
BFO OWL specification label: cf-boundary
BFO CLIF specification label: ContinuantFiatBoundary
definition: b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])
editor note: BFO 2 Reference: In BFO 1.1 the assumption was made that the external surface of a material entity such as a cell could be treated as if it were a boundary in the mathematical sense. The new document propounds the view that when we talk about external surfaces of material objects in this way then we are talking about something fiat. To be dealt with in a future version: fiat boundaries at different levels of granularity.More generally, the focus in discussion of boundaries in BFO 2.0 is now on fiat boundaries, which means: boundaries for which there is no assumption that they coincide with physical discontinuities. The ontology of boundaries becomes more closely allied with the ontology of regions.
editor note: BFO 2 Reference: a continuant fiat boundary is a boundary of some material entity (for example: the plane separating the Northern and Southern hemispheres; the North Pole), or it is a boundary of some immaterial entity (for example of some portion of airspace). Three basic kinds of continuant fiat boundary can be distinguished (together with various combination kinds [29
editor note: Continuant fiat boundary doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the mereological sum of two-dimensional continuant fiat boundary and a one dimensional continuant fiat boundary that doesn't overlap it. The situation is analogous to temporal and spatial regions.
has associated axiom(nl): Every continuant fiat boundary is located at some spatial region at every time at which it exists
has associated axiom(fol): (iff (ContinuantFiatBoundary a) (and (ImmaterialEntity a) (exists (b) (and (or (ZeroDimensionalSpatialRegion b) (OneDimensionalSpatialRegion b) (TwoDimensionalSpatialRegion b)) (forall (t) (locatedInAt a b t)))) (not (exists (c t) (and (SpatialRegion c) (continuantPartOfAt c a t)))))) // axiom label in BFO2 CLIF: [029-001]

Axiom
annotated source: continuant fiat boundary
annotated property: definition
annotated target: b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/029-001

Axiom
annotated source: continuant fiat boundary
annotated property: editor note
annotated target: Continuant fiat boundary doesn't have a closure axiom because the subclasses don't necessarily exhaust all possibilites. An example would be the mereological sum of two-dimensional continuant fiat boundary and a one dimensional continuant fiat boundary that doesn't overlap it. The situation is analogous to temporal and spatial regions.
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000008

Axiom
annotated source: continuant fiat boundary
annotated property: has associated axiom(fol)
annotated target: (iff (ContinuantFiatBoundary a) (and (ImmaterialEntity a) (exists (b) (and (or (ZeroDimensionalSpatialRegion b) (OneDimensionalSpatialRegion b) (TwoDimensionalSpatialRegion b)) (forall (t) (locatedInAt a b t)))) (not (exists (c t) (and (SpatialRegion c) (continuantPartOfAt c a t)))))) // axiom label in BFO2 CLIF: [029-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/029-001

immaterial entity
type: Class
subclass of: independent continuant
subclass of: Restriction
BFO OWL specification label: immaterial
BFO CLIF specification label: ImmaterialEntity
editor note: BFO 2 Reference: Immaterial entities are divided into two subgroups:boundaries and sites, which bound, or are demarcated in relation, to material entities, and which can thus change location, shape and size and as their material hosts move or change shape or size (for example: your nasal passage; the hold of a ship; the boundary of Wales (which moves with the rotation of the Earth) [38, 7, 10

one-dimensional continuant fiat boundary
type: Class
subclass of: continuant fiat boundary
subclass of: Restriction
BFO OWL specification label: 1d-cf-boundary
BFO CLIF specification label: OneDimensionalContinuantFiatBoundary
example of usage: The Equator
example of usage: all geopolitical boundaries
example of usage: all lines of latitude and longitude
example of usage: the line separating the outer surface of the mucosa of the lower lip from the outer surface of the skin of the chin.
example of usage: the median sulcus of your tongue
elucidation: a one-dimensional continuant fiat boundary is a continuous fiat line whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [032-001])
has associated axiom(fol): (iff (OneDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (OneDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [032-001]

Axiom
annotated source: one-dimensional continuant fiat boundary
annotated property: elucidation
annotated target: a one-dimensional continuant fiat boundary is a continuous fiat line whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [032-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/032-001

Axiom
annotated source: one-dimensional continuant fiat boundary
annotated property: has associated axiom(fol)
annotated target: (iff (OneDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (OneDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [032-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/032-001

process profile
type: Class
equivalent class: Restriction
subclass of: process
subclass of: Restriction
disjoint with: history
BFO OWL specification label: process-profile
BFO CLIF specification label: ProcessProfile
example of usage: On a somewhat higher level of complexity are what we shall call rate process profiles, which are the targets of selective abstraction focused not on determinate quality magnitudes plotted over time, but rather on certain ratios between these magnitudes and elapsed times. A speed process profile, for example, is represented by a graph plotting against time the ratio of distance covered per unit of time. Since rates may change, and since such changes, too, may have rates of change, we have to deal here with a hierarchy of process profile universals at successive levels
example of usage: One important sub-family of rate process profiles is illustrated by the beat or frequency profiles of cyclical processes, illustrated by the 60 beats per minute beating process of John’s heart, or the 120 beats per minute drumming process involved in one of John’s performances in a rock band, and so on. Each such process includes what we shall call a beat process profile instance as part, a subtype of rate process profile in which the salient ratio is not distance covered but rather number of beat cycles per unit of time. Each beat process profile instance instantiates the determinable universal beat process profile. But it also instantiates multiple more specialized universals at lower levels of generality, selected from rate process profilebeat process profileregular beat process profile3 bpm beat process profile4 bpm beat process profileirregular beat process profileincreasing beat process profileand so on.In the case of a regular beat process profile, a rate can be assigned in the simplest possible fashion by dividing the number of cycles by the length of the temporal region occupied by the beating process profile as a whole. Irregular process profiles of this sort, for example as identified in the clinic, or in the readings on an aircraft instrument panel, are often of diagnostic significance.
example of usage: The simplest type of process profiles are what we shall call ‘quality process profiles’, which are the process profiles which serve as the foci of the sort of selective abstraction that is involved when measurements are made of changes in single qualities, as illustrated, for example, by process profiles of mass, temperature, aortic pressure, and so on.
definition: b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])
elucidation: b process_profile_of c holds when b proper_occurrent_part_of c& there is some proper_occurrent_part d of c which has no parts in common with b & is mutually dependent on b& is such that b, c and d occupy the same temporal region (axiom label in BFO2 Reference: [094-005])
has associated axiom(fol): (forall (x y) (if (processProfileOf x y) (and (properContinuantPartOf x y) (exists (z t) (and (properOccurrentPartOf z y) (TemporalRegion t) (occupiesSpatioTemporalRegion x t) (occupiesSpatioTemporalRegion y t) (occupiesSpatioTemporalRegion z t) (not (exists (w) (and (occurrentPartOf w x) (occurrentPartOf w z))))))))) // axiom label in BFO2 CLIF: [094-005]
has associated axiom(fol): (iff (ProcessProfile a) (exists (b) (and (Process b) (processProfileOf a b)))) // axiom label in BFO2 CLIF: [093-002]

Axiom
annotated source: process profile
annotated property: definition
annotated target: b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/093-002

Axiom
annotated source: process profile
annotated property: elucidation
annotated target: b process_profile_of c holds when b proper_occurrent_part_of c& there is some proper_occurrent_part d of c which has no parts in common with b & is mutually dependent on b& is such that b, c and d occupy the same temporal region (axiom label in BFO2 Reference: [094-005])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/094-005

Axiom
annotated source: process profile
annotated property: has associated axiom(fol)
annotated target: (forall (x y) (if (processProfileOf x y) (and (properContinuantPartOf x y) (exists (z t) (and (properOccurrentPartOf z y) (TemporalRegion t) (occupiesSpatioTemporalRegion x t) (occupiesSpatioTemporalRegion y t) (occupiesSpatioTemporalRegion z t) (not (exists (w) (and (occurrentPartOf w x) (occurrentPartOf w z))))))))) // axiom label in BFO2 CLIF: [094-005]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/094-005

Axiom
annotated source: process profile
annotated property: has associated axiom(fol)
annotated target: (iff (ProcessProfile a) (exists (b) (and (Process b) (processProfileOf a b)))) // axiom label in BFO2 CLIF: [093-002]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/093-002

relational quality
type: Class
equivalent class: Class
subclass of: quality
BFO OWL specification label: r-quality
BFO CLIF specification label: RelationalQuality
example of usage: John’s role of husband to Mary is dependent on Mary’s role of wife to John, and both are dependent on the object aggregate comprising John and Mary as member parts joined together through the relational quality of being married.
example of usage: a marriage bond, an instance of love, an obligation between one person and another.
definition: b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001])
has associated axiom(fol): (iff (RelationalQuality a) (exists (b c t) (and (IndependentContinuant b) (IndependentContinuant c) (qualityOfAt a b t) (qualityOfAt a c t)))) // axiom label in BFO2 CLIF: [057-001]

Class
intersection of: quality
intersection of: Restriction
  on property: inheres in at all times
  min qualified cardinality: 2
  on class: independent continuant

Axiom
annotated source: relational quality
annotated property: definition
annotated target: b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/057-001

Axiom
annotated source: relational quality
annotated property: has associated axiom(fol)
annotated target: (iff (RelationalQuality a) (exists (b c t) (and (IndependentContinuant b) (IndependentContinuant c) (qualityOfAt a b t) (qualityOfAt a c t)))) // axiom label in BFO2 CLIF: [057-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/057-001

two-dimensional continuant fiat boundary
type: Class
subclass of: continuant fiat boundary
BFO OWL specification label: 2d-cf-boundary
BFO CLIF specification label: TwoDimensionalContinuantFiatBoundary
elucidation: a two-dimensional continuant fiat boundary (surface) is a self-connected fiat surface whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [033-001])
has associated axiom(fol): (iff (TwoDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (TwoDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [033-001]

Axiom
annotated source: two-dimensional continuant fiat boundary
annotated property: elucidation
annotated target: a two-dimensional continuant fiat boundary (surface) is a self-connected fiat surface whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [033-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/033-001

Axiom
annotated source: two-dimensional continuant fiat boundary
annotated property: has associated axiom(fol)
annotated target: (iff (TwoDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (TwoDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [033-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/033-001

zero-dimensional continuant fiat boundary
type: Class
subclass of: continuant fiat boundary
subclass of: Restriction
BFO OWL specification label: 0d-cf-boundary
BFO CLIF specification label: ZeroDimensionalContinuantFiatBoundary
example of usage: the geographic North Pole
example of usage: the point of origin of some spatial coordinate system.
example of usage: the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet
editor note: zero dimension continuant fiat boundaries are not spatial points. Considering the example 'the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet' : There are many frames in which that point is zooming through many points in space. Whereas, no matter what the frame, the quadripoint is always in the same relation to the boundaries of Colorado, Utah, New Mexico, and Arizona.
elucidation: a zero-dimensional continuant fiat boundary is a fiat point whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [031-001])
has associated axiom(fol): (iff (ZeroDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (ZeroDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [031-001]

Axiom
annotated source: zero-dimensional continuant fiat boundary
annotated property: editor note
annotated target: zero dimension continuant fiat boundaries are not spatial points. Considering the example 'the quadripoint where the boundaries of Colorado, Utah, New Mexico, and Arizona meet' : There are many frames in which that point is zooming through many points in space. Whereas, no matter what the frame, the quadripoint is always in the same relation to the boundaries of Colorado, Utah, New Mexico, and Arizona.
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/0000001
comment: requested by Melanie Courtot

Axiom
annotated source: zero-dimensional continuant fiat boundary
annotated property: elucidation
annotated target: a zero-dimensional continuant fiat boundary is a fiat point whose location is defined in relation to some material entity. (axiom label in BFO2 Reference: [031-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/031-001

Axiom
annotated source: zero-dimensional continuant fiat boundary
annotated property: has associated axiom(fol)
annotated target: (iff (ZeroDimensionalContinuantFiatBoundary a) (and (ContinuantFiatBoundary a) (exists (b) (and (ZeroDimensionalSpatialRegion b) (forall (t) (locatedInAt a b t)))))) // axiom label in BFO2 CLIF: [031-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/031-001

zero-dimensional temporal region
type: Class
subclass of: temporal region
BFO OWL specification label: 0d-t-region
BFO CLIF specification label: ZeroDimensionalTemporalRegion
example of usage: a temporal region that is occupied by a process boundary
example of usage: right now
example of usage: the moment at which a child is born
example of usage: the moment at which a finger is detached in an industrial accident
example of usage: the moment of death.
alternative term: temporal instant.
elucidation: A zero-dimensional temporal region is a temporal region that is without extent. (axiom label in BFO2 Reference: [102-001])
has associated axiom(fol): (forall (x) (if (ZeroDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [102-001]

Axiom
annotated source: zero-dimensional temporal region
annotated property: elucidation
annotated target: A zero-dimensional temporal region is a temporal region that is without extent. (axiom label in BFO2 Reference: [102-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/102-001

Axiom
annotated source: zero-dimensional temporal region
annotated property: has associated axiom(fol)
annotated target: (forall (x) (if (ZeroDimensionalTemporalRegion x) (TemporalRegion x))) // axiom label in BFO2 CLIF: [102-001]
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/102-001

history
type: Class
subclass of: process
subclass of: Restriction
  on property: history of
  some values from: continuant
subclass of: Restriction
  on property: part of occurrent
  all values from: Class
    complement of: process profile
BFO OWL specification label: history
BFO CLIF specification label: History
elucidation: A history is a process that is the sum of the totality of processes taking place in the spatiotemporal region occupied by a material entity or site, including processes on the surface of the entity or within the cavities to which it serves as host. (axiom label in BFO2 Reference: [138-001])

Axiom
annotated source: history
annotated property: elucidation
annotated target: A history is a process that is the sum of the totality of processes taking place in the spatiotemporal region occupied by a material entity or site, including processes on the surface of the entity or within the cavities to which it serves as host. (axiom label in BFO2 Reference: [138-001])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/138-001

bacterial endocarditis
type: Class
subclass of: infective endocarditis
CVDO definition: An endocarditis caused by bacterial infection.

viral endocarditis
type: Class
subclass of: infective endocarditis
CVDO definition: An endocarditis caused by viral infection.

fungal endocarditis
type: Class
subclass of: infective endocarditis
CVDO definition: An endocarditis caused by fungal infection.

heart disorder
type: Class
equivalent class: Class
  intersection of: disorder
  intersection of: Restriction
    on property: located in at all times
    some values from: Heart
CVDO definition: A disorder located in the heart.

vascular disorder
type: Class
equivalent class: Class
  intersection of: disorder
  intersection of: Restriction
    on property: located in at all times
    some values from: Vascular tree
CVDO definition: A disorder always located in a blood vessel.

endocardium disorder
type: Class
equivalent class: Class
  intersection of: disorder
  intersection of: Restriction
    on property: located in at all times
    some values from: Endocardium
CVDO definition: A disorder always located in the endocardium.

pericardium disorder
type: Class
equivalent class: Class
  intersection of: disorder
  intersection of: Restriction
    on property: located in at all times
    some values from: Pericardium
CVDO definition: A disorder always located in the pericardium.
CVDO editor note: Since the pericardium is not a part of the heart according to FMA, pericardium disorder is not classified as a heart disorder.

infectious pericarditis
type: Class
subclass of: pericarditis
CVDO definition: A pericarditis caused by an infection.

bacterial pericarditis
type: Class
subclass of: infectious pericarditis
CVDO definition: A pericarditis caused by a bacterial infection.

viral pericarditis
type: Class
subclass of: infectious pericarditis
CVDO definition: A pericarditis caused by a viral infection.

fungal pericarditis
type: Class
subclass of: infectious pericarditis
CVDO definition: A pericarditis caused by a fungal infection.

protozoal pericarditis
type: Class
subclass of: infectious pericarditis

heart pathological process
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Heart
CVDO definition: A pathological process involving or occuring in the heart.

pericardium pathological process
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Pericardium
CVDO definition: A pathological process involving or occuring in the pericardium.

acute pericarditis
type: Class
equivalent class: Class
  intersection of: pericarditis
  intersection of: Restriction
    on property: realized in
    some values from: acute disease course
CVDO definition: A pericarditis that has an acute disease course.

chronic pericarditis
type: Class
equivalent class: Class
  intersection of: pericarditis
  intersection of: Restriction
    on property: realized in
    some values from: chronic disease course
CVDO definition: A pericarditis that has a chronic disease course.

atrioventricular block (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: atrioventricular block (process)
subclass of: Restriction
  on property: has material basis at all times
  some values from: impaired atrioventricular node

first degree atrioventricular block (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: first degree atrioventricular block (process)

Mobitz I second degree atrioventricular block (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: Mobitz I second degree atrioventricular block (process)

third degree atrioventricular block (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: third degree atrioventricular block (process)
has_exact_synonym: complete heart block

heart conduction disorder
type: Class
equivalent class: Class
  intersection of: disorder
  intersection of: Restriction
    on property: located in at all times
    some values from: Conducting tissue of heart
CVDO definition: A disorder always loacted in the conducting tissue of the heart.

impaired atrioventricular node
type: Class
subclass of: heart conduction disorder

impaired right branch of atrioventricular bundle
type: Class
subclass of: heart conduction disorder

bundle of Kent
type: Class
subclass of: atrioventricular accessory bundle

sinoatrial block (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: sinoatrial block (process)
subclass of: Restriction
  on property: has material basis at all times
  some values from: impaired sinoatrial node

Mobitz I second degree sinoatrial block (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: Mobitz I second degree sinoatrial block (process)
has_exact_synonym: Wenckebach block

Mobitz II second degree sinoatrial block (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: Mobitz II second degree sinoatrial block (process)
has_exact_synonym: sinus exit block

first degree sinoatrial block (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: first degree sinoatrial block (process)

third degree sinoatrial block (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: third degree sinoatrial block (process)

impaired sinoatrial node
type: Class
subclass of: heart conduction disorder

heart block (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: heart block (process)

impaired posterior division of left branch of atrioventricular bundle
type: Class
subclass of: heart conduction disorder

left posterior fascicular block (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: left posterior fascicular block (process)
subclass of: Restriction
  on property: has material basis at all times
  some values from: impaired posterior division of left branch of atrioventricular bundle

infra-hisian block (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: infra-hisian block (process)

left bundle branch block (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: left bundle branch block (process)
subclass of: Restriction
  on property: has material basis at all times
  some values from: Class
    intersection of: disorder
    intersection of: Restriction
      on property: has member part at all times
      some values from: impaired posterior division of left branch of atrioventricular bundle
    intersection of: Restriction
      on property: has member part at all times
      some values from: impaired anterior division of left branch of atrioventricular bundle

cardiac arrhythmia (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: cardiac arrhythmia (process)
CVDO definition: A heart conduction disease characterized by cardiac arrhythmia processes.
CVDO editor note: Usual medical language does not differentiate the disease and the corresponding pathological process for the different kinds of cardiac arrhythmias. CVDO distinguishes them explicitly with the suffix '(disease)' or '(process)'.

atrial fibrillation (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: atrial fibrillation (process)
disjoint union of: permanent atrial fibrillation
disjoint union of: paroxysmal atrial fibrillation
disjoint union of: persistent atrial fibrillation

atrial fibrillation (process)
type: Class
subclass of: supraventricular tachycardia (process)

atrial flutter (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: atrial flutter (process)

common atrial flutter (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: common atrial flutter (process)
has_exact_synonym: cavotricuspid isthmus dependant macroreentry tachycardia
has_exact_synonym: type I atrial flutter

cardiac atrium fibrosis
type: Class
subclass of: cardiac atrium pathological process
subclass of: Restriction
  on property: occurs in
  some values from: Cardiac atrium
CVDO definition: A pathological process of fibrosis of the cardiac atrium.

supraventricular tachycardia (process)
type: Class
subclass of: tachycardia (process)

bradycardia (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: bradycardia (process)

bradycardia (process)
type: Class
subclass of: cardiac arrhythmia (process)

premature atrial contraction (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: premature atrial contraction (process)

left anterior fascicle
type: Class
subclass of: Subdivision of conducting system of heart

heart valve disorder
type: Class
equivalent class: Class
  intersection of: disorder
  intersection of: Restriction
    on property: located in at all times
    some values from: Cardiac valve
definition: A disorder always located in a heart valve.

wandering pacemaker
type: Class
subclass of: heart conduction disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: cardiac arrhythmia (process)

tricuspid valve disease
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Class
    union of: Restriction
      on property: realized in
      some values from: Class
        intersection of: disease course
        intersection of: Restriction
    union of: Restriction
      on property: has material basis at all times
      some values from: tricuspid valve disorder
CVDO definition: A disease affecting the tricuspid valve of the heart.

myxomatous degenerated structure in a mitral valve leaflet
type: Class
subclass of: degenerated structure in a heart valve leaflet
subclass of: Restriction
  on property: located in at all times
  some values from: Mitral valve
definition: A degenerated structure in a mitral valve leaflet due to myxomatous proliferation.

heart pathological process involving a heart valve
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Heart
  intersection of: Restriction
    on property: has participant at all times
    some values from: Cardiac valve
CVDO definition: A heart pathological process that has a heart valve as a participant.
CVDO editor note: This class should not be confused with 'heart valve pathological process', which are pathological processes occurring in a heart valve, rather than pathological process having as participant a heart valve.

mitral valve leaflet displacement into the left atrium during left ventricular systole
type: Class
equivalent class: Class
  intersection of: heart valve leaflet displacement into a cardiac chamber
  intersection of: Restriction
    on property: part of occurrent
    some values from: left ventricular systole
  intersection of: Restriction
    on property: has participant at all times
    some values from: Mitral valve

tricuspid valve leaflet displacement into the right atrium during right ventricular systole
type: Class
equivalent class: Class
  intersection of: heart valve leaflet displacement into a cardiac chamber
  intersection of: Restriction
    on property: part of occurrent
    some values from: right ventricular systole
  intersection of: Restriction
    on property: has participant at all times
    some values from: Tricuspid valve

aortic valve leaflet displacement into the left ventricle during left ventricular diastole
type: Class
equivalent class: Class
  intersection of: heart valve leaflet displacement into a cardiac chamber
  intersection of: Restriction
    on property: part of occurrent
    some values from: left ventricular diastole
  intersection of: Restriction
    on property: has participant at all times
    some values from: Aortic valve

heart valve leaflet displacement into a cardiac chamber during ventricular systole
type: Class
equivalent class: Class
  intersection of: heart valve leaflet displacement into a cardiac chamber
  intersection of: Restriction
    on property: part of occurrent
    some values from: ventricular systole

mitral valve improper close during left ventricular systole
type: Class
equivalent class: Class
  intersection of: heart valve improper close
  intersection of: Restriction
    on property: part of occurrent
    some values from: left ventricular systole
  intersection of: Restriction
    on property: has participant at all times
    some values from: Mitral valve

retrograd blood flow through mitral valve during left ventricular systole
type: Class
subclass of: retrograd blood flow through a heart valve

retrograd blood flow through pulmonary valve during right ventricular diastole
type: Class
subclass of: retrograd blood flow through a heart valve

pulmonary valve improper close during right ventricular diastole
type: Class
equivalent class: Class
  intersection of: heart valve improper close
  intersection of: Restriction
    on property: part of occurrent
    some values from: right ventricular diastole
  intersection of: Restriction
    on property: has participant at all times
    some values from: Pulmonary valve

tricuspid valve improper close during right ventricular systole
type: Class
equivalent class: Class
  intersection of: heart valve improper close
  intersection of: Restriction
    on property: part of occurrent
    some values from: right ventricular systole
  intersection of: Restriction
    on property: has participant at all times
    some values from: Tricuspid valve

aortic valve improper close during left ventricular diastole
type: Class
equivalent class: Class
  intersection of: heart valve improper close
  intersection of: Restriction
    on property: part of occurrent
    some values from: left ventricular diastole
  intersection of: Restriction
    on property: has participant at all times
    some values from: Aortic valve

retrograd blood flow through tricuspid valve during right ventricular systole
type: Class
subclass of: retrograd blood flow through a heart valve

retrograd blood flow through aortic valve during left ventricular diastole
type: Class
subclass of: retrograd blood flow through a heart valve

disturbed anterograd blood flow through mitral valve during left ventricular diastole
type: Class
subclass of: disturbed anterograd blood flow through a heart valve

retrograd blood flow through a heart valve
type: Class
subclass of: cardiac blood circulation pathological process

disturbed anterograd blood flow through a heart valve
type: Class
subclass of: cardiac blood circulation pathological process

disturbed anterograd blood flow through tricuspid valve during right ventricular diastole
type: Class
subclass of: disturbed anterograd blood flow through a heart valve

disturbed anterograd blood flow through pulmonary valve during right ventricular systole
type: Class
subclass of: disturbed anterograd blood flow through a heart valve

disturbed anterograd blood flow through aortic valve during left ventricular systole
type: Class
subclass of: disturbed anterograd blood flow through a heart valve

heart valve stenosis
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: heart valve improper opening
  intersection of: Restriction
    on property: has material basis at all times
    some values from: heart valve disorder
CVDO definition: A disease in which some disorder of a heart valve prevents it from opening properly, occasioning disturbance in the anterograd blood flow through the valve.

impaired cardiac output
type: Class
subclass of: cardiac blood circulation pathological process

pressure
type: Class
subclass of: quality

blood pressure
type: Class
subclass of: pressure

highly pressured arterial blood flow
type: Class
subclass of: vascular blood circulation pathological process
CVDO definition: A pathological process of highly pressured aerterial blood flow.

heart valve insufficiency
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: heart valve improper close
  intersection of: Restriction
    on property: has material basis at all times
    some values from: heart valve disorder
CVDO definition: A disease in which an abnormal structure in a heart valve prevents it to close propertly, occasioning a retrograd blood flow through the valve.

heart valve improper close
type: Class
subclass of: pathological bodily process
subclass of: Restriction
  on property: occurs in
  some values from: Heart
subclass of: Restriction
  on property: has participant at all times
  some values from: Cardiac valve
CVDO definition: A pathological process of a heart valve closing improperly.

vein disorder
type: Class
equivalent class: Class
  intersection of: disorder
  intersection of: Restriction
    on property: located in at all times
    some values from: Venous tree organ
CVDO definition: A disorder always located in a vein.

vascular pathological process
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Vascular tree
subclass of: pathological bodily process
CVDO definition: A pathological process involving or occuring in a blood vessel.

thrombosis
type: Class
subclass of: pathological bodily process
subclass of: Restriction
  on property: occurs in
  some values from: Vascular tree
CVDO definition: A pathological process of formation of a blood clot inside a blood vessel, obstructing the flow of blood.

deep vein thrombosis
type: Class
subclass of: thrombosis
CVDO definition: A thrombosis occurring in a deep vein.

artery hardening
type: Class
subclass of: pathological bodily process
subclass of: Restriction
  on property: occurs in
  some values from: Arterial tree organ
CVDO definition: A pathological process of an artery hardening.

atheromous plaque formation in artery
type: Class
subclass of: pathological bodily process
subclass of: Restriction
  on property: occurs in
  some values from: Artery
CVDO definition: A pathological process of formation of atheromous plaques in an artery.

embolism
type: Class
subclass of: pathological bodily process
subclass of: Restriction
  on property: occurs in
  some values from: Vascular tree
subclass of: Restriction
  on property: has participant at all times
  some values from: embolus
CVDO definition: A pathological process of lodging of an embolus in a blood vessel.

aneurysm (disorder)
type: Class
subclass of: disorder
subclass of: Restriction
  on property: located in at all times
  some values from: Vascular tree
CVDO definition: A disorder of localized, blood-filled balloon-like bulge in the wall of a blood vessel.

ischemic disease
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: ischemia

compression disease
type: Class
subclass of: vascular disease

permanent atrial fibrillation
type: Class
subclass of: atrial fibrillation (disease)
subclass of: Restriction
  on property: realized in
  some values from: chronic disease course
CVDO definition: An atrial fibrillation disease that is characterized by an atrial fibrillation episode longer than 7 days which does not terminate by cardioversion.

right ventricular myocardium dilatation
type: Class
equivalent class: Class
  intersection of: ventricular myocardium dilatation
  intersection of: Restriction
    on property: occurs in
    some values from: Myocardium of right ventricle
CVDO definition: A pathological process of dilatation of the myocardium of a right cardiac ventricle.

aneurysm rupture
type: Class
subclass of: pathological bodily process
subclass of: Restriction
  on property: occurs in
  some values from: Vascular tree
subclass of: Restriction
  on property: has participant at all times
  some values from: aneurysm (disorder)
CVDO definition: A pathological process of an aneurysm rupturing.

myocardium disorder
type: Class
equivalent class: Class
  intersection of: disorder
  intersection of: Restriction
    on property: located in at all times
    some values from: Myocardium
CVDO definition: A disorder always located in the mycoardium.

Tako Tsubo cardiomyopathy
type: Class
subclass of: cardiomyopathy (1995 definition)
subclass of: Restriction
  on property: realized in
  some values from: transient disease course
CVDO definition: A cardiomyopathy whose etiological process includes a stressful or emotional situation, characterized by transient ventricular apical wall motion abnormalities (ballooning).
CVDO editor note: Tako-Tsubo cardiomyopathy is not a dilated cardiomyopathy in Elliott et al.'s (2008) classification.

left ventricular noncompaction
type: Class
subclass of: cardiomyopathy (2008 definition)
CVDO definition: "A cardiomyopathy characterized by prominent left ventricular trabeculae and deep inter-trabecular recesses. The myocardial wall is often thickened with a thin, compacted epicardial layer and a thickened endocardial layer." (Elliott et al., 2008)
has_exact_synonym: noncompaction cardiomyopathy

genetic hypertrophic cardiomyopathy
type: Class
equivalent class: Class
  intersection of: hypertrophic cardiomyopathy
  intersection of: Restriction
    on property: has material basis at all times
    some values from: genetic disorder
CVDO definition: A hypertrophic cardiomyopathy that has a genetic origin.

pericardium disease
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Class
    union of: Restriction
      on property: realized in
      some values from: Class
        intersection of: disease course
        intersection of: Restriction
    union of: Restriction
      on property: has material basis at all times
      some values from: pericardium disorder
CVDO definition: A disease affecting the pericardium.
CVDO editor note: Since pericardium is not a part of heart according to FMA, pericardium disease is not classified as a heart disease.

vascular disease - unclassified by CVDO
type: Class
subclass of: vascular disease
CVDO editor note: This is a dummy class not intended to be included in CVDO's final version, used to store temporarily DOID's vascular diseases that may be reclassified in the future.

cardiac atrium pathological process
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Cardiac atrium
CVDO definition: A pathological process occuring in a cardiac atrium.

cardiac ventricle pathological process
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Cardiac ventricle
CVDO definition: A pathological process occurring in a cardiac ventricle.

thromboembolism
type: Class
subclass of: pathological bodily process
subclass of: Restriction
  on property: occurs in
  some values from: Vascular tree
subclass of: Restriction
  on property: has occurrent part
  some values from: thrombosis
subclass of: Restriction
  on property: has occurrent part
  some values from: embolism
CVDO definition: A pathological process constituted by a thrombosis (creating a blood clot) and a subsequent embolism (involving the blood clot as the embolus).

infarction
type: Class
subclass of: pathological bodily process
CVDO definition: A necrosis of a tissue caused by a local lack of oxygen, due to an obstruction of the tissue's blood supply.

pulmonary valve leaflet displacement into the right ventricle during right ventricular diastole
type: Class
equivalent class: Class
  intersection of: heart valve leaflet displacement into a cardiac chamber
  intersection of: Restriction
    on property: part of occurrent
    some values from: right ventricular diastole
  intersection of: Restriction
    on property: has participant at all times
    some values from: Pulmonary valve

cardiac blood circulation pathological process
type: Class
subclass of: pathological bodily process
subclass of: Restriction
  on property: occurs in
  some values from: Heart
CVDO definition: A pathological process involving the blood circuation in the heart.

vascular blood circulation pathological process
type: Class
subclass of: pathological bodily process
subclass of: Restriction
  on property: occurs in
  some values from: Vascular tree
CVDO definition: A pathological process involving the blood circulation in a blood vessel.

part of atrial myocardium with impaired conduction
type: Class
subclass of: disorder
subclass of: Restriction
  on property: located in at all times
  some values from: Myocardium

diabetic microangiopathy
type: Class
subclass of: diabetic angiopathy

diabetic macroangiopathy
type: Class
subclass of: diabetic angiopathy

atheromous plaque formation in coronary artery
type: Class
equivalent class: Class
  intersection of: atheromous plaque formation in artery
  intersection of: Restriction
    on property: occurs in
    some values from: Coronary artery
CVDO definition: A pathological process consisting in the formation of atheromous plaques in a coronary artery. It may lead to a coronary stenosis.

atherosclerotic coronary heart disease
type: Class
equivalent class: Class
  intersection of: coronary heart disease
  intersection of: Restriction
    on property: has material basis at all times
    some values from: coronary stenosis
CVDO definition: A coronary heart disease due to a coronary stenosis.

left ventricular myocardium dilatation
type: Class
equivalent class: Class
  intersection of: ventricular myocardium dilatation
  intersection of: Restriction
    on property: occurs in
    some values from: Myocardium of left ventricle
CVDO definition: A pathological process of dilatation of the myocardium of a left cardiac ventricle.

supraventricular tachycardia (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: supraventricular tachycardia (process)

left atrial flutter (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: left atrial flutter (process)
disjoint with: right atrial flutter (disease)

right atrial flutter (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: right atrial flutter (process)

junctional tachycardia (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: junctional tachycardia (process)

atrioventricular nodal reentrant tachycardia (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: atrioventricular nodal reentrant tachycardia (process)

atrial flutter (process)
type: Class
subclass of: supraventricular tachycardia (process)

ventricular fibrillation (process)
type: Class
subclass of: ventricular tachyarrhythmia (process)

junctional tachycardia (process)
type: Class
subclass of: supraventricular tachycardia (process)

premature atrial contraction (process)
type: Class
subclass of: premature contraction (process)

cardiac arrhythmia (process)
type: Class
subclass of: heart conduction pathological process
CVDO definition: A pathological process involving the electrical activity of the heart.

heart block (process)
type: Class
subclass of: cardiac arrhythmia (process)

atrioventricular block (process)
type: Class
subclass of: heart block (process)

infra-hisian block (process)
type: Class
subclass of: heart block (process)

sinoatrial block (process)
type: Class
subclass of: heart block (process)

Mobitz I second degree atrioventricular block (process)
type: Class
subclass of: atrioventricular block (process)

Mobitz II second degree atrioventricular block (process)
type: Class
subclass of: atrioventricular block (process)

first degree atrioventricular block (process)
type: Class
subclass of: atrioventricular block (process)

third degree atrioventricular block (process)
type: Class
subclass of: atrioventricular block (process)

left anterior fascicular block (process)
type: Class
subclass of: infra-hisian block (process)

left bundle branch block (process)
type: Class
subclass of: infra-hisian block (process)

left posterior fascicular block (process)
type: Class
subclass of: infra-hisian block (process)

right bundle branch block (process)
type: Class
subclass of: infra-hisian block (process)

Mobitz I second degree sinoatrial block (process)
type: Class
subclass of: sinoatrial block (process)

Mobitz II second degree sinoatrial block (process)
type: Class
subclass of: sinoatrial block (process)

first degree sinoatrial block (process)
type: Class
subclass of: sinoatrial block (process)

third degree sinoatrial block (process)
type: Class
subclass of: sinoatrial block (process)

coronary artery disorder
type: Class
equivalent class: Class
  intersection of: disorder
  intersection of: Restriction
    on property: located in at all times
    some values from: Coronary artery
CVDO definition: A disorder always located in a coronary artery.

ventricular myocardium dilatation
type: Class
subclass of: pathological bodily process
subclass of: Restriction
  on property: occurs in
  some values from: Myocardium of ventricle
CVDO definition: A pathological process of dilatation of the myocardium of a cardiac ventricle.

ventricular myocardium hypertrophy
type: Class
subclass of: pathological bodily process
subclass of: Restriction
  on property: occurs in
  some values from: Myocardium of ventricle
CVDO definition: A pathological process of hypertrophy of the myocardium of a cardiac ventricle.

left ventricular myocardium hypertrophy
type: Class
equivalent class: Class
  intersection of: ventricular myocardium hypertrophy
  intersection of: Restriction
    on property: occurs in
    some values from: Myocardium of left ventricle
CVDO definition: A pathological process of hypertrophy of the myocardium of a left cardiac ventricle.

right ventricular myocardium hypertrophy
type: Class
equivalent class: Class
  intersection of: ventricular myocardium hypertrophy
  intersection of: Restriction
    on property: occurs in
    some values from: Myocardium of right ventricle
CVDO definition: A pathological process of hypertrophy of the myocardium of a right cardiac ventricle.

pathological inflammation process
type: Class
subclass of: pathological bodily process
CVDO definition: A pathological process of an organ or part of organ getting inflamed.

inflammation process in a myocardium
type: Class
equivalent class: Class
  intersection of: pathological inflammation process
  intersection of: Restriction
    on property: occurs in
    some values from: Myocardium
CVDO definition: An inflammation process occurring in the myocardium.

inflammation process in an endocardium
type: Class
equivalent class: Class
  intersection of: pathological inflammation process
  intersection of: Restriction
    on property: occurs in
    some values from: Endocardium
CVDO definition: An inflammation process occurring in the endocardium.

inflammation process in a pericardium
type: Class
equivalent class: Class
  intersection of: pathological inflammation process
  intersection of: Restriction
    on property: occurs in
    some values from: Pericardium
CVDO definition: An inflammation process occurring in the pericardium.

inflammation process in aorta
type: Class
equivalent class: Class
  intersection of: pathological inflammation process
  intersection of: Restriction
    on property: occurs in
    some values from: Aorta
CVDO definition: An inflammation process occurring in the aorta.

inflammation process in a blood vessel
type: Class
equivalent class: Class
  intersection of: pathological inflammation process
  intersection of: Restriction
    on property: occurs in
    some values from: Vascular tree
CVDO definition: An inflammation process in a blood vessel.

inflammation process in a femoral vein
type: Class
equivalent class: Class
  intersection of: pathological inflammation process
  intersection of: Restriction
    on property: occurs in
    some values from: Femoral vein
CVDO definition: An inflammation process occurring in the femoral vein.

inflammation process in an iliac vein
type: Class
equivalent class: Class
  intersection of: pathological inflammation process
  intersection of: Class
    union of: Restriction
      on property: occurs in
      some values from: Common iliac vein
    union of: Restriction
      on property: occurs in
      some values from: External iliac vein
    union of: Restriction
      on property: occurs in
      some values from: Internal iliac vein
CVDO definition: An inflammation process occurring in an iliac vein.

inflammation process in a retinal artery
type: Class
equivalent class: Class
  intersection of: pathological inflammation process
  intersection of: Restriction
    on property: occurs in
    some values from: Central retinal artery
CVDO definition: An inflammation of the retinal artery.

inflammation process in a vein
type: Class
equivalent class: Class
  intersection of: pathological inflammation process
  intersection of: Restriction
    on property: occurs in
    some values from: Vein
CVDO definition: An inflammation process occurring in a vein.

fibrofatty replacement in a right ventricular myocardium
type: Class
subclass of: pathological bodily process
subclass of: Restriction
  on property: occurs in
  some values from: Right ventricle
subclass of: Restriction
  on property: has participant at all times
  some values from: Myocardium of right ventricle
comment: A pathological process of fibrofatty replacement in the myocardium of the right cardiac ventricle.

degenerated structure in a heart valve leaflet
type: Class
subclass of: disorder
subclass of: Restriction
  on property: located in at all times
  some values from: Cardiac valve
definition: A disorder of degenerated structure in a heart valve leaflet.

degenerated structure in an aortic valve leaflet
type: Class
equivalent class: Class
  intersection of: degenerated structure in a heart valve leaflet
  intersection of: Restriction
    on property: located in at all times
    some values from: Aortic valve
CVDO definition: A disorder of degenerated structure in an aortic valve leaflet.

degenerated structure in a mitral valve leaflet
type: Class
equivalent class: Class
  intersection of: degenerated structure in a heart valve leaflet
  intersection of: Restriction
    on property: located in at all times
    some values from: Mitral valve
CVDO definition: A disorder of degenerated structure in a mitral valve leaflet.

degenerated structure in a tricuspid valve leaflet
type: Class
equivalent class: Class
  intersection of: degenerated structure in a heart valve leaflet
  intersection of: Restriction
    on property: located in at all times
    some values from: Tricuspid valve
CVDO definition: A (clinically abnormal) degenerated structure in a tricuspid valve leaflet.

degenerated structure in a pulmonary valve leaflet
type: Class
equivalent class: Class
  intersection of: degenerated structure in a heart valve leaflet
  intersection of: Restriction
    on property: located in at all times
    some values from: Pulmonary valve
CVDO definition: A disorder of degenerated structure in a pulmonary valve leaflet.

