An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.
An entity that has temporal parts and that happens, unfolds or develops through time.
A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.
b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])
An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.
p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])
A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same.
b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n > 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i < j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004])
b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003])
An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.
Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV.
An unsaturated fatty acid anion obtained by the deprotonation of the carboxy group of any octadecanoid.
An alcohol where the hydroxy group is attached to a saturated carbon atom adjacent to a double bond (R groups may be H, organyl, etc.).
An allylic alcohol in which the carbon atom that links the double bond to the hydroxy group is also attached to two other carbons (R4,R5 =/= H).
A 5-oxo monocarboxylic acid anion obtained by deprotonation of the carboxy group of any diastereomer of jasmonic acid; major species at pH 7.3.
An atom of an element that exhibits properties that are between those of metals and nonmetals, or that has a mixture of them. The term generally includes boron, silicon, germanium, arsenic, antimony, and tellurium, while carbon, aluminium, selenium, polonium, and astatine are less commonly included.
A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water.
A jasmonate anion resulting from the removal of a proton from the carboxy group of (+)-jasmonic acid; major species at pH 7.3.
{(1S,2S)-3-oxo-2-[(2 Z)-pent-2-en-1-yl]cyclopentyl}acetate
Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa).
An oxo monocarboxylic acid that is (3-oxocyclopentyl)acetic acid substituted by a (2Z)-pent-2-en-1-yl group at position 2 of the cyclopentane ring.
{(1S,2S)-3-oxo-2-[(2 Z)-pent-2-en-1-yl]cyclopentyl}acetic acid
A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity.
A simple monocarboxylic acid containing two carbons.
An oxygen hydride consisting of an oxygen atom that is covalently bonded to two hydrogen atoms
A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
A fatty acid with a chain length ranging from C13 to C22.
Any octanoid that is derived from jasmonate.
A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H).
A 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated.
A nitrogen oxoanion formed by loss of a proton from nitric acid. Principal species present at pH 7.3.
A compound containing at least one carbon-halogen bond (where X is a halogen atom).
A molecular entity that can transfer ("donate") an electron, a pair of electrons, an atom or a group to another molecular entity.
'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids.
An iron group element atom that has atomic number 26.
{(1R,2R)-3-oxo-2-[(2Z)-pent-2-en-1-yl]cyclopentyl}acetic acid
(1R,2R)-3-oxo-2-(2Z)-2-penten-ylcyclopentanacetic acid
(1R,2R)-3-oxo-2-(pent-2Z-enyl)-cyclopentaneacetic acid
An acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, and therefore consisting entirely of hydrogen atoms and saturated carbon atoms.
A chlorophenoxyacetate anion that is the conjugate base of (2,4-dichlorophenoxy)acetic acid, obtained by deprotonation of the carboxy group.
A member of the class of abscisic acids in which the double bond betweeen positions 2 and 3 has cis- (natural) geometry.
(2Z,4E)-5-(1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl)-3-methylpenta-2,4-dienoic acid
A monoatomic or polyatomic species having one or more elementary charges of the electron.
Any of a group of compounds, both naturally occurring and synthetic, that induce cell elongation in plant stems (from Greek alphaupsilonxialphanuomega, "to grow").
A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base).
Any benzenoid aromatic compound consisting of the benzene skeleton and its substituted derivatives.
A halogen molecular entity containing one or more atoms of chlorine.
Any organochlorine compound containing a benzene ring which is substituted by one or more chlorines.
A monocarboxylic acid anion obtained by deprotonation of the carboxy group of any chlorophenoxyacetic acid.
A monocarboxylic acid that is phenoxyacetic acid in which at least one of the phenyl hydrogens is replaced by chlorine.
Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity.
A phytohormone that promote cell division, or cytokinesis, in plant roots and shoots.
A herbicide which when sprayed or dusted on plants causes its leaves to fall off.
An azole that is either one of a pair of heterocyclic organic compounds comprising three carbon atoms and two nitrogen atoms arranged in a ring.
Any member of the class of chlorobenzenes carrying two chloro groups at unspecified positions.
Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances.
A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction.
A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances.
A role played by the molecular entity or part thereof within a biological context.
A defined linked collection of atoms or a single atom within a molecular entity.
A substance used to destroy plant pests.
A cyclic compound having as ring members atoms of carbon and at least of one other element.
Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
A compound consisting of carbon and hydrogen only.
Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-)).
Any carboxylic acid with at least one hydroxy group.
A five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton.
A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
A molecular entity that contains no carbon.
Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects.
A salt is an assembly of cations and anions.
A molecular entity having a net electric charge.