Barlow's syndrome
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: mitral valve leaflet displacement into the left atrium during left ventricular systole
  intersection of: Restriction
    on property: has material basis at all times
    some values from: myxomatous degenerated structure in a mitral valve leaflet
CVDO definition: A mitral valve prolapse due to myxomatous proliferation in the mitral valve.

fluid accumulation in the pericardial cavity
type: Class
subclass of: pathological bodily process
subclass of: Restriction
  on property: occurs in
  some values from: Pericardium
CVDO definition: A pathological process consisting in the abnormal accumulation of fluid in the pericardial cavity.
CVDO editor note: A process of pericardial effusion leads to the disorder 'fluid in the pericardial cavity'.

atherosclerotic ischemic cardiomyopathy
type: Class
subclass of: ischemic cardiomyopathy
subclass of: Restriction
  on property: has material basis at all times
  some values from: coronary stenosis
CVDO definition: An ischemic cardiomyopathy due to coronary stenosis.

paroxysmal atrial fibrillation
type: Class
subclass of: atrial fibrillation (disease)
CVDO definition: An atrial fibrillation disease that is characterized by an atrial fibrillation episode shorter than 7 days.

persistent atrial fibrillation
type: Class
subclass of: atrial fibrillation (disease)
CVDO definition: An atrial fibrillation disease that is characterized by an atrial fibrillation episode longer than 7 days which does terminate by cardioversion.

premature contraction (process)
type: Class
subclass of: cardiac arrhythmia (process)

premature junctional contraction (process)
type: Class
subclass of: premature contraction (process)

premature ventricular contraction (process)
type: Class
subclass of: premature contraction (process)

sinoatrial arrest (process)
type: Class
subclass of: cardiac arrhythmia (process)
has_exact_synonym: sinus pause

sinus bradycardia (process)
type: Class
subclass of: bradycardia (process)

tachycardia (process)
type: Class
subclass of: cardiac arrhythmia (process)
has_exact_synonym: tachyarrhythmia (process)

left atrial flutter (process)
type: Class
subclass of: atrial flutter (process)

right atrial flutter (process)
type: Class
subclass of: atrial flutter (process)

common atrial flutter (process)
type: Class
subclass of: right atrial flutter (process)

atrioventricular nodal reentrant tachycardia (process)
type: Class
subclass of: junctional tachycardia (process)

ventricular tachycardia (process)
type: Class
subclass of: ventricular tachyarrhythmia (process)

monomorphic ventricular tachycardia (process)
type: Class
subclass of: ventricular tachycardia (process)

torsades de pointes (process)
type: Class
subclass of: ventricular tachycardia (process)

ventricular flutter (process)
type: Class
subclass of: ventricular tachycardia (process)

inappropriate sinus tachycardia (process)
type: Class
subclass of: tachycardia (process)

ventricular preexcitation (process)
type: Class
subclass of: anomalous atrioventricular excitation (process)

coronary artery hardening
type: Class
equivalent class: Class
  intersection of: artery hardening
  intersection of: Restriction
    on property: occurs in
    some values from: Coronary artery
CVDO definition: A pathological process of a coronary artery hardening.

accessory bundle
type: Class
subclass of: heart disorder

atrioventricular accessory bundle
type: Class
subclass of: accessory bundle
CVDO definition: Accessory bundle that connects the atrium to a ventricle outside of the regular atrioventricular conduction system.

impaired sinus node
type: Class
subclass of: heart conduction disorder

tachycardia-bradycardia syndrome
type: Class
subclass of: sick sinus syndrome
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: atrial fibrillation (process)
definition: A sick sinus syndrome characterized by sinus pauses and/or bradycardia episodes alternating with sinus or atrial tachycardia episodes.

inappropriate sinus tachycardia (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: inappropriate sinus tachycardia (process)

cardiac channelopathy
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: has material basis at all times
    some values from: cardiac ion channels disorder
CVDO definition: A disease cause by a cardiac ion channel disorder.

long QT syndrome
type: Class
subclass of: cardiac channelopathy
CVDO definition: A cardiac channelopathy in which delayed repolarization of the heart following a heartbeat increases the risk of episodes of torsades de pointes. This is a rare disease.

genetic cardiac channelopathy
type: Class
equivalent class: Class
  intersection of: cardiac channelopathy
  intersection of: Restriction
    on property: has material basis at all times
    some values from: genetic disorder
CVDO definition: A cardiac channelopathy that has a genetic origin.

sinus bradycardia (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: sinus bradycardia (process)

left bundle branch block (process)
type: Class
subclass of: left anterior fascicular block (process)

tachycardia (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: tachycardia (process)
has_exact_synonym: tachyarrhythmia (disease)

sinoatrial arrest (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: sinoatrial arrest (process)

atrioventricular reciprocating tachycardia (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: atrioventricular reciprocating tachycardia (process)

ventricular tachycardia (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: ventricular tachycardia (process)

ventricular flutter (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: ventricular flutter (process)

torsades de pointes (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: torsades de pointes (process)

monomorphic ventricular tachycardia (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: monomorphic ventricular tachycardia (process)

ventricular fibrillation (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: ventricular fibrillation (process)

ventricular tachyarrhythmia (process)
type: Class
subclass of: tachycardia (process)

atrioventricular reciprocating tachycardia (process)
type: Class
subclass of: junctional tachycardia (process)

premature contraction (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: premature contraction (process)

premature junctional contraction (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: premature junctional contraction (process)

premature ventricular contraction (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: premature ventricular contraction (process)

cardiac chamber pathological process
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Cardiac chamber
CVDO definition: A pathological process occurring in a cardiac chamber.

mitral valve disorder
type: Class
equivalent class: Class
  intersection of: disorder
  intersection of: Restriction
    on property: located in at all times
    some values from: Mitral valve
CVDO definition: A disorder always located in the mitral valve.

aortic valve disorder
type: Class
equivalent class: Class
  intersection of: disorder
  intersection of: Restriction
    on property: located in at all times
    some values from: Aortic valve
CVDO definition: A disorder always located in the aortic valve.

tricuspid valve disorder
type: Class
equivalent class: Class
  intersection of: disorder
  intersection of: Restriction
    on property: located in at all times
    some values from: Tricuspid valve
CVDO definition: A disorder always located in the tricuspid valve.

pulmonary valve disorder
type: Class
equivalent class: Class
  intersection of: disorder
  intersection of: Restriction
    on property: located in at all times
    some values from: Pulmonary valve
CVDO definition: A disorder always located in the pulmonary valve.

heart valve improper opening
type: Class
subclass of: pathological bodily process
subclass of: Restriction
  on property: occurs in
  some values from: Heart
subclass of: Restriction
  on property: has participant at all times
  some values from: Cardiac valve
definition: A pathological process of a heart valve improper opening.

aortic valve improper opening during left ventricular systole
type: Class
equivalent class: Class
  intersection of: heart valve improper opening
  intersection of: Restriction
    on property: part of occurrent
    some values from: left ventricular systole
  intersection of: Restriction
    on property: has participant at all times
    some values from: Aortic valve

mitral valve narrowed opening during left ventricular diastole
type: Class
equivalent class: Class
  intersection of: heart valve improper opening
  intersection of: Restriction
    on property: part of occurrent
    some values from: left ventricular diastole
  intersection of: Restriction
    on property: has participant at all times
    some values from: Mitral valve

pulmonary valve narrowed opening during right ventricular systole
type: Class
equivalent class: Class
  intersection of: heart valve improper opening
  intersection of: Restriction
    on property: part of occurrent
    some values from: right ventricular systole
  intersection of: Restriction
    on property: has participant at all times
    some values from: Pulmonary valve

tricuspid valve narrowed opening during right ventricular diastole
type: Class
equivalent class: Class
  intersection of: heart valve improper opening
  intersection of: Restriction
    on property: part of occurrent
    some values from: right ventricular diastole
  intersection of: Restriction
    on property: has participant at all times
    some values from: Tricuspid valve

coronary heart disease with stable angina
type: Class
equivalent class: Class
  intersection of: coronary heart disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: stable angina pectoris
definition: A coronary heart disease leading to stable angina.

atherosclerotic acute coronary syndrome
type: Class
equivalent class: Class
  intersection of: acute coronary syndrome
  intersection of: Restriction
    on property: has material basis at all times
    some values from: coronary stenosis
CVDO definition: An acute coronary syndrome due to coronary stenosis.

angina pectoris
type: Class
subclass of: heart ischemia
disjoint union of: stable angina pectoris
disjoint union of: unstable angina pectoris
CVDO definition: A heart ischemia accompanied by pain.
CVDO editor note: Angina pectoris is sometimes taken to refer to the pain itself, rather than to the pathological process behind it.

stable angina pectoris
type: Class
subclass of: angina pectoris
CVDO definition: An angina that is not unstable.

unstable angina pectoris
type: Class
subclass of: angina pectoris
subclass of: Restriction
  on property: part of occurrent
  some values from: Class
    intersection of: acute disease course
    intersection of: Restriction
      on property: realizes
      some values from: acute coronary syndrome
CVDO definition: An angina that worsens. It has at least one of these three features: 1. it occurs at rest (or with minimal exertion), usually lasting >10 min 2. it is severe and of new onset (i.e., within the prior 4–6 weeks) 3. it occurs with a crescendo pattern (i.e., distinctly more severe, prolonged, or frequent than before).

heart pathological process involving a mitral valve
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Heart
  intersection of: Restriction
    on property: has participant at all times
    some values from: Mitral valve
definition: A heart pathological process that has a mitral valve as a participant.

heart pathological process involving an aortic valve
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Heart
  intersection of: Restriction
    on property: has participant at all times
    some values from: Aortic valve
CVDO definition: A heart pathological process that has an aortic valve as a participant.

heart pathological process involving a tricuspid valve
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Heart
  intersection of: Restriction
    on property: has participant at all times
    some values from: Tricuspid valve
definition: A heart pathological process that has a tricuspid valve as a participant.

heart pathological process involving a pulmonary valve
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Heart
  intersection of: Restriction
    on property: has participant at all times
    some values from: Pulmonary valve
definition: A heart pathological process that has a pulmonary valve as a participant.

heart valve leaflet displacement into a cardiac chamber during ventricular diastole
type: Class
equivalent class: Class
  intersection of: heart valve leaflet displacement into a cardiac chamber
  intersection of: Restriction
    on property: part of occurrent
    some values from: ventricular diastole

ventricular systole
type: Class
subclass of: heart bodily process
subclass of: Restriction
  on property: has participant at all times
  some values from: Cardiac ventricle

ventricular diastole
type: Class
subclass of: heart bodily process
subclass of: Restriction
  on property: has participant at all times
  some values from: Cardiac ventricle

atrial systole
type: Class
subclass of: heart bodily process

atrial diastole
type: Class
subclass of: heart bodily process

left ventricular diastole
type: Class
subclass of: ventricular diastole
subclass of: Restriction
  on property: has participant at all times
  some values from: Left ventricle

right ventricular diastole
type: Class
subclass of: ventricular diastole
subclass of: Restriction
  on property: has participant at all times
  some values from: Right ventricle

left ventricular systole
type: Class
subclass of: ventricular systole
subclass of: Restriction
  on property: has participant at all times
  some values from: Left ventricle

right ventricular systole
type: Class
subclass of: ventricular systole
subclass of: Restriction
  on property: has participant at all times
  some values from: Right ventricle

left atrial systole
type: Class
subclass of: atrial systole

right atrial systole
type: Class
subclass of: atrial systole

left atrial diastole
type: Class
subclass of: atrial diastole

right atrial diastole
type: Class
subclass of: atrial diastole

heart valve leaflet displacement into a cardiac chamber
type: Class
subclass of: heart valve improper close
subclass of: Restriction
  on property: occurs in
  some values from: Heart
subclass of: Restriction
  on property: has participant at all times
  some values from: Cardiac valve
definition: A pathological process of a heart valve being displaced into a cardiac chamber.

fluid in the pericardial cavity
type: Class
subclass of: disorder
subclass of: Restriction
  on property: located in at all times
  some values from: Pericardium
CVDO definition: A disorder of fluid in the pericardial cavity.

blood in the pericardial cavity
type: Class
subclass of: fluid in the pericardial cavity
CVDO definition: A disorder of blood in the pericardial cavity.

heart conduction pathological process
type: Class
subclass of: pathological bodily process
subclass of: Restriction
  on property: occurs in
  some values from: Conducting tissue of heart

anomalous atrioventricular excitation (process)
type: Class
subclass of: cardiac arrhythmia (process)

ventricular preexcitation (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: ventricular preexcitation (process)

cardiac ion channels disorder
type: Class
subclass of: heart conduction disorder
CVDO definition: A disorder in the heart conduction system that causes a disturbed function of ion channel subunits or the proteins that regulate them.

pulmonary valve prolapse
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: pulmonary valve leaflet displacement into the right ventricle during right ventricular diastole
  intersection of: Restriction
    on property: has material basis at all times
    some values from: degenerated structure in a pulmonary valve leaflet
CVDO definition: A disease characterized by the displacement of a degenerated pulmonary valve leaflet into the right ventricle during diastole.

impaired anterior division of left branch of atrioventricular bundle
type: Class
subclass of: heart conduction disorder

ventricular tachyarrhythmia (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: ventricular tachyarrhythmia (process)

inflammation process in a heart valve
type: Class
equivalent class: Class
  intersection of: pathological inflammation process
  intersection of: Restriction
    on property: occurs in
    some values from: Cardiac valve
CVDO definition: An inflammation process occurring in a heart valve.

heart bodily process
type: Class
subclass of: bodily process

genetic dilated cardiomyopathy
type: Class
equivalent class: Class
  intersection of: dilated cardiomyopathy
  intersection of: Restriction
    on property: has material basis at all times
    some values from: genetic disorder
CVDO definition: A dilated cardiomyopathy that has a genetic origin.

genetic cardiomyopathy
type: Class
equivalent class: Class
  intersection of: cardiomyopathy (2008 definition)
  intersection of: Restriction
    on property: has material basis at all times
    some values from: genetic disorder
CVDO definition: A cardiomyopathy (2008) that has a genetic origin.

embolus
type: Class
subclass of: disorder
subclass of: Restriction
  on property: located in at all times
  some values from: Vascular tree
comment: A disorder made of a detached, traveling intravascular matter (solid, liquid, or gaseous) carried by circulation. It is capable of creating an arterial occlusion at a site distant from its point of origin.

inflammatory disease
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: pathological inflammation process
CVDO definition: A disease characterized by an inflammation process.

myocardium pathological process
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Myocardium
comment: A pathological process occurring in the myocardium.

aorta pathological process
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Aorta
subclass of: pathological bodily process
CVDO definition: A pathological process involving or occuring in the aorta.

aorta disorder
type: Class
equivalent class: Class
  intersection of: disorder
  intersection of: Restriction
    on property: located in at all times
    some values from: Aorta
CVDO definition: A disorder always located in the aorta.

endocardium pathological process
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Endocardium
subclass of: pathological bodily process
CVDO definition: A pathological process occuring in the endocardium.

endocardium thickening
type: Class
subclass of: pathological bodily process
subclass of: Restriction
  on property: occurs in
  some values from: Endocardium
CVDO definition: A pathological process of thickening of the endocardium.

endocardium disease
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Class
    union of: Restriction
      on property: realized in
      some values from: Class
        intersection of: disease course
        intersection of: Restriction
    union of: Restriction
      on property: has material basis at all times
      some values from: endocardium disorder
comment: A disease affecting the endocardium.

left ventricle disorder
type: Class
equivalent class: Class
  intersection of: disorder
  intersection of: Restriction
    on property: located in at all times
    some values from: Left ventricle
CVDO definition: A disorder always located in the left heart ventricle.

right ventricle disorder
type: Class
equivalent class: Class
  intersection of: disorder
  intersection of: Restriction
    on property: located in at all times
    some values from: Right ventricle
CVDO definition: A disorder always located in the right heart ventricle.

heart ventricle disorder
type: Class
equivalent class: Class
  intersection of: disorder
  intersection of: Restriction
    on property: located in at all times
    some values from: Cardiac ventricle
CVDO definition: A disorder always located in a heart ventricle.

heart ischemia
type: Class
subclass of: ischemia
CVDO definition: An ischemia of the heart.

vein pathological process
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Vein

ischemic cardiomyopathy
type: Class
subclass of: ischemic heart disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: left ventricular myocardium dilatation
    intersection of: Restriction
      on property: has occurrent part
      some values from: left ventricular myocardium contraction dysfunctional process
CVDO definition: An ischemic heart disease leading to a dilatation and dysfunction of the left ventricle.

material anatomical entity disorder
type: Class
equivalent class: Class
  intersection of: disorder
  intersection of: Restriction
    on property: located in at all times
    some values from: Material anatomical entity
comment: A disorder located in an anatomical entity.

material anatomical entity pathological process
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Material anatomical entity

cardiovascular system disorder
type: Class
equivalent class: Class
  intersection of: disorder
  intersection of: Restriction
    on property: located in at all times
    some values from: Cardiovascular system
subclass of: disorder

cardiovascular system pathological process
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Cardiovascular system
subclass of: pathological bodily process

disease of material anatomical entity
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Class
    union of: Restriction
      on property: realized in
      some values from: Class
        intersection of: disease course
        intersection of: Restriction
    union of: Restriction
      on property: has material basis at all times
      some values from: material anatomical entity disorder
subclass of: disease
comment: A disease that affects a material anatomical entity.

valvular cardiomyopathy
type: Class
subclass of: disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: progressive disease course
    intersection of: Class
      union of: Restriction
        on property: has occurrent part
        some values from: left ventricular myocardium dilatation
      union of: Restriction
        on property: has occurrent part
        some values from: left ventricular myocardium hypertrophy
    intersection of: Restriction
      on property: has occurrent part
      some values from: aortic valve improper opening during left ventricular systole
    intersection of: Restriction
      on property: has occurrent part
      some values from: left ventricular myocardium contraction dysfunctional process
subclass of: Restriction
  on property: has material basis at all times
  some values from: aortic valve disorder
CVDO definition: An aortic valve stenosis leading to a hypertrophy or dilatation of the left ventricle and its dysfunction.

cardiomyopathy (2008 definition)
type: Class
subclass of: disease
CVDO definition: A heart disease in which the heart muscle is structurally and functionally abnormal, in the absence of coronary artery disease, hypertension, valvular disease and congenital heart disease sufficient to cause the observed myocardial abnormality. (adapted from Elliott et al., 2008, European Heart Journal, 29, 270-276)
CVDO editor note: Contemporary (e.g. Elliott et al. 2008) definitions of cardiomyopathy exclude ischemic cardiomyopathy, hypertensive cardiomyopathy and valvular cardiomyopathy.

left ventricular myocardium contraction dysfunctional process
type: Class
equivalent class: Class
  intersection of: myocardium contraction dysfunctional process
  intersection of: Restriction
    on property: occurs in
    some values from: Myocardium of left ventricle

myocardium contraction dysfunctional process
type: Class
subclass of: pathological bodily process
subclass of: Restriction
  on property: occurs in
  some values from: Myocardium

left ventricle pathological process
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Left ventricle
CVDO editor note: A pathological process occurring in the left heart ventricle.

right ventricle pathological process
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Right ventricle
CVDO definition: A pathological process occurring in the right heart ventricle.

inflammatory dilated cardiomyopathy
type: Class
subclass of: dilated cardiomyopathy
CVDO definition: "Inflammatory DCM is defined by the presence of chronic inflammatory cells in association with left ventricular dilatation and reduced ejection fraction". (Elliott et al., 2008)
has_exact_synonym: inflammatory dilated cardiomyopathy

hypertensive cardiomyopathy
type: Class
subclass of: hypertensive heart disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: left ventricular myocardium hypertrophy
    intersection of: Restriction
      on property: has occurrent part
      some values from: left ventricular myocardium contraction dysfunctional process
CVDO definition: A hypertensive heart disease leading to a hypertrophy and dysfunction of the left ventricle.

congenital heart disease
type: Class
subclass of: heart disease
CVDO definition: A heart disease existing at birth, or developping during the first month after birth.

heart ventricle disease
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Class
    union of: Restriction
      on property: realized in
      some values from: Class
        intersection of: disease course
        intersection of: Restriction
    union of: Restriction
      on property: has material basis at all times
      some values from: heart ventricle disorder
subclass of: disease
CVDO definition: A disease affecting a heart ventricle.

left ventricle disease
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Class
    union of: Restriction
      on property: realized in
      some values from: Class
        intersection of: disease course
        intersection of: Restriction
    union of: Restriction
      on property: has material basis at all times
      some values from: left ventricle disorder
subclass of: disease
CVDO definition: A disease affecting a heart left ventricle.

right ventricle disease
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Class
    union of: Restriction
      on property: realized in
      some values from: Class
        intersection of: disease course
        intersection of: Restriction
    union of: Restriction
      on property: has material basis at all times
      some values from: right ventricle disorder
subclass of: disease
CVDO definition: A disease affecting a heart right ventricle.

ventricular myocardium contraction dysfunctional process
type: Class
equivalent class: Class
  intersection of: myocardium contraction dysfunctional process
  intersection of: Restriction
    on property: occurs in
    some values from: Myocardium of ventricle

right ventricular myocardium contraction dysfunctional process
type: Class
equivalent class: Class
  intersection of: myocardium contraction dysfunctional process
  intersection of: Restriction
    on property: occurs in
    some values from: Myocardium of right ventricle
subclass of: myocardium contraction dysfunctional process

myocardium of left ventricle stiffening
type: Class
subclass of: pathological bodily process
subclass of: Restriction
  on property: occurs in
  some values from: Myocardium of left ventricle

heart valve pathological process
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Cardiac valve
CVDO definition: A pathological process occurring in a heart valve.

aortic valve pathological process
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Aortic valve
subclass of: pathological bodily process
CVDO definition: A pathological process occurring in an aortic valve.

mitral valve pathological process
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Mitral valve
CVDO definition: A pathological process occurring in a mitral valve.

tricuspid valve pathological process
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Tricuspid valve
CVDO definition: A pathological process occurring in a tricuspid valve.

pulmonary valve pathological process
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Pulmonary valve
CVDO definition: A pathological process occurring in a pulmonary valve.

myocardium disease
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Class
    union of: Restriction
      on property: realized in
      some values from: Class
        intersection of: disease course
        intersection of: Restriction
    union of: Restriction
      on property: has material basis at all times
      some values from: myocardium disorder
subclass of: disease
CVDO definition: A disease affecting the myocardium.

genetic heart disease
type: Class
equivalent class: Class
  intersection of: heart disease
  intersection of: Restriction
    on property: has material basis at all times
    some values from: genetic disorder
CVDO definition: A heart disease that has a genetic disorder.

congenital disease
type: Class
subclass of: disease
CVDO definition: A disease existing at birth, or developping during the first month after birth.

coronary artery pathological process
type: Class
equivalent class: Class
  intersection of: pathological bodily process
  intersection of: Restriction
    on property: occurs in
    some values from: Coronary artery

coronary artery smooth muscle constriction
type: Class
subclass of: pathological bodily process
subclass of: Restriction
  on property: occurs in
  some values from: Coronary artery
CVDO editor note: A pathological process of coronary artery smooth muscle constriction.

vascular tissue disease
type: Class
subclass of: vascular disease - unclassified by CVDO
imported from: doid.owl
has_obo_namespace: disease_ontology
id: DOID:0000405

arrhythmogenic right ventricular dysplasia
type: Class
subclass of: disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: progressive disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: fibrofatty replacement in a right ventricular myocardium
    intersection of: Restriction
      on property: has occurrent part
      some values from: right ventricular myocardium contraction dysfunctional process
subclass of: Restriction
  on property: has material basis at all times
  some values from: genetic disorder
CVDO definition: A cardiomyopathy characterized by adipose and fibrosis infiltration in the right ventricular myocardium. It is caused by genetic defects of desmosomes (which are parts of the myocardium) and may result in arrhythmia.
imported from: doid.owl
database_cross_reference: MSH:D019571
database_cross_reference: OMIM:107970
database_cross_reference: OMIM:600996
database_cross_reference: OMIM:604400
database_cross_reference: OMIM:607450
database_cross_reference: OMIM:609040
database_cross_reference: OMIM:610193
database_cross_reference: OMIM:610476
database_cross_reference: OMIM:611528
has_exact_synonym: ARRHYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY 1
has_exact_synonym: ARVD
has_exact_synonym: arrhythmogenic right ventricular dysplasia/cardiomyopathy
has_obo_namespace: disease_ontology
id: DOID:0050431
comment: OMIM mapping confirmed by DO. [SN].

Brugada syndrome
type: Class
subclass of: cardiac channelopathy
subclass of: Restriction
  on property: has material basis at all times
  some values from: genetic disorder
subclass of: Restriction
  on property: realized in
  all values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: ventricular tachyarrhythmia (process)
CVDO definition: A heart conduction disease that is characterised by abnormal electrocardiogram (ECG) findings and an increased risk of sudden cardiac death by ventricular tachyarrhytmia.
definition: A heart conduction disease that is characterised by abnormal electrocardiogram (ECG) findings and an increased risk of sudden cardiac death.
imported from: doid.owl
database_cross_reference: MSH:D053840
database_cross_reference: OMIM:601144
database_cross_reference: OMIM:611777
database_cross_reference: OMIM:611875
database_cross_reference: OMIM:611876
database_cross_reference: OMIM:612838
database_cross_reference: OMIM:613119
database_cross_reference: OMIM:613120
database_cross_reference: OMIM:613123
has_obo_namespace: disease_ontology
id: DOID:0050451
comment: OMIM mapping confirmed by DO. [SN].

generalized arterial calcification of infancy
type: Class
subclass of: vascular disease - unclassified by CVDO
imported from: doid.owl
database_cross_reference: OMIM:208000
has_exact_synonym: IDIOPATHIC INFANTILE ARTERIAL CALCIFICATION
has_obo_namespace: disease_ontology
id: DOID:0050644
comment: OMIM mapping confirmed by DO. [SN].

arterial tortuosity syndrome
type: Class
subclass of: vascular disease - unclassified by CVDO
imported from: doid.owl
database_cross_reference: OMIM:208050
has_obo_namespace: disease_ontology
id: DOID:0050645
comment: OMIM mapping confirmed by DO. [SN].

familial atrial fibrillation
type: Class
subclass of: atrial fibrillation (disease)
subclass of: Restriction
  on property: has material basis at all times
  some values from: genetic disorder
CVDO definition: An atrial fibrillation disease that has a genetic origin.
definition: A heart conduction disease that is characterized by uncoordinated electrical activity in the heart's upper chambers (the atria), which causes the heartbeat to become fast and irregular and has_material_basis_in autosomal dominant inheritance of the familial atrial fibrillation (ATFB) genes.
imported from: doid.owl
database_cross_reference: OMIM:607554
database_cross_reference: OMIM:611493
database_cross_reference: OMIM:612201
database_cross_reference: OMIM:612240
has_obo_namespace: disease_ontology
id: DOID:0050650

cardiomyopathy (1995 definition)
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: ventricular myocardium contraction dysfunctional process
disjoint union of: cardiomyopathy (2008 definition)
disjoint union of: Class
  intersection of: congenital heart disease
  intersection of: cardiomyopathy (1995 definition)
disjoint union of: Class
  intersection of: cardiomyopathy (1995 definition)
  intersection of: hypertensive heart disease
disjoint union of: Class
  intersection of: cardiomyopathy (1995 definition)
  intersection of: coronary heart disease
disjoint union of: Class
  intersection of: cardiomyopathy (1995 definition)
  intersection of: heart valve disease
CVDO definition: Disease of the myocardium associated with cardiac dysfunction. (Report of the 1995 World Health Organization/International Society and Federation of Cardiology Task Force on the Definition and Classification of Cardiomyopathies)
CVDO editor note: DOID label "cardiomyopathy" was changed.
definition: A heart disease that is characterized by deterioration of the funciton of the heart muscle.
imported from: doid.owl
created by: lschriml
creation date: 2012-01-03T02:54:11Z
has_obo_namespace: disease_ontology
id: DOID:0050700

infective endocarditis
type: Class
subclass of: disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: inflammation process in an endocardium
CVDO definition: An endocarditis caused by infection.
definition: A heart disease involving inflammation of the endocardium (inner layer of the heart) caused by bacterial infection.
imported from: doid.owl
has_obo_namespace: disease_ontology
id: DOID:0060000

non-bacterial thrombotic endocarditis
type: Class
subclass of: disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: inflammation process in an endocardium
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: inflammation process in a heart valve
CVDO definition: An non-infective endocarditis that results in the deposition of small sterile vegetations on valve leaflets.
CVDO editor note: DOID label 'marantic endocarditis' was changed in CVDO (non-bacterial thrombotic endocarditis is a more common name).
imported from: doid.owl
created by: lschriml
creation date: 2011-04-13T03:14:26Z
has_exact_synonym: marantic endocarditis
has_obo_namespace: disease_ontology
id: DOID:0060068

cerebral artery occlusion
type: Class
subclass of: cerebrovascular disease
imported from: doid.owl
database_cross_reference: ICD9CM:434
database_cross_reference: ICD9CM:434.9
database_cross_reference: SNOMEDCT_2010_1_31:155400001
database_cross_reference: SNOMEDCT_2010_1_31:155403004
database_cross_reference: SNOMEDCT_2010_1_31:195188006
database_cross_reference: SNOMEDCT_2010_1_31:20059004
database_cross_reference: SNOMEDCT_2010_1_31:266255008
database_cross_reference: SNOMEDCT_2010_1_31:286956007
database_cross_reference: UMLS_CUI:C0028790
has_obo_namespace: disease_ontology
id: DOID:10127

venous insufficiency
type: Class
subclass of: disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: vein pathological process
imported from: doid.owl
database_cross_reference: ICD9CM:459.81
database_cross_reference: MSH:D014689
database_cross_reference: SNOMEDCT_2010_1_31:20696009
database_cross_reference: UMLS_CUI:C0042485
has_exact_synonym: peripheral venous insufficiency
has_obo_namespace: disease_ontology
id: DOID:10128

malignant hypertensive renal disease
type: Class
subclass of: renal hypertension
imported from: doid.owl
database_cross_reference: SNOMEDCT_2010_1_31:65443008
database_cross_reference: UMLS_CUI:C0155593
has_obo_namespace: disease_ontology
id: DOID:10177

aortic atherosclerosis
type: Class
subclass of: atherosclerosis
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: Class
        intersection of: atheromous plaque formation in artery
        intersection of: Restriction
imported from: doid.owl
database_cross_reference: ICD9CM:440.0
database_cross_reference: SNOMEDCT_2010_1_31:155415000
database_cross_reference: SNOMEDCT_2010_1_31:195252007
database_cross_reference: SNOMEDCT_2010_1_31:81817003
database_cross_reference: UMLS_CUI:C0155733
has_exact_synonym: Aortic atherosclerosis
has_exact_synonym: Atherosclerosis of aorta (disorder)
has_obo_namespace: disease_ontology
id: DOID:10230

histoplasmosis pericarditis
type: Class
subclass of: fungal pericarditis
imported from: doid.owl
database_cross_reference: ICD9CM:115.93
database_cross_reference: SNOMEDCT_2010_1_31:187059008
database_cross_reference: UMLS_CUI:C0153279
has_exact_synonym: Histoplasmosis with pericarditis (disorder)
has_obo_namespace: disease_ontology
id: DOID:10234

subendocardial infarction acute myocardial infarction
type: Class
subclass of: acute myocardial infarction
imported from: doid.owl
database_cross_reference: ICD9CM:410.7
database_cross_reference: UMLS_CUI:C0155655
has_obo_namespace: disease_ontology
id: DOID:10266

left anterior fascicular block (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: left anterior fascicular block (process)
subclass of: Restriction
  on property: has material basis at all times
  some values from: impaired anterior division of left branch of atrioventricular bundle
CVDO editor note: DOID label changed to 'left anterior fascicular block (disease)' for symmetry reasons with 'left posterior fascicular block (disease)'
imported from: doid.owl
database_cross_reference: ICD9CM:426.2
database_cross_reference: SNOMEDCT_2010_1_31:195044001
database_cross_reference: SNOMEDCT_2010_1_31:195045000
database_cross_reference: SNOMEDCT_2010_1_31:266245009
database_cross_reference: SNOMEDCT_2010_1_31:4973001
database_cross_reference: UMLS_CUI:C0155702
has_exact_synonym: Left bundle branch [block] or [hemiblock]
has_exact_synonym: Left bundle branch hemiblock (disorder)
has_exact_synonym: Left bundle branch hemiblock NOS (disorder)
has_exact_synonym: left bundle branch hemiblock
has_obo_namespace: disease_ontology
id: DOID:10272

heart conduction disease
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Class
    union of: Restriction
      on property: realized in
      some values from: Class
        intersection of: disease course
        intersection of: Restriction
    union of: Restriction
      on property: has material basis at all times
      some values from: heart conduction disorder
CVDO definition: A disease affecting the conducting tissue of the heart.
definition: A heart disease that involves the heart's electrical conduction system.
imported from: doid.owl
database_cross_reference: ICD9CM:426.6
database_cross_reference: SNOMEDCT_2010_1_31:195053008
database_cross_reference: SNOMEDCT_2010_1_31:195056000
database_cross_reference: UMLS_CUI:C0029630
has_obo_namespace: disease_ontology
id: DOID:10273