Any lipid formally derived from isoprene (2-methylbuta-1,3-diene), the skeleton of which can generally be discerned in repeated occurrence in the molecule. The skeleton of isoprenoids may differ from strict additivity of isoprene units by loss or shift of a fragment, commonly a methyl group. The class includes both hydrocarbons and oxygenated derivatives.
The jasmonates (JAs) are a group of plant hormones which help regulate plant growth and development.
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Any polyatomic entity that is an electrically neutral entity consisting of more than one atom.
An oxoacid containing a single carboxy group.
Any organic ion with a net negative charge.
An organooxygen compound with formula ROR, where R is not hydrogen.
An oxide is a chemical compound of oxygen with other chemical elements.
Any compound that has an aldehydic or ketonic group as well as a carboxylic acid group in the same molecule.
Any fatty acid anion containing at least one C-C unsaturated bond; formed by deprotonation of the carboxylic acid moiety.
Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests.
A chemical, natural or artificial, that can affect the rate of growth of a plant.
Any terpenoid derived from a sesquiterpene. The term includes compounds in which the C15 skeleton of the parent sesquiterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups).
A synthetic compound exhibiting auxin activity.
Any isoprenoid that is a natural product or related compound formally derived from isoprene units. Terpenoids may contain oxygen in various functional groups. This class is subdivided according to the number of carbon atoms in the parent terpene. The skeleton of terpenoids may differ from strict additivity of isoprene units by the loss or shift of a fragment, generally a methyl group.
A tertiary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has three other carbon atoms attached to it.
Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions.
An element whose atom has an incomplete d sub-shell, or which can give rise to cations with an incomplete d sub-shell.
Any fatty acid containing at least one C=C or C#C bond.
A cobalt group element atom that has atomic number 27.
A chlorophenoxyacetic acid that is phenoxyacetic acid in which the ring hydrogens at postions 2 and 4 are substituted by chlorines.
The conjugate base of a fatty acid, arising from deprotonation of the carboxylic acid group of the corresponding fatty acid.
The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated.
A hydroxy monocarboxylic acid anion that is acetate where the methyl group has been hydroxylated.
A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid.
Particle of zero charge, zero rest mass, spin quantum number 1, energy hnu and momentum hnu/c (h is the Planck constant, nu the frequency of radiation and c the speed of light), carrier of electromagnetic force.
A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom.
Intended use of the molecular entity or part thereof by humans.
A particle not known to have substructure.
An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system.
Any substituent group which does not contain carbon.
Any substituent group or skeleton containing carbon.
Any organic substituent group, regardless of functional type, having one free valence at a carbon atom.
A chemical entity constituting the smallest component of an element having the chemical properties of the element.
A nucleus is the positively charged central portion of an atom, excluding the orbital electrons.
Heavy nuclear particle: proton or neutron.
An anion consisting of more than one atom.
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
A nutrient is a food component that an organism uses to survive and grow.
A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms.
An agrochemical is a substance that is used in agriculture or horticulture.
A fertilizer is any substance that is added to soil or water to assist the growth of plants.
An energy-rich substance that can be transformed with release of usable energy.
Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth.
A p-block molecular entity containing any pnictogen.
Any p-block element belonging to the group 16 family of the periodic table.
Any p-block molecular entity containing a chalcogen.
An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table.
A bivalent group formed by removing two hydrogen atoms from a hydrocarbon, the free valencies of which are not engaged in a double bond.
An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity.
Any main group element atom belonging to the p-block of the periodic table.
A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid.
A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table.
Any molecule that consists of a series of atoms joined together to form a ring.
A cyclic compound having as ring members atoms of the same element only.
A homocyclic compound in which all of the ring members are carbon atoms.
Any acyclic or cyclic, saturated or unsaturated carbon compound, excluding aromatic compounds.
An aliphatic compound having a carbocyclic ring structure which may be saturated or unsaturated, but may not be a benzenoid or other aromatic system.
A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character.
An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element.
A main group molecular entity that contains one or more atoms of a p-block element.
Hydrides are chemical compounds of hydrogen with other chemical elements.
An organic compound having at least one hydroxy group attached to a carbon atom.
Any organic molecule that consists of atoms connected in the form of a ring.
A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2).
A substance used in a chemical reaction to detect, measure, examine, or produce other substances.
Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals.
A hydrocarbon of biological origin having carbon skeleton formally derived from isoprene [CH2=C(CH3)CH=CH2].
A substance that diminishes the rate of a chemical reaction.
Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene.
Any heteroorganic entity containing at least one carbon-nitrogen bond.
Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax. Natural fatty acids commonly have a chain of 4 to 28 carbons (usually unbranched and even-numbered), which may be saturated or unsaturated. By extension, the term is sometimes used to embrace all acyclic aliphatic carboxylic acids.
An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen.
Any ether in which the oxygen is attached to at least one aryl substituent.
A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated.
Any monocarboxylic acid which also contains a separate (alcoholic or phenolic) hydroxy substituent.
Any monocarboxylic acid having at least one additional oxo functional group.
Any carboxylic acid anion containing at least one oxo group.
Any monocarboxylic acid anion carrying at least one hydroxy substituent.
A cyclic ketone in which the carbocyclic ring structure which may be saturated or unsaturated, but may not be a benzenoid or other aromatic system.
Any alicyclic ketone that consists of a cyclopentane skeleton substituted by at least one oxo group.
Unsaturated C18 fatty acids and skeletally related compounds.
Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin).
Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy).
Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi.
Particle of integer spin quantum number following Bose-Einstein statistics. Bosons are named after Satyendra Nath Bose.
A subatomic particle known to have substructure (i.e. consisting of smaller particles).
Hadron is a subatomic particle which experiences the strong force.
A nucleus or any of its constituents in any of their energy states.
Any molecular entity consisting of more than one atom.
An ion consisting of more than one atom.
Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives.
Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element.
An organochlorine compound is a compound containing at least one carbon-chlorine bond.
A monoatomic or polyatomic species having one or more elementary charges of the proton.
An organochalcogen compound is a compound containing at least one carbon-chalcogen bond.
An organochalcogen compound containing at least one carbon-oxygen bond.
An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid).
A molecular entity consisting of two or more chemical elements.
Any heteroatomic molecular entity that is a chemical compound of halogen with other chemical elements.
A hormone that specifically regulates growth.
A plant growth regulator that modulates the formation of stems, leaves and flowers, as well as the development and ripening of fruit. The term includes endogenous and non-endogenous compounds (e.g. active compounds produced by bacteria on the leaf surface) as well as semi-synthetic and fully synthetic compounds.
Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms.
A monocarboxylic acid anion that is the conjugate base of phenoxyacetic acid.
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
Any chemical substance that inhibits the life-cycle of an organism.
An alkane comprising of two carbon atoms.
A liquid that can dissolve other substances (solutes) without any change in their chemical composition.
A nitrogen oxoacid of formula HNO3 in which the nitrogen atom is bonded to a hydroxy group and by equivalent bonds to the remaining two oxygen atoms.
A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds.
A polar solvent that is capable of acting as a hydron (proton) donor.
Solvent that is capable of acting as a hydron (proton) acceptor.
Self-ionizing solvent possessing both characteristics of Bronsted acids and bases.
Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own.
A drug that softens, separates, and causes desquamation of the cornified epithelium or horny layer of skin. Keratolytic drugs are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases.
A drug used to treat or prevent skin disorders or for the routine care of skin.
Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families.
Any molecular entity that contains carbon.
A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy.
A role is particular behaviour which a material entity may exhibit.
A role played by the molecular entity or part thereof within a chemical context.
Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s).
A biological role played by the molecular entity or part thereof within a biochemical context.
A role played by the molecular entity or part thereof which causes the development of a pathological process.
A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties.
Any substance introduced into a living organism with therapeutic or diagnostic purpose.
A compound arising from loss of part of the carotene skeleton (excluding retinoids)
A cyclic compound having as ring members atoms of at least two different elements.
A fatty acid anion with a chain length of C13 to C22.
A 5-oxo monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of jasmonic acid. The major species at pH 7.3.
Any member of the class of herbicides whose members contain a phenoxy or substituted phenoxy group.
A monocarboxylic acid anion that is the conjugate base of cis-abscisic acid; major species at pH 7.3.
Any apo carotenoid sesquiterpenoid that is 3-methylpenta-2,4-dienoic acid substituted at position 5 by a 1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl group and in which the acyclic double bond between positions 4 and 5 has E-configuration.
(4E)-5-(1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl)-3-methylpenta-2,4-dienoic acid
A monocarboxylic acid anion obtained by removal of a proton from the carboxy group of any member of the class of abscisic acids.
A family of nitrogen molecular entities which are highly reactive and derived from nitric oxide (.NO) and superoxide (O2.(-)) produced via the enzymatic activity of inducible nitric oxide synthase 2 (NOS2) and NADPH oxidase respectively.
Any substance which is added to food to preserve or enhance its flavour and/or appearance.
A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents.
Any organic molecular entity that is acidic and contains carbon in covalent linkage.
Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes.
A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299).
Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen.
Any molecule that consists of at least one carbon atom as part of the electrically neutral entity.
An agonist that binds to and activates abscisic acid receptors.
Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms.
Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals.
Any animal metabolite produced during a metabolic reaction in mammals.
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae).
Saccharomyces cerevisiae secondary metabolites
Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea.
Any metabolite produced by metabolism of a xenobiotic compound.
A gas in an atmosphere that absorbs and emits radiation within the thermal infrared range, so contributing to the 'greenhouse effect'.
An enzyme inhibitor which interferes with the action of an oxidoreductase (EC 1.*.*.*).
An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-OH group of donors (EC 1.1.*.*).
EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitors
inhibitor of oxidoreductase acting on CH-OH group of donor
inhibitor of oxidoreductase acting on CH-OH group of donors
inhibitors of oxidoreductase acting on CH-OH group of donor
inhibitors of oxidoreductase acting on CH-OH group of donors
oxidoreductase acting on donor CH-OH group (EC 1.1.*) inhibitor
oxidoreductase acting on donor CH-OH group (EC 1.1.*) inhibitors
oxidoreductase acting on donor CH-OH group inhibitor
oxidoreductase acting on donor CH-OH group inhibitors
EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor
An EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor that uses NAD(+) or NADP(+) as acceptor (EC 1.1.1.*).
EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+)acceptor) inhibitors
oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor (EC 1.1.1.*) inhibitor
oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor (EC 1.1.1.*) inhibitors
EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds.
Any fungal metabolite produced during a metabolic reaction in the mould, Aspergillus.
Any human metabolite produced by metabolism of a xenobiotic compound in humans.
Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of shikimate dehydrogenase (EC 1.1.1.25).
EC 1.1.1.25 (shikimate dehydrogenase) inhibitors
shikimate dehydrogenase (EC 1.1.1.25) inhibitor
shikimate dehydrogenase (EC 1.1.1.25) inhibitors
shikimate:NADP(+) 3-oxidoreductase inhibitor
shikimate:NADP(+) 3-oxidoreductase inhibitors
shikimate:NADP(+) 5-oxidoreductase inhibitor
shikimate:NADP(+) 5-oxidoreductase inhibitors
shikimate:NADP(+) oxidoreductase inhibitor
shikimate:NADP(+) oxidoreductase inhibitors
EC 1.1.1.25 (shikimate dehydrogenase) inhibitor
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants.
Any minor or unwanted substance introduced into the environment that can have undesired effects.
A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a "R" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure.
Any organic molecular entity that contains at least one C=C bond.
A monocarboxylic acid in which the carbon of the carboxy group is directly attached to a C=C or C#C bond.
alpha,beta-unsaturated monocarboxylic acids
alpha,beta-unsaturated monocarboxylic acid
Any inorganic anion with a valency of one.
A monocarboxylic acid that is the O-phenyl derivative of glycolic acid. A metabolite of 2-phenoxyethanol, it is used in the manufacture of pharmaceuticals, pesticides, fungicides and dyes.
An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill.
A Daphnia metabolite produced by the species Daphnia magna.
A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia
Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae.
Any metal which causes the onset of an allergic reaction.
An accumulation of water of varying size.
A part of an astronomical body which is primarily composed of a continuous volume of solid material, shaped by one or more environmental processes.
An environmental material primarily composed of dihydrogen oxide in its liquid form.
A portion of environmental material is a fiat object part which forms the medium or part of the medium of an environmental system.
A layer of some material entity which is adjacent to one or more of its external boundaries and directly interacts with its immediate surroundings.
A layer is a quantity of some material which is spatially continuous, has comparable thickness, and usually covers some surface.
A planetary surface is a surface layer where the solid or liquid material of a planet comes into contact with an atmosphere or outer space.
A gas that is primarily composed of hydrocarbon molecules.
Adpated from https://en.wikipedia.org/wiki/Planetary_surface
Outer space is a hard vacuum containing a low density of particles, predominantly a plasma of hydrogen and helium as well as electromagnetic radiation, magnetic fields, neutrinos, dust and cosmic rays that exists between celestial bodies.
A material entity which is composed of one or more chemical entities and has neither independent shape nor volume but tends to expand indefinitely.
A material entity which is composed of a volume of unbound positive and negative particles in roughly equal numbers, conducts electricity, and possesses internal magnetic fields.
An object which is naturally occuring, bound together by gravitational or electromagnetic forces, and surrounded by space.
A planet is an astronomical body orbiting a star or stellar remnant that is massive enough to be rounded by its own gravity, is not massive enough to cause thermonuclear fusion, and has cleared its neighbouring region of planetesimals.