Raynaud disease
type: Class
subclass of: peripheral vascular disease
imported from: doid.owl
database_cross_reference: ICD9CM:443.0
database_cross_reference: MSH:D011928
database_cross_reference: NCI:C34972
database_cross_reference: OMIM:179600
database_cross_reference: SNOMEDCT_2010_1_31:123266007
database_cross_reference: SNOMEDCT_2010_1_31:155429004
database_cross_reference: SNOMEDCT_2010_1_31:195294005
database_cross_reference: SNOMEDCT_2010_1_31:195295006
database_cross_reference: SNOMEDCT_2010_1_31:195297003
database_cross_reference: SNOMEDCT_2010_1_31:22954002
database_cross_reference: SNOMEDCT_2010_1_31:266319002
database_cross_reference: UMLS_CUI:C0034734
has_exact_synonym: Raynaud's disease
has_exact_synonym: Raynaud's disease (disorder)
has_exact_synonym: Raynaud's syndrome
has_exact_synonym: Raynaud's syndrome (disorder)
has_exact_synonym: Raynaud's syndrome (disorder) [Ambiguous]
has_exact_synonym: Raynaud's syndrome NOS (disorder)
has_obo_namespace: disease_ontology
id: DOID:10300
comment: OMIM mapping confirmed by DO. [SN].

endocarditis
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: inflammation process in an endocardium
CVDO definition: A disease characterized by an inflammation of the endocardium.
definition: A heart disease involving non-infectious inflammation of the endocardium (inner layer of the heart).
imported from: doid.owl
has_alternative_id: DOID:14058
database_cross_reference: MSH:D004696
database_cross_reference: NCI:C34582
database_cross_reference: SNOMEDCT_2010_1_31:194935007
database_cross_reference: SNOMEDCT_2010_1_31:56819008
database_cross_reference: SNOMEDCT_2010_1_31:91357005
database_cross_reference: UMLS_CUI:C0014118
database_cross_reference: UMLS_CUI:C0375268
has_obo_namespace: disease_ontology
id: DOID:10314

anomalous atrioventricular excitation (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: anomalous atrioventricular excitation (process)
CVDO editor note: DOID label 'anomalous atrioventricular excitation' was changed.
imported from: doid.owl
database_cross_reference: ICD9CM:426.7
database_cross_reference: SNOMEDCT_2010_1_31:155360000
database_cross_reference: SNOMEDCT_2010_1_31:17869006
database_cross_reference: SNOMEDCT_2010_1_31:195057009
database_cross_reference: SNOMEDCT_2010_1_31:195061003
database_cross_reference: SNOMEDCT_2010_1_31:266304003
database_cross_reference: UMLS_CUI:C0392470
has_exact_synonym: Anomalous A-V excitation
has_obo_namespace: disease_ontology
id: DOID:10392

Dressler's syndrome
type: Class
subclass of: pericarditis
imported from: doid.owl
database_cross_reference: ICD9CM:411.0
database_cross_reference: SNOMEDCT_2010_1_31:66189004
database_cross_reference: UMLS_CUI:C0152107
has_exact_synonym: Postmyocardial infarction syndrome
has_exact_synonym: Postmyocardial infarction syndrome (disorder)
has_obo_namespace: disease_ontology
id: DOID:10507

supine hypotensive syndrome
type: Class
subclass of: compression disease
imported from: doid.owl
has_alternative_id: DOID:10555
has_alternative_id: DOID:12413
database_cross_reference: ICD9CM:669.20
database_cross_reference: UMLS_CUI:C0157456
has_exact_synonym: antepartum maternal hypotension syndrome
has_exact_synonym: postpartum maternal hypotension syndrome
has_obo_namespace: disease_ontology
id: DOID:10556

mild pre-eclampsia
type: Class
subclass of: pre-eclampsia
imported from: doid.owl
database_cross_reference: ICD9CM:642.40
database_cross_reference: UMLS_CUI:C0156664
has_obo_namespace: disease_ontology
id: DOID:10590

pre-eclampsia
type: Class
subclass of: vascular disease - unclassified by CVDO
imported from: doid.owl
has_alternative_id: DOID:12684
database_cross_reference: MSH:D011225
database_cross_reference: NCI:C34943
database_cross_reference: NCI:C85021
database_cross_reference: OMIM:189800
database_cross_reference: OMIM:609404
database_cross_reference: SNOMEDCT_2010_1_31:15394000
database_cross_reference: SNOMEDCT_2010_1_31:156106005
database_cross_reference: SNOMEDCT_2010_1_31:156109003
database_cross_reference: SNOMEDCT_2010_1_31:156112000
database_cross_reference: SNOMEDCT_2010_1_31:198969004
database_cross_reference: SNOMEDCT_2010_1_31:198972006
database_cross_reference: SNOMEDCT_2010_1_31:198979002
database_cross_reference: SNOMEDCT_2010_1_31:199011002
database_cross_reference: SNOMEDCT_2010_1_31:237280005
database_cross_reference: SNOMEDCT_2010_1_31:267306006
database_cross_reference: SNOMEDCT_2010_1_31:267307002
database_cross_reference: SNOMEDCT_2010_1_31:288201007
database_cross_reference: SNOMEDCT_2010_1_31:30354006
database_cross_reference: SNOMEDCT_2010_1_31:308551004
database_cross_reference: SNOMEDCT_2010_1_31:398254007
database_cross_reference: SNOMEDCT_2010_1_31:46764007
database_cross_reference: SNOMEDCT_2010_1_31:48194001
database_cross_reference: SNOMEDCT_2010_1_31:6758009
database_cross_reference: UMLS_CUI:C0032914
database_cross_reference: UMLS_CUI:C0340274
has_exact_synonym: Gestational hypertension
has_exact_synonym: Gestational hypertension (disorder)
has_exact_synonym: PREECLAMPSIA/ECLAMPSIA
has_exact_synonym: Pre-eclampsia (disorder)
has_exact_synonym: Pre-eclampsia NOS
has_exact_synonym: Pre-eclampsia NOS (disorder)
has_exact_synonym: Pre-eclamptic NOS
has_exact_synonym: Pre-eclamptic toxaemia
has_exact_synonym: Pregnancy associated hypertension
has_exact_synonym: Pregnancy-induced hypertension (disorder)
has_exact_synonym: Proteinuric hypertension of pregnancy
has_exact_synonym: Toxaemia NOS
has_exact_synonym: Toxaemia of pregnancy
has_exact_synonym: Toxemia NOS (disorder)
has_exact_synonym: Toxemia of Pregnancy
has_exact_synonym: Toxemia of pregnancy (disorder)
has_exact_synonym: hypertension induced by pregnancy
has_exact_synonym: hypertension of preg.
has_exact_synonym: hypertension of pregnancy NOS
has_exact_synonym: hypertension of pregnancy NOS (disorder)
has_exact_synonym: preeclampsia
has_exact_synonym: pregnancy toxemia
has_obo_namespace: disease_ontology
id: DOID:10591
comment: OMIM mapping confirmed by DO. [SN].

allergic urticaria
type: Class
subclass of: urticaria
imported from: doid.owl
database_cross_reference: ICD9CM:708.0
database_cross_reference: SNOMEDCT_2010_1_31:156428000
database_cross_reference: SNOMEDCT_2010_1_31:201260002
database_cross_reference: SNOMEDCT_2010_1_31:40178009
database_cross_reference: UMLS_CUI:C0149526
has_exact_synonym: Allergic urticaria (disorder)
has_obo_namespace: disease_ontology
id: DOID:10612

acute inferoposterior infarction
type: Class
subclass of: acute myocardial infarction
imported from: doid.owl
database_cross_reference: ICD9CM:410.30
database_cross_reference: UMLS_CUI:C0155640
has_obo_namespace: disease_ontology
id: DOID:10648

acute inferolateral myocardial infarction
type: Class
subclass of: acute myocardial infarction
imported from: doid.owl
database_cross_reference: ICD9CM:410.20
database_cross_reference: UMLS_CUI:C0155636
has_obo_namespace: disease_ontology
id: DOID:10649

acute anterolateral myocardial infarction
type: Class
subclass of: acute myocardial infarction
imported from: doid.owl
database_cross_reference: ICD9CM:410.0
database_cross_reference: SNOMEDCT_2010_1_31:70211005
database_cross_reference: UMLS_CUI:C0155627
has_obo_namespace: disease_ontology
id: DOID:10651

renal hypertension
type: Class
subclass of: secondary hypertension
imported from: doid.owl
database_cross_reference: MSH:D006977
database_cross_reference: NCI:C3121
database_cross_reference: SNOMEDCT_2010_1_31:194775007
database_cross_reference: SNOMEDCT_2010_1_31:28119000
database_cross_reference: UMLS_CUI:C0020544
has_obo_namespace: disease_ontology
id: DOID:1073

portal hypertension
type: Class
subclass of: hepatic vascular disease
imported from: doid.owl
database_cross_reference: ICD9CM:572.3
database_cross_reference: MSH:D006975
database_cross_reference: NCI:C3119
database_cross_reference: SNOMEDCT_2010_1_31:155821005
database_cross_reference: SNOMEDCT_2010_1_31:34742003
database_cross_reference: UMLS_CUI:C0020541
has_obo_namespace: disease_ontology
id: DOID:10762

hypertension
type: Class
subclass of: disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: highly pressured arterial blood flow
imported from: doid.owl
database_cross_reference: ICD9CM:401-405.99
database_cross_reference: ICD9CM:997.91
database_cross_reference: MSH:D006973
database_cross_reference: NCI:C3117
database_cross_reference: SNOMEDCT_2010_1_31:155295004
database_cross_reference: SNOMEDCT_2010_1_31:155302005
database_cross_reference: SNOMEDCT_2010_1_31:194756002
database_cross_reference: SNOMEDCT_2010_1_31:194757006
database_cross_reference: SNOMEDCT_2010_1_31:194760004
database_cross_reference: SNOMEDCT_2010_1_31:194794002
database_cross_reference: SNOMEDCT_2010_1_31:195537001
database_cross_reference: SNOMEDCT_2010_1_31:266287006
database_cross_reference: SNOMEDCT_2010_1_31:38341003
database_cross_reference: UMLS_CUI:C0020538
has_exact_synonym: HTN
has_exact_synonym: High blood pressure (& [essential hypertension])
has_exact_synonym: hyperpiesia
has_exact_synonym: vascular hypertensive disorder
has_obo_namespace: disease_ontology
has_related_synonym: hypertensive disease
id: DOID:10763

fiedler's myocarditis
type: Class
subclass of: acute myocarditis
imported from: doid.owl
database_cross_reference: ICD9CM:422.91
database_cross_reference: SNOMEDCT_2010_1_31:194954007
database_cross_reference: SNOMEDCT_2010_1_31:194955008
database_cross_reference: SNOMEDCT_2010_1_31:266238009
database_cross_reference: SNOMEDCT_2010_1_31:91025000
database_cross_reference: UMLS_CUI:C0155689
has_exact_synonym: Idiopathic myocarditis
has_exact_synonym: Idiopathic myocarditis (disorder)
has_exact_synonym: Idiopathic myocarditis NOS (disorder)
has_exact_synonym: Isolated (Fiedler's) myocarditis
has_exact_synonym: Isolated (Fiedler's) myocarditis (disorder)
has_obo_namespace: disease_ontology
id: DOID:10778

septic myocarditis
type: Class
subclass of: acute myocarditis
imported from: doid.owl
database_cross_reference: ICD9CM:422.92
database_cross_reference: SNOMEDCT_2010_1_31:194959002
database_cross_reference: SNOMEDCT_2010_1_31:64043005
database_cross_reference: UMLS_CUI:C0155690
has_exact_synonym: Septic myocarditis NOS (disorder)
has_exact_synonym: Septic myocarditis, NOS
has_obo_namespace: disease_ontology
id: DOID:10779

malignant essential hypertension
type: Class
subclass of: malignant hypertension
subclass of: essential hypertension
imported from: doid.owl
database_cross_reference: ICD9CM:401.0
database_cross_reference: NCI:C34802
database_cross_reference: SNOMEDCT_2010_1_31:1218009
database_cross_reference: SNOMEDCT_2010_1_31:78975002
database_cross_reference: UMLS_CUI:C0024588
has_exact_synonym: Accelerated essential hypertension
has_exact_synonym: malignant Essential hypertension
has_exact_synonym: malignant essential hypertension (disorder)
has_obo_namespace: disease_ontology
id: DOID:10823

malignant hypertension
type: Class
subclass of: hypertension
imported from: doid.owl
database_cross_reference: MSH:D006974
database_cross_reference: NCI:C3118
database_cross_reference: SNOMEDCT_2010_1_31:155301003
database_cross_reference: SNOMEDCT_2010_1_31:286951002
database_cross_reference: SNOMEDCT_2010_1_31:70272006
database_cross_reference: UMLS_CUI:C0020540
has_exact_synonym: malignant hypertension
has_exact_synonym: malignant hypertension (disorder)
has_obo_namespace: disease_ontology
id: DOID:10824

essential hypertension
type: Class
subclass of: hypertension
imported from: doid.owl
database_cross_reference: ICD9CM:401
database_cross_reference: ICD9CM:401.9
database_cross_reference: NCI:C3478
database_cross_reference: OMIM:145500
database_cross_reference: SNOMEDCT_2010_1_31:155296003
database_cross_reference: SNOMEDCT_2010_1_31:194757006
database_cross_reference: SNOMEDCT_2010_1_31:194760004
database_cross_reference: SNOMEDCT_2010_1_31:266228004
database_cross_reference: SNOMEDCT_2010_1_31:59621000
database_cross_reference: UMLS_CUI:C0085580
has_exact_synonym: Essential hypertension
has_exact_synonym: Essential hypertension (disorder)
has_exact_synonym: Essential hypertension NOS
has_exact_synonym: Essential hypertension NOS (disorder)
has_exact_synonym: Unspecified essential hypertension
has_exact_synonym: idiopathic hypertension
has_exact_synonym: primary hypertension
has_obo_namespace: disease_ontology
id: DOID:10825
comment: OMIM mapping confirmed by DO. [SN].

iliac vein thrombophlebitis
type: Class
subclass of: thrombophlebitis
imported from: doid.owl
database_cross_reference: ICD9CM:451.81
database_cross_reference: SNOMEDCT_2010_1_31:195429006
database_cross_reference: UMLS_CUI:C0155772
has_exact_synonym: Phlebitis and thrombophlebitis of the iliac vein NOS (disorder)
has_obo_namespace: disease_ontology
id: DOID:10880

benign essential hypertension
type: Class
subclass of: essential hypertension
imported from: doid.owl
database_cross_reference: ICD9CM:401.1
database_cross_reference: NCI:C3656
database_cross_reference: SNOMEDCT_2010_1_31:1201005
database_cross_reference: SNOMEDCT_2010_1_31:194758001
database_cross_reference: UMLS_CUI:C0155583
has_exact_synonym: benign Essential hypertension
has_exact_synonym: benign essential hypertension (disorder)
has_obo_namespace: disease_ontology
id: DOID:10913

intracranial aneurysm
type: Class
subclass of: aneurysm (disease)
imported from: doid.owl
database_cross_reference: MSH:D002532
database_cross_reference: NCI:C34458
database_cross_reference: SNOMEDCT_2010_1_31:128609009
database_cross_reference: SNOMEDCT_2010_1_31:42994005
database_cross_reference: UMLS_CUI:C0007766
has_exact_synonym: intracranial aneurysm
has_exact_synonym: intracranial aneurysm (disorder)
has_exact_synonym: intracranial aneurysm, NOS
has_obo_namespace: disease_ontology
id: DOID:10941
label: intracranial aneurysm disease

basal ganglia cerebrovascular disease
type: Class
subclass of: cerebrovascular disease
imported from: doid.owl
database_cross_reference: MSH:D020144
database_cross_reference: UMLS_CUI:C0751739
has_obo_namespace: disease_ontology
id: DOID:10991

secondary hypertension
type: Class
subclass of: hypertension
imported from: doid.owl
database_cross_reference: ICD9CM:405
database_cross_reference: ICD9CM:405.9
database_cross_reference: NCI:C3657
database_cross_reference: SNOMEDCT_2010_1_31:155300002
database_cross_reference: SNOMEDCT_2010_1_31:194789002
database_cross_reference: SNOMEDCT_2010_1_31:194792003
database_cross_reference: SNOMEDCT_2010_1_31:31992008
database_cross_reference: UMLS_CUI:C0155616
has_obo_namespace: disease_ontology
id: DOID:11130

ruptured thoracoabdominal aortic aneurysm
type: Class
subclass of: ruptured thoracic aortic aneurysm
imported from: doid.owl
database_cross_reference: ICD9CM:441.6
database_cross_reference: SNOMEDCT_2010_1_31:195265003
database_cross_reference: UMLS_CUI:C1305122
has_exact_synonym: Thoracoabdominal aortic aneurysm, ruptured (disorder)
has_obo_namespace: disease_ontology
id: DOID:11138
label: ruptured thoracoabdominal aortic aneurysm disease

esophageal varix
type: Class
subclass of: vein disorder
imported from: doid.owl
has_alternative_id: DOID:111
has_alternative_id: DOID:13536
has_alternative_id: DOID:14031
database_cross_reference: ICD9CM:456.0
database_cross_reference: NCI:C78282
database_cross_reference: SNOMEDCT_2010_1_31:17709002
database_cross_reference: SNOMEDCT_2010_1_31:195474004
database_cross_reference: SNOMEDCT_2010_1_31:195475003
database_cross_reference: SNOMEDCT_2010_1_31:195479009
database_cross_reference: SNOMEDCT_2010_1_31:195643006
database_cross_reference: SNOMEDCT_2010_1_31:236067006
database_cross_reference: UMLS_CUI:C0155789
database_cross_reference: UMLS_CUI:C0155791
database_cross_reference: UMLS_CUI:C0155792
has_exact_synonym: Bleeding esophageal varices
has_exact_synonym: Bleeding esophageal varices (disorder)
has_exact_synonym: Bleeding oesophageal varices
has_exact_synonym: esophageal varices
has_exact_synonym: esophageal varices in disease classified elsewhere, with bleeding
has_exact_synonym: esophageal varices with bleeding
has_exact_synonym: esophageal varices with bleeding in disease EC (disorder)
has_exact_synonym: esophageal varices without bleeding
has_exact_synonym: esophageal varices without bleeding (disorder)
has_exact_synonym: esophageal varices without mention of bleeding
has_obo_namespace: disease_ontology
id: DOID:112

vertebral artery occlusion
type: Class
subclass of: occlusion precerebral artery
imported from: doid.owl
database_cross_reference: ICD9CM:433.2
database_cross_reference: UMLS_CUI:C0155724
has_exact_synonym: Occlusion and stenosis of vertebral artery
has_obo_namespace: disease_ontology
id: DOID:11299

Mobitz II second degree atrioventricular block (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: Mobitz II second degree atrioventricular block (process)
CVDO editor note: DOID label changed for homogeneization reasons.
imported from: doid.owl
database_cross_reference: ICD9CM:426.12
database_cross_reference: NCI:C62018
database_cross_reference: SNOMEDCT_2010_1_31:28189009
database_cross_reference: UMLS_CUI:C0155700
has_exact_synonym: Mobitz (type) II atrioventricular block
has_exact_synonym: Mobitz II atrioventricular block
has_exact_synonym: Mobitz type II atrioventricular block
has_exact_synonym: Mobitz type II atrioventricular block (disorder)
has_obo_namespace: disease_ontology
id: DOID:11312

cerebral arteritis
type: Class
subclass of: cerebrovascular disease
imported from: doid.owl
database_cross_reference: ICD9CM:437.4
database_cross_reference: SNOMEDCT_2010_1_31:28366008
database_cross_reference: UMLS_CUI:C0007773
has_exact_synonym: Cerebral arteritis (disorder)
has_obo_namespace: disease_ontology
id: DOID:11390

heart disease
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Class
    union of: Restriction
      on property: realized in
      some values from: Class
        intersection of: disease course
        intersection of: Restriction
    union of: Restriction
      on property: has material basis at all times
      some values from: heart disorder
CVDO definition: A disease affecting the heart.
definition: A cardiovascular system disease that involves the heart or blood vessels (arteries and veins).
imported from: doid.owl
database_cross_reference: ICD9CM:429.9
database_cross_reference: MSH:D006331
database_cross_reference: NCI:C3079
database_cross_reference: SNOMEDCT_2010_1_31:155263000
database_cross_reference: SNOMEDCT_2010_1_31:194707003
database_cross_reference: SNOMEDCT_2010_1_31:195152001
database_cross_reference: SNOMEDCT_2010_1_31:266275004
database_cross_reference: SNOMEDCT_2010_1_31:266311004
database_cross_reference: SNOMEDCT_2010_1_31:56265001
database_cross_reference: UMLS_CUI:C0018799
has_obo_namespace: disease_ontology
id: DOID:114

pseudotumor cerebri
type: Class
subclass of: cerebrovascular disease
subclass of: intracranial hypertension
imported from: doid.owl
database_cross_reference: ICD9CM:348.2
database_cross_reference: MSH:D011559
database_cross_reference: NCI:C85035
database_cross_reference: OMIM:243200
database_cross_reference: SNOMEDCT_2010_1_31:155052007
database_cross_reference: SNOMEDCT_2010_1_31:267701004
database_cross_reference: SNOMEDCT_2010_1_31:68267002
database_cross_reference: UMLS_CUI:C0033845
has_exact_synonym: Pseudotumor cerebri
has_exact_synonym: benign intracran. hypt.
has_exact_synonym: benign intracranial hypertension
has_exact_synonym: benign intracranial hypertension (disorder)
has_exact_synonym: idiopathic intracranial hypertension
has_obo_namespace: disease_ontology
id: DOID:11459
comment: OMIM mapping confirmed by DO. [SN].

constrictive pericarditis
type: Class
subclass of: pericarditis
imported from: doid.owl
database_cross_reference: ICD9CM:423.2
database_cross_reference: MSH:D010494
database_cross_reference: NCI:C78246
database_cross_reference: SNOMEDCT_2010_1_31:155340008
database_cross_reference: SNOMEDCT_2010_1_31:194969008
database_cross_reference: SNOMEDCT_2010_1_31:85598007
database_cross_reference: UMLS_CUI:C0031048
has_exact_synonym: Constrictive pericarditis
has_exact_synonym: Constrictive pericarditis (disorder)
has_exact_synonym: Constrictive pericarditis NOS (disorder)
has_obo_namespace: disease_ontology
id: DOID:11481

hemopericardium
type: Class
subclass of: disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: fluid accumulation in the pericardial cavity
definition: A pericardial effusion that results from blood in the pericardial sac.
imported from: doid.owl
database_cross_reference: ICD9CM:423.0
database_cross_reference: MSH:D010490
database_cross_reference: SNOMEDCT_2010_1_31:155339006
database_cross_reference: SNOMEDCT_2010_1_31:23412002
database_cross_reference: UMLS_CUI:C0019064
has_exact_synonym: Haemopericardium
has_obo_namespace: disease_ontology
id: DOID:11482

cardiac tamponade
type: Class
subclass of: disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: heart pathological process
subclass of: Restriction
  on property: has material basis at all times
  some values from: fluid in the pericardial cavity
CVDO definition: A disease caused by the presence of fluid in the pericardial cavity (due to pericardial effusion), affecting negatively the heart's pumping function.
CVDO editor note: In CVDO, cardiac tamponade is defined as *being caused* by a pericardial effusion, rather than as *being* a pericardial effusion.
definition: A pericardial effusion in which fluid accumulates in the pericardium (the sac in which the heart is enclosed) and the pericardial spaces fills up faster than the pericardial sac can stretch.
imported from: doid.owl
database_cross_reference: ICD9CM:423.3
database_cross_reference: MSH:D002305
database_cross_reference: NCI:C50481
database_cross_reference: SNOMEDCT_2010_1_31:155341007
database_cross_reference: SNOMEDCT_2010_1_31:194975004
database_cross_reference: SNOMEDCT_2010_1_31:266295005
database_cross_reference: SNOMEDCT_2010_1_31:35304003
database_cross_reference: UMLS_CUI:C0007177
has_exact_synonym: Rose's tamponade
has_exact_synonym: pericardial tamponade
has_obo_namespace: disease_ontology
id: DOID:115

mitral valve insufficiency
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: mitral valve improper close during left ventricular systole
  intersection of: Restriction
    on property: has material basis at all times
    some values from: mitral valve disorder
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: retrograd blood flow through mitral valve during left ventricular systole
CVDO definition: A disease in which an abnormal structure in a mitral valve prevents it to close propertly during systole, occasioning a retrograd blood flow through the valve.
imported from: doid.owl
has_alternative_id: DOID:11737
database_cross_reference: MSH:D008944
database_cross_reference: NCI:C50852
database_cross_reference: NCI:C50888
database_cross_reference: SNOMEDCT_2010_1_31:194736003
database_cross_reference: SNOMEDCT_2010_1_31:194977007
database_cross_reference: SNOMEDCT_2010_1_31:48724000
database_cross_reference: SNOMEDCT_2010_1_31:59464004
database_cross_reference: UMLS_CUI:C0026266
database_cross_reference: UMLS_CUI:C0264774
has_exact_synonym: Mitral valve incompetence
has_exact_synonym: mitral regurgitation
has_obo_namespace: disease_ontology
id: DOID:11502

rheumatic disease of mitral valve
type: Class
subclass of: mitral valve disease
imported from: doid.owl
database_cross_reference: ICD9CM:394
database_cross_reference: SNOMEDCT_2010_1_31:155276006
database_cross_reference: SNOMEDCT_2010_1_31:194724009
database_cross_reference: SNOMEDCT_2010_1_31:250998008
database_cross_reference: SNOMEDCT_2010_1_31:266278002
database_cross_reference: SNOMEDCT_2010_1_31:286947004
database_cross_reference: SNOMEDCT_2010_1_31:83898004
database_cross_reference: UMLS_CUI:C0264765
has_exact_synonym: Mitral RH valve dis.
has_exact_synonym: Mitral valve disease
has_exact_synonym: Rheumatic disease of mitral valve (disorder)
has_exact_synonym: Rheumatic mitral valve changes
has_exact_synonym: chronic rheumatic mitral valve (disorder)
has_exact_synonym: disease of mitral valve
has_obo_namespace: disease_ontology
id: DOID:11505

hepatic vein thrombosis
type: Class
subclass of: hepatic vascular disease
imported from: doid.owl
database_cross_reference: MSH:D006502
database_cross_reference: SNOMEDCT_2010_1_31:195436007
database_cross_reference: SNOMEDCT_2010_1_31:38739001
database_cross_reference: UMLS_CUI:C0019154
has_exact_synonym: Budd - Chiari syndrome (hepatic vein thrombosis)
has_exact_synonym: Budd-Chiari syndrome
has_exact_synonym: Budd-Chiari syndrome (disorder)
has_exact_synonym: hepatic vein thrombosis
has_exact_synonym: hepatic vein thrombosis (disorder)
has_obo_namespace: disease_ontology
id: DOID:11512

hypertensive heart disease
type: Class
subclass of: disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: heart pathological process
definition: A heart disease that is caused by high blood presure.
imported from: doid.owl
database_cross_reference: ICD9CM:402
database_cross_reference: ICD9CM:402.9
database_cross_reference: SNOMEDCT_2010_1_31:155297007
database_cross_reference: SNOMEDCT_2010_1_31:194769003
database_cross_reference: SNOMEDCT_2010_1_31:194772005
database_cross_reference: SNOMEDCT_2010_1_31:64715009
database_cross_reference: UMLS_CUI:C0152105
has_obo_namespace: disease_ontology
id: DOID:11516

benign hypertensive renal disease
type: Class
subclass of: renal hypertension
imported from: doid.owl
database_cross_reference: ICD9CM:403.1
database_cross_reference: ICD9CM:403.10
database_cross_reference: SNOMEDCT_2010_1_31:193003
database_cross_reference: UMLS_CUI:C0155596
has_exact_synonym: benign hypertensive renal disease (disorder)
has_exact_synonym: hypertensive renal disease, benign
has_exact_synonym: hypertensive renal disease, benign, without mention of renal failure
has_obo_namespace: disease_ontology
id: DOID:11520

retinal vasculitis
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: inflammation process in a retinal artery
CVDO definition: A disease characterized by an inflammation of a retinal artery.
imported from: doid.owl
database_cross_reference: ICD9CM:362.18
database_cross_reference: MSH:D031300
database_cross_reference: SNOMEDCT_2010_1_31:193367006
database_cross_reference: SNOMEDCT_2010_1_31:77628002
database_cross_reference: UMLS_CUI:C0152026
has_exact_synonym: Retinal vasculitis
has_exact_synonym: Retinal vasculitis (disorder)
has_exact_synonym: Retinal vasculitis NOS (disorder)
has_obo_namespace: disease_ontology
id: DOID:11563

nephrosclerosis
type: Class
subclass of: renal hypertension
subclass of: renal vascular disease
imported from: doid.owl
database_cross_reference: ICD9CM:587
database_cross_reference: MSH:D009400
database_cross_reference: SNOMEDCT_2010_1_31:194773000
database_cross_reference: SNOMEDCT_2010_1_31:197658002
database_cross_reference: SNOMEDCT_2010_1_31:197662008
database_cross_reference: SNOMEDCT_2010_1_31:32916005
database_cross_reference: UMLS_CUI:C0027719
has_exact_synonym: Nephrosclerosis (disorder)
has_exact_synonym: nephrosclerosis
has_exact_synonym: renal sclerosis
has_exact_synonym: renal sclerosis NOS (disorder)
has_exact_synonym: renal sclerosis unspecified (disorder)
has_exact_synonym: renal sclerosis, unspecified
has_obo_namespace: disease_ontology
id: DOID:11664

portal vein thrombosis
type: Class
equivalent class: Class
  intersection of: thrombosis
  intersection of: Restriction
    on property: occurs in
    some values from: Portal vein
CVDO definition: A thrombosis that occurs in a portal vein.
imported from: doid.owl
database_cross_reference: ICD9CM:452
database_cross_reference: NCI:C78565
database_cross_reference: SNOMEDCT_2010_1_31:155455003
database_cross_reference: SNOMEDCT_2010_1_31:17920008
database_cross_reference: UMLS_CUI:C0155773
has_obo_namespace: disease_ontology
id: DOID:11695

diabetic angiopathy
type: Class
subclass of: ischemic disease
imported from: doid.owl
database_cross_reference: MSH:D003925
database_cross_reference: NCI:C35610
database_cross_reference: UMLS_CUI:C0011875
has_exact_synonym: Diabetic vascular disorder
has_exact_synonym: diabetic angiopathy
has_obo_namespace: disease_ontology
id: DOID:11713

pericardial effusion
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: fluid accumulation in the pericardial cavity
definition: A heart disease that is characterized by an abnormal accumulation of fluid in the pericardial cavity.
imported from: doid.owl
database_cross_reference: MSH:D010490
database_cross_reference: NCI:C3319
database_cross_reference: SNOMEDCT_2010_1_31:373945007
database_cross_reference: SNOMEDCT_2010_1_31:70370001
database_cross_reference: UMLS_CUI:C0031039
has_obo_namespace: disease_ontology
id: DOID:118

coronary artery vasospasm
type: Class
equivalent class: Class
  intersection of: coronary heart disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: coronary artery smooth muscle constriction
CVDO definition: A coronary heart disease with coronary artery smooth muscle constriction.
imported from: doid.owl
database_cross_reference: MSH:D003329
database_cross_reference: NCI:C34515
database_cross_reference: SNOMEDCT_2010_1_31:23687008
database_cross_reference: UMLS_CUI:C0010073
has_exact_synonym: Coronary Vasospasm
has_exact_synonym: Coronary artery spasm (disorder)
has_obo_namespace: disease_ontology
id: DOID:11840

coronary artery anomaly
type: Class
subclass of: coronary arteriosclerosis
imported from: doid.owl
database_cross_reference: ICD9CM:746.85
database_cross_reference: SNOMEDCT_2010_1_31:204373000
database_cross_reference: SNOMEDCT_2010_1_31:204380003
database_cross_reference: SNOMEDCT_2010_1_31:28574005
database_cross_reference: SNOMEDCT_2010_1_31:361215006
database_cross_reference: UMLS_CUI:C0158623
has_exact_synonym: Congenital anomaly of coronary artery (disorder)
has_exact_synonym: Coronary artery abnormality (disorder)
has_exact_synonym: Coronary artery abnormality [Ambiguous]
has_exact_synonym: Coronary artery anomaly NOS (disorder)
has_exact_synonym: Coronary artery anomaly, congenital
has_obo_namespace: disease_ontology
id: DOID:11843

coronary thrombosis
type: Class
equivalent class: Class
  intersection of: thrombosis
  intersection of: Restriction
    on property: occurs in
    some values from: Coronary artery
CVDO definition: A thrombosis occuring in a coronary artery.
imported from: doid.owl
database_cross_reference: MSH:D003328
database_cross_reference: SNOMEDCT_2010_1_31:155304006
database_cross_reference: SNOMEDCT_2010_1_31:194796000
database_cross_reference: SNOMEDCT_2010_1_31:266288001
database_cross_reference: SNOMEDCT_2010_1_31:398274000
database_cross_reference: SNOMEDCT_2010_1_31:66514008
database_cross_reference: UMLS_CUI:C0010072
has_exact_synonym: Coronary artery thrombosis (disorder)
has_exact_synonym: Coronary thrombosis
has_exact_synonym: coronary thrombosis
has_obo_namespace: disease_ontology
id: DOID:11847

hypertrophic cardiomyopathy
type: Class
subclass of: disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: left ventricular myocardium hypertrophy
    intersection of: Restriction
      on property: has occurrent part
      some values from: left ventricular myocardium contraction dysfunctional process
CVDO definition: "A heart disease with increased ventricular wall thickness or mass in the absence of loading conditions (hypertension, valve disease) sufficient to cause the observed abnormality." (Elliott et al., 2008, European Heart Journal, 29, 270-276)
imported from: doid.owl
database_cross_reference: ICD9CM:425.1
database_cross_reference: MSH:D002312
database_cross_reference: NCI:C34449
database_cross_reference: OMIM:192600
database_cross_reference: SNOMEDCT_2010_1_31:15471000
database_cross_reference: SNOMEDCT_2010_1_31:155351008
database_cross_reference: SNOMEDCT_2010_1_31:233873004
database_cross_reference: SNOMEDCT_2010_1_31:266301006
database_cross_reference: SNOMEDCT_2010_1_31:389998005
database_cross_reference: SNOMEDCT_2010_1_31:389999002
database_cross_reference: SNOMEDCT_2010_1_31:45227007
database_cross_reference: UMLS_CUI:C0007194
has_exact_synonym: Cardiomyopathy, hypertrophic
has_exact_synonym: hyper. obst. cardiomyopathy
has_exact_synonym: hypertrophic cardiomyopathy
has_exact_synonym: hypertrophic cardiomyopathy (disorder)
has_exact_synonym: hypertrophic myocardiopathy
has_exact_synonym: hypertrophic obstructive cardiomyopathy
has_exact_synonym: hypertrophic obstructive cardiomyopathy (disorder)
has_exact_synonym: primary hypertrophic cardiomyopathy (disorder) [Ambiguous]
has_obo_namespace: disease_ontology
id: DOID:11984
comment: OMIM mapping confirmed by DO. [LS].

ischemic optic neuropathy
type: Class
subclass of: ischemic disease
imported from: doid.owl
database_cross_reference: ICD9CM:377.41
database_cross_reference: MSH:D018917
database_cross_reference: SNOMEDCT_2010_1_31:14357004
database_cross_reference: UMLS_CUI:C0155305
has_exact_synonym: Ischemic optic neuropathy
has_exact_synonym: Ischemic optic neuropathy (disorder)
has_obo_namespace: disease_ontology
id: DOID:12010

rheumatic aortic valve stenosis
type: Class
subclass of: aortic valve stenosis
imported from: doid.owl
database_cross_reference: ICD9CM:395.0
database_cross_reference: SNOMEDCT_2010_1_31:155282009
database_cross_reference: SNOMEDCT_2010_1_31:72011007
database_cross_reference: UMLS_CUI:C0155567
has_exact_synonym: Rheumatic aortic stenosis
has_exact_synonym: Rheumatic aortic stenosis (disorder)
has_exact_synonym: Rheumatic aortic valve stenosis
has_obo_namespace: disease_ontology
id: DOID:12034

femoral vein thrombophlebitis
type: Class
subclass of: thrombophlebitis
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: inflammation process in a femoral vein
imported from: doid.owl
database_cross_reference: ICD9CM:451.11
database_cross_reference: SNOMEDCT_2010_1_31:1748006
database_cross_reference: SNOMEDCT_2010_1_31:195410000
database_cross_reference: UMLS_CUI:C0265066
has_exact_synonym: Phlebitis and thrombophlebitis of femoral vein (deep) (superficial)
has_exact_synonym: Thrombophlebitis of deep femoral vein (disorder)
has_exact_synonym: Thrombophlebitis of the femoral vein (disorder)
has_obo_namespace: disease_ontology
id: DOID:12282

kyphoscoliotic heart disease
type: Class
subclass of: chronic pulmonary heart disease
CVDO definition: A chronic pulmonary heart disease caused by a kyphoscoliosis.
imported from: doid.owl
database_cross_reference: ICD9CM:416.1
database_cross_reference: SNOMEDCT_2010_1_31:194886003
database_cross_reference: SNOMEDCT_2010_1_31:45650007
database_cross_reference: UMLS_CUI:C0152102
has_exact_synonym: Kyphoscoliotic heart disease (disorder)
has_obo_namespace: disease_ontology
id: DOID:12325

chronic pulmonary heart disease
type: Class
equivalent class: Class
  intersection of: cor pulmonale
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: chronic disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: right ventricular myocardium hypertrophy
CVDO definition: A cor pulmonale that has a chronic disease course during which the right ventricle becomes hypertrophied.
imported from: doid.owl
database_cross_reference: ICD9CM:416.8
database_cross_reference: SNOMEDCT_2010_1_31:194887007
database_cross_reference: SNOMEDCT_2010_1_31:194889005
database_cross_reference: UMLS_CUI:C0155673
has_obo_namespace: disease_ontology
id: DOID:12326

varicocele
type: Class
subclass of: pelvic varices
imported from: doid.owl
database_cross_reference: ICD9CM:456.4
database_cross_reference: MSH:D014646
database_cross_reference: SNOMEDCT_2010_1_31:155480003
database_cross_reference: SNOMEDCT_2010_1_31:195480007
database_cross_reference: SNOMEDCT_2010_1_31:46871008
database_cross_reference: SNOMEDCT_2010_1_31:51070004
database_cross_reference: UMLS_CUI:C0042341
has_exact_synonym: Scrotal varices
has_exact_synonym: Scrotal varices (disorder)
has_exact_synonym: Varicocele (disorder)
has_exact_synonym: Varicocele [Ambiguous]
has_exact_synonym: varicocele
has_obo_namespace: disease_ontology
id: DOID:12337

capillary disease
type: Class
subclass of: vascular disease
imported from: doid.owl
database_cross_reference: ICD9CM:448
database_cross_reference: SNOMEDCT_2010_1_31:155446001
database_cross_reference: SNOMEDCT_2010_1_31:155449008
database_cross_reference: SNOMEDCT_2010_1_31:195250004
database_cross_reference: SNOMEDCT_2010_1_31:195380006
database_cross_reference: SNOMEDCT_2010_1_31:195390003
database_cross_reference: SNOMEDCT_2010_1_31:266324004
database_cross_reference: SNOMEDCT_2010_1_31:57223003
database_cross_reference: SNOMEDCT_2010_1_31:58729003
database_cross_reference: UMLS_CUI:C0155765
has_exact_synonym: disease of capillaries
has_obo_namespace: disease_ontology
id: DOID:1271

telangiectasis
type: Class
subclass of: vascular skin disease
imported from: doid.owl
database_cross_reference: MSH:D013684
database_cross_reference: NCI:C28194
database_cross_reference: SNOMEDCT_2010_1_31:112641009
database_cross_reference: SNOMEDCT_2010_1_31:155449008
database_cross_reference: SNOMEDCT_2010_1_31:247479008
database_cross_reference: SNOMEDCT_2010_1_31:266324004
database_cross_reference: SNOMEDCT_2010_1_31:276328002
database_cross_reference: UMLS_CUI:C0039446
has_exact_synonym: telangiectasia
has_obo_namespace: disease_ontology
id: DOID:1272

cerebral atherosclerosis
type: Class
subclass of: atherosclerosis
subclass of: cerebrovascular disease
imported from: doid.owl
database_cross_reference: ICD9CM:437.0
database_cross_reference: MSH:D002537
database_cross_reference: NCI:C34459
database_cross_reference: SNOMEDCT_2010_1_31:195220007
database_cross_reference: SNOMEDCT_2010_1_31:266258005
database_cross_reference: SNOMEDCT_2010_1_31:55382008
database_cross_reference: UMLS_CUI:C0007775
has_exact_synonym: Cerebral atherosclerosis
has_exact_synonym: Cerebral atherosclerosis (disorder)
has_obo_namespace: disease_ontology
id: DOID:12720

cardiovascular system disease
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Class
    union of: Restriction
      on property: realized in
      some values from: Class
        intersection of: disease course
        intersection of: Restriction
    union of: Restriction
      on property: has material basis at all times
      some values from: cardiovascular system disorder
subclass of: disease
CVDO definition: A disease affecting the cardiovascular system.
definition: A disease of anatomical entity which occurs in the blood, heart, blood vessels or the lymphatic system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells or lymph to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis.
imported from: doid.owl
has_alternative_id: DOID:73
database_cross_reference: ICD9CM:429.2
database_cross_reference: MSH:D002318
database_cross_reference: NCI:C2931
database_cross_reference: SNOMEDCT_2010_1_31:105980002
database_cross_reference: SNOMEDCT_2010_1_31:155263000
database_cross_reference: SNOMEDCT_2010_1_31:194707003
database_cross_reference: SNOMEDCT_2010_1_31:195139006
database_cross_reference: SNOMEDCT_2010_1_31:195594006
database_cross_reference: SNOMEDCT_2010_1_31:266275004
database_cross_reference: SNOMEDCT_2010_1_31:266336005
database_cross_reference: SNOMEDCT_2010_1_31:49601007
database_cross_reference: UMLS_CUI:C0007222
has_exact_synonym: cardiovascular system disease
has_exact_synonym: disease of subdivision of hemolymphoid system
has_obo_namespace: disease_ontology
id: DOID:1287

thromboangiitis obliterans
type: Class
subclass of: arterial occlusive disease
subclass of: peripheral vascular disease
imported from: doid.owl
database_cross_reference: ICD9CM:443.1
database_cross_reference: MSH:D013919
database_cross_reference: NCI:C35070
database_cross_reference: OMIM:211480
database_cross_reference: SNOMEDCT_2010_1_31:155432001
database_cross_reference: SNOMEDCT_2010_1_31:195298008
database_cross_reference: SNOMEDCT_2010_1_31:195299000
database_cross_reference: SNOMEDCT_2010_1_31:195300008
database_cross_reference: SNOMEDCT_2010_1_31:52403007
database_cross_reference: UMLS_CUI:C0040021
has_exact_synonym: Buerger's disease
has_exact_synonym: Presenile gangrene
has_exact_synonym: Presenile gangrene (disorder)
has_exact_synonym: Thromboangiitis obliterans
has_exact_synonym: Thromboangiitis obliterans (disorder)
has_exact_synonym: Thromboangiitis obliterans NOS (disorder)
has_exact_synonym: Thromboangiitis obliterans [Buerger's disease]
has_obo_namespace: disease_ontology
id: DOID:12918
comment: OMIM mapping confirmed by DO. [LS].

endocardial fibroelastosis
type: Class
subclass of: disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: endocardium thickening
CVDO definition: A heart disease in which the endocardium thickens by increase in the amount of supporting connective tissue and elastic fibers. It is usually associated with children two years old and younger. Its etiological cause is unknown.
imported from: doid.owl
database_cross_reference: ICD9CM:425.3
database_cross_reference: MSH:D004695
database_cross_reference: OMIM:226000
database_cross_reference: OMIM:305300
database_cross_reference: SNOMEDCT_2010_1_31:65457005
database_cross_reference: UMLS_CUI:C0014117
has_exact_synonym: Elastomyofibrosis
has_exact_synonym: Endocardial fibroelastosis
has_exact_synonym: Endocardial fibroelastosis (disorder)
has_exact_synonym: endocardial fibroelastosis
has_obo_namespace: disease_ontology
id: DOID:12929
comment: OMIM mapping confirmed by DO. [SN].

dilated cardiomyopathy
type: Class
subclass of: disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: left ventricular myocardium dilatation
    intersection of: Restriction
      on property: has occurrent part
      some values from: left ventricular myocardium contraction dysfunctional process
CVDO definition: A cardiomyopathy characterized by left ventricular dilatation and left ventricular systolic dysfunction in the absence of abnormal loading conditions (hypertension, valve disease) or coronary heart disease sufficient to cause global systolic impairment. (adapted from Elliott et al., 2008, European Heart Journal, 29, 270-276)
definition: An intrinsic cardiomyopathy that results in damage to the myocardium causing the heart to pump blood inefficiently.
imported from: doid.owl
database_cross_reference: MSH:D002311
database_cross_reference: NCI:C84673
database_cross_reference: OMIM:115200
database_cross_reference: OMIM:300069
database_cross_reference: OMIM:302045
database_cross_reference: OMIM:601154
database_cross_reference: OMIM:601493
database_cross_reference: OMIM:601494
database_cross_reference: OMIM:604145
database_cross_reference: OMIM:604765
database_cross_reference: OMIM:605362
database_cross_reference: OMIM:606685
database_cross_reference: OMIM:607482
database_cross_reference: OMIM:607487
database_cross_reference: OMIM:608569
database_cross_reference: OMIM:609909
database_cross_reference: OMIM:611407
database_cross_reference: OMIM:611878
database_cross_reference: OMIM:611879
database_cross_reference: OMIM:611880
database_cross_reference: OMIM:612158
database_cross_reference: OMIM:612877
database_cross_reference: OMIM:613122
database_cross_reference: OMIM:613172
database_cross_reference: OMIM:613252
database_cross_reference: OMIM:613286
database_cross_reference: OMIM:613424
database_cross_reference: OMIM:613426
database_cross_reference: OMIM:613642
database_cross_reference: OMIM:613697
database_cross_reference: SNOMEDCT_2010_1_31:195018001
database_cross_reference: SNOMEDCT_2010_1_31:195021004
database_cross_reference: SNOMEDCT_2010_1_31:389995008
database_cross_reference: SNOMEDCT_2010_1_31:399020009
database_cross_reference: SNOMEDCT_2010_1_31:74368002
database_cross_reference: UMLS_CUI:C0007193
has_exact_synonym: Cardiomyopathy, congestive
has_exact_synonym: primary dilated cardiomyopathy (disorder)
has_obo_namespace: disease_ontology
has_related_synonym: Congestive cardiomyopathy
id: DOID:12930
comment: OMIM mapping confirmed by DO. [LS].

endomyocardial fibrosis
type: Class
subclass of: restrictive cardiomyopathy
CVDO definition: A restrictive cardiomyopathy which results in fibrous lesions of right and left ventricle. It occurs typically in tropical and subtropical Africa.
imported from: doid.owl
database_cross_reference: ICD9CM:425.0
database_cross_reference: MSH:D004719
database_cross_reference: NCI:C34585
database_cross_reference: SNOMEDCT_2010_1_31:111507009
database_cross_reference: SNOMEDCT_2010_1_31:123264005
database_cross_reference: SNOMEDCT_2010_1_31:155351008
database_cross_reference: SNOMEDCT_2010_1_31:266301006
database_cross_reference: SNOMEDCT_2010_1_31:30293000
database_cross_reference: SNOMEDCT_2010_1_31:398716006
database_cross_reference: UMLS_CUI:C0553980
has_exact_synonym: (Becker's disease) or (obscure African cardiomyopathy)
has_exact_synonym: African endomyocardial fibrosis
has_exact_synonym: Becker's disease
has_exact_synonym: Endomyocardial sclerosis
has_exact_synonym: Obscure African cardiomyopathy (disorder)
has_obo_namespace: disease_ontology
id: DOID:12932

alcoholic cardiomyopathy
type: Class
subclass of: dilated cardiomyopathy
CVDO definition: A dilated cardiomyopathy resulting from alcohol intoxication.
imported from: doid.owl
database_cross_reference: ICD9CM:425.5
database_cross_reference: MSH:D002310
database_cross_reference: NCI:C53653
database_cross_reference: SNOMEDCT_2010_1_31:155352001
database_cross_reference: SNOMEDCT_2010_1_31:83521008
database_cross_reference: UMLS_CUI:C0007192
has_exact_synonym: Alcohol-induced heart muscle disease
has_exact_synonym: Alcoholic cardiomyopathy
has_exact_synonym: Dilated cardiomyopathy secondary to alcohol (disorder)
has_obo_namespace: disease_ontology
id: DOID:12935

carotid stenosis
type: Class
subclass of: arterial occlusive disease
subclass of: carotid artery disease
imported from: doid.owl
database_cross_reference: MSH:D016893
database_cross_reference: SNOMEDCT_2010_1_31:195181000
database_cross_reference: SNOMEDCT_2010_1_31:64586002
database_cross_reference: UMLS_CUI:C0007282
has_exact_synonym: Carotid artery stenosis (disorder)
has_exact_synonym: Stenosis, carotid artery
has_obo_namespace: disease_ontology
id: DOID:13001

vertebrobasilar insufficiency
type: Class
subclass of: transient cerebral ischemia
imported from: doid.owl
database_cross_reference: ICD9CM:435.3
database_cross_reference: MSH:D014715
database_cross_reference: SNOMEDCT_2010_1_31:155404005
database_cross_reference: SNOMEDCT_2010_1_31:195196001
database_cross_reference: SNOMEDCT_2010_1_31:195199008
database_cross_reference: SNOMEDCT_2010_1_31:266314007
database_cross_reference: SNOMEDCT_2010_1_31:394517009
database_cross_reference: SNOMEDCT_2010_1_31:64009001
database_cross_reference: UMLS_CUI:C0042568
has_exact_synonym: Vertebro-basilar insufficiency
has_exact_synonym: Vertebrobasilar arterial insufficiency
has_exact_synonym: Vertebrobasilar artery syndrome
has_exact_synonym: Vertebrobasilar artery syndrome (disorder)
has_exact_synonym: Vertebrobasilar insufficiency
has_obo_namespace: disease_ontology
id: DOID:13003

persistent fetal circulation syndrome
type: Class
subclass of: pulmonary hypertension
imported from: doid.owl
database_cross_reference: ICD9CM:747.83
database_cross_reference: MSH:D010547
database_cross_reference: NCI:C85006
database_cross_reference: OMIM:265380
database_cross_reference: SNOMEDCT_2010_1_31:204507004
database_cross_reference: SNOMEDCT_2010_1_31:206597007
database_cross_reference: SNOMEDCT_2010_1_31:233815004
database_cross_reference: SNOMEDCT_2010_1_31:35604006
database_cross_reference: UMLS_CUI:C0031190
has_exact_synonym: Fetal circulation
has_exact_synonym: Persistent fetal circulation
has_exact_synonym: Persistent fetal circulation (disorder)
has_exact_synonym: Persistent fetal circulation syndrome (disorder)
has_exact_synonym: Persistent pulmonary hypertension of the newborn (disorder)
has_exact_synonym: congenital alveolar capillary dysplasia with misalignment of pulmonary veins
has_exact_synonym: persistent pulmonary hypertension of the newborn
has_obo_namespace: disease_ontology
id: DOID:13042
comment: OMIM mapping confirmed by DO. [SN].

intracranial arterial disease
type: Class
subclass of: cerebrovascular disease
imported from: doid.owl
database_cross_reference: MSH:D020765
database_cross_reference: UMLS_CUI:C0752138
has_obo_namespace: disease_ontology
id: DOID:13089

branch retinal artery occlusion
type: Class
subclass of: retinal artery occlusion
imported from: doid.owl
database_cross_reference: ICD9CM:362.32
database_cross_reference: MSH:D015356
database_cross_reference: NCI:C34436
database_cross_reference: SNOMEDCT_2010_1_31:50821009
database_cross_reference: UMLS_CUI:C0006123
has_exact_synonym: Arterial retinal branch occlusion (disorder)
has_exact_synonym: Retinal Arterial Branch Occlusion
has_exact_synonym: Retinal arterial branch occlusion
has_obo_namespace: disease_ontology
id: DOID:13094

vertebral artery insufficiency
type: Class
subclass of: transient cerebral ischemia
imported from: doid.owl
database_cross_reference: MSH:D014715
database_cross_reference: SNOMEDCT_2010_1_31:195198000
database_cross_reference: SNOMEDCT_2010_1_31:34781003
database_cross_reference: UMLS_CUI:C0042560
has_exact_synonym: Vertebral artery syndrome
has_exact_synonym: Vertebral artery syndrome (disorder)
has_obo_namespace: disease_ontology
id: DOID:13095

Sneddon syndrome
type: Class
subclass of: cerebrovascular disease
subclass of: vascular skin disease
imported from: doid.owl
database_cross_reference: MSH:D018860
database_cross_reference: OMIM:182410
database_cross_reference: SNOMEDCT_2010_1_31:238776001
database_cross_reference: UMLS_CUI:C0282492
has_exact_synonym: Idiopathic livedo reticularis with systemic involvement (disorder)
has_obo_namespace: disease_ontology
id: DOID:13096

intracranial arteriosclerosis
type: Class
subclass of: arteriosclerosis
subclass of: cerebral arterial disease
imported from: doid.owl
database_cross_reference: MSH:D002537
database_cross_reference: UMLS_CUI:C0007771
has_obo_namespace: disease_ontology
id: DOID:13097

central retinal artery occlusion
type: Class
subclass of: retinal artery occlusion
imported from: doid.owl
database_cross_reference: ICD9CM:362.31
database_cross_reference: MSH:D015356
database_cross_reference: NCI:C34456
database_cross_reference: SNOMEDCT_2010_1_31:38742007
database_cross_reference: UMLS_CUI:C0007688
has_exact_synonym: central retinal artery occlusion
has_exact_synonym: central retinal artery occlusion (disorder)
has_obo_namespace: disease_ontology
id: DOID:13098

Moyamoya disease
type: Class
subclass of: cerebral arterial disease
imported from: doid.owl
database_cross_reference: ICD9CM:437.5
database_cross_reference: MSH:D009072
database_cross_reference: NCI:C84895
database_cross_reference: OMIM:252350
database_cross_reference: SNOMEDCT_2010_1_31:69116000
database_cross_reference: SNOMEDCT_2010_1_31:89142007
database_cross_reference: UMLS_CUI:C0026654
has_exact_synonym: Moyamoya disease
has_exact_synonym: Moyamoya disease (disorder)
has_exact_synonym: progressive intracranial arterial occlusion (disorder)
has_obo_namespace: disease_ontology
id: DOID:13099
comment: OMIM mapping confirmed by DO. [SN].

intracranial vasospasm
type: Class
subclass of: cerebrovascular disease
imported from: doid.owl
database_cross_reference: MSH:D020301
database_cross_reference: UMLS_CUI:C0751895
has_obo_namespace: disease_ontology
id: DOID:13100

severe pre-eclampsia
type: Class
subclass of: pre-eclampsia
imported from: doid.owl
has_alternative_id: DOID:13130
has_alternative_id: DOID:13131
has_alternative_id: DOID:13132
database_cross_reference: ICD9CM:642.50
database_cross_reference: UMLS_CUI:C0156669
has_exact_synonym: Severe pre-eclampsia, with delivery
has_exact_synonym: antepartum severe pre-eclampsia
has_exact_synonym: postpartum severe pre-eclampsia
has_obo_namespace: disease_ontology
id: DOID:13129

HELLP syndrome
type: Class
subclass of: severe pre-eclampsia
imported from: doid.owl
database_cross_reference: MSH:D017359
database_cross_reference: NCI:C84750
database_cross_reference: SNOMEDCT_2010_1_31:199010001
database_cross_reference: SNOMEDCT_2010_1_31:95605009
database_cross_reference: UMLS_CUI:C0162739
has_exact_synonym: HELLP syndrome (disorder)
has_exact_synonym: syndrome of haemolysis, elevated liver enzymes and low platelet
has_obo_namespace: disease_ontology
id: DOID:13133

benign secondary hypertension
type: Class
subclass of: secondary hypertension
imported from: doid.owl
database_cross_reference: ICD9CM:405.1
database_cross_reference: NCI:C3658
database_cross_reference: SNOMEDCT_2010_1_31:194785008
database_cross_reference: SNOMEDCT_2010_1_31:194787000
database_cross_reference: SNOMEDCT_2010_1_31:44111003
database_cross_reference: UMLS_CUI:C0155620
has_obo_namespace: disease_ontology
id: DOID:13143

benign renovascular hypertension
type: Class
subclass of: benign secondary hypertension
imported from: doid.owl
database_cross_reference: ICD9CM:405.11
database_cross_reference: UMLS_CUI:C0155621
has_obo_namespace: disease_ontology
id: DOID:13145

right bundle branch block (disease)
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: right bundle branch block (process)
subclass of: Restriction
  on property: has material basis at all times
  some values from: impaired right branch of atrioventricular bundle
imported from: doid.owl
database_cross_reference: ICD9CM:426.51
database_cross_reference: SNOMEDCT_2010_1_31:46319007
database_cross_reference: UMLS_CUI:C0155704
has_exact_synonym: Right bundle branch block with left posterior fascicular block (disorder)
has_obo_namespace: disease_ontology
id: DOID:13209

Behcet's disease
type: Class
subclass of: vascular disease - unclassified by CVDO
definition: An autoimmune disease of cardiovascular system that causes chronic inflammation in blood vessels throughout the body leading to ulcerations on the mouth and sometimes the genitals, notorious for causing hypopyon uveitis.
imported from: doid.owl
database_cross_reference: ICD9CM:136.1
database_cross_reference: MSH:D001528
database_cross_reference: NCI:C34416
database_cross_reference: OMIM:109650
database_cross_reference: SNOMEDCT_2010_1_31:154424000
database_cross_reference: SNOMEDCT_2010_1_31:310701003
database_cross_reference: SNOMEDCT_2010_1_31:41225007
database_cross_reference: UMLS_CUI:C0004943
has_exact_synonym: Adamantiades-Behcet disease
has_exact_synonym: Behcet syndrome
has_exact_synonym: Behet's syndrome (disorder)
has_exact_synonym: triple symptom complex
has_obo_namespace: disease_ontology
has_related_synonym: Behcet's syndrome
id: DOID:13241
comment: OMIM mapping confirmed by DO. [SN].

temporal arteritis
type: Class
subclass of: central nervous system vasculitis
imported from: doid.owl
database_cross_reference: ICD9CM:446.5
database_cross_reference: MSH:D013700
database_cross_reference: NCI:C35065
database_cross_reference: OMIM:187360
database_cross_reference: SNOMEDCT_2010_1_31:155442004
database_cross_reference: SNOMEDCT_2010_1_31:195354005
database_cross_reference: SNOMEDCT_2010_1_31:195355006
database_cross_reference: SNOMEDCT_2010_1_31:195356007
database_cross_reference: SNOMEDCT_2010_1_31:195357003
database_cross_reference: SNOMEDCT_2010_1_31:400130008
database_cross_reference: SNOMEDCT_2010_1_31:414341000
database_cross_reference: SNOMEDCT_2010_1_31:87511001
database_cross_reference: UMLS_CUI:C0039483
has_exact_synonym: Giant cell Arteritis
has_exact_synonym: Giant cell arteritis
has_exact_synonym: Giant cell arteritis (disorder)
has_exact_synonym: Giant cell arteritis NOS (disorder)
has_exact_synonym: Horton's disease
has_exact_synonym: Temporal arteritis (disorder)
has_exact_synonym: giant cell arteritis
has_obo_namespace: disease_ontology
id: DOID:13375
comment: OMIM mapping confirmed by DO. [LS].

Kawasaki disease
type: Class
subclass of: polyarteritis nodosa
imported from: doid.owl
database_cross_reference: ICD9CM:446.1
database_cross_reference: MSH:D009080
database_cross_reference: NCI:C34825
database_cross_reference: OMIM:611775
database_cross_reference: SNOMEDCT_2010_1_31:155444003
database_cross_reference: SNOMEDCT_2010_1_31:195348009
database_cross_reference: SNOMEDCT_2010_1_31:195349001
database_cross_reference: SNOMEDCT_2010_1_31:75053002
database_cross_reference: UMLS_CUI:C0026691
has_exact_synonym: Kawasaki disease
has_exact_synonym: Kawasaki's disease
has_exact_synonym: MLNS
has_exact_synonym: acute febrile MCLS
has_exact_synonym: acute febrile mucocutaneous lymph node syndrome (disorder)
has_exact_synonym: acute febrile mucocutaneous lymph node syndrome NOS (disorder)
has_exact_synonym: acute febrile mucocutaneous lymph node syndrome [MCLS]
has_exact_synonym: mucocutaneous lymph node syndrome
has_obo_namespace: disease_ontology
id: DOID:13378
comment: OMIM mapping confirmed by DO. [SN].

basilar artery occlusion
type: Class
subclass of: occlusion precerebral artery
imported from: doid.owl
database_cross_reference: ICD9CM:433.0
database_cross_reference: SNOMEDCT_2010_1_31:155396001
database_cross_reference: SNOMEDCT_2010_1_31:195180004
database_cross_reference: SNOMEDCT_2010_1_31:78658006
database_cross_reference: UMLS_CUI:C0265098
has_obo_namespace: disease_ontology
id: DOID:13446

eclampsia
type: Class
subclass of: pre-eclampsia
imported from: doid.owl
has_alternative_id: DOID:13592
database_cross_reference: MSH:D004461
database_cross_reference: NCI:C87167
database_cross_reference: SNOMEDCT_2010_1_31:156111007
database_cross_reference: SNOMEDCT_2010_1_31:15938005
database_cross_reference: SNOMEDCT_2010_1_31:198988006
database_cross_reference: SNOMEDCT_2010_1_31:198989003
database_cross_reference: SNOMEDCT_2010_1_31:198996001
database_cross_reference: UMLS_CUI:C0013537
has_exact_synonym: Eclampsia (disorder)
has_exact_synonym: Eclampsia NOS (disorder)
has_exact_synonym: Eclampsia in puerperium (disorder)
has_exact_synonym: Eclampsia unspecified (disorder)
has_exact_synonym: Eclampsia, postpartum
has_exact_synonym: Postpartum eclampsia
has_exact_synonym: eclampsia
has_obo_namespace: disease_ontology
id: DOID:13593

malignant renovascular hypertension
type: Class
subclass of: malignant secondary hypertension
imported from: doid.owl
database_cross_reference: UMLS_CUI:C0155618
has_obo_namespace: disease_ontology
id: DOID:13730

malignant secondary hypertension
type: Class
subclass of: malignant hypertension
subclass of: secondary hypertension
imported from: doid.owl
database_cross_reference: ICD9CM:405.0
database_cross_reference: SNOMEDCT_2010_1_31:194784007
database_cross_reference: SNOMEDCT_2010_1_31:49863005
database_cross_reference: SNOMEDCT_2010_1_31:89242004
database_cross_reference: UMLS_CUI:C0155617
has_obo_namespace: disease_ontology
id: DOID:13731

infarct of liver
type: Class
subclass of: hepatic vascular disease
imported from: doid.owl
database_cross_reference: ICD9CM:573.4
database_cross_reference: SNOMEDCT_2010_1_31:17890003
database_cross_reference: UMLS_CUI:C0151731
has_exact_synonym: hepatic infarction
has_exact_synonym: hepatic infarction (disorder)
has_obo_namespace: disease_ontology
id: DOID:13738

nutmeg liver
type: Class
subclass of: hepatic vascular disease
imported from: doid.owl
database_cross_reference: ICD9CM:573.0
database_cross_reference: SNOMEDCT_2010_1_31:34736002
database_cross_reference: UMLS_CUI:C0156195
has_exact_synonym: chronic passive congestion of liver
has_exact_synonym: chronic passive congestion of liver (disorder)
has_obo_namespace: disease_ontology
id: DOID:13739

rheumatic tricuspid valve disease
type: Class
subclass of: tricuspid valve disease
imported from: doid.owl
database_cross_reference: ICD9CM:397.0
database_cross_reference: SNOMEDCT_2010_1_31:155289000
database_cross_reference: SNOMEDCT_2010_1_31:194745002
database_cross_reference: SNOMEDCT_2010_1_31:266282000
database_cross_reference: SNOMEDCT_2010_1_31:49699002
database_cross_reference: UMLS_CUI:C0264776
has_exact_synonym: RH. tricuspid valve disease
has_exact_synonym: Rheumatic disease of tricuspid valve (disorder)
has_exact_synonym: Rheumatic tricuspid valve disease NOS (disorder)
has_exact_synonym: Tricuspid disease
has_exact_synonym: disease of tricuspid valve
has_obo_namespace: disease_ontology
id: DOID:13834

sick sinus syndrome
type: Class
subclass of: heart conduction disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Class
      union of: Restriction
        on property: has occurrent part
        some values from: sinoatrial arrest (process)
      union of: Restriction
        on property: has occurrent part
        some values from: sinus bradycardia (process)
subclass of: Restriction
  on property: has material basis at all times
  some values from: impaired sinus node
CVDO definition: A heart conduction disease characterized by inappropriate sinus rates (e.g. sinus bradycardia or sinus pause).
imported from: doid.owl
database_cross_reference: MSH:D012804
database_cross_reference: NCI:C62244
database_cross_reference: SNOMEDCT_2010_1_31:155373001
database_cross_reference: SNOMEDCT_2010_1_31:266307005
database_cross_reference: SNOMEDCT_2010_1_31:36083008
database_cross_reference: UMLS_CUI:C0037052
has_obo_namespace: disease_ontology
id: DOID:13884

thoracic aortic aneurysm
type: Class
subclass of: aortic aneurysm
imported from: doid.owl
database_cross_reference: ICD9CM:441.2
database_cross_reference: MSH:D017545
database_cross_reference: NCI:C27001
database_cross_reference: OMIM:132900
database_cross_reference: OMIM:611788
database_cross_reference: SNOMEDCT_2010_1_31:155421001
database_cross_reference: SNOMEDCT_2010_1_31:195259003
database_cross_reference: SNOMEDCT_2010_1_31:433068007
database_cross_reference: SNOMEDCT_2010_1_31:74883004
database_cross_reference: UMLS_CUI:C0162872
has_exact_synonym: Thoracic Aortic Aneurysm
has_exact_synonym: Thoracic aortic aneurysm
has_exact_synonym: Thoracic aortic aneurysm without mention of rupture
has_exact_synonym: Thoracic aortic aneurysm without mention of rupture (disorder)
has_exact_synonym: Thoracic aortic aneurysm without rupture
has_obo_namespace: disease_ontology
id: DOID:14004
comment: OMIM mapping confirmed by DO. [SN].
label: thoracic aortic aneurysm disease

splenic artery aneurysm
type: Class
subclass of: aneurysm (disease)
imported from: doid.owl
database_cross_reference: ICD9CM:442.83
database_cross_reference: SNOMEDCT_2010_1_31:70405009
database_cross_reference: UMLS_CUI:C0155747
has_obo_namespace: disease_ontology
id: DOID:14006
label: splenic artery aneurysm disease

aorta atresia
type: Class
subclass of: aortic disease
imported from: doid.owl
database_cross_reference: ICD9CM:747.22
database_cross_reference: SNOMEDCT_2010_1_31:204431007
database_cross_reference: SNOMEDCT_2010_1_31:204438001
database_cross_reference: UMLS_CUI:C0345010
has_exact_synonym: Atresia and stenosis of aorta (disorder)
has_exact_synonym: Atresia or stenosis of aorta NOS (disorder)
has_exact_synonym: Congenital atresia and stenosis of aorta
has_obo_namespace: disease_ontology
id: DOID:14037

renal artery atheroma
type: Class
subclass of: atherosclerosis
subclass of: renal vascular disease
imported from: doid.owl
database_cross_reference: ICD9CM:440.1
database_cross_reference: SNOMEDCT_2010_1_31:155416004
database_cross_reference: SNOMEDCT_2010_1_31:45281005
database_cross_reference: UMLS_CUI:C0155734
has_exact_synonym: Atherosclerosis of renal artery
has_exact_synonym: Atherosclerosis of renal artery (disorder)
has_exact_synonym: renal atherosclerosis
has_obo_namespace: disease_ontology
id: DOID:14092

blue toe syndrome
type: Class
subclass of: vascular disease - unclassified by CVDO
imported from: doid.owl
database_cross_reference: MSH:D018438
database_cross_reference: UMLS_CUI:C0242645
has_obo_namespace: disease_ontology
id: DOID:14121

rheumatic congestive heart failure
type: Class
subclass of: congestive heart failure
CVDO definition: A congestive heart failure caused by a rheumatic fever.
imported from: doid.owl
database_cross_reference: ICD9CM:398.91
database_cross_reference: SNOMEDCT_2010_1_31:82523003
database_cross_reference: UMLS_CUI:C0155582
has_exact_synonym: Congestive rheumatic heart failure (disorder)
has_exact_synonym: Rheumatic heart failure
has_exact_synonym: Rheumatic heart failure (congestive)
has_obo_namespace: disease_ontology
id: DOID:14172

pulmonary valve insufficiency
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: pulmonary valve improper close during right ventricular diastole
  intersection of: Restriction
    on property: has material basis at all times
    some values from: pulmonary valve disorder
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: retrograd blood flow through pulmonary valve during right ventricular diastole
CVDO definition: A disease in which an abnormal structure in a pulmonary valve prevents it to close propertly during diastole, occasioning a retrograd blood flow through the valve.
definition: A pulmonary valve disease that occurs when the pulmonary valve is not strong enough to prevent backflow into the right ventricle. If it is secondary to pulmonary hypertension it is referred to as a Graham Steell murmur.
imported from: doid.owl
has_alternative_id: DOID:11210
database_cross_reference: ICD9CM:518.5
database_cross_reference: UMLS_CUI:C0034076
has_exact_synonym: Pulmonic insufficiency NOS
has_exact_synonym: Pulmonic valve regurgitation (disorder)
has_exact_synonym: pulmonary incompetence
has_exact_synonym: pulmonary incompetence, non-rheumatic (disorder)
has_exact_synonym: pulmonary insufficiency following trauma and surgery
has_exact_synonym: pulmonary regurg.
has_exact_synonym: pulmonary regurgitation
has_obo_namespace: disease_ontology
id: DOID:14265

thrombophlebitis migrans
type: Class
subclass of: thrombophlebitis
imported from: doid.owl
database_cross_reference: ICD9CM:453.1
database_cross_reference: SNOMEDCT_2010_1_31:155456002
database_cross_reference: SNOMEDCT_2010_1_31:155491005
database_cross_reference: SNOMEDCT_2010_1_31:31268005
database_cross_reference: UMLS_CUI:C0152250
has_exact_synonym: Thrombophlebitis migrans (disorder)
has_obo_namespace: disease_ontology
id: DOID:14392

capillary leak syndrome
type: Class
subclass of: capillary disease
subclass of: vascular skin disease
imported from: doid.owl
database_cross_reference: MSH:D019559
database_cross_reference: NCI:C62578
database_cross_reference: SNOMEDCT_2010_1_31:87730004
database_cross_reference: UMLS_CUI:C0343084
has_exact_synonym: Capillary leak syndrome (disorder)
has_obo_namespace: disease_ontology
id: DOID:14400

cholinergic urticaria
type: Class
subclass of: dermatographia
imported from: doid.owl
database_cross_reference: ICD9CM:708.5
database_cross_reference: SNOMEDCT_2010_1_31:73098005
database_cross_reference: UMLS_CUI:C0152230
has_exact_synonym: Cholinergic urticaria (disorder)
has_obo_namespace: disease_ontology
id: DOID:14443

partial arterial retinal occlusion
type: Class
subclass of: retinal artery occlusion
imported from: doid.owl
database_cross_reference: ICD9CM:362.33
database_cross_reference: NCI:C35192
database_cross_reference: SNOMEDCT_2010_1_31:193376004
database_cross_reference: SNOMEDCT_2010_1_31:776009
database_cross_reference: UMLS_CUI:C0154839
has_exact_synonym: Partial Retinal Arterial Occlusion
has_exact_synonym: Partial arterial retinal occlusion (disorder)
has_exact_synonym: Partial retinal arterial occlusion
has_exact_synonym: Retinal partial arterial occlusion NOS (disorder)
has_obo_namespace: disease_ontology
id: DOID:14522

primary pulmonary hypertension
type: Class
subclass of: pulmonary hypertension
imported from: doid.owl
database_cross_reference: ICD9CM:416.0
database_cross_reference: MSH:C536282
database_cross_reference: OMIM:178600
database_cross_reference: OMIM:265400
database_cross_reference: SNOMEDCT_2010_1_31:155328008
database_cross_reference: SNOMEDCT_2010_1_31:26174007
database_cross_reference: SNOMEDCT_2010_1_31:266293003
database_cross_reference: UMLS_CUI:C0152171
has_exact_synonym: primary pulmonary hypertension
has_exact_synonym: primary pulmonary hypertension (disorder)
has_exact_synonym: pulmonary hypertension (& [primary])
has_exact_synonym: pulmonary hypertension, idiopathic
has_obo_namespace: disease_ontology
id: DOID:14557
comment: OMIM mapping confirmed by DO. [SN].