An object which is composed of one or more gravitationally bound structures that are associated with a position in space.
A material part of an astronomical body.
An environmental material which is in a solid state.
An environmental material which is in a liquid state.
An astronomical body part which is composed of the combined mass of water found on, under, and over the surface of a planet.
A process whereby a volume of liquid moves due to a disequilibrium of physical forces.
A process during which a volume of water is transported due to a disequilibria in physical forces.
A quality which inheres in a astronomical body or astronomical body part by virtue of the variation in its material composition, participation in geological processes, and the variation in is land- and hydroforms.
A layer which is primarily composed of some solid material, allowing for non-solid parts such as interstitial pockets of gas or liquid.
A geographic feature which is primarily composed of a continuous volume of liquid water held in shape or sustained by an environmental process.
A surface layer which is composed primarily of solid environmental material.
A material transport process during which a volume of material is displaced due to a disequilibrium in physical forces and during which 1) the qualities that inhere in that volume and 2) the processes that are unfolding within it are largely unchanged.
A part of an astronomical body which is primarily composed of a continuous volume of liquid material, shaped by one or more environmental processes.
A part of an astronomical body which is primarily composed of a continuous volume of gaseous material, shaped by one or more environmental processes.
A part of an astronomical body which is primarily composed of a continuous volume of liquid or gaseous material, shaped by one or more environmental processes.
A surface layer where the solid or liquid material of an astronomical body comes into contact with an atmosphere or outer space.
A layer which separates two portions of environmental material which possess 1) differing compositions, 2) a discontinuity of some property, or 3) some derivative of some property in a direction normal to the interface.
An object which is composed primarily of an environmental material
An object which is composed primarily of a solid environmental material
An mass of environmental materials which has appreciable quantities of several individual materials, such that the removal of one would convert the mass into a different entity.
mass of compounded environmental materials
A solid astronomical body part which is part of the landmass of that body.
A large continuous area of land, either surrounded by sea or contiguous with another landmass.
A part of an astronomical body which is primarily composed of a continuous medium bearing liquid, gaseous, and solid material in varying quantities.
A surface layer of an astronomical body which is primarily composed of solid material and is not covered by oceans or other bodies of water.
A process in which includes the components of an environmental system as participants.
A general and temporary condition of partial or complete inundation of normally dry land areas from the overflow of inland and/or tidal waters, and/or the unusual and rapid accumulation or runoff of surface waters from any source. A great flow along a watercourse or a flow causing inundation of lands not normally covered by water.
GEMET: http://www.eionet.europa.eu/gemet/concept/3301
An environmental process which has water - in any of its states - as a participant.
A process during which material is displaced from its original location and transported either to a new location or back to the original location.
hydrocarbon-based environmental material
transferase activity, transferring phosphorus-containing groups
A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities
A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure.
A morphology quality inhering in a bearer by virtue of the bearer's relative position, shape, arrangements and connectivity of an organism's various parts; the pattern underlying its form.
A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities.
A quality which inheres in a continuant.
multiply inhering quality of a physical entity
A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity characterized by particles arranged such that their shape and volume are relatively stable.
A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity consisting of particles that have neither a defined volume nor defined shape.
A physical quality inhering in an entity exhibiting the physical characteristics of an amorphous (non-crystalline) form of matter between a gas and a solid that has a definite volume, but no definite shape.
A quality inhering in a bearer by virtue of the bearer's processing the form of a thin plate sheet or layer.
A quality inhering in a bearer by virtue of its constitution.
The propensity of a material to undergo combustion. Combustion encompasses smouldering and flaming combustion. Combustibility is usually applied to solids.
A plant experimental condition (PECO:0007359) or set of conditions describing the application of an abiotic (PECO:0007191) or biotic plant exposure (PECO:0007357) or the combinatorial application thereof.
A chemical exposure (PECO:0007189) involving the application of organic chemical(s).
A chemical exposure (PECO:0007189) involving the application of inorganic chemical(s).
An inorganic chemical exposure (PECO:0001004) involving the application of an anion or a mixture of anions (CHEBI:22563).
An organic chemical exposure (PECO:0001003) involving the application of a gas or mixture of gases.
A chemical exposure (PECO:0007189) that induces stress.
A chemical stress exposure (PECO:0001036) involving use of osmotic stress-inducing chemicals.
A chemical fertilizer exposure (PECO:0007086) involving the use of potassium fertilizer as a supplement to study plant responses.
A chemical exposure (PECO:0007189) involving the use of antibiotic for selection purposes.
An exposure involving growth in the presence of non-mineral nutrients to study various types of responses.