atheroembolism of kidney
type: Class
subclass of: cholesterol embolism
imported from: doid.owl
database_cross_reference: UMLS_CUI:C1135215
has_obo_namespace: disease_ontology
id: DOID:1460

cholesterol embolism
type: Class
subclass of: embolism
CVDO definition: An embolism due to an embolus made of cholesterol.
imported from: doid.owl
database_cross_reference: ICD9CM:445
database_cross_reference: MSH:D017700
database_cross_reference: SNOMEDCT_2010_1_31:10690002
database_cross_reference: UMLS_CUI:C0149649
has_obo_namespace: disease_ontology
id: DOID:1461

hereditary angioedema
type: Class
subclass of: angioedema
imported from: doid.owl
database_cross_reference: MSH:D054179
database_cross_reference: NCI:C84758
database_cross_reference: OMIM:106100
database_cross_reference: OMIM:610618
database_cross_reference: SNOMEDCT_2010_1_31:82966003
database_cross_reference: UMLS_CUI:C0019243
has_exact_synonym: HANE
has_exact_synonym: Hereditary angioedema
has_exact_synonym: Hereditary angioneurotic edema (disorder)
has_obo_namespace: disease_ontology
id: DOID:14735
comment: OMIM mapping confirmed by DO. [SN].

vibratory urticaria
type: Class
subclass of: dermatographia
imported from: doid.owl
database_cross_reference: ICD9CM:708.4
database_cross_reference: SNOMEDCT_2010_1_31:51247001
database_cross_reference: UMLS_CUI:C0157743
has_exact_synonym: Vibratory urticaria (disorder)
has_obo_namespace: disease_ontology
id: DOID:1554

urticaria
type: Class
subclass of: vascular skin disease
imported from: doid.owl
database_cross_reference: ICD9CM:708.8
database_cross_reference: MSH:D014581
database_cross_reference: SNOMEDCT_2010_1_31:201267004
database_cross_reference: SNOMEDCT_2010_1_31:201271001
database_cross_reference: SNOMEDCT_2010_1_31:267817001
database_cross_reference: UMLS_CUI:C0029839
has_obo_namespace: disease_ontology
id: DOID:1555

angioedema
type: Class
subclass of: urticaria
imported from: doid.owl
database_cross_reference: MSH:D000799
database_cross_reference: SNOMEDCT_2010_1_31:157756002
database_cross_reference: SNOMEDCT_2010_1_31:269433002
database_cross_reference: SNOMEDCT_2010_1_31:400075008
database_cross_reference: SNOMEDCT_2010_1_31:41291007
database_cross_reference: SNOMEDCT_2010_1_31:82966003
database_cross_reference: UMLS_CUI:C0002994
has_exact_synonym: Angioedema (disorder)
has_exact_synonym: Angioneurotic oedema
has_exact_synonym: Giant urticaria
has_exact_synonym: Giant urticaria (disorder)
has_exact_synonym: QUINCKE'S EDEMA
has_exact_synonym: Quincke's edema
has_exact_synonym: angioedema
has_exact_synonym: angioneurotic edema
has_exact_synonym: giant urticaria
has_obo_namespace: disease_ontology
id: DOID:1558

renovascular hypertension
type: Class
subclass of: renal hypertension
imported from: doid.owl
database_cross_reference: MSH:D006978
database_cross_reference: NCI:C85044
database_cross_reference: SNOMEDCT_2010_1_31:123799005
database_cross_reference: SNOMEDCT_2010_1_31:194790006
database_cross_reference: UMLS_CUI:C0020545
has_exact_synonym: Renovascular hypertension (disorder)
has_obo_namespace: disease_ontology
id: DOID:1591

breast angiomatosis
type: Class
subclass of: vascular tissue disease
imported from: doid.owl
database_cross_reference: NCI:C40381
database_cross_reference: UMLS_CUI:C1511284
has_obo_namespace: disease_ontology
id: DOID:1637

aortic valve stenosis
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: aortic valve improper opening during left ventricular systole
  intersection of: Restriction
    on property: has material basis at all times
    some values from: aortic valve disorder
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: disturbed anterograd blood flow through aortic valve during left ventricular systole
CVDO definition: A disease in which some disorder of the aortic valve leads prevents it from opening properly during left ventricular systole, occasioning disturbance in the anterograd blood flow through the valve.
definition: Aortic valve stenosis is a aortic valve disease caused by the incomplete opening of the aortic valve. The aortic valve controls the direction of blood flow from the left ventricle to the aorta. When in good working order, the aortic valve does not impede the flow of blood between these two spaces. Under some circumstances, the aortic valve becomes narrower than normal, impeding the flow of blood. This is known as aortic valve stenosis, or aortic stenosis, often abbreviated AS.
imported from: doid.owl
database_cross_reference: MSH:D001024
database_cross_reference: NCI:C50462
database_cross_reference: SNOMEDCT_2010_1_31:390722003
database_cross_reference: SNOMEDCT_2010_1_31:60573004
database_cross_reference: UMLS_CUI:C0003507
has_exact_synonym: AS
has_exact_synonym: Aortic stenosis
has_exact_synonym: Aortic valve stenosis (disorder)
has_exact_synonym: aortic valve stenosis
has_obo_namespace: disease_ontology
id: DOID:1712

retinal vascular occlusion
type: Class
subclass of: retinal vascular disease
imported from: doid.owl
database_cross_reference: ICD9CM:362.3
database_cross_reference: ICD9CM:362.30
database_cross_reference: NCI:C34980
database_cross_reference: SNOMEDCT_2010_1_31:155111000
database_cross_reference: SNOMEDCT_2010_1_31:193373007
database_cross_reference: SNOMEDCT_2010_1_31:193380009
database_cross_reference: SNOMEDCT_2010_1_31:267717005
database_cross_reference: SNOMEDCT_2010_1_31:73757007
database_cross_reference: UMLS_CUI:C0035326
has_exact_synonym: Retinal vasc. occlusion
has_exact_synonym: Retinal vascular Occlusion
has_exact_synonym: Retinal vascular occlusion (disorder)
has_exact_synonym: Retinal vascular occlusion NOS (disorder)
has_exact_synonym: Retinal vascular occlusion, unspecified
has_exact_synonym: Unspecified retinal vascular occlusion (disorder)
has_obo_namespace: disease_ontology
id: DOID:1729

mitral valve stenosis
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: mitral valve narrowed opening during left ventricular diastole
  intersection of: Restriction
    on property: has material basis at all times
    some values from: mitral valve disorder
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: disturbed anterograd blood flow through mitral valve during left ventricular diastole
CVDO definition: A disease in which some disorder of a mitral valve prevents it from opening properly during left ventricular diastole, occasioning disturbance in the anterograd blood flow through the valve.
definition: Mitral valve stenosis is a rheumatic disease of mitral valve characterized by the narrowing of the orifice of the mitral valve of the heart. Most cases of mitral stenosis are due to disease in the heart secondary to rheumatic fever and the consequent rheumatic heart disease. Less common causes of mitral stenosis are calcification of the mitral valve leaflets, and as a form of congenital heart disease. However, there are primary causes of mitral stenosis that emanate from a cleft mitral valve. Other causes include Bacterial endocarditis where the vegetations may favor increase risk of stenosis.
imported from: doid.owl
database_cross_reference: MSH:D008946
database_cross_reference: NCI:C50654
database_cross_reference: SNOMEDCT_2010_1_31:155277002
database_cross_reference: SNOMEDCT_2010_1_31:194725005
database_cross_reference: SNOMEDCT_2010_1_31:79619009
database_cross_reference: UMLS_CUI:C0026269
has_exact_synonym: Mitral stenosis
has_exact_synonym: Mitral stenosis NOS
has_exact_synonym: Mitral valve stenosis (disorder)
has_exact_synonym: mitral valve stenosis
has_obo_namespace: disease_ontology
id: DOID:1754

vascular disease
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Class
    union of: Restriction
      on property: realized in
      some values from: Class
        intersection of: disease course
        intersection of: Restriction
    union of: Restriction
      on property: has material basis at all times
      some values from: vascular disorder
CVDO definition: A disease affecting a blood vessel.
CVDO editor note: Reorganization of the vascular diseases, and writing of Aristotelian definitions, is still ongoing.
definition: A cardiovascular system disease that primarily affects the blood vessels.
imported from: doid.owl
has_alternative_id: DOID:2869
has_alternative_id: DOID:45
database_cross_reference: MSH:D014652
database_cross_reference: NCI:C35117
database_cross_reference: SNOMEDCT_2010_1_31:27550009
database_cross_reference: UMLS_CUI:C0042373
database_cross_reference: UMLS_CUI:C0264951
has_exact_synonym: arteriopathy
has_exact_synonym: internal elastic lamina
has_obo_namespace: disease_ontology
has_related_synonym: Arterial disease
id: DOID:178

pericarditis
type: Class
subclass of: disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: inflammation process in a pericardium
CVDO definition: A disease characterized by an inflammation of the pericardium.
definition: A heart disease that is characterized by an inflammation of the pericardium and has_symptom chest pain.
imported from: doid.owl
database_cross_reference: MSH:D010493
database_cross_reference: NCI:C34915
database_cross_reference: SNOMEDCT_2010_1_31:3238004
database_cross_reference: UMLS_CUI:C0031046
has_obo_namespace: disease_ontology
id: DOID:1787

chronic rheumatic pericarditis
type: Class
subclass of: pericarditis
subclass of: Class
  intersection of: pericarditis
  intersection of: Restriction
    on property: realized in
    some values from: chronic disease course
CVDO definition: A chronic pericarditis due to rheumatic fever.
imported from: doid.owl
database_cross_reference: ICD9CM:393
database_cross_reference: SNOMEDCT_2010_1_31:155287003
database_cross_reference: SNOMEDCT_2010_1_31:194719006
database_cross_reference: SNOMEDCT_2010_1_31:194723003
database_cross_reference: SNOMEDCT_2010_1_31:78069008
database_cross_reference: UMLS_CUI:C0155561
has_exact_synonym: chronic rheumatic pericarditis (disorder)
has_exact_synonym: chronic rheumatic pericarditis NOS (disorder)
has_obo_namespace: disease_ontology
id: DOID:1869

supravalvular aortic stenosis
type: Class
subclass of: congenital disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: disturbed anterograd blood flow through aortic valve during left ventricular systole
    intersection of: Restriction
      on property: has occurrent part
      some values from: aortic valve improper opening during left ventricular systole
    intersection of: Restriction
      on property: has occurrent part
      some values from: aorta pathological process
CVDO definition: A congenital disease involving the narrowing (stenosis) of aorta, hindering the opening of the aortic valve.
CVDO editor note: Supravalvular aortic stenosis is not classified as an aortic valve stenosis: although the narrowing of the section of the aorta at the exit of the aortic valve implies some improper opening of the aortic valve, the aortic valve is (in general) healthy (there is no disorder nor pathological process inside it). However, this improper opening of the aortic valve is a pathological process that happens inside the heart; therefore, supravalvular aortic stenosis is classified as a heart disease.
imported from: doid.owl
database_cross_reference: MSH:D021921
database_cross_reference: NCI:C85176
database_cross_reference: OMIM:185500
database_cross_reference: OMIM:194050
database_cross_reference: SNOMEDCT_2010_1_31:204436002
database_cross_reference: SNOMEDCT_2010_1_31:268185002
database_cross_reference: UMLS_CUI:C0003499
has_exact_synonym: Supra-valvular aortic stenosis
has_exact_synonym: Supravalvar aortic stenosis (disorder)
has_obo_namespace: disease_ontology
id: DOID:1929

atherosclerosis
type: Class
subclass of: arteriosclerosis
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: atheromous plaque formation in artery
imported from: doid.owl
database_cross_reference: ICD9CM:440
database_cross_reference: MSH:D050197
database_cross_reference: NCI:C35768
database_cross_reference: SNOMEDCT_2010_1_31:155382007
database_cross_reference: SNOMEDCT_2010_1_31:155414001
database_cross_reference: SNOMEDCT_2010_1_31:194848007
database_cross_reference: SNOMEDCT_2010_1_31:195251000
database_cross_reference: SNOMEDCT_2010_1_31:266318005
database_cross_reference: SNOMEDCT_2010_1_31:38716007
database_cross_reference: UMLS_CUI:C0004153
has_obo_namespace: disease_ontology
id: DOID:1936

basilar artery insufficiency
type: Class
subclass of: transient cerebral ischemia
imported from: doid.owl
database_cross_reference: ICD9CM:435.0
database_cross_reference: MSH:D014715
database_cross_reference: NCI:C34413
database_cross_reference: SNOMEDCT_2010_1_31:195197005
database_cross_reference: SNOMEDCT_2010_1_31:64009001
database_cross_reference: UMLS_CUI:C0004812
has_exact_synonym: Basilar artery syndrome
has_exact_synonym: Basilar artery syndrome (disorder)
has_obo_namespace: disease_ontology
id: DOID:223

transient cerebral ischemia
type: Class
equivalent class: Class
  intersection of: brain ischemia
  intersection of: Restriction
    on property: part of occurrent
    some values from: transient disease course
subclass of: brain ischemia
CVDO definition: A brain ischemia that is part of a transient disease course.
imported from: doid.owl
has_alternative_id: DOID:2315
database_cross_reference: MSH:D002546
database_cross_reference: NCI:C50781
database_cross_reference: SNOMEDCT_2010_1_31:155404005
database_cross_reference: SNOMEDCT_2010_1_31:195196001
database_cross_reference: SNOMEDCT_2010_1_31:195207009
database_cross_reference: SNOMEDCT_2010_1_31:266257000
database_cross_reference: SNOMEDCT_2010_1_31:266314007
database_cross_reference: SNOMEDCT_2010_1_31:313242003
database_cross_reference: SNOMEDCT_2010_1_31:38609002
database_cross_reference: UMLS_CUI:C0007787
database_cross_reference: UMLS_CUI:C0155728
has_exact_synonym: TIA
has_exact_synonym: TIA - Transient ischaemic attack
has_exact_synonym: TRANSIENT ISCHEMIC ATTACK
has_exact_synonym: Transient cerebral ischaemia
has_exact_synonym: Transient cerebral ischaemia NOS
has_exact_synonym: Transient cerebral ischemia (disorder) [Ambiguous]
has_exact_synonym: Transient ischemic attacks (disorder)
has_exact_synonym: transient ischemic attack
has_obo_namespace: disease_ontology
id: DOID:224

brain ischemia
type: Class
subclass of: ischemia
CVDO definition: An ischemia of the brain.
imported from: doid.owl
database_cross_reference: MSH:D002545
database_cross_reference: SNOMEDCT_2010_1_31:11890005
database_cross_reference: SNOMEDCT_2010_1_31:193049009
database_cross_reference: SNOMEDCT_2010_1_31:389100007
database_cross_reference: UMLS_CUI:C0007786
has_exact_synonym: Ischaemic encephalopathy
has_exact_synonym: Ischemic encephalopathy (disorder)
has_obo_namespace: disease_ontology
id: DOID:2316

generalized atherosclerosis
type: Class
subclass of: atherosclerosis
imported from: doid.owl
database_cross_reference: ICD9CM:440.9
database_cross_reference: NCI:C35767
database_cross_reference: SNOMEDCT_2010_1_31:367108003
database_cross_reference: SNOMEDCT_2010_1_31:39823006
database_cross_reference: UMLS_CUI:C0017327
has_exact_synonym: Generalised atherosclerosis
has_exact_synonym: Generalized and unspecified atherosclerosis
has_exact_synonym: Generalized atherosclerosis (disorder)
has_obo_namespace: disease_ontology
id: DOID:2347

arteriosclerotic cardiovascular disease
type: Class
subclass of: arteriosclerosis
imported from: doid.owl
database_cross_reference: NCI:C34403
database_cross_reference: NCI:C35771
database_cross_reference: SNOMEDCT_2010_1_31:195121002
database_cross_reference: SNOMEDCT_2010_1_31:195251000
database_cross_reference: SNOMEDCT_2010_1_31:39468009
database_cross_reference: UMLS_CUI:C0003972
has_exact_synonym: Arteriosclerotic Cardiovascular disease
has_exact_synonym: Arteriosclerotic cardiovascular disease
has_exact_synonym: Arteriosclerotic cardiovascular disease, NOS
has_exact_synonym: Atherosclerotic Cardiovascular disease
has_exact_synonym: Atherosclerotic cardiovascular disease
has_exact_synonym: Cardiovascular arteriosclerosis unspecified (disorder)
has_obo_namespace: disease_ontology
id: DOID:2348

arteriosclerosis
type: Class
subclass of: arterial occlusive disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: artery hardening
imported from: doid.owl
database_cross_reference: MSH:D001161
database_cross_reference: NCI:C34398
database_cross_reference: SNOMEDCT_2010_1_31:107671003
database_cross_reference: SNOMEDCT_2010_1_31:155414001
database_cross_reference: SNOMEDCT_2010_1_31:155418003
database_cross_reference: SNOMEDCT_2010_1_31:195251000
database_cross_reference: SNOMEDCT_2010_1_31:195257001
database_cross_reference: SNOMEDCT_2010_1_31:266318005
database_cross_reference: SNOMEDCT_2010_1_31:28960008
database_cross_reference: SNOMEDCT_2010_1_31:72092001
database_cross_reference: UMLS_CUI:C0003850
has_exact_synonym: Arteriosclerosis (morphologic abnormality)
has_exact_synonym: Arteriosclerosis NOS
has_exact_synonym: Arteriosclerotic vascular disease (disorder)
has_exact_synonym: Arteriosclerotic vascular disease NOS
has_exact_synonym: Arteriosclerotic vascular disease NOS (disorder)
has_exact_synonym: arteriosclerosis
has_obo_namespace: disease_ontology
id: DOID:2349

postphlebitic syndrome
type: Class
subclass of: venous insufficiency
imported from: doid.owl
has_alternative_id: DOID:12820
has_alternative_id: DOID:2363
has_alternative_id: DOID:2720
database_cross_reference: ICD9CM:459.1
database_cross_reference: MSH:D011186
database_cross_reference: SNOMEDCT_2010_1_31:155460004
database_cross_reference: SNOMEDCT_2010_1_31:20427003
database_cross_reference: SNOMEDCT_2010_1_31:410013001
database_cross_reference: UMLS_CUI:C0032807
database_cross_reference: UMLS_CUI:C1135219
database_cross_reference: UMLS_CUI:C1135220
database_cross_reference: UMLS_CUI:C1135221
has_exact_synonym: Postphlebetic syndrome with inflammation
has_exact_synonym: Postphlebetic syndrome with ulcer
has_exact_synonym: Postphlebetic syndrome with ulcer and inflammation
has_obo_namespace: disease_ontology
id: DOID:2364

renal vascular disease
type: Class
subclass of: vascular disease - unclassified by CVDO
imported from: doid.owl
database_cross_reference: ICD9CM:593.81
database_cross_reference: NCI:C35338
database_cross_reference: SNOMEDCT_2010_1_31:16934004
database_cross_reference: SNOMEDCT_2010_1_31:197814004
database_cross_reference: SNOMEDCT_2010_1_31:266559003
database_cross_reference: UMLS_CUI:C0268790
has_exact_synonym: vascular disorder of kidney
has_obo_namespace: disease_ontology
id: DOID:2388

aneurysm (disease)
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: has material basis at all times
    some values from: aneurysm (disorder)
CVDO definition: A disposition that an aneurysm disorder will lead to pathological processes.
CVDO editor note: DOID label 'aneurysm disease' changed for homogeneization purpose in CVDO.
definition: A vascular disease that is characterized by a localized, blood-filled balloon-like bulge in the wall of a blood vessel.
imported from: doid.owl
database_cross_reference: ICD9CM:442.9
database_cross_reference: MSH:D000783
database_cross_reference: NCI:C26693
database_cross_reference: SNOMEDCT_2010_1_31:134342004
database_cross_reference: SNOMEDCT_2010_1_31:155425005
database_cross_reference: SNOMEDCT_2010_1_31:155428007
database_cross_reference: SNOMEDCT_2010_1_31:195292009
database_cross_reference: SNOMEDCT_2010_1_31:362727005
database_cross_reference: SNOMEDCT_2010_1_31:432119003
database_cross_reference: SNOMEDCT_2010_1_31:85659009
database_cross_reference: UMLS_CUI:C0002940
has_obo_namespace: disease_ontology
id: DOID:2403

retinal vascular disease
type: Class
subclass of: vascular disease - unclassified by CVDO
imported from: doid.owl
database_cross_reference: NCI:C35170
database_cross_reference: SNOMEDCT_2010_1_31:57534004
database_cross_reference: UMLS_CUI:C0154833
has_exact_synonym: retina circulation disorder
has_obo_namespace: disease_ontology
id: DOID:2462

gastric antral vascular ectasia
type: Class
subclass of: capillary disease
imported from: doid.owl
database_cross_reference: MSH:D020252
database_cross_reference: NCI:C84724
database_cross_reference: SNOMEDCT_2010_1_31:412795008
database_cross_reference: SNOMEDCT_2010_1_31:43935004
database_cross_reference: UMLS_CUI:C0267211
has_exact_synonym: Watermelon stomach (disorder)
has_exact_synonym: gastric antral vascular ectasia (disorder)
has_obo_namespace: disease_ontology
id: DOID:2493

angiodysplasia
type: Class
subclass of: vascular disease - unclassified by CVDO
imported from: doid.owl
has_alternative_id: DOID:12071
database_cross_reference: MSH:D016888
database_cross_reference: SNOMEDCT_2010_1_31:71072006
database_cross_reference: UMLS_CUI:C0085411
database_cross_reference: UMLS_CUI:C0156091
has_exact_synonym: angiodysplasia of stomach and duodenum with hemorrhage
has_obo_namespace: disease_ontology
id: DOID:2494

intracranial cavernous angioma
type: Class
subclass of: intracranial structure hemangioma
subclass of: cavernous hemangioma
imported from: doid.owl
database_cross_reference: NCI:C5432
database_cross_reference: UMLS_CUI:C1334237
has_exact_synonym: intracranial Cavernoma
has_obo_namespace: disease_ontology
id: DOID:2516

intracranial structure hemangioma
type: Class
subclass of: hemangioma
subclass of: cerebrovascular disease
imported from: doid.owl
database_cross_reference: ICD9CM:228.02
database_cross_reference: NCI:C3633
database_cross_reference: SNOMEDCT_2010_1_31:189196005
database_cross_reference: SNOMEDCT_2010_1_31:93468003
database_cross_reference: UMLS_CUI:C0154050
has_exact_synonym: Angioma of intracranial Structure
has_exact_synonym: hemangioma of intracranial structure (disorder)
has_exact_synonym: hemangioma of intracranial structures
has_exact_synonym: hemangioma of intracranial structures (disorder)
has_obo_namespace: disease_ontology
id: DOID:2517

hemangioma of intra-abdominal structure
type: Class
subclass of: hemangioma
imported from: doid.owl
database_cross_reference: ICD9CM:228.04
database_cross_reference: NCI:C3635
database_cross_reference: SNOMEDCT_2010_1_31:189197001
database_cross_reference: SNOMEDCT_2010_1_31:93467008
database_cross_reference: UMLS_CUI:C0154052
has_exact_synonym: hemangioma of intra-abdominal structure (disorder)
has_exact_synonym: hemangioma of intra-abdominal structures
has_exact_synonym: hemangioma of intra-abdominal structures (disorder)
has_exact_synonym: hemangioma, Intra-abdominal
has_obo_namespace: disease_ontology
id: DOID:254

hemangioma
type: Class
subclass of: vascular disease - unclassified by CVDO
imported from: doid.owl
database_cross_reference: ICD9CM:228.0
database_cross_reference: ICD9CM:228.00
database_cross_reference: MSH:D006391
database_cross_reference: NCI:C3085
database_cross_reference: SNOMEDCT_2010_1_31:154625006
database_cross_reference: SNOMEDCT_2010_1_31:189192007
database_cross_reference: SNOMEDCT_2010_1_31:189193002
database_cross_reference: SNOMEDCT_2010_1_31:189194008
database_cross_reference: SNOMEDCT_2010_1_31:189199003
database_cross_reference: SNOMEDCT_2010_1_31:189863005
database_cross_reference: SNOMEDCT_2010_1_31:2099007
database_cross_reference: SNOMEDCT_2010_1_31:253053003
database_cross_reference: SNOMEDCT_2010_1_31:254822005
database_cross_reference: SNOMEDCT_2010_1_31:269646001
database_cross_reference: SNOMEDCT_2010_1_31:367337005
database_cross_reference: SNOMEDCT_2010_1_31:400210000
database_cross_reference: SNOMEDCT_2010_1_31:93474003
database_cross_reference: UMLS_CUI:C0018916
has_obo_namespace: disease_ontology
id: DOID:255

granulomatous angiitis
type: Class
subclass of: vasculitis
imported from: doid.owl
database_cross_reference: MSH:D020293
database_cross_reference: NCI:C34653
database_cross_reference: UMLS_CUI:C0018202
has_obo_namespace: disease_ontology
id: DOID:2555

hemangioma of liver
type: Class
subclass of: hemangioma of intra-abdominal structure
subclass of: hepatic vascular disease
imported from: doid.owl
database_cross_reference: NCI:C3869
database_cross_reference: SNOMEDCT_2010_1_31:235879002
database_cross_reference: SNOMEDCT_2010_1_31:93469006
database_cross_reference: UMLS_CUI:C0238246
has_exact_synonym: Angioma of Liver
has_exact_synonym: hepatic angioma (disorder)
has_obo_namespace: disease_ontology
id: DOID:271

hepatic vascular disease
type: Class
subclass of: vascular disease - unclassified by CVDO
imported from: doid.owl
database_cross_reference: NCI:C35442
database_cross_reference: SNOMEDCT_2010_1_31:235878005
database_cross_reference: UMLS_CUI:C0400923
has_exact_synonym: vascular disorder of liver (disorder)
has_obo_namespace: disease_ontology
id: DOID:272

arterial occlusive disease
type: Class
subclass of: disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: vascular pathological process
imported from: doid.owl
database_cross_reference: MSH:D001157
database_cross_reference: SNOMEDCT_2010_1_31:2929001
database_cross_reference: UMLS_CUI:C0003838
has_exact_synonym: Arterial occlusive disease
has_obo_namespace: disease_ontology
id: DOID:2868

renal artery obstruction
type: Class
subclass of: arterial occlusive disease
imported from: doid.owl
database_cross_reference: MSH:D012078
database_cross_reference: UMLS_CUI:C0035066
has_exact_synonym: renal artery obstruction
has_obo_namespace: disease_ontology
id: DOID:2972

Churg-Strauss syndrome
type: Class
subclass of: vasculitis
definition: A vasculitits that is systemic vasculitis realized as blood vessel inflammation and has_symptom asthma along with hay fever, rash and gastrointestinal bleeding.
imported from: doid.owl
database_cross_reference: MSH:C531653
database_cross_reference: MSH:D015267
database_cross_reference: NCI:C34481
database_cross_reference: SNOMEDCT_2010_1_31:195362002
database_cross_reference: SNOMEDCT_2010_1_31:82275008
database_cross_reference: UMLS_CUI:C0008728
has_exact_synonym: Allergic Granulomatous Angiitis
has_exact_synonym: Allergic granulomatosis angiitis (disorder)
has_exact_synonym: Churg-Strauss vasculitis
has_obo_namespace: disease_ontology
id: DOID:3049

cervical rib syndrome
type: Class
subclass of: thoracic outlet syndrome
imported from: doid.owl
database_cross_reference: MSH:D002573
database_cross_reference: SNOMEDCT_2010_1_31:413577001
database_cross_reference: SNOMEDCT_2010_1_31:54995001
database_cross_reference: SNOMEDCT_2010_1_31:95409006
database_cross_reference: UMLS_CUI:C0007856
has_exact_synonym: Arterial thoracic outlet syndrome due to cervical rib
has_obo_namespace: disease_ontology
id: DOID:3102

thoracic outlet syndrome
type: Class
subclass of: vascular disease - unclassified by CVDO
imported from: doid.owl
database_cross_reference: MSH:D013901
database_cross_reference: NCI:C85188
database_cross_reference: SNOMEDCT_2010_1_31:128210009
database_cross_reference: SNOMEDCT_2010_1_31:193106006
database_cross_reference: SNOMEDCT_2010_1_31:193107002
database_cross_reference: SNOMEDCT_2010_1_31:193108007
database_cross_reference: SNOMEDCT_2010_1_31:2040007
database_cross_reference: SNOMEDCT_2010_1_31:212769008
database_cross_reference: SNOMEDCT_2010_1_31:393578000
database_cross_reference: UMLS_CUI:C0039984
has_exact_synonym: TOS - Thoracic outlet syndrome
has_obo_namespace: disease_ontology
id: DOID:3103

spinal cord ischemia
type: Class
subclass of: ischemia
CVDO definition: An ischemia occurring in the spinal cord.
imported from: doid.owl
database_cross_reference: MSH:D020760
database_cross_reference: SNOMEDCT_2010_1_31:371029002
database_cross_reference: UMLS_CUI:C0752130
has_exact_synonym: Ischaemic disorder of spinal cord
has_obo_namespace: disease_ontology
id: DOID:324

spinal cord vascular disease
type: Class
subclass of: vascular disease - unclassified by CVDO
imported from: doid.owl
database_cross_reference: MSH:D020758
database_cross_reference: UMLS_CUI:C0752127
has_obo_namespace: disease_ontology
id: DOID:325

ischemia
type: Class
subclass of: pathological bodily process
subclass of: Restriction
  on property: occurs in
  some values from: Vascular tree
CVDO definition: A pathological process of restriction in blood supply to tissues, causing a shortage of oxygen and glucose needed for cellular metabolism.
imported from: doid.owl
database_cross_reference: MSH:D007511
database_cross_reference: NCI:C34738
database_cross_reference: SNOMEDCT_2010_1_31:52674009
database_cross_reference: UMLS_CUI:C0022116
has_exact_synonym: ischemia
has_obo_namespace: disease_ontology
id: DOID:326

coronary aneurysm
type: Class
subclass of: aneurysm (disease)
imported from: doid.owl
database_cross_reference: ICD9CM:414.11
database_cross_reference: MSH:D003323
database_cross_reference: SNOMEDCT_2010_1_31:373139003
database_cross_reference: SNOMEDCT_2010_1_31:50570003
database_cross_reference: UMLS_CUI:C0010051
has_exact_synonym: Aneurysm of coronary vessels
has_exact_synonym: Aneurysmal lesion of coronary artery
has_exact_synonym: Arteriovenous aneurysm of coronary vessels
has_obo_namespace: disease_ontology
id: DOID:3362
label: coronary aneurysm disease

coronary arteriosclerosis
type: Class
equivalent class: Class
  intersection of: arteriosclerosis
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: coronary artery hardening
imported from: doid.owl
database_cross_reference: ICD9CM:414.0
database_cross_reference: MSH:D003324
database_cross_reference: NCI:C35505
database_cross_reference: SNOMEDCT_2010_1_31:155315001
database_cross_reference: SNOMEDCT_2010_1_31:155316000
database_cross_reference: SNOMEDCT_2010_1_31:194795001
database_cross_reference: SNOMEDCT_2010_1_31:194841001
database_cross_reference: SNOMEDCT_2010_1_31:266231003
database_cross_reference: SNOMEDCT_2010_1_31:266290000
database_cross_reference: SNOMEDCT_2010_1_31:41702007
database_cross_reference: SNOMEDCT_2010_1_31:53741008
database_cross_reference: UMLS_CUI:C0010054
has_obo_namespace: disease_ontology
id: DOID:3363

coronary heart disease
type: Class
subclass of: ischemic heart disease
CVDO definition: An ischemic heart disease with narrowing of the coronary arteries.
imported from: doid.owl
database_cross_reference: MSH:D003327
database_cross_reference: NCI:C26732
database_cross_reference: SNOMEDCT_2010_1_31:41702007
database_cross_reference: SNOMEDCT_2010_1_31:53741008
database_cross_reference: UMLS_CUI:C0010068
has_exact_synonym: CHD (coronary heart disease)
has_exact_synonym: CHD - Coronary heart disease
has_exact_synonym: Coronary disease
has_obo_namespace: disease_ontology
id: DOID:3393

ischemic heart disease
type: Class
subclass of: disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: heart pathological process
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: heart ischemia
CVDO definition: A disease characterized by reduced blood supply to the heart, occasioning pathological processes in the heart.
definition: An extrinsic cardiomyopathy that is characterized by reduced blood supply to the cardiac muscles.
imported from: doid.owl
has_alternative_id: DOID:10506
has_alternative_id: DOID:9420
database_cross_reference: ICD9CM:410-414.99
database_cross_reference: ICD9CM:414.9
database_cross_reference: MSH:D017202
database_cross_reference: NCI:C50625
database_cross_reference: SNOMEDCT_2010_1_31:155303000
database_cross_reference: SNOMEDCT_2010_1_31:155315001
database_cross_reference: SNOMEDCT_2010_1_31:155318004
database_cross_reference: SNOMEDCT_2010_1_31:155322009
database_cross_reference: SNOMEDCT_2010_1_31:194795001
database_cross_reference: SNOMEDCT_2010_1_31:194852007
database_cross_reference: SNOMEDCT_2010_1_31:194878003
database_cross_reference: SNOMEDCT_2010_1_31:195540001
database_cross_reference: SNOMEDCT_2010_1_31:233822007
database_cross_reference: SNOMEDCT_2010_1_31:2610009
database_cross_reference: SNOMEDCT_2010_1_31:266290000
database_cross_reference: SNOMEDCT_2010_1_31:266291001
database_cross_reference: SNOMEDCT_2010_1_31:271430002
database_cross_reference: SNOMEDCT_2010_1_31:32598000
database_cross_reference: SNOMEDCT_2010_1_31:413838009
database_cross_reference: SNOMEDCT_2010_1_31:413844008
database_cross_reference: SNOMEDCT_2010_1_31:414545008
database_cross_reference: SNOMEDCT_2010_1_31:414795007
database_cross_reference: SNOMEDCT_2010_1_31:41702007
database_cross_reference: SNOMEDCT_2010_1_31:84537008
database_cross_reference: UMLS_CUI:C0151744
database_cross_reference: UMLS_CUI:C0264694
has_exact_synonym: chronic myocardial ischaemia
has_exact_synonym: myocardial ischemia
has_obo_namespace: disease_ontology
id: DOID:3394

carotid artery disease
type: Class
subclass of: cerebrovascular disease
imported from: doid.owl
database_cross_reference: MSH:D002340
database_cross_reference: NCI:C84476
database_cross_reference: SNOMEDCT_2010_1_31:371160000
database_cross_reference: UMLS_CUI:C0007273
has_exact_synonym: disorder of carotid artery (disorder)
has_obo_namespace: disease_ontology
id: DOID:3407

peripheral vascular disease
type: Class
subclass of: ischemic disease
imported from: doid.owl
database_cross_reference: ICD9CM:443.81
database_cross_reference: SNOMEDCT_2010_1_31:195624006
database_cross_reference: UMLS_CUI:C0031115
has_obo_namespace: disease_ontology
id: DOID:341

carotid artery thrombosis
type: Class
subclass of: intracranial thrombosis
subclass of: Restriction
  on property: occurs in
  some values from: Common carotid artery
CVDO definition: A thrombosis occurring in a carotid artery.
imported from: doid.owl
database_cross_reference: MSH:D002341
database_cross_reference: SNOMEDCT_2010_1_31:195181000
database_cross_reference: SNOMEDCT_2010_1_31:86003009
database_cross_reference: UMLS_CUI:C0007274
has_exact_synonym: Carotid artery thrombosis
has_exact_synonym: Carotid artery thrombosis (disorder)
has_obo_namespace: disease_ontology
id: DOID:3410

subclavian artery aneurysm
type: Class
subclass of: aneurysm (disease)
imported from: doid.owl
database_cross_reference: ICD9CM:442.82
database_cross_reference: SNOMEDCT_2010_1_31:40136003
database_cross_reference: UMLS_CUI:C0155746
has_obo_namespace: disease_ontology
id: DOID:342
label: subclavian artery aneurysm disease

brain infarction
type: Class
equivalent class: Class
  intersection of: infarction
  intersection of: Restriction
    on property: occurs in
    some values from: Brain
imported from: doid.owl
database_cross_reference: MSH:D020520
database_cross_reference: UMLS_CUI:C0751955
has_obo_namespace: disease_ontology
id: DOID:3454
comment: An infarction occurring in the brain.

cerebrovascular accident
type: Class
subclass of: pathological bodily process
subclass of: Restriction
  on property: occurs in
  some values from: Arterial tree organ
CVDO definition: A pathological process of disturbance in the blood supply to the brain, causing a loss of brain function.
imported from: doid.owl
database_cross_reference: MSH:D020521
database_cross_reference: NCI:C3390
database_cross_reference: OMIM:601367
database_cross_reference: SNOMEDCT_2010_1_31:155388006
database_cross_reference: SNOMEDCT_2010_1_31:155405006
database_cross_reference: SNOMEDCT_2010_1_31:195208004
database_cross_reference: SNOMEDCT_2010_1_31:230690007
database_cross_reference: SNOMEDCT_2010_1_31:266312006
database_cross_reference: SNOMEDCT_2010_1_31:266315008
database_cross_reference: SNOMEDCT_2010_1_31:270883006
database_cross_reference: SNOMEDCT_2010_1_31:313267000
database_cross_reference: SNOMEDCT_2010_1_31:82797006
database_cross_reference: UMLS_CUI:C0038454
has_exact_synonym: CVA (cerebral vascular accident)
has_exact_synonym: CVA - Cerebrovascular accident unspecified
has_exact_synonym: Cerebrovascular accident (disorder)
has_exact_synonym: Cerebrovascular accident (disorder) [Ambiguous]
has_obo_namespace: disease_ontology
has_related_synonym: Stroke
id: DOID:3455
comment: OMIM mapping confirmed by DO. [SN].

lateral medullary syndrome
type: Class
subclass of: brain stem infarction
imported from: doid.owl
database_cross_reference: MSH:D014854
database_cross_reference: NCI:C84807
database_cross_reference: SNOMEDCT_2010_1_31:195193009
database_cross_reference: SNOMEDCT_2010_1_31:78569004
database_cross_reference: UMLS_CUI:C0043019
has_exact_synonym: Posterior inferior cerebellar artery syndrome (disorder)
has_exact_synonym: Wallenberg syndrome
has_obo_namespace: disease_ontology
id: DOID:3522

brain stem infarction
type: Class
subclass of: brain infarction
imported from: doid.owl
database_cross_reference: MSH:D020526
database_cross_reference: SNOMEDCT_2010_1_31:195191006
database_cross_reference: SNOMEDCT_2010_1_31:195192004
database_cross_reference: SNOMEDCT_2010_1_31:230697005
database_cross_reference: SNOMEDCT_2010_1_31:95457000
database_cross_reference: UMLS_CUI:C0521542
has_exact_synonym: Brainstem infarction
has_exact_synonym: Brainstem infarction NOS
has_exact_synonym: Brainstem infarction NOS (disorder)
has_exact_synonym: brain stem infarction (disorder)
has_obo_namespace: disease_ontology
id: DOID:3523

middle cerebral artery infarction
type: Class
subclass of: cerebral infarction
imported from: doid.owl
database_cross_reference: MSH:D020244
database_cross_reference: UMLS_CUI:C0740392
has_obo_namespace: disease_ontology
id: DOID:3525

cerebral infarction
type: Class
subclass of: brain infarction
imported from: doid.owl
database_cross_reference: MSH:D002544
database_cross_reference: NCI:C50486
database_cross_reference: SNOMEDCT_2010_1_31:155405006
database_cross_reference: SNOMEDCT_2010_1_31:195188006
database_cross_reference: SNOMEDCT_2010_1_31:195191006
database_cross_reference: SNOMEDCT_2010_1_31:20059004
database_cross_reference: SNOMEDCT_2010_1_31:266256009
database_cross_reference: SNOMEDCT_2010_1_31:266315008
database_cross_reference: SNOMEDCT_2010_1_31:432504007
database_cross_reference: UMLS_CUI:C0007785
has_exact_synonym: CVA - Cerebral infarction
has_exact_synonym: Cerebral infarct
has_exact_synonym: Cerebral infarction
has_exact_synonym: Cerebral infarction NOS
has_exact_synonym: Cerebral infarction NOS (disorder)
has_obo_namespace: disease_ontology
id: DOID:3526

cerebral arterial disease
type: Class
subclass of: intracranial arterial disease
imported from: doid.owl
database_cross_reference: MSH:D002539
database_cross_reference: UMLS_CUI:C0007774
has_obo_namespace: disease_ontology
id: DOID:3527

anterior cerebral artery infarction
type: Class
subclass of: cerebral infarction
imported from: doid.owl
database_cross_reference: MSH:D020243
database_cross_reference: UMLS_CUI:C0751843
has_obo_namespace: disease_ontology
id: DOID:3528

intracranial sinus thrombosis
type: Class
subclass of: intracranial thrombosis
subclass of: Restriction
  on property: occurs in
  some values from: Dural venous sinus
CVDO definition: A thrombosis that occurs in a dural venous sinus.
imported from: doid.owl
database_cross_reference: MSH:D012851
database_cross_reference: UMLS_CUI:C0037198
has_obo_namespace: disease_ontology
id: DOID:3572

lateral sinus thrombosis
type: Class
subclass of: intracranial sinus thrombosis
subclass of: Restriction
  on property: occurs in
  some values from: Transverse sinus
CVDO definition: A thrombosis that occurs in a transverse sinus.
imported from: doid.owl
database_cross_reference: MSH:D020227
database_cross_reference: SNOMEDCT_2010_1_31:192761004
database_cross_reference: SNOMEDCT_2010_1_31:21258007
database_cross_reference: UMLS_CUI:C0270639
has_exact_synonym: Thrombosis of lateral venous sinus (disorder)
has_exact_synonym: Thrombosis transverse sinus (disorder)
has_obo_namespace: disease_ontology
id: DOID:3574

cavernous sinus thrombosis
type: Class
subclass of: intracranial sinus thrombosis
CVDO definition: A thrombosis that occurs in a cavernous sinus.
imported from: doid.owl
database_cross_reference: MSH:D020226
database_cross_reference: SNOMEDCT_2010_1_31:89980009
database_cross_reference: UMLS_CUI:C0238454
has_exact_synonym: Thrombosis of cavernous venous sinus (disorder)
has_obo_namespace: disease_ontology
id: DOID:3575

sagittal sinus thrombosis
type: Class
subclass of: intracranial sinus thrombosis
imported from: doid.owl
database_cross_reference: MSH:D020225
database_cross_reference: SNOMEDCT_2010_1_31:192760003
database_cross_reference: SNOMEDCT_2010_1_31:70607008
database_cross_reference: UMLS_CUI:C0338575
has_exact_synonym: Thrombosis of superior longitudinal sinus (disorder)
has_exact_synonym: Thrombosis of superior sagittal sinus (disorder)
has_obo_namespace: disease_ontology
id: DOID:3576

aortic aneurysm
type: Class
subclass of: aneurysm (disease)
imported from: doid.owl
database_cross_reference: MSH:D001014
database_cross_reference: NCI:C26697
database_cross_reference: SNOMEDCT_2010_1_31:155419006
database_cross_reference: SNOMEDCT_2010_1_31:155424009
database_cross_reference: SNOMEDCT_2010_1_31:195269009
database_cross_reference: SNOMEDCT_2010_1_31:67362008
database_cross_reference: UMLS_CUI:C0003486
has_obo_namespace: disease_ontology
id: DOID:3627
label: aortic aneurysm disease

intermittent claudication
type: Class
subclass of: vascular disease - unclassified by CVDO
imported from: doid.owl
database_cross_reference: MSH:D007383
database_cross_reference: SNOMEDCT_2010_1_31:155430009
database_cross_reference: SNOMEDCT_2010_1_31:195312007
database_cross_reference: SNOMEDCT_2010_1_31:63491006
database_cross_reference: UMLS_CUI:C0021775
has_exact_synonym: Charcot's syndrome
has_exact_synonym: Intermittent claudication
has_exact_synonym: Intermittent claudication (disorder)
has_exact_synonym: Intermittent claudication NOS
has_obo_namespace: disease_ontology
id: DOID:3669

posterior cerebral artery infarction
type: Class
subclass of: cerebral infarction
imported from: doid.owl
database_cross_reference: MSH:D020762
database_cross_reference: UMLS_CUI:C0752132
has_obo_namespace: disease_ontology
id: DOID:3821

Shwartzman phenomenon
type: Class
subclass of: vascular disease - unclassified by CVDO
subclass of: vascular hemostatic disease
imported from: doid.owl
database_cross_reference: MSH:D012790
database_cross_reference: SNOMEDCT_2010_1_31:24453002
database_cross_reference: UMLS_CUI:C0037018
has_exact_synonym: Shwartzman phenomenon
has_exact_synonym: Shwartzman reaction (function)
has_obo_namespace: disease_ontology
id: DOID:3825

Wolff-Parkinson-White syndrome
type: Class
equivalent class: Class
  intersection of: heart conduction disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: ventricular preexcitation (process)
      intersection of: Restriction
        on property: has occurrent part
        some values from: atrioventricular reciprocating tachycardia (process)
  intersection of: Restriction
    on property: has material basis at all times
    some values from: atrioventricular accessory bundle
imported from: doid.owl
database_cross_reference: MSH:D014927
database_cross_reference: NCI:C35132
database_cross_reference: OMIM:194200
database_cross_reference: SNOMEDCT_2010_1_31:155360000
database_cross_reference: SNOMEDCT_2010_1_31:251115003
database_cross_reference: SNOMEDCT_2010_1_31:266304003
database_cross_reference: SNOMEDCT_2010_1_31:74390002
database_cross_reference: UMLS_CUI:C0043202
has_exact_synonym: Wolff Parkinson White syndrome
has_exact_synonym: Wolff-Park-White syndr.
has_exact_synonym: Wolff-Parkinson-White pattern (disorder)
has_exact_synonym: Wolff-Parkinson-White pattern (finding)
has_exact_synonym: Wolff-Parkinson-White syndrome
has_obo_namespace: disease_ontology
id: DOID:384

thrombophlebitis
type: Class
subclass of: disease
subclass of: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: inflammation process in a vein
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: thrombosis
imported from: doid.owl
has_alternative_id: DOID:1146
database_cross_reference: MSH:D013924
database_cross_reference: NCI:C3410
database_cross_reference: SNOMEDCT_2010_1_31:195401008
database_cross_reference: SNOMEDCT_2010_1_31:195433004
database_cross_reference: SNOMEDCT_2010_1_31:266266001
database_cross_reference: SNOMEDCT_2010_1_31:40283005
database_cross_reference: SNOMEDCT_2010_1_31:64156001
database_cross_reference: UMLS_CUI:C0040046
database_cross_reference: UMLS_CUI:C0265057
has_exact_synonym: Phlebitis and thrombophlebitis of superficial vessels of lower extremities
has_exact_synonym: Superficial thrombophlebitis of leg
has_exact_synonym: Superficial thrombophlebitis of leg (disorder)
has_exact_synonym: Thrombophlebitis (disorder)
has_exact_synonym: Thrombophlebitis NOS (disorder)
has_exact_synonym: Thrombophlebitis of a superficial leg vein NOS (disorder)
has_exact_synonym: Thrombophlebitis of superficial veins of lower extremity (disorder)
has_exact_synonym: thrombophlebitis
has_obo_namespace: disease_ontology
id: DOID:3875

anterior compartment syndrome
type: Class
subclass of: compartment syndrome
imported from: doid.owl
database_cross_reference: MSH:D000868
database_cross_reference: SNOMEDCT_2010_1_31:157669006
database_cross_reference: SNOMEDCT_2010_1_31:212379008
database_cross_reference: SNOMEDCT_2010_1_31:269407005
database_cross_reference: UMLS_CUI:C0003152
has_exact_synonym: Anterior compartment syndrome
has_obo_namespace: disease_ontology
id: DOID:3933

acute myocarditis
type: Class
equivalent class: Class
  intersection of: myocarditis
  intersection of: Restriction
    on property: realized in
    some values from: acute disease course
CVDO definition: A myocarditis with an acute disease course.
imported from: doid.owl
database_cross_reference: ICD9CM:422
database_cross_reference: ICD9CM:422.90
database_cross_reference: NCI:C35206
database_cross_reference: SNOMEDCT_2010_1_31:155336004
database_cross_reference: SNOMEDCT_2010_1_31:194953001
database_cross_reference: SNOMEDCT_2010_1_31:194961006
database_cross_reference: SNOMEDCT_2010_1_31:195569005
database_cross_reference: SNOMEDCT_2010_1_31:46701001
database_cross_reference: UMLS_CUI:C0155686
has_obo_namespace: disease_ontology
id: DOID:3951

Loeffler endocarditis
type: Class
subclass of: restrictive cardiomyopathy
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: progressive disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: inflammation process in an endocardium
definition: A restrictive cardiomyopathy that affects the endocardium and occurs with white blood cell proliferation, specifically of eosinophils.
imported from: doid.owl
database_cross_reference: NCI:C27044
database_cross_reference: SNOMEDCT_2010_1_31:33258008
database_cross_reference: UMLS_CUI:C0264834
has_exact_synonym: Eosinophilic Endomyocardial disease
has_obo_namespace: disease_ontology
id: DOID:396

restrictive cardiomyopathy
type: Class
subclass of: disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: progressive disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: left ventricular myocardium contraction dysfunctional process
    intersection of: Restriction
      on property: has occurrent part
      some values from: myocardium of left ventricle stiffening
CVDO definition: A cardiomyopathy (2008) characterized by increased stiffness of the left ventricular myocardium and decreased compliance of the left ventricle (which is restricted from stretching and filling with blood properly), in the absence of dilated cardiomyopathy and hypertrophic cardiomyopathy.
imported from: doid.owl
database_cross_reference: MSH:D002313
database_cross_reference: NCI:C62798
database_cross_reference: SNOMEDCT_2010_1_31:389996009
database_cross_reference: SNOMEDCT_2010_1_31:415295002
database_cross_reference: SNOMEDCT_2010_1_31:90828009
database_cross_reference: UMLS_CUI:C0007196
has_exact_synonym: Cardiomyopathy, constrictive
has_exact_synonym: Restrictive cardiomyopathy
has_exact_synonym: Restrictive cardiomyopathy (disorder)
has_exact_synonym: primary restrictive cardiomyopathy (disorder)
has_obo_namespace: disease_ontology
id: DOID:397

angioma serpiginosum
type: Class
subclass of: telangiectasis
subclass of: skin hemangioma
imported from: doid.owl
database_cross_reference: MSH:C536366
database_cross_reference: NCI:C3926
database_cross_reference: SNOMEDCT_2010_1_31:11790000
database_cross_reference: SNOMEDCT_2010_1_31:195382003
database_cross_reference: SNOMEDCT_2010_1_31:49465005
database_cross_reference: UMLS_CUI:C0263637
has_exact_synonym: Angioma Serpiginosum
has_exact_synonym: Angioma serpiginosum (disorder)
has_exact_synonym: Angioma serpiginosum of skin
has_obo_namespace: disease_ontology
id: DOID:4028

tricuspid valve stenosis
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: tricuspid valve narrowed opening during right ventricular diastole
  intersection of: Restriction
    on property: has material basis at all times
    some values from: tricuspid valve disorder
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: disturbed anterograd blood flow through tricuspid valve during right ventricular diastole
CVDO definition: A disease in which some disorder of a tricuspid valve prevents it from opening properly during right ventricular diastole, occasioning disturbance in the anterograd blood flow through the valve.
definition: A heart valve disease which results in the narrowing of the orifice of the tricuspid valve of the heart. This causes increased resistance to blood flow through the valve. It is almost always caused by rheumatic fever and is generally accompanied by mitral stenosis. Rare other causes include carcinoid syndrome, endocarditis, endomyocardial fibrosis, lupus erythematosus, right atrial myxoma and congenital tricuspid atresia.
imported from: doid.owl
database_cross_reference: MSH:D014264
database_cross_reference: NCI:C50783
database_cross_reference: SNOMEDCT_2010_1_31:155346002
database_cross_reference: SNOMEDCT_2010_1_31:266296006
database_cross_reference: SNOMEDCT_2010_1_31:49915006
database_cross_reference: UMLS_CUI:C0040963
has_exact_synonym: Tricuspid stenosis
has_exact_synonym: Tricuspid valve stenosis (disorder)
has_obo_namespace: disease_ontology
id: DOID:4078

heart valve disease
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Class
    union of: Restriction
      on property: realized in
      some values from: Class
        intersection of: disease course
        intersection of: Restriction
    union of: Restriction
      on property: has material basis at all times
      some values from: heart valve disorder
CVDO definition: A disease affecting a valve of the heart.
definition: Heart valve disease is a heart disease described as any disease process involving one or more of the valves of the heart (the aortic and mitral valves on the left and the pulmonary and tricuspid valves on the right). Valve problems may be congenital (inborn) or acquired (due to another cause later in life).
imported from: doid.owl
database_cross_reference: MSH:D006349
database_cross_reference: NCI:C45525
database_cross_reference: SNOMEDCT_2010_1_31:195013005
database_cross_reference: SNOMEDCT_2010_1_31:368009
database_cross_reference: UMLS_CUI:C0018824
has_exact_synonym: Valvular heart disease (disorder)
has_obo_namespace: disease_ontology
id: DOID:4079

tricuspid valve insufficiency
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: tricuspid valve improper close during right ventricular systole
  intersection of: Restriction
    on property: has material basis at all times
    some values from: tricuspid valve disorder
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: retrograd blood flow through tricuspid valve during right ventricular systole
CVDO definition: A disease in which an abnormal structure in a mitral valve prevents it to close propertly during systole, occasioning a retrograd blood flow through the valve.
definition: A heart valve disease where the heart's tricuspid valve fails to close properly during systole. As a result, with each heart beat, blood is pumped out from the right side of the heart in the opposite direction to normal.
imported from: doid.owl
database_cross_reference: MSH:D014262
database_cross_reference: NCI:C50842
database_cross_reference: NCI:C50843
database_cross_reference: SNOMEDCT_2010_1_31:111287006
database_cross_reference: SNOMEDCT_2010_1_31:155347006
database_cross_reference: SNOMEDCT_2010_1_31:251009000
database_cross_reference: SNOMEDCT_2010_1_31:266298007
database_cross_reference: UMLS_CUI:C0040961
has_exact_synonym: Tricuspid incompetence
has_exact_synonym: Tricuspid regurgitation
has_exact_synonym: Tricuspid valve regurgitation (disorder)
has_obo_namespace: disease_ontology
id: DOID:4080

intracranial thrombosis
type: Class
subclass of: thrombosis
subclass of: Restriction
  on property: occurs in
  some values from: Brain
CVDO definition: A thrombosis occurring in the brain.
imported from: doid.owl
has_alternative_id: DOID:12751
database_cross_reference: ICD9CM:434.0
database_cross_reference: MSH:D020767
database_cross_reference: SNOMEDCT_2010_1_31:155401002
database_cross_reference: UMLS_CUI:C0079102
database_cross_reference: UMLS_CUI:C0752143
has_exact_synonym: cerebral thrombosis
has_obo_namespace: disease_ontology
id: DOID:4193

coronary restenosis
type: Class
subclass of: coronary stenosis
imported from: doid.owl
database_cross_reference: MSH:D023903
database_cross_reference: UMLS_CUI:C0948480
has_obo_namespace: disease_ontology
id: DOID:4247

coronary stenosis
type: Class
subclass of: disorder
subclass of: Restriction
  on property: located in at all times
  some values from: Coronary artery
CVDO definition: A disorder of atheromous plaques in a coronary artery.
imported from: doid.owl
database_cross_reference: MSH:D023921
database_cross_reference: NCI:C80427
database_cross_reference: SNOMEDCT_2010_1_31:233970002
database_cross_reference: UMLS_CUI:C0242231
has_exact_synonym: Coronary artery stenosis (disorder)
has_obo_namespace: disease_ontology
id: DOID:4248

intracranial embolism
type: Class
subclass of: embolism
subclass of: Restriction
  on property: occurs in
  some values from: Class
    intersection of: Vascular tree
    intersection of: Restriction
      on property: located in at all times
      some values from: Brain
imported from: doid.owl
has_alternative_id: DOID:1957
has_alternative_id: DOID:1958
database_cross_reference: ICD9CM:434.1
database_cross_reference: MSH:D020766
database_cross_reference: SNOMEDCT_2010_1_31:155402009
database_cross_reference: SNOMEDCT_2010_1_31:75543006
database_cross_reference: UMLS_CUI:C0007780
database_cross_reference: UMLS_CUI:C0752140
has_exact_synonym: Cerebral embolism with cerebral infarction
has_exact_synonym: cerebral embolism
has_obo_namespace: disease_ontology
id: DOID:4372

subacute bacterial endocarditis
type: Class
subclass of: bacterial endocarditis
CVDO definition: A bacterial endocarditis characterized by a slow process of infection.
imported from: doid.owl
database_cross_reference: MSH:D004698
database_cross_reference: NCI:C34583
database_cross_reference: SNOMEDCT_2010_1_31:155334001
database_cross_reference: SNOMEDCT_2010_1_31:194923008
database_cross_reference: SNOMEDCT_2010_1_31:50194006
database_cross_reference: SNOMEDCT_2010_1_31:73774007
database_cross_reference: UMLS_CUI:C0014122
has_exact_synonym: Endocarditis lenta
has_exact_synonym: SBE - Subacute bacterial endocarditis
has_exact_synonym: Subacute bacterial endocarditis
has_exact_synonym: Subacute bacterial endocarditis (disorder)
has_exact_synonym: Subacute endocarditis, lenta
has_obo_namespace: disease_ontology
id: DOID:4562
in_subset: gram-positive bacterial infectious disease

skin hemangioma
type: Class
subclass of: hemangioma
imported from: doid.owl
database_cross_reference: NCI:C4905
database_cross_reference: SNOMEDCT_2010_1_31:189195009
database_cross_reference: SNOMEDCT_2010_1_31:254773009
database_cross_reference: SNOMEDCT_2010_1_31:93471006
database_cross_reference: UMLS_CUI:C0687140
has_exact_synonym: Angioma of the skin
has_exact_synonym: Angiomatous naevus of skin
has_exact_synonym: hemangioma of skin (disorder)
has_exact_synonym: skin hemangioma
has_obo_namespace: disease_ontology
id: DOID:471

cavernous hemangioma
type: Class
subclass of: vascular hemostatic disease
imported from: doid.owl
database_cross_reference: MSH:D006392
database_cross_reference: NCI:C3086
database_cross_reference: SNOMEDCT_2010_1_31:157014007
database_cross_reference: SNOMEDCT_2010_1_31:189192007
database_cross_reference: SNOMEDCT_2010_1_31:254781005
database_cross_reference: SNOMEDCT_2010_1_31:33377007
database_cross_reference: SNOMEDCT_2010_1_31:416824008
database_cross_reference: SNOMEDCT_2010_1_31:56975005
database_cross_reference: SNOMEDCT_2010_1_31:67668002
database_cross_reference: UMLS_CUI:C0018920
has_exact_synonym: Cavernoma
has_exact_synonym: Cavernous haemangioma (disorder)
has_exact_synonym: Cavernous hemangioma (morphologic abnormality)
has_obo_namespace: disease_ontology
id: DOID:483

vascular hemostatic disease
type: Class
subclass of: vascular disease - unclassified by CVDO
imported from: doid.owl
database_cross_reference: MSH:D020141
database_cross_reference: SNOMEDCT_2010_1_31:21112004
database_cross_reference: UMLS_CUI:C0600502
has_obo_namespace: disease_ontology
id: DOID:484

arteriosclerosis obliterans
type: Class
subclass of: arteriosclerosis
imported from: doid.owl
database_cross_reference: MSH:D001162
database_cross_reference: SNOMEDCT_2010_1_31:361133006
database_cross_reference: SNOMEDCT_2010_1_31:60625000
database_cross_reference: UMLS_CUI:C0003851
has_exact_synonym: Arteriosclerosis obliterans (disorder)
has_exact_synonym: Arteriosclerosis obliterans (disorder) [Ambiguous]
has_obo_namespace: disease_ontology
id: DOID:5160

Monckeberg arteriosclerosis
type: Class
subclass of: arteriosclerosis
imported from: doid.owl
database_cross_reference: UMLS_CUI:C0544830
has_obo_namespace: disease_ontology
id: DOID:5161

arteriolosclerosis
type: Class
subclass of: arteriosclerosis
imported from: doid.owl
database_cross_reference: MSH:D050379
database_cross_reference: NCI:C35543
database_cross_reference: SNOMEDCT_2010_1_31:17941002
database_cross_reference: UMLS_CUI:C0878486
has_exact_synonym: Arteriolosclerosis (morphologic abnormality)
has_obo_namespace: disease_ontology
id: DOID:5162

aortitis
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: inflammation process in aorta
CVDO definition: A disease characterized by an inflammation of the aorta.
imported from: doid.owl
database_cross_reference: MSH:D001025
database_cross_reference: SNOMEDCT_2010_1_31:195368003
database_cross_reference: SNOMEDCT_2010_1_31:70933002
database_cross_reference: UMLS_CUI:C0003509
has_exact_synonym: Aortitis (disorder)
has_exact_synonym: Aortitis NOS
has_obo_namespace: disease_ontology
id: DOID:519

aortic disease
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Class
    union of: Restriction
      on property: realized in
      some values from: Class
        intersection of: disease course
        intersection of: Restriction
    union of: Restriction
      on property: has material basis at all times
      some values from: aorta disorder
CVDO definition: A disease affecting the aorta.
imported from: doid.owl
database_cross_reference: MSH:D001018
database_cross_reference: SNOMEDCT_2010_1_31:47040006
database_cross_reference: UMLS_CUI:C0003493
has_exact_synonym: aortic disorder
has_exact_synonym: disorder of the aorta (disorder)
has_obo_namespace: disease_ontology
id: DOID:520

aortic valve prolapse
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: aortic valve leaflet displacement into the left ventricle during left ventricular diastole
  intersection of: Restriction
    on property: has material basis at all times
    some values from: degenerated structure in an aortic valve leaflet
CVDO definition: A disease characterized by the displacement of a degenerated aortic valve leaflet into the left ventricle during diastole.
imported from: doid.owl
database_cross_reference: MSH:D001023
database_cross_reference: UMLS_CUI:C0003505
has_obo_namespace: disease_ontology
id: DOID:5232

central nervous system vasculitis
type: Class
subclass of: disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: inflammation process in a blood vessel
imported from: doid.owl
database_cross_reference: MSH:D020293
database_cross_reference: NCI:C84622
database_cross_reference: UMLS_CUI:C0751878
has_obo_namespace: disease_ontology
id: DOID:525

brain angioma
type: Class
subclass of: intracranial structure hemangioma
imported from: doid.owl
database_cross_reference: NCI:C7739
database_cross_reference: UMLS_CUI:C0238814
has_obo_namespace: disease_ontology
id: DOID:5393

aortic incompetence
type: Class
subclass of: aortic valve insufficiency
definition: Aortic incompetence is a aortic valve disease where leakage of blood from the aorta back into the left ventricle during diastole because of failure of an aortic valve to close properly.
imported from: doid.owl
database_cross_reference: ICD9CM:396.3
database_cross_reference: SNOMEDCT_2010_1_31:194736003
database_cross_reference: SNOMEDCT_2010_1_31:59464004
database_cross_reference: UMLS_CUI:C0264774
has_obo_namespace: disease_ontology
has_related_synonym: Corrigan's disease
id: DOID:54

pulmonary venoocclusive disease
type: Class
subclass of: vascular disease - unclassified by CVDO
imported from: doid.owl
database_cross_reference: MSH:D011668
database_cross_reference: NCI:C85039
database_cross_reference: OMIM:265450
database_cross_reference: SNOMEDCT_2010_1_31:89420002
database_cross_reference: UMLS_CUI:C0034091
has_exact_synonym: pulmonary veno-occlusive disease (disorder)
has_obo_namespace: disease_ontology
id: DOID:5453
comment: OMIM mapping confirmed by DO. [SN].

rheumatic aortic valve insufficiency
type: Class
subclass of: aortic valve insufficiency
CVDO definition: An aortic valve insufficiency due to rheumatic fever.
imported from: doid.owl
database_cross_reference: ICD9CM:395.1
database_cross_reference: SNOMEDCT_2010_1_31:155283004
database_cross_reference: SNOMEDCT_2010_1_31:78031003
database_cross_reference: UMLS_CUI:C0155568
has_exact_synonym: Rheumatic aortic insufficiency
has_exact_synonym: Rheumatic aortic regurgitation
has_exact_synonym: Rheumatic aortic regurgitation (disorder)
has_exact_synonym: Rheumatic aortic valve regurgitation
has_obo_namespace: disease_ontology
id: DOID:55

tricuspid valve prolapse
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: tricuspid valve leaflet displacement into the right atrium during right ventricular systole
  intersection of: Restriction
    on property: has material basis at all times
    some values from: degenerated structure in a tricuspid valve leaflet
CVDO definition: A disease characterized by the displacement of a degenerated tricuspid valve leaflet into the right atrium during systole.
imported from: doid.owl
database_cross_reference: MSH:D014263
database_cross_reference: SNOMEDCT_2010_1_31:253383003
database_cross_reference: UMLS_CUI:C0040962
has_exact_synonym: Tricuspid valve prolapse (disorder)
has_obo_namespace: disease_ontology
id: DOID:5644

aortic valve insufficiency
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: aortic valve improper close during left ventricular diastole
  intersection of: Restriction
    on property: has material basis at all times
    some values from: aortic valve disorder
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: retrograd blood flow through aortic valve during left ventricular diastole
CVDO definition: A disease in which an abnormal structure in an aortic valve prevents it to close propertly during diastole, occasioning a retrograd blood flow through the valve.
definition: Aortic valve insufficiency is a aortic valve disease where leaking of the aortic valve of the heart causes blood to flow in the reverse direction during ventricular diastole, from the aorta into the left ventricle. Aortic insufficiency can be due to abnormalities of either the aortic valve or the aortic root (the beginning of the aorta).
imported from: doid.owl
database_cross_reference: MSH:D001022
database_cross_reference: NCI:C50861
database_cross_reference: NCI:C51223
database_cross_reference: SNOMEDCT_2010_1_31:60234000
database_cross_reference: UMLS_CUI:C0003504
has_exact_synonym: Aortic valve regurgitation (disorder)
has_exact_synonym: aortic insufficiency
has_exact_synonym: aortic regurgitation
has_obo_namespace: disease_ontology
id: DOID:57

rheumatic pulmonary valve disease
type: Class
subclass of: pulmonary valve disease
imported from: doid.owl
database_cross_reference: ICD9CM:397.1
database_cross_reference: SNOMEDCT_2010_1_31:18687009
database_cross_reference: SNOMEDCT_2010_1_31:194747005
database_cross_reference: SNOMEDCT_2010_1_31:266283005
database_cross_reference: UMLS_CUI:C0155579
has_exact_synonym: Rheumatic disease of pulmonary valve
has_exact_synonym: Rheumatic disease of pulmonary valve (disorder)
has_exact_synonym: Rheumatic pulmonary incompetence
has_exact_synonym: Rheumatic pulmonary valve disease NOS (disorder)
has_obo_namespace: disease_ontology
id: DOID:5748

pulmonary valve disease
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Class
    union of: Restriction
      on property: realized in
      some values from: Class
        intersection of: disease course
        intersection of: Restriction
    union of: Restriction
      on property: has material basis at all times
      some values from: pulmonary valve disorder
CVDO definition: A disease affecting the pulmonary valve of the heart.
imported from: doid.owl
database_cross_reference: ICD9CM:424.3
database_cross_reference: NCI:C78579
database_cross_reference: SNOMEDCT_2010_1_31:195001000
database_cross_reference: SNOMEDCT_2010_1_31:76267008
database_cross_reference: UMLS_CUI:C0034087
has_exact_synonym: pulmonary valve disorder
has_obo_namespace: disease_ontology
id: DOID:5749

rheumatic mitral valve incompetence
type: Class
subclass of: rheumatic disease of mitral valve
imported from: doid.owl
database_cross_reference: ICD9CM:394.1
database_cross_reference: SNOMEDCT_2010_1_31:155278007
database_cross_reference: SNOMEDCT_2010_1_31:155279004
database_cross_reference: SNOMEDCT_2010_1_31:266279005
database_cross_reference: SNOMEDCT_2010_1_31:31085000
database_cross_reference: UMLS_CUI:C0155563
has_exact_synonym: Rheumatic mitral insufficiency
has_exact_synonym: Rheumatic mitral regurgitation
has_exact_synonym: Rheumatic mitral regurgitation (disorder)
has_exact_synonym: Rheumatic mitral valve regurgitation
has_obo_namespace: disease_ontology
id: DOID:58

discrete subaortic stenosis
type: Class
subclass of: subvalvular aortic stenosis
imported from: doid.owl
database_cross_reference: MSH:D021922
database_cross_reference: UMLS_CUI:C0012628
has_obo_namespace: disease_ontology
id: DOID:5804

subvalvular aortic stenosis
type: Class
subclass of: disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: disturbed anterograd blood flow through aortic valve during left ventricular systole
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: aortic valve improper opening during left ventricular systole
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: left ventricle pathological process
CVDO editor note: This refers to a narrowing of the section of the left ventricle below the aortic valve; therefore, this was not classified as an aortic valve stenosis in CVDO.
imported from: doid.owl
database_cross_reference: MSH:D001020
database_cross_reference: NCI:C85172
database_cross_reference: UMLS_CUI:C0003500
has_obo_namespace: disease_ontology
id: DOID:5805

posteroinferior myocardial infarction
type: Class
subclass of: myocardial infarction
imported from: doid.owl
database_cross_reference: NCI:C36068
database_cross_reference: UMLS_CUI:C1142433
has_obo_namespace: disease_ontology
id: DOID:5843

myocardial infarction
type: Class
equivalent class: Class
  intersection of: infarction
  intersection of: Restriction
    on property: occurs in
    some values from: Myocardium
subclass of: Restriction
  on property: part of occurrent
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: realizes
      some values from: acute coronary syndrome
CVDO definition: An infarction occurring in the myocardium.
imported from: doid.owl
database_cross_reference: MSH:D009203
database_cross_reference: NCI:C27996
database_cross_reference: SNOMEDCT_2010_1_31:155304006
database_cross_reference: SNOMEDCT_2010_1_31:194796000
database_cross_reference: SNOMEDCT_2010_1_31:22298006
database_cross_reference: SNOMEDCT_2010_1_31:233824008
database_cross_reference: SNOMEDCT_2010_1_31:266288001
database_cross_reference: SNOMEDCT_2010_1_31:66514008
database_cross_reference: UMLS_CUI:C0027051
has_exact_synonym: Attack - heart
has_exact_synonym: MI - Myocardial infarction
has_exact_synonym: Myocardial Infarct
has_exact_synonym: Myocardial Infarctions
has_exact_synonym: Myocardial infarct
has_exact_synonym: Myocardial infarction
has_exact_synonym: Myocardial infarction (disorder)
has_exact_synonym: Myocardial infarction NOS
has_exact_synonym: heart attack
has_obo_namespace: disease_ontology
id: DOID:5844

anterolateral myocardial infarction
type: Class
subclass of: myocardial infarction
imported from: doid.owl
database_cross_reference: MSH:D056988
database_cross_reference: NCI:C35303
database_cross_reference: UMLS_CUI:C0262564
has_obo_namespace: disease_ontology
id: DOID:5845

septal myocardial infarction
type: Class
subclass of: myocardial infarction
imported from: doid.owl
database_cross_reference: NCI:C35519
database_cross_reference: UMLS_CUI:C0746727
has_obo_namespace: disease_ontology
id: DOID:5846

posterior myocardial infarction
type: Class
subclass of: myocardial infarction
imported from: doid.owl
database_cross_reference: NCI:C35399
database_cross_reference: SNOMEDCT_2010_1_31:194800006
database_cross_reference: UMLS_CUI:C0340319
has_exact_synonym: Posterior myocardial infarction NOS (disorder)
has_obo_namespace: disease_ontology
id: DOID:5847

apical myocardial infarction
type: Class
subclass of: myocardial infarction
imported from: doid.owl
database_cross_reference: NCI:C36073
database_cross_reference: UMLS_CUI:C1168331
has_obo_namespace: disease_ontology
id: DOID:5848

subendocardial myocardial infarction
type: Class
subclass of: myocardial infarction
imported from: doid.owl
database_cross_reference: NCI:C35305
database_cross_reference: UMLS_CUI:C0262568
has_obo_namespace: disease_ontology
id: DOID:5849

inferior myocardial infarction
type: Class
subclass of: myocardial infarction
imported from: doid.owl
database_cross_reference: MSH:D056989
database_cross_reference: NCI:C35398
database_cross_reference: NCI:C71070
database_cross_reference: SNOMEDCT_2010_1_31:194804002
database_cross_reference: UMLS_CUI:C0340305
has_exact_synonym: Inferior myocardial infarction NOS (disorder)
has_obo_namespace: disease_ontology
id: DOID:5850