A plant macronutrient exposure (PECO:0007240) involving the use of the primary plant macronutrients nitrogen (N), phosphorus (P), and potassium (K).
primary plant macronutrient treatment (narrow)
An exposure involving the use of macronutrients (Ca, Mg, S) as supplement to study various types of responses. These macronutrients are used less often as fertilizers than the primary elements.
secondary macronutrient treatment (narrow)
An exposure involving the exposure of plant to elemental forms of nutrients as supplement. These are not considered essential elements.
An exposure involving growing plants in soil growth media with varying contents.
An exposure involving the growth of a plant with the pathogen Cochliobolus spp.
An exposure involving growing plants in soil growth media of varying pH levels.
An exposure involving growing plants in acidic (low pH) soil growth media.
acidic pH soil environment treatment (narrow)
An exposure involving growing plants in basic (high pH) soil growth media.
basic pH soil environment treatment (narrow)
A plant exposure (PECO:0001001) involving exposure to the various factors that comprise a geographical/regional location.
ecological environment treatment (narrow)
A growth hormone exposure (PECO:0007165) involving the use of cytokinin (or its homolog) growth hormone.
A growth hormone exposure (PECO:0007165) involving the use of ethylene (or its homolog) growth hormone.
A growth hormone exposure (PECO:0007165) involving the use of auxin (or its homolog).
A growth hormone exposure (PECO:0007165) involving the use of JA (or its homolog).
A plant nutrient exposure (PECO:0007241) involving the use of a fertilizer, a combination of plant nutrients.
Treatment involving the use of inorganic fertilizer and its components as supplements to study various types of responses.
Treatment involving the use of nitrogen fertilizer and its components as supplements to study various types of responses.
A growth hormone exposure (PECO:0007165) involving the use of abscisic acid (or its homolog).
A fungal plant exposure (PECO:0007233) involving the exposure of plant to the pathogen belonging to Ascomycetes class.
Treatment involving the exposure of plant to the pathogenic single strand RNA positive stand virus.
ssRNA positive-strand virus with no DNA stage treatment (narrow)
ssRNA positive-strand virus with no DNA stage exposure
Treatment involving the exposure of plant to the pathogenic double stranded RNA virus.
Treatment involving the exposure of plant to the pest of lepidoptera class.
An insect plant exposure (PECO:0007333) involving the exposure of a plant to an insect(s) of the Hemiptera order.
Hemiptera insect plant treatment (narrow)
Treatment involving the exposure of plant to the pathogen Gibberella spp.
An insect plant exposure (PECO:0007333) involving the exposure of a plant to an insect(s) of the Diptera order.
Dipteran insect plant treatment (narrow)
Treatment involving the exposure of plant to the pest commonly called as beetles or Coleoptera.
A plant nematode exposure (PECO:0007337) which is the exposure of a plant structure (PO:0009011) to a Meloidogyne sp. nematode.
The treatment involving an exposure to basic pH levels of the growth media.
basic pH growth media environment treatment (narrow)
basic pH growth media environment exposure
The treatment involving an exposure to acidic pH levels of the growth media.
acidic pH growth media environment treatment (narrow)
acidic pH growth media environment exposure
The treatment involving an exposure of plant to the pathogen Magnaporthe spp.
An abiotic plant exposure (PECO:0007191) involving the use of a solid or liquid substrate for growing plants or tissue-cultured plant samples.
A physical plant exposure (PECO:0007316) involving an exposure with a radiation type, intensity or quantity.
The treatment involving an exposure to a given type of radiation. Often it is in the form of electromagnetic and ionizing radiation such as light (infrared, visible or ultraviolet), x-rays, gamma rays, etc.
A chemical exposure (PECO:0007189) involving the application of one or more plant growth hormones.
A chemical exposure (PECO:0007189) involving the application of a pesticide; a chemical entity or mixture of chemical entities.
The treatment involving exposure of plants to varying levels of pH of the growth media.
The treatment involving an exposure to above optimal temperature, which may depend on the study type or the regional environment.
The treatment involving an exposure to cold or sub-optimal temperature, which may depend on the study type or the regional environment.
A physical plant exposure (PECO:0007316) involving an exposure to varying degree of temperature, which may depend on regional environment.
temperature environment treatment (narrow)
An auxin exposure (PECO:0007074) involving use of 2,4-D growth hormone and herbicide.
2,4-dichlorophenoxyacetic acid treatment (narrow)
A pesticide exposure (PECO:0007167) involving the application of a herbicide; a chemical entity or mixture of chemical entities.
A chemical exposure (PECO:0007189) involving use of salts as supplement to liquid and soil growth media to study various types of responses on their application.
An abiotic plant exposure (PECO:0007191) involving the application of chemical(s).
A plant exposure (PECO:0001001) involving the application of chemical or non-biological factors.
The treatment involving exposure of plant to the rice ragged stunt virus. It is a causal agent for rice ragged stunt disease.
rice ragged stunt virus treatment (narrow)
The treatment involving day light as the light of the sun or the artificial light in a growth chamber.
A physical plant exposure (PECO:0007316) involving an exposure of varying amounts of water and watering frequencies, which may depend on regional environment.
The treatment using red light either exclusively or as part of a supplemental light treatment involving red color light in the wavelength range of 780-622 nM.
A biotic plant exposure (PECO:0007357) involving exposure of a plant to a virus or a combination of two or more viruses.
The treatment involving exposure of plant to the pathogen Cochliobolus miyabeanus. It is a causal agent for rice Brown Spot diseaseand/or Seedling Blight (Fungal) disease.
Cochliobolus miyabeanus treatment (narrow)
The treatment involving exposure of plant to the mycoplasma pest.
The treatment using blue light either exclusively or as part of a supplemental light treatment involving blue color light in the wavelength range of 492-455 nM.
The treatment using visible light in the wavelength range of 380-780 nM.
The treatment using UV-B light either exclusively or as part of a supplemental light involving electromagnetic radiation in the wavelength range of 315-10nm.
The treatment involving exposure of plant to fluorine as supplement to study various types of responses.
The treatment involving exposure of plant to the pathogen Magnaporthe grisea. It is a causal agent for rice various forms of Blast diseases such as Collar Blast, Leaf Blast, Neck Blast, Panicle Blast and Nodal Blast disease.
The treatment involving exposure of plant to chromium as supplement to study various types of responses.
The treatment involving exposure of plant to the pathogen Gibberella fujikuroi.
The treatment involving exposure of plant to iodine as supplement to study various types of responses.
The treatment involving exposure of plant to selenium as supplement to study various types of responses.
A biotic plant exposure (PECO:0007357) involving exposure of a plant to a fungus or a combination of fungi.
The treatment involving exposure of plant to silicon as supplement to study various types of responses.
The treatment involving exposure of plant to elements that are required in tiny quantities for growth, as supplement to study various types of responses.
A plant nutrient exposure (PECO:0007241) involving the use of a plant macronutrient or combination of plant macronutrients.
A plant chemical exposure (PECO:0007189) involving a plant nutrient or a combination of plant nutrients.
The treatment involving exposure of plant to micronutrient iron as supplement to study various types of responses.
The treatment involving exposure of plant to micronutrient chlorine as supplement to study various types of responses.
The treatment involving exposure of plant to micronutrient molybdenum as supplement to study various types of responses.
The treatment involving exposure of plant to micronutrient copper as supplement to study various types of responses.
The treatment involving exposure of plant to micronutrient boron as supplement to study various types of responses.
The treatment involving exposure of plant to cobalt as supplement to study various types of responses.
The treatment involving exposure of plant to oxygen to study various types of responses.
A primary plant macronutrient exposure (PECO:0007045) involving the application of nitrogen.
nitrogen macronutrient treatment (narrow)
The treatment involving exposure of plant to macronutrient magnesium as supplement to study various types of responses.
The treatment involving exposure of plant to the pest rice whorl maggot.
The treatment involving exposure of plant to macronutrient potassium as supplement to study various types of responses.
The treatment involving exposure of plant to macronutrient sulfur as supplement to study various types of responses.
The treatment involving exposure of plant to the pest Dicladispa armigera.
The treatment involving exposure of plant to macronutrient calcium as supplement to study various types of responses.
The treatment involving exposure of plant to the pest paddy bug.
Leptocorisa oratorius treatment (narrow)
The treatment involving exposure of plant to carbon source as supplement to study various types of responses.
The treatment involving exposure of plant to the pest Cnaphalocrocis medinalis.
Cnaphalocrocis medinalis treatment (narrow)
The treatment involving exposure of plant to aluminium as supplement to study various types of responses.
The treatment involving exposure of plant to the pest green leaf hopper.
The treatment involving exposure of plant to micronutrient zinc as supplement to study various types of responses.
An abiotic plant exposure (PECO:0007191) involving the application of a physical factor such as temperature, moisture, gravity, wind, radiation, etc. or a combination thereof.
The treatment involving exposure of plant to the rice yellow mottle virus. It is a causal agent for rice yellow mottle disease.
rice yellow mottle virus treatment (narrow)
A metazoan plant treatment (PECO:0007349) involving exposure of a plant to an insect or a mixture of insects.