posterolateral myocardial infarction
type: Class
subclass of: myocardial infarction
imported from: doid.owl
database_cross_reference: NCI:C35672
database_cross_reference: UMLS_CUI:C1112662
has_obo_namespace: disease_ontology
id: DOID:5851

inferolateral myocardial infarct
type: Class
subclass of: myocardial infarction
imported from: doid.owl
database_cross_reference: NCI:C35673
database_cross_reference: UMLS_CUI:C1112770
has_obo_namespace: disease_ontology
id: DOID:5852

lateral myocardial infarction
type: Class
subclass of: myocardial infarction
imported from: doid.owl
database_cross_reference: NCI:C35586
database_cross_reference: SNOMEDCT_2010_1_31:194801005
database_cross_reference: UMLS_CUI:C0340312
has_exact_synonym: Lateral myocardial infarction NOS (disorder)
has_obo_namespace: disease_ontology
id: DOID:5853

silent myocardial infarction
type: Class
subclass of: myocardial infarction
imported from: doid.owl
database_cross_reference: NCI:C35400
database_cross_reference: SNOMEDCT_2010_1_31:194796000
database_cross_reference: SNOMEDCT_2010_1_31:233843008
database_cross_reference: UMLS_CUI:C0340324
has_exact_synonym: Silent myocardial infarction
has_exact_synonym: Silent myocardial infarction (disorder)
has_obo_namespace: disease_ontology
id: DOID:5854

anteroseptal myocardial infarction
type: Class
subclass of: myocardial infarction
imported from: doid.owl
database_cross_reference: MSH:D056988
database_cross_reference: NCI:C35304
database_cross_reference: UMLS_CUI:C0262565
has_obo_namespace: disease_ontology
id: DOID:5855

occlusion precerebral artery
type: Class
subclass of: cerebrovascular disease
imported from: doid.owl
has_alternative_id: DOID:10961
has_alternative_id: DOID:1547
database_cross_reference: ICD9CM:433
database_cross_reference: ICD9CM:433.3
database_cross_reference: ICD9CM:433.9
database_cross_reference: UMLS_CUI:C0155722
database_cross_reference: UMLS_CUI:C0155725
database_cross_reference: UMLS_CUI:C0155727
has_obo_namespace: disease_ontology
has_related_synonym: Occlusion and stenosis of multiple and bilateral precerebral arteries
has_related_synonym: occlusion and stenosis of precerebral artery
id: DOID:5976

congestive heart failure
type: Class
subclass of: disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: impaired cardiac output
disjoint union of: systolic heart failure
disjoint union of: diastolic heart failure
CVDO definition: A disease characterized by the inability of the heart to pump a sufficient amount of blood throughout the body.
definition: A heart disease that is characterized by any structural or functional cardiacdisorder that impairs the ability of the heart to fill with or pump a sufficient amount ofblood throughout the body.
imported from: doid.owl
has_alternative_id: DOID:395
database_cross_reference: ICD9CM:428
database_cross_reference: ICD9CM:428.0
database_cross_reference: ICD9CM:428.9
database_cross_reference: MSH:D006333
database_cross_reference: NCI:C3080
database_cross_reference: NCI:C50577
database_cross_reference: SNOMEDCT_2010_1_31:155374007
database_cross_reference: SNOMEDCT_2010_1_31:155375008
database_cross_reference: SNOMEDCT_2010_1_31:155377000
database_cross_reference: SNOMEDCT_2010_1_31:195108009
database_cross_reference: SNOMEDCT_2010_1_31:195117009
database_cross_reference: SNOMEDCT_2010_1_31:266248006
database_cross_reference: SNOMEDCT_2010_1_31:266308000
database_cross_reference: SNOMEDCT_2010_1_31:42343007
database_cross_reference: SNOMEDCT_2010_1_31:84114007
database_cross_reference: UMLS_CUI:C0018801
database_cross_reference: UMLS_CUI:C0018802
has_exact_synonym: CHF
has_exact_synonym: Cardiac Failure Congestive
has_exact_synonym: Congestive heart disease
has_exact_synonym: Weak heart
has_obo_namespace: disease_ontology
id: DOID:6000

mitral valve disease
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Class
    union of: Restriction
      on property: realized in
      some values from: Class
        intersection of: disease course
        intersection of: Restriction
    union of: Restriction
      on property: has material basis at all times
      some values from: mitral valve disorder
CVDO definition: A disease affecting the mitral valve of the heart.
imported from: doid.owl
has_alternative_id: DOID:59
database_cross_reference: ICD9CM:424.0
database_cross_reference: NCI:C78446
database_cross_reference: SNOMEDCT_2010_1_31:11851006
database_cross_reference: SNOMEDCT_2010_1_31:194729004
database_cross_reference: SNOMEDCT_2010_1_31:194982000
database_cross_reference: UMLS_CUI:C0026265
has_exact_synonym: Mitral and aortic valve disease NOS (disorder)
has_exact_synonym: Mitral and aortic valve disease, unspecified
has_exact_synonym: disease of mitral and aortic valves
has_exact_synonym: disease of mitral and aortic valves (disorder)
has_exact_synonym: mitral valve disease
has_obo_namespace: disease_ontology
id: DOID:61

aortic valve disease
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Class
    union of: Restriction
      on property: realized in
      some values from: Class
        intersection of: disease course
        intersection of: Restriction
    union of: Restriction
      on property: has material basis at all times
      some values from: aortic valve disorder
CVDO definition: A disease affecting the aortic valve of the heart.
imported from: doid.owl
has_alternative_id: DOID:56
database_cross_reference: ICD9CM:395.9
database_cross_reference: UMLS_CUI:C0155570
has_obo_namespace: disease_ontology
id: DOID:62

genetic disease
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: has material basis at all times
    some values from: genetic disorder
subclass of: disease
definition: A disease that has_material_basis_in genetic variations in the human genome.
imported from: doid.owl
database_cross_reference: MSH:D030342
database_cross_reference: NCI:C3101
database_cross_reference: SNOMEDCT_2010_1_31:264530000
database_cross_reference: SNOMEDCT_2010_1_31:32895009
database_cross_reference: UMLS_CUI:C0019247
has_obo_namespace: disease_ontology
id: DOID:630

pulmonary valve stenosis
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: pulmonary valve narrowed opening during right ventricular systole
  intersection of: Restriction
    on property: has material basis at all times
    some values from: pulmonary valve disorder
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: disturbed anterograd blood flow through pulmonary valve during right ventricular systole
CVDO definition: A disease in which some disorder of a pulmonary valve prevents it from opening properly during right ventricular systole, occasioning disturbance in the anterograd blood flow through the valve.
imported from: doid.owl
database_cross_reference: MSH:D011666
database_cross_reference: SNOMEDCT_2010_1_31:56786000
database_cross_reference: UMLS_CUI:C0034089
has_exact_synonym: Pulmonic stenosis NOS
has_exact_synonym: Pulmonic valve stenosis (disorder)
has_exact_synonym: pulmonary stenosis NOS
has_exact_synonym: pulmonary stenosis, cause unspecified (disorder)
has_exact_synonym: pulmonary valve stenosis
has_obo_namespace: disease_ontology
id: DOID:6420

pulmonary hypertension
type: Class
subclass of: hypertension
imported from: doid.owl
database_cross_reference: MSH:D006976
database_cross_reference: NCI:C3120
database_cross_reference: SNOMEDCT_2010_1_31:155328008
database_cross_reference: SNOMEDCT_2010_1_31:266293003
database_cross_reference: SNOMEDCT_2010_1_31:70995007
database_cross_reference: UMLS_CUI:C0020542
has_exact_synonym: pulmonary hypertension
has_exact_synonym: pulmonary hypertension (disorder)
has_obo_namespace: disease_ontology
id: DOID:6432

cerebral angioma
type: Class
subclass of: brain angioma
imported from: doid.owl
database_cross_reference: NCI:C5433
database_cross_reference: UMLS_CUI:C0877388
has_exact_synonym: hemangioma of Cerebrum
has_obo_namespace: disease_ontology
id: DOID:6621

anterior spinal artery syndrome
type: Class
subclass of: spinal cord vascular disease
subclass of: cerebrovascular disease
imported from: doid.owl
database_cross_reference: MSH:D020759
database_cross_reference: SNOMEDCT_2010_1_31:2972007
database_cross_reference: UMLS_CUI:C0221069
has_exact_synonym: Anterior spinal artery occlusion syndrome (disorder)
has_obo_namespace: disease_ontology
id: DOID:6712

cerebrovascular disease
type: Class
subclass of: vascular disease - unclassified by CVDO
imported from: doid.owl
has_alternative_id: DOID:12214
has_alternative_id: DOID:8231
database_cross_reference: ICD9CM:430-438.99
database_cross_reference: ICD9CM:437.9
database_cross_reference: MSH:D002561
database_cross_reference: NCI:C2938
database_cross_reference: SNOMEDCT_2010_1_31:155388006
database_cross_reference: SNOMEDCT_2010_1_31:155412002
database_cross_reference: SNOMEDCT_2010_1_31:195249004
database_cross_reference: SNOMEDCT_2010_1_31:195595007
database_cross_reference: SNOMEDCT_2010_1_31:266312006
database_cross_reference: SNOMEDCT_2010_1_31:62914000
database_cross_reference: UMLS_CUI:C0007820
has_exact_synonym: cerebrovascular disorder
has_obo_namespace: disease_ontology
id: DOID:6713

compartment syndrome
type: Class
subclass of: ischemic disease
imported from: doid.owl
database_cross_reference: ICD9CM:958.90
database_cross_reference: MSH:D003161
database_cross_reference: SNOMEDCT_2010_1_31:111245009
database_cross_reference: SNOMEDCT_2010_1_31:212379008
database_cross_reference: SNOMEDCT_2010_1_31:45781009
database_cross_reference: UMLS_CUI:C0009492
has_exact_synonym: Compartment syndrome
has_exact_synonym: Compartment syndrome (disorder)
has_exact_synonym: Compartmental syndrome, NOS
has_obo_namespace: disease_ontology
id: DOID:682

dermatographia
type: Class
subclass of: urticaria
imported from: doid.owl
database_cross_reference: ICD9CM:708.3
database_cross_reference: SNOMEDCT_2010_1_31:123093003
database_cross_reference: SNOMEDCT_2010_1_31:156430003
database_cross_reference: SNOMEDCT_2010_1_31:201263000
database_cross_reference: SNOMEDCT_2010_1_31:201265007
database_cross_reference: SNOMEDCT_2010_1_31:238685008
database_cross_reference: SNOMEDCT_2010_1_31:247473009
database_cross_reference: SNOMEDCT_2010_1_31:270885004
database_cross_reference: SNOMEDCT_2010_1_31:402410006
database_cross_reference: SNOMEDCT_2010_1_31:402601007
database_cross_reference: SNOMEDCT_2010_1_31:7632005
database_cross_reference: UMLS_CUI:C0343065
has_exact_synonym: Dermatographic urticaria
has_exact_synonym: Dermographism
has_exact_synonym: Physical urticaria
has_obo_namespace: disease_ontology
id: DOID:743

ruptured aortic aneurysm
type: Class
subclass of: aortic aneurysm
imported from: doid.owl
database_cross_reference: ICD9CM:441.5
database_cross_reference: MSH:D001019
database_cross_reference: NCI:C27198
database_cross_reference: SNOMEDCT_2010_1_31:155423003
database_cross_reference: SNOMEDCT_2010_1_31:195264004
database_cross_reference: SNOMEDCT_2010_1_31:195615002
database_cross_reference: SNOMEDCT_2010_1_31:73067008
database_cross_reference: UMLS_CUI:C0741160
has_exact_synonym: Aortic aneurysm of unspecified site, ruptured
has_exact_synonym: Aortic aneurysm of unspecified site, ruptured (disorder)
has_exact_synonym: Ruptured Aortic Aneurysm
has_exact_synonym: Ruptured aortic aneurysm (disorder)
has_exact_synonym: Ruptured aortic aneurysm NOS
has_exact_synonym: Ruptured aortic aneurysm NOS (disorder)
has_obo_namespace: disease_ontology
id: DOID:7682
label: ruptured aortic aneurysm disease

dissecting aortic aneurysm
type: Class
subclass of: aneurysm (disease)
imported from: doid.owl
database_cross_reference: ICD9CM:441.0
database_cross_reference: NCI:C26751
database_cross_reference: SNOMEDCT_2010_1_31:155420000
database_cross_reference: SNOMEDCT_2010_1_31:308546005
database_cross_reference: SNOMEDCT_2010_1_31:67076004
database_cross_reference: UMLS_CUI:C0012736
has_obo_namespace: disease_ontology
id: DOID:7683
label: dissecting aortic aneurysm disease

ruptured abdominal aortic aneurysm
type: Class
subclass of: ruptured aortic aneurysm
imported from: doid.owl
database_cross_reference: ICD9CM:441.3
database_cross_reference: NCI:C27046
database_cross_reference: SNOMEDCT_2010_1_31:14336007
database_cross_reference: UMLS_CUI:C0265012
has_exact_synonym: Ruptured abdominal Aortic Aneurysm
has_exact_synonym: Ruptured abdominal aortic aneurysm (disorder)
has_exact_synonym: abdominal aortic aneurysm, ruptured
has_obo_namespace: disease_ontology
id: DOID:7692
label: ruptured abdominal aortic aneurysm disease

abdominal aortic aneurysm
type: Class
subclass of: aortic aneurysm
imported from: doid.owl
database_cross_reference: MSH:D017544
database_cross_reference: NCI:C27000
database_cross_reference: OMIM:100070
database_cross_reference: SNOMEDCT_2010_1_31:155422008
database_cross_reference: SNOMEDCT_2010_1_31:233985008
database_cross_reference: UMLS_CUI:C0162871
has_exact_synonym: AORTIC ANEURYSM, FAMILIAL ABDOMINAL 1
has_exact_synonym: abdominal Aortic Aneurysm
has_exact_synonym: abdominal aortic aneurysm
has_exact_synonym: abdominal aortic aneurysm (disorder)
has_obo_namespace: disease_ontology
id: DOID:7693
label: abdominal aortic aneurysm disease

ruptured thoracic aortic aneurysm
type: Class
subclass of: ruptured aortic aneurysm
imported from: doid.owl
database_cross_reference: ICD9CM:441.1
database_cross_reference: NCI:C27299
database_cross_reference: SNOMEDCT_2010_1_31:195258006
database_cross_reference: SNOMEDCT_2010_1_31:34365005
database_cross_reference: UMLS_CUI:C0265010
has_exact_synonym: Ruptured Thoracic Aneurysm
has_exact_synonym: Ruptured thoracic aortic aneurysm (disorder)
has_exact_synonym: Thoracic aortic aneurysm which has ruptured (disorder)
has_exact_synonym: Thoracic aortic aneurysm, ruptured
has_obo_namespace: disease_ontology
id: DOID:7703
label: ruptured thoracic aortic aneurysm disease

varicose veins
type: Class
subclass of: vascular disease - unclassified by CVDO
imported from: doid.owl
database_cross_reference: MSH:D014648
database_cross_reference: NCI:C35114
database_cross_reference: OMIM:192200
database_cross_reference: SNOMEDCT_2010_1_31:128060009
database_cross_reference: SNOMEDCT_2010_1_31:12856003
database_cross_reference: SNOMEDCT_2010_1_31:155468006
database_cross_reference: SNOMEDCT_2010_1_31:155482006
database_cross_reference: SNOMEDCT_2010_1_31:234053000
database_cross_reference: SNOMEDCT_2010_1_31:266331000
database_cross_reference: SNOMEDCT_2010_1_31:276504003
database_cross_reference: SNOMEDCT_2010_1_31:399989005
database_cross_reference: UMLS_CUI:C0042345
has_exact_synonym: Varix (morphologic abnormality)
has_exact_synonym: Venous ectasia
has_exact_synonym: Venous varices (disorder)
has_exact_synonym: varices
has_obo_namespace: disease_ontology
id: DOID:799
comment: OMIM mapping confirmed by DO. [LS].

carotid artery occlusion
type: Class
subclass of: occlusion precerebral artery
imported from: doid.owl
database_cross_reference: ICD9CM:433.10
database_cross_reference: UMLS_CUI:C0375275
has_exact_synonym: Occlusion and stenosis of carotid artery
has_obo_namespace: disease_ontology
id: DOID:807

interstitial myocarditis
type: Class
subclass of: myocarditis
imported from: doid.owl
database_cross_reference: NCI:C35786
database_cross_reference: SNOMEDCT_2010_1_31:37925008
database_cross_reference: UMLS_CUI:C0027060
has_exact_synonym: Interstitial myocarditis (disorder)
has_obo_namespace: disease_ontology
id: DOID:817

myocarditis
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: inflammation process in a myocardium
CVDO definition: A disease characterized by an inflammation of the myocardium.
imported from: doid.owl
database_cross_reference: ICD9CM:429.0
database_cross_reference: MSH:D009205
database_cross_reference: NCI:C34831
database_cross_reference: SNOMEDCT_2010_1_31:155380004
database_cross_reference: SNOMEDCT_2010_1_31:195119007
database_cross_reference: SNOMEDCT_2010_1_31:251060004
database_cross_reference: SNOMEDCT_2010_1_31:50920009
database_cross_reference: UMLS_CUI:C0027059
has_exact_synonym: Myocardial inflammation (finding)
has_exact_synonym: Myocarditis (disorder)
has_exact_synonym: Myocarditis NOS
has_exact_synonym: Myocarditis NOS (disorder)
has_exact_synonym: Myocarditis, unspecified
has_exact_synonym: myocarditis
has_obo_namespace: disease_ontology
id: DOID:820

rheumatic myocarditis
type: Class
subclass of: myocarditis
CVDO definition: A myocarditis caused by rheumatic fever.
imported from: doid.owl
has_alternative_id: DOID:14025
has_alternative_id: DOID:14036
database_cross_reference: ICD9CM:391.9
database_cross_reference: NCI:C34985
database_cross_reference: SNOMEDCT_2010_1_31:155270000
database_cross_reference: SNOMEDCT_2010_1_31:194713007
database_cross_reference: SNOMEDCT_2010_1_31:194750008
database_cross_reference: SNOMEDCT_2010_1_31:195136004
database_cross_reference: SNOMEDCT_2010_1_31:266285003
database_cross_reference: SNOMEDCT_2010_1_31:312591002
database_cross_reference: SNOMEDCT_2010_1_31:367538001
database_cross_reference: SNOMEDCT_2010_1_31:4536006
database_cross_reference: SNOMEDCT_2010_1_31:8805001
database_cross_reference: UMLS_CUI:C0035440
database_cross_reference: UMLS_CUI:C0489959
has_exact_synonym: Rheumatic degeneration of myocardium
has_exact_synonym: Rheumatic fever with myocarditis
has_exact_synonym: Rheumatic myocarditis
has_exact_synonym: Rheumatic myocarditis (disorder)
has_exact_synonym: Rheumatoid myocarditis (disorder)
has_exact_synonym: active rheumatic fever with myocarditis
has_exact_synonym: acute Rheumatic Myocarditis
has_exact_synonym: acute rheumatic carditis
has_exact_synonym: acute rheumatic myocarditis
has_exact_synonym: acute rheumatic myocarditis (disorder)
has_exact_synonym: acute rheumatic myocarditis (disorder) [Ambiguous]
has_obo_namespace: disease_ontology
id: DOID:8481
in_subset: gram-positive bacterial infectious disease

transient retinal arterial occlusion
type: Class
subclass of: retinal artery occlusion
imported from: doid.owl
database_cross_reference: ICD9CM:362.34
database_cross_reference: NCI:C35193
database_cross_reference: SNOMEDCT_2010_1_31:193377008
database_cross_reference: SNOMEDCT_2010_1_31:87224000
database_cross_reference: UMLS_CUI:C0154840
has_exact_synonym: Retinal transient arterial occlusion NOS (disorder)
has_exact_synonym: Transient arterial retinal occlusion (disorder)
has_exact_synonym: Transient retinal arterial occlusion
has_obo_namespace: disease_ontology
id: DOID:8482

retinal artery occlusion
type: Class
subclass of: retinal vascular occlusion
subclass of: arterial occlusive disease
imported from: doid.owl
database_cross_reference: MSH:D015356
database_cross_reference: NCI:C34978
database_cross_reference: SNOMEDCT_2010_1_31:232035005
database_cross_reference: UMLS_CUI:C0035302
has_exact_synonym: Retinal artery occlusion (disorder)
has_obo_namespace: disease_ontology
id: DOID:8483

puerperal pulmonary embolism
type: Class
subclass of: pulmonary embolism
imported from: doid.owl
database_cross_reference: ICD9CM:673
database_cross_reference: SNOMEDCT_2010_1_31:156273009
database_cross_reference: SNOMEDCT_2010_1_31:200284000
database_cross_reference: SNOMEDCT_2010_1_31:200320009
database_cross_reference: SNOMEDCT_2010_1_31:200321008
database_cross_reference: SNOMEDCT_2010_1_31:200326003
database_cross_reference: SNOMEDCT_2010_1_31:237341004
database_cross_reference: SNOMEDCT_2010_1_31:50286006
database_cross_reference: UMLS_CUI:C0157540
has_obo_namespace: disease_ontology
id: DOID:8512

acute pulmonary heart disease
type: Class
equivalent class: acute cor pulmonale
equivalent class: Class
  intersection of: cor pulmonale
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: acute disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: right ventricular myocardium dilatation
CVDO definition: A cor pulmonale that has an acute disease course during which the right ventricle becomes dilated.
CVDO editor note: 'Acute pulmonary heart disease' and 'Acute cor pulmonale' (two classes imported from DOID) are considered as equivalent in CVDO.
imported from: doid.owl
database_cross_reference: ICD9CM:415
database_cross_reference: SNOMEDCT_2010_1_31:155324005
database_cross_reference: SNOMEDCT_2010_1_31:194880009
database_cross_reference: SNOMEDCT_2010_1_31:194884000
database_cross_reference: SNOMEDCT_2010_1_31:67189007
database_cross_reference: UMLS_CUI:C0155671
has_exact_synonym: acute pulmonary heart disease (disorder)
has_exact_synonym: acute pulmonary heart disease NOS (disorder)
has_obo_namespace: disease_ontology
id: DOID:8514

cor pulmonale
type: Class
subclass of: disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Class
      union of: Restriction
        on property: has occurrent part
        some values from: right ventricular myocardium dilatation
      union of: Restriction
        on property: has occurrent part
        some values from: right ventricular myocardium hypertrophy
    intersection of: Restriction
      on property: has occurrent part
      some values from: right ventricular myocardium contraction dysfunctional process
disjoint union of: chronic pulmonary heart disease
disjoint union of: acute pulmonary heart disease
CVDO definition: A disease characterized by a dilatation or hypertrophy of the myocardium of right ventricle of the heart as a response to increased resistance or high blood pressure in the lungs, involving a failure of the right side of the heart.
CVDO editor note: Although the 1995 classification of cardiomyopathies did not include cor pulmonale, it should have included it, given the definition of cardiomyopathy it adopted.
definition: A congestive heart failure that involves a failure of the right side of the heart and is characterized by an enlargement of the right ventricle of the heart as a response to increased resistance or high blood pressure in the lungs.
imported from: doid.owl
database_cross_reference: MSH:D011660
database_cross_reference: SNOMEDCT_2010_1_31:155323004
database_cross_reference: SNOMEDCT_2010_1_31:155329000
database_cross_reference: SNOMEDCT_2010_1_31:194879006
database_cross_reference: SNOMEDCT_2010_1_31:266294009
database_cross_reference: SNOMEDCT_2010_1_31:274096000
database_cross_reference: SNOMEDCT_2010_1_31:286952009
database_cross_reference: SNOMEDCT_2010_1_31:83291003
database_cross_reference: UMLS_CUI:C0034072
has_exact_synonym: cardiopulmonary disease
has_exact_synonym: pulmonary heart disease
has_obo_namespace: disease_ontology
id: DOID:8515

pulmonary embolism and infarction
type: Class
subclass of: pathological bodily process
subclass of: Restriction
  on property: has occurrent part
  some values from: infarction
subclass of: Restriction
  on property: has occurrent part
  some values from: pulmonary embolism
CVDO definition: A pathological process consisting in a pulmonary embolism and an infarction that follows.
imported from: doid.owl
database_cross_reference: ICD9CM:415.1
database_cross_reference: UMLS_CUI:C0034066
has_obo_namespace: disease_ontology
id: DOID:8516

acute cor pulmonale
type: Class
equivalent class: Class
  intersection of: cor pulmonale
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: acute disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: right ventricular myocardium dilatation
CVDO editor note: 'Acute pulmonary heart disease' and 'Acute cor pulmonale' (two classes imported from DOID) are considered as equivalent in CVDO.
imported from: doid.owl
database_cross_reference: ICD9CM:415.0
database_cross_reference: SNOMEDCT_2010_1_31:155325006
database_cross_reference: SNOMEDCT_2010_1_31:194881008
database_cross_reference: SNOMEDCT_2010_1_31:49584005
database_cross_reference: UMLS_CUI:C0155672
has_exact_synonym: acute cor pulmonale (disorder)
has_obo_namespace: disease_ontology
id: DOID:8517

phlebitis
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: inflammation process in a vein
CVDO definition: A disease characterized by an inflammation of a vein.
imported from: doid.owl
database_cross_reference: MSH:D010689
database_cross_reference: NCI:C38003
database_cross_reference: SNOMEDCT_2010_1_31:195432009
database_cross_reference: SNOMEDCT_2010_1_31:61599003
database_cross_reference: UMLS_CUI:C0031542
has_exact_synonym: Phlebitis (disorder)
has_exact_synonym: Phlebitis NOS (disorder)
has_exact_synonym: phlebitis
has_obo_namespace: disease_ontology
id: DOID:864

vasculitis
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: inflammation process in a blood vessel
CVDO definition: A disease characterized by an inflammation of a blood vessel.
definition: A vascular disease that is an inflammatory destruction of blood vessels.
imported from: doid.owl
database_cross_reference: MSH:D014657
database_cross_reference: NCI:C26912
database_cross_reference: SNOMEDCT_2010_1_31:195375002
database_cross_reference: SNOMEDCT_2010_1_31:266325003
database_cross_reference: SNOMEDCT_2010_1_31:31996006
database_cross_reference: SNOMEDCT_2010_1_31:393589007
database_cross_reference: UMLS_CUI:C0042384
has_exact_synonym: Angiitis
has_obo_namespace: disease_ontology
id: DOID:865

vein disease
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Class
    union of: Restriction
      on property: realized in
      some values from: Class
        intersection of: disease course
        intersection of: Restriction
    union of: Restriction
      on property: has material basis at all times
      some values from: vein disorder
imported from: doid.owl
database_cross_reference: ICD9CM:453
database_cross_reference: SNOMEDCT_2010_1_31:195435006
database_cross_reference: UMLS_CUI:C0155774
has_obo_namespace: disease_ontology
id: DOID:866

vascular dementia
type: Class
subclass of: vascular disease - unclassified by CVDO
definition: A dementia that involves impairments in cognitive function caused by problems in blood vessels that feed the brain.
imported from: doid.owl
has_alternative_id: DOID:13915
database_cross_reference: MSH:D015161
database_cross_reference: NCI:C34522
database_cross_reference: SNOMEDCT_2010_1_31:154850006
database_cross_reference: SNOMEDCT_2010_1_31:191462009
database_cross_reference: SNOMEDCT_2010_1_31:192165000
database_cross_reference: SNOMEDCT_2010_1_31:192167008
database_cross_reference: SNOMEDCT_2010_1_31:192171006
database_cross_reference: SNOMEDCT_2010_1_31:268613002
database_cross_reference: SNOMEDCT_2010_1_31:429998004
database_cross_reference: SNOMEDCT_2010_1_31:56267009
database_cross_reference: UMLS_CUI:C0011263
database_cross_reference: UMLS_CUI:C0011269
has_exact_synonym: Multi Infarct Dementia
has_exact_synonym: multifocal dementia
has_obo_namespace: disease_ontology
id: DOID:8725

acute coronary syndrome
type: Class
subclass of: coronary heart disease
subclass of: Restriction
  on property: realized in
  some values from: acute disease course
CVDO definition: A coronary heart disease with an acute disease course.
CVDO editor note: DOID label 'intermediate coronary syndrome' was changed.
imported from: doid.owl
database_cross_reference: ICD9CM:411.1
database_cross_reference: MSH:D000789
database_cross_reference: NCI:C66911
database_cross_reference: SNOMEDCT_2010_1_31:155308009
database_cross_reference: SNOMEDCT_2010_1_31:155313008
database_cross_reference: SNOMEDCT_2010_1_31:155314002
database_cross_reference: SNOMEDCT_2010_1_31:194814006
database_cross_reference: SNOMEDCT_2010_1_31:194816008
database_cross_reference: SNOMEDCT_2010_1_31:194817004
database_cross_reference: SNOMEDCT_2010_1_31:194819001
database_cross_reference: SNOMEDCT_2010_1_31:233818002
database_cross_reference: SNOMEDCT_2010_1_31:233820004
database_cross_reference: SNOMEDCT_2010_1_31:25106000
database_cross_reference: SNOMEDCT_2010_1_31:4557003
database_cross_reference: SNOMEDCT_2010_1_31:59021001
database_cross_reference: SNOMEDCT_2010_1_31:64333001
database_cross_reference: UMLS_CUI:C0002965
has_exact_synonym: (Angina: [crescendo] or [unstable] or [at rest]) or (preinfarction syndrome) or (impending infarction)
has_exact_synonym: Angina at rest
has_exact_synonym: Anginal chest pain at rest
has_exact_synonym: Impending infarction (disorder)
has_exact_synonym: Preinfarction angina
has_exact_synonym: Preinfarction angina (disorder)
has_exact_synonym: Unstable angina
has_exact_synonym: Worsening angina
has_obo_namespace: disease_ontology
id: DOID:8805

subvalvular pulmonary stenosis
type: Class
subclass of: disease
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: disturbed anterograd blood flow through pulmonary valve during right ventricular systole
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: pulmonary valve narrowed opening during right ventricular systole
subclass of: Restriction
  on property: realized in
  some values from: Class
    intersection of: disease course
    intersection of: Restriction
      on property: has occurrent part
      some values from: right ventricle pathological process
CVDO editor note: DOID label 'pulmonary subvalvular stenosis' was changed for homogeneization with 'subvalvular aortic stenosis'.
imported from: doid.owl
database_cross_reference: ICD9CM:746.83
database_cross_reference: MSH:D011662
database_cross_reference: NCI:C34961
database_cross_reference: SNOMEDCT_2010_1_31:204370002
database_cross_reference: SNOMEDCT_2010_1_31:3192005
database_cross_reference: UMLS_CUI:C0034084
has_exact_synonym: Congenital Infundibular Stenosis
has_exact_synonym: Infundibular pulmonic stenosis (disorder)
has_exact_synonym: Infundibular pulmonic stenosis, congenital
has_exact_synonym: Subvalvular pulmonic stenosis
has_exact_synonym: pulmonary infundibular stenosis (disorder)
has_exact_synonym: pulmonary subvalvular stenosis
has_obo_namespace: disease_ontology
id: DOID:8861

peliosis hepatis
type: Class
subclass of: hepatic vascular disease
imported from: doid.owl
database_cross_reference: MSH:D010382
database_cross_reference: SNOMEDCT_2010_1_31:197366003
database_cross_reference: SNOMEDCT_2010_1_31:240625009
database_cross_reference: SNOMEDCT_2010_1_31:58008004
database_cross_reference: UMLS_CUI:C0030781
has_exact_synonym: hepatic peliosis (disorder)
has_obo_namespace: disease_ontology
id: DOID:914

erythromelalgia
type: Class
subclass of: peripheral vascular disease
imported from: doid.owl
database_cross_reference: ICD9CM:443.82
database_cross_reference: MSH:D004916
database_cross_reference: NCI:C34593
database_cross_reference: SNOMEDCT_2010_1_31:238777005
database_cross_reference: SNOMEDCT_2010_1_31:37151006
database_cross_reference: UMLS_CUI:C0014804
has_exact_synonym: Erythromelalgia (disorder)
has_obo_namespace: disease_ontology
id: DOID:9240

priapism
type: Class
subclass of: vascular disease - unclassified by CVDO
imported from: doid.owl
database_cross_reference: ICD9CM:607.3
database_cross_reference: MSH:D011317
database_cross_reference: NCI:C85022
database_cross_reference: SNOMEDCT_2010_1_31:155930001
database_cross_reference: SNOMEDCT_2010_1_31:198027001
database_cross_reference: SNOMEDCT_2010_1_31:4287008
database_cross_reference: SNOMEDCT_2010_1_31:6273006
database_cross_reference: UMLS_CUI:C0033117
has_exact_synonym: Mentulagra
has_exact_synonym: Priapism (disorder)
has_obo_namespace: disease_ontology
id: DOID:9286

carotid artery dissection
type: Class
subclass of: carotid artery disease
imported from: doid.owl
database_cross_reference: ICD9CM:443.21
database_cross_reference: SNOMEDCT_2010_1_31:230729006
database_cross_reference: UMLS_CUI:C0338585
has_exact_synonym: Carotid artery dissection (disorder)
has_exact_synonym: Dissection of carotid artery
has_obo_namespace: disease_ontology
id: DOID:9348

strictly posterior acute myocardial infarction
type: Class
subclass of: acute myocardial infarction
imported from: doid.owl
database_cross_reference: ICD9CM:410.60
database_cross_reference: UMLS_CUI:C0155652
has_obo_namespace: disease_ontology
id: DOID:9407

acute myocardial infarction
type: Class
subclass of: myocardial infarction
imported from: doid.owl
database_cross_reference: ICD9CM:410
database_cross_reference: ICD9CM:410.9
database_cross_reference: ICD9CM:410.90
database_cross_reference: NCI:C35204
database_cross_reference: SNOMEDCT_2010_1_31:155304006
database_cross_reference: SNOMEDCT_2010_1_31:194796000
database_cross_reference: SNOMEDCT_2010_1_31:194811003
database_cross_reference: SNOMEDCT_2010_1_31:266288001
database_cross_reference: SNOMEDCT_2010_1_31:57054005
database_cross_reference: UMLS_CUI:C0155626
has_obo_namespace: disease_ontology
id: DOID:9408

intracranial hypertension
type: Class
subclass of: hypertension
imported from: doid.owl
database_cross_reference: MSH:D019586
database_cross_reference: NCI:C84791
database_cross_reference: SNOMEDCT_2010_1_31:155052007
database_cross_reference: SNOMEDCT_2010_1_31:267701004
database_cross_reference: SNOMEDCT_2010_1_31:271719001
database_cross_reference: SNOMEDCT_2010_1_31:28073009
database_cross_reference: UMLS_CUI:C0151740
has_exact_synonym: Raised intracranial pressure
has_obo_namespace: disease_ontology
id: DOID:9428

pulmonary embolism
type: Class
equivalent class: Class
  intersection of: embolism
  intersection of: Restriction
    on property: occurs in
    some values from: Pulmonary artery
CVDO definition: An embolism that occurs in a pulmonary artery.
imported from: doid.owl
database_cross_reference: MSH:D011655
database_cross_reference: NCI:C50713
database_cross_reference: SNOMEDCT_2010_1_31:155326007
database_cross_reference: SNOMEDCT_2010_1_31:194882001
database_cross_reference: SNOMEDCT_2010_1_31:266292008
database_cross_reference: SNOMEDCT_2010_1_31:59282003
database_cross_reference: UMLS_CUI:C0034065
has_exact_synonym: pulmonary artery embolism
has_obo_namespace: disease_ontology
id: DOID:9477

vascular skin disease
type: Class
subclass of: vascular disease - unclassified by CVDO
imported from: doid.owl
database_cross_reference: ICD9CM:709.1
database_cross_reference: MSH:D017445
database_cross_reference: NCI:C35254
database_cross_reference: SNOMEDCT_2010_1_31:11263005
database_cross_reference: SNOMEDCT_2010_1_31:201306008
database_cross_reference: SNOMEDCT_2010_1_31:267820009
database_cross_reference: UMLS_CUI:C0162819
has_obo_namespace: disease_ontology
id: DOID:9540

systolic heart failure
type: Class
subclass of: congestive heart failure
CVDO definition: A congestive heart failure with impaired ejection fraction.
imported from: doid.owl
database_cross_reference: ICD9CM:428.2
database_cross_reference: ICD9CM:428.20
database_cross_reference: MSH:D054143
database_cross_reference: SNOMEDCT_2010_1_31:417996009
database_cross_reference: UMLS_CUI:C1135191
has_obo_namespace: disease_ontology
id: DOID:9651

toxic myocarditis
type: Class
subclass of: acute myocarditis
imported from: doid.owl
database_cross_reference: ICD9CM:422.93
database_cross_reference: SNOMEDCT_2010_1_31:31993003
database_cross_reference: UMLS_CUI:C0155691
has_obo_namespace: disease_ontology
id: DOID:9694

pelvic varices
type: Class
subclass of: varicose veins
imported from: doid.owl
database_cross_reference: ICD9CM:456.5
database_cross_reference: SNOMEDCT_2010_1_31:17406005
database_cross_reference: SNOMEDCT_2010_1_31:195481006
database_cross_reference: SNOMEDCT_2010_1_31:266271008
database_cross_reference: UMLS_CUI:C0155795
has_obo_namespace: disease_ontology
id: DOID:9742

perianal hematoma
type: Class
subclass of: hemorrhoid
imported from: doid.owl
database_cross_reference: ICD9CM:455.4
database_cross_reference: SNOMEDCT_2010_1_31:155474006
database_cross_reference: SNOMEDCT_2010_1_31:157525008
database_cross_reference: SNOMEDCT_2010_1_31:211490002
database_cross_reference: SNOMEDCT_2010_1_31:26373009
database_cross_reference: SNOMEDCT_2010_1_31:269372002
database_cross_reference: UMLS_CUI:C0155784
has_exact_synonym: External thrombosed haemorrhoids
has_exact_synonym: Thrombosed external hemorrhoids
has_obo_namespace: disease_ontology
id: DOID:9745

hemorrhoid
type: Class
subclass of: pelvic varices
imported from: doid.owl
database_cross_reference: ICD9CM:455
database_cross_reference: MSH:D006484
database_cross_reference: NCI:C26792
database_cross_reference: SNOMEDCT_2010_1_31:155469003
database_cross_reference: SNOMEDCT_2010_1_31:155477004
database_cross_reference: SNOMEDCT_2010_1_31:195472000
database_cross_reference: SNOMEDCT_2010_1_31:70153002
database_cross_reference: UMLS_CUI:C0019112
has_obo_namespace: disease_ontology
id: DOID:9746

internal hemorrhoid
type: Class
subclass of: hemorrhoid
imported from: doid.owl
database_cross_reference: ICD9CM:455.6
database_cross_reference: SNOMEDCT_2010_1_31:82985000
database_cross_reference: UMLS_CUI:C0041844
has_obo_namespace: disease_ontology
id: DOID:9749

myocardial stunning
type: Class
subclass of: myocardial infarction
imported from: doid.owl
database_cross_reference: MSH:D017682
database_cross_reference: UMLS_CUI:C0206146
has_obo_namespace: disease_ontology
id: DOID:9767

heart aneurysm
type: Class
subclass of: disorder
subclass of: Restriction
  on property: located in at all times
  some values from: Heart
imported from: doid.owl
database_cross_reference: MSH:D006322
database_cross_reference: SNOMEDCT_2010_1_31:155317009
database_cross_reference: SNOMEDCT_2010_1_31:194847002
database_cross_reference: SNOMEDCT_2010_1_31:65340007
database_cross_reference: UMLS_CUI:C0018789
has_exact_synonym: cardiac aneurysm
has_obo_namespace: disease_ontology
id: DOID:9768

diastolic heart failure
type: Class
subclass of: congestive heart failure
CVDO definition: A congestive heart failure with preserved ejection fraction.
imported from: doid.owl
database_cross_reference: ICD9CM:428.3
database_cross_reference: ICD9CM:428.30
database_cross_reference: MSH:D054144
database_cross_reference: SNOMEDCT_2010_1_31:418304008
database_cross_reference: UMLS_CUI:C1135196
has_obo_namespace: disease_ontology
id: DOID:9775

polyarteritis nodosa
type: Class
subclass of: vascular skin disease
imported from: doid.owl
database_cross_reference: ICD9CM:446.0
database_cross_reference: MSH:D010488
database_cross_reference: NCI:C26847
database_cross_reference: SNOMEDCT_2010_1_31:155441006
database_cross_reference: SNOMEDCT_2010_1_31:155445002
database_cross_reference: SNOMEDCT_2010_1_31:195347004
database_cross_reference: SNOMEDCT_2010_1_31:266323005
database_cross_reference: SNOMEDCT_2010_1_31:286960005
database_cross_reference: SNOMEDCT_2010_1_31:66121003
database_cross_reference: UMLS_CUI:C0031036
has_obo_namespace: disease_ontology
id: DOID:9810

mitral valve prolapse
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: mitral valve leaflet displacement into the left atrium during left ventricular systole
  intersection of: Restriction
    on property: has material basis at all times
    some values from: degenerated structure in a mitral valve leaflet
CVDO definition: A disease characterized by the displacement of a degenerated mitral valve leaflet into the left atrium during systole.
imported from: doid.owl
database_cross_reference: MSH:D008945
database_cross_reference: NCI:C50655
database_cross_reference: OMIM:157700
database_cross_reference: SNOMEDCT_2010_1_31:155386005
database_cross_reference: SNOMEDCT_2010_1_31:194977007
database_cross_reference: SNOMEDCT_2010_1_31:194980008
database_cross_reference: SNOMEDCT_2010_1_31:409712001
database_cross_reference: SNOMEDCT_2010_1_31:42069006
database_cross_reference: SNOMEDCT_2010_1_31:45023003
database_cross_reference: SNOMEDCT_2010_1_31:8074002
database_cross_reference: UMLS_CUI:C0026267
has_exact_synonym: BARLOWS SYNDROME
has_exact_synonym: Floppy mitral valve
has_obo_namespace: disease_ontology
id: DOID:988
comment: OMIM mapping confirmed by DO. [SN].

heart valve prolapse
type: Class
equivalent class: Class
  intersection of: disease
  intersection of: Restriction
    on property: realized in
    some values from: Class
      intersection of: disease course
      intersection of: Restriction
        on property: has occurrent part
        some values from: heart valve leaflet displacement into a cardiac chamber
  intersection of: Restriction
    on property: has material basis at all times
    some values from: degenerated structure in a heart valve leaflet
CVDO definition: A disease characterized by the displacement of a degenerated heart valve leaflet during systole.
imported from: doid.owl
database_cross_reference: MSH:D016127
database_cross_reference: SNOMEDCT_2010_1_31:398995000
database_cross_reference: UMLS_CUI:C0079485
has_exact_synonym: Cardiac valve prolapse
has_obo_namespace: disease_ontology
id: DOID:989

Marable's syndrome
type: Class
subclass of: compression disease
imported from: doid.owl
database_cross_reference: ICD9CM:447.4
database_cross_reference: SNOMEDCT_2010_1_31:9250002
database_cross_reference: UMLS_CUI:C0152098
has_exact_synonym: Celiac artery compression syndrome
has_obo_namespace: disease_ontology
id: DOID:9892

peripartum cardiomyopathy
type: Class
subclass of: dilated cardiomyopathy
CVDO definition: A dilated cardiomyopathy resulting from a pregnancy. It presents typically between the last month of pregnancy and up to six months postpartum.
imported from: doid.owl
has_alternative_id: DOID:11697
has_alternative_id: DOID:11980
database_cross_reference: ICD9CM:674.5
database_cross_reference: UMLS_CUI:C0877208
has_exact_synonym: antepartum peripartum cardiomyopathy
has_exact_synonym: postpartum peripartum cardiomyopathy
has_obo_namespace: disease_ontology
id: DOID:9997

Myocardium of ventricle
type: Class
subclass of: Region of myocardium
subclass of: Restriction
  on property: located in at all times
  some values from: Cardiac ventricle
imported from: fma.owl
has_exact_synonym: Ventricular myocardium
has_obo_namespace: fma
id: FMA:12151

Wall of cardiac chamber
type: Class
subclass of: Region of wall of heart
subclass of: Restriction
  on property: located in at all times
  some values from: Cardiac chamber
definition: Region of wall of heart which consists of endocardium, myocardium and epicardium that surrounds the cavity of a cardiac chamber.
imported from: fma.owl
has_exact_synonym: Cardiac chamber wall
has_obo_namespace: fma
id: FMA:13256

Organ component
type: Class
subclass of: Cardinal organ part
definition: Cardinal organ part which is bounded predominantly by bonafide boundaries. Examples: lobe of lung, osteon, acinus, submucosa, anterior leaflet of mitral valve, capsule of kidney, cortical bone, muscle fasciculus.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:14065

Cardiac muscle tissue
type: Class
subclass of: Striated muscle tissue
definition: Tissue which consists of cardiac myocytes surrounded by cardiac endomysium. Examples: Cardiac muscle tissue proper, conducting tissue of heart.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:14068

Venous tree organ
type: Class
subclass of: Vascular tree
definition: Vascular tree, the organ parts of which are veins. Examples: There are only three canonical instances, systemic venous tree (organ), pulmonary venous tree (organ) and portal venous tree (organ).
imported from: fma.owl
has_obo_namespace: fma
id: FMA:14284

Common iliac vein
type: Class
subclass of: Subdivision of inferior vena caval tree
imported from: fma.owl
has_exact_synonym: Common iliac venous tree
has_obo_namespace: fma
id: FMA:14333

External iliac vein
type: Class
subclass of: Subdivision of inferior vena caval tree
imported from: fma.owl
has_obo_namespace: fma
id: FMA:18883

Internal iliac vein
type: Class
subclass of: Subdivision of inferior vena caval tree
imported from: fma.owl
has_obo_namespace: fma
id: FMA:18884

Femoral vein
type: Class
subclass of: Subdivision of external iliac vein
imported from: fma.owl
has_obo_namespace: fma
id: FMA:21185

Arterial trunk
type: Class
subclass of: Segment of arterial tree organ
definition: Tubular organ part, the wall and lumen of which are continuous with those of the ventricles of the heart, directly or indirectly through branches of the aorta and pulmonary trunk. Examples: bronchial artery, hepatic artery, coronary artery, truncus anterior of right pulmonary artery, aorta.
imported from: fma.owl
has_exact_synonym: Trunk of artery
has_obo_namespace: fma
id: FMA:30313

Organ cluster
type: Class
subclass of: Anatomical cluster
definition: Anatomical cluster which consists of all or some members of one or more organ subclasses which are grouped together according to some shared attributes. Examples: abdominal viscera, pelvic viscera.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:32406

Vascular tree
type: Class
subclass of: Hollow tree organ
subclass of: Restriction
  on property: located in at all times
  some values from: Cardiovascular system
definition: Hollow tree, the organ parts of which are arteries, veins or lymphatic vessels. Examples: systemic arterial tree (organ), portal venous tree (organ), thoracic duct tree.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:3710

Aorta
type: Class
subclass of: Systemic arterial trunk
imported from: fma.owl
has_exact_synonym: Trunk of aortic tree
has_exact_synonym: Trunk of systemic arterial tree
has_obo_namespace: fma
id: FMA:3734

Common carotid artery
type: Class
subclass of: Systemic artery
imported from: fma.owl
has_exact_synonym: Carotid artery
has_exact_synonym: Trunk of common carotid tree
has_obo_namespace: fma
id: FMA:3939

Muscle layer
type: Class
subclass of: Organ component layer
imported from: fma.owl
has_exact_synonym: Muscularis layer
has_obo_namespace: fma
id: FMA:45634

Arterial tree organ
type: Class
subclass of: Vascular tree
definition: Vascular tree, the organ parts of which are arteries. Examples: There are only two canonical instances, systemic arterial tree (organ) and pulmonary arterial tree (organ).
imported from: fma.owl
has_obo_namespace: fma
id: FMA:45840

Anatomical cluster
type: Class
subclass of: Anatomical structure
definition: Anatomical structure, which has as its parts a heterogeneous collection of organs, organ parts, cells, cell parts or body part subdivisions that are adjacent to, or continuous with one another; does not constitute a cell part, cell, tissue, organ, organ system or organ system subdivision, cardinal body part, body part subdivision or anatomical junction. Examples: joint, adnexa of uterus, root of lung, renal pedicle, back.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:49443

Branch of ophthalmic artery
type: Class
subclass of: Subdivision of cerebral part of internal carotid artery
imported from: fma.owl
has_exact_synonym: Ophthalmic arterial branch
has_obo_namespace: fma
id: FMA:49872

Central retinal artery
type: Class
subclass of: Branch of ophthalmic artery
imported from: fma.owl
has_exact_synonym: Central artery of retina
has_exact_synonym: Retinal artery
has_exact_synonym: Zinn's artery
has_obo_namespace: fma
id: FMA:49879

Coronary artery
type: Class
subclass of: Systemic artery
definition: Systemic artery which supplies the heart.
imported from: fma.owl
has_exact_synonym: Coronary arterial tree
has_obo_namespace: fma
id: FMA:49893

Systemic arterial trunk
type: Class
subclass of: Arterial trunk
imported from: fma.owl
has_obo_namespace: fma
id: FMA:49918

Artery
type: Class
subclass of: Segment of arterial tree organ
definition: Subdivision of arterial tree (organ) which consists of branching sets of tubes (arterial trunk) that form a tree; together with other arterial trees (organ part), it constitutes an arterial tree (organ). Examples: pulmonary arterial tree, right coronary arterial tree, superior mesenteric tree.
imported from: fma.owl
has_exact_synonym: Arterial subtree
has_exact_synonym: Arterial tree organ part
has_exact_synonym: Arterial vessel
has_obo_namespace: fma
id: FMA:50720

Region of vascular tree organ
type: Class
subclass of: Region of organ component
subclass of: Restriction
  on property: located in at all times
  some values from: Vascular tree
imported from: fma.owl
has_exact_synonym: Vascular tree organ region
has_obo_namespace: fma
id: FMA:50722

Vein
type: Class
subclass of: Segment of venous tree organ
definition: Subdivision of venous tree (organ) which consists of branching sets of tubes (venous trunks) that form a tree; together with other venous trees (organ part), it constitutes a venous tree (organ). Examples: subclavian venous tree, jugular tree, extrahepatic portal tree, common iliac venous tree.
imported from: fma.owl
has_exact_synonym: Venous subtree
has_exact_synonym: Venous tree organ part
has_exact_synonym: Venous vessel
has_obo_namespace: fma
id: FMA:50723

Dural venous sinus
type: Class
subclass of: Subdivision of brachiocephalic vein
imported from: fma.owl
has_exact_synonym: Cranial dural venous sinus
has_exact_synonym: Dural sinus
has_obo_namespace: fma
id: FMA:50762

Transverse sinus
type: Class
subclass of: Paired dural venous sinus
imported from: fma.owl
has_exact_synonym: Lateral sinus
has_obo_namespace: fma
id: FMA:50763

Cavernous sinus
type: Class
subclass of: Paired dural venous sinus
imported from: fma.owl
has_obo_namespace: fma
id: FMA:50772

Brain
type: Class
subclass of: Organ component of neuraxis
definition: Segment of neuraxis that has as its parts gray matter and white matter that surround the cerebral ventricular system; Examples: There is only one brain.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:50801

Paired dural venous sinus
type: Class
subclass of: Dural venous sinus
imported from: fma.owl
has_obo_namespace: fma
id: FMA:52568

Tunica intima
type: Class
subclass of: Organ component layer
definition: Organ component layer which consists of the endothelium and the fibroelastic connective tissue.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:55589

Cavitated organ
type: Class
subclass of: Organ
definition: Organ the unshared parts of which surround one or more macroscopic anatomical spaces. Examples: neuraxis, tooth, esophagus, heart, long bone, corpus spongiosum of penis.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:55671

Organ with organ cavity
type: Class
subclass of: Cavitated organ
definition: Cavitated organ in which its unshared parts surround one continuous anatomical space. Examples: stomach, urinary bladder, esophagus, uterine tube.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:55672

Organ with cavitated organ parts
type: Class
subclass of: Cavitated organ
definition: Cavitated organ in which its unshared parts surround two or more macroscopic anatomical spaces. Examples: heart, long bone, corpus spongiosum of penis, bulb of vestibule.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:55673

Hollow tree organ
type: Class
subclass of: Organ with organ cavity
definition: Organ with organ cavity, which consists of an arborizing set of tubular organ parts, the walls of which are continuous and surround a continuous lumen. Examples: systemic arterial tree (organ), tracheobronchial tree, biliary tree.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:55677

Subdivision of conducting system of heart
type: Class
subclass of: Conducting tissue of heart
imported from: fma.owl
has_obo_namespace: fma
id: FMA:6266

Capillary
type: Class
subclass of: Region of vascular tree organ
definition: Subdivision of vascular tree (organ) which connects an arteriole to a venule or vice-versa.
imported from: fma.owl
has_exact_synonym: Blood capillary
has_exact_synonym: Capillary vessel
has_obo_namespace: fma
id: FMA:63194

Pulmonary artery
type: Class
subclass of: Artery
imported from: fma.owl
has_exact_synonym: Pulmonary arterial tree
has_exact_synonym: Pulmonary arterial tree organ part
has_obo_namespace: fma
id: FMA:66326

Systemic artery
type: Class
subclass of: Artery
imported from: fma.owl
has_exact_synonym: Systemic arterial subtree
has_obo_namespace: fma
id: FMA:66464

Systemic vein
type: Class
subclass of: Vein
imported from: fma.owl
has_exact_synonym: Systemic venous tree organ part
has_obo_namespace: fma
id: FMA:66644

Portal vein
type: Class
subclass of: Vein
imported from: fma.owl
has_exact_synonym: Portal venous tree organ part
has_obo_namespace: fma
id: FMA:66645

Anatomical structure
type: Class
subclass of: Material anatomical entity
definition: Material anatomical entity which is generated by coordinated expression of the organism's own genes that guide its morphogenesis; has inherent 3D shape; its parts are connected and spatially related to one another in patterns determined by coordinated gene expression. Examples: heart, right ventricle, mitral valve, myocardium, endothelium, lymphocyte, fibroblast, thorax, cardiovascular system, hemoglobin, T cell receptor.
imported from: fma.owl
has_exact_synonym: Biological structure
has_obo_namespace: fma
id: FMA:67135

Material anatomical entity
type: Class
subclass of: material entity
CVDO editor note: This class was relocated as a son of BFO 'Material entity', and BFO 2.0 'located in at all times' relations were added between relevant FMA classes; they should ultimately be replaced by a genuine version of FMA using BFO 2.0 relations.
definition: Physical anatomical entity which has mass. Examples: hemoglobin molecule, mitochondrion, hepatocyte, erythrocyte, heart, head, blood, urine.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:67165

Organ
type: Class
subclass of: Anatomical structure
definition: Anatomical structure which has as its direct parts portions of two or more types of tissue or two or more types of cardinal organ part which constitute a maximally connected anatomical structure demarcated predominantly by a bona fide anatomical surface. Examples: femur, biceps, liver, heart, skin, tracheobronchial tree, ovary.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:67498

Anatomical valve
type: Class
subclass of: Organ component
imported from: fma.owl
has_obo_namespace: fma
id: FMA:67611

Organ region
type: Class
subclass of: Cardinal organ part
definition: Cardinal organ part which is a fiat subdivision of an organ. Examples: lingula of left lung, tail of pancreas, artery, trochanter, nodulus of semilunar valve, right side of heart, duodenum, fundus of stomach.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:67619

Striated muscle tissue
type: Class
subclass of: Portion of muscle tissue
definition: Tissue which consists of striated muscle fibers surrounded by endomysium. Examples: Skeletal muscle tissue, Cardiac muscle tissue.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:67905

Subdivision of common carotid artery
type: Class
subclass of: Systemic artery
imported from: fma.owl
has_exact_synonym: Common carotid arterial subdivision
has_obo_namespace: fma
id: FMA:70504

Subdivision of internal carotid artery
type: Class
subclass of: Subdivision of common carotid artery
imported from: fma.owl
has_exact_synonym: Branch of internal carotid artery
has_exact_synonym: Internal carotid arterial subdivision
has_obo_namespace: fma
id: FMA:70506

Subdivision of cerebral part of internal carotid artery
type: Class
subclass of: Subdivision of internal carotid artery
imported from: fma.owl
has_obo_namespace: fma
id: FMA:70523

Heart
type: Class
subclass of: Organ with cavitated organ parts
subclass of: Restriction
  on property: located in at all times
  some values from: Cardiovascular system
imported from: fma.owl
has_obo_namespace: fma
id: FMA:7088

Cardiac chamber
type: Class
subclass of: Organ chamber
subclass of: Restriction
  on property: located in at all times
  some values from: Heart
definition: Organ chamber which consists of a wall that surrounds the cavity of a cardiac atrium or ventricle.
imported from: fma.owl
has_exact_synonym: Chamber of heart
has_obo_namespace: fma
id: FMA:7095

Right atrium
type: Class
subclass of: Cardiac atrium
definition: Right cardiac chamber which is continuous with the superior vena cava and inferior vena cava.
imported from: fma.owl
has_exact_synonym: Right atrium of heart
has_obo_namespace: fma
id: FMA:7096

Left atrium
type: Class
subclass of: Cardiac atrium
definition: Left cardiac chamber which is continuous with the pulmonary venous trunk.
imported from: fma.owl
has_exact_synonym: Left atrium of heart
has_obo_namespace: fma
id: FMA:7097

Right ventricle
type: Class
subclass of: Cardiac ventricle
definition: Right cardiac chamber which is continuous with the pulmonary arterial trunk.
imported from: fma.owl
has_exact_synonym: Right ventricle of heart
has_obo_namespace: fma
id: FMA:7098

Cardiac atrium
type: Class
subclass of: Cardiac chamber
definition: Cardiac chamber which consists of a wall that surrounds the cavity of an atrium.
imported from: fma.owl
has_exact_synonym: Atrium of heart
has_obo_namespace: fma
id: FMA:7099

Cardiac ventricle
type: Class
subclass of: Cardiac chamber
definition: Cardiac chamber which consists of a wall that surrounds the cavity of a ventricle.
imported from: fma.owl
has_exact_synonym: Lower chamber of heart
has_exact_synonym: Ventricle of heart
has_obo_namespace: fma
id: FMA:7100

Left ventricle
type: Class
subclass of: Cardiac ventricle
definition: Left cardiac chamber which is continuous with the aorta.
imported from: fma.owl
has_exact_synonym: Left ventricle of heart
has_obo_namespace: fma
id: FMA:7101

Cardiac valve
type: Class
subclass of: Anatomical valve
subclass of: Restriction
  on property: located in at all times
  some values from: Heart
definition: Anatomical valve which has as its parts the endocardium and fibroelastic connective tissue attached to the fibrous ring of heart.
imported from: fma.owl
has_exact_synonym: Heart valve
has_exact_synonym: Valve of heart
has_obo_namespace: fma
id: FMA:7110

Organ system
type: Class
subclass of: Anatomical structure
definition: Anatomical structure, which has as its direct parts instances of one or more organ types which are interconnected with one another by zones of continuity. Examples: skeletal system, cardiovascular system, alimentary system.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:7149

Cardiovascular system
type: Class
subclass of: Organ system
definition: Organ system which consists of the heart, the systemic and pulmonary arterial and venous system, the lymphatic and the portal venous system.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:7161

Atrioventricular valve
type: Class
subclass of: Cardiac valve
definition: Cardiac valve which has as its parts the leaf of cardiac valve that separates the atrium from the ventricle.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:7233

Tricuspid valve
type: Class
subclass of: Atrioventricular valve
definition: Atrioventricular valve which has as its parts the anterior, posterior and septal leaflets, attached to the fibrous ring of tricuspid valve.
imported from: fma.owl
has_exact_synonym: Right atrioventricular valve
has_obo_namespace: fma
id: FMA:7234

Mitral valve
type: Class
subclass of: Atrioventricular valve
definition: Atrioventricular valve which has as its parts the anterior and posterior leaflets, attached to the fibrous ring of mitral valve.
imported from: fma.owl
has_exact_synonym: Bicuspid valve
has_exact_synonym: Left atrioventricular valve
has_obo_namespace: fma
id: FMA:7235

Aortic valve
type: Class
subclass of: Cardiac valve
definition: Cardiac valve which has as its parts the anterior, right posterior and left posterior cusps, attached to the fibrous ring of aortic valve.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:7236

Pulmonary valve
type: Class
subclass of: Cardiac valve
definition: Cardiac valve which has as its parts the right anterior, left anterior and posterior cusps, attached to the fibrous ring of pulmonary valve.
imported from: fma.owl
has_exact_synonym: Pulmonic valve
has_obo_namespace: fma
id: FMA:7246

Endocardium
type: Class
subclass of: Tunica intima
subclass of: Restriction
  on property: located in at all times
  some values from: Heart
definition: Tunica intima which has as its parts the endothelium of endocardium and the fibroelastic connective tissue that surrounds the cavity of a cardiac chamber.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:7280

Subdivision of brachiocephalic vein
type: Class
subclass of: Subdivision of superior vena caval tree
imported from: fma.owl
has_exact_synonym: Brachiocephalic venous subdivision
has_exact_synonym: Tributary of brachiocephalic vein
has_obo_namespace: fma
id: FMA:77883

Subdivision of superior vena caval tree
type: Class
subclass of: Systemic vein
imported from: fma.owl
has_exact_synonym: Superior vena caval tree subdivision
has_obo_namespace: fma
id: FMA:78048

Subdivision of inferior vena caval tree
type: Class
subclass of: Systemic vein
imported from: fma.owl
has_exact_synonym: Inferior vena caval tree subdivision
has_obo_namespace: fma
id: FMA:78049

Subdivision of external iliac vein
type: Class
subclass of: Subdivision of inferior vena caval tree
imported from: fma.owl
has_exact_synonym: External iliac venous subdivision
has_obo_namespace: fma
id: FMA:78204

Cardinal organ part
type: Class
subclass of: Anatomical structure
definition: anatomical structure which has as its direct parts two or more types of tissue and is continuous with one or more anatomical structures likewise constituted by two or more portions of tissues distinct from those of their complement. Examples: osteon, cortical bone, neck of femur, bronchopulmonary segment, left lobe of liver, anterior right side of heart, interventricular branch of left coronary artery, right atrium, mitral valve, head of pancreas.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:82472

Organ chamber
type: Class
subclass of: Organ component
imported from: fma.owl
has_obo_namespace: fma
id: FMA:82481

Organ component layer
type: Class
subclass of: Organ component
imported from: fma.owl
has_obo_namespace: fma
id: FMA:82485

Organ component of neuraxis
type: Class
subclass of: Organ component
definition: Organ component which is part of the brain or spinal cord.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:83153

Conducting tissue of heart
type: Class
subclass of: Cardiac muscle tissue
subclass of: Restriction
  on property: located in at all times
  some values from: Heart
imported from: fma.owl
has_exact_synonym: Specialized conducting tissue of heart
has_exact_synonym: Specialized muscle tissue of heart
has_obo_namespace: fma
id: FMA:83378

Muscle layer of organ
type: Class
subclass of: Muscle layer
imported from: fma.owl
has_obo_namespace: fma
id: FMA:85353

Region of myocardium
type: Class
subclass of: Region of organ component
subclass of: Restriction
  on property: located in at all times
  some values from: Myocardium
imported from: fma.owl
has_exact_synonym: Myocardial zone
has_exact_synonym: Myocardium region
has_exact_synonym: Zone of myocardium
has_obo_namespace: fma
id: FMA:86044

Region of organ component
type: Class
subclass of: Cardinal organ part
definition: Cardinal organ part which is a fiat subdivision of an organ component. Examples: cervical part of wall of esophagus, mucosa of body of stomach.
imported from: fma.owl
has_exact_synonym: Organ component region
has_obo_namespace: fma
id: FMA:86103

Organ segment
type: Class
subclass of: Organ region
definition: Organ region with one or more anchored fiat boundaries. Examples: artery, trunk of nerve, cervical part of esophagus, pelvic part of vagina, horn of thyroid cartilage, anterior segment of eyeball.
imported from: fma.owl
has_exact_synonym: Organ region with fixed fiat boundary
has_exact_synonym: Segment of organ
has_obo_namespace: fma
id: FMA:86140

Segment of arterial tree organ
type: Class
subclass of: Organ segment
subclass of: Restriction
  on property: located in at all times
  some values from: Arterial tree organ
imported from: fma.owl
has_exact_synonym: Arterial tree organ segment
has_obo_namespace: fma
id: FMA:86187

Segment of venous tree organ
type: Class
subclass of: Organ segment
subclass of: Restriction
  on property: located in at all times
  some values from: Venous tree organ
imported from: fma.owl
has_exact_synonym: Venous tree organ segment
has_obo_namespace: fma
id: FMA:86188

Region of wall of heart
type: Class
subclass of: Region of organ component
imported from: fma.owl
has_obo_namespace: fma
id: FMA:86212

Myocardium
type: Class
subclass of: Muscle layer of organ
subclass of: Restriction
  on property: located in at all times
  some values from: Heart
definition: Muscle layer of organ which has as its parts the myocardium proper and the conducting system of the heart.
imported from: fma.owl
has_exact_synonym: Heart muscle
has_exact_synonym: Muscle of heart
has_obo_namespace: fma
id: FMA:9462

Myocardium of right ventricle
type: Class
subclass of: Myocardium of ventricle
subclass of: Restriction
  on property: located in at all times
  some values from: Right ventricle
definition: Myocardium of ventricle which is continuous with the tunica media of the pulmonary trunk.
imported from: fma.owl
has_exact_synonym: Right ventricular myocardium
has_obo_namespace: fma
id: FMA:9535

Myocardium of left ventricle
type: Class
subclass of: Myocardium of ventricle
subclass of: Restriction
  on property: located in at all times
  some values from: Left ventricle
definition: Myocardium of ventricle which is continuous with the tunica media of aorta.
imported from: fma.owl
has_exact_synonym: Left ventricular myocardium
has_obo_namespace: fma
id: FMA:9558

Portion of tissue
type: Class
subclass of: Anatomical structure
definition: Anatomical structure which has as its parts cells of predominantly one type with or without intercellular matrix. Examples: epithelium, muscle tissue, connective tissue, neural tissue, lymphoid tissue.
imported from: fma.owl
has_exact_synonym: Tissue
has_obo_namespace: fma
id: FMA:9637

Portion of muscle tissue
type: Class
subclass of: Portion of tissue
definition: Tissue which consists of muscle cells surrounded by a reticulum of collagen fibers or fine connective tissue [endomysium]. Examples: Smooth muscle, Cardiac muscle.
imported from: fma.owl
has_exact_synonym: Muscle tissue
has_obo_namespace: fma
id: FMA:9641

Serous sac
type: Class
subclass of: Organ with organ cavity
definition: Organ with organ cavity, which has as parts a serous membrane and a serous cavity . Examples: pleural sac, pericardial sac, tendon sheath, bursa.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:9689

Pericardial sac
type: Class
subclass of: Serous sac
definition: Serous sac, which has as parts the serous pericardium and the pericardial cavity . Examples: There is only one pericardial sac.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:9868

Pericardium
type: Class
subclass of: Organ cluster
subclass of: Restriction
  on property: located in at all times
  some values from: Cardiovascular system
definition: Organ cluster which has as its parts the fibrous pericardium and the pericardial sac.
imported from: fma.owl
has_obo_namespace: fma
id: FMA:9869

disease
type: Class
subclass of: disposition
CVDO definition: In order to obtain the taxonomy of diseases / disorders / pathological process in CVDO, it is necessary to use the reasoner first and to look at the inferred class hierarchy.
definition: A disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism.
definition editor: Albert Goldfain
definition source: http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf
curator note: creation date: 2009-06-23T11:21:20Z
imported from: ogms.owl

disorder
type: Class
subclass of: material entity
definition: A material entity which is clinically abnormal and part of an extended organism. Disorders are the physical basis of disease.
definition editor: Albert Goldfain
definition source: http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf
curator note: creation date: 2009-06-23T11:39:44Z
imported from: ogms.owl

genetic disorder
type: Class
subclass of: disorder
definition: A disorder whose etiology involves an abnormality in the nucleotide sequence of an organism's genome.
definition editor: Albert Goldfain
definition source: http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf
curator note: creation date: 2009-06-23T11:41:14Z
imported from: ogms.owl

etiological process
type: Class
subclass of: process
definition: A process in an organism that leads to a subsequent disorder.
definition editor: Albert Goldfain
definition source: http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf
curator note: creation date: 2009-06-23T11:53:07Z
imported from: ogms.owl

bodily process
type: Class
subclass of: process
definition editor: Albert Goldfain
curator note: creation date: 2009-06-23T11:53:49Z
imported from: ogms.owl

pathological bodily process
type: Class
subclass of: bodily process
definition: A bodily process that is clinically abnormal.
definition editor: Albert Goldfain
definition source: http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf
curator note: creation date: 2009-06-23T11:54:29Z
imported from: ogms.owl

disease course
type: Class
subclass of: process
definition: The totality of all processes through which a given disease instance is realized.
definition editor: Albert Goldfain
definition source: http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf
curator note: creation date: 2009-06-23T11:55:44Z
imported from: ogms.owl

chronic disease course
type: Class
subclass of: disease course
definition: A disease course that (a) does not terminate in a return to normal homeostasis and (b) would, absent intervention, fall within abnormal homeostatic range.
definition editor: Albert Goldfain
definition source: http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf
curator note: creation date: 2009-06-23T11:56:26Z
imported from: ogms.owl

progressive disease course
type: Class
subclass of: disease course
definition: A disease course that (a) does not terminate in a return to normal homeostasis and (b) would, absent intervention, involve an increasing deviation from homeostasis.
definition editor: Albert Goldfain
definition source: http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf
curator note: creation date: 2009-06-23T11:57:09Z
imported from: ogms.owl

transient disease course
type: Class
subclass of: disease course
definition: A disease course that terminates in a return to normal homeostasis.
definition editor: Albert Goldfain
definition source: http://ontology.buffalo.edu/medo/Disease_and_Diagnosis.pdf
curator note: creation date: 2009-06-23T11:57:44Z
imported from: ogms.owl

pathological anatomical structure
type: Class
subclass of: material entity
definition: An anatomical structure (FMA) is pathological whenever (1) it has come into being as a result of changes in some pre-existing canonical anatomical structure, (2) through processes other than the expression of the normal complement of genes of an organism of the given type, and (3) is predisposed to have health-related consequences for the organism in question manifested by symptoms and signs.
definition editor: Albert Goldfain
definition source: http://ontology.buffalo.edu/bio/ISMB/ISMB_Bio-ontologies.pdf
curator note: creation date: 2009-07-13T02:14:05Z
imported from: ogms.owl

acute disease course
type: Class
subclass of: disease course
definition: a disease course with a rapid onset but typical unfolding of signs and symptoms after this rapid onset.
definition editor: Albert Goldfain
definition source: http://code.google.com/p/ogms/wiki/Meeting_notes_20100513
curator note: creation date: 2010-07-19T11:57:44Z
imported from: ogms.owl

example to be eventually removed
type: NamedIndividual

metadata complete
type: NamedIndividual
definition: Class has all its metadata, but is either not guaranteed to be in its final location in the asserted IS_A hierarchy or refers to another class that is not complete.

organizational term
type: NamedIndividual
definition: term created to ease viewing/sort terms for development purpose, and will not be included in a release

ready for release
type: NamedIndividual
definition: Class has undergone final review, is ready for use, and will be included in the next release. Any class lacking "ready_for_release" should be considered likely to change place in hierarchy, have its definition refined, or be obsoleted in the next release. Those classes deemed "ready_for_release" will also derived from a chain of ancestor classes that are also "ready_for_release."

metadata incomplete
type: NamedIndividual
definition: Class is being worked on; however, the metadata (including definition) are not complete or sufficiently clear to the branch editors.

uncurated
type: NamedIndividual
definition: Nothing done yet beyond assigning a unique class ID and proposing a preferred term.

pending final vetting
type: NamedIndividual
definition: All definitions, placement in the asserted IS_A hierarchy and required minimal metadata are complete. The class is awaiting a final review by someone other than the definition editor.

to be replaced with external ontology term
type: NamedIndividual
definition: Terms with this status should eventually replaced with a term from another ontology.
definition editor: Alan Ruttenberg
definition source: group:OBI

requires discussion
type: NamedIndividual
definition: A term that is metadata complete, has been reviewed, and problems have been identified that require discussion before release. Such a term requires editor note(s) to identify the outstanding issues.
definition editor: Alan Ruttenberg
definition source: group:OBI

bfo-spec-label
definition source: Person:Alan Ruttenberg

BFO_0000134
elucidation: To say that each spatiotemporal region s temporally_projects_onto some temporal region t is to say that t is the temporal extension of s. (axiom label in BFO2 Reference: [080-003])
elucidation: To say that spatiotemporal region s spatially_projects_onto spatial region r at t is to say that r is the spatial extent of s at t. (axiom label in BFO2 Reference: [081-003])

Axiom
annotated source: BFO_0000134
annotated property: elucidation
annotated target: To say that each spatiotemporal region s temporally_projects_onto some temporal region t is to say that t is the temporal extension of s. (axiom label in BFO2 Reference: [080-003])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/080-003

Axiom
annotated source: BFO_0000134
annotated property: elucidation
annotated target: To say that spatiotemporal region s spatially_projects_onto spatial region r at t is to say that r is the spatial extent of s at t. (axiom label in BFO2 Reference: [081-003])
has axiom label: http://purl.obolibrary.org/obo/bfo/axiom/081-003

PlainLiteral

label