A plant metazoan exposure (PECO:0007349) which is the exposure of a plant structure (PO:0009011) to a nematode (NCBITaxon:6231).
The treatment involving exposure of plant to the pathogenic Fusarium spp. It is a causal agent for rice Water Mold disease also called as Seed Rot Disease or Seedling Damping-off Disease.
A biotic plant exposure (PECO:0007357) involving exposure of a plant to a metazoan organism (animal).
A plant exposure (PECO:0001001) involving the application of a biotic or biological factor such as a microbe, insect, animal, or plant or a combination thereof.
A plant exposure (PECO:0001001) and/or study type (PECO:0007231) applied to a whole plant (PO:0000003), a plant structure (PO:00090119), and/or a plant population as part of an experiment to evaluate the plant response.
The treatment involving exposure of plant to the pathogen Balansia oryzae-sativae. It is a causal agent for rice Udbatta diesase which is also called as Black Choke Disease, False Ergot Disease, Incense Rod Disease.
Balansia oryzae-sativae treatment (narrow)
The treatment involving exposure of plant to the pathogen Magnaporthe salvinii. It is a causal agent for rice stem rot disease and Seedling Blight (Fungal) Disease.
Helminthosporium sigmoideum var.irregulare. (related)
The treatment involving exposure of plant to the pest Meloidogyne javanica.
Meloidogyne javanica treatment (related)
The treatment involving exposure of plant to the pest Meloidogyne incognita.
Meloidogyne incognita treatment (related)
The treatment involving exposure of plant to micronutrient manganese as supplement to study various types of responses.
A treatment in terms of plant's exposure to the regional conditions found in the vicinity of the water bodies like, sea, river, lake etc. Growth conditions may include aerobic to anaerobic soil, salinity or toxicity in tidal areas. Treatment may include standing or flash flooding.
The treatment involving exposure of plant to macronutrient phosphorus as supplement to study various types of responses.
A growth hormone exposure (PECO:0007165) involving the use of brassinosteroid (or its homolog).
An exposure involving exposure of plant to molecular or ionic forms of hydrogen to study various types of responses.
A pesticide exposure (PECO:0007167) involving the application of an insecticide; a chemical entity or mixture of chemical entities.
An herbicide exposure (PECO:0007183) involving the use of an imidazolinone herbicide.
A process occurring within or in the vicinity of an organism that exerts some causal influence on the organism via the interaction between an exposure stimulus and an exposure receptor. The exposure stimulus may be a process, material entity or condition (for example, lack of nutrients). The exposure receptor can be an organism, organism population or a part of an organism.
MF(X)-directly_regulates->MF(Y)-enabled_by->GP(Z) => MF(Y)-has_input->GP(Y) e.g. if 'protein kinase activity'(X) directly_regulates 'protein binding activity (Y)and this is enabled by GP(Z) then X has_input Z
GP(X)-enables->MF(Y)-has_part->MF(Z) => GP(X) enables MF(Z), e.g. if GP X enables ATPase coupled transporter activity' and 'ATPase coupled transporter activity' has_part 'ATPase activity' then GP(X) enables 'ATPase activity'
GP(X)-enables->MF(Y)-part_of->BP(Z) => GP(X) involved_in BP(Z) e.g. if X enables 'protein kinase activity' and Y 'part of' 'signal tranduction' then X involved in 'signal transduction'
This rule is dubious: added as a quick fix for expected inference in GO-CAM. The problem is most acute for transmembrane proteins, such as receptors or cell adhesion molecules, which have some subfunctions inside the cell (e.g. kinase activity) and some subfunctions outside (e.g. ligand binding). Correct annotation of where these functions occurs leads to incorrect inference about the location of the whole protein. This should probably be weakened to "... -> overlaps"
If a molecular function (X) has a regulatory subfunction, then any gene product which is an input to that subfunction has an activity that directly_regulates X. Note: this is intended for cases where the regaultory subfunction is protein binding, so it could be tightened with an additional clause to specify this.
inferring direct reg edge from input to regulatory subfunction
inferring direct neg reg edge from input to regulatory subfunction
inferring direct positive reg edge from input to regulatory subfunction
effector input is compound function input
Input of effector is input of its parent MF
if effector directly regulates X, its parent MF directly regulates X
if effector directly positively regulates X, its parent MF directly positively regulates X
if effector directly negatively regulates X, its parent MF directly negatively regulates X
'causally downstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties).
'causally upstream of' and 'overlaps' should be disjoint properties (a SWRL rule is required because these are non-simple properties).